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Additional file 1: Figure S1 Characterization of ZON. A, B ZON was synthesized and the actual size and surface charge were observed by TEM and zeta potential analyzer. Figure S2 Effect of ZON on HcerEpic cells. A HcerEpic cells were treated with ZON. The cell growth was analyzed by colony formation assays. Ns no significant. Figure S3 ZON inhibits cell growth of cervical cancer in vivo by targeting CD164. A–D Tumor growth of Hela cell was analyzed by xenograft mouse model in vivo (n=5). The tumor images (A), tumor weight (B), Ki-67 levels (C), and CD164 expression (D) were shown. The experiments were repeated 3 times, **P < 0.01.