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17 results on '"Lempidakis D"'

5. P3728Long non coding RNA levels in hypertensive patients with heart failure with preserved ejection fraction and their relation to their functional capacity

Author

Kontaraki, J, primary, Marketou, M, additional, Maragkoudakis, S, additional, Kochiadakis, G, additional, Konstantinou, J, additional, Daskalakis, A, additional, Vernardos, M, additional, Lempidakis, D, additional, Loulakakis, M, additional, Theodosaki, O, additional, Papadopoulos, D, additional, Vardas, P, additional, and Parthenakis, F, additional

Published
2018
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8. LONG NON CODING RNAS IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN HYPERTENSIVES WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION AND THEIR RELATION TO THEIR FUNCTIONAL CAPACITY

Author

Marketou, M., primary, Kontaraki, J., additional, Kochiadakis, G., additional, Maragkoudakis, S., additional, Vernardos, M., additional, Fragkiadakis, K., additional, Lempidakis, D., additional, Theodosaki, O., additional, Logakis, J., additional, and Parthenakis, F., additional

Published
2018
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9. P6052Long non coding RNA levels in hypertensive patients and their relation to left ventricular hypertrophy

Author

Kontaraki, J., primary, Marketou, M., additional, Parthenakis, F., additional, Kochiadakis, G., additional, Konstantinou, J., additional, Stavroulaki, M., additional, Vernardos, M., additional, Lempidakis, D., additional, Kouvidis, E., additional, Theodosaki, O., additional, Tsiverdis, P., additional, Logakis, J., additional, and Vardas, P., additional

Published
2017
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10. P846Differential platelet alpha2B-adrenergic receptors gene expression levels following coronary stent implantation: the effect of Bioabsorbable Polymer Everolimus-Eluting Synergy stents

Author

Marketou, M., primary, Spanaki, A., additional, Parthenakis, F., additional, Kontaraki, J., additional, Zacharis, E., additional, Lempidakis, D., additional, Mpantouvakis, G., additional, Konstantinou, J., additional, Logakis, J., additional, Vougia, D., additional, Theodosaki, O., additional, Vernardos, M., additional, and Vardas, P., additional

Published
2017
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11. P6053Increased alpha2B-adrenergic receptors gene expression in platelets from patients with not adequately controlled essential hypertension

Author

Marketou, M., primary, Kontaraki, J., additional, Parthenakis, F., additional, Roufas, K., additional, Patrianakos, A., additional, Kochiadakis, G., additional, Tsiverdis, P., additional, Lempidakis, D., additional, Zacharis, E., additional, Fragkiadakis, K., additional, Daskalakis, A., additional, Mpantouvakis, G., additional, and Vardas, P., additional

Published
2017
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12. P2573MicroRNA-21 gene expression levels in peripheral monocytes reflect myocardial damage in acute myocarditis

Author

Marketou, M., primary, Kontaraki, J., additional, Konstantinou, J., additional, Parthenakis, F., additional, Patrianakos, A., additional, Nakou, H., additional, Lempidakis, D., additional, Vernardos, M., additional, Fragkiadakis, K., additional, Loulakakis, M., additional, Stavroulaki, M., additional, Papadopoulos, D., additional, Mpantouvakis, G., additional, Kouvidis, E., additional, and Vardas, P., additional

Published
2017
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13. P2579Differential microRNA gene expression levels in patients with acute myocarditis

Author

Marketou, M., primary, Kontaraki, J., additional, Konstantinou, J., additional, Parthenakis, F., additional, Nakou, H., additional, Lempidakis, D., additional, Vernardos, M., additional, Fragkiadakis, K., additional, Loulakakis, M., additional, Theodosaki, O., additional, Kochiadakis, G., additional, Logakis, J., additional, Vougia, D., additional, and Vardas, P., additional

Published
2017
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14. Injecting a ventricular tachycardia into the heart-Α unique case report.

Author

Kanoupakis EM, Plevritaki A, Koutalas EP, Lazopoulos GL, Patrianakos AP, Foukarakis Ε, Lempidakis D, Kalogerakos PD, Koutentakis D, and Kochiadakis GE

Subjects
Humans, Female, Middle Aged, Arrhythmias, Cardiac, Heart, Bone Cements, Kyphoplasty methods, Tachycardia, Ventricular diagnosis, Tachycardia, Ventricular etiology, Tachycardia, Ventricular surgery
Abstract

Introduction: A 52-year-old woman presented with a complex ventricular arrhythmia in an intraoperative context, during kyphoplasty for an osteoporotic fracture of a lumbar vertebra. The subject showed no indications of a previous cardiovascular condition., Methods and Results: Causes of arrhythmias associated with the procedure were excluded. Due to her positive family history for dilated cardiomyopathy, upcoming thoughts were made for unmasking a previous asymptomatic cardiomyopathy. Nevertheless, an intracardiac cement embolism was diagnosed and, finally, the patient underwent an open-heart surgery with successful removal of the cardiac cement. Νo new arrhythmia recorded during follow up., Conclusion: To the best of our knowledge, this is the first reported case of ventricular arrhythmogenic presentation of a cardiac cement embolus after a KP procedure., (© 2023 Wiley Periodicals LLC.)

Published
2023
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15. Non-typhoidal Salmonella myocarditis in an immunocompetent young adult with diarrhea.

Author

Markaki L, Spernovasilis N, Lempidakis D, Kokorakis E, Gialamas I, Petousis S, Kofteridis D, and Simantirakis E

Subjects
Adult, Humans, Immunocompetence, Male, Myocarditis microbiology, Salmonella Infections microbiology, Diarrhea microbiology, Myocarditis diagnosis, Salmonella Infections diagnosis, Salmonella enterica isolation & purification
Abstract

Myocarditis is the inflammation of the heart muscle and it is caused by a wide range of infectious and non-infectious conditions. Non-typhoidal Salmonella infection, a common foodborne illness worldwide, only rarely causes myocarditis. We describe a case of an immunocompetent adult with Salmonella enterica serovar Typhimurium myocarditis who had a favorable outcome due to early recognition of the causative factor and prompt initiation of appropriate treatment., Competing Interests: The authors declare no competing interests., (© Lamprini Markaki et al.)

Published
2019
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16. Bradykinin receptors gene expression in white adipose tissue in nondiabetic patients with coronary artery disease.

Author

Marketou ME, Kochiadakis G, Kontaraki J, Zacharis E, Kanoupakis E, Kallergis E, Mavrakis H, Tsiverdis P, Lempidakis D, Konstantinou J, Fragkiadakis K, Chlouverakis G, Vardas P, and Parthenakis F

Subjects
Aged, Case-Control Studies, Female, Humans, Male, Middle Aged, RNA, Messenger metabolism, Subcutaneous Fat metabolism, Adipose Tissue, White metabolism, Coronary Artery Disease genetics, Gene Expression, Receptors, Bradykinin genetics
Abstract

Objectives: Adipose tissue plays a key role in cardiovascular physiology. Kinin receptors are important determinant of the effect of adiposity on endothelial function and cardiovascular function. We examined the gene expression levels of kinin receptors in the subcutaneous white adipose tissue (sWAT) of nondiabetic patients with and without coronary artery disease (CAD)., Patients and Methods: We evaluated 21 patients with CAD (13 men, age: 68±8 years) and 23 patients without CAD (15 men, age: 66±5 years) who underwent catheterization through the femoral route. sWAT biopsies were obtained from the site of vessel puncture before the procedure and analyzed for bradykinin receptor type 1 (BKR1) and 2 (BKR2) gene expression by real-time quantitative PCR., Results: Although BKR2 expression levels did not differ significantly (413.12±532.41 in CAD patients vs. 378.33±534.45 in controls, P=NS), BKR1 expression in sWAT was significantly greater in patients with CAD (352.69±455.12 vs. 46.5±46.7, P<0.05). Notably, BKR1 gene expression levels showed a significant positive correlation with BMI (r=0.45, P<0.002) and total cholesterol levels (r=0.53, P<0.001), and a negative correlation with fasting blood glucose (r=-0.4, P=0.006)., Conclusion: There is a divergence in BKR1 gene expression in sWAT between patients with and without CAD and is associated with metabolic parameters. More studies are needed to determine the pathophysiological role of BKRs in adipogenesis, fat expansion, and atheromatous disease.

Published
2018
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17. Increased platelet alpha 2B -adrenergic receptor gene expression in well-controlled hypertensives: the effect of arterial stiffness.

Author

Marketou ME, Kontaraki JE, Papadakis JA, Vrentzos GE, Patrianakos A, Fragkiadakis K, Tsiverdis P, Lempidakis D, Chlouverakis G, Vardas PE, and Parthenakis FI

Subjects
Aged, Blood Pressure physiology, Carotid Arteries physiopathology, Essential Hypertension drug therapy, Female, Femoral Artery physiopathology, Humans, Male, Middle Aged, Pulse Wave Analysis, Radial Artery physiopathology, Real-Time Polymerase Chain Reaction, Blood Platelets metabolism, Essential Hypertension physiopathology, Receptors, Adrenergic, alpha-2 metabolism, Vascular Stiffness physiology
Abstract

Catecholamines play a major role in atherothrombotic mechanisms in essential hypertension. Alpha 2B -adrenergic receptors (α2B-ARs) are implicated in the pathophysiology of platelet aggregation. In this study, we evaluated platelet α2B-AR gene expression levels in patients with well-controlled essential hypertension compared with normal individuals and investigated their association with increased arterial stiffness. Fifty-nine patients with well-controlled essential hypertension (34 men, mean age 65 ± 9 years) and 26 normotensives (19 men, mean age 64 ± 8 years) were included in the study. For each patient, carotid-femoral pulse wave velocity (PWV) and carotid-radial PWV were evaluated. In addition, blood samples were obtained and platelets were isolated. The α2B-AR gene expression levels in platelets were examined by real-time polymerase chain reaction for each participant. Well-controlled hypertensive patients showed significantly higher gene expression levels of α2B-Rs in platelets compared with normotensives (34.7 ± 29.5 vs 17.6 ± 12.5, respectively, P = .005). Interestingly, we found that carotid-femoral PWV and carotid-radial PWV were positively correlated with platelet α2B-R gene expression levels (r = 0.59, P < .001, and r = 0.39, P = .002, respectively).Platelet α2B-R gene expression levels are increased in patients with well-controlled essential hypertension compared with normotensives and are correlated with increased PWV in those patients. Our data indicate an association of arterial stiffness and platelet α2B-Rs gene expression and indicate the need for further research., (Copyright © 2017 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.)

Published
2017
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