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8. Effects of Participation into Rehabilitation Exercise on the Change of Health Fitness in the Elderly with Hemiplegia

Author

Lee Jong Sam, Kim， Yong-Kyu, Hur Sung Hoon, and An Kyung Jun

Subjects
medicine.medical_specialty, Physical disability, Blood pressure, business.industry, Rehabilitation exercise, Statistical significance, Physical fitness, Physical therapy, Elderly people, Medicine, Dynamic balance, Physical strength, business
Abstract

Purpose: The purpose of this study is to analyze the effects of participation into rehabilitation exercise on the change of health fitness in the elderly with hemiplegia. Methods: The subjects of this study were 6 elderly people with hemipgleia physical disability who participated in the rehabilitation exercise program in the province o fK. Before and after 12 weeks (once a week and 60 minutes exercise) of rehabilitation exercise program weer analysed in change of basic physical fitness (muscular strength and muscular endurance, dynamic balance, flexibility and cardiopulmonary endurance) and medical examination (systolic and diastolic blood pressure andb lood glucose). The results were analyzed by frequency analysis and independent t-test using Windows SPSS 2.00. All statistical significance levels were set to α=.05. The following conclusions were obtained. Results: The results of this study are as follows. 1) Rehabilitation exercise program was not able to improve the basic physical fitness tests (muscular strength and muscula r endurance, flexibility, dynamic balance, and cardiopulmonary endurance) of the elderly with hemiplegia physical disability. 2) Rehabilitation exercise program showed a positive change due to a decrease in systolic blood pressure of the elderly with hemiplegia physical disability, but did not lead to a positive change in medical examination (diastolic blood pressure and blood glucose). Conclusion: In a follow-up study, when more frequent exercise is performed compared to one week’s exercise in this study, and more subjects is selected to make ao cmparison between the non-disabled and the hemiplegic disabled, it will provide important background material that can emphasize the need for rehabilitation exercise programs.

Published
2019

18. The Investigation of AMPK and MAPK Protein Expression in Human Deltoid and Vastus Lateralis Muscle During 100m and 1500m Time Trial Swimming

Author

Lee Byung Doo, Lee Jong Sam, kim hyosik, choi kangjin, and youk hyeon chel

Subjects
MAPK/ERK pathway, medicine.medical_specialty, Swimming exercise, Vastus lateralis muscle, business.industry, p38 mitogen-activated protein kinases, Deltoid curve, AMPK, Anatomy, Protein expression, Time trial, Endocrinology, Internal medicine, medicine, business
Published
2012

23. The Comparison of Plasma Volume and Fluid Regulatory Hormones during Submaximal Exercise between Athletes and Non-athletes of Similar Body Composition

Author

YounSoo Jung, Park，Sung-Han, Yoo， Ho Sang, Kim，Jin-Hyung, Lee Jong Sam, and Yeung Woo Kwon

Subjects
medicine.medical_specialty, Aldosterone, biology, business.industry, Athletes, Submaximal exercise, biology.organism_classification, Plasma volume, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Renin–angiotensin system, Medicine, business, Hormone
Published
2010

24. The influence of dietary feeding type and acute exercise on gene expression of PPAR isoforms in skeletal muscle

Author

Sung-Han Park, Jung-Kyu Kim, Lee Jong-Sam, Hee-won Moon, and Jangkyu Lee

Subjects
chemistry.chemical_classification, Gene isoform, medicine.medical_specialty, Chemistry, Public Health, Environmental and Occupational Health, Peroxisome proliferator-activated receptor, Skeletal muscle, Physical Therapy, Sports Therapy and Rehabilitation, Endocrinology, medicine.anatomical_structure, Physiology (medical), Internal medicine, Gene expression, medicine
Published
2008

32. The effect of exercise on the skeletal muscle phospholipidome of rats fed a high-fat diet

Author

Mitchell, Todd W, Turner, N., Else, Paul, Hulbert, Anthony J, Hawley, John, Lee, Jong Sam, Bruce, Clinton, Blanksby, Stephen J., Mitchell, Todd W, Turner, N., Else, Paul, Hulbert, Anthony J, Hawley, John, Lee, Jong Sam, Bruce, Clinton, and Blanksby, Stephen J.

Abstract

The aim of this study was to examine the effect of endurance training on skeletal muscle phospholipid molecular species from high-fat fed rats. Twelve female Sprague- Dawley rats were fed a high-fat diet (78.1% energy). The rats were randomly divided into two groups, a sedentary control group and a trained group (125 min of treadmill running at 8 m/min, 4 days/wk for 4 weeks). Forty-eight hours after their last training bout phospholipids were extracted from the red and white vastus lateralis and analyzed by electrospray-ionization mass spectrometry. Exercise training was associated with significant alterations in the relative abundance of a number of phospholipid molecular species. These changes were more prominent in red vastus lateralis than white vastus lateralis. The largest observed change was an increase of ~30% in the abundance of 1-palmitoyl-2-linoleoyl phosphatidylcholine ions in oxidative fibers. Reductions in the relative abundance of a number of phospholipids containing long-chain n-3 polyunsaturated fatty acids were also observed. These data suggest a possible reduction in phospholipid remodeling in the trained animals. This results in a decrease in the phospholipid n-3 to n-6 ratio that may in turn influence endurance capacity.

Published
2010

36. Dietary regulation of fat oxidative gene expression in different skeletal musle fiber types

Author

McAinch, Andrew, Lee, Jong-Sam, Bruce, Clinton, Tunstall, Rebecca, Hawley, John, Cameron-Smith, David, McAinch, Andrew, Lee, Jong-Sam, Bruce, Clinton, Tunstall, Rebecca, Hawley, John, and Cameron-Smith, David

Abstract

Objective: To determine the effect of a high-fat diet on the expression of genes important for fat oxidation, the protein abundance of the transcription factors peroxisome proliferator-activated receptor (PPAR) isoforms α and γ, and selected enzyme activities in type I and II skeletal muscle. Research Methods and Procedures: Sprague-Dawley rats consumed either a high-fat (HF: 78% energy, n = 8) or high-carbohydrate (64% energy, n = 8) diet for 8 weeks while remaining sedentary. Results: The expression of genes important for fat oxidation tended to increase in both type I (soleus) and type II (extensor digitorum longus) fiber types after an HF dietary intervention. However, the expression of muscle type carnitine palmitoyltransferase I was not increased in extensor digitorum longus. Analysis of the gene expression of both peroxisome proliferator-activated receptor-γ coactivator and forkhead transcription factor O1 demonstrated no alteration in response to the HF diet. Similarly, PPARα and PPARγ protein levels were also not altered by the HF diet. Discussion: An HF diet increased the expression of an array of genes involved in lipid metabolism, with only subtle differences evident in the response within differing skeletal muscle fiber types. Despite changes in gene expression, there were no effects of diet on peroxisome proliferator-activated receptor-gamma coactivator and forkhead transcription factor O1 mRNA and the protein abundance of PPARα and PPARγ.

Published
2003

50. Effect of L-carnitine supplementation and aerobic training on FABPc content and beta-HAD activity in human skeletal muscle.

Author

Lee, Jang Kyu, Lee, Jong Sam, Park, Hyon, Cha, Youn-Soo, Yoon, Chung Su, and Kim, Chang Keun

Subjects
*CARNITINE, *CARRIER proteins, *COMPARATIVE studies, *DIETARY supplements, *EXERCISE, *GENETIC disorders, *LIPID metabolism disorders, *RESEARCH methodology, *MEDICAL cooperation, *MUSCLES, *OXIDOREDUCTASES, *PHYSICAL fitness, *RESEARCH, *STATISTICAL sampling, *TIME, *PHENOTYPES, *EVALUATION research, *RANDOMIZED controlled trials, *SKELETAL muscle
Abstract

Both regular physical exercise and carnitine supplementation exert a role in energy metabolism and may improve endurance capacity. We investigated whether a combination of long-term carnitine ingestion and exercise training reveals any interactive effects on cytosolic fatty acid-binding protein (FABPc) expression and beta-hydroxyacyl CoA dehydrogenase (beta-HAD) activity in human skeletal muscle. Twenty-eight untrained healthy males randomly divided into four experimental groups: a placebo (CON; n = 7), exercise training (ET; n = 7, 40 min session(-1), five times per week at 60% VO2max), carnitine supplementation (CS; n = 7, 4 g day(-1)), and exercise training and carnitine supplementation (CT; n = 7). Before and after 6-week treatment, muscle biopsy samples were taken from the vastus lateralis. Nonesterified carnitine and acid-soluble acylcarnitine concentrations were increased in CT (P < 0.05), and serum triacylglycerol concentration was elevated almost twofold in ET and CT (P < 0.05). No interactive effects in FABPc expression were shown from any of treatment groups. Although FABPc increased by 54% in ET compared to CON, it failed to reach statistical significance. In addition, there was no change in FABPc expression from any of experimental groups. Similar trends with FABPc contents were demonstrated in beta-HAD activity. It is concluded that the combination of exercise training and L-carnitine supplementation does not augment in FABPc expression and beta-HAD activity in human skeletal muscle indicating that combined treatment does not exert additive effect in fat metabolism. Thus L-carnitine supplementation would be unlikely to be associated with the enhanced exercise performance. [ABSTRACT FROM AUTHOR]

Published
2007

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