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1. Ultrafast Transverse Modulation of Free Electrons by Interaction with Shaped Optical Fields

Author

Madan, I., Leccese, V., Mazur, A., Barantani, F., La Grange, T., Sapozhnik, A., Gargiulo, S., Rotunno, E., Olaya, J. -C., Kaminer, I., Grillo, V., de Abajo, F. J. García, Carbone, F., and Vanacore, G. M.

Subjects
Physics - Optics, Quantum Physics
Abstract

Spatio-temporal shaping of electron beams is a bold frontier in electron microscopy, enabling new routes toward spatial-resolution enhancement, selective probing, low-dose imaging and faster data acquisition. Over the last decade, shaping methods evolved from passive phase plates to low-speed electrostatic and magnetostatic displays. Recently, higher shaping speed and flexibility have become feasible by the advent of ultrafast electron microscopy, embodying a swift change of paradigm that relies on using light to control free electrons. Here, we experimentally demonstrate that arbitrary transverse modulation of electron beams is possible without the need for designing and fabricating complicated electron-optics elements or material nanostructures, but rather resorting to shaping light beams reflected from a planar thin film. We demonstrate arbitrary transverse modulation of electron wavepackets via inelastic interaction with a shaped ultrafast light field controlled by an external spatial light modulator (SLM). We illustrate this method by generating Hermite-Gaussian (HG) electron beams with HG10 and HG01 symmetry and discuss their possible use in enhancing the imaging contrast of microscopic features. Relative to current schemes, our approach adopting an external SLM dramatically widens the range of patterns that can be imprinted on the electron wave function and makes electron shaping a much easier task to perform., Comment: 21 pages, 5 figures

Published
2022

2. Sezione Quarta, Disciplina del rapporto individuale di lavoro - Titolo VII – Rapporti in azienda - Art. 3., Divieti. Commento

Author

Bavaro,V, Focareta,F, Lassandari,A, Scarpelli,F, Centamore,G, Martelloni,F, Nuzzo,V, McBritton,M, Recchia,GA, Di Noia,F, Cavallini,G, Sozzi,G, Varva,G, Moro,G, Giasanti,L, D’Onghia,M, Giaconi,M, Barbieri,M, Romani,F, Di Meo,R, Coppola,F, Laforgia,S, Marino,D, Leccese,V, Fenoglio,A, Campese,N, Nardulli,N, Del Vecchio,M, Veneto,M, Lategola,O, Piccinini,A, Covelli,R, Orlandini,G, Bavaro, V, Focareta, F, Lassandari, A, Scarpelli, F, Bavaro,V, Focareta,F, Lassandari,A, Scarpelli,F, Centamore,G, Martelloni,F, Nuzzo,V, McBritton,M, Recchia,GA, Di Noia,F, Cavallini,G, Sozzi,G, Varva,G, Moro,G, Giasanti,L, D’Onghia,M, Giaconi,M, Barbieri,M, Romani,F, Di Meo,R, Coppola,F, Laforgia,S, Marino,D, Leccese,V, Fenoglio,A, Campese,N, Nardulli,N, Del Vecchio,M, Veneto,M, Lategola,O, Piccinini,A, Covelli,R, Orlandini,G, Bavaro, V, Focareta, F, Lassandari, A, and Scarpelli, F

Abstract

Il contributo analizza la clausola di esclusiva dettata dalla disposizione in commento del CCNL Metalmeccanico, approfondendone le problematiche giuridiche applicative soprattutto alla luce della recente disciplina del tema contenuta nel d.lgs. 104/2022

Published
2023

3. Sezione Quarta, Disciplina del rapporto individuale di lavoro - Titolo I – Costituzione, tipologie, luogo della prestazione e modifiche del rapporto di lavoro, Art. 9. Appalti, Art. 10. Lavori pubblici di servizi. Commento

Author

Bavaro,V, Focareta,F, Lassandari,A, Scarpelli,F, Centamore,G, Martelloni,F, Nuzzo,V, McBritton,M, Recchia,GA, Di Noia,F, Cavallini,G, Sozzi,G, Varva,G, Moro,G, Giasanti,L, D’Onghia,M, Giaconi,M, Barbieri,M, Romani,F, Di Meo,R, Coppola,F, Laforgia,S, Marino,D, Leccese,V, Fenoglio,A, Campese,N, Nardulli,N, Del Vecchio,M, Veneto,M, Lategola,O, Piccinini,A, Covelli,R, Orlandini,G, Bavaro, V, Focareta, F, Lassandari, A, Scarpelli, F, Bavaro,V, Focareta,F, Lassandari,A, Scarpelli,F, Centamore,G, Martelloni,F, Nuzzo,V, McBritton,M, Recchia,GA, Di Noia,F, Cavallini,G, Sozzi,G, Varva,G, Moro,G, Giasanti,L, D’Onghia,M, Giaconi,M, Barbieri,M, Romani,F, Di Meo,R, Coppola,F, Laforgia,S, Marino,D, Leccese,V, Fenoglio,A, Campese,N, Nardulli,N, Del Vecchio,M, Veneto,M, Lategola,O, Piccinini,A, Covelli,R, Orlandini,G, Bavaro, V, Focareta, F, Lassandari, A, and Scarpelli, F

Abstract

Il contributo inquadra il ruolo del contratto collettivo nel sistema di disciplina degli aspetti lavoristici degli appalti privati e pubblici, ricostruendo il quadro giuridico generale di riferimento e analizzando le problematiche applicative della disciplina contrattuale oggetto del commento. Una specifica attenzione viene dedicata alla parte più innovativa del rinnovo 2021 del CCNL in commento, che ha introdotto una c.d. clausola sociale per i cambi di appalto nel settore degli appalti pubblici di servizi

Published
2023

4. Ultrafast Transverse Modulation of Free Electrons by Interaction with Shaped Optical Fields

Author

Madan, I, Leccese, V, Mazur, A, Barantani, F, Lagrange, T, Sapozhnik, A, Tengdin, P, Gargiulo, S, Rotunno, E, Olaya, J, Kaminer, I, Grillo, V, de Abajo, F, Carbone, F, Vanacore, G, Madan, Ivan, Leccese, Veronica, Mazur, Adam, Barantani, Francesco, LaGrange, Thomas, Sapozhnik, Alexey, Tengdin, Phoebe M, Gargiulo, Simone, Rotunno, Enzo, Olaya, Jean-Christophe, Kaminer, Ido, Grillo, Vincenzo, de Abajo, F Javier García, Carbone, Fabrizio, Vanacore, Giovanni Maria, Madan, I, Leccese, V, Mazur, A, Barantani, F, Lagrange, T, Sapozhnik, A, Tengdin, P, Gargiulo, S, Rotunno, E, Olaya, J, Kaminer, I, Grillo, V, de Abajo, F, Carbone, F, Vanacore, G, Madan, Ivan, Leccese, Veronica, Mazur, Adam, Barantani, Francesco, LaGrange, Thomas, Sapozhnik, Alexey, Tengdin, Phoebe M, Gargiulo, Simone, Rotunno, Enzo, Olaya, Jean-Christophe, Kaminer, Ido, Grillo, Vincenzo, de Abajo, F Javier García, Carbone, Fabrizio, and Vanacore, Giovanni Maria

Abstract

Spatiotemporal electron-beam shaping is a bold frontier of electron microscopy. Over the past decade, shaping methods evolved from static phase plates to low-speed electrostatic and magnetostatic displays. Recently, a swift change of paradigm utilizing light to control free electrons has emerged. Here, we experimentally demonstrate arbitrary transverse modulation of electron beams without complicated electron-optics elements or material nanostructures, but rather using shaped light beams. On-demand spatial modulation of electron wavepackets is obtained via inelastic interaction with transversely shaped ultrafast light fields controlled by an external spatial light modulator. We illustrate this method for the cases of Hermite-Gaussian and Laguerre-Gaussian modulation and discuss their use in enhancing microscope sensitivity. Our approach dramatically widens the range of patterns that can be imprinted on the electron profile and greatly facilitates tailored electron-beam shaping.

Published
2022

6. Parità di trattamento in materia di occupazione (D.Lgs. 9 luglio 2003, n. 216)

Author

Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, Zicchittu, P, Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, and Zicchittu, P

Published
2020

7. D.Lgs. 9 luglio 2003, n. 215 (parità di trattamento tra le persone)

Author

Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, Zicchittu, P, Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, and Zicchittu, P

Published
2020

8. L. 20 maggio 1970, n. 300 art. 1

Author

Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, Zicchittu, P, Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, and Zicchittu, P

Published
2020

9. Le tensioni del sistema di relazioni industriali e la riforma della rappresentanza

Author

Mariucci, L, Ferraro, G, Gragnoli, E, Lassandari, A, Scarponi, S, Leccese, V, Gottardi, G, Bellavista, A, Maresca, A, Zoppoli, A, Scarpelli, F, Bavaro, V, Carabelli, U, Camusso, S, Foccillo, A, Marignani, C, Vernola, J, SCARPELLI, FRANCO, Mariucci, L, Ferraro, G, Gragnoli, E, Lassandari, A, Scarponi, S, Leccese, V, Gottardi, G, Bellavista, A, Maresca, A, Zoppoli, A, Scarpelli, F, Bavaro, V, Carabelli, U, Camusso, S, Foccillo, A, Marignani, C, Vernola, J, and SCARPELLI, FRANCO

Abstract

Il contributo muove dai problemi di recente frammentazione del sistema di relazioni industriali italiano, per trarne la convinzione che sia oggi più motivato un intervento legislativo sulla contrattazione. Vengono però evidenziati alcuni snodi di difficile soluzione, affrontati in modo diverso dai progetti di legge elaborati da alcuni gruppi di studiosi e dalla principale organizzazione sindacale.

Published
2016

10. Appalti delle pubbliche amministrazioni e tutela dei lavoratori dipendenti da appaltatori e sub-appaltatori

Author

Mastrogiuseppe, P, Carabelli, U, Carinci, Mt, Viscomi, A, Spinelli, C, Trojsi, A, Nicosia, G, D'Onghia, M, Esposito, M, Roma, G, Leccese, V, Natullo, G, Imberti, L, Aimo, M, Bavaro, V, Calcaterra, L, Leone, G, Pinto, V, Voza, R, Chieco, P, Alvino, I, Marinelli, F, Di Stasi, A, Soloperto, R, Ludovico, G, Vimercati, A, Mc Britton, M, Carabelli, U, Carinci, MT, Mastrogiuseppe, P, Carinci, M, Viscomi, A, Spinelli, C, Trojsi, A, Nicosia, G, D'Onghia, M, Esposito, M, Roma, G, Leccese, V, Natullo, G, Imberti, L, Aimo, M, Bavaro, V, Calcaterra, L, Leone, G, Pinto, V, Voza, R, Chieco, P, Alvino, I, Marinelli, F, Di Stasi, A, Soloperto, R, Ludovico, G, Vimercati, A, and Mc Britton, M

Subjects
Appalto, subappalto, lavoro pubblico, tutela del lavoratore, Appalto, subappalto, lavoro pubblico, tutela del lavoratore, IUS/07 - DIRITTO DEL LAVORO
Published
2010

12. Appalti delle pubbliche amministrazioni e tutela dei lavoratori dipendenti da appaltatori e sub-appaltatori

Author

Carabelli, U, Carinci, MT, Mastrogiuseppe, P, Carinci, M, Viscomi, A, Spinelli, C, Trojsi, A, Nicosia, G, D'Onghia, M, Esposito, M, Roma, G, Leccese, V, Natullo, G, Imberti, L, Aimo, M, Bavaro, V, Calcaterra, L, Leone, G, Pinto, V, Voza, R, Chieco, P, Alvino, I, Marinelli, F, Di Stasi, A, Soloperto, R, Ludovico, G, Vimercati, A, Mc Britton, M, Mc Britton, M., ALVINO, ILARIO, Carabelli, U, Carinci, MT, Mastrogiuseppe, P, Carinci, M, Viscomi, A, Spinelli, C, Trojsi, A, Nicosia, G, D'Onghia, M, Esposito, M, Roma, G, Leccese, V, Natullo, G, Imberti, L, Aimo, M, Bavaro, V, Calcaterra, L, Leone, G, Pinto, V, Voza, R, Chieco, P, Alvino, I, Marinelli, F, Di Stasi, A, Soloperto, R, Ludovico, G, Vimercati, A, Mc Britton, M, Mc Britton, M., and ALVINO, ILARIO

Published
2010

15. Ultrafast Transverse Modulation of Free Electrons by Interaction with Shaped Optical Fields

Author

Ivan Madan, Veronica Leccese, Adam Mazur, Francesco Barantani, Thomas LaGrange, Alexey Sapozhnik, Phoebe M. Tengdin, Simone Gargiulo, Enzo Rotunno, Jean-Christophe Olaya, Ido Kaminer, Vincenzo Grillo, F. Javier García de Abajo, Fabrizio Carbone, Giovanni Maria Vanacore, Madan, I, Leccese, V, Mazur, A, Barantani, F, Lagrange, T, Sapozhnik, A, Tengdin, P, Gargiulo, S, Rotunno, E, Olaya, J, Kaminer, I, Grillo, V, de Abajo, F, Carbone, F, and Vanacore, G

Subjects
spectroscopy, PINEM, electron-beam shaping electron-photon interaction, diffraction, weak, phase plates, wave, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, electron-photon interaction, generation, microscopy, beams, electron-beam shaping, Electrical and Electronic Engineering, spatial light modulator, ultrafast transmission electron microscopy, Biotechnology
Abstract

Spatiotemporal electron-beam shaping is a bold frontier of electron microscopy. Over the past decade, shaping methods evolved from static phase plates to low-speed electrostatic and magnetostatic displays. Recently, a swift change of paradigm utilizing light to control free electrons has emerged. Here, we experimentally demonstrate arbitrary transverse modulation of electron beams without complicated electron-optics elements or material nanostructures, but rather using shaped light beams. On-demand spatial modulation of electron wavepackets is obtained via inelastic interaction with transversely shaped ultrafast light fields controlled by an external spatial light modulator. We illustrate this method for the cases of Hermite-Gaussian and Laguerre-Gaussian modulation and discuss their use in enhancing microscope sensitivity. Our approach dramatically widens the range of patterns that can be imprinted on the electron profile and greatly facilitates tailored electron-beam shaping.

Published
2022

16. Co-Design and Evaluation of the Feasibility and the Efficacy of a Multiple-Targeted Adapted Physical Activity Intervention to Promote Quality of Life, Well-Being and Physical Activity Levels in Pregnant Women: The 'WELL-DONE!' Study Protocol

Author

Virginia Bertini, Alice Masini, Dila Parma, Vincenza Leccese, Isotta Caravita, Sofia Marini, Rossella Messina, Davide Gori, Laura Dallolio, Marini S., Parma D., Masini A., Bertini V., Leccese V., Caravita I., Gori D., Messina R., and Dallolio L.

Subjects
medicine.medical_specialty, Geography, Planning and Development, Physical activity, TJ807-830, Management, Monitoring, Policy and Law, TD194-195, Focus group, Renewable energy sources, Quality of life, Intervention (counseling), medicine, GE1-350, exercise intervention, Exercise interven-tion, Protocol (science), Public health, Pregnancy, Environmental effects of industries and plants, Renewable Energy, Sustainability and the Environment, business.industry, medicine.disease, Environmental sciences, adapted physical activity, quality of life, Well-being, Physical therapy, co-design, pregnancy, Childbirth preparation classe, business, childbirth preparation classes
Abstract

Background: Regular physical activity (PA) practice during pregnancy offers health and fitness benefits for both mother and baby. Therefore, healthy pregnant women with no contraindications to exercise should be encouraged to perform PA. Nevertheless, their levels of PA are generally low. The aim of the WELL-DONE! Study is to co-design an adapted physical activity intervention (APAI) for pregnant women to include in childbirth preparation classes (CPCs) evaluating its feasibility and efficacy on quality of life (QoL), PA levels and other outcomes. Methods: A quasi-experimental study was divided in two progressive stages. First, APAI was developed in collaboration with pregnant women and midwives using focus groups; second, APAI’s efficacy was evaluated comparing two groups: the experimental group engaged in the CPCs integrated with 1 h/week of the APAI administered by midwives and the control group participating in the standard CPCs. Pre-post evaluation was carried out in three stages through questionnaires and tests. Data analysis involved the combination of qualitative and quantitative methodologies. Discussion: Findings from the WELL-DONE! Study will help to assess the feasibility, sustainability, and efficacy of incorporating APAI inside CPCs as a new public health strategy oriented to QoL, well-being, and PA level improvements.

Published
2021

17. I contratti di lavoro. Subordinati e autonomi

Author

L. Fiorillo, M. Lamberti, A. Lassandari, V. Leccese, F. Lunardon, A. Perulli, P. Tullini, Fiorillo, L., Lamberti, M., Lassandari, A., Leccese, V., Lunardon, F., Perulli, A., and Tullini, P.

Published
2021

18. L. 20 maggio 1970, n. 300 art. 1

Author

Covelli, R, Del Punta, R, Scarpelli, F, Marrucci, M, Rausei, P, Alessi, C, Alvino, I, Amoriello, L, Andreani, A, Angelini, L, Avio, A, Battistelli, S, Borzaga, M, Buoso, S, Carmerlengo, Q, Casale, D, Chiaromonte, W, Colosimo, C, Coraza, L, Corso, S, Corti, M, Covelli, R, Delogu, A, Diamanti, R, Donini, A, Failla, A, Faleri, C, Falsone, M, Forlivesi, M, Frigo, P, Furlan, F, Gadaleta, F, Gaetani, M, Ghitti, C, Giaconi, M, Giasanti, L, Giustiniani, M, Guadagno, S, Imberti, L, Imbriaci, S, Ingrao, A, Lanfranchi, E, Lazzari, C, Lazzeroni, L, Leccese, V, Lozito, M, Magi, E, Mainardi, S, Malzani, F, Marazza, M, Marino, D, Mocella, M, Monaco, M, Moro, G, Mortillaro, G, Natullo, G, Navilli, M, Negri, A, Negri, G, Novella, M, Occhino, A, Pallini, M, Pascucci, P, Pino, G, Pinto, V, Putaturo Donati, F, Ravelli, Renga, S, Renzi, S, Rescigno, S, Riccio, A, Rota, A, Rovere, V, Salazar, P, Sartori, A, Schiavone, R, Schiuma, D, Scorcelli, R, Sileoni, S, Sonnati, S, Stolfa, A, Tarquini, E, Toffoletto, F, Tomassetti, P, Tullini, P, Vallauri, M, Varva, S, Vernia, A, Villa, E, Visonà, S, Volpe, D, and Zicchittu, P

Subjects
Statuto dei lavoratori, Libertà di opinione, Dignità, Diritto del lavoro, IUS/07 - DIRITTO DEL LAVORO
Published
2020

19. AUditive Direct in Utero Observation (AUDIO): A Randomized Controlled Trial for a Prenatal Demonstration of Fetal Hearing

Author

Elena Contro, Nadia Rimondi, Antonio Farina, Danila Morano, Vincenza Leccese, Laura Larcher, Larcher L., Farina A., Morano D., Rimondi N., Leccese V., and Contro E.

Subjects
Medicine (General), Clinical Biochemistry, Prenatal diagnosis, Article, Group B, law.invention, Auditive stimulu, R5-920, Randomized controlled trial, law, medicine, Cardiotocography, auditive stimulus, Congenital hypoacusi, Fetus, medicine.diagnostic_test, business.industry, CTG, Fetuse, In utero, Anesthesia, Fetal movement, fetuses, Gestation, congenital hypoacusis, business, RCT
Abstract

Introduction: The objective of this randomized controlled study was to demonstrate whether acoustic stimulation in utero is associated with fetal reactivity which is documentable by cardiotocography. Materials and methods: A monocentric randomized controlled trial was performed at a single university tertiary hospital between September 2016 and July 2017. This study was registered as a randomized clinical trial on clinicaltrail.gov (registration number NCT04622059). Unselected pregnancies at term of gestation were consecutively recruited for the purpose of this study. After 10 min of normal cardiotocography without accelerations (non-stress-test with a basal frequency between 110 and 150 beats/min, normal variability between 6 and 15 b/min, no accelerations, and no fetal movements), fetuses were randomized at a 1:1 ratio to either of the two groups. Fetuses in group A (n = 105) received acoustic stimulation after 10 min from the beginning of the CTG, whereas fetuses in group B received no stimulation (n = 105). The outcome variables investigated were the lapse of time between the beginning of the CTG and the occurrence of the first acceleration, and the lapse of time between the beginning of the CTG and the first fetal movement noticed. Results: The lapse of time between the beginning of the CTG and the occurrence of the first acceleration was significantly shorter in the group with acoustic stimulation compared to the other group (14.87 ± 5.01 vs. 21.90 ± 6.94 min, p-value &lt, 0.001 log-rank test). Similarly, the lapse of time between the beginning of the CTG and the occurrence of the first fetal movement was significantly shorter in group A compared to group B (17.77 ± 7.62 vs. 23.28 ± 7.61 min, p-value &lt, 0.001, log-rank test). Fetal cardiac acceleration and the occurrence of a fetal movement during the first 20 min of the CTG were more frequently recorded in group A compared to group B (respectively, 15% vs. 5% and 20% vs. 8%). Conclusion: This RCT showed an early fetal reaction following auditive stimulus, documentable by cardiotocography. Further research is needed to investigate a possible role of acoustic stimulation in utero for the prenatal diagnosis of congenital hypoacusis.

Published
2021

20. Le tensioni del sistema di relazioni industriali e la riforma della rappresentanza

Author

SCARPELLI, FRANCO, Mariucci, L, Ferraro, G, Gragnoli, E, Lassandari, A, Scarponi, S, Leccese, V, Gottardi, G, Bellavista, A, Maresca, A, Zoppoli, A, Scarpelli, F, Bavaro, V, Carabelli, U, Camusso, S, Foccillo, A, Marignani, C, and Vernola, J

Subjects
sindacato, contrattazione collettiva, rappresentanza, IUS/07 - DIRITTO DEL LAVORO
Abstract

Il contributo muove dai problemi di recente frammentazione del sistema di relazioni industriali italiano, per trarne la convinzione che sia oggi più motivato un intervento legislativo sulla contrattazione. Vengono però evidenziati alcuni snodi di difficile soluzione, affrontati in modo diverso dai progetti di legge elaborati da alcuni gruppi di studiosi e dalla principale organizzazione sindacale.

Published
2016

21. Revisiting the Excitation of the Low-Lying ^{181m}Ta Isomer in Optical Laser-Generated Plasma.

Author

Gargiulo S, Madan I, Truc B, Usai P, Beeks K, Leccese V, Vanacore GM, and Carbone F

Abstract

The excitation of the ^{181m}Ta isomer in the laser-plasma scenario was claimed to have been observed more than two decades ago. However, the reported experimental findings-and the respective high excitation rate-were later questioned as they could not be reproduced theoretically. The controversy has remained open ever since. In this work, we reinvestigate both theoretically and experimentally the ^{181m}Ta nuclear excitation in an optical laser-generated plasma. Experimentally we have found no evidence for such an excitation process as consistently predicted by previous and our theoretical models.

Published
2024
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22. Application of the COM-B Framework to Understand Facilitators and Barriers for Practising Physical Activity among Pregnant Women and Midwives Participating in the WELL-DONE! Study.

Author

Marini S, Messina R, Masini A, Scognamiglio F, Caravita I, Leccese V, Soldà G, Parma D, Bertini V, Scheier LM, and Dallolio L

Abstract

Regular physical activity (PA) is protective and reduces disease burden but remains a challenge for pregnant women (PW). According to the World Health Organization (WHO) guidelines, PW without contraindications should practice 150 min of moderate PA per week. Nonetheless, PA levels are concerningly low among PW. The aim of this study was to investigate PW's and midwives' perceptions regarding PA and recommended guidelines, and use this information to inform future health promotion strategies. We recruited 10 PW and 10 midwives to participate in online focus groups conducted between July 2020 and April 2021. Focus group probes and data analysis were guided by the COM-B (capability, opportunity, motivation-behaviour) framework. The majority of the sample had already practised PA, recognized the importance of PA during pregnancy, and considered the WHO guidelines reasonable. Notwithstanding, PW wanted more specific instruction on PA and desired opportunities to practice. Additional barriers reported by PW included low self-efficacy and lack of motivation. Midwives considered the lack of specific knowledge and confidence in managing PA as the main obstacles. The current findings suggest that PW and midwives need specific training in PA to overcome both psychological and physical barriers. Midwives play a vital role in educating and encouraging PA among PW.

Published
2023
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23. [Treatment-resistant depression. From classification to new therapies.]

Author

Paganin W, Signorini S, Leccese V, and Sciarretta A

Subjects
Humans, Quality of Life, Transcranial Direct Current Stimulation, Ketamine therapeutic use, Depressive Disorder, Major
Abstract

Aims: This paper aims to investigate the advances in recent years in the recognition and therapy of treatment-resistant depression starting from the concepts of: depressive disorder, resistance and pseudoresistance to drug treatment in depression, and appropriate treatments of treatment-resistant depression., Methods: An extensive research was carried out on scientific databases such as: PubMed, PsychInfo and Cochrane Library, until May 2022, using the keywords "major depression", "treatment-resistant depression", "staging", "instrumental therapies for resistant depression", "esketamine" and "psilocybin"., Results: Subjects who do not respond to antidepressants show a form of treatment resistance that requires an approach with additional pharmacological and/or instrumental therapies. Recently, esketamine and psilocybin are of particular interest among clinicians, and instrumental treatments such as: vagus nerve stimulation, deep brain stimulation, repetitive transcranial magnetic stimulation, transcranial direct current stimulation, epidural cortical stimulation, and electro convulsive therapy, are being added to them., Discussion and Conclusions: Treatment-resistant depression has increasingly become a public health problem due to the significant number of relapses, hospitalizations and mortality it entails, with increased demand for the use of more drugs, therapeutic resources by health services, and loss of quality of life for patients. Treatment-resistant depression needs to be addressed through the creation of dedicated study protocols. Future research should focus on the need to establish operational, valid and appropriate criteria, both on the psychopathological, clinical governance and therapeutic levels, focusing on the latest therapies in order to provide reliable data on the benefits, risks and costs associated with their use.

Published
2022
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24. Ultrafast Transverse Modulation of Free Electrons by Interaction with Shaped Optical Fields.

Author

Madan I, Leccese V, Mazur A, Barantani F, LaGrange T, Sapozhnik A, Tengdin PM, Gargiulo S, Rotunno E, Olaya JC, Kaminer I, Grillo V, de Abajo FJG, Carbone F, and Vanacore GM

Abstract

Spatiotemporal electron-beam shaping is a bold frontier of electron microscopy. Over the past decade, shaping methods evolved from static phase plates to low-speed electrostatic and magnetostatic displays. Recently, a swift change of paradigm utilizing light to control free electrons has emerged. Here, we experimentally demonstrate arbitrary transverse modulation of electron beams without complicated electron-optics elements or material nanostructures, but rather using shaped light beams. On-demand spatial modulation of electron wavepackets is obtained via inelastic interaction with transversely shaped ultrafast light fields controlled by an external spatial light modulator. We illustrate this method for the cases of Hermite-Gaussian and Laguerre-Gaussian modulation and discuss their use in enhancing microscope sensitivity. Our approach dramatically widens the range of patterns that can be imprinted on the electron profile and greatly facilitates tailored electron-beam shaping., Competing Interests: The authors declare no competing financial interest., (© 2022 The Authors. Published by American Chemical Society.)

Published
2022
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25. AUditive Direct in Utero Observation (AUDIO): A Randomized Controlled Trial for a Prenatal Demonstration of Fetal Hearing.

Author

Larcher L, Farina A, Morano D, Rimondi N, Leccese V, and Contro E

Abstract

Introduction: The objective of this randomized controlled study was to demonstrate whether acoustic stimulation in utero is associated with fetal reactivity which is documentable by cardiotocography., Materials and Methods: A monocentric randomized controlled trial was performed at a single university tertiary hospital between September 2016 and July 2017. This study was registered as a randomized clinical trial on clinicaltrail.gov (registration number NCT04622059). Unselected pregnancies at term of gestation were consecutively recruited for the purpose of this study. After 10 min of normal cardiotocography without accelerations (non-stress-test with a basal frequency between 110 and 150 beats/min, normal variability between 6 and 15 b/min, no accelerations, and no fetal movements), fetuses were randomized at a 1:1 ratio to either of the two groups. Fetuses in group A (n = 105) received acoustic stimulation after 10 min from the beginning of the CTG, whereas fetuses in group B received no stimulation (n = 105). The outcome variables investigated were the lapse of time between the beginning of the CTG and the occurrence of the first acceleration, and the lapse of time between the beginning of the CTG and the first fetal movement noticed., Results: The lapse of time between the beginning of the CTG and the occurrence of the first acceleration was significantly shorter in the group with acoustic stimulation compared to the other group (14.87 ± 5.01 vs. 21.90 ± 6.94 min, p -value < 0.001 log-rank test). Similarly, the lapse of time between the beginning of the CTG and the occurrence of the first fetal movement was significantly shorter in group A compared to group B (17.77 ± 7.62 vs. 23.28 ± 7.61 min, p -value < 0.001, log-rank test). Fetal cardiac acceleration and the occurrence of a fetal movement during the first 20 min of the CTG were more frequently recorded in group A compared to group B (respectively, 15% vs. 5% and 20% vs. 8%)., Conclusion: This RCT showed an early fetal reaction following auditive stimulus, documentable by cardiotocography. Further research is needed to investigate a possible role of acoustic stimulation in utero for the prenatal diagnosis of congenital hypoacusis.

Published
2021
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26. Natural Products for Neurocognitive Disorders

Author

Servello A, Leccese V, Ettorre E, and Huang X

Abstract

Neurocognitive disorders are devastating. In 2016, 43.8 million people were estimated to have Alzheimer’s disease worldwide. By 2050, this figure is expected to rise by 56%. Despite the extreme importance of the disease, the weapons available to us to combat it are very scarce. Natural substances may be a worthwhile option for the treatment and management of neurocognitive disorders. Some of these natural products have been shown to be capable of positively impacting memory, behavior, and functions of patients with Alzheimer’s disease. These substances act on the disease mainly through antioxidant properties, the ability to eliminate oxygen radicals, the capacity to influence cell survival and programmed cell death, and the potential to condition amyloidogenesis. This chapter provides an overview of our current knowledge on the potential of natural products to be effective neuroprotective agents for Alzheimer’s disease. Current evidence on Ginkgo biloba, bacopia, resveratol, curcumin, quercetin, kaempferol, capsaicin, and berberine, along with their adverse effects and drug interactions are discussed., (Copyright: The Authors.)

Published
2020
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27. Buprenorphine and methadone maintenance treatment of heroin addicts preserves immune function.

Author

Sacerdote P, Franchi S, Gerra G, Leccese V, Panerai AE, and Somaini L

Subjects
Adult, Female, Humans, Immune System drug effects, Immunocompetence drug effects, Immunocompetence immunology, Interferon-gamma metabolism, Interleukin-2 metabolism, Interleukin-4 metabolism, Male, T-Lymphocytes drug effects, T-Lymphocytes immunology, T-Lymphocytes metabolism, Tumor Necrosis Factor-alpha metabolism, Analgesics, Opioid administration & dosage, Buprenorphine administration & dosage, Heroin Dependence drug therapy, Heroin Dependence immunology, Methadone administration & dosage
Abstract

Opiate addiction influences many physiological functions including immune responses. The objective of this study was to investigate the immune system function in heroin addicted patients submitted to methadone or buprenorphine maintenance treatment compared to untreated heroin addicts and healthy controls. Four groups were studied: group A included nine heroin addicted subjects, who were still injecting heroin; groups B and C were composed of 12 patients previously addicted to heroin, being treated with methadone (mean dosage 58+/-12.7 mg/day) or buprenorphine (mean dose 9.3+/-2.3mg/day) since at least 6 months; group D was composed of 15 sex and age matched healthy controls. Lymphoproliferation and peripheral mononuclear cell cultures production of the Th1 cytokines IL-2 and IFN-gamma, the Th2 cytokine IL-4, and of the pro-inflammatory cytokine TNF-alpha were evaluated in all the patients and controls. PHA-lymphoproliferation was lower in untreated heroin addicts than in controls, while it was normal in methadone and buprenorphine treated patients. An altered Th1/Th2 balance, characterized by reduced IL-4, IFN-gamma and TNF-alpha but normal IL-2 levels, was present in untreated heroin addicted subjects, while the Th1/Th2 balance was well conserved in the methadone and buprenorphine groups. These findings suggest that the immune system abnormalities in heroin addicted patients can be restored to almost normal values by controlled treatment with methadone and buprenorphine.

Published
2008
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28. Adequacy of solute and water removal in children treated with nightly intermittent peritoneal dialysis.

Author

Edefonti A, Picca M, Ghio L, Bassi S, Cattarelli D, and Leccese V

Subjects
Body Water metabolism, Child, Creatinine metabolism, Humans, Kidney Failure, Chronic metabolism, Kidney Failure, Chronic therapy, Peritoneal Dialysis, Continuous Ambulatory, Peritoneum metabolism, Urea metabolism, Dialysis Solutions, Peritoneal Dialysis
Abstract

Nightly intermittent peritoneal dialysis (NIPD) is an automated form of intermittent peritoneal dialysis which has potential medical and psychosocial advantages in comparison with CAPD/CCPD due to the lack of daytime exchanges. Data on solute/water removal in children on NIPD are nevertheless scarce, so that no clear indications for NIPD can yet be formulated in pediatric age. For this reason, 12 patients, mean age 10.49 +/- 5.81, mean body weight 23.73 +/- 10.92, with a residual creatinine clearance 1.70 +/- 2.30 ml/min/1.73 sqm, on NIPD for 14.7 +/- 5.4 months, underwent clearance studies over 3 days. Mean dialysis infusion volume was 460.08 +/- 196.30 ml/kg/day, with 10.33 +/- 1.22 h dialysis time. Peritoneal creatinine and urea clearances were 6.36 +/- 2.96 and 8.49 +/- 3.35 1/day/1.73 sqm, respectively. Combined creatinine and urea clearances averaged 6.12 +/- 2.21 and 6.96 +/- 2.16 ml/min/1.73 sqm, resulting in serum creatinine and urea values of 7.78 +/- 1.90 and 115.58 +/- 29.93 mg/dl, respectively. Ultrafiltration rate was 16.94 +/- 16.34 ml/g glucose absorbed. NIPD provided similar or improved solute and water clearances compared with those reported in children and adults on CAPD/CCPD, without inconvenient long periods in bed. These data indicate that NIPD is a suitable treatment in pediatric end-stage renal disease.

Published
1992

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