12 results on '"Lecca ME"'
Search Results
2. Counseling in Primary Care Improves Depression and Quality of Life
- Author
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Carta, MG, primary, Petretto, D, additional, Adamo, S, additional, Bhat, KM, additional, Lecca, ME, additional, Mura, G, additional, Carta, V, additional, Angermeyer, M, additional, and Moro, MF, additional
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- 2012
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3. Study on psychoeducation enhancing results of adherence in patients with schizophrenia (SPERA-S): study protocol for a randomized controlled trial
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Petretto, Dr, Preti, A, Zuddas, C, Veltro, F, Rocchi, Mb, Sisti, D, Martinelli, V, Carta, Mg, Masala, C, Alfa, Rita, Arcidiacono, E, Aguglia, E, Bonanni, E, Borea, M, Consolazione, M, De Giglio, P, DI ROSA, Antonio, Faravelli, C, Fioravanti, G, Fiori Nastro, P, Floris, A, Floris, F, Iannone, C, Iuso, S, La Verde, M, Laffranchini, L, Lecca, Me, Sauro, Cl, Magni, Lr, Margari, F, Marras, M, Marzano, L, Masotti, E, Matta, C, Minutolo, G, Moro, Mf, Mura, G, Nardini, M, Nicchiniello, I, Padalino, F, Papini, Mn, Pastore, A, Petito, A, Pioli, R, Porfiri, Gm, Pullara, A, Sancassiani, F, Seu, Mi, Stallone, V, Vinci, S, and Zappone, L.
- Subjects
Research design ,Health Knowledge, Attitudes, Practice ,Time Factors ,medicine.medical_treatment ,Medicine (miscellaneous) ,Adherence to pharmacotherapy ,Caregiver ,Falloon's method ,Family ,Psychoeducation ,Randomized controlled trial ,Schizophrenia ,law.invention ,Study Protocol ,Clinical Protocols ,Cost of Illness ,Recurrence ,law ,Surveys and Questionnaires ,Pharmacology (medical) ,Chromatography, High Pressure Liquid ,Intention to Treat Analysis ,Treatment Outcome ,Caregivers ,Italy ,Research Design ,Schizophrenic Psychology ,Family Relations ,Drug Monitoring ,Psychosocial ,Antipsychotic Agents ,medicine.medical_specialty ,Blinding ,Medication Adherence ,Pharmacotherapy ,Patient Education as Topic ,schizophrenia ,Psychological adjustment ,caregivers ,medicine ,Humans ,Psychiatry ,Psychiatric Status Rating Scales ,Intention-to-treat analysis ,business.industry ,Falloon’s method ,Supportive psychotherapy ,Physical therapy ,Feasibility Studies ,business - Abstract
Poor adherence to pharmacotherapy negatively affects the course and the outcome of schizophreniaspectrum psychoses, enhancing the risk of relapse. Falloon and coworkers developed a Psychoeducation Program aimed at improving communication and problem-solving abilities in patients and their families. This study set out to evaluate changes in adherence to pharmacotherapy in patients diagnosed with schizophrenia-spectrum psychoses, by comparing one group exposed to the Falloon Psychoeducation Program (FPP) with another group exposed to family supportive therapy with generic information on the disorders. 340 patients diagnosed with schizophrenia and related disorders according to standardized criteria from 10 participating units distributed throughout the Italian National Health System (NHS), will be enrolled with 1:1 allocation by the method of blocks of randomized permutations. Patients will be reassessed at 6, 12 and 18 months after start of treatment (duration: 6 months). The primary objective is to evaluate changes in adherence to pharmacotherapy after psychoeducation. Adherence will be assessed at three-month intervals by measuring blood levels of the primary prescribed drug using high pressure liquid chromatography, and via the Medication Adherence Questionnaire and a modified version of the Adherence Interview. Secondary objectives are changes in the frequency of relapse and readmission, as the main indicator of the course of the disorder. Enrolled patients will be allocated to the FPP (yes/no) randomly, 1:1, in a procedure controlled by the coordinating unit; codes will be masked until the conclusion of the protocol (or the occurrence of a severe negative event). The raters will be blind to treatment allocation and will be tested for blinding after treatment completion. Intention-to-treat will be applied in considering the primary and secondary outcomes. Multiple imputations will be applied to integrate the missing data. The study started recruitment in February 2013; the total duration of the study is 27 months. If the psychoeducation program proves effective in improving adherence to pharmacotherapy and in reducing relapse and readmissions, its application could be proposed as a standard adjunctive psychosocial treatment within the Italian NHS. Protocol Registration System of ClinicalTrials.gov NCT01433094 ; registered on 20 August 2011; first patient was randomized on 12 February 2013.
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4. The lifetime prevalence of bipolar disorders and the use of antidepressant drugs in bipolar depression in Italy.
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Carta MG, Aguglia E, Balestrieri M, Calabrese JR, Caraci F, Dell'osso L, Di Sciascio G, Drago F, Faravelli C, Lecca ME, Moro MF, Nardini M, Palumbo G, and Hardoy MC
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- 2012
5. Could an Innovative Training Program Including Contact Sports and Counseling Help Young People With Traits of Psychopathy and A History of School Dropout?
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Sancassiani F, Lecca ME, Pintus E, Moro MF, Caria R, Minerba L, Mela Q, Nardi AE, Machado S, d'Aloja E, Preti A, and Carta MG
- Abstract
Background: The aim was to assess the effects of a training program inclusive of contact sports and counseling on school dropout, quality of life (QoL) and psychopathologic symptoms in the youth with a history of school dropout and psychopathic personality traits., Methods: The Experimental Group (EG) consisted of 32 subjects (male 90.6%; age 19.6±4.3 years); the Control Group (CG) consisted of an equal number matched for gender and age with the same psychological features. At the beginning of the experimental Training Program (T0), both cohorts were assessed by a diagnostic psychiatric interview (SCID ANTAS), the Short Form Health Survey (SF-12) to evaluate QoL, the Psychopathy Checklist - Revised (PCL-R) for the assessment of psychopathic traits, the Self Reporting Questionnaire (SRQ) to measure general psychopathology. At the end of the program (T1), the coorths were evaluated by SF-12 and SRQ., Results: Twenty-seven subjects in the EG (84.4%) completed the course and underwent the evaluation at T1. The SF-12 score significantly increased from T0 to T1 in both groups, albeit this was more evident in the EG than in the CG, owing to an interaction between time and group. SRQ score significantly decreased in the EG from T0 to T1, while in the CG it did not, although the interaction between time and group was not significant., Conclusion: The experimental training program was effective in improving QoL and countering school dropout in young citizens with psychopathic traits. Further studies are needed to clarify if such results are due to a relationship between the practical tasks approach including contact sports and an improvement in mentalization processes.
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- 2019
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6. Patients with carotid atherosclerosis who underwent or did not undergo carotid endarterectomy: outcome on mood, cognition and quality of life.
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Carta MG, Lecca ME, Saba L, Sanfilippo R, Pintus E, Cadoni M, Sancassiani F, Moro MF, Craboledda D, Lo Giudice C, Finco G, Musu M, and Montisci R
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- Affect physiology, Age Factors, Aged, Cohort Studies, Female, Humans, Italy, Male, Middle Aged, Neuropsychological Tests, Severity of Illness Index, Treatment Outcome, Carotid Artery Diseases diagnosis, Carotid Artery Diseases psychology, Carotid Artery Diseases surgery, Cognition physiology, Depressive Disorder diagnosis, Depressive Disorder etiology, Depressive Disorder physiopathology, Endarterectomy, Carotid adverse effects, Endarterectomy, Carotid methods, Endarterectomy, Carotid psychology, Quality of Life
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Background: To compare the six-month outcome on mood, cognition and quality of life (QoL) in patients with severe carotid atherosclerosis (CA) who underwent carotid endarterectomy (CEA) with subjects who refused treatment., Methods: Cohort study on consecutive inpatients with CA (stenosis ≥ 50 %) (N = 46; age 72.56 ± 7.26; male 65.2 %). Intervention cohort: subjects who decided to undergo CEA (N = 35); Control cohort patients who refused CEA (N = 11). DSM-IV-Psychiatric diagnosis made by clinicians using interviews, QoL measured by Short Form Health Survey (SF-12); cognitive performance by WAIS Intelligent Coefficient (IC)., Results: The study showed a better improvement during six months in Overall IC, Performance IC and Verbal IC in the group that underwent CEA. QoL in the two cohorts did not reach statistical significance. Percentages of patients who improved in the CEA group were significantly higher with regard to Overall and Verbal IC scores, and at the limits of statistical significance in Performance IC. The differences of subject with improvement in SF-12 score in the two groups did not reach statistical significance. Ages below 68 were found to be determinant of a good outcome in Overall IC score. Limit: study conducted with a small sample size., Conclusions: Patients with severe carotid atherosclerosis who underwent CEA enhanced their cognitive performance.
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- 2015
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7. Outcomes of discharged females versus those waiting for discharge from Vlore Psychiatric Hospital (Albania).
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Carta MG, Agaj A, Harapej E, Lecca ME, Xhelili G, Altoé G, Mura G, Moro MF, and Angermeyer MC
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- Adult, Albania, Case-Control Studies, Female, Follow-Up Studies, Halfway Houses, Humans, Middle Aged, Psychotic Disorders drug therapy, Deinstitutionalization, Hospitalization, Hospitals, Psychiatric, Outcome Assessment, Health Care methods, Outcome Assessment, Health Care statistics & numerical data, Patient Discharge
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Background: This study examines the psychosocial outcomes of women discharged from the Vlore Psychiatric Hospital in Albania., Methods: The study was designed as a controlled, not randomized, follow-up study. It included 16 women diagnosed with psychosis who were discharged from a psychiatric hospital to live in group homes in the community. The control group included 20 women diagnosed with psychosis who lived at the psychiatric hospital while awaiting discharge. All subjects were assessed twice using the HoNOS-Rome tool, at the start of the study (T0) and 12 months later (T1)., Results: Both groups showed an improvement in the HoNOS total score between T0 and T1 (p < .001). This improvement was significantly larger in the Home group compared to the Hospital group (p = .014). An item-level analysis indicated a significantly greater improvement in the Home group on items 11 (autonomy), 12 (work), 16 (family) and 18 (goals)., Conclusions: Projects for social inclusion of people suffering from psychosis must design living spaces that offer viable alternatives to psychiatric hospitals. This study also documents the efforts in the Vlore region of Albania to follow European standards of mental health care.
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- 2013
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8. Decreases in depression over 20 years in a mining area of Sardinia: due to selective migration?
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Carta MG, Mura G, Lecca ME, Moro MF, Bhat KM, Angermeyer MC, Hardoy M, and Akiskal HS
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- Adolescent, Adult, Age Distribution, Aged, Female, Health Surveys, Humans, Incidence, Italy epidemiology, Male, Middle Aged, Prevalence, Research Report, Sex Distribution, Young Adult, Depression epidemiology, Depressive Disorder, Major epidemiology, Human Migration, Mining
- Abstract
Background: The objective of the study was to determine if community surveys, conducted 3 times over a period of 20 years in a small district of Sardinia (Italy), confirm the increase in depressive disorders reported in the recent literature., Methods: Three community surveys were carried out on randomized samples of the same Sardinian mining area in 1988, 1998 and 2008. The surveys were conducted using the interview "Present State Examination" in 1988 (depression diagnosed with ICD-IX) and the CIDI-S in 1998 and 2008 (major depression diagnosed with ICD-X). The three surveys produced estimates of one-month prevalence and of lifetime prevalence in 1998 and 2008., Results: Our work found a substantial decrease in depressive disorders from the survey conducted in 1998 to the survey in 2008 using a similar methodology, except in the youngest age group, which showed an increase in the rate. A decrease in the frequency of depressive disorders compared to what was found 20 years ago was also observed. However, in this case the comparison is more problematic because of use of different diagnostic systems., Discussion: The research seems to show a decrease in depressive disorders over the past two decades. While the small population examined makes it difficult to generalize the overall findings, this study suggests that the hypothesis of an increase in the incidence of depressive disorders since the 1980s in western countries, should have exceptions. A complex interaction between socio-economic (mining closure and large migration) and biological factors (possible selective migration) is likely to influence changes in the prevalence of mood disorders. However, due to certain limitations of this study, this hypothesis may be considered from a heuristic perspective., (Copyright © 2012 Elsevier B.V. All rights reserved.)
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- 2012
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9. Quality of life and urban / rural living: preliminary results of a community survey in Italy.
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Carta MG, Aguglia E, Caraci F, Dell'Osso L, Di Sciascio G, Drago F, Del Giudice E, Faravelli C, Hardoy MC, Lecca ME, Moro MF, Calò S, Casacchia M, Angermeyer M, and Balestrieri M
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Background: The purpose of this population-based study is to examine the association between subjective quality of life and rural/urban residence in six Italian regions, including age and gender into the analysis., Study Design: community survey., Study Population: Samples stratified according to sex and age, drawn from municipal records., Sample Size: 4999 people 18 years and older, from seven communities within six regions of Italy., Tools: Ad-hoc form to assess basic demographic data; SF-12. Interviewers were trained psychologists or medical doctors., Results: 3398 subjects were interviewed (68% of recruited sample). The mean score of SF-12 in the overall sample was 38.4±6.1, SF-12 was higher in men than in in women (38.4±6.1 vs 37.5±5.9 F=99.18, df 1, 3396, 3397, p<0.0001); SF-12 score decreased from the youngest to the oldest age group, with significant differences between all ages groups; men showed higher scores in all age groups. The urban/rural difference of mean scores of SF-12 did not achieve statistical significance in women. Young men with urban residence had higher SF-12 scores than their counterparts with rural residence. Maen aged 65 years and older with rural residence showed, by contrast, higher scores than men from the same age group with urban residence., Conclusions: Men show a higher subjective quality of life than women. Subjective quality of life decreases with age in both genders.Men are more sensitive to urban/rural residence than women.Young men live better in cities, elderly men better in rural areas.
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- 2012
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10. Sub-threshold depression and antidepressants use in a community sample: searching anxiety and finding bipolar disorder.
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Carta MG, Tondo L, Balestrieri M, Caraci F, Dell'osso L, Di Sciascio G, Faravelli C, Hardoy MC, Lecca ME, Moro MF, Bhat KM, Casacchia M, and Drago F
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- Adolescent, Adult, Aged, Anxiety Disorders complications, Anxiety Disorders drug therapy, Benzodiazepines therapeutic use, Bipolar Disorder complications, Depression complications, Depression diagnosis, Depression epidemiology, Female, Health Surveys statistics & numerical data, Humans, Italy epidemiology, Male, Middle Aged, Prevalence, Psychiatric Status Rating Scales statistics & numerical data, Antidepressive Agents therapeutic use, Anxiety Disorders epidemiology, Bipolar Disorder epidemiology, Depression drug therapy, Residence Characteristics statistics & numerical data
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Background: To determine the use of antidepressants (ADs) in people with sub-threshold depression (SD); the lifetime prevalence of mania and hypomania in SD and the link between ADs use, bipolarity and anxiety disorders in SD., Study Design: community survey., Study Population: samples randomly drawn, after stratification from the adult population of municipal records., Sample Size: 4999 people from seven areas within six Italian regions. Tools: Questionnaire on psychotropic drug consumption, prescription; Structured Clinical Interview NP for DSM-IV modified (ANTAS); Hamilton Depression Rating Scale (HAM-D); Mood Disorder Questionnaire (MDQ); Short Form Health Survey (SF-12). SD definition: HAM-D > 10 without lifetime diagnosis of Depressive Episode (DE)., Results: SD point prevalence is 5.0%. The lifetime prevalence of mania and hypomania episodes in SD is 7.3%. Benzodiazepines (BDZ) consumption in SD is 24.1%, followed by ADs (19.7%). In SD, positive for MDQ and comorbidity with Panic Disorder (PD) or Generalized Anxiety Disorders (GAD) are associated with ADs use, whereas the association between a positive MDQ and ADs use, without a diagnosis of PD or GAD, is not significant. Only in people with DE the well-being (SF-12) is higher among those using first-line antidepressants compared to those not using any medication. In people with SD no significant differences were found in terms of SF-12 score according to drug use., Conclusions: This study suggests caution in prescribing ADs to people with SD. In people with concomitant anxiety disorders and SD, it should be mandatory to perform a well-designed assessment and evaluate the presence of previous manic or hypomanic symptoms prior to prescribing ADs.
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- 2011
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11. Benefits of exercise with mini tennis in intellectual disabilities: effects on body image and psychopathology.
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Hardoy MC, Seruis ML, Floris F, Sancassiani F, Moro MF, Mellino G, Lecca ME, Adamo S, and Carta MG
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The present study is aimed at evaluating the efficacy of an introductory mini tennis programme as a therapeutic aid in the psychosocial rehabilitation of participants affected by mild/moderate intellectual disability in semi-residential care.Two groups (N=12) of participants diagnosed with intellectual disability, one of which followed the mini tennis rehabilitation programme, were compared at time t0, t1 (after 2 months) and t2 (after 6 months).Psychopathological status was assessed by means of the Italian version of the Assessment and Information Rating Profile (AIRP). Motor coordination, lateral dominance and body scheme were assessed by means of structured tools.Psychopathological total scores showed a statistically significant decrease in the experimental group in comparison with the control group. A statistical decrease in the group with the mini tennis rehabilitation programme was found also in the anxiety sub-scale while the sub-scales schizophrenia, depression, adjustment disorder, personality problems, somatoform disorders and psychosexual disorders did not reach any statistical difference between groups.A statistically significant increase in the visuo manual coordination was highlighted in the experimental versus the control group. No statistically significant differences were reported with regard to general movement skills, dynamic balance and coordination.In spite of the limitations of this study, the results obtained are encouraging and suggest the potential efficacy of mini tennis as an auxiliary aid in rehabilitation programmes, particularly to improve visuo manual coordination skills and to boost the patient/participants' self esteem. These findings warrant confirmation by further research studies.
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- 2011
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12. The use of antidepressant drugs and the lifetime prevalence of major depressive disorders in Italy.
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Carta MG, Aguglia E, Bocchetta A, Balestrieri M, Caraci F, Casacchia M, Dell'osso L, Sciascio GD, Drago F, Faravelli C, Lecca ME, Moro MF, Morosini PL, Nardini M, Palumbo G, and Hardoy MC
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Background: The increased use of antidepressant drugs (ADs) improved the response to the needs of care although some community surveys have shown that subjects without lifetime psychiatric diagnosis (anxiety/depression) used ADs., Objectives: To evaluate the appropriateness and amount of prescription of psychotropic drugs in people with lifetime diagnosis of Major Depressive Disorder (MDD) by means of community survey with a semi-structured interview as a diagnostic instrument, administered by clinicians., Study Design: community survey., Study Population: samples randomly drawn, after stratification from the adult population of municipal records., Sample Size: 4.999 people were drawn in 7 centres of 6 Italian regions., Tools: questionnaire on psychotropic drug consumption, prescription, health services utilization; Structured Clinical Interview for DSM-IV modified (ANTAS); Training: interviewers were trained psychologists or medical doctors., Results: 3.398 subjects were interviewed (68% of the recruited sample). The lifetime prevalence of DSM-IV MDD was 4.3% in males and 11.5% in females; antidepressant drugs were taken by 4.7% of subjects, 2.9% male and 5.9% female. 38% of males and 57% of females with lifetime diagnosis of MDD were taking ADs., Conclusions: Compared with studies using lay interviewers and structured tools the prevalence of the MDD was quite lower; ADs use was higher and tallied well with the data regarding antidepressant sales in Italy; the correspondence between lifetime diagnosis of MDD and ADs use was closer.
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- 2010
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