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Background: Little is known about family mental illness and substance use disorder (SUD). This casecontrol study explored the relationship between family (parents and/or siblings) mental health problems (FMHP) and lifetime substance use disorder (SUD), considering a gender perspective. Methods: A sample of 387 patients (n = 306 men, 79.1%; n = 81 women, 20.9%) was recruited from the Proyecto Hombre Navarra (Spain) addiction treatment program. Patients with (80 men; 24 women) and without (226 men; 57 women) FMHP were compared, taking sex into account. Results: The prevalence of FMHP was 26.9%, without significant differences between men (n = 80; 26.1%) and women (n = 24; 29.6%). Men with FMHP reported higher severity in family/social and psychiatric areas than those without FMHP. Women with FMHP reported a higher severity in the psychiatric area and a higher prevalence of anxiety problems, suicidal attempts, previous psychopharmacological treatments, and physical abuse than women without FMHP. Conclusions: FMHP is highly prevalent in patients with SUD. They are associated with lifetime psychopathological problems, mainly in men. Further specific research is needed to evaluate this issue to develop specific treatments tailored to the needs of patients with FMHP. This project was supported by a grant [code PSI2016–76511-R] from the Agencia Estatal de Investigación (AEI) of the Spanish Government and Fondo Europeo de Desarrollo Regional of the European Union (FEDER, EU) and by a grant [589/2021] from Universidad Publica de Navarra and Fundación Bancaria Caja Navarra. Open access funding provided by Universidad Pública de Navarra.

Suicidal-related behaviours are an important concern in individuals who present with substance use disorders (SUDs). The distinction among the specific characteristics of the different patients might help to improve prevention strategies. We describe and compare the sociodemographic characteristics, severity of addiction, and psychopathology of the participants depending on the severity of their lifetime suicidal behaviour. In addition, we examine whether the number of suicide attempts can be estimated based on the variables that differentiate the groups. A sample of 318 men and 86 women who sought treatment for addiction were assessed. The sample was divided into: no ideation or attempts, suicidal ideation, one suicide attempt, and two or more suicide attempts. The group with two or more suicide attempts exhibited a greater severity in the addiction profile. The group with one suicide attempt presented a higher psychopathological symptomatology at the time of the assessment. The severity of the Psychiatric area was related to the group with two or more attempts and to the number of suicide attempts. The presence of any number of attempts is associated with greater severity of addiction. Providing specific intervention strategies for SUD patients depending on their suicidal behaviours is promising for clinical application. The first author was supported by a grant from the European UnionNext Generation EU by Ministerio de Universidades (Gobierno de España) and Universidad del País Vasco (UPV/EHU). The second author was supported by a grant (589/2021) from Universidad Pública de Navarra and Fundación Bancaria Caja Navarra. Open access funding provided by Universidad Pública de Navarra

Background The long-term negative effects of adverse childhood experiences (ACEs) and their impact on physical and mental health has been widely studied. However, research about the relationship between ACEs and substance use disorder (SUD) diagnosis in adolescence and adulthood is still scarce. Therefore, this scoping review was conducted to collect the existing research findings to explore the relationship between the experience of ACEs and the diagnosis of SUD later in life. Methods The PsycINFO, Medline, Scopus, Web of Science, and Cochrane Library databases were searched. After identifying the records based on eligibility and exclusion criteria, 12 studies were finally selected for inclusion. Results Most of the studies were conducted in the USA with adult male and female participants. All studies were cross-sectional in nature and assessed ACEs retrospectively. The main conclusions of the studies were that there is a higher prevalence of ACEs in the population with SUD than in the general population, and a positive association between ACEs and the development and severity of SUD in adolescence and adulthood. Conclusions It is difficult to make comparisons between studies and to draw solid conclusions because of the lack of standardized criteria for evaluating ACEs and due to the heterogeneity in the substance types examined. More research is needed to fully elucidate the underlying mechanism of the relationship between ACEs and SUD.

Objective This study explored the differential psychopathological profile between male perpetrators of intimate partner violence (IPV) with and without problematic alcohol use (PAU). Method A sample of 981 men was recruited from a specialized IPV perpetrators treatment programme. All of them were assessed with the Symptom Checklist-90-Revised (SCL-90-R), the State-Trait Anger Expression Inventory-2 (STAXI-2), and the Millon Clinical Multiaxial Inventory-III (MCMI-III). Comparisons between perpetrators with (n = 125) and without (n = 856) PAU on all the variables studied were carried out. Results Perpetrators with PAU were less frequently employed and had higher rates of previous psychiatric history and childhood family violence. Moreover, they presented with higher levels of cognitive biases about women and violence. On a psychopathological level, participants with PAU reported significantly higher scores on the SCL-90-R, on the STAXI-2, and on almost all the MCMI-III scales than did those without PAU. The multivariate logistic regression analyses showed that the main variables related to PAU were as follows: higher levels of previous psychiatric history, distorted thoughts about women, depression, drug dependence, and various personality disorders (bipolar, dysthymia, antisocial, avoidant, borderline, and schizotypal); and lower scores on internal control, anger reaction, paranoid ideation, and schizoid personality disorders. Discussion IPV perpetrators with PAU have a more severe psychopathological profile than those without PAU. Additionally, several variables along with PAU may have contributed to the development of IPV. Therefore, tailored interventions should be developed for those perpetrators with PAU.