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1,197 results on '"Leitzmann, Michael F."'

2. Large-scale assessment of physical activity in a population using high-resolution hip-worn accelerometry: the German National Cohort (NAKO)

Author

Weber, Andrea, van Hees, Vincent T., Stein, Michael J., Gastell, Sylvia, Steindorf, Karen, Herbolsheimer, Florian, Ostrzinski, Stefan, Pischon, Tobias, Brandes, Mirko, Krist, Lilian, Marschollek, Michael, Greiser, Karin Halina, Nimptsch, Katharina, Brandes, Berit, Jochem, Carmen, Sedlmeier, Anja M., Berger, Klaus, Brenner, Hermann, Buck, Christoph, Castell, Stefanie, Dörr, Marcus, Emmel, Carina, Fischer, Beate, Flexeder, Claudia, Harth, Volker, Hebestreit, Antje, Heise, Jana-Kristin, Holleczek, Bernd, Keil, Thomas, Koch-Gallenkamp, Lena, Lieb, Wolfgang, Meinke-Franze, Claudia, Michels, Karin B., Mikolajczyk, Rafael, Kluttig, Alexander, Obi, Nadia, Peters, Annette, Schmidt, Börge, Schipf, Sabine, Schulze, Matthias B., Teismann, Henning, Waniek, Sabina, Willich, Stefan N., Leitzmann, Michael F., and Baurecht, Hansjörg

Published
2024
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3. Costs associated with insufficient physical activity in Germany: cross-sectional results from the baseline examination of the German national cohort (NAKO)

Author

Gottschalk, Sophie, König, Hans-Helmut, Weber, Andrea, Leitzmann, Michael F., Stein, Michael J., Peters, Annette, Flexeder, Claudia, Krist, Lilian, Willich, Stefan N., Nimptsch, Katharina, Pischon, Tobias, Gastell, Sylvia, Steindorf, Karen, Herbolsheimer, Florian, Ebert, Nina, Michels, Karin B., Dorrn, Anja, Harth, Volker, Obi, Nadia, Karch, André, Teismann, Henning, Völzke, Henry, Meinke-Franze, Claudia, Klimeck, Leon, Seum, Teresa L., and Dams, Judith

Published
2024
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6. Sedentary Behaviour and Adiposity

Author

Jochem, Carmen, Schmid, Daniela, Leitzmann, Michael F., Ahrens, Wolfgang, Series Editor, Pigeot, Iris, Series Editor, Leitzmann, Michael F., editor, Jochem, Carmen, editor, and Schmid, Daniela, editor

Published
2023
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10. Longitudinal associations of sedentary behavior and physical activity with body composition in colorectal cancer survivors up to 2 years post treatment

Author

Kenkhuis, Marlou-Floor, Klingestijn, Mo, Fanshawe, Anne-Marie, Breukink, Stéphanie O., Janssen-Heijnen, Maryska L. G., Keulen, Eric T. P., Rinaldi, Sabina, Vineis, Paolo, Gunter, Marc J., Leitzmann, Michael F., Scalbert, Augustin, Weijenberg, Matty P., Bours, Martijn J. L., and van Roekel, Eline H.

Published
2023
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11. Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study

Author

Sedlmeier, Anja M., Viallon, Vivian, Ferrari, Pietro, Peruchet-Noray, Laia, Fontvieille, Emma, Amadou, Amina, Seyed Khoei, Nazlisadat, Weber, Andrea, Baurecht, Hansjörg, Heath, Alicia K., Tsilidis, Kostas, Kaaks, Rudolf, Katzke, Verena, Inan-Eroglu, Elif, Schulze, Matthias B., Overvad, Kim, Bonet, Catalina, Ubago-Guisado, Esther, Chirlaque, María-Dolores, Ardanaz, Eva, Perez-Cornago, Aurora, Pala, Valeria, Tumino, Rosario, Sacerdote, Carlotta, Pasanisi, Fabrizio, Borch, Kristin B., Rylander, Charlotta, Weiderpass, Elisabete, Gunter, Marc J., Fervers, Béatrice, Leitzmann, Michael F., and Freisling, Heinz

Published
2023
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25. Sedentary Behaviour and Adiposity

Author

Jochem, Carmen, Schmid, Daniela, Leitzmann, Michael F., Ahrens, Wolfgang, Series editor, Pigeot, Iris, Series editor, Leitzmann, Michael F., editor, Jochem, Carmen, editor, and Schmid, Daniela, editor

Published
2018
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29. Targeted agents in patients with progressive glioblastoma—A systematic meta‐analysis of randomized clinical trials.

Author

Ippen, Franziska Maria, Scherm, Angelika, Kessler, Tobias, Hau, Peter, Agkatsev, Sarina, Baurecht, Hansjörg, Wick, Wolfgang, Knüttel, Helge, Leitzmann, Michael F., and Seliger‐Behme, Corinna

Subjects
CLINICAL trials, BRAIN tumors, GLIOBLASTOMA multiforme, OVERALL survival, PROGRESSION-free survival, PROGNOSIS
Abstract

Background: Glioblastoma (GB) is the most common malignant primary brain tumor in adults and is associated with a poor prognosis. Current treatment guidelines outline the standard of care for patients with newly diagnosed GB; however, there is currently no well‐established consensus for the treatment of progressive GB. With this systematic meta‐analysis of recently published randomized controlled trials (RCTs), we aim to establish evidence on targeted agents in the treatment of patients with progressive GB. Material and Methods: We conducted searches across the Cochrane Library, Pubmed, MEDLINE (Ovid), ClinicalTrials.gov, WHO's International Clinical Trials Registry Platform and Google Scholar, encompassing the time span from 1954 to 2022, aiming to identify RCTs evaluating targeted therapies in patients with progressive GB. In order to perform a random‐effects meta‐analysis, we extracted hazard ratios (HRs) of overall survival (OS) and progression‐free survival (PFS). Results: We included 16 RCTs (n = 3025 patients) in the systematic meta‐analysis. Formally, regorafenib (RR 0.50; 95% CI 0.33–0.75), Depatux‐M + TMZ (RR 0.66; 95% CI 0.47–0.93) and rindopepimut + bevacizumab (RR 0.53; 95% CI 0.32–0.88) were associated with an improved OS compared to the control arm. The combination of bevacizumab + CCNU (RR = 0.49; 95% CI 0.35–0.69) and regorafenib (RR 0.65; 95% CI 0.44–0.95) were formally associated with improved PFS. Conclusions: The aim of this systematic meta‐analysis was to establish evidence for the use of targeted therapies in progressive GB. While some studies demonstrated benefits for OS and/or PFS, those results have to be interpreted with caution as most studies had major methodological weaknesses, including potential differences in sample size, trial design, or the initial distribution of prognostic factors. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Anthropometrische Messungen in der NAKO Gesundheitsstudie – mehr als nur Größe und Gewicht

Author

Fischer, Beate, Sedlmeier, Anja M., Hartwig, Saskia, Schlett, Christopher L., Ahrens, Wolfgang, Bamberg, Fabian, Baurecht, Hansjörg, Becher, Heiko, Berger, Klaus, Binder, Hans, Bohn, Barbara, Carr, Prudence R., Castell, Stefanie, Franzke, Claus-Werner, Fricke, Julia, Gastell, Sylvia, Greiser, Karin Halina, Günther, Kathrin, Jaeschke, Lina, Kaaks, Rudolf, Kemmling, Yvonne, Krist, Lilian, Kuß, Oliver, Legath, Nicole, Lieb, Wolfgang, Linseisen, Jakob, Löffler, Markus, Michels, Karin B., Mikolajczyk, Rafael, Niedermaier, Tobias, Norman, Kristina, Obi, Nadia, Peters, Annette, Pischon, Tobias, Schikowski, Tamara, Schipf, Sabine, Schmidt, Börge, Schulze, Matthias B., Stang, Andreas, Stojicic, Jelena, Tiller, Daniel, Völzke, Henry, Waniek, Sabina, and Leitzmann, Michael F.

Published
2020
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32. Association between physical activity and risk of hepatobiliary cancers: A multinational cohort study

Author

Baumeister, Sebastian E., Schlesinger, Sabrina, Aleksandrova, Krasimira, Jochem, Carmen, Jenab, Mazda, Gunter, Marc J., Overvad, Kim, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Carbonnel, Franck, Fournier, Agnès, Kühn, Tilman, Kaaks, Rudolf, Pischon, Tobias, Boeing, Heiner, Trichopoulou, Antonia, Bamia, Christina, La Vecchia, Carlo, Masala, Giovanna, Panico, Salvatore, Fasanelli, Francesca, Tumino, Rosario, Grioni, Sara, Bueno de Mesquita, Bas, Vermeulen, Roel, May, Anne M., Borch, Kristin B., Oyeyemi, Sunday O., Ardanaz, Eva, Rodríguez-Barranco, Miguel, Dolores Chirlaque López, María, Felez-Nobrega, Mireia, Sonestedt, Emily, Ohlsson, Bodil, Hemmingsson, Oskar, Werner, Mårten, Perez-Cornago, Aurora, Ferrari, Pietro, Stepien, Magdalena, Freisling, Heinz, Tsilidis, Konstantinos K., Ward, Heather, Riboli, Elio, Weiderpass, Elisabete, and Leitzmann, Michael F.

Published
2019
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33. Sustainable diets and risk of overweight and obesity: A systematic review and meta‐analysis.

Author

Reger, Christoph, Leitzmann, Michael F., Rohrmann, Sabine, Kühn, Tilman, Sedlmeier, Anja M., and Jochem, Carmen

Subjects
*OBESITY, *DIET, *CLIMATE change, *PUBLICATION bias
Abstract

Summary: Sustainable diets are gaining interest as a possible approach to tackle climate change and the global extent of obesity. Yet, the association between sustainable diets and adiposity remains unclear. We performed a systematic review and meta‐analysis, calculating summary relative risks and 95% confidence intervals (CI). We pooled maximally adjusted risk estimates, assessed heterogeneity and publication bias, calculated the E‐value, and evaluated the risk of bias across the included studies. A total of eight studies were eligible for analysis. Comparing the highest versus the lowest levels of adherence to sustainable diets, the pooled effect estimate was 0.69 (95% CI = 0.62–0.76) for overweight and 0.61 (95% CI = 0.47–0.78) for obesity. These results suggest that sustainable diets may decrease the risk of overweight/obesity and therefore could serve as enablers for improving both public and planetary health. An agreed‐upon clear definition of sustainable diets would enhance the comparability of future studies in this area. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Herpes zoster incidence in Germany - an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort

Author

Caputo, Mahrrouz, Horn, Johannes, Karch, André, Akmatov, Manas K., Becher, Heiko, Braun, Bettina, Brenner, Hermann, Castell, Stefanie, Fischer, Beate, Giani, Guido, Günther, Kathrin, Hoffmann, Barbara, Jöckel, Karl-Heinz, Keil, Thomas, Klüppelholz, Birgit, Krist, Lilian, Leitzmann, Michael F., Lieb, Wolfgang, Linseisen, Jakob, Meisinger, Christa, Moebus, Susanne, Obi, Nadia, Pischon, Tobias, Schipf, Sabine, Schmidt, Börge, Sievers, Claudia, Steinbrecher, Astrid, Völzke, Henry, and Mikolajczyk, Rafael

Published
2019
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43. Calcium intake in vegan and vegetarian diets: A systematic review and Meta-analysis.

Author

Bickelmann, Franziska V., Leitzmann, Michael F., Keller, Markus, Baurecht, Hansjörg, and Jochem, Carmen

Subjects
*VEGANISM, *CALCIUM, *PLANT-based diet, *DIETARY calcium, *FOOD consumption
Abstract

In recent years, plant-based diets have experienced increasing popularity. However, plant-based diets may not always ensure an adequate supply of micronutrients, in particular calcium. We performed a systematic review and meta-analysis of calcium intake in vegan and vegetarian diets as compared to omnivorous diets. We searched PubMed and Web of Science and identified 2,009 potentially relevant articles. Mean calcium intake values were pooled and standardized mean differences (SMD) and 95% confidence intervals (CI) were computed. We analyzed 74 studies, including 7,356 vegan, 51,940 vegetarian, and 107,581 omnivorous participants. Of these, dietary calcium intake was examined in 23 studies of vegans, 60 studies of vegetarians and 74 studies of omnivores. Vegans showed a substantially lower calcium intake than vegetarians (SMD = −0.57; 95%CI = −0.83 to −0.32; p = <0.0001) and omnivores (SMD = −0.70; 95%CI = −0.95 to −0.59; p < 0.0001), whereas no statistically significant difference in calcium intake was noted between vegetarians and omnivores (SMD = 0.07; 95%CI = −0.04 to 0.19; p = 0.1976). In conclusion, vegans show a lower calcium intake than vegetarians and omnivores. This finding emphasizes the need for vegans to monitor their calcium status. [ABSTRACT FROM AUTHOR]

Published
2023
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