39 results on '"Leila Khalil"'
Search Results
2. Analyzing the Effective Factors of and Barriers to Benefactors’ Participation in the Construction and Equipment of Public Libraries: A Qualitative Study
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Mahsa Naghizadeh Dehkharghani, Leila Khalili, and Behbood Yarigholi
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public libraries ,library benefactors ,east azerbaijan (iran) ,qualitative research ,Bibliography. Library science. Information resources ,Information technology ,T58.5-58.64 - Abstract
Objective: The purpose of this research was to analyze the factors and barriers affecting banefactpors’ participation of benefactors in the construction and equipment of public libraries in East Azerbaijan province. Method: The present applied research was carried out with a qualitative approach and conventional qualitative content analysis method. The participants of the study included all the benefactors partaking in the construction and equipment of public libraries in East Azerbaijan province who had two conditions; participation within the years 1389 to 1400 and participation valued more than one hundred million Rials. The samples were purposefully selected for a semi-structured interview. The interview was conducted up to the theoretical saturation stage and a total of eleven benefactors were interviewed. In order to validate the findings, criteria such as credibility, transferability, dependability and confirmability were used. The findings were analyzed using conventional qualitative content analysis methods. Findings: Based on analyzing interview transcripts, 88 semantic codes, 20 sub-categories (regulations and statutes, activation of the Association of Library Benefactors, advertising, training and veneration, organizational support for employees, the ability to communicate with government officials, the skills of attracting benefactors, the skills of retaining benefactors, the function of country laws, the function of governance, benefactors' cultural contexts, benefactors' economic and social contexts, cultural beliefs, personality beliefs, religious and moral beliefs, bureaucratic obstacles, financial obstacles, lack of proper management, inefficient culture-making, governance shortcomings, and the shortcomings of the country's laws), seven general categories (the role of public libraries foundation in the motivation of benefactors, the role of library officials in the motivation of benefactors, the effect of governance and laws in the motivation of benefactors, impact of cultural, economic and social contexts on the motivation of benefactors, personal beliefs of benefactors, shortcomings of the public libraries foundation in the motivation of benefactors and shortcomings of governance and laws in the motivation of benefactors) and two main components (motivational factors in attracting benefactors and barriers to attracting benefactors) were identified. Based on the emphasis of the participating benefactors, it can be concluded that among the effective factors in benefactors’ participation in the construction and equipment of public libraries, the cultural, economic and social context as well as personal beliefs were the most two important motivational factors. Also, according to participating benefactors, the most important obstacle to non-participation of benefactors in the construction and equipment of the library was the lack of sufficient enlightenment for the necessity of the library, which indicates a weakness in culture building. Originality/value: In order to expand library benefactors’ participation, it is necessary that the Institution of Public Libraries (as the guardian of the expansion of public libraries) should pay special attention to the effective motivational factors in this participation and the obstacles in this path. The present study adopted a qualitative approach to identify the factors affecting the benefactors’ participation in the construction and equipment of public libraries from the viewpoint of participating benefactors. The findings of this research can provide the managers and experts of the Institution of Public Libraries with more accurate information and perspective for more precise planning and removing obstacles and shortcomings in this field. It can also provide a basis for conducting future research in this field and expanding its theoretical foundations.
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- 2024
3. Examining the Lived Experiences of Researchers in Using Scientific Social Networks: A Phenomenological Study
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Leila Khalili, Leila pourmohammad, and Behboud Yarigholi
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researchers ,phenomenology ,lived experiences ,azarbaijan shahid madani university ,scientific social networks ,academia ,linkedin ,mendaly ,researchgate ,Information technology ,T58.5-58.64 ,Information theory ,Q350-390 - Abstract
Purpose: The purpose of this research is to analyze the lived experiences of researchers of Azarbaijan Shahid Madani University in using scientific social networks.Methodology: The current research was conducted with a qualitative approach and interpretive phenomenology method. The population of this research were academic staff members of the university, and 20 samples were selected by the criteria-based purposeful sampling method to obtain their experiences. The interviews were conducted in a semi-structured manner and continued until the theoretical saturation stage. Findings: Based on the findings of the research, 349 codes were extracted from the lived experiences of researchers which were placed in 180 semantic units and 29 categories. Finally, four themes were extracted from 29 categories. The themes were how researchers get to know scientific social networks, contexts and reasons for using these networks, the capabilities of scientific networks, and barriers and challenges of these networks. Conclusion: The capabilities and facilities provided in scientific social networks are the reason for using such networks. Researchers' further familiarity with the capabilities of these networks and strengthening and fixing their shortcomings will lead to broader usage of this online space of scientific community.
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- 2023
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4. 616 Comparison of optical and ultrasound imaging in lupus arthritis
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Xin Wang, Anca Askanase, Laura Geraldino-Pardilla, Wei Tang, Leila Khalili, Alessandro Marone, Andreas Hielscher, Sean Inzerillo, Shane Murray, Moegammad Bardien, Vedant Gaikwad, and Stephen Kim
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2024
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5. 104 Demographic and clinical factors that contribute to clinical study enrollment in systemic lupus erythematosus
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Anca Askanase, Peter Izmirly, Wei Tang, Yevgeniya Gartshteyn, Leila Khalili, Noa Schwartz, Sean Inzerillo, Nancyanne Schmidt, Wai Yan April Fu, and Laura Geraldino- Pardilla
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2024
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6. SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis
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Yevgeniya Gartshteyn, Laura Geraldino-Pardilla, Leila Khalili, Shoiab Bukhari, Shalom Lerrer, Robert J. Winchester, Anca D. Askanase, and Adam Mor
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systemic lupus ,lupus nephritis ,T peripheral helper cells ,T follicular helper cells ,SLAM ,SAP ,Immunologic diseases. Allergy ,RC581-607 - Abstract
IntroductionT follicular (TFH) and peripheral helper (TPH) cells have been increasingly recognized as a pathogenic subset of CD4 T cells in systemic lupus erythematosus (SLE). The SLAM Associated Protein (SAP) regulates TFH and TPH function by binding to the co-stimulatory signaling lymphocyte activation molecule family (SLAMF) receptors that mediate T cell - B cell interactions. SAP and SLAMF are critical for TPH-dependent B cell maturation into autoantibody-producing plasma cells that characterize SLE pathogenesis. We hypothesized that SAP-expressing TPH cells are involved in the pathogenesis of lupus nephritis (LN).MethodsPeripheral blood mononuclear cells (PBMC) were isolated using density gradient separation from whole blood. Cells were stained for cell surface markers, followed by permeabilization and staining of intracellular SAP for spectral flow cytometry analysis. We also analyzed SAP expression from renal infiltrating LN T cells using the available single-cell RNA sequencing (scRNA seq) Accelerated Medicines Partnership (AMP) SLE dataset.ResultsPBMC from 30 patients with SLE (34 ± 10 years old, 83% female), including 10 patients with LN, were analyzed. We found an increase in total SAP-positive CD4 and CD8 T cells in SLE compared with controls (55.5 ± 2.6 vs. 41.3 ± 3.4, p=0.007, and 52.5 ± 3.0 vs. 39.2 ± 2.8, p=0.007 respectively). In CD4 T cells, the highest SAP expression was in the TPH subset. The frequency of SAP+TPH in circulation correlated with disease activity; SLE patients with renal disease had higher levels of circulating SAP+TPH that remained significant after adjusting for age, sex, race, low complements, and elevated anti-dsDNA (p=0.014). scRNA-seq data of renal infiltrating T cells in LN identified SAP expression to localize to the TFH-like CD4 cluster and GZMK+ CD8 cluster. Increased SAP expression in LN was associated with the differential expression of SLAMF3 and SLAMF7 and granzyme K and EOMES. The existence of two predominant SAP-expressing subsets, the TFH-like CD4 T cells, and GZMK+ effector CD8 T cells, was verified using scRNA-seq data from a human transcriptomic atlas of fifteen major organs.ConclusionThe expansion of SAP-expressing T helper cells was associated with LN in our cohort and verified using scRNA-seq data of renal infiltrating T cells. Improved SLAM and SAP signaling understanding can identify new therapeutic targets in LN.
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- 2024
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7. The Role of Akkermansia muciniphila on Improving Gut and Metabolic Health Modulation: A Meta-Analysis of Preclinical Mouse Model Studies
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Leila Khalili, Gwoncheol Park, Ravinder Nagpal, and Gloria Salazar
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Akkermansia muciniphila ,Desulfovibrio ,Family XIII AD3011 group ,Candidatus Saccharimonas ,gut ,metabolic health ,Biology (General) ,QH301-705.5 - Abstract
Akkermansia muciniphila (A. muciniphila) and its derivatives, including extracellular vesicles (EVs) and outer membrane proteins, are recognized for enhancing intestinal balance and metabolic health. However, the mechanisms of Akkermansia muciniphila’s action and its effects on the microbiome are not well understood. In this study, we examined the influence of A. muciniphila and its derivatives on gastrointestinal (GI) and metabolic disorders through a meta-analysis of studies conducted on mouse models. A total of 39 eligible studies were identified through targeted searches on PubMed, Web of Science, Science Direct, and Embase until May 2024. A. muciniphila (alive or heat-killed) and its derivatives positively affected systemic and gut inflammation, liver enzyme level, glycemic response, and lipid profiles. The intervention increased the expression of tight-junction proteins in the gut, improving gut permeability in mouse models of GI and metabolic disorders. Regarding body weight, A. muciniphila and its derivatives prevented weight loss in animals with GI disorders while reducing body weight in mice with metabolic disorders. Sub-group analysis indicated that live bacteria had a more substantial effect on most analyzed biomarkers. Gut microbiome analysis using live A. muciniphila identified a co-occurrence cluster, including Desulfovibrio, Family XIII AD3011 group, and Candidatus Saccharimonas. Thus, enhancing the intestinal abundance of A. muciniphila and its gut microbial clusters may provide more robust health benefits for cardiometabolic, and age-related diseases compared with A. muciniphila alone. The mechanistic insight elucidated here will pave the way for further exploration and potential translational applications in human health.
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- 2024
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8. The role of student government in colleges with particular reference to Beirut College for Women. (c1965)
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Leila Khalil Khoury
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- 2017
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9. The Predictive Role of Information Literacy in Promoting Librarians' Creativity and Job Involvement
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Leila Khalili, Isa Azarang, and Abulfzal Ghasemzadeh Alishahi
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west azerbaijan (iran) ,public libraries ,information literacy ,creativity ,job involvement ,Bibliography. Library science. Information resources - Abstract
Purpose: The main purpose of this study is to investigate the effect of information literacy on creativity and job involvement of librarians. Methodlogy: This applied and quantitative research was conducted with survey method. The data collection tools were three standard questionnaires. The face validity of the measurement tool was confirmed by experts and its reliability was calculated using Cronbach's alpha coefficient, which was 0.94 for information literacy, 0.71 for creativity and 0.85 for job involvement. The statistical population was a total number of 148 librarians affiliated to the Public Libraries of West Azerbaijan Province that 121 of them completed the questionnaire. Statistical analyzes were performed using SPSS software.Findlings: Based on Pearson test, there was a positive and significant relationship between librarians' information literacy with their creativity (r = 0.351) and job involvement (r = 0.276). Also, a positive and significant relationship (r = 0.240) was observed between creativity and job involvement of librarians. Findings of multiple regression test showed that creativity can be predicted by two dimensions of information literacy; also, one dimension of information literacy can predicted the librarians' job involvement.Conclusion: Information literacy and creativity of librarians of the public libraries of West Azerbaijan province are at a good level and their job involvement is moderate. As librarians' information literacy increases, so does their job involvement and creativity.Value: This study examined the information literacy, creativity and job involvement of librarians as well as the relationship between these variables in a study.
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- 2023
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10. Protocol for virtual physical examination in an observational, longitudinal study evaluating virtual outcome measures in SLE
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Cynthia Aranow, Maria Dall'Era, Meggan Mackay, Diane L Kamen, Wei Tang, Mimi Y Kim, Cristina Arriens, Anca D Askanase, Leila Khalili, and Julia Barasch
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Immunologic diseases. Allergy ,RC581-607 - Abstract
Objective There is a lack of data on the use of telemedicine (TM) in SLE. SLE outcome measures remain complex, and clinicians and clinical trialists have raised concerns about the accuracy of virtual disease activity measures. This study evaluates the level of agreement between virtual SLE outcome measures and face-to-face (F2F) encounter. Here, we describe the study design, virtual physical examination protocol and demographics for the first 50 patients evaluated.Methods and analysis This is an observational, longitudinal study of 200 patients with SLE with varying levels of disease activity from 4 academic lupus centres serving diverse populations. Each study participant will be evaluated at a baseline and a follow-up visit. At each visit, participants are evaluated by the same physician first via a videoconference-based TM and then a F2F encounter. For this protocol, virtual physical examination guidelines relying on physician-directed patient self-examination were established. SLE disease activity measures will be completed immediately after the TM encounter and repeated after the F2F encounter for each visit. The degree of agreement between TM and F2F disease activity measures will be analysed using the Bland-Altman method. An interim analysis is planned after the enrolment of the first 50 participants.Ethics and dissemination This study has been reviewed by the Columbia University Medical Center Institutional Review Board (IRB Protocol #: AAAT6574). The full results of this study will be published after the final data analysis of 200 patients. The abrupt shift to TM visits due to the COVID-19 pandemic disrupted clinical practice and clinical trials. Establishing a high level of agreement between SLE disease activity measures obtained with videoconference TM and F2F at the same time point, will allow for improved assessment of disease activity when F2F data cannot be acquired. This information may guide both medical decision-making and provide reliable outcome measures for clinical research.
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- 2023
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11. Venous thromboembolism: risk of recurrence and long-term anticoagulation
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Leila Khalil, Michael J R Desborough, David Keeling, and Henna Wong
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Adult ,Male ,Venous Thrombosis ,medicine.medical_specialty ,business.industry ,Anticoagulants ,General Medicine ,Middle Aged ,Risk Assessment ,Term (time) ,Decision Support Techniques ,Recurrence ,Neoplasms ,Secondary Prevention ,Medicine ,Initial treatment ,Humans ,Thrombophilia ,Female ,business ,Intensive care medicine ,Pulmonary Embolism ,Venous thromboembolism - Abstract
Recurrence following initial treatment for venous thromboembolism is a significant cause of morbidity and mortality. Balancing the risks of recurrence against the risks of long-term anticoagulation is essential for optimizing patient outcomes.
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- 2015
12. Analyzing Social Engineering Research through Co-authorship Networks Using Scopus Database during 1926-2020
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Leila Khalili and Nayana Darshani Wijayasundara
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bibliometric ,co-authorship networks ,centrality measures ,social engineering ,zipf’s law ,Bibliography. Library science. Information resources ,Communication. Mass media ,P87-96 - Abstract
Purpose: Hacking the human brain and manipulating human trust to obtain information and get monetary gains is called social engineering. This study aims to visualize and analyze the co-authorship networks in the Scopus citation database's social engineering research from 1926 to 2020. Method: The present quantitative study used the bibliometric method and social network analysis. The study collected data from the Scopus database. A total number of 1994 records were taken as the sample of the study. Researchers used descriptive and inferential statistics and social network analysis to obtain results; to do this, different software types were used in the study (SPSS, Microsoft Excel, Text Statistics Analyzer, ISI.exe, Pajek, and VOSviewer). Findings: The findings indicate the top three sources of publishing and the related subject areas. Furthermore, the top three core authors and countries were identified. Also, the authors with high centrality measures in the co-authorship networks were identified. A large majority of papers had only one author. The Collaborative Coefficient among researchers was 0.36. Based on the results of Spearman's test, there was a significant association between the number of documents, the number of citations, and the rate of total link strength of the countries. Likewise, there was a positive and high significant association between degree and closeness centralities. Conclusion: The researchers' frequently used keywords in this area were social engineering, phishing, and information security; in addition, the frequency of keywords was not compatible with Zipf’s Law. A small sample of keywords will not properly follow Zipf’s distribution.
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- 2022
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13. 609 Demographic and clinical factors that contribute to clinical study enrollment
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Anca Askanase, Laura Geraldino-Pardilla, Peter Izmirly, Wei Tang, Leila Khalili, Julia Weiner, Sean Inzerillo, Julia Barasch, Shira Kaplan, Yevgenya Gartshteyn, and Nancyanne Schmidt
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2022
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14. 617 Evaluation of SLE outcome measures in telemedicine: interim analysis results
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Cynthia Aranow, Maria Dall’Era, Mimi Kim, Meggan Mackay, Wei Tang, Cristina Arriens, Anca D Askanase, Leila Khalili, Diane Kamen, and Julia Barasch
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2022
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15. Bibliometric Analysis of Ethics and Technology Research Based on Google Scholar from 1983 to 2020
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Leila Khalili and Abulfzal Ghasemzadeh Alishahi
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collaborative coefficient (cc) ,co-authorship networks ,ethics and technology ,google scholar ,Social Sciences - Abstract
Background: The aim of the present research is to investigate the research outputs on ethics and technology from the perspective of teachers, based on Google Scholar, from 1983 to 2020. Methods: This applied and quantitative study used descriptive and bibliometric methods. The population and sample of the study were 1343 documents retrieved from Google Scholar between 1983 and 2020. Harzing’s Publish or Perish software was used to collect data. VOSviwer and SPSS software were used respectively for visualizing co-authorship network and statistical cases. Results: Based on findings, in the first 16 years only 84 documents were published; the number of publications during the next years steadily increased. About 64% of the papers were written by one author; while only less than 3% of papers had five or six authors. Also, Spearman correlation test showed that there was a significant and positive association between publication year with Google Scholar rank as well as between publication year and the number of authors per paper. The association between publication year and citation per author and publication year with citation was negative and significant. Furthermore, in the present study, the core authors based on co-authorship network and Collaborative Coefficient (CC) were identified. Conclusion: In Google Scholar the new published papers are retrieved and placed in the first ranks. The number of citations per author and number of citations in total increased when the year of publication decreased. It seems the number of published papers is not reason enough to receive higher citation.
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- 2021
16. Searching For Vitamin C, Vitamin D and COVID-19: a Google Trends Study
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Samira Eshginia, Leila Khalili, and Masoumeh Khalili
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covid-19 ,coronavirus ,vitamin c ,vitamin d ,google trends ,Internal medicine ,RC31-1245 - Abstract
ABSTRACT Background and objectives: COVID-19 outbreak is characterized as a pandemic. Owing to the effect of this disease on people’s lives, news about the methods of preventing and treating this disease is released every day. There have been some clinical data suggesting that vitamins C and D can be useful in treating patients with COVID-19 disease. In this study, we aimed to examine vitamin C and D searching trends in 10 countries and worldwide about the COVID-19 news based on the data on Google Trends. Methods: We surveyed the searches about vitamins C and D using some keywords on Google Trends from December 15, 2019 to April 29, 2020. Results: The number of searches increased after the release of news about the effect of vitamins C and D on COVID-19. Conclusion: The results suggest that as the news about the role of vitamins on infection prevention and treatment spreads, people become more interested in expanding their nutritional knowledge.
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- 2021
17. Users Perceptions of Public Library Service Quality Using Gap Analysis Model(LIBQUAL)
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Leila Khalili, Vahideh Dalili, and Aziz Hedayati Khoshemehr
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public libraries ,quality of services ,libqual model ,Information technology ,T58.5-58.64 ,Bibliography. Library science. Information resources ,Management information systems ,T58.6-58.62 - Abstract
The aim of this research is to study the quality of services in the public libraries of Tabriz. This applied research was conducted with a quantitative approach and a survey method. The statistical population of the study was 37931 members of the Public Libraries of Tabriz and the sample size was 380 cases that were selected by stratified random sampling. The data collection tool was the standard LIBQUAL questionnaire and its reliability in the present study based on Cronbach's alpha was 0.93. In order to answer the questions and hypotheses, descriptive and inferential statistics were used using SPSS 24 statistical software. In general, in the three dimensions of LIBQUAL, the average level of minimum expectations of respondents was 4.39, the average level of received services was 5.70 and the average level of maximum expectations was 6.68. The difference between users' expectations and the level of received services in each dimension of the LIBQUAL was not higher than of the maximum expectations. The results of paired t-test confirmed the existence of a significant difference between the maximum expectations and the level of received services by users and also the existence of a significant difference between the minimum expectations and the level of received services by users in all dimensions of the LIBQUAL. It can be concluded that although the libraries have been able to meet the minimum expectations of the users in all cases partly, but the maximum expectations of the users have not been met yet.
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- 2021
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18. Bibliometric Analysis of Worldwide Coronavirus Research based on Web of Science between 1970 and February 2020
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Leila Khalili and M.G. Sreekumar
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centrality measures, co-authorship, coronavirus, density, social network analysis ,Information resources (General) ,ZA3040-5185 ,Transportation and communications ,HE1-9990 - Abstract
Researchers worldwide are striving hard to find a solution for the coronavirus pandemic and reduce the fatalities from this severe outbreak. The purpose of this article is to evaluate and visualize the published documents about coronavirus research, based on extracted data from Web of Science (WoS) citation database. The study used a bibliometric method and social network analysis. Data were collected using the WoS database on February 23, 2020, with 13252 records being retrieved and used as the study sample. Descriptive statistics were used in the bibliometric method and network analysis. Text Statistics Analyzer and ISI.exe were used to compute the number of authors per document. VOSviewer and UCINET were used respectively for visualization and for measuring the centrality and the density of networks. Study findings indicate the top actors of the scientific society (authors, institutions, countries) that had the most publication on coronavirus. Similarly, the top keywords used by authors were identified. Also, the density and centrality measures of co-authorship networks (degree, closeness, betweenness) for the top 10 authors, institutions, countries, and keywords were identified. The Journal of Virology had the highest number of published papers on coronavirus research. The study revealed that the leading researchers and institutions were mostly from the United States of America, England, China, Germany, Netherlands, France, Canada, Japan, South Korea, and Saudi Arabia.
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- 2020
19. The Impact of Telemedicine on Rheumatology Care
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Wei Tang, Sean Inzerillo, Julia Weiner, Leila Khalili, Julia Barasch, Yevgeniya Gartshteyn, Maria Dall'Era, Cynthia Aranow, Meggan Mackay, and Anca Askanase
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autoimmune diseases (AD) ,telemedicine ,quality of life ,quality of care/care delivery ,survey ,telerheumatology ,Medicine (General) ,R5-920 - Abstract
BackgroundThe pandemic disrupted the care of patients with rheumatic diseases; difficulties in access to care and its psychological impact affected quality of life. Telemedicine as an alternative to traditional face-to-face office visits has the potential to mitigate this impact.ObjectiveTo evaluate patient and provider experience with telemedicine and its effect on care.MethodsWe surveyed patients with rheumatic diseases and their rheumatology providers. The surveys were conducted in 2020 and repeated in 2021. We assessed data on quality of care and health-related quality of life.ResultsHundred patients and 17 providers responded to the survey. Patients reported higher satisfaction with telemedicine in 2021 compared to 2020 (94 vs. 84%), felt more comfortable with (96 vs. 86%), expressed a stronger preference for (22 vs. 16%), and higher intention to use telemedicine in the future (83 vs. 77%); patients thought physicians were able to address their concerns. While providers' satisfaction with telemedicine increased (18–76%), 14/17 providers believed that telemedicine visits were worse than in-person visits. There were no differences in annualized office visits and admissions. Mean EQ-5D score was 0.74, lower than general population (0.87) but equivalent to a subset of patients with SLE (0.74).ConclusionOur data showed a high level of satisfaction with telemedicine. The lower rheumatology provider satisfaction raises concern if telemedicine constitutes an acceptable alternative to in-person care. The stable number of office visits, admissions, and the similar quality of life to pre-pandemic level suggest effective management of rheumatic diseases using telemedicine/in-person hybrid care.
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- 2022
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20. Nuts as a Part of Dietary Strategy to Improve Metabolic Biomarkers: A Narrative Review
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Leila Khalili, Thoraya Mohamed Elhassan A-Elgadir, Ayaz Khurram Mallick, Hesham Ali El Enshasy, and R. Z. Sayyed
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lipid profile ,oxidative stress ,glycemic control (A1C) ,metabolic biomarkers ,inflammation ,Nutrition. Foods and food supply ,TX341-641 - Abstract
BackgroundNuts are in the spotlight because of their association with improved health outcomes. We aimed to summarize the findings of previous studies to evaluate the impact of nuts consumption on glycaemic and lipid profile, inflammation, and oxidative stress.MethodsElectronic searches for observational and intervention studies were undertaken in PubMed, Embase, Web of Science, and Science Direct until 2022 for searching the studies aiming the application of different types of nuts and the beneficial effects of nuts in improving glycemia, dyslipidemia, inflammation, and oxidative stress.ResultsResults from 56 interventional, 9 narrative and 3 systematic reviews, and 12 meta-analysis studies, aiming at the evaluating beneficial effects of different types of nuts on metabolic markers, showed that nut consumption could improve metabolic markers, including glycaemic factors, lipid profile, and inflammatory and oxidative stress parameters in both healthy and individuals with metabolic disorders in a type-, dose- and duration-dependent manner. According to their unique nutrient components, nuts can be known as a part of a healthy diet, resulting in improved metabolic biomarkers.ConclusionConsidering the efficacy of nuts in improving metabolic markers, incorporation of, incorporating nuts the effectiveness of nuts in improving metabolic markers, incorporating nuts in the diet may prevent the incidence or aggravation of chronic metabolic diseases. Considering the health benefits of the nuts' components, including essential micronutrients, if consumed in the appropriate dose and duration to provide the necessary amount of effective micronutrients to improve health, we will see an improvement in metabolic factors. At the same time, more research is required to determine the optimal type, dose, and duration of nut intervention with regards to metabolic control and reducing the risk of developing metabolic disorders.
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- 2022
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21. Retraction Note: Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial
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Leila Khalili, Beitullah Alipour, Mohammad Asghari Jafarabadi, Tohid Hassanalilou, Mehran Mesgari Abbasi, and Ismail Faraji
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Nutritional diseases. Deficiency diseases ,RC620-627 - Published
- 2023
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22. The role of student government in colleges with particular reference to Beirut College for Women. (c1965)
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Khoury, Leila Khalil and Khoury, Leila Khalil
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- 2012
23. 1105 Telemedicine in rheumatology: a survey of patient and provider satisfaction with virtual care
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Maria Dall’Era, Anca Askanase, Meggan Mackay, and Leila Khalili
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2021
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24. 1108 Frequency-domain optical imaging can diagnose lupus arthritis
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Anca Askanase, Leila Khalili, Alessandro Marone, and Andreas Hielscher
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Immunologic diseases. Allergy ,RC581-607 - Published
- 2021
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25. The role of student government in colleges with particular reference to Beirut College for Women. (c1965)
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Khoury, Leila Khalil, primary
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26. Effect of L. acidophilus and B. lactis on blood glucose in women with gestational diabetes mellitus: a randomized placebo-controlled trial
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Farnaz Sahhaf Ebrahimi, Aziz Homayouni Rad, Metanat Mosen, Fatemeh Abbasalizadeh, Aydin Tabrizi, and Leila Khalili
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Gestational diabetes mellitus ,Probiotic ,Yoghurt ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background Gestational diabetes mellitus (GDM) is a complication of pregnancy that can be associated with neonatal complications and adverse pregnancy outcomes. Recently, probiotic use has been proposed for better control of glucose in GDM patients. The aim of this study was to evaluate the effect of probiotic yoghurt compare with ordinary yoghurt on GDM women. Methods In this double-blind placebo-controlled clinical trial, 84 pregnant women with GDM were randomly assigned into two groups of 42 recipients who underwent 300 g/day of probiotic yoghurt or placebo for 8 weeks. Blood glucose, HbA1c, and the outcome of pregnancy were compared between the two groups after the intervention. Results According to the findings of present trial no significant differences were observed in general characteristics between the two groups (p > 0.05). Both fasting and post prandial blood glucose as well as the level of HbA1c were decreased significantly in probiotic group (p
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- 2019
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27. Challenges and Approaches Towards Attracting New- literate Adults to the Public LibrariesCase Study of Azarshahr
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Afsaneh Abbasi, Faegheh Mohammadi, Leila Khalili, and Torab Najjari
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public libraries ,education ,new-literates ,challenges & approaches ,azarshahr-public libraries ,Information technology ,T58.5-58.64 ,Bibliography. Library science. Information resources ,Management information systems ,T58.6-58.62 - Abstract
The purpose of this study is to identify challenges and providing approaches towards attracting new- literate adults to the public libraries from the librarians’ perspectives. The method is qualitative exploratory case study. The population is public librarians and the sample are 14 librarians employed in public libraries of the city of Azarshahr. Using purposive sampling data were gathered by semi-structured interviews and were analyzed using Glasser & Strauss’ Coding Technique. The participants of this research disclosed some major challenges towards attracting new literate adults to the public libraries including individual, social, physical, publishing and organizational challenges. Also The participants suggested some approaches to deal with the challenges such as cultural advertising, providing further support and facilities for the new literates by the public libraries and library cooperation with the other organizations. Applying the findings of this study would enable the public libraries to provide suitable services with the aim of attracting more new literate users to the public libraries.
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- 2019
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28. SARS-CoV-2 vaccines in patients with SLE
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Joan T Merrill, Wei Tang, Anca D Askanase, and Leila Khalili
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Immunologic diseases. Allergy ,RC581-607 - Abstract
As the Moderna (mRNA-1273) and Pfizer/BioNTech (BNT162b2) vaccines become available to patients with autoimmune diseases and SLE, practitioners will have to inform them about the safety and efficacy of these vaccines. Here we discuss the challenges of applying vaccine data to patients with autoimmune diseases and the evidence available in the literature that may help in the decision process.
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- 2021
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29. Evaluation of SLE arthritis using frequency domain optical imaging
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Hyun Kim, Wei Tang, Yevgeniya Gartshteyn, George Danias, Anca D Askanase, Leila Khalili, Cathy Guo, Youngwan Kim, Alessandro Marone, Tommy Chen, and Andreas Hielscher
- Subjects
Immunologic diseases. Allergy ,RC581-607 - Abstract
Objectives Systemic lupus erythematosus (SLE) affects the joints in up to 95% of patients. The diagnosis and evaluation of SLE arthritis remain challenging in both practice and clinical trials. Frequency domain optical imaging (FDOI) has been previously used to assess joint involvement in inflammatory arthritis. The objective of this study was to evaluate FDOI in SLE arthritis.Methods Ninety-six proximal interphalangeal (PIP) joints from 16 patients with SLE arthritis and 60 PIP joints from 10 age-matched, gender-matched and race/ethnicity-matched controls were examined. A laser beam with a wavelength of 670 nm, 1 mm in diameter and intensity modulated at 300 MHz and 600 MHz was directed onto the dorsal surface of each joint, scanning across a sagittal plane. The transmitted light intensities and phase shifts were measured with an intensified charge-coupled device camera. The data were analysed using Discriminant Analysis and Support Vector Machine algorithms.Results The amplitude and phase of the transmitted light were significantly different between SLE and control PIPs (p
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- 2021
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30. Rheumatologists’ perspective on hydroxychloroquine guidelines
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Anca D Askanase, Leila Khalili, James Winebrake, Julia Weiner, and Lisa Park
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Immunologic diseases. Allergy ,RC581-607 - Abstract
Objective Hydroxychloroquine (HCQ) retinal toxicity is an ongoing concern for rheumatologists. The revised 2016 American Academy of Ophthalmology (AAO) guidelines created controversy regarding the correct dosing and evaluation of HCQ toxicity. The current study was initiated to further understand rheumatologists’ practices regarding HCQ.Methods A questionnaire-based survey was distributed electronically to rheumatologists. We collected information on HCQ dosing, clinical decision-making processes, familiarity with the AAO 2016 guidelines, and perceived disparities between the AAO 2016 guidelines and rheumatological clinical practice.Results 78 rheumatologists completed the survey (49% from USA, 90% academic practices, 82% self-identified as lupus experts). Only lupus expert (n=64) data were included in subsequent analysis. The mean cohort size was 747 (50–6571), a total cohort 45 612 patients. HCQ was prescribed to >75% of patients with SLE by 81.3% of SLE experts, with routine counselling about ophthalmic risks. The typical dose of HCQ used was 200–400 mg/day. 17% of rheumatologists use doses up to 600 mg/day, while 6.2% use up to 6.5 mg/kg/day. HCQ adherence is routinely assessed. 479 cases of HCQ retinal toxicity (1.05%) and 9 cases of HCQ-associated blindness (1.8 per 10 000 patients) were reported. 89.1% of respondents reported familiarity with the AAO guidelines. Those aware of the guidelines cited limited dosing options (54.7%), lack of supporting evidence (57.8%) and low patient adherence (43.8%) as obstacles to greater implementation of the guidelines.Conclusion These data suggest that HCQ toxicity and blindness are rare in patients with SLE. Rheumatologists treating patients with SLE are aware of the guidelines and appreciate the importance of partnering with ophthalmologists in preventing retinal toxicity.
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- 2020
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31. Thoughts on COVID-19 and autoimmune diseases
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Jill P Buyon, Anca D Askanase, and Leila Khalili
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Immunologic diseases. Allergy ,RC581-607 - Abstract
Over the 2 months since coronavirus first appeared in China, cases have emerged on every continent, and it is clear that patients with autoimmune diseases might also be affected. Coronavirus disease 2019 (COVID-19) is a highly contagious viral illness with a mortality rate approaching 2%. Here we discuss the challenges that patients with autoimmune diseases might face and the information on using immunomodulatory therapies like chloroquine, tocilizumab and baricitinib to quench the cytokine storm in patients with very severe COVID-19 pneumonia.
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- 2020
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32. Probiotic assisted weight management as a main factor for glycemic control in patients with type 2 diabetes: a randomized controlled trial
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Leila Khalili, Beitullah Alipour, Mohammad Asghari Jafarabadi, Tohid Hassanalilou, Mehran Mesgari Abbasi, and Ismail Faraji
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Lactobacillus casei ,Type 2 diabetes mellitus ,Body weight ,Dietary intake ,Glycemic control ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Objectives To evaluate the effect of Lactobacillus casei 01 on dietary intake, body weight, and glycemic control in patients with T2DM. Method Forty patients with T2DM (n = 20 for each group) were assigned into two groups in present trial. The patients in the probiotic group received a daily capsule containing a minimum of 108 CFU of L. casei 01 for 8 week. The placebo group took capsules filled with maltodextrin for the same time period. Dietary intake questionnaires and anthropometric measurements were collected, and the participants were assessed by an endocrinologist at baseline and at the end of the trial. Results Lactobacillus casei 01 supplementation significantly decreased total energy, carbohydrate, fat, and protein intake compared with placebo (p = 0.001, p = 0.002, p = 0.009, p = 0.001; respectively). Moreover weight, BMI, and waist circumference were significantly decreased in intervention group compared with placebo group (p
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- 2019
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33. Dependency of University students on Social Networks Based on Demographic Variables
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Leila Khalili and Faegheh Mohammadi
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dependency ,social networks ,azarbaijan shahid madani university ,demographic variables ,undergraduate student ,Information technology ,T58.5-58.64 ,Bibliography. Library science. Information resources ,Management information systems ,T58.6-58.62 - Abstract
The aim of this research is to study the dependency of students on social networks based on demographic variables. This applied and quantitative research carried out in survey design. The measurement tool for the study was a social networks addiction subscale adopted from questionnaire of Arslan & Kırık (2013). The reliability of tool based on Cronbach's alpha was 0.932. The content validity of tool was measured by view of specialist and construct validity was measured by factor analysis. The population of the study was 4771 undergraduate students at Azarbaijan Shahid Madani University and the sample size was 368 cases based on stratified random sampling method. SPSS software was used in descriptive and inferential statistics. Based on Pearson correlation test, the relationship between students’ dependency on social networks and Internet/social network rate of usage at 99 percent confidence level was positive and significant. Based on independent t-test, there was a significant difference in students’ social network dependency based on accommodation type. Based on ANOVA test, there was significant difference at 95 percent confidence level based on domain of study. Students’ dependency on social networks was in midpoint level. The students, who had further daily Internet or social network usage, had more dependency on networks. Students’ dependency on social networks with different levels of academic achievement was moderately similar. Dependency on social networks among two groups of students (dormitory/humanities domain) was more.
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- 2019
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34. Effect of n-3 (Omega-3) Polyunsaturated Fatty Acid Supplementation on Metabolic and Inflammatory Biomarkers and Body Weight in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of RCTs
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Leila Khalili, Roxana Valdes-Ramos, and Laurence S. Harbige
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meta-analysis ,n-3 ,polyunsaturated fatty acids PUFA ,T2DM ,diabetes ,randomized controlled trials RCTs ,Microbiology ,QR1-502 - Abstract
Beneficial effects of n-3 fatty acids on metabolic biomarkers in patients with type 2 diabetes (T2DM) has been reported. The objectives of this current research were to investigate the effects of n-3 supplementation on metabolic factors, weight, and body mass index (BMI) in patients with type 2 diabetes mellitus (T2DM), using a meta-analysis of randomized, controlled trials (RCTs). Online databases PubMed, Embase, Web of Science, and Science Direct were searched until 2021 to identify eligible articles. Thirty trials were included. The results showed that n-3 consumption can significantly reduce glycemic factors including fasting blood sugar (FBS) (−0.36 (−0.71 to −0.01)), glycated hemoglobulin (HbA1c) (−0.74 (−1.13 to −0.35)), and homeostatic model assessment of insulin resistance (HOMA.IR) (−0.58 (−1.13 to −0.03)). Furthermore, significant improvement in lipid profile including triglycerides (TG) (−0.27 (−0.37 to −0.18)), total cholesterol (−0.60 (−0.88 to −0.32)), low density lipoprotein (LDL) (−0.54 (−0.85 to −0.23)), and high-density lipoprotein (HDL) (0.60 (0.23 to 0.96)) levels were found in the present meta-analysis. The reduction in the inflammatory marker’s tumor necrosis factor-alpha (TNF-α) (−0.13 (−0.75 to 0.48)) and c-reactive protein (CRP) (−0.72 (−1.70 to 0.27)), as well as weight (−0.09 (−0.24 to 0.07)) and BMI (−0.13 (−0.29 to 0.02)) were not statistically significant. Furthermore, the findings revealed that the optimal dose and duration of n-3 consumption for patients with T2DM is 1000–2000 mg/d for more than 8 weeks. The present meta-analysis and review reveals that n-3 supplementation can improve glycemic factors and lipid profile in patients with T2DM. Furthermore, n-3 supplementation may provide beneficial effects on inflammatory markers and body weight if used at the appropriate dose and duration.
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- 2021
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35. Participation of Iranian Medical Universities in ResearchGate
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Leila Khalili
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Universities ,Social Networks ,ResearchGate ,Scientometrics ,Altmetrics ,Co-authorship ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Introduction: ReseachGate network provides an opportunity for scientific collaboration between researchers in process of knowledge production. This study investigated the situation of Iranian medical universities in ReseachGate. Methods: This applied and quantitative study used a scientometric method (altmetrics). Population of the study was 45 Iranian medical universities present in ReseachGate. Data collection was carried out from 27 April until 21 June 2015 by means of manual observation and recording information from ReseachGate, webometric and Islamic World Science Citation Center (ISC) websites. Spearman coefficient was used to test the correlation between variables. SPSS17 software was used for data analysis and Pajak software for drawing the related graphs. Results: Medical universities of Tehran, Shahid Behesti, Shiraz, Mashhad, Isfahan and Tabriz had the highest ReseachGate scores, respectively. United State of America, China and Iran respectively had the most view and download of Iranian medical documents (papers) in ReseachGate. Tehran University of Medical Sciences had a central role in co-authorship with majority of Iranian medical universities. Finally, there was a strong and positive correlation between ReseachGate score and ranking of medical universities in ISC and webometics. Conclusion: The results showed that the higher ranking universities are more active in ReseachGate. Tehran University of Medical Sciences is the most important node of co-authorship network. Geographical closeness is influential in co-authorship.
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- 2016
36. Barriers to Publish in Open Access Journals According to Medical researchers
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Leila Khalili
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Universities ,Open Access to Information ,Periodicals ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Introduction: The Open Access Movement has been one of the best ways that can facilitate information flow. One of the representations of the Open Access Movement is Open Access Journals. Despite the positive attitudes of the scientific community towards Open Access Journals, it seems that the number of the researchers who have the tendency to publish in these journals as compared with Closed Access Journals has been limited. The purpose of this study was to investigate the views of medical researchers as to the barriers to publishing papers in Open Access Journals. Methods: This applied study used a survey design. Population of the study was academic staff of Medicine Schools in Public Medical Universities of Iran and the sample size was 367 respondents. This study was carried out in 2009-2012. Data collection instrument was a questionnaire developed by researcher of the study. The reliability of twelve items of this study was estimated by using Cronbach's alpha whose coefficient was 0.859. The validity of questions was assessed by using Test-retest among population of the study and experts' view on open access area. In order to analysis date in descriptive level, percent and mean was used. In inferential level, Pearson correlation coefficient was used. SPSS 17 was used to analysis data. Results: Based on the findings, with a total of 76 percent of respondents, author-charge was a barrier to publishing papers in Open Access Journals. According to majority of the respondents, negative influence of publishing papers in open access journals on career promotion as well as problem of renewing credit card were not important publishing barriers. Based on Pearson correlation coefficient, there was a significant relation (r=-0.130, p=0.05) between publishing experience and publishing barriers. Conclusion: Among the all mentioned barriers, author-charge is the most important reason for not publishing in valid Open Access Journals. However, the increase of publishing experience of respondents can reduce the influence of barriers significantly.
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- 2015
37. Reference Librarian in Digital Environment
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Faramarz Sohili and Leila Khalili
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Reference Librarian ,Digital Reference Services ,Professional Ethics ,Moral Traits ,Bibliography. Library science. Information resources - Abstract
The information explosion of the latter half of the twentieth century, gave rise to online databases and various information media that gradually impacted on the very physical environment of the library. It transformed the librarians’ role. Reference librarians are no exception. The present study aims to investigate the need or lack of need to reference librarians within the digital domains based on the views expressed by LIS authorities in Iran. It would attempt further, to identify the qualities required for such librarian should a need for her/his expressed. The research, while descriptive in nature, was based on analyzing the results obtained by the checklist devised by the authors. LIS Specialist sample was composed of 57 people who filled the checklist. Findings show that there is a significance between employing ICT and need for a reference librarian. LIS experts in Iran believe that introduction of ICT, especially Internet and the WWW not only didn’t decrease the need for such librarians, but has caused the reference librarian to attain a more important and better status than before. Findings further demonstrated that while Iran is not a signatory to the international copyright conventions, the Iranian reference librarians are fully committed to observing author’s copyright and intellectual rights and frown on using software crackers.
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- 2008
38. Evaluation of Diagnostic Visual Findings at Laparoscopy in Endometriosis
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Saghar Salehpour, Hanieh Zhaam, Mahnaz Hakimifard, Leila Khalili, and Yaedollah Azar Gashb
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endometriosis diagnosis ,laparoscopy ,histopathology ,Medicine (General) ,R5-920 - Abstract
Background Endometriosis has been widely implicated as one of the causes of chronic pelvic pain, dysmenorrhea and infertility. The purpose of our study was to define the presumed correlation between visual and histologic diagnostic features of endometriosis based on the peritoneal findings identified in laparoscopy as a diagnostic trial with a standardized technique. So, all the specimens including complete excised lesions suggestive of endometriosis and systematic biopsies of normal appearing pelvic peritoneum were analyzed. This study was performed in Mahdieh hospital and IRHRC1 .between 2004 and 2005. Materials and methods A diagnostic study of 30 patients (14 to 45 years) undergoing diagnostic laparoscopy for the evaluation of chronic pelvic pain, infertility, dysmenorrhea and dyspareunia .(was carried out (average age was 28.6±5.14 All areas suggestive of endometriosis were excised and examined pathologically. Peritoneal biopsy specimens were obtained from areas of normal appearing peritoneum to rule out .microscopic endometriosis The positive predictive value, sensitivity, negative predictive value and specificity were .determined for identified endometriosis versus the histological findings . Results The mean prevalence of abnormalities visually consistent with endometriosis was 63% while 42% confirmed histologically. The positive predictive value was 42.1%, sensitivity 88.8%, negative predictive 90.9% and specificity 47.6% for visual versus histological diagnosis .of endometriosis. Conclusion A diagnosis of endometriosis should be established only after histologic confirmation.
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- 2007
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39. The Relationship between Study Approaches and the Use of Virtual Social Networks among University Students
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Leila Khalili, Fatemeh Alirezay Laki, and Rahim Shahbazi
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deep study approach ,surface study approach ,strategic study approach ,use of virtual social networks ,Bibliography. Library science. Information resources - Abstract
Purpose: The main objective of this research is to examine the correlation between study approaches and the frequency of virtual social network usage among university students.Methodology: This study utilized a quantitative approach and survey method to gather data from 276 students at Azarbaijan Shahid Madani University. Two questionnaires were employed, with reliabilities confirmed using Cronbach's alpha coefficient. Data analysis was conducted at both descriptive and inferential levels using SPSS software.Findings: The average virtual network usage was 3.80, while deep, strategic, and superficial study approaches scored 3.82, 3.91, and 3.20 respectively. Pearson correlation revealed a positive relationship between superficial study approach and virtual network usage, while a negative correlation was found with deep and strategic approaches. Significant relationships were noted between GPA and virtual network usage (negative), GPA and deep/strategic approaches (positive), and GPA and surface approach (negative). Only the strategic approach showed a negative predictive power with a beta coefficient of -0.32.Conclusion: The predominant study approach among students was strategic. Increased virtual network usage was associated with a decrease in strategic and deep approaches. Students adopting strategic and deep approaches exhibited better academic performance.Value: This study aims to bridge the gap in research on the use of new media and its impact on students' study approaches.
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- 2000
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