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1. Magnitude of Viral Load Suppression and Associated Factors among Clients on Antiretroviral Therapy in Public Hospitals of Hawassa City Administration, Ethiopia

Author

Anito AA, Lenjebo TL, Woticha E, and Solomon F

Subjects
viral load suppression, anti-retroviral therapy, enhanced adherence counseling, hawassa, ethiopia, Immunologic diseases. Allergy, RC581-607
Abstract

Abenezer Abraham Anito,1,&ast; Tsegaye Lolaso Lenjebo,2,&ast; Eskinder Woticha,2 Fithamlak Solomon3 1Ohio State University Global One Health Initiative, Addis Ababa, Ethiopia; 2School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia; 3School of Medical Laboratory, Wolaita Sodo University, Wolaita Sodo, Ethiopia&ast;These authors contributed equally to this workCorrespondence: Abenezer Abraham Anito, Tel +251-94-142-0184 ; +251-90-201-3026, Email howmarad@gmail.comBackground: A majority of clients on first-line antiretroviral therapy with an initial high viral load will resuppress following an adherence intervention. Some sociodemographic and clinical characteristics were found to affect resuppression. Few reports on the outcome of the intervention and its associated factors in our country, with inconsistent results and some missed clinical factors of potential association, have compelled this study. The study aimed to assess the proportion of viral load suppression and associated factors among clients on antiretroviral therapy in public hospitals of Hawassa City Administration, Ethiopia.Methods: An institution-based cross-sectional study with retrospective document review was conducted among 342 participants on antiretroviral therapy enrolled for counseling since its start in November 2016. Data were captured using a pretested and structured checklist from all client charts with complete data, entered into EpiData 3.1.0 and exported to SPSS 27 for analysis. The proportion of viral load suppression was determined. Bivariate and multivariate logistic regressions were performed to identify associated factors. Statistical significance was determined at a 95% CI and P< 0.05.Results: The proportion of viral load suppression was found to be 40.9% (35.7%– 46.5%). Nevirapine-based antiretroviral treatment regimens (AOR 0.125, 95% CI 0.034– 0.464), malnutrition (AOR 0.565, 95% CI 0.329– 0.971), poor adherence (AOR 0.504, 95% CI 0.287– 0.886), lower CD4 count (AOR 0.149, 95% CI 0.071, 0.314), and fewer counseling sessions (AOR 0.330, 95% CI 0.149– 0.729) were significantly associated with viral load suppression.Conclusion: The proportion of viral load suppression is lower than that recommended by the World Health Organization. Nevirapine-based regimens, poor nutritional status, poor adherence, lower CD4 count, and fewer counseling sessions risk a lower proportion of viral load suppression. This calls for the need to devise strategies to address these factors and to revisit program implementation.Keywords: viral load suppression, antiretroviral therapy, enhanced adherence counseling, Hawassa, Ethiopia

Published
2022

2. Mapping routine measles vaccination in low- and middle-income countries

Author

Sbarra, AN, Rolfe, S, Nguyen, JQ, Earl, L, Galles, NC, Marks, A, Abbas, KM, Abbasi-Kangevari, M, Abbastabar, H, Abd-Allah, F, Abdelalim, A, Abdollahi, M, Abegaz, KH, Abiy, HAA, Abolhassani, H, Abreu, LG, Abrigo, MRM, Abushouk, AI, Accrombessi, MMK, Adabi, M, Adebayo, OM, Adekanmbi, V, Adetokunboh, OO, Adham, D, Afarideh, M, Aghaali, M, Ahmad, T, Ahmadi, R, Ahmadi, K, Ahmed, MB, Alanezi, FM, Alanzi, TM, Alcalde-Rabanal, JE, Alemnew, BT, Ali, BA, Ali, M, Alijanzadeh, M, Alinia, C, Alipoor, R, Alipour, V, Alizade, H, Aljunid, SM, Almasi, A, Almasi-Hashiani, A, Al-Mekhlafi, HM, Altirkawi, KA, Amare, B, Amini, S, Amini-Rarani, M, Amiri, F, Amit, AML, Amugsi, DA, Ancuceanu, R, Andrei, CL, Anjomshoa, M, Ansari, F, Ansari-Moghaddam, A, Ansha, MG, Antonio, CAT, Antriyandarti, E, Anvari, D, Arabloo, J, Arab-Zozani, M, Aremu, O, Armoon, B, Aryal, KK, Arzani, A, Asadi-Aliabadi, M, Asgari, S, Atafar, Z, Ausloos, M, Awoke, N, Quintanilla, BPA, Ayanore, MA, Aynalem, YA, Azadmehr, A, Azari, S, Babaee, E, Badawi, A, Badiye, AD, Bahrami, MA, Baig, AA, Bakhtiari, A, Balakrishnan, S, Banach, M, Banik, PC, Barac, A, Baradaran-Seyed, Z, Baraki, AG, Basu, S, Bayati, M, Bayou, YT, Bedi, N, Behzadifar, M, Bell, ML, Berbada, DA, Berhe, K, Bhattarai, S, Bhutta, ZA, Bijani, A, Birhanu, M, Bisanzio, D, Biswas, A, Bohlouli, S, Bolla, SR, Borzouei, S, Brady, OJ, Bragazzi, NL, Briko, AN, Briko, NI, Nagaraja, SB, Butt, ZA, Cámera, LA, Campos-Nonato, IR, Car, J, Cárdenas, R, Carvalho, F, Castaldelli-Maia, JM, Castro, F, Chattu, VK, Chehrazi, M, Chin, KL, Chu, D-T, Cook, AJ, Cormier, NM, Cunningham, B, Dahlawi, SMA, Damiani, G, Dandona, R, Dandona, L, Danovaro, MC, Dansereau, E, Daoud, F, Darwesh, AM, Darwish, AH, Das, JK, Weaver, ND, De Neve, J-W, Demeke, FM, Demis, AB, Denova-Gutiérrez, E, Desalew, A, Deshpande, A, Desta, DM, Dharmaratne, SD, Dhungana, GP, Dianatinasab, M, Diaz, D, Dipeolu, IO, Djalalinia, S, Do, HT, Dorostkar, F, Doshmangir, L, Doyle, KE, Dunachie, SJ, Duraes, AR, Kalan, ME, Leylabadlo, HE, Edinur, HA, Effiong, A, Eftekhari, A, El, Sayed, I, El, Sayed, Zaki, M, Elema, TB, Elhabashy, HR, El-Jaafary, SI, Elsharkawy, A, Emamian, MH, Enany, S, Eshrati, B, Eskandari, K, Eskandarieh, S, Esmaeilnejad, S, Esmaeilzadeh, F, Esteghamati, A, Etisso, AE, Farahmand, M, Faraon, EJA, Fareed, M, Faridnia, R, Farioli, A, Farzadfar, F, Fattahi, N, Fazlzadeh, M, Fereshtehnejad, S-M, Fernandes, E, Filip, I, Fischer, F, Foigt, NA, Folayan, MO, Foroutan, M, Fukumoto, T, Fullman, N, Gad, MM, Geberemariyam, BS, Gebrehiwot, TT, Gebrehiwot, AM, Gebremariam, KT, Gebremedhin, KB, Gebremeskel, GG, Gebreslassie, AA, Gedefaw, GA, Gezae, KE, Ghadiri, K, Ghaffari, R, Ghaffarifar, F, Ghajarzadeh, M, Gheshlagh, RG, Ghashghaee, A, Ghiasvand, H, Gholamian, A, Gilani, SA, Gill, PS, Girmay, A, Gomes, NGM, Gopalani, SV, Goulart, BNG, Grada, A, Guimarães, RA, Guo, Y, Gupta, R, Hafezi-Nejad, N, Haj-Mirzaian, A, Handiso, DW, Hanif, A, Haririan, H, Hasaballah, AI, Hasan, MM, Hasanpoor, E, Hasanzadeh, A, Hassanipour, S, Hassankhani, H, Heidari-Soureshjani, R, Henry, NJ, Herteliu, C, Heydarpour, F, Hollerich, GI, Rad, EH, Hoogar, P, Hossain, N, Hosseini, M, Hosseinzadeh, M, Househ, M, Hu, G, Huda, TM, Humayun, A, Ibitoye, SE, Ikilezi, G, Ilesanmi, OS, Ilic, IM, Ilic, MD, Imani-Nasab, MH, Inbaraj, LR, Iqbal, U, Irvani, SSN, Islam, SMS, Islam, MM, Iwu, CJ, Iwu, CCD, Jadidi-Niaragh, F, Jafarinia, M, Jahanmehr, N, Jakovljevic, M, Jalali, A, Jalilian, F, Javidnia, J, Jenabi, E, Jha, V, Ji, JS, John, O, Johnson, KB, Joukar, F, Jozwiak, JJ, Kabir, Z, Kabir, A, Kalani, H, Kalankesh, LR, Kalhor, R, Kamal, Z, Kanchan, T, Kapoor, N, Karami, M, Matin, BK, Karch, A, Karimi, SE, Kayode, GA, Karyani, AK, Keiyoro, PN, Khader, YS, Khafaie, MA, Khammarnia, M, Khan, MS, Khan, EA, Khan, J, Khan, MN, Khatab, K, Khater, MM, Khatib, MN, Khayamzadeh, M, Khazaei, M, Khazaei, S, Khosravi, A, Khubchandani, J, Kianipour, N, Kim, YJ, Kimokoti, RW, Kinyoki, DK, Kisa, A, Kisa, S, Kolola, T, Komaki, H, Kosen, S, Koul, PA, Koyanagi, A, Kraemer, MUG, Krishan, K, Kuate Defo, B, Kumar, M, Kumar, P, Kumar, GA, Kusuma, D, La Vecchia, C, Lacey, B, Lad, SD, Lal, DK, Lam, F, Lami, FH, Lansingh, VC, Larson, HJ, Lasrado, S, Lee, SWH, Lee, PH, LeGrand, KE, Lenjebo, TL, Li, S, Liang, X, Liu, PY, Lopukhov, PD, Machado, DB, Mahasha, PW, Mahdavi, MM, Maheri, M, Mahotra, NB, Maled, V, Maleki, S, Malik, MA, Malta, DC, Mansour-Ghanaei, F, Mansouri, B, Mansourian, M, Mansournia, MA, Martins-Melo, FR, Masaka, A, Mayala, BK, Mehndiratta, MM, Mehri, F, Mehta, KM, Memiah, PTN, Mendoza, W, Menezes, RG, Mengesha, MB, Mengesha, EW, Mestrovic, T, Mihretie, KM, Miller-Petrie, MK, Mills, EJ, Milne, GJ, Mirabi, P, Mirrakhimov, EM, Mirzaei, R, Mirzaei, M, Mirzaei, HR, Mirzaei, H, Mirzaei-Alavijeh, M, Moazen, B, Moghadaszadeh, M, Mohamadi, E, Mohammad, DK, Mohammad, Y, Mohammad, KA, Mohammad Gholi Mezerji, N, Mohammadbeigi, A, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mohammed, S, Mohammed, AS, Mohammed, H, Mohebi, F, Mokdad, AH, Monasta, L, Moosavi, MA, Moosazadeh, M, Moradi, G, Moradi, M, Moradi-Joo, M, Moradi-Lakeh, M, Moradzadeh, R, Moraga, P, Mosapour, A, Mouodi, S, Mousavi, SM, Khaneghah, AM, Mueller, UO, Muluneh, AG, Munro, SB, Murray, CJL, Murthy, GVS, Muthupandian, S, Naderi, M, Nagarajan, AJ, Naghavi, M, Nangia, V, Nansseu, JR, Nayak, VC, Nazari, J, Ndwandwe, DE, Negoi, I, Ngunjiri, JW, Nguyen, HLT, Nguyen, CTK, Nguyen, TH, Nigatu, YT, Nikbakhsh, R, Nikfar, S, Nikpoor, AR, Ningrum, DNA, Nnaji, CA, Oh, I-H, Oladnabi, M, Olagunju, AT, Olusanya, JO, Olusanya, BO, Bali, AO, Omer, MO, Onwujekwe, OE, Osgood-Zimmerman, AE, Owolabi, MO, P, A, M, Padubidri, JR, Pakshir, K, Pana, A, Pandey, A, Pando-Robles, V, Pashaei, T, Pasupula, DK, Paternina-Caicedo, AJ, Patton, GC, Pazoki Toroudi, H, Pepito, VCF, Pescarini, JM, Pigott, DM, Pilgrim, T, Pirsaheb, M, Poljak, M, Postma, MJ, Pourjafar, H, Pourmalek, F, Pourmirza, Kalhori, R, Prada, SI, Prakash, S, Quazi Syed, Z, Quintana, H, Rabiee, N, Rabiee, M, Radfar, A, Rafiei, A, Rahim, F, Rajati, F, Rameto, MA, Ramezanzadeh, K, Ranabhat, CL, Rao, SJ, Rasella, D, Rastogi, P, Rathi, P, Rawaf, S, Rawaf, DL, Rawal, L, Rawassizadeh, R, Rawat, R, Renjith, V, Renzaho, AMN, Reshmi, B, Reta, MA, Rezaei, N, Rezai, MS, Rezapour, A, Riahi, SM, Ribeiro, AI, Rickard, J, Rios-Blancas, M, Rios-González, CM, Roever, L, Rostamian, M, Rubino, S, Rwegerera, GM, Saad, AM, Saadatagah, S, Sabour, S, Sadeghi, E, Moghaddam, SS, Saeidi, S, Sagar, R, Sahebkar, A, Sahraian, MA, Sajadi, SM, Salahshoor, MR, Salam, N, Salem, H, Salem, MR, Salomon, JA, Kafil, HS, Sambala, EZ, Samy, AM, Saraswathy, SYI, Sarmiento-Suárez, R, Saroshe, S, Sartorius, B, Sarveazad, A, Sathian, B, Sathish, T, Schaeffer, LE, Schwebel, DC, Senthilkumaran, S, Shabaninejad, H, Shahabi, S, Shaheen, AA, Shaikh, MA, Shalash, AS, Shams-Beyranvand, M, Shamsi, MB, Shamsizadeh, M, Sharafi, K, Sharifi, H, Sheikh, A, Sheikhtaheri, A, Shetty, RS, Shiferaw, WS, Shigematsu, M, Shin, JI, Shirkoohi, R, Siabani, S, Siddiqi, TJ, Silverberg, JIS, Simonetti, B, Singh, JA, Sinha, DN, Sinke, AH, Soheili, A, Sokhan, A, Soltani, S, Soofi, M, Sorrie, MB, Soyiri, IN, Spotin, A, Spurlock, EE, Sreeramareddy, CT, Sudaryanto, A, Sufiyan, MB, Suleria, HAR, Abdulkader, RS, Taherkhani, A, Tapak, L, Taveira, N, Taymoori, P, Tefera, YM, Tehrani-Banihashemi, A, Teklehaimanot, BF, Tekulu, GH, Tesfay, BE, Tessema, ZT, Tessema, B, Thankappan, KR, Tohidinik, HR, Topor-Madry, R, Tovani-Palone, MR, Tran, BX, Uddin, R, Ullah, I, Umeokonkwo, CD, Unnikrishnan, B, Upadhyay, E, Usman, MS, Vaezi, M, Valadan, Tahbaz, S, Valdez, PR, Vasseghian, Y, Veisani, Y, Violante, FS, Vollmer, S, Waheed, Y, Wakefield, J, Wang, Y, Wang, Y-P, Weldesamuel, GT, Werdecker, A, Westerman, R, Wiangkham, T, Wiens, KE, Wiysonge, CS, Woldu, G, Wondafrash, DZ, Wonde, TE, Wu, A-M, Yadollahpour, A, Jabbari, SHY, Yamada, T, Yaya, S, Yazdi-Feyzabadi, V, Yeheyis, TY, Yeshaw, Y, Yilgwan, CS, Yip, P, Yonemoto, N, Younis, MZ, Yousefi, Z, Yousefifard, M, Yousefinezhadi, T, Yu, C, Yusefzadeh, H, Zadey, S, Zahirian, Moghadam, T, Zaki, L, Zaman, SB, Zamani, M, Zamanian, M, Zandian, H, Zangeneh, A, Zarei, F, Zerfu, TA, Zhang, Y, Zhang, Z-J, Zhao, X-JG, Zhou, M, Ziapour, A, Hay, SI, Lim, SS, Mosser, JF, Local Burden of Disease Vaccine Coverage Collaborators, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), HUS Comprehensive Cancer Center, Clinicum, Department of Oncology, Sbarra, Alyssa N., Rolfe, Sam, Nguyen, Jason Q., Earl, Lucas, Ahmed, MB, Mosser, Jonathan F, Collaborators, Local Burden of Disease Vaccine Coverage, Bill & Melinda Gates Foundation, Alexander von Humboldt-Stiftung, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Universiti Sains Malaysia (Malasia), Panjab University (India), NIHR - Oxford Biomedical Research Centre (Reino Unido), Australian Research Council, Instituto de Saúde Pública da Universidade do Porto, Local Burden Dis Educ Attainment C, Local Burden of Disease Vaccine Coverage Collaborator, and Violante FS

Subjects
and promotion of well-being, Vacunación Masiva, Internationality, Disease prevention, children under 5 years old, Geographic Mapping, Rural Health, medicine.disease_cause, Cross-reactivity, 0302 clinical medicine, RA0421, Vaccination Refusal, 030212 general & internal medicine, Child, immunity patterns, Pediatric, 0303 health sciences, Public health, Multidisciplinary, biology, Vaccination, Uncertainty, IMMUNIZATION, 3142 Public health care science, environmental and occupational health, COVERAGE, 3. Good health, TIME, 3.4 Vaccines, Child, Preschool, Infectious diseases, A990 Medicine and Dentistry not elsewhere classified, Antibody, Engineering sciences. Technology, AFRICA, General Science & Technology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, 610 Medicine & health, Global Vaccine Action Plan (GVAP), Local Burden of Disease Vaccine Coverage Collaborators, Article, Vaccine Related, 03 medical and health sciences, measles vaccine, Measels, Low- and middle-income countries, Local burden of disease, Clinical Research, medicine, Humans, Healthcare Disparities, Preschool, PROGRESS, 030304 developmental biology, business.industry, MORTALITY, Developed Countries, Prevention, Comment, Vacunación, Urban Health, Prevention of disease and conditions, Virology, Coronavirus, Good Health and Well Being, Cobertura de Vacunación, biology.protein, Immunization, business, Measles
Abstract

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 × 5-km2 pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children., Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Published
2021

3. Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017

Author

James, SL, Castle, CD, Dingels, ZV, Fox, JT, Hamilton, EB, Liu, Z, S Roberts, NL, Sylte, DO, Henry, NJ, LeGrand, KE, Abdelalim, A, Abdoli, A, Abdollahpour, I, Abdulkader, RS, Abedi, A, Abosetugn, AE, Abushouk, AI, Adebayo, OM, Agudelo-Botero, M, Ahmad, T, Ahmed, R, Ahmed, MB, Eddine Aichour, MT, Alahdab, F, Alamene, GM, Alanezi, FM, Alebel, A, Alema, NM, Alghnam, SA, Al-Hajj, S, Ali, BA, Ali, S, Alikhani, M, Alinia, C, Alipour, V, Aljunid, SM, Almasi-Hashiani, A, Almasri, NA, Altirkawi, K, Abdeldayem Amer, YS, Amini, S, Loreche Amit, AM, Andrei, CL, Ansari-Moghaddam, A, T Antonio, CA, Yaw Appiah, SC, Arabloo, J, Arab-Zozani, M, Arefi, Z, Aremu, O, Ariani, F, Arora, A, Asaad, M, Asghari, B, Awoke, N, Ayala Quintanilla, BP, Ayano, G, Ayanore, MA, Azari, S, Azarian, G, Badawi, A, Badiye, AD, Bagli, E, Baig, AA, Bairwa, M, Bakhtiari, A, Balachandran, A, Banach, M, Banerjee, SK, Banik, PC, Banstola, A, Barker-Collo, SL, Bärnighausen, TW, Barrero, LH, Barzegar, A, Bayati, M, Baye, BA, Bedi, N, Behzadifar, M, Bekuma, TT, Belete, H, Benjet, C, Bennett, DA, Bensenor, IM, Berhe, K, Bhardwaj, P, Bhat, AG, Bhattacharyya, K, Bibi, S, Bijani, A, Bin Sayeed, MS, Borges, G, Borzì, AM, Boufous, S, Brazinova, A, Briko, NI, Budhathoki, SS, Car, J, Cárdenas, R, Carvalho, F, Castaldelli-Maia, JM, Castañeda-Orjuela, CA, Castelpietra, G, Catalá-López, F, Cerin, E, Chandan, JS, Chanie, WF, Chattu, SK, Chattu, VK, Chatziralli, I, Chaudhary, N, Cho, DY, Kabir Chowdhury, MA, Chu, D-T, Colquhoun, SM, Constantin, M-M, Costa, VM, Damiani, G, Daryani, A, Dávila-Cervantes, CA, Demeke, FM, Demis, AB, Demoz, GT, Demsie, DG, Derakhshani, A, Deribe, K, Desai, R, Nasab, MD, da Silva, DD, Dibaji Forooshani, ZS, Doyle, KE, Driscoll, TR, Dubljanin, E, Adema, BD, Eagan, AW, Eftekhari, A, Ehsani-Chimeh, E, Sayed Zaki, ME, Elemineh, DA, El-Jaafary, SI, El-Khatib, Z, Ellingsen, CL, Emamian, MH, Endalew, DA, Eskandarieh, S, Faris, PS, Faro, A, Farzadfar, F, Fatahi, Y, Fekadu, W, Ferede, TY, Fereshtehnejad, S-M, Fernandes, E, Ferrara, P, Feyissa, GT, Filip, I, Fischer, F, Folayan, MO, Foroutan, M, Francis, JM, Franklin, RC, Fukumoto, T, Geberemariyam, BS, Gebre, AK, Gebremedhin, KB, Gebremeskel, GG, Gebremichael, B, Gedefaw, GA, Geta, B, Ghafourifard, M, Ghamari, F, Ghashghaee, A, Gholamian, A, Gill, TK, Goulart, AC, Grada, A, Grivna, M, Mohialdeen Gubari, MI, Guimarães, RA, Guo, Y, Gupta, G, Haagsma, JA, Hafezi-Nejad, N, Bidgoli, HH, Hall, BJ, Hamadeh, RR, Hamidi, S, Haro, JM, Hasan, MM, Hasanzadeh, A, Hassanipour, S, Hassankhani, H, Hassen, HY, Havmoeller, R, Hayat, K, Hendrie, D, Heydarpour, F, Híjar, M, Ho, HC, Hoang, CL, Hole, MK, Holla, R, Hossain, N, Hosseinzadeh, M, Hostiuc, S, Hu, G, Ibitoye, SE, Ilesanmi, OS, Ilic, I, Ilic, MD, Inbaraj, LR, Indriasih, E, Naghibi Irvani, SS, Shariful Islam, SM, Islam, MM, Ivers, RQ, Jacobsen, KH, Jahani, MA, Jahanmehr, N, Jakovljevic, M, Jalilian, F, Jayaraman, S, Jayatilleke, AU, Jha, RP, John-Akinola, YO, Jonas, JB, Joseph, N, Joukar, F, Jozwiak, JJ, Jungari, SB, Jürisson, M, Kabir, A, Kadel, R, Kahsay, A, Kalankesh, LR, Kalhor, R, Kamil, TA, Kanchan, T, Kapoor, N, Karami, M, Kasaeian, A, Kassaye, HG, Kavetskyy, T, Kebede, HK, Keiyoro, PN, Kelbore, AG, Kelkay, B, Khader, YS, Khafaie, MA, Khalid, N, Khalil, IA, Khalilov, R, Khammarnia, M, Khan, EA, Khan, M, Khanna, T, Khazaie, H, Shadmani, FK, Khundkar, R, Kiirithio, DN, Kim, Y-E, Kim, D, Kim, YJ, Kisa, A, Kisa, S, Komaki, H, M Kondlahalli, SK, Korshunov, VA, Koyanagi, A, G Kraemer, MU, Krishan, K, Bicer, BK, Kugbey, N, Kumar, V, Kumar, N, Kumar, GA, Kumar, M, Kumaresh, G, Kurmi, OP, Kuti, O, Vecchia, CL, Lami, FH, Lamichhane, P, Lang, JJ, Lansingh, VC, Laryea, DO, Lasrado, S, Latifi, A, Lauriola, P, Leasher, JL, Huey Lee, SW, Lenjebo, TL, Levi, M, Li, S, Linn, S, Liu, X, Lopez, AD, Lotufo, PA, Lunevicius, R, Lyons, RA, Madadin, M, El Razek, MMA, Mahotra, NB, Majdan, M, Majeed, A, Malagon-Rojas, JN, Maled, V, Malekzadeh, R, Malta, DC, Manafi, N, Manafi, A, Manda, A-L, Manjunatha, N, Mansour-Ghanaei, F, Mansouri, B, Mansournia, MA, Maravilla, JC, March, LM, Mason-Jones, AJ, Masoumi, SZ, Massenburg, BB, Maulik, PK, Meles, GG, Melese, A, Melketsedik, ZA, N Memiah, PT, Mendoza, W, Menezes, RG, Mengesha, MB, Mengesha, MM, Meretoja, TJ, Meretoja, A, Merie, HE, Mestrovic, T, Miazgowski, B, Miazgowski, T, Miller, TR, Mini, GK, Mirica, A, Mirrakhimov, EM, Mirzaei-Alavijeh, M, Mithra, P, Moazen, B, Moghadaszadeh, M, Mohamadi, E, Mohammad, Y, Mohammad, KA, Darwesh, AM, Gholi Mezerji, NM, Mohammadian-Hafshejani, A, Mohammadoo-Khorasani, M, Mohammadpourhodki, R, Mohammed, S, Mohammed, JA, Mohebi, F, Molokhia, M, Monasta, L, Moodley, Y, Moosazadeh, M, Moradi, M, Moradi, G, Moradi-Lakeh, M, Moradpour, F, Morawska, L, Velásquez, IM, Morisaki, N, Morrison, SD, Mossie, TB, Muluneh, AG, Murthy, S, Musa, KI, Mustafa, G, Nabhan, AF, Nagarajan, AJ, Naik, G, Naimzada, MD, Najafi, F, Nangia, V, Nascimento, BR, Naserbakht, M, Nayak, V, Ndwandwe, DE, Negoi, I, Ngunjiri, JW, Nguyen, CT, Thi Nguyen, HL, Nikbakhsh, R, Anggraini Ningrum, DN, Nnaji, CA, Nyasulu, PS, Ogbo, FA, Oghenetega, OB, Oh, I-H, Okunga, EW, Olagunju, AT, Olagunju, TO, Bali, AO, Onwujekwe, OE, Asante, KO, Orpana, HM, Ota, E, Otstavnov, N, Otstavnov, SS, A, MP, Padubidri, JR, Pakhale, S, Pakshir, K, Panda-Jonas, S, Park, E-K, Patel, SK, Pathak, A, Pati, S, Patton, GC, Paulos, K, Peden, AE, Filipino Pepito, VC, Pereira, J, Pham, HQ, Phillips, MR, Pinheiro, M, Polibin, RV, Polinder, S, Poustchi, H, Prakash, S, Angga Pribadi, DR, Puri, P, Syed, ZQ, Rabiee, M, Rabiee, N, Radfar, A, Rafay, A, Rafiee, A, Rafiei, A, Rahim, F, Rahimi, S, Rahimi-Movaghar, V, Rahman, MA, Rajabpour-Sanati, A, Rajati, F, Rakovac, I, Ranganathan, K, Rao, SJ, Rashedi, V, Rastogi, P, Rathi, P, Rawaf, S, Rawal, L, Rawassizadeh, R, Renjith, V, N Renzaho, AM, Resnikoff, S, Rezapour, A, Ribeiro, AI, Rickard, J, Rios González, CM, Ronfani, L, Roshandel, G, Saad, AM, Sabde, YD, Sabour, S, Saddik, B, Safari, S, Safari-Faramani, R, Safarpour, H, Safdarian, M, Sajadi, SM, Salamati, P, Salehi, F, Zahabi, SS, Rashad Salem, MR, Salem, H, Salman, O, Salz, I, Samy, AM, Sanabria, J, Riera, LS, Santric Milicevic, MM, Sarker, AR, Sarveazad, A, Sathian, B, Sawhney, M, Sawyer, SM, Saxena, S, Sayyah, M, Schwebel, DC, Seedat, S, Senthilkumaran, S, Sepanlou, SG, Seyedmousavi, S, Sha, F, Shaahmadi, F, Shahabi, S, Shaikh, MA, Shams-Beyranvand, M, Shamsizadeh, M, Sharif-Alhoseini, M, Sharifi, H, Sheikh, A, Shigematsu, M, Shin, JI, Shiri, R, Siabani, S, Sigfusdottir, ID, Singh, PK, Singh, JA, Sinha, DN, Smarandache, C-G, R Smith, EU, Soheili, A, Soleymani, B, Soltanian, AR, Soriano, JB, Sorrie, MB, Soyiri, IN, Stein, DJ, Stokes, MA, Sufiyan, MB, Rasul Suleria, HA, Sykes, BL, Tabarés-Seisdedos, R, Tabb, KM, Taddele, BW, Tadesse, DB, Tamiru, AT, Tarigan, IU, Tefera, YM, Tehrani-Banihashemi, A, Tekle, MG, Tekulu, GH, Tesema, AK, Tesfay, BE, Thapar, R, Tilahune, AB, Tlaye, KG, Tohidinik, HR, Topor-Madry, R, Tran, BX, Tran, KB, Tripathy, JP, Tsai, AC, Car, LT, Ullah, S, Ullah, I, Umar, M, Unnikrishnan, B, Upadhyay, E, Uthman, OA, Valdez, PR, Vasankari, TJ, Venketasubramanian, N, Violante, FS, Vlassov, V, Waheed, Y, Weldesamuel, GT, Werdecker, A, Wiangkham, T, Wolde, HF, Woldeyes, DH, Wondafrash, DZ, Wondmeneh, TG, Wondmieneh, AB, Wu, A-M, Yadav, R, Yadollahpour, A, Yano, Y, Yaya, S, Yazdi-Feyzabadi, V, Yip, P, Yisma, E, Yonemoto, N, Yoon, S-J, Youm, Y, Younis, MZ, Yousefi, Z, Yu, Y, Yu, C, Yusefzadeh, H, Moghadam, TZ, Zaidi, Z, Zaman, SB, Zamani, M, Zamanian, M, Zandian, H, Zarei, A, Zare, F, Zhang, Z-J, Zhang, Y, Zodpey, S, Dandona, L, Dandona, R, Degenhardt, L, Dharmaratne, SD, Hay, SI, Mokdad, AH, Reiner, RC, Sartorius, B, and Vos, T

Subjects
Life Expectancy, Incidence, burden of disease, descriptive epidemiology, global, Humans, Wounds and Injuries, Public Health, Quality-Adjusted Life Years, Morbidity, Global Health, 1106 Human Movement and Sports Sciences, 1117 Public Health and Health Services, 1701 Psychology, Global Burden of Disease
Abstract

BACKGROUND: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries.; METHODS: We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs).; FINDINGS: In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100000. In 1990, there were 354064302 (95% uncertainty interval: 338174876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100000 to 3267 (3058 to 3505).; INTERPRETATION: Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care. © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.

Published
2020

4. Determinants of respectful maternity care among women who gave childbirth in Southern Ethiopia.

Author

Utalo D, Israel E, Lenjebo TL, Aynalem A, and Darebo TD

Subjects
Adult, Female, Humans, Infant, Newborn, Pregnancy, Young Adult, Cross-Sectional Studies, Delivery, Obstetric, Ethiopia epidemiology, Health Facilities, Quality of Health Care, Maternal Health Services
Abstract

Background: Having a good provision of respectful maternity care (RMC) to a woman who gives childbirth is a crucial component of maternal health care to result in positive maternal and neonatal outcomes. Disrespect and lack of women-centered care in birth discourage a woman from seeking healthcare during childbirth contributing to poor healthcare-seeking behaviour and dissatisfaction with the maternity service. The current study aimed to assess key determinants of RMC during childbirth at selected public health facilities of the Gofa zone, Southern Ethiopia., Methods: A cross-sectional study design was conducted from March to April 2021 among 390 women who gave birth in eight randomly selected public health facilities of Gofa zone, Southern Ethiopia. The level of RMC was measured using structured exit interview items. A structured-interviewer-administered questionnaire was used to collect data and then entered into Epi-data version 4.6 and exported to SPSS version 25 for further analysis. Bivariate and multivariate logistic regression analyses were used to identify determinants of RMC among women., Results: A total of 390 women responded to the exit interview making a response rate of 100%. The mean (± SD) age of the 390 women was 27.9 (± 4.85) years. The overall prevalence of women who received RMC was 40.5%, 95% CI (36-45%). Two hundred and ninety-seven (76.2%; n = 297/390) women had antenatal care (ANC) attendance in the index pregnancy. A woman who had planned pregnancy (AOR = 1.72, CI: 1.04, 2.85), planned to deliver in a health facility (AOR = 1.68, CI: 1.00, 2.81), presence of familial support (AOR = 2.04, CI: 1.20, 3.48), and had information about service availability (AOR = 4.44, CI: 2.09, 9.42) were associated with RMC among women., Conclusion: The provision of respectful maternity care in the study area was low when compared with local studies. Planned pregnancy, plan to deliver in a health facility, family support, and presence of information about service availability were factors associated with RMC among women. More attention should be given to training and supportive supervision of health care professionals on respectful maternity care and its standards to increase service uptake and make service more women-centred., (© 2024. The Author(s).)

Published
2024
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5. Pressure injury prevention practice and associated factors among nurses at Wolaita Sodo University Teaching and Referral Hospital, South Ethiopia: a cross-sectional study.

Author

Awoke N, Tekalign T, Arba A, and Lenjebo TL

Subjects
Humans, Cross-Sectional Studies, Ethiopia, Surveys and Questionnaires, Universities, Hospitals, Referral and Consultation, Pressure Ulcer
Abstract

Objective: The prevention of pressure injury is of great importance in providing quality care to patients, as it has been reported that approximately 95% of all pressure injury are preventable. Nurses working in clinical settings play a key role in identifying patients at risk and administering preventative care. Therefore, this study examines pressure injury prevention practices among nurses., Design: Cross-sectional study design., Setting: Wolaita Sodo University Teaching and Referral Hospital, Ethiopia., Participants: 240 nurses., Main Outcome Measures: Pressure injury prevention practices among nurses., Result: Among nurses, 37.9% had good pressure injury prevention practices. The factors associated with pressure injury prevention practices included having a bachelor's degree or higher (adjusted odds ratio (AOR)=2.18; 95% CI 1.12 to 4.25), having more than 10 years of nursing experience (AOR=3.44; 95% CI 1.41 to 8.37), lacking subject knowledge (AOR=0.49; 95% CI 0.27 to 0.91) and being over the age of 40 (AOR=0.55; 95% CI 0.09 to 0.35)., Conclusion: The majority of nurses reported having a limited level of pressure injury prevention practice. Since pressure ulcer prevention practice is majorly the role of nurses. Upgrading the educational level of the nurses through continuous professional development opportunities can improve the preventive practice of pressure ulcer injury by increasing the knowledge and skill gained during the vocational training., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2022
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6. Global Burden of Anxiety and Depression among Cystic Fibrosis Patient: Systematic Review and Meta-Analysis.

Author

Guta MT, Tekalign T, Awoke N, Fite RO, Dendir G, and Lenjebo TL

Abstract

Aims: This systemic review and meta-analysis were aimed at determining the level of anxiety and depression among cystic fibrosis patients in the world., Methods: We conducted a systematic search of published studies from PubMed, EMBASE, MEDLINE, Cochrane, Scopus, Web of Science, CINAHL, and manually on Google Scholar. This meta-analysis follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The quality of studies was assessed by the modified Newcastle-Ottawa Scale (NOS). Meta-analysis was carried out using a random-effects method using the STATA™ Version 14 software. Trim and fill analysis was done to correct the presence of significant publication bias., Result: From 419,820 obtained studies, 26 studies from 2 different parts of the world including 9766. The overall global pooled prevalence of anxiety and depression after correction for publication bias by trim and fill analysis was found to be 24.91(95% CI: 20.8-28.9) for anxiety. The subgroup analyses revealed with the lowest prevalence, 23.59%, (95% CI: 8.08, 39.09)) in North America and the highest, 26.77%, (95% CI: 22.5, 31.04) seen in Europe for anxiety and with the highest prevalence, 18.67%, (95% CI: 9.82, 27.5) in North America and the lowest, 13.27%, (95% CI: -10.05, 16.5) seen in Europe for depression., Conclusion: The global prevalence of anxiety and depression among cystic fibrosis patients is common. Therefore, close monitoring of the patient, regularly screening for anxiety and depression, and appropriate prevention techniques is recommended., Competing Interests: All the authors declare that they have no competing interests., (Copyright © 2021 Mistire Teshome Guta et al.)

Published
2021
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7. Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.

Author

James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, S Roberts NL, Sylte DO, Henry NJ, LeGrand KE, Abdelalim A, Abdoli A, Abdollahpour I, Abdulkader RS, Abedi A, Abosetugn AE, Abushouk AI, Adebayo OM, Agudelo-Botero M, Ahmad T, Ahmed R, Ahmed MB, Eddine Aichour MT, Alahdab F, Alamene GM, Alanezi FM, Alebel A, Alema NM, Alghnam SA, Al-Hajj S, Ali BA, Ali S, Alikhani M, Alinia C, Alipour V, Aljunid SM, Almasi-Hashiani A, Almasri NA, Altirkawi K, Abdeldayem Amer YS, Amini S, Loreche Amit AM, Andrei CL, Ansari-Moghaddam A, T Antonio CA, Yaw Appiah SC, Arabloo J, Arab-Zozani M, Arefi Z, Aremu O, Ariani F, Arora A, Asaad M, Asghari B, Awoke N, Ayala Quintanilla BP, Ayano G, Ayanore MA, Azari S, Azarian G, Badawi A, Badiye AD, Bagli E, Baig AA, Bairwa M, Bakhtiari A, Balachandran A, Banach M, Banerjee SK, Banik PC, Banstola A, Barker-Collo SL, Bärnighausen TW, Barrero LH, Barzegar A, Bayati M, Baye BA, Bedi N, Behzadifar M, Bekuma TT, Belete H, Benjet C, Bennett DA, Bensenor IM, Berhe K, Bhardwaj P, Bhat AG, Bhattacharyya K, Bibi S, Bijani A, Bin Sayeed MS, Borges G, Borzì AM, Boufous S, Brazinova A, Briko NI, Budhathoki SS, Car J, Cárdenas R, Carvalho F, Castaldelli-Maia JM, Castañeda-Orjuela CA, Castelpietra G, Catalá-López F, Cerin E, Chandan JS, Chanie WF, Chattu SK, Chattu VK, Chatziralli I, Chaudhary N, Cho DY, Kabir Chowdhury MA, Chu DT, Colquhoun SM, Constantin MM, Costa VM, Damiani G, Daryani A, Dávila-Cervantes CA, Demeke FM, Demis AB, Demoz GT, Demsie DG, Derakhshani A, Deribe K, Desai R, Nasab MD, da Silva DD, Dibaji Forooshani ZS, Doyle KE, Driscoll TR, Dubljanin E, Adema BD, Eagan AW, Eftekhari A, Ehsani-Chimeh E, Sayed Zaki ME, Elemineh DA, El-Jaafary SI, El-Khatib Z, Ellingsen CL, Emamian MH, Endalew DA, Eskandarieh S, Faris PS, Faro A, Farzadfar F, Fatahi Y, Fekadu W, Ferede TY, Fereshtehnejad SM, Fernandes E, Ferrara P, Feyissa GT, Filip I, Fischer F, Folayan MO, Foroutan M, Francis JM, Franklin RC, Fukumoto T, Geberemariyam BS, Gebre AK, Gebremedhin KB, Gebremeskel GG, Gebremichael B, Gedefaw GA, Geta B, Ghafourifard M, Ghamari F, Ghashghaee A, Gholamian A, Gill TK, Goulart AC, Grada A, Grivna M, Mohialdeen Gubari MI, Guimarães RA, Guo Y, Gupta G, Haagsma JA, Hafezi-Nejad N, Bidgoli HH, Hall BJ, Hamadeh RR, Hamidi S, Haro JM, Hasan MM, Hasanzadeh A, Hassanipour S, Hassankhani H, Hassen HY, Havmoeller R, Hayat K, Hendrie D, Heydarpour F, Híjar M, Ho HC, Hoang CL, Hole MK, Holla R, Hossain N, Hosseinzadeh M, Hostiuc S, Hu G, Ibitoye SE, Ilesanmi OS, Ilic I, Ilic MD, Inbaraj LR, Indriasih E, Naghibi Irvani SS, Shariful Islam SM, Islam MM, Ivers RQ, Jacobsen KH, Jahani MA, Jahanmehr N, Jakovljevic M, Jalilian F, Jayaraman S, Jayatilleke AU, Jha RP, John-Akinola YO, Jonas JB, Joseph N, Joukar F, Jozwiak JJ, Jungari SB, Jürisson M, Kabir A, Kadel R, Kahsay A, Kalankesh LR, Kalhor R, Kamil TA, Kanchan T, Kapoor N, Karami M, Kasaeian A, Kassaye HG, Kavetskyy T, Kebede HK, Keiyoro PN, Kelbore AG, Kelkay B, Khader YS, Khafaie MA, Khalid N, Khalil IA, Khalilov R, Khammarnia M, Khan EA, Khan M, Khanna T, Khazaie H, Shadmani FK, Khundkar R, Kiirithio DN, Kim YE, Kim D, Kim YJ, Kisa A, Kisa S, Komaki H, M Kondlahalli SK, Korshunov VA, Koyanagi A, G Kraemer MU, Krishan K, Bicer BK, Kugbey N, Kumar V, Kumar N, Kumar GA, Kumar M, Kumaresh G, Kurmi OP, Kuti O, Vecchia C, Lami FH, Lamichhane P, Lang JJ, Lansingh VC, Laryea DO, Lasrado S, Latifi A, Lauriola P, Leasher JL, Huey Lee SW, Lenjebo TL, Levi M, Li S, Linn S, Liu X, Lopez AD, Lotufo PA, Lunevicius R, Lyons RA, Madadin M, El Razek MMA, Mahotra NB, Majdan M, Majeed A, Malagon-Rojas JN, Maled V, Malekzadeh R, Malta DC, Manafi N, Manafi A, Manda AL, Manjunatha N, Mansour-Ghanaei F, Mansouri B, Mansournia MA, Maravilla JC, March LM, Mason-Jones AJ, Masoumi SZ, Massenburg BB, Maulik PK, Meles GG, Melese A, Melketsedik ZA, N Memiah PT, Mendoza W, Menezes RG, Mengesha MB, Mengesha MM, Meretoja TJ, Meretoja A, Merie HE, Mestrovic T, Miazgowski B, Miazgowski T, Miller TR, Mini GK, Mirica A, Mirrakhimov EM, Mirzaei-Alavijeh M, Mithra P, Moazen B, Moghadaszadeh M, Mohamadi E, Mohammad Y, Mohammad KA, Darwesh AM, Gholi Mezerji NM, Mohammadian-Hafshejani A, Mohammadoo-Khorasani M, Mohammadpourhodki R, Mohammed S, Mohammed JA, Mohebi F, Molokhia M, Monasta L, Moodley Y, Moosazadeh M, Moradi M, Moradi G, Moradi-Lakeh M, Moradpour F, Morawska L, Velásquez IM, Morisaki N, Morrison SD, Mossie TB, Muluneh AG, Murthy S, Musa KI, Mustafa G, Nabhan AF, Nagarajan AJ, Naik G, Naimzada MD, Najafi F, Nangia V, Nascimento BR, Naserbakht M, Nayak V, Ndwandwe DE, Negoi I, Ngunjiri JW, Nguyen CT, Thi Nguyen HL, Nikbakhsh R, Anggraini Ningrum DN, Nnaji CA, Nyasulu PS, Ogbo FA, Oghenetega OB, Oh IH, Okunga EW, Olagunju AT, Olagunju TO, Bali AO, Onwujekwe OE, Asante KO, Orpana HM, Ota E, Otstavnov N, Otstavnov SS, A MP, Padubidri JR, Pakhale S, Pakshir K, Panda-Jonas S, Park EK, Patel SK, Pathak A, Pati S, Patton GC, Paulos K, Peden AE, Filipino Pepito VC, Pereira J, Pham HQ, Phillips MR, Pinheiro M, Polibin RV, Polinder S, Poustchi H, Prakash S, Angga Pribadi DR, Puri P, Syed ZQ, Rabiee M, Rabiee N, Radfar A, Rafay A, Rafiee A, Rafiei A, Rahim F, Rahimi S, Rahimi-Movaghar V, Rahman MA, Rajabpour-Sanati A, Rajati F, Rakovac I, Ranganathan K, Rao SJ, Rashedi V, Rastogi P, Rathi P, Rawaf S, Rawal L, Rawassizadeh R, Renjith V, N Renzaho AM, Resnikoff S, Rezapour A, Ribeiro AI, Rickard J, Rios González CM, Ronfani L, Roshandel G, Saad AM, Sabde YD, Sabour S, Saddik B, Safari S, Safari-Faramani R, Safarpour H, Safdarian M, Sajadi SM, Salamati P, Salehi F, Zahabi SS, Rashad Salem MR, Salem H, Salman O, Salz I, Samy AM, Sanabria J, Riera LS, Santric Milicevic MM, Sarker AR, Sarveazad A, Sathian B, Sawhney M, Sawyer SM, Saxena S, Sayyah M, Schwebel DC, Seedat S, Senthilkumaran S, Sepanlou SG, Seyedmousavi S, Sha F, Shaahmadi F, Shahabi S, Shaikh MA, Shams-Beyranvand M, Shamsizadeh M, Sharif-Alhoseini M, Sharifi H, Sheikh A, Shigematsu M, Shin JI, Shiri R, Siabani S, Sigfusdottir ID, Singh PK, Singh JA, Sinha DN, Smarandache CG, R Smith EU, Soheili A, Soleymani B, Soltanian AR, Soriano JB, Sorrie MB, Soyiri IN, Stein DJ, Stokes MA, Sufiyan MB, Rasul Suleria HA, Sykes BL, Tabarés-Seisdedos R, Tabb KM, Taddele BW, Tadesse DB, Tamiru AT, Tarigan IU, Tefera YM, Tehrani-Banihashemi A, Tekle MG, Tekulu GH, Tesema AK, Tesfay BE, Thapar R, Tilahune AB, Tlaye KG, Tohidinik HR, Topor-Madry R, Tran BX, Tran KB, Tripathy JP, Tsai AC, Car LT, Ullah S, Ullah I, Umar M, Unnikrishnan B, Upadhyay E, Uthman OA, Valdez PR, Vasankari TJ, Venketasubramanian N, Violante FS, Vlassov V, Waheed Y, Weldesamuel GT, Werdecker A, Wiangkham T, Wolde HF, Woldeyes DH, Wondafrash DZ, Wondmeneh TG, Wondmieneh AB, Wu AM, Yadav R, Yadollahpour A, Yano Y, Yaya S, Yazdi-Feyzabadi V, Yip P, Yisma E, Yonemoto N, Yoon SJ, Youm Y, Younis MZ, Yousefi Z, Yu Y, Yu C, Yusefzadeh H, Moghadam TZ, Zaidi Z, Zaman SB, Zamani M, Zamanian M, Zandian H, Zarei A, Zare F, Zhang ZJ, Zhang Y, Zodpey S, Dandona L, Dandona R, Degenhardt L, Dharmaratne SD, Hay SI, Mokdad AH, Reiner RC Jr, Sartorius B, and Vos T

Subjects
Humans, Incidence, Life Expectancy, Morbidity, Quality-Adjusted Life Years, Global Burden of Disease, Global Health, Wounds and Injuries mortality
Abstract

Background: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries., Methods: We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs)., Findings: In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505)., Interpretation: Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care., Competing Interests: Competing interests: Dr. James reports grants from Sanofi Pasteur, outside the submitted work. Dr. Driscoll reports grants from World Health Organization, during the conduct of the study. Dr. Ivers reports grants from National Health and Medical Research Council of Australia, during the conduct of the study. Dr. Jozwiak reports personal fees from TEVA, personal fees from ALAB, personal fees from BOEHRINGER INGELHEIM, personal fees from SYNEXUS, non-financial support from SERVIER, non-financial support from MICROLIFE, non-financial support from MEDICOVER, outside the submitted work. Dr. Rakovac reports grants from World Health Organization, during the conduct of the study. Dr Shariful Islam is funded by National Heart Foundation of Australia and Institute for Physical Activity and Nutrition, Deakin University. Dr. Sheikh reports grants from Health Data Research UK, outside the submitted work. Dr. Singh reports personal fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio health, Medscape, WebMD, Clinical Care options, Clearview healthcare partners, Putnam associates, Spherix, Practice Point communications, the National Institutes of Health and the American College of Rheumatology, and Speaker’s bureau of Simply Speaking, owns stock options in Amarin pharmaceuticals and Viking pharmaceuticals, serves on the steering committee of OMERACT, an international organization that develops measures for clinical trials and receives arm’s length funding from 12 pharmaceutical companies, serves on the FDA Arthritis Advisory Committee, is a member of the Veterans Affairs Rheumatology Field Advisory Committee, and is the editor and the Director of the UAB Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis, outside the submitted work. Dr. Stein reports personal fees from Lundbeck, personal fees from Sun, outside the submitted work. Dr. Degenhardt reports grants from Indivior, Seqirus, Reckitt Benckiser, outside the submitted work., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.)

Published
2020
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