Search

Your search keyword '"Lejeune, J."' showing total 1,408 results
Start Over Author "Lejeune, J."
1,408 results on '"Lejeune, J."'

4. The Participatory Approach: A Specific French Organizational Model at the Department Level to Serve the Quality of Work Life of Healthcare Providers and the Quality of Care in Pediatric Oncology

Author

Lejeune J, Fouquereau E, Chênevert D, Coillot H, Chevalier S, Gillet N, Michon JM, Gandemer V, and Colombat P

Subjects
quality of work life, quality of care, organization, management, pediatric oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Julien Lejeune,1 Evelyne Fouquereau,2 Denis Chênevert,3 Helene Coillot,2 Severine Chevalier,2 Nicolas Gillet,2 Jean M Michon,4 Virginie Gandemer,5 Philippe Colombat2 1Service d’Onco-Hématologie Pédiatrique, Hôpital Clocheville, Tours, France; 2Qualipsy EE 1901, Université de Tours, Tours, France; 3Ecole des Hautes Etudes Commerciales, Montréal, Canada; 4Département de Pédiatrie, Institut Curie, Paris, France; 5Service d’Onco-Hématologie Pédiatrique, CHU Hôpital Sud, Rennes, FranceCorrespondence: Philippe Colombat Tel +33 0 2 47 4747 51Email philippe.colombat@univ-tours.frBackground: Care providers ‘psychological health at work is an important issue because it directly affects the quality of patient care. So far, few studies have studied the psychological health at work of care providers in paediatric oncology. The participatory approach (PA) is an innovative organizational model of department specific to France and previously associated with quality of work life (QWL) and job performance. The aim of the present study was to explore the relationships between the participatory approach, care providers’ QWL and quality of care of children in pediatric oncology departments in France.Methods: A multicentre survey was carried out in pediatric cancer units in France. Care providers completed a questionnaire assessing PA, QWL, consequences of QWL, and their perception of quality of care. The children or their parents completed a questionnaire assessing their perception of quality of care.Results: Five hundred and ten healthcare professionals working in French pediatric oncology centres (more than 40% of the healthcare staff in paediatric oncology in France), 142 children and 298 parents responded to the survey. PA was associated with the care providers’ QWL (β = 0.274; p < 0.001), work engagement (β = 0.167; p< 0.001), job satisfaction (β = 0.166; p< 0.001) and perception of quality of care (β = 0.236; p< 0.001). PA was also related to patients’ perception of quality of care notably regarding quality of communication (β = 0.161; p< 0.001) and information (β = 0.226; p< 0.001).Conclusion: PA is an innovative organizational model that appears to play a role in all aspects of healthcare providers’ QWL, and in the quality of care perceived by both care providers and patients.Keywords: quality of work life, quality of care, organization, management, pediatric oncology

Published
2021

8. A randomized controlled study assessing outcome, cognition, autonomy and quality of life in over 70-year-old patients after aneurysmal subarachnoid hemorrhage

Author

Proust, F., Bracard, S., Lejeune, J.-P., Thines, L., Leclerc, X., Penchet, G., Bergé, J., Morandi, X., Gauvrit, J.-Y., Mourier, K., Ricolfi, F., Lonjon, M., Sedat, J., Bataille, B., Droineau, J., Civit, T., Magro, E., Pelissou-Guyotat, I., Cebula, H., Lallouche, K., David, P., Emery, E., Courthéoux, P., Vignes, J.-R., Bénichou, J., Aghakani, N., Roche, P.-H., Gay, E., Bessou, P., Guabrillargues, J., and Irthum, B.

Published
2018
Full Text
View/download PDF

17. A Pragmatic Randomized Trial Comparing Surgical Clipping and Endovascular Treatment of Unruptured Intracranial Aneurysms

Author

Darsaut, T.E., primary, Findlay, J.M., additional, Bojanowski, M.W., additional, Chalaala, C., additional, Iancu, D., additional, Roy, D., additional, Weill, A., additional, Boisseau, W., additional, Diouf, A., additional, Magro, E., additional, Kotowski, M., additional, Keough, M.B., additional, Estrade, L., additional, Bricout, N., additional, Lejeune, J.-P., additional, Chow, M.M.C., additional, O’Kelly, C.J., additional, Rempel, J.L., additional, Ashforth, R.A., additional, Lesiuk, H., additional, Sinclair, J., additional, Erdenebold, U.-E., additional, Wong, J.H., additional, Scholtes, F., additional, Martin, D., additional, Otto, B., additional, Bilocq, A., additional, Truffer, E., additional, Butcher, K., additional, Fox, A.J., additional, Arthur, A.S., additional, Létourneau-Guillon, L., additional, Guilbert, F., additional, Chagnon, M., additional, Zehr, J., additional, Farzin, B., additional, Gevry, G., additional, and Raymond, J., additional

Published
2023
Full Text
View/download PDF

32. Spinal ependymomas in NF2: a surgical disease?

Author

Kalamarides, M., Essayed, W., Lejeune, J. P., Aboukais, R., Sterkers, O., Bernardeschi, D., Peyre, M., Lloyd, S. K., Freeman, S., Hammerbeck-Ward, C., Kellett, M., Rutherford, S. A., Evans, D. G., Pathmanaban, O., and King, A. T.

Published
2017
Full Text
View/download PDF

33. Clinical impact of NK-cell reconstitution after reduced intensity conditioned unrelated cord blood transplantation in patients with acute myeloid leukemia: analysis of a prospective phase II multicenter trial on behalf of the Société Française de Greffe de Moelle Osseuse et Thérapie Cellulaire and Eurocord

Author

Nguyen, S, Achour, A, Souchet, L, Vigouroux, S, Chevallier, P, Furst, S, Sirvent, A, Bay, J-O, Socié, G, Ceballos, P, Huynh, A, Cornillon, J, Francois, S, Legrand, F, Yakoub-Agha, I, Michel, G, Maillard, N, Margueritte, G, Maury, S, Uzunov, M, Bulabois, C-E, Michallet, M, Clement, L, Dauriac, C, Bilger, K, Lejeune, J, Béziat, V, Rocha, V, Rio, B, Chevret, S, and Vieillard, V

Published
2017
Full Text
View/download PDF

34. Gain in the short arm of chromosome 2 (2p+) induces gene overexpression and drug resistance in chronic lymphocytic leukemia: analysis of the central role of XPO1

Author

Cosson, A, Chapiro, E, Bougacha, N, Lambert, J, Herbi, L, Cung, H-A, Algrin, C, Keren, B, Damm, F, Gabillaud, C, Brunelle-Navas, M-N, Davi, F, Merle-Béral, H, Le Garff-Tavernier, M, Roos-Weil, D, Choquet, S, Uzunov, M, Morel, V, Leblond, V, Maloum, K, Lepretre, S, Feugier, P, Lesty, C, Lejeune, J, Sutton, L, Landesman, Y, Susin, S A, and Nguyen-Khac, F

Published
2017
Full Text
View/download PDF

43. Security and reliability of CUSTOMBONE cranioplasties: A prospective multicentric study

Author

Amelot, A., Nataloni, A., François, P., Cook, A.-R., Lejeune, J.-P., Baroncini, M., Hénaux, P.-L., Toussaint, P., Peltier, J., Buffenoir, K., Hamel, O., Hieu, P Dam, Chibbaro, S., Kehrli, P., Lahlou, M.A., Menei, P., Lonjon, M., Mottolese, C., Peruzzi, P., Mahla, K., Scarvada, D., Le Guerinel, C, Caillaud, P., Nuti, C., Pommier, B., Faillot, T., Iakovlev, G., Goutagny, Stéphane, Lonjon, N., Cornu, P., Bousquet, P., Sabatier, P., Debono, B., Lescure, J.-P., Vicaut, E., Froelich, S., Hieu, P. Dam, Le Guerinel, C., Sorbonne Université (SU), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Service de neurochirurgie [Rennes] = Neurosurgery [Rennes], CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Amiens-Picardie, Laboratoire d'ingénierie osteo-articulaire et dentaire (LIOAD), Université de Nantes (UN)-IFR26-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre hospitalier universitaire de Nantes (CHU Nantes), Institut Jean Le Rond d'Alembert (DALEMBERT), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Agroscope, Micro et Nanomédecines Translationnelles (MINT), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Département de Neurochirurgie [Hôpital Pasteur de Nice], Hôpital Pasteur [Nice] (CHU), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Service de neurochirurgie [CHU Clichy], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Beaujon [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité)

Subjects
Male, medicine.medical_treatment, MESH: Autografts, MESH: Plastic Surgery Procedures, Prosthesis, 0302 clinical medicine, Prospective Studies, CUSTOMBONE, Stage (cooking), Autografts, Explantation, MESH: Middle Aged, MESH: Follow-Up Studies, Prostheses and Implants, Middle Aged, Cranioplasty, MESH: Reproducibility of Results, 030220 oncology & carcinogenesis, Bone consolidation, MESH: Skull, Female, Infection, Craniotomy, Adult, medicine.medical_specialty, MESH: Prostheses and Implants, MESH: Craniotomy, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, MESH: Prosthesis Implantation, Prosthesis Implantation, 03 medical and health sciences, medicine, Humans, MESH: Humans, business.industry, Skull, Reproducibility of Results, MESH: Adult, Mean age, Plastic Surgery Procedures, Surgical procedures, Bone defect, MESH: Male, MESH: Prospective Studies, Surgery, Durapatite, Multicenter study, Neurology (clinical), Reconstruction, MESH: Durapatite, business, MESH: Female, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

Repairing bone defects generated by craniectomy is a major therapeutic challenge in terms of bone consolidation as well as functional and cognitive recovery. Furthermore, these surgical procedures are often grafted with complications such as infections, breaches, displacements and rejections leading to failure and thus explantation of the prosthesis.To evaluate cumulative explantation and infection rates following the implantation of a tailored cranioplasty CUSTOMBONE prosthesis made of porous hydroxyapatite. One hundred and ten consecutive patients requiring cranial reconstruction for a bone defect were prospectively included in a multicenter study constituted of 21 centres between December 2012 and July 2014. Follow-up lasted 2 years.Mean age of patients included in the study was 42±15 years old (y.o), composed mainly by men (57.27%). Explantations of the CUSTOMBONE prosthesis were performed in 13/110 (11.8%) patients, significantly due to infections: 9/13 (69.2%) (p0.0001), with 2 (15.4%) implant fracture, 1 (7.7%) skin defect and 1 (7.7%) following the mobilization of the implant. Cumulative explantation rates were successively 4.6% (SD 2.0), 7.4% (SD 2.5), 9.4% (SD 2.8) and 11.8% (SD 2.9%) at 2, 6, 12 and 24 months. Infections were identified in 16/110 (14.5%): 8/16 (50%) superficial and 8/16 (50%) deep. None of the following elements, whether demographic characteristics, indications, size, location of the implant, redo surgery, co-morbidities or medical history, were statistically identified as risk factors for prosthesis explantation or infection.Our study provides relevant clinical evidence on the performance and safety of CUSTOMBONE prosthesis in cranial procedures. Complications that are difficulty incompressible mainly occur during the first 6 months, but can appear at a later stage (1 year). Thus assiduous, regular and long-term surveillances are necessary.

Published
2021
Full Text
View/download PDF

44. Lenalidomide with or without erythropoietin in transfusion-dependent erythropoiesis-stimulating agent-refractory lower-risk MDS without 5q deletion

Author

Toma, A, Kosmider, O, Chevret, S, Delaunay, J, Stamatoullas, A, Rose, C, Beyne-Rauzy, O, Banos, A, Guerci-Bresler, A, Wickenhauser, S, Caillot, D, Laribi, K, De Renzis, B, Bordessoule, D, Gardin, C, Slama, B, Sanhes, L, Gruson, B, Cony-Makhoul, P, Chouffi, B, Salanoubat, C, Benramdane, R, Legros, L, Wattel, E, Tertian, G, Bouabdallah, K, Guilhot, F, Taksin, A L, Cheze, S, Maloum, K, Nimuboma, S, Soussain, C, Isnard, F, Gyan, E, Petit, R, Lejeune, J, Sardnal, V, Renneville, A, Preudhomme, C, Fontenay, M, Fenaux, P, and Dreyfus, F

Published
2016
Full Text
View/download PDF

45. Mare aging as young as 10 years old alters gene expression and structure of term placenta without affecting foal growth

Author

Derisoud, E, Gastaldo, S, Valais, O, Jouneau, Luc, Cauter, Van, Durand, A, Deliège, B, Rousset, A, Dahirel, M, Prezelin, A, Jaszczyszyn, Y, Wimel, L, Lejeune, J, Serteyn, D, Chavatte-Palmer, Pascale, Biologie de la Reproduction, Environnement, Epigénétique & Développement (BREED), École nationale vétérinaire - Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre Européen du Cheval [Belgique], Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Français du Cheval et de l'Equitation [Saumur] (IFCE), IFCE, and ICAR

Subjects
[SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health, gestation, age, pregnancy, horse, equine
Abstract

International audience; Maternal aging, excluding extreme ages, is associated with increased foal weight/size and heavier/more voluminous placenta. Maternal parity is a confounding factor as it is often strongly correlated with maternal age. The aim of this study was to analyze the effect of mare age, while excluding a parity effect, on placental structure and gene expression and foal growth and health.Placentas from 10 young (6-year-old, YM) and 12 older (>10-year-old, OM) multiparous mares of similar parity were recovered, measured and weighted after foaling. Placental structure was analyzed by stereology on HES stained histological slides. Paired-end RNA-sequencing was performed on 6 placentas/group (Illumina, NextSeq500). Differential expression was analyzed (DESeq2) using a false discovery rate

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results