1. Lung Luminescence: Unravelling the tapestry of Cancer Cases by Bronchoscopic biopsies in Tertiary Care Hospital.
- Author
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Afzal, Muhammad Waqas, Ul Mannan, Muhammad Atiq, Shehzad, Muhammad, Riaz, Muhammad Waseem, Atif, Muhammad, and Muzammil, Muhammad
- Subjects
TREATMENT of lung tumors ,BIOPSY ,CROSS-sectional method ,SQUAMOUS cell carcinoma ,STATISTICAL sampling ,SMOKING ,EARLY detection of cancer ,LUNGS ,TERTIARY care ,RETROSPECTIVE studies ,DESCRIPTIVE statistics ,LUNG tumors ,MEDICAL records ,ACQUISITION of data ,BRONCHOSCOPY ,DATA analysis software ,SMALL cell carcinoma - Abstract
Background: Lung cancer, often diagnosed late, is a leading cause of death worldwide. Bronchoscopic biopsies are crucial for early detection, especially in smokers. In Pakistan, where smoking is prevalent, understanding lung cancer patterns is essential. This study examines the types and locations of lung cancers diagnosed via bronchoscopic biopsies in a tertiary care hospital, providing insights for better diagnosis and treatment. Objectives: To determine the prevalence of different types of lung malignancies by using bronchoscopic guided endobronchial biopsies. Methodology: It was a retrospective cross-sectional study conducted in in-patient of Department of Pulmonology, department Nishtar Medical University Multan study of 43 patients enrolled between June 2022 to Oct 2023 by using consecutive non probability sampling method. All were smokers more than 20 pack year. Data analysis was done by using SPSS 23 version. Results: Out of 43 patients 34 (79%) were male and 9 (21%) were female. Bronchoscopic biopsy result showed small cell carcinoma being the most common tumour in our study 15 (34.88%) cases followed by Squamous cell carcinoma 14 (32.55%), Adenocarcinoma 6(13.95%), invasive carcinoma with hepatoid features 1 (2.32%), carcinoid tumour 1(2.32%), organizing Pneumonia 1(2.32%) and in biopsy was inconclusive in 5 (11.62%) cases. Tumour involvement by the location was also assessed in the present study. Most common site of origin was found to be Left main bronchus 11 (25.58%) followed by Right Main bronchus 9 (20.93%), Left upper lobe 9 (20.93%), Right upper lobe 5(11.62%), Left lower lobe 4 (9.30%), Lingular lobe 3 (6.97%), Right lower lobe 2(0.86%). Conclusion: This study revealed that small cell carcinoma is the most prevalent type of lung cancer diagnosed via bronchoscopic biopsies among smokers with over 20 pack-years of smoking history. These findings highlight the critical role of bronchoscopic biopsies in the early detection of lung cancer in high-risk populations, underlining the need for targeted screening and tailored treatment approaches to improve patient outcomes in regions with high smoking prevalence. [ABSTRACT FROM AUTHOR]
- Published
- 2024