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3. Demonstration of a population-based HCV serosurvey in Ho Chi Minh City, Viet Nam: Establishing baseline prevalence of and continuum of care for HCV micro-elimination by 2030

Author

Kim, Thanh V, Le, Duc H, Dao, Diem VB, Pham, Trang Ngoc Doan, Mize, Gary W, Phan, Loc TB, Nguyen, Dan X, Ngo, Thi-Thuy-Dung, Gish, Robert G, Lee, William M, Trang, Amy, Le, Anh N, Chen, Moon, Phan, Hai T, Nguyen, Binh T, Tang, Hong K, and Dao, Doan Y

Subjects
Biomedical and Clinical Sciences, Public Health, Health Sciences, Infectious Diseases, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Hepatitis - C, Clinical Research, Emerging Infectious Diseases, Hepatitis, Good Health and Well Being, Hepatitis C virus, Ho Chi Minh City, Viet Nam, Framework, Micro-elimination, National elimi-nation, 2030, Access to care, HCV screening, HCV baseline linkage to care, National elimination, Clinical sciences, Health services and systems, Public health
Abstract

BackgroundA baseline of hepatitis C virus (HCV) burden and other HCV epidemiological profiles is necessary for HCV micro-elimination in Ho Chi Minh City (HCMC), Viet Nam. This study aimed to determine HCV exposure and prevalence of HCV viremia as well as the proportion of HCV testing and treatment uptake among participants.MethodsFrom 2019 to 2020, the probability proportionate to size sampling method was deployed to representatively invite approximately 20,000 adults (18 or older) throughout HCMC to free screening and linkage to care for HCV.FindingsIn HCMC, the weighted prevalence of anti-HCV was 1·3% (95% CI, 1·1%-1·6%). Individuals born from 1945 to 1964 had the anti-HCV prevalence of 3·6% (95% CI, 3·0%-4·2%) and represented 40·4% of all HCV cases. There were wide variations in anti-HCV prevalence in HCMC, including variations between districts, risk factors, and socioeconomic statuses. A baseline HCV continuum of care for the city demonstrated that only 28·5% (85/298, 95%CI 23·4-33·7%) of persons with anti-HCV (+) were aware of their HCV status, with 77.6% (66/85, 95%CI 68·8-86·5%) diagnosing HCV incidentally, 82·7% (62/75, 95%CI 74·1-91·2%) initiating anti-HCV therapy, and 53.6% (30/56, 95%CI 40·5-66·6%) achieving HCV cures.InterpretationThere remains a considerable disease burden of HCV in HCMC of which a significant proportion was in the age group born between 1945 to 1964. Additionally, there were significant gaps in HCV awareness, screening, and access to care in the community in Viet Nam. Thus, future interventions must have pragmatic targets, be tailored to the local needs, and emphasise screening.FundingThis work was supported by investigator-sponsored research grants from Gilead Sciences Inc. (Grant No: IN-US-987-5382); Roche Diagnostic International Ltd. (Grant No. SUB-000196); and in-kind donations from Abbott Diagnostic Viet Nam; Hepatitis B Foundation; Medic Medical Center, Viet Nam; Johns Hopkins University School of Medicine's Center of Excellence for Liver Disease in Viet Nam; and the Board of Directors, Viet Nam Viral Hepatitis Alliance (V-VHA).

Published
2022

6. Racial and Ethnic Disparities in Liver Transplantation for Alcohol-associated Liver Diseases in the United States

Author

Cotter, Thomas G., Mitchell, Mack C., Patel, Mausam J., Anouti, Ahmad, Lieber, Sarah R., Rich, Nicole E., Arab, Juan Pablo, Díaz, Luis Antonio, Louissaint, Jeremy, Kerr, Thomas, Mufti, Arjmand R., Hanish, Steven I., Vagefi, Parsia A., Patel, Madhukar S., VanWagner, Lisa B., Lee, William M., O’Leary, Jacqueline G., and Singal, Amit G.

Published
2024
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10. Racial and Ethnic Disparities in Liver Transplantation for Alcohol-associated Liver Diseases in the United States

Author

Cotter, Thomas G., Mitchell, Mack C., Patel, Mausam J., Anouti, Ahmad, Lieber, Sarah R., Rich, Nicole E., Arab, Juan Pablo, Díaz, Luis Antonio, Louissaint, Jeremy, Kerr, Thomas, Mufti, Arjmand R., Hanish, Steven I., Vagefi, Parsia A., Patel, Madhukar S., VanWagner, Lisa B., Lee, William M., O’Leary, Jacqueline G., and Singal, Amit G.

Published
2023
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12. REPLY: The exact predictive value of HBcrAg and HBV RNA in serological status and disease activity in CHB

Author

Ghany, Marc G., primary, King, Wendy C., additional, Hinerman, Amanda S., additional, Lok, Anna S.F., additional, Lisker-Melman, Mauricio, additional, Chung, Raymond T., additional, Terrault, Norah, additional, Janssen, Harry L.A., additional, Khalili, Mandana, additional, Lee, William M., additional, Lau, Daryl T.Y., additional, Cloherty, Gavin A., additional, and Sterling, Richard K., additional

Published
2024
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13. LBO-005 Intervention with oral LPCN 1148 improves sarcopenia and hepatic encephalopathy (HE) in patients with cirrhosis: a 52-week phase 2 randomized clinical trial

Author

Bruno, Benjamin, primary, Weavil, Josh, additional, Ogle, Jonathan, additional, Chidambaram, Nachaippan, additional, Carey, Elizabeth, additional, Danford, Christopher, additional, Fricker, Zachary, additional, Galati, Joseph, additional, Lee, William M., additional, Mantry, Parvez, additional, Shetty, Kirti, additional, DelConte, Anthony, additional, Patel, Mahesh, additional, Sanyal, Arun J., additional, and Lai, Jennifer, additional

Published
2024
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14. TOP-352 Serum proteomics can help identify new prognostic biomarkers in adults with acute liver failure

Author

Remih, Katharina, primary, Hufnagel, Franziska, additional, Karl, Anna, additional, Durkalski-Mauldin, Valerie, additional, Lee, William M., additional, Su, Zemin, additional, Rule, Jody, additional, Tomanova, Petra, additional, Krieg, Laura, additional, Karkossa, Isabel, additional, Schubert, Kristin, additional, von Bergen, Martin, additional, Luckhardt, Sonja, additional, Ziegler, Nicole, additional, Kannt, Aimo, additional, Fontana, Robert, additional, and Strnad, Pavel, additional

Published
2024
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15. WED-164 Interim safety results of the ongoing international phase I/II GATEWAY gene therapy trial with VTX-801 conducted in adult patients with Wilson disease

Author

Sandahl, Thomas Damgaard, primary, Lee, William M., additional, Ala, Aftab, additional, Gonzalez-Peralta, Regino P., additional, Medici, Valentina, additional, Askari, Fred, additional, Rudnick, Sean, additional, Lauer, Ulrich, additional, Schmidt, Hartmut, additional, Valero, Sonia, additional, Gonzalez, Gloria, additional, Combal, Jean Philippe, additional, D'Antiga, Lorenzo, additional, Benichou, Bernard, additional, and Schilsky, Michael, additional

Published
2024
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16. High Neutrophil–Lymphocyte Ratio and Delta Neutrophil–Lymphocyte Ratio Are Associated with Increased Mortality in Patients with Hepatocellular Cancer

Author

Rich, Nicole E., Parvathaneni, Aarthi, Sen, Ahana, Odewole, Mobolaji, Arroyo, Ana, Mufti, Arjmand R., Kerr, Thomas A., Grant, Lafaine, Tujios, Shannan R., Mayo, Marlyn J., Lee, William M., Yang, Ju Dong, Yokoo, Takeshi, Gopal, Purva, Hoshida, Yujin, Zhu, Hao, Yopp, Adam C., Marrero, Jorge A., and Singal, Amit G.

Published
2022
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17. Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B

Author

Di Bisceglie, Adrian M, King, Wendy C, Lisker‐Melman, Mauricio, Khalili, Mandana, Belle, Steven H, Feld, Jordan J, Ghany, Marc G, Janssen, Harry LA, Lau, Daryl, Lee, William M, Ling, Simon C, Cooper, Stewart, Rosenthal, Philip, Schwarz, Kathleen B, Sterling, Richard K, Teckman, Jeffrey H, Terrault, Norah, and Network, the Hepatitis B Research

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Chronic Liver Disease and Cirrhosis, Hepatitis, Hepatitis - B, Genetics, Clinical Research, Digestive Diseases, Infectious Diseases, Liver Disease, 4.2 Evaluation of markers and technologies, 2.1 Biological and endogenous factors, Detection, screening and diagnosis, Aetiology, Infection, Good Health and Well Being, Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, DNA, Viral, Female, Genotype, Hepatitis B e Antigens, Hepatitis B virus, Hepatitis B, Chronic, Humans, Infant, Male, Middle Aged, Population Groups, Public Health Surveillance, Seroepidemiologic Studies, Viral Load, Young Adult, e antigen, hepatitis B, natural history, Hepatitis B Research Network, Microbiology, Medical Microbiology, Gastroenterology & Hepatology, Clinical sciences, Medical microbiology
Abstract

Hepatitis B e antigen (HBeAg) is an important serological marker of hepatitis B virus (HBV) infection and is associated with higher levels of viraemia, increased risk of infectivity to others and increased risk of hepatocellular carcinoma. We analysed HBeAg status in a large cohort of adults and children enrolled in Cohort Studies of the Hepatitis B Research Network, long-term natural history studies of chronic HBV infection. A cross-sectional analysis examined factors associated with HBeAg positivity, including demographic and virologic data, across the age spectrum. Among 2241 enrolled participants who met criteria for this analysis, 825 (37%) were seropositive for HBeAg. The prevalence of HBeAg was lower in those with older age, ranging from 85% among those up to 10 years of age to only 12% among those older than 50 years. In addition to age, both race and HBV genotype were independently associated with HBeAg positivity. There was a significant interaction between age and race; the prevalence of HBeAg was significantly higher among Asians > 10-30 years old vs Whites or Blacks who were >10 to 30 years old and those infected with HBV genotype C. Conversely, the presence of the basal core promoter and precore variants was associated with significantly lower prevalence of HBeAg, even when adjusted for age, race and genotype. These data will provide a better understanding of factors associated with seropositivity for HBeAg and may lead to better strategies for preventing HBV infection and broader indications for antiviral therapy.

Published
2019

20. Clinical characteristics and HLA associations of azithromycin‐induced liver injury.

Author

Conlon, Caroline, Li, Yi‐Ju, Ahmad, Jawad, Barnhart, Huiman, Fontana, Robert J., Ghabril, Marwan, Hayashi, Paul H., Kleiner, David E., Lee, William M., Navarro, Victor, Odin, Joseph A., Phillips, Elizabeth J., Stolz, Andrew, Vuppalanchi, Raj, and Halegoua‐DeMarzio, Dina

Subjects
CHILD patients, LIVER injuries, LIVER failure, LIVER transplantation, GENE frequency
Abstract

Summary: Background: Azithromycin (AZ) is a widely used antibiotic. The aim of this study was to characterise the clinical features, outcomes, and HLA association in patients with drug‐induced liver injury (DILI) due to AZ. Methods: The clinical characteristics of individuals with definite, highly likely, or probable AZ‐DILI enrolled in the US Drug‐Induced Liver Injury Network (DILIN) were reviewed. HLA typing was performed using an Illumina MiSeq platform. The allele frequency (AF) of AZ‐DILI cases was compared to population controls, other DILI cases, and other antibiotic‐associated DILI cases. Results: Thirty cases (4 definite, 14 highly likely, 12 probable) of AZ‐DILI were enrolled between 2004 and 2022 with a median age of 46 years, 83% white, and 60% female. Median duration of AZ treatment was 5 days. Latency was 18.5 days. 73% were jaundiced at presentation. The injury pattern was hepatocellular in 60%, cholestatic in 27%, and mixed in 3%. Ten cases (33%) were severe or fatal; 90% of these were hepatocellular. Two patients required liver transplantation. One patient with chronic liver disease died of hepatic failure. Chronic liver injury developed in 17%, of which 80% had hepatocellular injury at onset. HLA‐DQA1*03:01 was significantly more common in AZ‐DILI versus population controls and amoxicillin‐clavulanate DILI cases (AF: 0.29 vs. 0.11, p = 0.001 and 0.002, respectively). Conclusion: Azithromycin therapy can lead to rapid onset of severe hepatic morbidity and mortality in adult and paediatric populations. Hepatocellular injury and younger age were associated with worse outcomes. HLA‐DQA1*03:01 was significantly more common in AZ cases compared to controls. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Macrophage activation markers are associated with infection and mortality in patients with acute liver failure.

Author

Cavazza, Anna, Triantafyllou, Evangelos, Savoldelli, Roberto, Mujib, Salma, Jerome, Ellen, Trovato, Francesca M., Artru, Florent, Sheth, Roosey, Huang, Xiao Hong, Ma, Yun, Dazzi, Francesco, Pirani, Tasneem, Antoniades, Charalambos G., Lee, William M., McPhail, Mark J., and Karvellas, Constantine J.

Subjects
LIVER failure, MACROPHAGE activation, ENZYME-linked immunosorbent assay, MORTALITY, CD14 antigen
Abstract

Background and Aims: Acute liver failure is a multisystem disorder with a high mortality and frequent need for emergency liver transplantation. Following massive innate immune system activation, soluble markers of macrophage activation are released during liver damage and their association with disease severity and prognosis requires exploration. Methods: Patients ALF from the United States Acute Liver Failure Study Group (USALFSG, n = 224) and King's College Hospital (n = 40) together with healthy controls (HC, n = 50) were recruited. Serum from early (Days 1–3) and late (>Day 3) time points were analysed for MAMs by enzyme‐linked immunosorbent assay correlated to markers of illness severity and 21‐day spontaneous survival. Surface expression phenotyping was performed via Flow Cytometry on CD14+ monocytes. Results: All MAMs serum concentrations were significantly higher in ALF compared to controls (p <.0001). sCD206 concentration was higher in early and late stages of the disease in patients with bacteraemia (p =.002) and infection in general (p =.006). In MELD‐adjusted multivariate modelling, sCD206 and sCD163 were independently associated with mortality. CD14+ monocyte expression of CD206 (p <.001) was higher in patients with ALF compared with controls and correlated with SOFA score (p =.018). sCD206 was independently validated as a predictor of infection in an external cohort. Conclusions: sCD206 is increased in serum of ALF patients with infections and poor outcome and is upregulated on CD14+ monocytes. Later measurements of sCD163 and sCD206 during the evolution of ALF have potential as mechanistic predictors of mortality. sCD206 should be explored as a biomarker of sepsis and mortality in ALF. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Acetaminophen-induced Acute Liver Failure Is More Common and More Severe in Women

Author

Rubin, Jessica B, Hameed, Bilal, Gottfried, Michelle, Lee, William M, Sarkar, Monika, and Group, Acute Liver Failure Study

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Rare Diseases, Clinical Research, Chronic Liver Disease and Cirrhosis, Liver Disease, Digestive Diseases, Oral and gastrointestinal, Good Health and Well Being, Acetaminophen, Adult, Aged, Analgesics, Non-Narcotic, Antipyretics, Female, Humans, Incidence, Liver Failure, Acute, Male, Middle Aged, North America, Sex Factors, Survival Analysis, APAP, ALFSG, Tylenol, Paracetamol, Gender, Narcotics, Acute Liver Failure Study Group, Gastroenterology & Hepatology, Clinical sciences
Abstract

Background & aimsAcetaminophen overdose is the leading cause of acute liver injury (ALI) and acute liver failure (ALF) in the developed world. Sex differences in acetaminophen-induced hepatotoxicity have not been described.MethodsWe collected data from the Acute Liver Failure Study Group cohort, a national registry of 32 academic medical centers in North America of adults with ALI or ALF, including 1162 patients with acetaminophen-induced ALI (n = 250) or acetaminophen-induced ALF (n = 912) from January 2000 through September 2016. We analyzed data on patient presentation, disease course, demographics, medical and psychiatric history, medication use, substance use, and details of acetaminophen ingestion. Sex differences in continuous and categorical variables were evaluated by Wilcoxon rank-sum and χ2 analysis or the Fisher exact test. Our primary aim was to evaluate sex differences in the presentation and clinical course of acetaminophen-induced acute liver injury or liver failure, and our secondary goal was to compare overall and transplant-free survival between sexes.ResultsMost patients with acetaminophen-induced ALI (68%) or ALF (76%) were women. Higher proportions of women than men had psychiatric disease (60% of women vs 48% of men, P < .01) and had co-ingestion with sedating agents (70% of women vs 52% of men, P

Published
2018

24. Clinical and Neurologic Outcomes in Acetaminophen-Induced Acute Liver Failure: A 21-Year Multicenter Cohort Study

Author

Lee, William M., Larson, Anne M., Liou, Iris, Fix, Oren, Schilsky, Michael, McCashland, Timothy, Eileen Hay, J., Murray, Natalie, Shaikh, A. Obaid S., Blei, Andres, Ganger, Daniel, Zaman, Atif, Han, Steven H.B., Robert Fontana, McGuire, Brendan, Chung, Raymond T., Smith, Alastair, Brown, Robert, Crippin, Jeffrey, Harrison, Edwin, Reuben, Adrian, Munoz, Santiago, Reddy, Rajender, Todd Stravitz, R., Rossaro, Lorenzo, Satyanarayana, Raj, Hassanein, Tarek, Karvellas, Constantine J., Olson, Jodi, Subramanian, Ram, Hanje, James, Hameed, Bilal, MacDonald, Andrew J., Speiser, Jaime L., Ganger, Daniel R., Nilles, Kathleen M., and Orandi, Babak J.

Published
2021
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25. Racial and ethnic disparities in alcohol-associated liver disease in the United States: A systematic review and meta-analysis

Author

Anouti, Ahmad, primary, Seif El Dahan, Karim, additional, Rich, Nicole E., additional, Louissaint, Jeremy, additional, Lee, William M., additional, Lieber, Sarah R., additional, Arab, Juan Pablo, additional, Zhang, Bill Y., additional, Patel, Mausam J., additional, Thimphittaya, Chanattha, additional, Díaz, Luis Antonio, additional, Gregory, Dyanna L., additional, Kozlitina, Julia, additional, VanWagner, Lisa B., additional, King, Andrea C., additional, Mitchell, Mack C., additional, Singal, Amit G., additional, and Cotter, Thomas G., additional

Published
2024
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31. Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection

Author

Lau, Daryl T-Y., Chung, Raymond T., Roberts, Lewis R., Hassan, Mohamed A., Lisker-Melman, Mauricio, Wong, David K., Juan, Joshua, Yim, Colina, Patel, Keyur, Murakami, Carol S., Do, Son, Han, Steven-Huy B., Tran, Tram T., Khalili, Mandana, Cooper, Stewart L., Fontana, Robert J., Tsai, Naoky, Younoszai, Barak, Muir, Andrew, Evon, Donna, Darling, Jama M., Carithers, Robert C., Shuhart, Margaret, Kowdley, Kris V., Wang, Chia C., Sterling, Richard K., Ghany, Marc G., Liang, T. Jake, Hoofnagle, Jay H., Doo, Edward, Chang, Kyong-Mi, Park, Jang-June, Wahed, Abdus, Cloonan, Yona, Kleiner, David, Brahmania, Mayur, Lombardero, Manuel, Hansen, Bettina E., Terrault, Norah A., Lok, Anna S., Perrillo, Robert P., Belle, Steven H., Di Bisceglie, Adrian M., Feld, Jordan J., Lee, William M., Fried, Michael W., and Janssen, Harry L.A.

Published
2019
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33. Characteristics of Adults in the Hepatitis B Research Network in North America Reflect Their Country of Origin and Hepatitis B Virus Genotype

Author

Ghany, Marc G, Perrillo, Robert, Li, Ruosha, Belle, Steven H, Janssen, Harry LA, Terrault, Norah A, Shuhart, Margaret C, Lau, Daryl T-Y, Kim, W Ray, Fried, Michael W, Sterling, Richard K, Di Bisceglie, Adrian M, Han, Steven-Huy B, Ganova-Raeva, Lilia Milkova, Chang, Kyong-Mi, Lok, Anna Suk-Fong, Network, Hepatitis B Research, Chung, Raymond T, Roberts, Lewis R, Smith, Coleman I, Lisker-Melman, Mauricio, Wong, David K, Juan, Joshua, Feld, Jordan, Yim, Colina, Heathcoate, Jenny, Lee, William M, Do, Son, Tran, Tram T, Khalili, Mandana, Cooper, Stewart L, Fontana, Robert J, Tsai, Naoky, Patel, Keyur, Evon, Donna, Carithers, Robert C, Kowdley, Kris V, Wang, Chia C, Liang, T Jake, Park, Jang-June, Wahed, Abdus, Kleiner, David, Afdhal, Nezam, Javaid, Asad, Niu, Jianghe, Han, Johanna, Nasser, Imad, Stahler, Alisha C, Stadheim, Linda, Hassan, Mohamed, King, Debra L, Nagy, Rosemary A, La, Danie, Liu, Lucie, Minshall, Stacey, Bass, Sheila, French, Samuel, Peacock, Velma, Ungermann, Ashley, Ayala, Claudia, Olson, Emma, Lau, Ivy, Podolskaya, Veronika, DeVole, Nata, McKenna, Barbara, Oberhelman, Kelly, Kaza, Sravanthi, Rodd, Cassandra, Huddleston, Leslie, Poerzgen, Peter, Darling, Jama M, Barritt, A Sidney, Marsh, Tiffany, Metheny, Vikki, Cardona, Danielle, Luketic, Velimir A, Smith, Paula G, Hofmann, Charlotte, Mathisen, Terri, Strom, Susan, Mooney, Jody, Cardona-Gonzalez, Lupita, Fryzek, Nancy, Rivera, Elenita, Morris, Nevitt, Haynes-Williams, Vanessa, Valiga, Mary E, Torrey, Keith, Levine, Danielle, Keith, James, Betts, Michael, Montaner, Luis J, Teo, Chong-Gee, Khudyakov, Yury, Punkova, Lili T, Cloonan, Yona, Danielson, Michelle, Haller, Tamara, Johnson, Geoffrey, and Kelley, Stephanie

Subjects
Liver Disease, Infectious Diseases, Hepatitis, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Hepatitis - B, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Adolescent, Adult, Aged, Aged, 80 and over, Canada, Emigrants and Immigrants, Female, Genotype, Hepatitis B virus, Hepatitis B, Chronic, Humans, Male, Middle Aged, United States, Young Adult, HBeAg, Chronic Hepatitis B Virus Infection, USA, ALT, Hepatitis B Research Network, Clinical Sciences, Gastroenterology & Hepatology
Abstract

Background & aimsChronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma worldwide; populations that migrate to the United States and Canada might be affected disproportionately. The Hepatitis B Research Network (HBRN) is a cooperative network of investigators from the United States and Canada, created to facilitate clinical, therapeutic, and translational research in adults and children with hepatitis B. We describe the structure of the network and baseline characteristics of adults with hepatitis B enrolled in the network.MethodsThe HBRN collected data on the clinical characteristics of 1625 adults with chronic HBV infection who are not receiving antiviral therapy from 21 clinical centers in North America.ResultsHalf of the subjects in the HBRN are men, and the median age is 42 years; 72% are Asian, 15% are black, and 11% are white; with 82% born outside of North America. The most common HBV genotype was B (39%); 74% of subjects were negative for the hepatitis B e antigen. The median serum level of HBV DNA when the study began was 3.6 log10 IU/mL; 68% of male subjects and 67% of female subjects had alanine aminotransferase levels higher than the normal range.ConclusionsThe HBRN cohort is used to address important clinical and therapeutic questions for North Americans infected with chronic HBV and to guide health policies on HBV prevention and management in North America.

Published
2015

37. Biliary atresia and liver transplantation in the United States: A contemporary analysis

Author

Anouti, Ahmad, primary, Patel, Madhukar S., additional, VanWagner, Lisa B., additional, Lee, William M., additional, Fung, John J., additional, Cholankeril, George, additional, Hwang, Christine S., additional, Mufti, Arjmand R., additional, Tujios, Shannan, additional, Kerr, Thomas, additional, Rich, Nicole E., additional, Louissaint, Jeremy, additional, Desai, Dev M., additional, Vagefi, Parsia A., additional, Hanish, Steven, additional, Shah, Jigesh, additional, Singal, Amit G., additional, and Cotter, Thomas G., additional

Published
2023
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41. Increasing practice and acceptable outcomes of high-MELD living donor liver transplantation in the USA

Author

Anouti, Ahmad, primary, Patel, Madhukar S., additional, VanWagner, Lisa B., additional, Lee, William M., additional, Asrani, Sumeet K., additional, Mufti, Arjmand R., additional, Rich, Nicole E., additional, Vagefi, Parsia A., additional, Shah, Jigesh A., additional, Kerr, Thomas A., additional, Pedersen, Mark, additional, Hanish, Steven, additional, Singal, Amit G., additional, and Cotter, Thomas G., additional

Published
2023
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42. Serum proteomics in American adults with acute liver failure

Author

Remih, Katharina, primary, Hufnagel, Franziska, additional, Durkalski-Mauldin, Valerie, additional, Lee, William M., additional, Su, Zemin, additional, Rule, Jody, additional, Krieg, Laura, additional, Karkossa, Isabel, additional, Schubert, Kristin, additional, von Bergen, Martin, additional, Fontana, Robert, additional, and Strnad, Pavel, additional

Published
2023
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43. Soluble and monocyte surface CD206 is a promising indicator of sepsis in patients with acute liver failure

Author

Cavazza, Anna, primary, Triantafyllou, Evangelos, additional, Savoldelli, Roberto, additional, Mujib, Salma, additional, Jerome, Ellen, additional, Trovato, Francesca, additional, Artru, Florent, additional, Sheth, Roosey, additional, Abdalla, Rima, additional, Huang, Xiaohong, additional, Ma, Yun, additional, Dazzi, Francesco, additional, Antoniades, Charalambos Gustav, additional, Lee, William M., additional, McPhail, Mark J W, additional, and Karvellas, Constantine, additional

Published
2023
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46. Association of Variants of Arginine Vasopressin and Arginine Vasopressin Receptor 1A With Severe Acetaminophen Liver Injury

Author

Reuben, Adrian, Fontana, Robert J., Davern, Timothy, McGuire, Brendan, Stravitz, R. Todd, Durkalski, Valerie, Liou, Iris, Fix, Oren, Schilsky, Michael, Ganger, Daniel, Chung, Raymond T., Koch, David, Reddy, K. Rajender, Rossaro, Lorenzo, Randesi, Matthew, Levran, Orna, Correa da Rosa, Joel, Hankins, Julia, Rule, Jody, Kreek, Mary Jeanne, and Lee, William M.

Published
2017
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48. HBV-Associated Acute Liver Failure After Immunosuppression and Risk of Death

Author

Lee, W.M., Larson, Anne M., Liou, Iris, Fix, Oren, Schilsky, Michael, McCashland, Timothy, Hay, J. Eileen, Murray, Natalie, Shaikh, A. Obaid S., Blei, Andres, Ganger, Daniel, Zaman, Atif, Han, Steven H.B., Fontana, Robert, McGuire, Brendan, Chung, Raymond T., Smith, Alastair, Brown, Robert, Crippin, Jeffrey, Harrison, Edwin, Reuben, Adrian, Munoz, Santiago, Reddy, Rajender, Stravitz, R. Todd, Rossaro, Lorenzo, Satyanarayana, Raj, Hassanein, Tarek, Karvellas, Constantine J., Olson, Jodi, Subramanian, Ram, Hanje, James, Cardoso, Filipe S., Gottfried, Michelle, Reddy, K. Rajender, Hanje, A. James, and Lee, William M.

Published
2017
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