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12 results on '"Leonard, Helen M"'

1. Mothers of Children with Autism Have Different Rates of Cancer According to the Presence of Intellectual Disability in Their Child

Author

Fairthorne, Jennifer C., de Klerk, Nicholas H., Leonard, Helen M., and Whitehouse, Andrew J. O.

Abstract

Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental disorders with strong genetic components. Increasingly, research attention has focused on whether genetic factors conveying susceptibility for these conditions, also influence the risk of other health conditions, such as cancer. We examined the occurrence of hospital admissions and treatment/services for cancer in mothers of children with ASD with or without ID compared with other mothers. After linking Western Australian administrative health databases, we used Cox regression to estimate the hazard ratios (HRs) of any hospitalisations and treatment/services for cancer in these groups of mothers. Mothers of children with ASD without ID had greater risk of admissions for cancer (HR 1.29 [95% CI 1.1, 1.7]), and for treatment/services in particular (HR 1.41 [95% CI 1.0, 2.0]), than mothers of children with no ASD/ID, while mothers of children with ASD with ID were no more likely to have a cancer-related hospital admission than other mothers. Mothers of children with autism without ID had increased risk of cancer, which may relate to common genetic pathways.

Published
2016
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3. The use of cross-jurisdictional population data to investigate health indicators of child maltreatment

Author

OEDonnell, Melissa, Nassar, Natasha, Leonard, Helen M., Mathews, Richard P., Patterson, Yvonne G., and Stanley, Fiona J.

Subjects
Child sexual abuse -- Statistics, Child welfare -- Management, Hospitals -- Admission and discharge, Hospitals -- Statistics, Company business management, Health
Abstract

Retrospective cohort study using de-identified, record-linked child protection and hospital morbidity data was performed to determine the extent to which children with a hospital admission related to assault or maltreatment or to a notified sexually transmitted infection (STI) and examine injuries and conditions often associated with child maltreatment and subsequent contact with the Department for Child Protection (DCP). The health system was found to be effective in identifying and notifying real cases of maltreatment and the health data was found to play a critical role in improving maltreatment surveillance and monitor conditions and injuries associated with child maltreatment.

Published
2010

8. Inherited metabolic diseases: beyond newborn screening

Author

Leonard, Helen M. and Fletcher, Janice M.

Subjects
Genetic disorders -- Records and correspondence, Medical records -- Usage, Phenylketonuria -- Physiological aspects, Medicine -- Practice, Health
Abstract

Occurrence of inherited metabolic diseases should be recorded in a national register of cases in Australia for the benefit of researchers, clinicians and parents. Population-based databases of value in managing and long-term follow-up of persons with PKU would be of value. Women with PKU have been bearing children in the past two decades, but it is extremely important that phenylalanine levels be as normal as possible during their pregnancies, since it may act as a teratogen. The problem may not be well known and women often are lost to follow-up. It is feasible to collect data on rare disorders, not PKU only, from clinicians all over Australia, but funding is needed.

Published
1999

9. Trends in pre-existing mental health disorders among parents of infants born in Western Australia from 1990 to 2005.

Author

Anderson, Denise, Morgan, Vera A., Nassar, Natasha, Leonard, Helen M., Stanley, Fiona J., and O'Donnell, Melissa

Abstract

The article discusses a study that aims to examine the prevalence of prior and current mental health disorders in parents of infants born in Western Australia (WA) between 1990 and 2005. The study analyzed trends in the disorders over the period, and highlighted an increase in prevalence of parents with a prior history of mental health disorders in WA. The study concluded that mental health workers can identify mental illness and work with such families to offer early intervention.

Published
2013
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10. The use of cross‐jurisdictional population data to investigate health indicators of child maltreatment

Author

Fiona J. Stanley, Melissa O'Donnell, Richard Mathews, Helen Leonard, Natasha Nassar, Yvonne Patterson, O'Donnell, Melissa, Nassar, Natasha, Leonard, Helen M, Mathews, Richard P, Patterson, Yvonne G, and Stanley, Fiona J

Subjects
Child abuse, Pediatrics, medicine.medical_specialty, Adolescent, Population, Child Welfare, Poison control, malnutrition, Occupational safety and health, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Injury prevention, medicine, Humans, 0501 psychology and cognitive sciences, Child Abuse, 030212 general & internal medicine, Child, education, Retrospective Studies, child welfare, education.field_of_study, health care system, business.industry, Public health, 05 social sciences, Infant, Newborn, Infant, Child Abuse, Sexual, Western Australia, General Medicine, Hospital Records, 16. Peace & justice, 3. Good health, hospital admission, child sexual abuse, Child protection, Child, Preschool, Family medicine, Medical Record Linkage, business, 050104 developmental & child psychology, Cohort study
Abstract

Objectives: To determine the extent to which children with a hospital admission related to assault or maltreatment or to a notified sexually transmitted infection (STI) have contact with the Western Australian Department for Child Protection (DCP), and to investigate injuries and conditions often associated with child maltreatment and subsequent contact with the DCP. Design, participants and setting: Retrospective cohort study using de‐identified, record‐linked child protection and hospital morbidity data to identify all children aged 0–17 years in Western Australia between 1 January 1990 and 31 December 2005, and a subcohort of children born in WA between these dates, admissions of these children to public and private hospitals in WA, and their contact with the Western Australian DCP. Main outcome measures: Annual trends in notifications and substantiations of child maltreatment; proportion of children with assault‐related and maltreatment‐related hospital admissions resulting in notifications, substantiations, or out‐of‐home care. Results: Most children admitted for maltreatment‐related reasons (90%) had contact with the DCP, with 81% of these children being notified, 68% having maltreatment substantiated, and 50% entering out‐of‐home care. Specific injuries and conditions were associated with children who had greater contact with the DCP, including retinal haemorrhage, rib fractures, multiple injuries, STIs at under 14 years of age, and malnourishment. Conclusions: The health system effectively identifies and notifies real cases of maltreatment, and a high proportion of these are substantiated. Health data play an important role in improving maltreatment surveillance, providing opportunities to make valid comparisons over time and between jurisdictions, as well as to monitor conditions and injuries associated with child maltreatment. Refereed/Peer-reviewed

Published
2010
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11. Trends in pre-existing mental health disorders among parents of infants born in Western Australia from 1990 to 2005

Author

Denise Anderson, Helen Leonard, Fiona J. Stanley, Melissa O'Donnell, Natasha Nassar, Vera A. Morgan, O'Donnell, Melissa, Anderson, Denise, Morgan, Vera A, Nassar, Natasha, Leonard, Helen M, and Stanley, Fiona J

Subjects
Adult, Male, Parents, medicine.medical_specialty, Referral, Population, Health data, Odds, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Intervention (counseling), Prevalence, Medicine, Humans, 030212 general & internal medicine, Psychiatry, education, Socioeconomic status, Retrospective Studies, education.field_of_study, infants, business.industry, Mental Disorders, Infant, General Medicine, Western Australia, Mental illness, medicine.disease, Mental health, 030227 psychiatry, 3. Good health, Mental Health, Female, business, mental health
Abstract

Objective: To determine the prevalence of prior and current mental health disorders in parents, including trends over time. Design: A retrospective population cohort study using de-identified linked health data. Setting: Population of Western Australia. Subjects: All parents of infants born in WA between 1990 and 2005. Main outcome measures: Prevalence of prior mental health disorders in parents by birth year and by parent and child characteristics, including Aboriginality, maternal age, socioeconomic status and diagnostic groups. Results: From 1990 to 2005, there was an increase in prevalence of prior mental health disorders in mothers, from 76 per 1000 births in 1990 to 131 per 1000 births in 2005 (3.7% increase per year in the odds of children being born to mothers with a prior mental health disorder). There was also a 4.7% increase in odds per year in the prevalence of mental health contacts that had taken place in the 12 months before the birth year in mothers. In addition, there was an increase in prevalence of prior mental health disorders in fathers, from 56 per 1000 births in 1990 to 88 per 1000 births in 2005 (3.1% increase in odds per year). The diagnostic group with the highest prevalence in both mothers and fathers was substance-related disorders. Conclusions: From 1990 to 2005, there was an increase in prevalence of parents with a prior history of mental health disorders in WA. General practitioners and mental health workers can play an important role in identifying mental illness and in working with families to offer early intervention, referral and support. Refereed/Peer-reviewed

Published
2012

12. Maternal Race-Ethnicity, Immigrant Status, Country of Birth, and the Odds of a Child With Autism.

Author

Fairthorne J, de Klerk N, Leonard HM, Schieve LA, and Yeargin-Allsopp M

Abstract

The risk of autism spectrum disorder varies by maternal race-ethnicity, immigration status, and birth region. In this retrospective cohort study, Western Australian state registries and a study population of 134 204 mothers enabled us to examine the odds of autism spectrum disorder with intellectual disability in children born from 1994 to 2005 by the aforementioned characteristics. We adjusted for maternal age, parity, socioeconomic status, and birth year. Indigenous women were 50% less likely to have a child with autism spectrum disorder with intellectual disability than Caucasian, nonimmigrant women. Overall, immigrant women were 40% less likely to have a child with autism spectrum disorder with intellectual disability than nonimmigrant women. However, Black women from East Africa had more than 3.5 times the odds of autism spectrum disorder with intellectual disability in their children than Caucasian nonimmigrant women. Research is implicated on risk and protective factors for autism spectrum disorder with intellectual disability in the children of immigrant women., Competing Interests: Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Published
2017
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