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Purpose: The paper is a comprehensive review of the literature on manufacturing technologies thick-layer coatings on various substrates and manufacturing gradient materials using powders of metals, their alloys and ceramics. Design/methodology/approach: Extensive literature studies on manufacturing technologies thick-layer coatings on various substrates and manufacturing gradient materials using powders of metals, their alloys and ceramics have been carried out. The paper is illustrated with examples of various structure images obtained as part of research of engineering materials made by authors with powders. By using knowledge engineering methods, development perspectives of individual technologies were indicated. Findings: The manufacturing technologies thick-layer coatings on various substrates and manufacturing gradient materials using powders of metals, their alloys and ceramics as the advanced digital production (ADP) technologies are proves the highest possible potential and relatively good attractiveness, as well as their fully exploited attractiveness or substantial development opportunities in this respect. Originality/value: According to augmented holistic Industry 4.0 model, many materials processing technologies and among them manufacturing technologies thick-layer coatings on various substrates and manufacturing gradient materials using powders of metals, their alloys and ceramics are becoming very important among product manufacturing technologies. They are an essential part of powder engineering.

Purpose: The paper is a literature review indicating the importance of powder engineering in the modern stage of Industry 4.0 development. 47 technologies for the manufacturing and use the powders of metal and their alloys and ceramic in the manufacturing of products are indicated. All those technologies were compared in terms of their potential and attractiveness, pointing to their development trends. The focus was solely on powder production methods. Other technologies will be discussed in other papers in the powder engineering cycle. Design/methodology/approach: The authors' considerations are based on an extensive literature study and the results of the authors' previous studies and empirical work. In order to compare the analyzed technologies, the methodology of knowledge engineering are used, including the own method of contextual matrices for comparative analysis of a large set of technologies by presenting them on a dendrological matrix. Findings: The most interesting intellectual achievements contained in the paper include presentations of the authors' original concepts regarding the augmentation of the Industry 4.0 model. Material processing technologies occupy an important place in it, among them powder engineering technologies, both conventional and additive. The most attractive and promising development technologies in powder engineering are identified. Originality/value: The originality of the paper is associated with the novelty of the approach to analysing powder engineering, an indication of its importance for the development of the Industry 4.0 idea, where progress does not depend only on the development of IT technologies. It is also not true that from among technologies only additive technologies play a key role. Using avant-garde analyses in the field of knowledge engineering, the most avant-garde technologies of powder engineering are pointed out.

This paper is a literature review with additional virtual analyses of the authors’ own experimental research results. Knowledge from various areas was synergistically combined, appropriately for concurrent engineering, presenting several possible methodological approaches used in research, optimizing the selection of engineering materials and the conditions of their application with particular application in endodontics. Particular attention was paid to the theoretical aspects of filling material strengths, weaknesses, opportunities, and threats SWOT analysis. Attention was paid to the original concepts of Sustainable Dentistry Development in conjunction with Dentistry 4.0, which includes endodontics as an important element. The dentists’ actions, among others, in conservative dentistry, along with endodontics, requires close cooperation with engineers and the enginering sciences. Methods of root canal preparation were described, together with selected tools, including those made of nitinol. Principles concerning the process of cleaning and shaping the pulp complex are presented. The importance of obturation methods, including the Thermo-Hydraulic-Condensation THC technique, and the selection of filling materials with the necessary sealants for the success of endodontic treatment are discussed. The experimental studies were carried out in vitro on human teeth removed for medical reasons, except for caries, for which two groups of 16 teeth were separated. After the root canal was prepared, it was filled with studs and pellets of a filling material based on polyester materials, which has gained the common trade name of resilon or, less frequently, RealSeal (SybronEndo) with an epiphany sealant. The teeth for the first group were obturated by cold lateral condensation. In the second case the obturation was performed using the Thermo-Hydraulic-Condensation technique using System B and Obtura III. The experimental leakage testing was done using a scanning electron microscope SEM and a light stereoscopic microscope LSM, as typical research tools used in materialography. The research results, in a confrontation with the data taken from the literature studies, do not indicate the domination of resilon in endodontics.

Purpose: Among the technologies that play a crucial role in the current stage of development of Industry 4.0 conventional powder engineering technologies are of great importance. Based on a comprehensive literature review, conventional technologies using the powders of metals, their alloys and ceramics are described. Development perspectives of the most widespread among them were indicated. Design/methodology/approach: Extensive literature studies on conventional powder engineering technologies have been carried out. By using knowledge engineering methods, development perspectives of individual technologies were indicated. Findings: In addition to the presentation of conventional sintering technological methods, sintering mechanisms in solid-state and liquid phase sintering which accounts for 90% of the commercial value of sintered products are presented. Originality/value: According to augmented holistic Industry 4.0 model, many materials processing technologies and among them conventional powder engineering technologies play a key role in current industry development. For this reason, these technologies have been characterized in detail on the basis of available literature sources.

Purpose: The purpose of this study is to present the author's method of planning the procedure of immediate implant-prosthetic restoration in place of a tooth qualified for removal by performing a surgical template and implant-prosthetic restoration based on data obtained in the CBCT test and intraoral scanning 3D model. Design/methodology/approach: The method of planning the implant surgery through the design and manufacture of surgical templates and implant prostheses performed before the start of medical procedures was described on the basis of actual clinical data from patients with anterior segment teeth qualified for extraction for reasons of complications after endodontic treatment. The placement of the implant was planned using virtual reality, where the bone model and the virtual soft tissue model were combined, which made it possible to perform a surgical template and prosthetic implant restoration. For the manufacturing, 3D printing as stereolithography SLA and selective laser sintering SLS for the surgical template manufacturing and CNC milling in the case of the prosthetic implant were used for restoration. Findings: The method allows planning the implant position based on two connected bone and soft tissue models and allows to design and manufacture a surgical guide. In this way, it becomes possible to place implants in the patient's bone during surgery procedure in the planned position and to install the prosthetic implant restoration in the form of an individual abutment and a PMMA crown during the same procedure in the surgical part. Practical implications: Thanks to the method of computer-aided design/manufacturing CAD/CAM production of surgical templates and prosthetic restoration based only on digital models and the planned position of the implant, it is possible to carry out the procedure of immediate tooth extraction and replacement with permanent prosthetic restoration. The whole process is based on the CBCT test performed at the beginning. The presented method allows shortening the procedure time by four times and the rehabilitation time by 3-6 months when performing the procedure in a minimally invasive manner. Originality/value: This article presents the original design and production method of surgical guides. It allows for precise planning of the implant position and transfer of this data to the patient's mouth during the procedure, enabling permanent prosthetic restoration before starting medical procedures.

From time immemorial to the present day, health has been considered to be of the highest value [...]

This paper concerns the assessment of the current state of dentistry in the world and the prospects of its sustainable development. A traditional Chinese censer was adopted as the pattern, with a strong and stable support on three legs. The dominant diseases of the oral cavity are caries and periodontal diseases, with the inevitable consequence of toothlessness. From the caries 3.5–5 billion people suffer. Moreover, each of these diseases has a wide influence on the development of systemic complications. The territorial range of these diseases and their significant differentiation in severity in different countries and their impact on disability-adjusted life years index are presented (DALY). Edentulousness has a significant impact on the oral health-related quality of life (OHRQoL). The etiology of these diseases is presented, as well as the preventive and therapeutic strategies undertaken as a result of modifying the Deming circle through the fives’ rules idea. The state of development of Dentistry 4.0 is an element of the current stage of the industrial revolution Industry 4.0 and the great achievements of modern dental engineering. Dental treatment examples from the authors’ own clinical practice are given. The systemic safety of a huge number of dentists in the world is discussed, in place of the passive strategy of using more and more advanced personal protective equipment (PPE), introducing our own strategy for the active prevention of the spread of pathogenic microorganisms, including SARS-CoV-2. The ethical aspects of dentists’ activity towards their own patients and the ethical obligations of the dentist community towards society are discussed in detail. This paper is a polemic arguing against the view presented by a group of eminent specialists in the middle of last year in The Lancet. It is impossible to disagree with these views when it comes to waiting for egalitarianism in dental care, increasing the scope of prevention and eliminating discrimination in this area on the basis of scarcity and poverty. The views on the discrimination of dentistry in relation to other branches of medicine are far more debatable. Therefore, relevant world statistics for other branches of medicine are presented. The authors of this paper do not agree with the thesis that interventional dental treatment can be replaced with properly implemented prophylaxis. The final remarks, therefore, present a discussion of the prospects for the development of dentistry based on three pillars, analogous to the traditional Chinese censer obtaining a stable balance thanks to its three legs. The Dentistry Sustainable Development (DSD) > 2020 model, consisting of Global Dental Prevention (GDP), Advanced Interventionist Dentistry 4.0 (AID 4.0), and Dentistry Safety System (DSS), is presented.

The general goals of advanced digitized production in the Industry 4.0 stage of the industrial revolution were presented along with the extended holistic model of Industry 4.0, introduced by the authors, indicating the importance of material design and the selection of appropriate manufacturing technology. The effect of the global lockdown caused by the SARS-CoV-2 virus transmission pandemic was a drastic decrease in production, resulting in a significant decrease in the gross domestic product GDP in all countries, and gigantic problems in health care, including dentistry. Dentists belong to the highest risk group because the doctor works in the patient&rsquo, s respiratory tract. This paper presents a breakthrough authors solution, implemented by the active SPEC strategy, and aims to eliminate clinical aerosol at the source by negative pressure aspirating bioaerosol at the patient&rsquo, s mouth line. The comparative benchmarking analysis and its results show that only the proprietary solution with a set of devices eliminates the threat at the source, while the remaining known methods do not meet the expectations. The details of this solution are described. Photopolymer materials and additive Digital Light Printing (DLP) technology were used.

The paper is a comprehensive but compact review of the literature on the state of illnesses of the human stomatognathic system, related consequences in the form of dental deficiencies, and the resulting need for prosthetic treatment. Types of prosthetic restorations, including implants, as well as new classes of implantable devices called implant-scaffolds with a porous part integrated with a solid core, as well as biological engineering materials with the use of living cells, have been characterized. A review of works on current trends in the technical development of dental prosthetics aiding, called Dentistry 4.0, analogous to the concept of the highest stage of Industry 4.0 of the industrial revolution, has been presented. Authors’ own augmented holistic model of Industry 4.0 has been developed and presented. The studies on the significance of cone-beam computed tomography (CBCT) in planning prosthetic treatment, as well as in the design and manufacture of prosthetic restorations, have been described. The presented and fully digital approach is a radical turnaround in both clinical procedures and the technologies of implant preparation using computer-aided design and manufacturing methods (CAD/CAM) and additive manufacturing (AM) technologies, including selective laser sintering (SLS). The authors’ research illustrates the practical application of the Dentistry 4.0 approach for several types of prosthetic restorations. The development process of the modern approach is being observed all over the world. The use of the principles of the augmented holistic model of Industry 4.0 in advanced dental engineering indicates a change in the traditional relationship between a dentist and a dental engineer. The overall conclusion demonstrates that it is inevitable and extremely beneficial to implement the idea of Dentistry 4.0 following the assumptions of the authors’ own, holistic Industry 4.0 model.

Purpose: The article concerns the development of completely new groups of composite materials that can be used to produce functional replacements for damaged bones or teeth. Design/methodology/approach: A selective laser sintering was used to produce the reinforcement of those materials from titanium and its Ti6Al4V alloy in the form of skeletons with pores with adjustable geometric features. The matrix of those materials is either air or crystallised from the liquid AlSi12 or AlSi7Mg0.3 alloys condition after prior vacuum infiltration or human osteoblast cells from the hFOB 1.19 (Human ATCC - CRL - 11372) culture line. Findings: The porous material may be used for the non-biodegradable scaffold. After implantation into the body in the form of an implant-scaffold one, it allows the natural cells of the patient to grow into the pores of the implant, and it fuses with the bone or the appropriate tissue over time. The essential part of the implant-scaffold is the porous part inseparably connected with the core of solid materials. Into pores can grow living cells. Research limitations/implications: Biological-engineering composite materials in which natural cells were cultured in the pores in the laboratory next are combined as an artificial material with the natural cells of the patient in his/her body. Practical implications: The hybrid technologies of the all group of those materials were obtained and optimised. Numerous structure research was carried out using the most modern research methods of contemporary materials engineering, and mechanical tests and biological research involving the cultivation of natural cells were realised. Originality/value: The results of the research indicate the accuracy of the idea of implementing a new group of biological-engineering materials and the wide possibilities of their application in regenerative medicine.

Purpose: The publication aims to find the relationship between the proliferation of surface layers of living cells and the deposition of thin atomic layers deposition ALD coatings on the pores internal surfaces of porous skeletons of medical and dental implant-scaffolds manufactured with the selective laser deposition SLS additive technology using titanium and Ti6Al4V alloy. Design/methodology/approach: The extensive review of the literature presents the state-of-the-art in the field of regenerative medicine and tissue engineering. General ageing of societies, increasing the incidence of oncological diseases and some transport and sports accidents, and also the spread of tooth decay and tooth cavities in many regions of the world has taken place nowadays. Those reasons involve resection of many tissues and organs and the need to replace cavities, among others bones and teeth through implantation, more and more often hybridized with tissue engineering methods. Findings: The results of investigations of the structure and properties of skeleton microporous materials produced from titanium and Ti6Al4V alloy powders by the method of selective laser sintering have been presented. Particularly valuable are the original and previously unpublished results of structural research using high-resolution transmission electron microscope HRTEM. Particular attention has been paid to the issues of surface engineering, in particular, the application of flat TiO2 and Al2O3 coatings applied inside micropores using the atomic layers deposition ALD method and hydroxyapatite applied the dip-coating sol-gel method, including advanced HRTEM research. The most important part of the work concerns the research of nesting and proliferation of live cells of osteoblasts the hFOB 1.19 (Human ATCC - CRL - 11372) culture line on the surface of micropores with surfaces covered with the mentioned layers. Research limitations/implications: The investigations reported in the paper fully confirmed the idea of the hybrid technology of producing microporous implants and implant-scaffolds to achieve original Authors’ biological-engineering materials. The surface engineering issues, including both flat-layered nonorganic coatings and interactions of those coverings with flat layers of living cells, play a crucial role. Originality/value: Materials commonly used in implantology and the most commonly used materials processing technologies in those applications have been described. Against that background, the original Authors' concept of implant-scaffolds and the application of microporous skeleton materials for this purpose have been presented.

A very extensive literature review presents the possibilities and needs of using, in endodontics, the alloys commonly known as nitinol. Nitinol, as the most modern group of engineering materials used to develop root canals, is equilibrium nickel and titanium alloys in terms of the elements’ atomic concentration, or very similar. The main audience of this paper is engineers, tool designers and manufacturers, PhD students, and students of materials and manufacturing engineering but this article can also certainly be used by dentists. The paper aims to present a full material science characterization of the structure and properties of nitinol alloys and to discuss all structural phenomena that determine the performance properties of these alloys, including those applied to manufacture the endodontic tools. The paper presents the selection of these alloys’ chemical composition and processing conditions and their importance in the endodontic treatment of teeth. The results of laboratory studies on the analysis of changes during the sterilization of endodontic instruments made of nitinol alloys are also included. The summary of all the literature analyses is an SWOT analysis of strengths, weaknesses, opportunities, and threats, and is a forecast of the development strategy of this material in a specific application such as endodontics.

This article is a literature review aimed at presenting the general state of knowledge in manufacturing engineering and materials engineering to develop engineering materials applied for endodontic treatment as filling materials. Particular attention was paid to theoretical analyses concerning the selection of methods for developing and obturating root canals and discussing the results of experimental studies available in the literature. These activities aimed to compare the importance of the most commonly used endodontic filling materials based on gutta-percha or polymeric polyester materials, commonly known as resilon, respectively. The motivation to take up this complex, multi-faceted topic in this paper is the extent of caries, periodontal disease, and other oral diseases in 3 to 5 billion people, often affecting toothlessness and contributing to an increase in the index of disability-adjusted life years (number). Endodontics is an important element of the authors’ concept of Dentistry Sustainable Development (DSD) > 2020. The principles of qualifying patients for endodontic treatment are discussed. The introduction of rotary tools, especially manufactured from Nitinol alloy, to develop root canals and the latest thermohydraulic and condensation techniques for obturation guarantee progress in endodontics. The “Digital Twins” methodology was used, rooted in the idea of Industry 4.0 and the resulting idea of Dentistry 4.0, as well as knowledge management methods, to perform experimental research in virtual space, concerning methods of developing and obturating the root canal and assessing the tightness of fillings. Microscopic visualization methods were also used. Significant factors determining the effectiveness of endodontic obturation are the selection of the filling material and the appropriate obturation method. The generalized dendrological matrix of endodontic filling materials considers the criteria of mechanical strength influencing the potential root fracture and the quality of root canal filling. The results of the SWOT point analysis (strengths and weaknesses, opportunities, threats) were also compared. For both filling materials, the weaknesses are much less than the strengths, while the threats are slightly less than the opportunities for the gutta-percha-based material, while for resilon the opportunities are much smaller than the threats. It requires the application of an appropriate development strategy, i.e., MAXI-MAXI in the case of a filling material based on gutta-percha and MAXI-MINI in the case of resilon. Therefore, the analysis of these experimental data does not indicate the real competitiveness of resilon for the gutta-percha-based material. This material deservedly maintains its strong position as the “Gold Standard of Endodontics”.

The paper is an extensive monographic review of the literature, and also uses the results of the authors’ own experimental research illustrating the noticed developmental tendencies of the filling material based on gutta-percha. The whole body of literature proves the correctness of the research thesis that this material is the best currently that can be used in endodontics. Caries is one of the most common global infectious diseases. Since the dawn of humankind, the consequence of the disease has been the loss of dentition over time through dental extractions. Both tooth caries and tooth loss cause numerous complications and systemic diseases, which have a serious impact on insurance systems and on the well-being, quality, and length of human life. Endodontic treatment, which has been developing since 1836, is an alternative to tooth extraction. Based on an extensive literature review, the methodology of qualifying patients for endodontic treatment was analyzed. The importance of selecting filling material and techniques for the development and obturation of the root canal during endodontic treatment was described. Particular attention was paid to the materials science aspects and the sequence of phase transformations and precipitation processes, as well as the need to ensure the stoichiometric chemical composition of Ni–Ti alloys, and the vacuum metallurgical processes and material processing technologies for the effects of shape memory and superelasticity, which determine the suitability of tools made of this alloy for endodontic purposes. The phenomena accompanying the sterilization of such tools, limiting the relatively small number of times of their use, play an important role. The methods of root canal preparation and obturation methods through cold side condensation and thermoplastic methods, including the most modern of them, the thermo-hydraulic condensation (THC) technique, were analyzed. An important element of the research hypothesis was to prove the assumption that to optimize the technology of development and obturation of root canals, tests of filling effectiveness are identified by the density and size of the gaps between the root canal wall, and the filling methods used and devices appropriate for material research, using mainly microscopy such as light stereoscopic (LSM) and scanning electron (SEM). The most beneficial preparations were obtained by making a longitudinal breakthrough of 48 natural human teeth, extracted for medical reasons, different from caries, with compliance with all ethical principles in this field. The teeth were prepared using various methods and filled with multiple obturation techniques, using a virtual selection of experimental variants. The breakthroughs were made in liquid nitrogen after a one-sided incision with a narrow gap created by a diamond disc using a materialographic cutter. The best effectiveness of the root canal filling was ensured by the technology of preparing the root canals with K3 rotary nitinol tools and filling the teeth with the THC thermoplastic method using the System B and Obtura III devices with studs and pellets of filling material based on gutta-percha after covering the root canal walls with a thin layer of AH Plus sealant. In this way, the research thesis was confirmed.

This paper is divided into seven main parts. Its purpose is to review the literature to demonstrate the importance of developing bioengineering and global production of biomaterials to care for the level of healthcare in the world. First, the general description of health as a universal human value and assumptions of a long and healthy life policy is presented. The ethical aspects of the mission of medical doctors and dentists were emphasized. The coronavirus, COVID-19, pandemic has had a significant impact on health issues, determining the world’s health situation. The scope of the diseases is given, and specific methods of their prevention are discussed. The next part focuses on bioengineering issues, mainly medical engineering and dental engineering, and the need for doctors to use technical solutions supporting medicine and dentistry, taking into account the current stage Industry 4.0 of the industrial revolution. The concept of Dentistry 4.0 was generally presented, and a general Bioengineering 4.0 approach was suggested. The basics of production management and the quality loop of the product life cycle were analyzed. The general classification of medical devices and biomedical materials necessary for their production was presented. The paper contains an analysis of the synthesis and characterization of biomedical materials supporting medicine and dentistry, emphasizing additive manufacturing methods. Numerous examples of clinical applications supported considerations regarding biomedical materials. The economic conditions for implementing various biomedical materials groups were supported by forecasts for developing global markets for biomaterials, regenerative medicine, and tissue engineering. In the seventh part, recapitulation and final remarks against the background of historical retrospection, it was emphasized that the technological processes of production and processing of biomedical materials and the systematic increase in their global production are a determinant of the implementation of a long and healthy policy.

This paper presents a comparison of the impact of milling technology in the computer numerically controlled (CNC) machining centre and selective laser sintering (SLS) and on the structure and properties of solid Ti6Al4V alloy. It has been shown that even small changes in technological conditions in the SLS manufacturing variant significantly affect changes from two to nearly two and a half times in tensile and bending strengths. Both the tensile and bending strength obtained in the most favourable manufacturing variant by the SLS method is over 25% higher than in the case of cast materials subsequently processed by milling. Plug-and-play SLS conditions provide about 60% of the possibilities. Structural, tribological and electrochemical tests were carried out. In vitro biological tests using osteoblasts confirm the good tendency for the proliferation of live cells on the substrate manufactured under the most favourable SLS conditions. The use of SLS additive technology for the manufacturing of dental implants and abutments made of Ti6Al4V alloy in combination with the digitisation of dental diagnostics and computer-aided design and manufacture of computer-aided design/manufacturing (CAD/CAM) following the idea of Dentistry 4.0 is the best choice of technology for manufacturing of prosthetic and implant devices used in dentistry.

The purpose of this paper is to compare the impact of selective laser-sintering (SLS) technology and computer numerical control (CNC) machining methods on the structure and properties of solid Co-Cr-W-Mo-Si alloys. Structural tests were carried out using x-ray structural analysis; energy-dispersive x-ray spectroscopy chemical composition analysis; metallographic investigations using stereoscopic, light, and scanning electron microscopes using computerized methods of quantitative metallography; and tests of tensile, bending, and compression strength. Individually designed microsamples were used, and the results were statistically processed. It was shown that if optimal conditions of SLS technology are used, it is possible to obtain a structure with a pore content of 0.1 % smaller than in the case of solid cast materials. This ensures better mechanical properties than cast materials. At the same time, it was pointed out that even minor technological errors associated with SLS technology caused a lowering of all strength properties associated with a significant increase in porosity by up to 10 %. Allowing small changes in technological conditions, including the width of the laser spot, the width of the laser beam, the allowance associated with the overlap of the laser beam, disturbances in the flow of inert gas, and uncontrolled changes in the laser power, can cause a significant reduction in strength. A plug and play approach is unacceptable. If even one layer with a thickness of 25 μm is produced in suboptimal conditions, the manufactured element cannot meet the assumed requirements. The use of SLS additive technology for the production of prosthetic components made of Co-Cr alloys is the best choice among the methods currently used in dentistry. The use of SLS technology together with the digitization of design and manufacturing processes is an important element in implementing the Dentistry 4.0 approach as part of the Industry 4.0 stage of the industrial revolution.

The aim of the research, the results of which are presented in the paper, is to fabricate, by Selective Laser Melting (SLM), a metallic scaffold with Ti6Al4V powder based on a virtual model corresponding to the actual loss of a patient’s craniofacial bone. A plaster cast was made for a patient with a palate recess, and the cast was then scanned with a 3D scanner to create a virtual 3D model of a palate recess, according to which a 3D model of a solid implant was created using specialist software. The virtual 3D solid implant model was converted into a 3D porous implant model after designing an individual shape of the unit cell conditioning the size and three-dimensional shape of the scaffold pores by multiplication of unit cells. The data concerning a virtual 3D porous implant model was transferred into a selective laser melting (SLM) device and a metallic scaffold was produced from Ti6Al4V powder with this machine, which was subjected to surface treatment by chemical etching. An object with certain initially adopted assumptions, i.e. shape and geometric dimensions, was finally achieved, which perfectly matches the patient bone recesses. The scaffold created was subjected to micro-and spectroscopic examinations.

The paper contains an extensive, richly illustrated literature study, theoretical studies, and practical work on current development trends of technical support for dental prosthetics. Dentistry 4.0 is the concept closely inspired by the highest stage Industry 4.0 of the industrial revolution. An augmented holistic Industry 4.0 model, which takes into account all other aspects, i.e., materials, processes, and technological machines and their development and informatics service, was developed and presented. The basis for consideration is the analysis of the disease in the human stomatognathic system and the possibility of prosthetic treatment in the event of a partial or total loss of natural dentition. In several centers, independent work on the popularization of individual implants manufactured using information obtained using conical beam computed tomography (CBCT) is carried out. The developed procedure requires one to make a three-dimensional bone base model based on the CBCT tomogram and its connection with the three-dimensional model of the dentition and soft tissues in the oral cavity, prepared on the basis of impression material, and most preferably a three-dimensional scan directly from the mouth. The presented and fully digitized approach is a radical turnaround in both clinical procedures and the method of technical implant preparation using Computer-Aided Design/Computer-Aided Manufacturing (CAD/CAM) methods and additive manufacturing technologies (AMT), including mainly Selective Laser Sintering (SLS) and stereolithography (SLA). The concept of hybrid multilayer biological-engineering composites is much more technologically advanced. The application of the principles of the augmented holistic Industry 4.0 model in modern dental engineering, according to the analysis, indicates a change in the traditional relationship between a dentist and dental engineer. The practical application of the Dentistry 4.0 approach is illustrated by projects regarding the manufacturing of a few dental restorations. The general conclusion indicates that the implementation of the ideas of Dentistry 4.0 following the assumptions of the augmented holistic model Industry 4.0 is inevitable and extremely beneficial.