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6. Routine Stress Testing After PCI in Patients With and Without Acute Coronary Syndrome: A Secondary Analysis of the POST-PCI Randomized Clinical Trial.

Author

Lee, Jinho, Kang, Do-Yoon, Kim, Hoyun, Choi, Yeonwoo, Jo, Sangyong, Ahn, Jung-Min, Kim, Seonok, Yoon, Yong-Hoon, Hur, Seung-Ho, Lee, Cheol Hyun, Kim, Won-Jang, Kang, Se Hun, Park, Chul Soo, Lee, Bong-Ki, Suh, Jung-Won, Choi, Jae Woong, Kim, Kee-Sik, Lee, Su Nam, Park, Seung-Jung, and Park, Duk-Woo

Published
2024
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7. Pragmatic trial comparing routine versus no routine functional testing in high-risk patients who underwent percutaneous coronary intervention: Rationale and design of POST-PCI trial

Author

Yoon, Yong-Hoon, Ahn, Jung-Min, Kang, Do-Yoon, Park, Hanbit, Cho, Sang-Cheol, Lee, Pil Hyung, Hur, Seung-Ho, Kim, Won-Jang, Park, Chul Soo, Lee, Bong-Ki, Suh, Jung-Won, Yoon, Jung Han, Choi, Jae Woong, Kim, Ki-Sik, Choi, Si Wan, Lee, Su Nam, Park, Seung-Jung, and Park, Duk-Woo

Published
2020
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10. Comparative Analysis of High-Intensity versus Low-to-Moderate Intensity Statin Therapy in Patients Undergoing Rotational Atherectomy for Calcified Coronary Artery Disease

Author

Choi, Sang-Suk, primary, Jung, Jin, additional, Her, Sung-Ho, additional, Kim, Kyunyeon, additional, Kim, Youngmin, additional, Lee, Kyusup, additional, Yoo, Ki-Dong, additional, Moon, Keon-Woong, additional, Moon, Donggyu, additional, Lee, Su-Nam, additional, Jang, Won-Young, additional, Choi, Ik-Jun, additional, Lee, Jae-Hwan, additional, Lee, Jang-Hoon, additional, Lee, Sang-Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong-Ho, additional, and Lee, Hyun-Jong, additional

Published
2023
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11. Routine stress testing in diabetic patients after percutaneous coronary intervention: the POST-PCI trial

Author

Kim, Hoyun, primary, Kang, Do-Yoon, additional, Lee, Jinho, additional, Choi, Yeonwoo, additional, Ahn, Jung-Min, additional, Kim, Seonok, additional, Yoon, Yong-Hoon, additional, Hur, Seung-Ho, additional, Lee, Cheol Hyun, additional, Kim, Won-Jang, additional, Kang, Se Hun, additional, Park, Chul Soo, additional, Lee, Bong-Ki, additional, Suh, Jung-Won, additional, Choi, Jae Woong, additional, Kim, Kee-Sik, additional, Lee, Su Nam, additional, Park, Seung-Jung, additional, and Park, Duk-Woo, additional

Published
2023
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13. Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy

Author

Jung, Jin, primary, Seo, Yeonjoo, additional, Her, Sung-Ho, additional, Lee, Jae-Hwan, additional, Lee, Kyusup, additional, Yoo, Ki-Dong, additional, Moon, Keon-Woong, additional, Moon, Donggyu, additional, Lee, Su-Nam, additional, Jang, Won-Young, additional, Choi, Ik-Jun, additional, Lee, Jang-Hoon, additional, Lee, Sang-Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong-Ho, additional, and Lee, Hyun-Jong, additional

Published
2023
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14. Routine stress testing in diabetic patients after percutaneous coronary intervention: the POST-PCI trial.

Author

Kim, Hoyun, Kang, Do-Yoon, Lee, Jinho, Choi, Yeonwoo, Ahn, Jung-Min, Kim, Seonok, Yoon, Yong-Hoon, Hur, Seung-Ho, Lee, Cheol Hyun, Kim, Won-Jang, Kang, Se Hun, Park, Chul Soo, Lee, Bong-Ki, Suh, Jung-Won, Choi, Jae Woong, Kim, Kee-Sik, Lee, Su Nam, Park, Seung-Jung, and Park, Duk-Woo

Subjects
PERCUTANEOUS coronary intervention, PEOPLE with diabetes, CORONARY angiography, ANGINA pectoris, MYOCARDIAL infarction
Abstract

Background and Aims The optimal follow-up surveillance strategy for high-risk diabetic patients with had undergone percutaneous coronary intervention (PCI) remains unknown. Methods The POST-PCI (Pragmatic Trial Comparing Symptom-Oriented versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention) study was a randomized trial comparing a follow-up strategy of routine functional testing at 1 year vs. standard care alone after high-risk PCI. Randomization was stratified according to diabetes status. The primary outcome was a composite of death from any cause, myocardial infarction, or hospitalization for unstable angina at 2 years. Results Among 1706 randomized patients, participants with diabetes (n = 660, 38.7%) had more frequent comorbidities and a higher prevalence of complex anatomical or procedural characteristics than those without diabetes (n = 1046, 61.3%). Patients with diabetes had a 52% greater risk of primary composite events [hazard ratio (HR) 1.52; 95% confidence interval (CI) 1.02–2.27; P =.039]. The 2-year incidences of the primary composite outcome were similar between strategies of routine functional testing or standard care alone in diabetic patients (7.1% vs. 7.5%; HR 0.94; 95% CI 0.53–1.66; P =.82) and non-diabetic patients (4.6% vs. 5.1%; HR 0.89; 95% CI 0.51–1.55; P =.68) (interaction term for diabetes: P =.91). The incidences of invasive coronary angiography and repeat revascularization after 1 year were higher in the routine functional-testing group than the standard-care group irrespective of diabetes status. Conclusions Despite being at higher risk for adverse clinical events, patients with diabetes who had undergone high-risk PCI did not derive incremental benefit from routine surveillance stress testing compared with standard care alone during follow-up. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Associations of polyneuropathy with risk of all‐cause and cardiovascular mortality, cardiovascular disease events stratified by diabetes status.

Author

Kim, Kyuho, Lee, Su‐Nam, Ahn, Yu‐Bae, Ko, Seung‐Hyun, and Yun, Jae‐Seung

Subjects
*CARDIOVASCULAR diseases, *POLYNEUROPATHIES, *CARDIOVASCULAR fitness, *MORTALITY, *PROPORTIONAL hazards models, *TYPE 2 diabetes, *CARDIOVASCULAR diseases risk factors, CARDIOVASCULAR disease related mortality
Abstract

Aims/Introduction: We investigated the association of polyneuropathy (PN) with all‐cause and cardiovascular (CV) mortality and with cardiovascular disease (CVD) events stratified by diabetes status. Materials and Methods: This prospective cohort study used the UK Biobank. Polyneuropathy was defined based on nurse‐led interviews or ICD codes for polyneuropathy. Cox proportional hazards models were used to investigate the association of polyneuropathy with clinical outcomes. Results: A total of 459,127 participants were included in the analysis. Polyneuropathy was significantly associated with all‐cause and cardiovascular mortality, and with CVD events even after adjusting for CVD risk factors across all diabetes statuses. Metabolic parameters HbA1c, waist circumference, BMI and the inflammatory parameter C‐reactive protein showed significant mediation effects for the association between polyneuropathy and CVD. Adherence to a favorable lifestyle was associated with a lower risk of all‐cause and cardiovascular mortality regardless of polyneuropathy status. Conclusions: Polyneuropathy was associated with all‐cause and cardiovascular mortality, and with CVD events in subjects with diabetes or prediabetes, even those having normal glucose tolerance. This study suggests the importance of polyneuropathy as a risk factor for death and highlights the necessity of early diagnosis and lifestyle intervention for those with type 2 diabetes and polyneuropathy. [ABSTRACT FROM AUTHOR]

Published
2023
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17. Long-Term Clinical Impact of Patients with Multi-Vessel Non-Obstructive Coronary Artery Disease.

Author

Jung, Jin, Lee, Su-Nam, Her, Sung-Ho, Yoo, Ki-Dong, Moon, Keon-Woong, Moon, Donggyu, and Jang, Won-Young

Subjects
*CORONARY artery disease, *MYOCARDIAL infarction, *CORONARY angiography, *STROKE
Abstract

Background: Non-obstructive coronary artery disease (CAD) is a disease commonly diagnosed in patients undergoing coronary angiography. However, little is known regarding the long-term clinical impact of multi-vessel non-obstructive CAD. Therefore, the object of this study was to investigate the long-term clinical impact of multi-vessel non-obstructive CAD. Method: A total of 2083 patients without revascularization history and obstructive CAD were enrolled between January 2010 and December 2015. They were classified into four groups according to number of vessels involved in non-obstructive CAD (25% ≤ luminal stenosis < 70%): zero, one, two, or three diseased vessels (DVs). We monitored the patients for 5 years. The primary outcome was major cardiovascular and cerebrovascular events (MACCEs), defined as a composite of cardiac death, stroke, and myocardial infarction (MI). Result: The occurrence of MACCEs increased as the number of non-obstructive DVs increased, and was especially high in patients with three DVs. After adjustment, patients with three DVs still showed significantly poorer clinical outcomes of MACCEs, stroke, and MI compared those with zero DVs. Conclusion: Multi-vessel non-obstructive CAD, especially in patients with non-obstructive three DVs, is strongly associated with poor long-term clinical outcomes. This finding suggests that more intensive treatment may be required in this subset of patients. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Prognostic Impact of Periprocedural Myocardial Infarction in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy

Author

Jung, Jin, primary, Her, Sung-Ho, primary, Lee, Kyusup, primary, Yoo, Ki-Dong, primary, Moon, Keon-Woong, primary, Moon, Donggyu, primary, Lee, Su Nam, primary, Jang, Won Young, primary, Choi, Ik Jun, primary, Lee, Jae-Hwan, primary, Lee, Jang Hoon, primary, Lee, Sang Rok, primary, Lee, Seung-Whan, primary, Yun, Kyeong Ho, primary, and Lee, Hyun-Jong, primary

Published
2023
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21. Triple Antiplatelet Therapy with Cilostazol and Favorable Early Clinical Outcomes after Acute Myocardial Infarction Compared to Dual Antiplatelet Therapy with Standard or Potent P2Y12 Inhibitors

Author

Byun, Sungwook, primary, Lee, Su Nam, additional, Lim, Sungmin, additional, Choo, Eun Ho, additional, Choi, Ik Jun, additional, Kim, Chan Joon, additional, Moon, Donggyu, additional, Park, Mahn-Won, additional, Park, Chul Soo, additional, Ahn, Youngkeun, additional, Jeong, Myung-Ho, additional, and Chang, Kiyuk, additional

Published
2022
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22. Clinical Outcomes of Biodegradable versus Durable Polymer Drug Eluting Stents in Rotational Atherectomy: Results from ROCK Registry

Author

Kim, Kyung An, primary, Her, Sung-Ho, additional, Lee, Kyusup, additional, Choi, Ik Jun, additional, Lee, Jae-Hwan, additional, Lee, Jang Hoon, additional, Lee, Sang Rok, additional, Lee, Pil Hyung, additional, Lee, Seung-Whan, additional, Yoo, Ki Dong, additional, Lee, Su Nam, additional, Jang, Won Young, additional, Moon, Donggyu, additional, Moon, Keon-Woong, additional, Yun, Kyeong Ho, additional, and Lee, Hyun-Jong, additional

Published
2022
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23. Impacts of gender and lifestyle on the association between depressive symptoms and cardiovascular disease risk in the UK Biobank.

Author

Lee, Su Nam, Yun, Jae-Seung, Ko, Seung-Hyun, Ahn, Yu-Bae, Yoo, Ki-Dong, Her, Sung-Ho, Moon, Donggyu, Jung, Sang-Hyuk, Won, Hong-Hee, and Kim, Dokyoon

Subjects
*MENTAL depression, *SYMPTOMS, *HEALTH behavior, *CARDIOVASCULAR diseases, *SLEEP duration, *CARDIOVASCULAR diseases risk factors, *ATRIAL flutter, *SMOKING cessation, *FEMALES
Abstract

We investigated the effects of gender and lifestyle on the association between frequency of depressive symptoms and CVD risk. The UK Biobank is a national prospective cohort study that recruited 502,505 participants aged 40–69 years between 2006 and 2010. Participants without CVD were classified as having low, moderate, high, or very high frequency of depressive symptoms according to the number of days they felt depressed in a 2-week period. UKBB data include self-reported questionnaires covering lifestyle behaviors such as smoking, physical activity, eating habits, and sleep duration. The primary outcomes included incident CVD including coronary artery disease, ischemic stroke, hemorrhagic stroke, peripheral artery disease, atrial fibrillation/flutter, and heart failure. Cox proportional hazard models were used to evaluate the effects of gender and lifestyle on the association of frequency of depressive symptoms and CVD risk. During a median follow-up of 8.9 years, 27,394 (6.3%) developed CVD. The frequency of depressive symptoms increased the risk of CVD according to low, moderate, high, and very high frequency of depressive symptoms (P for trend < 0.001). The adjusted CVD risk was 1.38-fold higher for participants with very high frequency of depressive symptoms compared to those with low frequency of depressive symptoms (HR 1.38, 95% CI 1.24–1.53, P < 0.001). The correlation between frequency of depressive symptoms and CVD risk was more remarkable in females than in males. In participants with high or very high frequency of depressive symptoms, the individual lifestyle factors of no current smoking, non-obesity, non-abdominal obesity, regular physical activity, and appropriate sleep respectively was associated with lower CVD risk by 46% (HR 0.54, 95% CI 0.48–0.60, P < 0.001), 36% (HR 0.64, 95% CI 0.58–0.70, P < 0.001), 31% (HR 0.69, 95% CI 0.62–0.76, P < 0.001), 25% (HR 0.75, 95% CI 0.68–0.83, P < 0.001), and 22% (HR 0.78, 95% CI 0.71–0.86, P < 0.001). In this large prospective cohort study, a higher frequency of depressive symptoms at baseline was significantly associated with increased risk of CVD in the middle-aged population, and this relationship was prominent in women. In the middle-aged population with depressive symptoms, engaging in a healthier lifestyle could prevent CVD risk. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Routine Functional Testing or Standard Care in High-Risk Patients after PCI

Author

Park, Duk-Woo, primary, Kang, Do-Yoon, additional, Ahn, Jung-Min, additional, Yun, Sung-Cheol, additional, Yoon, Yong-Hoon, additional, Hur, Seung-Ho, additional, Lee, Cheol Hyun, additional, Kim, Won-Jang, additional, Kang, Se Hun, additional, Park, Chul Soo, additional, Lee, Bong-Ki, additional, Suh, Jung-Won, additional, Yoon, Jung Han, additional, Choi, Jae Woong, additional, Kim, Kee-Sik, additional, Choi, Si Wan, additional, Lee, Su Nam, additional, and Park, Seung-Jung, additional

Published
2022
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25. Impact of Low Baseline Low‐Density Lipoprotein Cholesterol on Long‐Term Postdischarge Cardiovascular Outcomes in Patients With Acute Myocardial Infarction

Author

Cho, Kyung Hoon, primary, Kim, Min Chul, additional, Choo, Eun Ho, additional, Choi, Ik Jun, additional, Lee, Su Nam, additional, Park, Mahn‐Won, additional, Park, Chul Soo, additional, Kim, Hee‐Yeol, additional, Kim, Chan Joon, additional, Sim, Doo Sun, additional, Kim, Ju Han, additional, Hong, Young Joon, additional, Jeong, Myung Ho, additional, Chang, Kiyuk, additional, and Ahn, Youngkeun, additional

Published
2022
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26. Impact of diabetes mellitus on periprocedural and 18-month clinical outcomes in Korean patients requiring rotational atherectomy: results from the ROCK Registry

Author

Lee, Su Nam, primary, Moon, Donggyu, additional, Her, Sung-Ho, additional, Jang, Won Young, additional, Moon, Keon-Woong, additional, Yoo, Ki-Dong, additional, Lee, Kyusup, additional, Lee, Jae Hwan, additional, Lee, Jang Hoon, additional, Lee, Sang Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong Ho, additional, Lee, Hyun-Jong, additional, and Choi, Ik Jun, additional

Published
2022
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28. Impact of Diabetes Duration on Clinical Outcome in Patients Receiving Rotational Atherectomy in Calcified Lesions in Korea—Results from ROCK Registry

Author

Jung, Jin, primary, Her, Sung-Ho, additional, Lee, Kyusup, additional, Jung, Ji-Hoon, additional, Yoo, Ki-Dong, additional, Moon, Keon-Woong, additional, Moon, Donggyu, additional, Lee, Su-Nam, additional, Jang, Won-Young, additional, Choi, Ik-Jun, additional, Lee, Jae-Hwan, additional, Lee, Jang-Hoon, additional, Lee, Sang-Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong-Ho, additional, and Lee, Hyun-Jong, additional

Published
2022
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30. Optimal reperfusion strategy in acute high-risk pulmonary embolism requiring extracorporeal membrane oxygenation support: a systematic review and meta-analysis

Author

Chopard, Romain, primary, Nielsen, Peter, additional, Ius, Fabio, additional, Cebotari, Serghei, additional, Ecarnot, Fiona, additional, Pilichowski, Hugo, additional, Schmidt, Matthieu, additional, Kjaergaard, Benedict, additional, Sousa-Casasnovas, Iago, additional, Ghoreishi, Mehrdad, additional, Narayan, Rajeev L., additional, Lee, Su Nam, additional, Piazza, Gregory, additional, and Meneveau, Nicolas, additional

Published
2022
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31. Impact of Diabetes duration on Clinical outcome in Patients receiving Rotational Atherectomy from ROCK Registry : a multicenter, retrospective study.

Author

JUNG, JIN, primary, Her, Sung-Ho, additional, Lee, Kyusup, additional, Jung, Ji-Hoon, additional, You, Ki-Dong, additional, Moon, Keon-Woong, additional, Moon, Donggyu, additional, Lee, Su Nam, additional, Jang, Won Young, additional, Choi, Ik Jun, additional, Lee, Jae Hwan, additional, Lee, Jang Hoon, additional, Lee, Sang Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong Ho, additional, and Lee, Hyun-Jong, additional

Published
2022
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33. Temporal Trends of Major Bleeding and Its Prediction by the Academic Research Consortium-High Bleeding Risk Criteria in Acute Myocardial Infarction

Author

Byun, Sungwook, primary, Choo, Eun Ho, additional, Oh, Gyu-Chul, additional, Lim, Sungmin, additional, Choi, Ik Jun, additional, Lee, Kwan Yong, additional, Lee, Su Nam, additional, Hwang, Byung-Hee, additional, Kim, Chan Joon, additional, Park, Mahn-Won, additional, Park, Chul Soo, additional, Kim, Hee-Yeol, additional, Yoo, Ki-Dong, additional, Jeon, Doo Soo, additional, Youn, Ho Joong, additional, Chung, Wook Sung, additional, Kim, Min Chul, additional, Jeong, Myung Ho, additional, Yim, Hyeon-Woo, additional, Ahn, Youngkeun, additional, and Chang, Kiyuk, additional

Published
2022
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34. Impact of Diabetes Duration on Clinical Outcome in Patients Receiving Rotational Atherectomy from ROCK Registry

Author

Jung, Jin, primary, Her, Sung-Ho, additional, Lee, Kyusup, additional, Yoo, Ki-Dong, additional, Moon, Keon-Woong, additional, Moon, Donggyu, additional, Lee, Su Nam, additional, Jang, Won Young, additional, Choi, Ik Jun, additional, Lee, Jae Hwan, additional, Lee, Jang Hoon, additional, Lee, Sang Rok, additional, Lee, Seung-Whan, additional, Yun, Kyeong Ho, additional, and Lee, Hyun-Jong, additional

Published
2022
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37. Risks of Recurrent Cardiovascular Events and Mortality in 1-Year Survivors of Acute Myocardial Infarction Implanted with Newer-Generation Drug-Eluting Stents

Author

Lim, Sungmin, primary, Choo, Eun Ho, additional, Choi, Ik Jun, additional, Lee, Kwan Yong, additional, Lee, Su Nam, additional, Hwang, Byung-Hee, additional, Kim, Chan Joon, additional, Park, Mahn-Won, additional, Lee, Jong-Min, additional, Park, Chul Soo, additional, Kim, Hee-Yeol, additional, Yoo, Ki-Dong, additional, Jeon, Doo Soo, additional, Youn, Ho Joong, additional, Chung, Wook Sung, additional, Kim, Min Chul, additional, Jeong, Myung Ho, additional, Yim, Hyeon Woo, additional, Ahn, Youngkeun, additional, and Chang, Kiyuk, additional

Published
2021
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38. Effect of smoking on clinical outcomes in patients receiving rotational atherectomy in calcified coronary lesions: from the ROCK Registry, South Korea

Author

Jang, Won Young, primary, Lee, Su Nam, additional, Her, Sung-Ho, additional, Moon, Donggyu, additional, Moon, Keon-Woong, additional, Yoo, Ki-Dong, additional, Lee, Kyusup, additional, Choi, Ik Jun, additional, Lee, Jae Hwan, additional, Lee, Jang Hoon, additional, Lee, Sang Rok, additional, Lee, Seung-Wan, additional, Yun, Kyeong Ho, additional, and Lee, Hyun-Jong, additional

Published
2021
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40. Impact of diabetes mellitus on periprocedural and 18-month clinical outcomes in Korean patients requiring rotational atherectomy: results from the ROCK Registry.

Author

Su Nam Lee, Donggyu Moon, Sung-Ho Her, Won Young Jang, Keon-Woong Moon, Ki-Dong Yoo, Kyusup Lee, Jae Hwan Lee, Jang Hoon Lee, Sang Rok Lee, Seung-Whan Lee, Kyeong Ho Yun, Hyun-Jong Lee, Ik Jun Choi, Lee, Su Nam, Moon, Donggyu, Her, Sung-Ho, Jang, Won Young, Moon, Keon-Woong, and Yoo, Ki-Dong

Published
2022
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41. Associations between Body Mass Index and Clinical Outcomes in Acute Myocardial Infarction Supported with Extracorporeal Membrane Oxygenation

Author

Lee, Su Nam, Moon, Donggyu, Jo, Min Seop, and Yoo, Ki-Dong

Subjects
Original Article
Abstract

BACKGROUND: Previous studies have reported a "body mass index (BMI) paradox" with acute myocardial infarction (AMI), whereby overweight patients are associated with lower mortality. The aim of this study was to evaluate the impact of BMI on survival of patients with AMI supported with extracorporeal membrane oxygenation (ECMO). METHODS: Between May 2009 and July 2018, 60 patients with AMI who underwent ECMO were enrolled from a single center. Receiver operating characteristic curve analysis was used to determine a cutoff for BMI. Patients were divided into two groups: normal weight (18.5 ≤ BMI < 23 kg/m(2), n = 27) and overweight (BMI ≥ 23 kg/m(2), n = 33). The composite outcome was all-cause mortality at 30 days. RESULTS: The overweight group was significantly younger than the normal weight group, and there was a statistically significant difference between the two groups in electrocardiography before ECMO. Ventricular tachycardia or fibrillation occurred in 11 (33.3%) overweight patients, and asystole or pulseless electrical activity occurred in 10 (37%) normal weight patients. More of the normal weight group had successful percutaneous coronary interventions than the overweight group. The overweight group was significantly associated with lower mortality [hazard ratio (HR): 0.491; 95% confidence interval (CI) = 0.267-0.903] at 30 days, which persisted after multivariate adjustments (HR: 0.442; 95% CI = 0.210-0.928). To determine predictive factors for mortality, multivariate logistic analysis revealed that overweight [odds ratio (OR) 0.102; 95% CI (0.018-0.564); p = 0.009] and ECMO under cardiopulmonary resuscitation [OR 19.009; 95% CI (2.139-168.956); p = 0.008] were significantly associated with all-cause mortality at 30 days. CONCLUSIONS: Overweight was associated with lower mortality in AMI patients supported with ECMO.

Published
2020

42. Effects of Smoking on Long-Term Clinical Outcomes and Lung Cancer in Patients with Acute Myocardial Infarction

Author

Lee, Su Nam, primary, Choi, Ik Jun, additional, Lim, Sungmin, additional, Choo, Eun Ho, additional, Hwang, Byung-Hee, additional, Kim, Chan Joon, additional, Park, Mahn-Won, additional, Lee, Jong-Min, additional, Park, Chul Soo, additional, Kim, Hee Yeol, additional, Yoo, Ki-Dong, additional, Jeon, Doo Soo, additional, Youn, Ho Joong, additional, Chung, Wook-Sung, additional, Kim, Min Chul, additional, Jeong, Myung Ho, additional, Ahn, Youngkeun, additional, and Chang, Kiyuk, additional

Published
2021
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45. A Case of a 50-Year-Old Woman with Typical Fabry Disease Who Showed Serial Electrocardiographic and Echocardiographic Changes over a 17-Year Period

Author

Lee, Su Nam, Kim, Gee-Hee, and Yoo, Ki-Dong

Subjects
Article Subject
Abstract

Fabry disease (FD) is a progressive, X-linked lysosomal storage disorder caused by a deficiency of α-galactosidase A activity. Affected individuals accumulate globotriaosylceramide and glycosphingolipids in the lysosomes and cytoplasm of cells throughout the body, leading to major organ failure and premature death. Cardiac involvement includes left ventricular hypertrophy, arrhythmia, endothelial dysfunction at vascular wall, and cardiomyopathy. The diagnosis of FD can be difficult and there is often a long lag time between symptoms and diagnosis. Here, we present a case of a 50-year-old woman with typical Fabry disease who showed serial electrocardiographic and echocardiographic changes over 17 years prior to diagnosis with Fabry disease.

Published
2019
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48. IMPACT OF FAMILY HISTORY OF PREMATURE CORONARY ARTERY DISEASE ON MORTALITY IN PATIENTS WITH SUSPECTED CORONARY ARTERY DISEASE UNDERGOING CORONARY CT ANGIOGRAPHY.

Author

Lee, Su Nam, Han, Donghee, Cho, Sung Woo, Gransar, Heidi, Dey, Damini, Slomka, Piotr, Hayes, Sean W., Friedman, John D., Thomson, Louise, and Berman, Daniel S.

Subjects
*CORONARY artery disease, *CARDIOGRAPHIC tomography, *CORONARY angiography, *FAMILY history (Medicine), *MORTALITY
Published
2024
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