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1. Brucellosis presenting as piriformis myositis: a case report

Author

Romanos Odysseas, Lekkou Alexandra, Marangos Markos, Kraniotis Pantelis, and Solomou Ekaterini

Subjects
Medicine
Abstract

Abstract Introduction Myositis is a rare bacterial muscle infection. Involvement of the piriformis muscle has been rarely reported in the literature. In this report we describe a case of piriformis myositis due to Brucella melitensis, which to the best of our knowledge is the first such case presented in the literature. Case presentation We report the case of a 19-year-old Caucasian man who presented to our institution with fever and right hip pain. Brucellosis was suspected, but the clinical suspicion was for spondylodiscitis. A pelvic magnetic resonance imaging scan allowed prompt diagnosis of inflammatory involvement of the right piriformis muscle. Blood culture results were positive for B. melitensis. Our patient was treated with antibiotics, and follow-up magnetic resonance imaging scans showed resolution of the inflammation. Conclusion Brucellosis can present as piriformis myositis. The clinical diagnosis of piriformis myositis is difficult, as it can mimic other common entities such as referred back pain from spondylodiscitis. Magnetic resonance imaging is the method of choice for establishing the diagnosis in the early stages of the disease, as late diagnosis can lead to abscess formation and the need for drainage.

Published
2011
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3. Prevalence of Hepatitis D in People Living with HIV: A National Cross-Sectional Pilot Study

Author

Georgios Schinas, Nikolina Antonopoulou, Sofia Vamvakopoulou, Olga Tsachouridou, Konstantinos Protopapas, Vasileios Petrakis, Emmanouil C. Petrakis, Despoina Papageorgiou, Simeon Metallidis, Antonios Papadopoulos, Emmanouil Barbounakis, Diamantis Kofteridis, Periklis Panagopoulos, Alexandra Lekkou, Fotini Paliogianni, and Karolina Akinosoglou

Subjects
hepatitis D, HIV infections, hepatitis B, coinfection, Greece, epidemiological monitoring, Microbiology, QR1-502
Abstract

This study assesses the prevalence of hepatitis D virus (HDV) in people living with HIV (PLWHIV) in Greece. Given the compounding effects of HDV and hepatitis B (HBV) on liver disease progression, as well as the emergence of new therapeutic options such as bulevirtide, understanding regional disparities and the epidemiological impact of such co-infections is vital. A cross-sectional analysis was conducted utilizing 696 serum samples from PLWHIV attending five major university hospitals. The methodology included HDV antibody detection by ELISA and HDV RNA confirmation. Of the 30 HBsAg-positive samples analyzed, the study population was primarily male (93%), with a median age of 54 years. Participants had been on antiretroviral therapy for a median of 10 years, and the median CD4 count was 738 (539–1006) copies/mL. Additional serological findings revealed a 7% prevalence of hepatitis C virus (HCV) IgG antibodies and a 55% prevalence of hepatitis A virus (HAV) IgG antibodies. Seroreactivity for syphilis (RPR/VDRL/TPHA positive) was identified in 33% of the participants. The results indicated a low HDV prevalence, with only one individual (3%) testing positive for anti-HDV IgG antibodies and none for HDV RNA. This indicates a lower prevalence of HDV among PLWHIV with chronic HBV in Greece compared to global data.

Published
2024
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4. Acremonium nail bed mycetoma masquerading as subungual squamous cell carcinoma

Author

Kyriakou, Georgia, Gialeli, Efthymia, Lekkou, Alexandra, Vryzaki, Eleftheria, Ravazoula, Panagiota, and Georgiou, Sophia

Subjects
Acremonium, mycology, nails, malformed, mycetoma
Abstract

Acremonium is a large fungal genus that is comprised of approximately 150 species, found ubiquitously in nature. Although the majority are recognized as being saprophytes in soil and pathogens of plants, several species are emerging as causative agents of a variety of human infections, including mycetomas. Herein, we present a young man that was referred to our department with a painful subungual mass that developed following traumatic inoculation of Acremonium spp. In recent years, the role of Acremonium spp. has been increasingly recognized in localized infections, such as mycetoma, in humans. Other locally invasive as well as disseminated infections are also described. Optimal treatment of Acremonium spp. mycetoma is not well defined owing to the rarity of cases, thus posing a therapeutic challenge.

Published
2020

5. Tears evoke the intention to offer social support: A systematic investigation of the interpersonal effects of emotional crying across 41 countries

Author

Zickfeld, Janis H., van de Ven, Niels, Pich, Olivia, Schubert, Thomas W., Berkessel, Jana B., Pizarro, José J., Bhushan, Braj, Mateo, Nino Jose, Barbosa, Sergio, Sharman, Leah, Kökönyei, Gyöngyi, Schrover, Elke, Kardum, Igor, Aruta, John Jamir Benzon, Lazarevic, Ljiljana B., Escobar, María Josefina, Stadel, Marie, Arriaga, Patrícia, Dodaj, Arta, Shankland, Rebecca, Majeed, Nadyanna M., Li, Yansong, Lekkou, Eleimonitria, Hartanto, Andree, Özdoğru, Asil A., Vaughn, Leigh Ann, del Carmen Espinoza, Maria, Caballero, Amparo, Kolen, Anouk, Karsten, Julie, Manley, Harry, Maeura, Nao, Eşkisu, Mustafa, Shani, Yaniv, Chittham, Phakkanun, Ferreira, Diogo, Bavolar, Jozef, Konova, Irina, Sato, Wataru, Morvinski, Coby, Carrera, Pilar, Villar, Sergio, Ibanez, Agustin, Hareli, Shlomo, Garcia, Adolfo M., Kremer, Inbal, Götz, Friedrich M., Schwerdtfeger, Andreas, Estrada-Mejia, Catalina, Nakayama, Masataka, Ng, Wee Qin, Sesar, Kristina, Orjiakor, Charles T., Dumont, Kitty, Allred, Tara Bulut, Gračanin, Asmir, Rentfrow, Peter J., Schönefeld, Victoria, Vally, Zahir, Barzykowski, Krystian, Peltola, Henna-Riikka, Tcherkassof, Anna, Haque, Shamsul, Śmieja, Magdalena, Su-May, Terri Tan, IJzerman, Hans, Vatakis, Argiro, Ong, Chew Wei, Choi, Eunsoo, Schorch, Sebastian L., Páez, Darío, Malik, Sadia, Kačmár, Pavol, Bobowik, Magdalena, Jose, Paul, Vuoskoski, Jonna K., Basabe, Nekane, Doğan, Uğur, Ebert, Tobias, Uchida, Yukiko, Zheng, Michelle Xue, Mefoh, Philip, Šebeňa, René, Stanke, Franziska A., Ballada, Christine Joy, Blaut, Agata, Wu, Yang, Daniels, Judith K., Kocsel, Natália, Burak, Elif Gizem Demirag, Balt, Nina F., Vanman, Eric, Stewart, Suzanne L.K., Verschuere, Bruno, Sikka, Pilleriin, Boudesseul, Jordane, Martins, Diogo, Nussinson, Ravit, Ito, Kenichi, Mentser, Sari, Çolak, Tuğba Seda, Martinez-Zelaya, Gonzalo, and Vingerhoets, Ad

Published
2021
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6. Evolution of epidemiological characteristics of infective endocarditis in Greece

Author

Pontikis, Konstantinos, Lioris, Ioannis, Lelekis, Moysis, Trikkas, Athanasios, Aggouras, Dimitrios, Kolias, Vasilios, Rokkas, Chris, Nana-Anastasiou, Maria, Miyakis, Spiros, Giannitsioti, Efthymia, Pefanis, Angelos, Gogos, Charalampos, Lekkou, Alexandra, Dalekos, Georgios N., Gatselis, Nikolaos, Georgiadou, Sara, Nikou, Paraskevas, Vrettou, Agathi, Rigopoulos, Angelos, Tryfonopoulos, Christos, Tsaganos, Thomas, Karofilakis, Emmanouil, Psarrakis, Christos, Argyriou, Michail, Gargalianos-Kakolyris, Panagiotis, Adamis, Georgios, Lourida, Panagiota, Kofteridis, Diamantis, Andrianaki, Aggeliki, Loupa, Chariclia, Kostis, Evangelos, Sinapidis, Dimitris, Sympardi, Styliani, Alexiou, Nikolaos, Karaiskos, Ilias, Masgala, Aikaterini, Maltezos, Efstratios, Panagopoulos, Periklis, Sachpekidis, Vasileios, Evdoridis, Constantinos, Sipsas, Nikolaos V., Daikos, Georgios, and Giamarellou, Helen

Published
2021
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7. Prevalence of Hepatitis D in People Living with HIV: A National Cross-Sectional Pilot Study.

Author

Schinas, Georgios, Antonopoulou, Nikolina, Vamvakopoulou, Sofia, Tsachouridou, Olga, Protopapas, Konstantinos, Petrakis, Vasileios, Petrakis, Emmanouil C., Papageorgiou, Despoina, Metallidis, Simeon, Papadopoulos, Antonios, Barbounakis, Emmanouil, Kofteridis, Diamantis, Panagopoulos, Periklis, Lekkou, Alexandra, Paliogianni, Fotini, and Akinosoglou, Karolina

Subjects
HEPATITIS D virus, HEPATITIS D, HEPATITIS C virus, HEPATITIS viruses, VIRAL hepatitis
Abstract

This study assesses the prevalence of hepatitis D virus (HDV) in people living with HIV (PLWHIV) in Greece. Given the compounding effects of HDV and hepatitis B (HBV) on liver disease progression, as well as the emergence of new therapeutic options such as bulevirtide, understanding regional disparities and the epidemiological impact of such co-infections is vital. A cross-sectional analysis was conducted utilizing 696 serum samples from PLWHIV attending five major university hospitals. The methodology included HDV antibody detection by ELISA and HDV RNA confirmation. Of the 30 HBsAg-positive samples analyzed, the study population was primarily male (93%), with a median age of 54 years. Participants had been on antiretroviral therapy for a median of 10 years, and the median CD4 count was 738 (539–1006) copies/mL. Additional serological findings revealed a 7% prevalence of hepatitis C virus (HCV) IgG antibodies and a 55% prevalence of hepatitis A virus (HAV) IgG antibodies. Seroreactivity for syphilis (RPR/VDRL/TPHA positive) was identified in 33% of the participants. The results indicated a low HDV prevalence, with only one individual (3%) testing positive for anti-HDV IgG antibodies and none for HDV RNA. This indicates a lower prevalence of HDV among PLWHIV with chronic HBV in Greece compared to global data. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Bacillus simplex as the Most Probable Culprit of Penetrating Trauma Infection: A Case Report

Author

Panagiota Xaplanteri, Dimitrios S. Serpanos, Ellie Dorva, Tatiana Beqo-Rokaj, Eleni Papadogeorgaki, and Alexandra Lekkou

Subjects
Bacillus simplex, penetrating trauma, infection, Medicine
Abstract

Bacillus simplex is an environmental microorganism found in soil. Herein, we present the case of a 69-year-old Greek male patient who attended the Emergency Department at our hospital. The patient complained of lower right extremity swelling and pain, after suffering penetrating trauma whilst doing farm work in a rural area. Swab aerobic cultures revealed Bacillus simplex as identified by MALDI-TOF Mass Spectrometry. The strain was susceptible to vancomycin, imipenem, clindamycin, and ciprofloxacin. Our patient refused hospitalization; therefore, both ciprofloxacin and clindamycin were registered for a total of 19 days. No complications were experienced, and he recovered fully. In our case, the thorough cleaning of the ulcer bed prior to sample collection, the fact that it was the only microorganism isolated, and the wound’s aggravating mechanism led the authors of the present study to the conclusion that B. simplex was the most probable culprit of the infection. To our knowledge, this is the second probable case of B. simplex infection described worldwide, and the first in Greece.

Published
2022
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9. Study on the Interaction between Serum Thyrotropin and Semen Parameters in Men

Author

Ioannis Kakoulidis, Ioannis Ilias, Stefanos Stergiotis, Stefanos Togias, Aikaterini Michou, Anastasia Lekkou, Vasiliki Mastrodimou, Athina Pappa, Charalampos Milionis, Evangelia Venaki, and Eftychia Koukkou

Subjects
male, human, semen analysis, thyroid, thyrotropin, Medicine
Abstract

The effect of thyroid function on semen parameters has been studied in pathological conditions in small studies. With this research work, we aimed to study thyroid hormone effects on semen parameters in 130 men who were evaluated for couple subfertility. Our study was cross-sectional. We noted semen volume, sperm concentration, total sperm count, testosterone levels and thyrotropin (TSH) levels. The analysis included ordinary least squares regression (OLS-R), quantile regression (QR) and segmented line regression (SR). Using OLS-R, a weak negative correlation was found between the logTSH levels and semen volume (r = −0.16, r2 = 0.03, p = 0.05). In Q-R, each incremental unit increase in logTSH decreased the mean semen volume between −0.78 ± 0.44 and −1.33 ± 0.34 mL (40–60th response quantile) and between −1.19 ± 0.71 and −0.61 ± 0.31 mL (70–90th response quantile) (p = 0.049). With SR, a biphasic relationship of sperm concentration with TSH was noted (positive turning to negative, peaking at TSH = 1.22 μIU/mL). Thus, a weak negative association between the TSH levels and semen volume was noted, showing a trough within the usual normal range for TSH. Moreover, a biphasic relationship between the sperm concentration and TSH was also noted, peaking at approximately mid-normal TSH levels. Based on our results, TSH explained slightly less than 3% of the variation in semen volume and 7% of the sperm concentration (thus, other factors, which were not studied here, have a more important effect on it).

Published
2022
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10. Late PAMM-Like Lesions in a Patient with HIV Retinopathy

Author

Menelaos Kanakis, Ilias Georgalas, Vassilios Kozobolis, Alexandra Lekkou, Efthymios Karmiris, and Panagiotis Stavrakas

Subjects
Ophthalmology
Abstract

This report describes a case of a newly diagnosed 49-year-old HIV patient, who presented with decreased visual acuity and retinal lesions characterized by ischemia at the level of the deep retinal capillary plexus, documented with optical coherence tomography (OCT), OCT angiography, fluorescein angiography, and visual fields testing. These lesions closely resembled the morphologic and clinical characteristics of late paracentral acute middle maculopathy. The presence of these lesions suggests that HIV microangiopathy can potentially affect both superficial and deep retinal capillary plexuses.

Published
2023
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11. Unveiling the Hidden Perils: A Comprehensive Review of Fungal Infections in Inflatable Penile Prosthesis Surgery.

Author

Natsos, Anastasios, Tatanis, Vasileios, Lekkou, Alexandra, Kontogiannis, Stavros, Vagionis, Athanasios, Spinos, Theodoros, Peteinaris, Angelis, Obaidat, Mohammed, Pagonis, Konstantinos, Kallidonis, Panagiotis, Liatsikos, Evangelos, and Drettas, Petros

Subjects
MYCOSES, PENILE prostheses, THERAPEUTIC touch, IMPOTENCE, SYMPTOMS, ANTIFUNGAL agents, DIABETES, SURGERY
Abstract

Inflatable penile prosthesis (IPP) surgery is an effective treatment for erectile dysfunction (ED), but infections pose a significant threat to its success. Current guidelines lack antifungal recommendations, despite rising fungal infection rates post-IPP surgery. This review examines epidemiology, risk factors (including diabetes mellitus, immunosuppression, and obesity), and pathogenesis, highlighting the role of biofilm formation in device contamination. Clinical manifestations vary from acute to delayed, with fungal biofilms presenting challenges in diagnosis. Prophylactic strategies, including broad-spectrum antibiotics and antifungals, are crucial, with evidence suggesting a 92% reduction in infections. With fungal infections showing lower salvage rates, management involves culture-guided treatment, irrigation, and oral antibiotics. Future research aims to understand biofilm mechanisms and develop biomaterials to reduce infection rates. Implementing antifungal therapy, along with standard practices like the no-touch technique and antibiotic dips, is crucial in preventing IPP infections. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Late PAMM-Like Lesions in a Patient with HIV Retinopathy

Author

Kanakis, M. Georgalas, I. Kozobolis, V. Lekkou, A. Karmiris, E. Stavrakas, P. and Kanakis, M. Georgalas, I. Kozobolis, V. Lekkou, A. Karmiris, E. Stavrakas, P.

Abstract

This report describes a case of a newly diagnosed 49-year-old HIV patient, who presented with decreased visual acuity and retinal lesions characterized by ischemia at the level of the deep retinal capillary plexus, documented with optical coherence tomography (OCT), OCT angiography, fluorescein angiography, and visual fields testing. These lesions closely resembled the morphologic and clinical characteristics of late paracentral acute middle maculopathy. The presence of these lesions suggests that HIV microangiopathy can potentially affect both superficial and deep retinal capillary plexuses. © 2023 Authors. All rights reserved.

Published
2023

14. Fungemia due to rare non-Candida yeasts between 2018 and 2021 in a Greek tertiary care university hospital

Author

Spiliopoulou, A. Lekkou, A. Vrioni, G. Leonidou, L. Cogliati, M. Christofidou, M. Marangos, M. Kolonitsiou, F. Paliogianni, F. and Spiliopoulou, A. Lekkou, A. Vrioni, G. Leonidou, L. Cogliati, M. Christofidou, M. Marangos, M. Kolonitsiou, F. Paliogianni, F.

Abstract

Introduction: Non-Candida yeasts, although rare, are increasingly encountered and recognized as a growing threat. Methods: Cases of bloodstream infections (BSIs) due to non-Candida yeasts (NCYs) during the last four years (2018–2021) are presented. Results: During the study period, 16 cases caused by non-Candida yeasts out of 400 cases of yeast BSIs were recorded, corresponding to an incidence of 4%. Yeasts that were isolated included Cryptococcus spp (4 isolates-25%), Rhodotorula mucilaginosa (2 isolates-12.5%), Trichosporon asahii (7 isolates-43.75%) and Saccharomyces cerevisiae (3 isolates-18.75%). Predisposing factors involved mostly hematological malignancies, long term hospitalization or major surgical interventions. Most isolates, 15 out of 16 were susceptible to amphotericin B. Voriconazole was the most active azole in vitro. All isolates, except Saccharomyces spp., were resistant to echinocandins. Discussion: Early recognition of rare yeasts as causative agents of BSIs and prompt initiation of appropriate treatment based on current guidelines and expertise remain crucial in efficient patient management. © 2023 SFMM

Published
2023

15. Neisseria meningitidis presenting as acute abdomen and recurrent reactive pericarditis

Author

Karolina Akinosoglou, Angelos Alexopoulos, Nikolaos Koutsogiannis, Charalampos Gogos, and Aleksandra Lekkou

Subjects
Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Meningococcal meningitis is a well established potential fatal infection characterized by fever, headache, petechial rash, and vomiting in the majority of cases. However, protean manifestations including abdominal pain, sore throat, diarrhea and cough, even though rare, should not be overlooked. Similarly, although disseminated infection could potentially involve various organ-targets, secondary immune related complications including joints or pericardium should be dealt with caution, since they remain unresponsive to appropriate antibiotic regimens. We hereby report the rare case of an otherwise healthy adult female, presenting with acute abdominal pain masking Neisseria meningitidis serotype B meningitis, later complicated with recurrent reactive pericarditis despite appropriate antibiotic treatment. There follows a review of current literature. Keywords: Reactive pericarditis, Neisseria meningitidis, Meningococcal meningitis

Published
2016
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16. A Case of Serratia marcescens Endocarditis in a Nonintravenous Drug-Using Male Patient and Review of Literature

Author

Achilleas Nikolakopoulos, Nikolaos Koutsogiannis, Panagiota Xaplanteri, Charalambos Gogos, Fevronia Kolonitsiou, and Alexandra Lekkou

Subjects
Infectious and parasitic diseases, RC109-216
Abstract

Introduction. Serratia marcescens is a rare cause of infective endocarditis and has almost exclusively been associated with intravenous drug use and hospital-acquired infections. Here, we present a case of infective endocarditis caused by Serratia marcescens in an otherwise healthy, nonintravenous drug-using male patient. Case Report. A 41-year-old man presented with hypertension and hemoptysis. Blood cultures were obtained that showed bacteremia by Serratia marcescens. An echocardiogram was carried out that revealed severe mitral regurgitation accompanying ruptured mitral chordae tendineae. The patient received the appropriate antibiotic treatment, without further surgical intervention. Discussion. Hospital-acquired infections by Serratia species are a common problem in medical practice and have been attributed to specialized interventional procedures. Taking into consideration the patient’s immunocompetence and lack of intravenous drug use, it is possible that bacteremia could be attributed to a medical procedure. Moreover, in contrast to most cases described in the literature, no surgery was performed.

Published
2019
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17. Atmospheric Pollution and Thyroid Function of Pregnant Women in Athens, Greece: A Pilot Study

Author

Ioannis Ilias, Ioannis Kakoulidis, Stefanos Togias, Stefanos Stergiotis, Aikaterini Michou, Anastasia Lekkou, Vasiliki Mastrodimou, Athina Pappa, Evangelia Venaki, and Eftychia Koukkou

Subjects
pregnancy, thyrotropin, environmental air pollutants, Medicine
Abstract

Exposure to air pollution and, in particular, to nitrogen dioxide (NO2) or particulate pollutants less than 2.5 μm (PM2.5) or 10 μm (PM10) in diameter has been linked to thyroid (dys)function in pregnant women. We hypothesized that there may be a dose—effect relationship between air pollutants and thyroid function parameters. We retrospectively evaluated thyrotropin (TSH) in 293 women, NO2, PM2.5 and PM10 levels in Athens. All the women were diagnosed with hypothyroidism for the first time during their pregnancy. Exposure to air pollution for each woman was considered according to her place of residence. Statistical analysis of age, pregnancy weight change, and air pollutants versus TSH was performed with ordinary least squares regression (OLS-R) and quantile regression (Q-R). A positive correlation for logTSH and PM2.5(r = +0.13, p = 0.02) was found, using OLS-R. Further analysis with Q-R showed that each incremental unit increase (for the 10th to the 90th response quantile) in PM2.5 increased logTSH(±SE) between +0.029 (0.001) to +0.025 (0.001) mIU/L (p < 0.01). The other parameters and pollutants (PM10 and NO2) had no significant effect on TSH. Our results indeed show a dose—response relationship between PM2.5 and TSH. The mechanisms involved in the pathophysiological effects of atmospheric pollutants, in particular PM2.5, are being investigated.

Published
2020
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18. Acid-fast bacteria as causative agents of skin and soft tissue infections: case presentations and literature review

Author

Anastasia Spiliopoulou, Georgia Kyriakou, Sophia Georgiou, Alexandra Lekkou, Lydia Leonidou, Maria Militsopoulou, Eleni Papadogeorgaki, Myrto Christofidou, Fevronia Kolonitsiou, and Fotini Paliogianni

Subjects
Acid-fast bacteria, Skin and soft tissue infections, Mycobacterium marinum, Nocardia brasiliensis, MALDI-TOF MS, Ziehl–Neelsen stain
Abstract

Acid-fast bacteria can be implicated in skin and soft tissue infections. Diagnostic identification can be challenging or not feasible by routine laboratory techniques, especially if there is no access to the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) technology. Here, we present two cases of skin and soft tissue infections caused by two different acid-fast bacteria, Nocardia brasiliensis and Mycobacterium marinum. They both grew on Löwenstein–Jensen medium, Sabouraud agar medium and blood agar medium. Both bacteria appeared acid-fast by Ziehl–Neelsen stain and Gram-positive by Gram stain. The identification was performed by MALDI-TOF MS and gene analysis. N. brasiliensis and nontuberculous mycobacterium M. marinum represent rare pathogens that cause severe skin and soft tissue infections. Failure to identify the causative agent and subsequent inappropriate or inadequate treatment may lead to severe complications or even disseminated disease, especially in immunocompromised individuals.

Published
2023
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22. Treatment of Prosthetic Joint Infection due to ListeriaMonocytogenes. A Comprehensive Literature Review and a Case of Total Hip Arthroplasty Infection

Author

Vasileios Athanasiou, Leonidia Leonidou, Alexandra Lekkou, Panagiotis Antzoulas, Konstantina Solou, Georgios Diamantakis, and John Gliatis

Subjects
Orthopedic surgery, Prosthetic joint infection, THA infection due to Listeria, TKA infection due to Listeria, Orthopedics and Sports Medicine, Surgery, Case Report, Listeria monocytogenes, RD701-811
Abstract

As reported in contemporary literature, prosthetic joint infection (PJI) caused by Listeria monocytogenes (LM) is a rare infection affecting mainly immunocompromised patients. It is considered a late complication occurring months or years after the arthroplasty that is treated with, or without, implant retention, in one-stage or two-stage surgical procedures, and long-term administration of antibiotics. We reviewed the published studies in the English language and present a case of a patient who underwent total hip arthroplasty (THA) and had been affected by this infection. Our patient was successfully treated with 3 months of antibiotics (ampicillin and TMP/SMX) and a two-stage surgical procedure. The success rates of conservative treatment and one-stage or two-stage procedures are dependent on appropriate patient selection and chronicity of the infection. Ιmmmunocompromised patients are susceptible to PJI caused by LM and should be advised that consumption of unpasteurized dairy products increases the risk of this atypical infection.

Published
2021

23. Infective Endocarditis in a Young Adult due to Lactococcus lactis: A Case Report and Review of the Literature

Author

G. Georgountzos, C. Michopoulos, C. Grivokostopoulos, M. Kolosaka, N. Vlassopoulou, and A. Lekkou

Subjects
Medicine
Abstract

Infective endocarditis (IE) is a condition mainly associated with valvular disease or prosthetic valve and intravenous drug use as a risk factor. Here, we describe a rare case of a previously healthy patient with endocarditis due to Lactococcus lactis associated with cattle contact, where antibiotic treatment resulted in full recovery.

Published
2018
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27. A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Author

IJzerman, Hans, Ropovik, Ivan, Ebersole, Charles, Tidwell, Natasha, Markiewicz, Łukasz, de Lima, Tiago Jessé Souza, Wolf, Daniel, Novak, Sarah, Collins, W. Matthew, Menon, Madhavi, de Souza, Luana Elayne Cunha, Sawicki, Przemysław, Boucher, Leanne, Białek, Michał, Idzikowska, Katarzyna, Razza, Timothy, Kraus, Sue, Weissgerber, Sophia, Baník, Gabriel, Kołodziej, Sabina, Babincak, Peter, Schütz, Astrid, Sternglanz, R. Weylin, Gawryluk, Katarzyna, Sullivan, Gavin Brent, Day, Chris, Sparacio, Alessandro, Tops, Mattie, Quirin, Markus, Lewis, Neil, Przybylski, Andrew, Weinstein, Netta, DeBruine, Lisa, Ritchie, Stuart, Vazire, Simine, Forscher, Patrick, Morey, Richard, Ivory, James, Anvari, Farid, Jones, Benedict, Flake, Jessica, Liuzza, Marco Tullio, Antfolk, Jan, Arinze, Nwadiogo, Ndukaihe, Izuchukwu, Bloxsom, Nicholas, Lewis, Savannah, Foroni, Francesco, Willis, Megan, Cubillas, Carmelo, Vadillo, Miguel, Turiegano, Enrique, Gilead, Michael, Simchon, Almog, Saribay, S. Adil, Owsley, Nicholas, Jang, Chaning, Mburu, Georgina, Calvillo, Dustin, Wlodarczyk, Anna, Qi, Yue, Ariyabuddhiphongs, Kris, Jarukasemthawee, Somboon, Manley, Harry, Suavansri, Panita, Taephant, Nattasuda, Stolier, Ryan, Evans, Thomas, Bonick, Judson, Lindemans, Jan, Ashworth, Logan, Hahn, Amanda, Chevallier, Coralie, Kapucu, Aycan, Karaaslan, Aslan, Leongómez, Juan David, Sánchez, Oscar, Valderrama, Eugenio, Vásquez-Amézquita, Milena, Hajdu, Nandor, Aczel, Balazs, Szecsi, Peter, Andreychik, Michael, Musser, Erica, Batres, Carlota, Hu, Chuan-Peng, Liu, Qing-Lan, Legate, Nicole, Vaughn, Leigh Ann, Barzykowski, Krystian, Golik, Karolina, Schmid, Irina, Stieger, Stefan, Artner, Richard, Mues, Chiel, Vanpaemel, Wolf, Jiang, Zhongqing, Wu, Qi, Marcu, Gabriela, Stephen, Ian, Lu, Jackson, Philipp, Michael, Arnal, Jack, Hehman, Eric, Xie, Sally, Chopik, William, Seehuus, Martin, Azouaghe, Soufian, Belhaj, Abdelkarim, Elouafa, Jamal, Wilson, John, Kruse, Elliott, Papadatou-Pastou, Marietta, De La Rosa-Gómez, Anabel, Barba-Sánchez, Alan, González-Santoyo, Isaac, Hsu, Tsuyueh, Kung, Chun-Chia, Wang, Hsiao-Hsin, Freeman, Jonathan, Oh, Dong Won, Schei, Vidar, Sverdrup, Therese, Levitan, Carmel, Cook, Corey, Chandel, Priyanka, Kujur, Pratibha, Parganiha, Arti, Parveen, Noorshama, Pati, Atanu Kumar, Pradhan, Sraddha, Singh, Margaret, Pande, Babita, Bavolar, Jozef, Kačmár, Pavol, Zakharov, Ilya, Álvarez-Solas, Sara, Baskin, Ernest, Thirkettle, Martin, Schmidt, Kathleen, Christopherson, Cody, Leonis, Trinity, Suchow, Jordan, Olofsson, Jonas, Jernsäther, Teodor, Lee, Ai-Suan, Beaudry, Jennifer, Gogan, Taylor, Oldmeadow, Julian, Balas, Benjamin, Stevens, Laura, Colloff, Melissa, Flowe, Heather, Gülgöz, Sami, Brandt, Mark, Hoyer, Karlijn, Jaeger, Bastian, Ren, Dongning, Sleegers, Willem, Wissink, Joeri, Kaminski, Gwenaël, Floerke, Victoria, Urry, Heather, Chen, Sau-Chin, Pfuhl, Gerit, Vally, Zahir, Basnight-Brown, Dana, Jzerman, Hans, Sarda, Elisa, Neyroud, Lison, Badidi, Touhami, Van der Linden, Nicolas, Tan, Chrystalle, Kovic, Vanja, Sampaio, Waldir, Ferreira, Paulo, Santos, Diana, Burin, Debora, Gardiner, Gwendolyn, Protzko, John, Schild, Christoph, Ścigała, Karolina, Zettler, Ingo, O’Mara Kunz, Erin, Storage, Daniel, Wagemans, Fieke, Saunders, Blair, Sirota, Miroslav, Sloane, Guyan, Lima, Tiago, Uittenhove, Kim, Vergauwe, Evie, Jaworska, Katarzyna, Stern, Julia, Ask, Karl, van Zyl, Casper, Körner, Anita, Boudesseul, Jordane, Ruiz-Dodobara, Fernando, Ritchie, Kay, Michalak, Nicholas, Blake, Khandis, White, David, Gordon-Finlayson, Alasdair, Anne, Michele, Janssen, Steve, Lee, Kean Mun, Nielsen, Tonje, Tamnes, Christian, Zickfeld, Janis, Rosa, Anna Dalla, Vianello, Michelangelo, Kocsor, Ferenc, Kozma, Luca, Putz, Ádám, Tressoldi, Patrizio, Irrazabal, Natalia, Chatard, Armand, Lins, Samuel, Pinto, Isabel, Lutz, Johannes, Adamkovic, Matus, Coetzee, Vinet, Dixson, Barnaby, Ribeiro, Gianni, Peters, Kim, Steffens, Niklas, Tan, Kok Wei, Thorstenson, Christopher, Fernandez, Ana Maria, Hsu, Rafael, Valentova, Jaroslava, Varella, Marco, Corral-Frías, Nadia, Frías-Armenta, Martha, Hatami, Javad, Monajem, Arash, Sharifian, MohammadHasan, Frohlich, Brooke, Lin, Hause, Inzlicht, Michael, Alaei, Ravin, Rule, Nicholas, Lamm, Claus, Pronizius, Ekaterina, Voracek, Martin, Olsen, Jerome, Giolla, Erik Mac, Akgoz, Aysegul, Özdoğru, Asil, Crawford, Matthew, Bennett-Day, Brooke, Koehn, Monica, Okan, Ceylan, Gill, Tripat, Miller, Jeremy, Dunham, Yarrow, Yang, Xin, Alper, Sinan, Borras-Guevara, Martha Lucia, Cai, Sun Jun, Tiantian, Dong, Danvers, Alexander, Feinberg, David, Armstrong, Marie, Gilboa-Schechtman, Eva, McCarthy, Randy, Muñoz-Reyes, Jose Antonio, Polo, Pablo, Shiramazu, Victor, Yan, Wen-Jing, Carvalho, Lilian, Chartier, Christopher, Coles, Nicholas, Klein, Richard, Dujols, Olivier, van de Ven, Niels, Pich, Olivia, Schubert, Thomas, Berkessel, Jana, Pizarro, José, Bhushan, Braj, Mateo, Nino Jose, Barbosa, Sergio, Sharman, Leah, Kökönyei, Gyöngyi, Schrover, Elke, Kardum, Igor, Aruta, John Jamir Benzon, Lazarevic, Ljiljana, Escobar, María Josefina, Stadel, Marie, Arriaga, Patrícia, Dodaj, Arta, Shankland, Rebecca, Majeed, Nadyanna, Li, Yansong, Lekkou, Eleimonitria, Hartanto, Andree, del Carmen Espinoza, Maria, Caballero, Amparo, Kolen, Anouk, Karsten, Julie, Maeura, Nao, Eşkisu, Mustafa, Shani, Yaniv, Chittham, Phakkanun, Ferreira, Diogo, Konova, Irina, Sato, Wataru, Morvinski, Coby, Carrera, Pilar, Villar, Sergio, Ibanez, Agustin, Hareli, Shlomo, Garcia, Adolfo, Kremer, Inbal, Götz, Friedrich, Schwerdtfeger, Andreas, Estrada-Mejia, Catalina, Nakayama, Masataka, Ng, Wee Qin, Sesar, Kristina, Orjiakor, Charles, Dumont, Kitty, Allred, Tara Bulut, Gračanin, Asmir, Rentfrow, Peter, Schönefeld, Victoria, Peltola, Henna-Riikka, Tcherkassof, Anna, Haque, Shamsul, Śmieja, Magdalena, Su-May, Terri Tan, Vatakis, Argiro, Ong, Chew Wei, Choi, Eunsoo, Schorch, Sebastian, Páez, Darío, Malik, Sadia, Bobowik, Magdalena, Jose, Paul, Vuoskoski, Jonna, Basabe, Nekane, Doğan, Uğur, Ebert, Tobias, Uchida, Yukiko, Zheng, Michelle Xue, Mefoh, Philip, Šebeňa, René, Stanke, Franziska, Ballada, Christine Joy, Blaut, Agata, Wu, Yang, Daniels, Judith, Kocsel, Natália, Burak, Elif Gizem Demirag, Balt, Nina, Vanman, Eric, Stewart, Suzanne L.K., Verschuere, Bruno, Sikka, Pilleriin, Martins, Diogo, Nussinson, Ravit, Ito, Kenichi, Mentser, Sari, Çolak, Tuğba Seda, Martinez-Zelaya, Gonzalo, Vingerhoets, Ad, Wang, Ke, Goldenberg, Amit, Dorison, Charles, Uusberg, Andero, Lerner, Jennifer, Gross, James, Agesin, Bamikole Bamikole, Bernardo, Márcia, Campos, Olatz, Eudave, Luis, Grzech, Karolina, Ozery, Daphna Hausman, Jackson, Emily, Garcia, Elkin Oswaldo Luis, Drexler, Shira Meir, Jurković, Anita Penić, Rana, Kafeel, Wilson, John Paul, Antoniadi, Maria, Desai, Kermeka, Gialitaki, Zoi, Kushnir, Elizaveta, Nadif, Khaoula, Bravo, Olalla Niño, Nauman, Rafia, Oosterlinck, Marlies, Pantazi, Myrto, Pilecka, Natalia, Szabelska, Anna, van Steenkiste, I., Filip, Katarzyna, Bozdoc, Andreea Ioana, Marcu, Gabriela Mariana, Agadullina, Elena, Roczniewska, Marta, Reyna, Cecilia, Kassianos, Angelos, Westerlund, Minja, Ahlgren, Lina, Pöntinen, Sara, Adetula, Gabriel Agboola, Dursun, Pinar, Arinze, Azuka Ikechukwu, Arinze, Nwadiogo Chisom, Ogbonnaya, Chisom Esther, Dalgar, Ilker, Akkas, Handan, Macapagal, Paulo Manuel, Metin-Orta, Irem, Santos, Anabela Caetano, Mokady, Aviv, Reggev, Niv, Kurfali, Merve, Vasilev, Martin, Nock, Nora, Parzuchowski, Michal, Espinoza Barría, Mauricio, Vranka, Marek, Kohlová, Markéta Braun, Harutyunyan, Mikayel, Wang, Chunhui, Yao, Elvin, Becker, Maja, Manunta, Efisio, Marko, Dafne, Evans, Kortnee, Lewis, David, Findor, Andrej, Landry, Anais Thibault, Ortiz, Manuel, Grinberg, Maurice, Li, Ranran, Valentova, Jaroslava Varella, Mioni, Giovanna, Cellini, Nicola, Moon, Karis, Azab, Habiba, Levy, Neil, Karababa, Alper, Todsen, Anna Louise, van Schie, Kevin, Vintr, Jáchym, Kaliska, Lada, Križanić, Valerija, Samojlenko, Lara, Pourafshari, Razieh, Geiger, Sandra, Beitner, Julia, Warmelink, Lara, Ross, Robert, Hostler, Thomas, Szala, Anna, Grano, Caterina, Solorzano, Claudio Singh, Anjum, Gulnaz, Jimenez-Leal, William, Bradford, Maria, Pérez, Laura Calderón, Cruz Vásquez, Julio, Galindo-Caballero, Oscar, Vargas-Nieto, Juan Camilo, Kácha, Ondřej, Arvanitis, Alexios, Xiao, Qinyu, Cárcamo, Rodrigo, Zorjan, Saša, Tajchman, Zuzanna, Vilares, Iris, Pavlacic, Jeffrey, Kunst, Jonas, von Bastian, Claudia, Atari, Mohammad, Hricova, Monika, Schrötter, Jana, Rahal, Rima-Maria, Cohen, Noga, FatahModarres, Saiedeh, Zrimsek, Miha, Esteban-Serna, Celia, Calin-Jageman, Robert, Krafnick, Anthony, Štrukelj, Eva, Isager, Peder Mortvedt, Urban, Jan, Silva, Jaime, Martončik, Marcel, Očovaj, Sanja Batić, Šakan, Dušana, Kuzminska, Anna, Djordjevic, Jasna Milosevic, Almeida, Inês, Ferreira, Ana, Ricaurte, Danilo Zambrano, Monteiro, Renan, Etabari, Zahra, Dunleavy, Daniel, Chou, Weilun, Godbersen, Hendrik, Ruiz-Fernández, Susana, Reeck, Crystal, Kirgizova, Komila, Muminov, Abdumalik, Azevedo, Flavio, Alvarez, Daniela Serrato, Butt, Muhammad Mussaffa, Lee, Jeong Min, Chen, Zhang, Verbruggen, Frederick, Ziano, Ignazio, Tümer, Murat, Charyate, Abdelilah, Dubrov, Dmitrii, Tejada Rivera, María del Carmen M. C., Aberson, Christopher, Pálfi, Bence, Maldonado, Mónica Alarcón, Hubena, Barbora, Sacakli, Asli, Ceary, Chris, Richard, Karley, Singer, Gage, Perillo, Jennifer, Ballantyne, Tonia, Cyrus-Lai, Wilson, Fedotov, Maksim, Du, Hongfei, Wielgus, Magdalena, Pit, Ilse, Hruška, Matej, Sousa, Daniela, Szaszi, Barnabas, Adamus, Sylwia, Micheli, Leticia, Schmidt, Nadya-Daniela, Zsido, Andras, Paruzel-Czachura, Mariola, Bialek, Michal, Kowal, Marta, Sorokowska, Agnieszka, Misiak, Michal, Mola, Débora, Ortiz, María Victoria, Correa, Pablo Sebastián, Belaus, Anabel, Muchembled, Fany, Ribeiro, Rafael, Oliveira, Raquel, Szwed, Paulina, Kossowska, Małgorzata, Czarnek, Gabriela, Kielińska, Julita, Antazo, Benedict, Betlehem, Ruben, Nilsonne, Gustav, Simonovic, Nicolle, Taber, Jennifer, Gourdon-Kanhukamwe, Amélie, Domurat, Artur, Ihaya, Keiko, Yamada, Yuki, Urooj, Anum, Čadek, Martin, Bylinina, Lisa, Messerschmidt, Johanna, Kurfalı, Murathan, Adetula, Adeyemi, Baklanova, Ekaterina, Albayrak-Aydemir, Nihan, Kappes, Heather, Gjoneska, Biljana, House, Thea, Jones, Marc, Çoksan, Sami, Khaoudi, Ahmed, Bokkour, Ahmed, El Arabi, Kanza Ait, Djamai, Ikhlas, Iyer, Aishwarya, Parashar, Neha, Adiguzel, Arca, Kocalar, Halil Emre, Bundt, Carsten, Norton, James, Ankushev, Vladislav, Bogatyreva, Natalia, Grigoryev, Dmitry, Ivanov, Aleksandr, Prusova, Irina, Romanova, Marina, Sarieva, Irena, Terskova, Maria, Hristova, Evgeniya, Kadreva, Veselina Hristova, Janak, Allison, Askelund, Adrian Dahl, Pineda, Lina Maria Sanabria, Krupić, Dajana, Johannes, Niklas, Ouherrou, Nihal, Say, Nicolas, Sinkolova, Sladjana, Janjić, Kristina, Stojanovska, Marija, Stojanovska, Dragana, Khosla, Meetu, Thomas, Andrew, Kung, Franki, Bijlstra, Gijsbert, Mosannenzadeh, Farnaz, Balci, Busra Bahar, Reips, Ulf-Dietrich, Ishkhanyan, Byurakn, Czamanski-Cohen, Johanna, Dixson, Barnaby James Wyld, Moreau, David, Sutherland, Clare, Chuan-Peng, Hu, Noone, Chris, Topor, Marta, Kunisato, Yoshihiko, Yu, Karen, Daches, Shimrit, Vdovic, Milica, Anton-Boicuk, Lisa, Forbes, Paul, Kamburidis, Julia, Marinova, Evelina, Nedelcheva-Datsova, Mina, Rachev, Nikolay, Stoyanova, Alina, Koptjevskaja-Tamm, Maria, Bialobrzeska, Olga, Marszalek, Magdalena, Tatachari, Srinivasan, Afhami, Reza, Law, Wilbert, Žuro, Barbara, Van Doren, Natalia, Soto, Jose, Searston, Rachel, Miranda, Jacob, Damnjanović, Kaja, Yeung, Siu Kit, Krupić, Dino, Klevjer, Kristoffer, Lucas, Marc, Torres, Adriana Olaya, Toro, Mónica, Delgado, Lady Grey Javela, Vega, Diego, Solas, Sara Álvarez, Vilar, Roosevelt, Massoni, Sébastien, Frizzo, Thomas, Bran, Alexandre, Vaidis, David, Vieira, Luc, Paris, Bastien, Capizzi, Mariagrazia, Coelho, Gabriel Lins de Holanda, Greenburgh, Anna, Whitt, Cassie, Tullett, Alexa, Du, Xinkai, Volz, Leonhard, Bosma, Minke Jasmijn, Karaarslan, Cemre, Sarıoğuz, Eylül, Korbmacher, Max, Ribeiro, Matheus Fernando Felix, Verharen, Jeroen, Karekla, Maria, Karashiali, Christiana, Sunami, Naoyuki, Jaremka, Lisa, Habib, Sumaiya, Studzinska, Anna, Hanel, Paul, Holford, Dawn Liu, Wolfe, Kelly, Chiu, Faith, Theodoropoulou, Andriana, Ahn, El Rim, Lin, Yijun, Westgate, Erin, Brohmer, Hilmar, Hofer, Gabriela, Vezirian, Kevin, Feldman, Gilad, Travaglino, Giovanni, Ahmed, Afroja, Li, Manyu, Bosch, Jasmijn, Torunsky, Nathan, Bai, Hui, Manavalan, Mathi, Song, Xin, Walczak, Radoslaw, Zdybek, Przemysław, Friedemann, Maja, Alves, Sara, Correia, Rita, Rojas-Berscia, Luis Miguel, Uttley, Jim, Beshears, Julie, Thommesen, Katrine Krabbe, Behzadnia, Behzad, Geniole, Shawn, Silan, Miguel, Maturan, Princess Lovella G., Vilsmeier, Johannes, Tran, Ulrich, Izquierdo, Sara Morales, Mensink, Michael, Sorokowski, Piotr, Groyecka-Bernard, Agata, Radtke, Theda, Adoric, Vera Cubela, Carpentier, Joelle, Özdoğru, Asil Ali, Joy-Gaba, Jennifer, Hedgebeth, Mattie, Ishii, Tatsunori, Wichman, Aaron, Röer, Jan Philipp, Ostermann, Thomas, Davis, William, Suter, Lilian, Papachristopoulos, Konstantinos, Zabel, Chelsea, Mallik, Peter, Buchanan, Erin, Primbs, Maximilian, Moshontz, Hannah, Clinical Psychology, Medical Oncology, Laboratoire Inter-universitaire de Psychologie : Personnalité, Cognition, Changement Social (LIP-PC2S), Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Akdemir KurfalI, Merve, Cognition, Langues, Langage, Ergonomie (CLLE-LTC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Toulouse - Jean Jaurès (UT2J)-Centre National de la Recherche Scientifique (CNRS), Organizational Psychology, Medical and Clinical Psychology, Department of Social Psychology, Repositório da Universidade de Lisboa, Faculdade de Psicologia e de Ciências da Educação, and PDF ist zur Bearb. im Hiwi-Ordner, Sperre bis 28.02.2022, rechtl. Bedingungen: postprint, 6 Monate Embargo (Sherpa), 26.01.2022 bo

Subjects
Male, STRESS, Emotions, Psychological intervention, Social Sciences, [SHS.PSY]Humanities and Social Sciences/Psychology, REAPPRAISAL INTERVENTIONS, Behavioral neuroscience, NEGATIVE AND POSITIVE EMOTIONS, Behavioral Neuroscience, 0302 clinical medicine, ddc:150, [STAT.ML]Statistics [stat]/Machine Learning [stat.ML], Pandemic, Psychology, ANXIETY, Covid-19, reappraisal, emotions, R PACKAGE, purl.org/becyt/ford/5.1 [https], ComputingMilieux_MISCELLANEOUS, Repurposing, media_common, purl.org/becyt/ford/5 [https], 05 social sciences, DIVERGENT ASSOCIATIONS, POSITIVE EMOTIONS, 3. Good health, [SCCO.PSYC]Cognitive science/Psychology, MULTI-COUNTRY TEST, adult, COVID-19, female, humans, male, emotional regulation, emotions, Anxiety, Female, COGNITIVE REAPPRAISAL, Psychological resilience, medicine.symptom, [STAT.ME]Statistics [stat]/Methodology [stat.ME], Clinical psychology, Adult, Social Psychology, media_common.quotation_subject, Experimental and Cognitive Psychology, Article, 050105 experimental psychology, Cognitive reappraisal, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Human behaviour, medicine, Humans, 0501 psychology and cognitive sciences, METAANALYSIS, Behaviour Change and Well-being, pandemic, reappraisal, RESILIENCE, NEGATIVE AFFECT, Mental health, Emotional Regulation, REGULATION STRATEGIES, 030217 neurology & neurosurgery
Abstract

© The Author(s), under exclusive licence to Springer Nature Limited 2021, corrected publication 2022, The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world., This project was supported by funds from: the Amazon Web Services (AWS) Imagine Grant (to E.M.B.); the Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research (JSPS KAKENHI; 16h03079, 17h00875, 18k12015, and 20h04581 to Y.Y.); the research programme Dipartimenti di Eccellenza from the Ministry of Education University and Research (MIUR to N. Cellini and G.M. and the Department of General Psychology of the University of Padua); statutory funds of the University of Wroclaw (to A. Sorokowska); the Charles University Research Programme PROGRES (Q18 to M. Vranka); the Knut and Alice Wallenberg Foundation (2016:0229 to J.K.O.); the Rubicon Grant (019.183sg.007 to K.v.S.) from the Netherlands Organisation for Scientific Research; the Australian Research Council (dp180102384 to R.M.R.); the US National Institutes of Health (NIMH111640 to M.N.-D.), the Huo Family Foundation to N.J.; the NSF Directorate for Social, Behavioral and Economic Sciences, Division of Social and Economic Sciences (1559511 to J.S.L.); the US National Institutes of Health (RO1-CA-224545 to J.S.L.); Eesti Teadusagentuur–Estonian Research Council (PSG525 to A. Uusberg); the J. William Fulbright Program (to F. Azevedo); the HSE Basic Research Program (to D. Dubrov); Dominican University (a Faculty Development Grant to A. Krafnick); and the French National Research Agency Investissements d’avenir supporting PSF (ANR-15-IDEX-02 to H.I.); the Slovak Research and Development Agency (project no. APVV-20-0319 to M. Adamkovič); the programme FUTURE LEADER of Lorraine Université d’Excellence within the French National Research Agency Investissements d’avenir (ANR-15-IDEX-04-LUE to S.M.). Computation for this research was assisted by: the Harvard Business School compute cluster (HBSGrid); and the Open Science Grid. The Open Science Grid is supported by the National Science Foundation award 1148698 and the US Department of Energy’s Office of Science, as well as by the compute resources and assistance of the UW-Madison Center For High Throughput Computing (CHTC) in the Department of Computer Sciences. The CHTC is supported by UW-Madison, the Advanced Computing Initiative, the Wisconsin Alumni Research Foundation, the Wisconsin Institutes for Discovery, and the National Science Foundation, and is an active member of the Open Science Grid, which is supported by the National Science Foundation and the U.S. Department of Energy’s Office of Science.

Published
2021
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29. Invasive Candida kefyr infection presenting as pyelonephritis in an ICU hospitalized COVID-19 patient: Case report and review of the literature

Author

Spiliopoulou, A. Kolonitsiou, F. Vrioni, G. Tsoupra, S. Lekkou, A. Paliogianni, F. and Spiliopoulou, A. Kolonitsiou, F. Vrioni, G. Tsoupra, S. Lekkou, A. Paliogianni, F.

Abstract

Candida kefyr (Kluyveromyces marxianus), an ascomycetous environmental yeast, occasionally isolated from dairy products, represents an uncommon but emerging pathogen in immunocompromised patients. Herein, we present a case of C. kefyr pyelonephritis in a 41-year-old, previously immunocompetent, patient who was hospitalized in an COVID-19 ICU. Pyelonephritis was associated with caliectasis and obstruction due to possible fungus ball formation. Predisposing factors included ICU stay, use of broad spectrum antibiotics and steroids, central venous catheterization, mechanical ventilation and urologic manipulation. Susceptibility testing revealed high MIC values to amphotericin B. Infection was effectively controlled by prolonged administration of fluconazole without further surgical intervention. COVID-19 complicated with invasive candidiasis is an increasingly observed clinical situation that warrants high suspicion index and careful evaluation of laboratory data. © 2021 SFMM

Published
2022

31. Study on the Interaction between Serum Thyrotropin and Semen Parameters in Men

Author

Kakoulidis, Ioannis, primary, Ilias, Ioannis, additional, Stergiotis, Stefanos, additional, Togias, Stefanos, additional, Michou, Aikaterini, additional, Lekkou, Anastasia, additional, Mastrodimou, Vasiliki, additional, Pappa, Athina, additional, Milionis, Charalampos, additional, Venaki, Evangelia, additional, and Koukkou, Eftychia, additional

Published
2022
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32. Le contrat administratif européen

Author

Lekkou, Efthymia, Gervasoni, Véronique, Équipe de droit international, européen et comparé (EDIEC), Université Jean Moulin - Lyon 3 (UJML), and Université de Lyon-Université de Lyon

Subjects
[SHS.DROIT]Humanities and Social Sciences/Law, [SHS.DROIT] Humanities and Social Sciences/Law, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2022

34. La mutabilité des services publics, un principe en mutation ?

Author

Lekkou, Efthymia, Université Jean Moulin - Lyon 3 (UJML), Université de Lyon, Équipe de droit international, européen et comparé (EDIEC), Université de Lyon-Université de Lyon, and collaboration or project value

Subjects
Mutabilité du service public, [SHS.DROIT]Humanities and Social Sciences/Law, Principes du service public, Service Public, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

35. Insulin requirements during lactation in women with diabetes mellitus type 1 in comparison with pre-pregnancy levels: A 10-year retrospective study

Author

Ioannis Kakoulidis, Anastasia Lekkou, Ioannis Ilias, Aikaterini Michou, Charalampos Milionis, Evangelia Venaki, Eftychia Koukkou, and Anastasia Linardi

Subjects
musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Pediatrics, medicine.medical_specialty, endocrine system diseases, medicine.medical_treatment, Breastfeeding, Hypoglycemia, Pregnancy, Lactation, Diabetes mellitus, medicine, Humans, Insulin, Retrospective Studies, Pre pregnancy, business.industry, nutritional and metabolic diseases, Retrospective cohort study, medicine.disease, humanities, medicine.anatomical_structure, Breast Feeding, Diabetes Mellitus, Type 1, General Health Professions, Female, business, Metabolic profile
Abstract

The metabolic profile variability of women with diabetes mellitus type 1 (DM1) during breastfeeding, leads to a reassessment in managing glycemia, mainly to prevent hypoglycemia. In this retrospective study we assessed insulin needs, vis-à-vis breastfeeding in DM1. A 10.7% reduction of daily insulin dosage, compared to pre-pregnancy insulin needs, was noted in women who breastfed exclusively versus 10.8% in those who supplemented breastfeeding (p = NS). Women who experienced hypoglycemic episodes, tended (but not significantly) to be younger (

Published
2021

40. Commentaire de CJUE, 27 novembre 2012, Pringle, aff. C-370/12, comm. n° 97, conjoint avec commentaire de CJUE, 11 décembre 2018, Weiss, aff. C-493/17, comm. n° 140, p. 490-496 in Michaël Karpenschif et Cyril Nourissat (dir.)

Author

Lekkou, Efthymia, Équipe de droit international, européen et comparé (EDIEC), Université Jean Moulin - Lyon 3 (UJML), and Université de Lyon-Université de Lyon

Subjects
[SHS.DROIT]Humanities and Social Sciences/Law, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

43. Commentaire de CJCE, 6 octobre 1982, Srl CILFIT et Lanificio di Gavardo SpA c/ Ministère de la Santé, aff. 283/81, comm. n° 24, p. 127-132 in Michaël Karpenschif et Cyril Nourissat (dir.)

Author

Lekkou, Efthymia, Équipe de droit international, européen et comparé (EDIEC), Université Jean Moulin - Lyon 3 (UJML), and Université de Lyon-Université de Lyon

Subjects
[SHS.DROIT]Humanities and Social Sciences/Law, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

44. Tears evoke the intention to offer social support: A systematic investigation of the interpersonal effects of emotional crying across 41 countries

Author

Zickfeld, JH, Ven, NV, Pich, O, Schubert, TW, Berkessel, JB, Bhushan, B, Mateo, NJ, Barbosa, S, Sharman, L, Kokonyei, G, Schrover, E, Kardum, I, Aruta, JJB, Lazarevic, LB, Escobar, MJ, Stadel, M, Arriaga, P, Dodaj, A, Shankland, R, Majeed, NM, Li, YS, Lekkou, E, Hartanto, A, Ozdogru, AA, Vaughn, LA, Espinoza, MD, Caballero, A, Kolen, A, Karsten, J, Manley, H, Maeura, N, Eskisu, M, Shani, Y, Chittham, P, Ferreira, D, Bavolar, J, Konova, I, Sato, W, Morvinski, C, Carrera, P, Villar, S, Ibanez, A, Hareli, S, Garcia, AM, Kremer, I, Gotz, FM, Schwerdtfeger, A, Estrada-Mejia, C, Nakayama, M, Ng, WQ, Sesar, K, Orjiakor, CT, Dumont, K, Allred, TB, Gracanin, A, Rentfrow, PJ, Schonefeld, V, Vally, Z, Barzykowski, K, Peltola, HR, Tcherkassof, A, Haque, S, Smieja, M, Su-May, TT, IJzerman, H, Vatakis, A, Ong, CW, Choi, E, Schorch, SL, Paez, D, Malik, S, Kacmar, P, Bobowik, M, Jose, P, Vuoskoski, JK, Basabe, N, Dogan, U, Ebert, T, Uchida, Y, Zheng, MX, Mefoh, P, Sebena, R, Stanke, FA, Ballada, CJ, Blaut, A, Wu, Y, Daniels, JK, Kocsel, N, Burak, EGD, Balt, NF, Vanman, E, Stewart, SLK, Verschuere, B, Sikka, P, Boudesseul, J, Martins, D, Nussinson, R, Ito, K, Mentser, S, Colak, TS, Martinez-Zelaya, G, and Vingerhoets, A

Subjects
Emotional tears, Social support, Attachment, Cross-cultural, Emotional crying
Abstract

Tearful crying is a ubiquitous and likely uniquely human phenomenon. Scholars have argued that emotional tears serve an attachment function: Tears are thought to act as a social glue by evoking social support intentions. Initial experimental studies supported this proposition across several methodologies, but these were conducted almost exclusively on participants from North America and Europe, resulting in limited generalizability. This project examined the tears-social support intentions effect and possible mediating and moderating variables in a fully pre-registered study across 7007 participants (24,886 ratings) and 41 countries spanning all populated continents. Participants were presented with four pictures out of 100 possible targets with or without digitally added tears. We confirmed the main prediction that seeing a tearful individual elicits the intention to support, d = 0.49 [0.43, 0.55]. Our data suggest that this effect could be mediated by perceiving the crying target as warmer and more helpless, feeling more connected, as well as feeling more empathic concern for the crier, but not by an increase in personal distress of the observer. The effect was moderated by the situational valence, identifying the target as part of one's group, and trait empathic concern. A neutral situation, high trait empathic concern, and low identification increased the effect. We observed high heterogeneity across countries that was, via split-half validation, best explained by country-level GDP per capita and subjective well-being with stronger effects for higher-scoring countries. These findings suggest that tears can function as social glue, providing one possible explanation why emotional crying persists into adulthood.

Published
2021

45. Commentaire de CJUE, 16 décembre 2020, Conseil c/ K. Chrysostomides & Co. e.a., aff. jtes C-597, C-598, C-603 et 604/18 P, comm. n° 148, p. 724-727 in Michaël Karpenschif et Cyril Nourissat (dir.)

Author

Lekkou, Efthymia, Équipe de droit international, européen et comparé (EDIEC), Université Jean Moulin - Lyon 3 (UJML), and Université de Lyon-Université de Lyon

Subjects
[SHS.DROIT]Humanities and Social Sciences/Law, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

46. Evolution of epidemiological characteristics of infective endocarditis in Greece

Author

Giannitsioti, E. Pefanis, A. Gogos, C. Lekkou, A. Dalekos, G.N. Gatselis, N. Georgiadou, S. Nikou, P. Vrettou, A. Rigopoulos, A. Tryfonopoulos, C. Tsaganos, T. Karofilakis, E. Psarrakis, C. Argyriou, M. Gargalianos-Kakolyris, P. Adamis, G. Lourida, P. Kofteridis, D. Andrianaki, A. Loupa, C. Kostis, E. Sinapidis, D. Sympardi, S. Alexiou, N. Karaiskos, I. Masgala, A. Maltezos, E. Panagopoulos, P. Sachpekidis, V. Evdoridis, C. Sipsas, N.V. Daikos, G. Giamarellou, H. Pontikis, K. Lioris, I. Lelekis, M. Trikkas, A. Aggouras, D. Kolias, V. Rokkas, C. Nana-Anastasiou, M. Miyakis, S. On behalf of the Hellenic Society of Chemotherapy

Abstract

Objective: The clinical profile, management and outcome of infective endocarditis (IE) may be influenced by socioeconomic issues. Methods: A nationwide prospective study evaluated IE during the era of deep economic crisis in Greece. Epidemiological data and factors associated with 60-day mortality were analyzed through descriptive statistics, logistic and Cox-regression models. Results: Among 224 patients (male 72.3%, mean age 62.4 years), Staphylococcus aureus (n = 62; methicillin-resistant S. aureus (MRSA) 33.8%) predominated in the young without impact on mortality (p = 0.593), whilst Enterococci (n = 36) predominated in the elderly. Complications of IE were associated with mortality: heart failure [OR 2.415 (95% CI: 1.159–5.029), p = 0.019], stroke [OR 3.206 (95% CI: 1.190–8.632), p = 0.018] and acute kidney injury [OR 2.283 (95% CI: 1.085–4.805), p = 0.029]. A 60-day survival benefit was solely related to cardiac surgery for IE during hospitalization [HR 0.386 (95% CI: 0.165–0.903), p = 0.028] and compliance with antimicrobial treatment guidelines [HR 0.487 (95% CI: 0.259–0.916), p = 0.026]. Compared with a previous country cohort study, history of rheumatic fever and native valve predisposition had declined, whilst underlying renal disease and right-sided IE had increased (p < 0.0001); HIV infection had emerged (p = 0.002). No difference in rates of surgery and outcome was assessed. Conclusions: A country-wide survey of IE highlighted emergence of HIV, right-sided IE and predominance of MRSA in the youth during a severe socioeconomic crisis. Compliance with treatment guidelines promoted survival. © 2021 The Authors

Published
2021

49. TSH levels vis-à-vis total sperm count and testosterone levels

Author

Stefanos Stergiotis, Aikaterini Michou, Vaso Mastrodimou, Ioannis Ilias, Eftychia Koukkou, Ioannis Kakoulidis, Stefanos Togias, Anastasia Lekkou, Athina Pappa, and Evangelia Venaki

Subjects
medicine.medical_specialty, Endocrinology, Internal medicine, medicine, Testosterone (patch), Biology, Sperm
Published
2020
Full Text
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50. Thyroid function in pregnancy and atmospheric pollution

Author

Eftychia Koukkou, Stefanos Stergiotis, Aikaterini Michou, Ioannis Ilias, Vaso Mastrodimou, Anastasia Lekkou, Ioannis Kakoulidis, Stefanos Togias, Athina Pappa, and Evangelia Venaki

Subjects
Pregnancy, business.industry, Medicine, Physiology, Atmospheric pollution, Thyroid function, business, medicine.disease
Published
2020
Full Text
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