34 results on '"Lebanese University - LU (LEBANON)"'
Search Results
2. In-and out-plane transport properties of chemical vapor deposited TiO 2 anatase films
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A Miquelot, Nita Dragoe, Stéphanie Roualdes, Michel Nakhl, Joelle Bassil, Loraine Youssef, Christina Villeneuve-Faure, Nathalie Prud’homme, M. Zakhour, Amr A. Nada, Vincent Rouessac, Constantin Vahlas, Centre interuniversitaire de recherche et d'ingenierie des matériaux (CIRIMAT), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), Institut Européen des membranes (IEM), Centre National de la Recherche Scientifique (CNRS)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM), Diélectriques Solides et Fiabilité (LAPLACE-DSF), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), Institut de Chimie du CNRS (INC)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Lebanese University [Beirut] (LU), Centre National de la Recherche Scientifique - CNRS (FRANCE), Egyptian Petroleum Research Institute - EPRI (EGYPT), Ecole Nationale Supérieure de Chimie de Montpellier - ENSCM (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Paris-Saclay (FRANCE), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), and Université de Montpellier (FRANCE)
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Thim film ,Electron mobility ,Anatase ,Materials science ,thin film ,Matériaux ,PECVD ,02 engineering and technology ,Dielectric ,Chemical vapor deposition ,[SPI.MAT]Engineering Sciences [physics]/Materials ,transport properties ,Plasma-enhanced chemical vapor deposition ,Electrical resistivity and conductivity ,TiO2 ,General Materials Science ,Metalorganic vapour phase epitaxy ,Thin film ,020502 materials ,Mechanical Engineering ,C-AFM ,[CHIM.MATE]Chemical Sciences/Material chemistry ,0205 materials engineering ,Chemical engineering ,Mechanics of Materials ,Transport properties ,MOCVD - Abstract
International audience; Due to their polymorphism, TiO 2 films are quintessential components of state-ofthe-art functional materials and devices for various applications from dynamic random access memory to solar water splitting. However, contrary to other semiconductors/dielectric materials, the relationship between structural/morphological and electrical properties at the nano and microscales remains unclear. In this context, the morphological characteristics of TiO 2 films obtained by metalorganic chemical vapor deposition (MOCVD) and plasma-enhanced chemical vapor deposition (PECVD), the latter including nitrogen doping, are investigated and they are linked to their in-and out-plane electrical properties. A transition from dense to tree-like columnar morphology is observed for the MOCVD films with increasing deposition temperature. It results in the decrease in grain size and the increase in porosity and disorder, and subsequently, it leads to the decrease in lateral carrier mobility. The increase in nitrogen amount in the PECVD films enhances the disorder in their pillar-like columnar morphology along with a slight increase in density. A similar behavior is observed for the out-plane current between the low temperature MOCVD films and the undoped PECVD ones. The pillar-like structure of the latter presents a lower in-plane resistivity than the low temperature MOCVD films, whereas the out-plane resistivity is lower. The treelike columnar structure exhibits poor in-and out-plane conductivity properties, whereas pillar-like and dense TiO 2 exhibits similar in-and out-plane conductivities even if their morphologies are noticeably different.
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- 2021
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3. Managing and controlling COVID-19 in Lebanon using the Internet of Things and Artificial Intelligence
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Wehbe, Arz, Azoury, Chadi, Baron, Claude, Vingerhoeds, Rob A., Institut National des Sciences Appliquées de Toulouse - INSA (FRANCE), Institut Supérieur de l'Aéronautique et de l'Espace - ISAE-SUPAERO (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Lebanese Canadian University - LCU (LEBANON), Laboratoire d'Analyse et d'Architecture des Systèmes - LAAS (Toulouse, France), and Département d'Ingénierie des Systèmes Complexes - DISC (Toulouse, France)
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Autre ,Artificial Intelligence ,Internet of Things ,Machine learning ,COVID-19 Lebanon - Abstract
COVID-19 recently grew as a major problem worldwide and is considered the pandemic of the third century. Among the issues in dealing with this pandemic is the urgency, the bad communication, the decentralization of decision and the mismanagement of this crisis. In order to address these issues, the authors propose the use of Internet of Things and Artificial Intelligence. The Internet of Things proposes several solutions to the aforementioned problems, while using the Genetic Algorithm in AI to calibrate the proposed generalized SEIR mathematical model. This model, when calibrated to the existent recorded and confirmed data in Lebanon, will help predict the number of infected individuals. Thus, it will better prepare for the fight with the virus.
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- 2021
4. Biochemical Composition of Cumin Seeds, and Biorefining Study
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Philippe Evon, Zeinab Saad, Bouchra Sayed-Ahmad, Akram Hijazi, Muriel Cerny, Othmane Merah, Thierry Talou, Sarah Grivot, Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut national de recherche pour l'agriculture, l'alimentation et l'environnement - INRAE (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Chimie Agro-Industrielle (CAI), Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Universitaire de Technologie - Paul Sabatier (IUT Paul Sabatier), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), and Lebanese University and National Polytechnic Institute of Toulouse
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0106 biological sciences ,Cuminum ,[SDV]Life Sciences [q-bio] ,Phytochemicals ,lcsh:QR1-502 ,antioxidant activity ,01 natural sciences ,Biochemistry ,lcsh:Microbiology ,chemistry.chemical_compound ,Autre ,Food science ,Biorefining ,Lebanon ,2. Zero hunger ,biology ,genotypic diversity ,Essential oils ,Cuminum cyminum - Genotypic diversity - Vegetable oil ,04 agricultural and veterinary sciences ,sustainability ,040401 food science ,Cuminum cyminum ,Phylogeography ,By‐products - Antimicrobial activity ,Phytochemical ,Sustainability ,vegetable oil ,Seeds ,France ,Nutritive Value ,Article ,0404 agricultural biotechnology ,Antioxidant activity ,Oils, Volatile ,Plant Oils ,[CHIM]Chemical Sciences ,Sugar ,Molecular Biology ,essential oils ,by-products ,Apiaceae ,antimicrobial activity ,Syria ,Plant Extracts ,Biorefinery ,biology.organism_classification ,Phytopathologie et phytopharmacie ,Oleic acid ,Vegetable oil ,chemistry ,Algeria ,010606 plant biology & botany - Abstract
A new biorefinery approach has been developed in the present study, and applied on cumin (Cuminum cyminum) seeds as a potential source of phytochemicals of interest. Cumin is a popular spice used widely for its distinctive aroma. It is a rich reserve of both vegetable and essential oils. The biorefinery approach here focused on the evaluation of the influence of four different geographical origins (i.e., Lebanon, France, Algeria and Syria) on oil yield and quality in cumin seed, and on the valorization of remaining by-products by investigating their nutritional content and biological activity for the first time. Vegetable and essential oils were extracted, and their compositions were determined. Nutritional traits were also assessed. The delipidated and hydrodistillated cakes just as aromatic water were characterized for their fiber, sugar, protein, phenol and flavonoid contents. Antibacterial and antioxidant activities were also determined. Cumin seeds showed high contents in both vegetable and essential oils, proteins and sugars regardless their origin. Moreover, this Apiaceae species exhibited high levels of petroselinic fatty acid (an isomer of oleic acid) and sterols. Cakes and aromatic water also presented high levels of proteins, fibers, sugars and phenols. These residues revealed interesting antioxidant and antibacterial activities. These results emphasized the potential use of cumin in a biorefinery concept, with a multi-purpose industrial process. In addition, large differences were observed between the four geographical origins for phytochemical contents and compositions. These findings highlight the perspectives for developing selection programs for nutritional traits and industrial interests. All obtained results validate the health promoting effect of cumin composition as well as its industrial importance along with the residues.
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- 2020
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5. Effect of adding a woven glass ply at the exit of the hole of CFRP laminates on delamination during drilling
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Yann Landon, P. Moussa, Pierre Rahme, Frédéric Lachaud, Centre National de la Recherche Scientifique - CNRS (FRANCE), Ecole nationale supérieure des Mines d'Albi-Carmaux - IMT Mines Albi (FRANCE), Institut National des Sciences Appliquées de Toulouse - INSA (FRANCE), Institut Supérieur de l'Aéronautique et de l'Espace - ISAE-SUPAERO (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Département de Mécanique des Structures et Matériaux - DMSM (Toulouse, France), Lebanese University [Beirut] (LU), Institut Clément Ader (ICA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
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Materials science ,Composite number ,Drilling ,Thrust ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Ply of glass/epoxy ,Pilot hole ,Critical thrust force ,Composite material ,Delamination ,Epoxy ,Composite materials ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Mécanique des structures ,Mechanics of Materials ,[SPI.MECA.STRU]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Structural mechanics [physics.class-ph] ,visual_art ,Ceramics and Composites ,visual_art.visual_art_medium ,0210 nano-technology - Abstract
International audience; Composite materials are increasingly used in the aeronautical field. The assembly of structures requires usually drilling of composite parts. Drilling of composite materials generates defects, mainly delamination at the exit of the hole. This major defect diminishes the structure strength. Delamination is directly related to the drilling thrust force. Minimizing this force reduces the defects. Adding a woven glass ply at the exit of the hole is found to be another adequate solution to reduce the defects. In this paper, the drilling of carbon/epoxy thick composite structures with a woven glass ply at the exit of the hole is considered. An analytical model is developed to determine for a given tool geometry the critical delamination forces as function of the number of non-drilled plies remaining beneath the tool. The results are validated experimentally. These results show that adding a woven glass ply at the exit of the hole reduces delamination.
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- 2020
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6. Whole-genome characterisation of TEM-1 and CMY-2 β-lactamase-producing Salmonella Kentucky ST198 in Lebanese broiler chain
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Youssef El Rayess, Sara Petrin, Rima El Hage, Alessandra Longo, Florence Mathieu, Ziad Abi Khattar, Carmen Losasso, Antonia Ricci, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Istituto Zooprofilattico Sperimentale delle Venezie (ITALY), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Holy Spirit University of Kaslik - USEK (LEBANON), Lebanese Agricultural Research Institute - LARI (LEBANON), Laboratoire de Génie Chimique - LGC (Toulouse, France), Lebanese Agricultural Research Institute (LARI), Bekaa, Lebanon, Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe), Lebanese University [Beirut] (LU), and Holy-Spirit University of Kaslik [Jounieh]
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0301 basic medicine ,Microbiology (medical) ,clone (Java method) ,Salmonella ,030106 microbiology ,Immunology ,Kentucky ,Virulence ,Microbial Sensitivity Tests ,medicine.disease_cause ,Microbiology ,beta-Lactamases ,Poultry ,03 medical and health sciences ,0302 clinical medicine ,Plasmid ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Ciprofloxacin-resistant Salmonella Kentucky ST198 ,Drug Resistance, Multiple, Bacterial ,Genomic island ,medicine ,Animals ,Immunology and Allergy ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,030212 general & internal medicine ,Insertion sequence ,Lebanon ,Génie des procédés ,Genetics ,biology ,Salmonella enterica ,ISEcp1 ,biology.organism_classification ,Pathogenicity island ,QR1-502 ,IS10 transposition ,blaCMY-2 ,Chickens ,Plasmids - Abstract
International audience; Objectives : Salmonella enterica subsp. enterica serovar Kentucky has been associated with the worldwide ciprofloxacin-resistant (CIPR) Salmonella Kentucky sequence type 198 (ST198) epidemic clone, mostly recovered from poultry farms and products. The aim of this study was to examine whether this expanding clone exists in the Lebanese broiler chain.Methods : Eight CIPR and extended-spectrum cephalosporin-resistant Salmonella Kentucky isolates previously recovered from Lebanese broilers were genetically characterised by whole-genome sequencing.Results : Seven of the eight isolates belonged to ST198 and were phylogenetically closely related. They all harboured mutations in the chromosomal quinolone resistance genesgyrA and parC with double and single substitutions, respectively. The blaTEM-1B and blaCMY-2 genes were both detected in six isolates. Insertion sequence ISEcp1 was located upstream of blaCMY-2, harboured by IncI1 plasmids in four strains. An IS10 transposition coupled to homologous recombination at transposition sites mediated CMY-2 plasmid integration into the chromosome of one strain. Resistance genes to aminoglycosides [aadA7 and aac(3)-Id], tetracyclines [tet(A)] and sulfonamides (sul1) were detected in five strains, among which four were positive for the presence of Salmonella genomic island 1 (SGI1) variant SGI1-K. All studied isolates harboured a variety of Salmonella pathogenicity islands (SPIs) as well as common regulatory and virulence genes.Conclusion : Here we report for the first time in Lebanon the detection and dissemination of the emerging highly drug-resistantSalmonella Kentucky ST198. Our findings shed new light on this clone as a potential public-health threat.
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- 2020
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7. High-frequency monitoring of surface water quality at the outlet of the Ibrahim River (Lebanon): A multivariate assessment
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Amine Kassouf, Naim Ouaini, Anne Probst, Desiree El Azzi, Jean-Luc Probst, Paula El Najjar, Claude Daou, Holy Spirit University of Kaslik (USEK), LARIFA - Faculty of Sciences Libanese University Lebanon, Laboratoire Ecologie Fonctionnelle et Environnement (LEFE), Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Holy-Spirit University of Kaslik [Jounieh], Institut de Recherches Agronomiques au Liban (IRAL), Institut de Recherches Agronomiques au Liban, Laboratoire Ecologie Fonctionnelle et Environnement (ECOLAB), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Holy Spirit University of Kaslik - USEK (LEBANON), Laboratoire Ecologie fonctionnelle et Environnement - EcoLab (Toulouse, France), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université Fédérale Toulouse Midi-Pyrénées-Institut Ecologie et Environnement (INEE)
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0106 biological sciences ,Biochemical oxygen demand ,Surface water monitoring ,[SDE.MCG]Environmental Sciences/Global Changes ,General Decision Sciences ,010501 environmental sciences ,[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil study ,010603 evolutionary biology ,01 natural sciences ,[SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems ,Dissolved organic carbon ,Lebanon ,[SDU.STU.HY]Sciences of the Universe [physics]/Earth Sciences/Hydrology ,[SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment ,Ecology, Evolution, Behavior and Systematics ,ComputingMilieux_MISCELLANEOUS ,0105 earth and related environmental sciences ,Total suspended solids ,Ecologie, Environnement ,[SDV.EE]Life Sciences [q-bio]/Ecology, environment ,Suspended solids ,Principal Component Analysis ,Ecology ,[SDE.IE]Environmental Sciences/Environmental Engineering ,Chemical oxygen demand ,Total dissolved solids ,6. Clean water ,Parameters’ reduction ,Water quality index ,13. Climate action ,Environmental chemistry ,Environmental science ,Water quality ,[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,Surface water - Abstract
International audience; Surface water quality monitoring is essential to evaluate the quality of a water resource. The current studyassesses the quality of the Ibrahim River, one of the main Lebanese rivers, exposed to considerable humanactivities. 285 samples were collected at the outlet of the river, between May 2016 and July 2017, covering onehydrological year. Twenty-three physico-chemical parameters (flow, pH, temperature, electrical conductivity,turbidity, total suspended solids, total dissolved solids, dissolved oxygen, dissolved organic carbon, biochemicaloxygen demand, chemical oxygen demand, chemical oxygen demand/biochemical oxygen demand, specificultraviolet absorbance, dissolved cations (Na+, K+, Ca2+, Mg2+), total alkalinity, dissolved anions (Cl−, NO3−,NO2−, PO43− and SO42−)) and five microbiological tests were assessed (total germs, total coliforms, fecal coliforms,Escherichia coli and Enterococcus). A Principal Component Analysis (PCA) was applied for data analysis.The first component showed high levels of anthropogenic characteristics mainly due to organic and bacteriologicalparameters, differentiating low and high river discharges (explaining around 35% of the total variance).The second component was mainly influenced by mineral variables showing a clear annual discrimination(explaining about 17% of the total variance). Moreover, this study led to variables reduction fromtwenty-eight to ten. The final shortlisted parameters are Q, pH, EC, NO3−, total coliforms, fecal coliforms, BOD5,K+, TA and Cl−. A new PCA performed with the reduced matrix validated this selection. The water quality index(WQI) was then calculated in this study, using the shortlisted parameters characterizing the basin, excluding theflow since it cannot be considered as a quality indicator. Thus, the water was evaluated as « medium » to « good »with values ranging from 63.1 (August 2016) to 73.1 (November and December 2016) with an average of69.0 ± 1.9. The proposed WQI should be further tested for monitoring practices in the Ibrahim River basin orother similar basins of the region.
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- 2019
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8. Temporal relation algebra for audiovisual content analysis
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Zein Al Abidin Ibrahim, Philippe Joly, Isabelle Ferrané, Lebanese University [Beirut] (LU), Équipe Structuration, Analyse et MOdélisation de documents Vidéo et Audio (IRIT-SAMoVA), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Institut de Recherche en Informatique de Toulouse - IRIT (Toulouse, France), and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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Structuring ,Relation (database) ,Computer Networks and Communications ,Computer science ,Audiovisual document analysis ,Context (language use) ,02 engineering and technology ,computer.software_genre ,Set (abstract data type) ,Traitement des images ,0202 electrical engineering, electronic engineering, information engineering ,Media Technology ,Logical matrix ,Representation (mathematics) ,Event (probability theory) ,Structure (mathematical logic) ,business.industry ,Temporal relations algebra ,020206 networking & telecommunications ,Relation algebra ,Classification ,Representation ,Hardware and Architecture ,[INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV] ,020201 artificial intelligence & image processing ,Artificial intelligence ,Event detection ,business ,computer ,Software ,Natural language processing - Abstract
International audience; The context of this work is to characterize the content and the structure of audiovisual documents by analysing the temporal relationships between basic events resulted from different segmentations of the same document. For this objective, we need to represent and reason about time. We propose a parametric representation of temporal relation between segments (points or intervals) in which the parameters are used to characterize the relationship between two non-convex intervals corresponding to two segmentations in the video analysis domain. The relationship is represented by a co-occurrences matrix noted as Temporal Relation Matrix (TRM). Each document is represented by a set of TRMs computed between each couple of segmentations of the same document using different features. The TRMs are analysed later to detect semantic events, highlight clues about the video content structure or to classify documents based on their types. For higher-level semantic events and documents’ structure, we needed to apply some operations on the basic temporal relations and TRMs such as composition, disjunction, complement, intersection, etc. These operations brought to light more complex patterns; e.g. event 1 occurs at the same time of event 2 followed by event 3. In the work presented in this paper, we define a temporal relation algebra including its set of operations based on the parametric representation and TRM defined above. Several experimentations have been done on different audio and video documents to show the efficiency of the proposed representation and the defined operations for audiovisual content analysing.
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- 2018
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9. Supercritical carbon dioxide extraction and fractionation of lipids from freeze-dried microalgae Nannochloropsis oculata and Chlorella vulgaris
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Nicholas Beaufils, Pierre-Yves Pontalier, Ali Ismail, Sara Obeid, Hosni Takache, Séverine Camy, Chimie Agro-Industrielle (CAI), Institut National de la Recherche Agronomique (INRA)-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Institut National de la Recherche Agronomique - INRA (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Laboratoire de Génie Chimique - LGC (Toulouse, France), Laboratoire de Chimie Agro-Industrielle (LCA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure de Chimie de Toulouse, Lebanese University [Beirut], and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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020209 energy ,Chlorella vulgaris ,Supercritical carbon dioxide extraction ,02 engineering and technology ,Fractionation ,010501 environmental sciences ,01 natural sciences ,chemistry.chemical_compound ,Glycolipid ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Nannochloropsis oculata ,0202 electrical engineering, electronic engineering, information engineering ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Solid phase extraction ,Génie des procédés ,0105 earth and related environmental sciences ,Supercritical carbon dioxide ,Chromatography ,Ethanol ,Chemistry ,Extraction (chemistry) ,Yield (chemistry) ,lipids (amino acids, peptides, and proteins) ,Agronomy and Crop Science ,Neutral lipids - Abstract
International audience; This study deals with the selective extraction of neutral lipids from microalgae. We investigated the consequences of bypassing cell-wall disintegration before supercritical carbon dioxide extraction. Different operating parameters (use of co-solvent, pressure, and time) were tested on freeze-dried Chlorella vulgaris and Nannochloropsis oculata. The solid phase extraction technique (SPE) was used throughout the extraction process to assess variations in the yield of liberated neutral lipids, glycolipids, and phospholipids. Under operating conditions, 97% of neutral lipids were extracted from C. vulgaris using ethanol (10% v/v) as co-solvent. Neutral lipids from N. oculata represented most of the extracts (83%), whereas the proportion of glycolipids and phospholipids did not exceed 12.1% and 5.3%, respectively. Microscopic observation showed that cell wall integrity was maintained during the extraction process.
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- 2018
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10. Identification of multiple-derived peptides produced by Saccharomyces cerevisiae involved in malolactic fermentation inhibition
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Nancy Nehme, Ziad Rizk, Florence Mathieu, Patricia Taillandier, Chantal Ghanem, Youssef El Rayess, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Holy Spirit University of Kaslik - USEK (LEBANON), Lebanese Agricultural Research Institute - LARI (LEBANON), Laboratoire de Génie Chimique - LGC (Toulouse, France), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese Agricultural Research Institute (LARI), Holy-Spirit University of Kaslik [Jounieh], Laboratoire de Génie Chimique (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, and Lebanese University [Beirut] (LU)
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0301 basic medicine ,[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,Saccharomyces cerevisiae ,Malates ,Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) ,Wtm2p ,Applied Microbiology and Biotechnology ,Microbiology ,Malolactic fermentation (MLF) ,Anti-MLF yeast peptides ,Fungal Proteins ,03 medical and health sciences ,chemistry.chemical_compound ,Malate Dehydrogenase ,Malolactic fermentation ,Génie chimique ,Vitis ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Amino Acid Sequence ,Lactic Acid ,Génie des procédés ,Oenococcus ,Ammonium sulfate precipitation ,Tricine ,biology ,Malolactic enzyme activity ,General Medicine ,Hydrogen-Ion Concentration ,biology.organism_classification ,Yeast ,Enzyme assay ,Molecular Weight ,030104 developmental biology ,chemistry ,Biochemistry ,Fermentation ,biology.protein ,Utr2p ,Peptides - Abstract
International audience; An oenological strain of Saccharomyces cerevisiae was previously shown to produce a 5–10 kDa peptidic fraction responsible for the inhibition of malolactic fermentation (MLF). In the present study, we aim to further purify the anti-MLF peptides of this fraction. The yeast fermented synthetic grape juice medium was fractionated by ammonium sulfate precipitation combined with ultrafiltration. The 5–10 kDa fraction recovered at a saturation degree of 60%–80% was the only fraction that inhibited both the bacterial growth and the malate consumption in vivo. It also inhibited the malolactic enzyme activity in vitro at a pH range between 3.5 and 6.7. Therefore, it was purified by both anion and cation exchange chromatography. The eluates that inhibited the malolactic enzyme activity in vitro were migrated on Tricine SDS-PAGE and the protein bands were excised and sequenced by LC-MS/MS. The sequencing revealed nine peptides originating from eight proteins of S. cerevisiae. Two GAPDH cationic fragments of 0.9 and 1.373 kDa having a pI of 10.5 and 11 respectively, Wtm2p and Utr2p anionic fragments of 2.42 kDa with a pI of 3.5 and 4 respectively were thought to contribute the most to the MLF inhibition
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- 2018
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11. Classifying Deformable and Non-deformable Video Objects
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Siba Haidar, Philippe Joly, Wael F. Youssef, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), and Université Toulouse 1 Capitole - UT1 (FRANCE)
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Video database indexing ,Computer science ,business.industry ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Video analysis ,Motion classification ,Temporal consistency ,Traitement des images ,Fully automated ,Object classification ,Computer vision ,Artificial intelligence ,business ,Fundamental matrix (computer vision) ,Fundamental matrix ,ComputingMethodologies_COMPUTERGRAPHICS - Abstract
This paper presents a fully automated approach to classifying deformable and non-deformable moving objects in a video surveillance scene. We estimate an object's motion using Marzat optical-flow algorithm. We filter the motion vectors and attempt to find the transformation that represents the correct mapping between the two positions. The Fundamental transformation is estimated using the Normalized Eight-Point Algorithm. We introduce a new type of graph to set the thresholds between deformable and non-deformable motion. Furthermore, we use temporal consistency to classify deformable and non-deformable objects. For experiments, we used a varied corpus of real surveillance videos. Our proposed approach for motion classification achieved a precision rate of 92 percent.
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- 2018
12. Fennel oil and by-products seed characterization and their potential applications
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Zeinab Saad, Thierry Talou, Muriel Cerny, Akram Hijazi, Hussein Kanaan, Ali Chokr, Bouchra Sayed Ahmad, Othmane Merah, Laboratoire de Chimie Agro-Industrielle (LCA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure de Chimie de Toulouse, Lebanese University [Beirut], Pathogenèse des légionelles- Legionella pathogenesis, Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Chimie Agro-Industrielle (CAI), Institut National de la Recherche Agronomique (INRA)-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques (ENSIACET), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT), Lebanese University [Beirut] (LU), Pathogenèse des légionelles- Legionella pathogenesis (LegioPath), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National de la Recherche Agronomique (INRA), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut National Polytechnique de Toulouse - INPT (FRANCE), Institut National de la Recherche Agronomique - INRA (FRANCE), Lebanese University - LU (LEBANON), Laboratory of Microbiology (Beirut, Lebanon), and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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Foeniculum ,Bio-refining concept ,Biomass ,[CHIM.THER]Chemical Sciences/Medicinal Chemistry ,01 natural sciences ,12. Responsible consumption ,law.invention ,chemistry.chemical_compound ,0404 agricultural biotechnology ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Antioxidant activity ,law ,Food science ,Fennel Oil ,Moisturizing cream ,Essential oil ,2. Zero hunger ,Petroselinic acid ,biology ,Chemistry ,business.industry ,010401 analytical chemistry ,Extraction (chemistry) ,04 agricultural and veterinary sciences ,biology.organism_classification ,040401 food science ,0104 chemical sciences ,Biotechnology ,Vegetable oil ,Residual by-products ,business ,Fennel seeds ,Agronomy and Crop Science ,Sciences agricoles ,Renewable resource - Abstract
International audience; The implementation of renewable resources in the industrial production processes appears to be the most effective way to achieve sustainable development. However, in order to tackle the key issues of shifting to renewable resources, a full exploitation of biomass resources and efficient utilization of complex organic macromolecules and also other chemical constituents such as antioxidants in bio-refinery system will be crucial. In this regard, fennel (Foeniculum vulgare) seeds could be a promising bio-resource with significant interest as a rich source of both vegetable oil (VO) and essential oil (EO), in addition to rare phytochemicals. Thus, in the present paper, a trans-disciplinary assessment of a new bio-refinery process from fennel seeds was established: the development of an integrated valorization of fennel seeds, allowing the extraction of VO and EO and their exploitation in cosmetic applications as well as the valorization of residual by-products as a source of biologically active compounds, these processes constituted the basis of this bio-refinery concept. Laboratory obtained results and pilot-scale levels with fennel seeds reported extraction of high yield of both VO and EO (19.8% and 1.8%, respectively) with significant amounts of valuable components, petroselinic acid and trans-anethole (74.8% and 70.7%, respectively). Further, the valorization of these oils as functional ingredients in moisturizing cream formulas showed a positive impact on the overall emulsions structure and quality. Next to this, fennel oilseeds by-products exhibited a remarkable antioxidant potential with high phenols and flavonoids contents and exhibited good antimicrobial properties depending on the extract type. These promising findings are of great economic interest as they can lead to a wild range of novel, bio-based industrial applications from fennel seeds.
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- 2018
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13. Evaluation of Nutritional and Technological Attributes of Whole Wheat Based Bread Fortified with Chia Flour
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Martins Sabovics, Zanda Kruma, Othmane Merah, Akram Hijazi, Thierry Talou, Evita Straumite, Zeinab Saad, Bouchra Sayed-Ahmad, Laboratoire de Chimie Agro-Industrielle (LCA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure de Chimie de Toulouse, Lebanese University [Beirut], University of Latvia (LU), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut National de la Recherche Agronomique - INRA (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), University of Latvia (LATVIA), Chimie Agro-Industrielle (CAI), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National de la Recherche Agronomique (INRA), Lebanese University [Beirut] (LU), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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Health (social science) ,Fortification ,Ingénierie des aliments ,Wheat gluten ,Whole wheat bread ,Plant Science ,Sensory profile ,lcsh:Chemical technology ,Health Professions (miscellaneous) ,Microbiology ,Article ,Chia cake ,0404 agricultural biotechnology ,Antioxidant activity ,[SDV.IDA]Life Sciences [q-bio]/Food engineering ,lcsh:TP1-1185 ,Food science ,Bread making ,Mathematics ,2. Zero hunger ,Nutritional content ,digestive, oral, and skin physiology ,food and beverages ,Chia seed ,04 agricultural and veterinary sciences ,Wheat bread ,Whole wheat ,040401 food science ,Bread quality ,Food Science - Abstract
International audience; The aim of this study was to investigate and compare the effect of wheat bread fortification with varied levels (2%, 4%, and 6%) of chia seed powder (full fat) and cakes (defatted, residue after oil extraction). Chia flour was added to whole wheat bread rich in vital wheat gluten for the first time. The breadcrumbs were assessed for their antioxidant activity, nutritional content, textural properties, color, and sensory profiles. The addition of chia seed powder, particularly in high levels, was more effective in improving antioxidant activity compared to bread fortified with chia cakes. Bread supplementation with chia flour improves its nutritional value, especially in the case of chia cakes. A higher moisture content and lower hardness were observed after bread fortification, the influence was more evident with the defatted cake than with seed powder. Fortification with chia flour led to darker breads without significantly affecting their global acceptability. However, the fortified bread showed better values than control in terms of sensory profile. These results suggest that the addition of chia seed powder and defatted cake can enhance the overall whole wheat bread quality. Our results also highlight that bread making could be an unconventional alternative for the exploitation of defatted chia seed.
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- 2018
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14. Protein Bread Fortification with Cumin and Caraway Seeds and By-Product Flour
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Zanda Kruma, Zeinab Saad, Bouchra Sayed Ahmad, Othmane Merah, Akram Hijazi, Evita Straumite, Martins Sabovics, Thierry Talou, Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut National de la Recherche Agronomique - INRA (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), University of Latvia (LATVIA), Institut National Polytechnique de Toulouse - INPT (FRANCE), Chimie Agro-Industrielle (CAI), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National de la Recherche Agronomique (INRA), University of Latvia (LU), Lebanese University [Beirut] (LU), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Merah, Othmane, Laboratoire de Chimie Agro-Industrielle (LCA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure de Chimie de Toulouse, and Lebanese University [Beirut]
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0301 basic medicine ,Cuminum ,Health (social science) ,Cumin ,caraway ,cumin ,bread quality ,by-products ,radical scavenging activity ,total phenolic ,Fortification ,By-products ,Plant Science ,Antioxidant potential ,lcsh:Chemical technology ,Health Professions (miscellaneous) ,Microbiology ,Article ,Radical scavenging activity ,03 medical and health sciences ,0404 agricultural biotechnology ,By-product ,lcsh:TP1-1185 ,Food science ,Developing regions ,Mathematics ,2. Zero hunger ,030109 nutrition & dietetics ,Total phenolic ,biology ,digestive, oral, and skin physiology ,food and beverages ,04 agricultural and veterinary sciences ,biology.organism_classification ,040401 food science ,Bread quality ,Food waste ,Carum carvi ,Alimentation et Nutrition ,Caraway ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Food Science - Abstract
International audience; Malnutrition continues to be a key health problem in developing regions. The valorization of food waste appears as an ideal way to prevent malnutrition and improve people’s access to food. Cumin (Cuminum cyminum L.) and caraway (Carum carvi L.) oilseeds are commonly used for cuisine and medicinal purposes. However, remaining cakes after oil extraction are usually underutilized. In order to assess the usefulness of these by-products in food applications, this study investigated the effect of their addition to protein bread formulations. Different levels (2, 4 and 6%) of whole seeds and cakes flour were used in the study. Fortified protein bread samples were compared to control protein bread and evaluated for their sensory, color, moisture, hardness properties, nutritional values as well as their biological activity. Results indicated that bread fortification shows a significant effect on bread properties depending on fortification level. A higher acceptability was observed specially for bread fortified with by-products flour. Increased tendencies of color darkness, moisture content, bread hardness, nutritional values as well as total phenolic content and radical scavenging activity compared to control bread were observed as the percentage of fortification increased in both cases. The overall results showed that the addition of cumin and caraway seeds and by-product flour can improve the antioxidant potential and overall quality of protein bread.
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- 2018
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15. Dental root canal segmentation from super-resolved 3D cone beam computed tomography data
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Adrian Basarab, Jerome Michetti, Rose Sfeir, Frank Diemer, Bilal Chebaro, Denis Kouame, Centre National de la Recherche Scientifique - CNRS (FRANCE), Ecole nationale supérieure des Mines d'Albi-Carmaux - IMT Mines Albi (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut National des Sciences Appliquées de Toulouse - INSA (FRANCE), Institut Supérieur de l'Aéronautique et de l'Espace - ISAE-SUPAERO (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Faculté de Chirurgie Dentaire (Toulouse, France), Traitement et Compréhension d’Images (IRIT-TCI), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), Faculté de chirurgie dentaire, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut Clément Ader (ICA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), CoMputational imagINg anD viSion (IRIT-MINDS), Université de Toulouse (UT)-Université de Toulouse (UT), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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Inverse problems ,medicine.medical_specialty ,Cone beam computed tomography ,Endodontics -Image segmentation ,Computer science ,Root canal ,Micro computed tomography ,Image processing ,02 engineering and technology ,urologic and male genital diseases ,03 medical and health sciences ,0302 clinical medicine ,stomatognathic system ,[INFO.INFO-IM]Computer Science [cs]/Medical Imaging ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Segmentation ,Image resolution ,Imagerie médicale ,030206 dentistry ,Image segmentation ,respiratory system ,Endodontics ,equipment and supplies ,Superresolution ,medicine.anatomical_structure ,Super-resolution ,020201 artificial intelligence & image processing ,Biomedical engineering - Abstract
National audience; This paper aims at evaluating the potential of super-resolution (SR) image processing to enhance the resolution of Cone Beam Computed Tomography (CBCT) images and to further improve the root canal segmentation in endodontics. First we perform SR based on a linear model, then, we apply an automated segmentation procedure to native and super-resolved CBCT volumes in order to extract the root canal structure. Seven intact extracted teeth have been used to evaluate the potential of SR CBCT in detecting the dental root canal. For all the considered teeth, the SR CBCT volumes provided a smaller error compared to the native CBCT data.
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- 2017
16. Analysis of the impact of fining agents types, oenological tannins and mannoproteins and their concentrations on the phenolic composition of red wine
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M. Rizk, Jean-Pierre Souchard, Nancy Nehme, Ziad Rizk, Y. El Rayess, Chantal Ghanem, Patricia Taillandier, Holy-Spirit University of Kaslik [Jounieh], Lebanese Agricultural Research Institute (LARI), Laboratoire de Génie Chimique (LGC), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Lebanese University [Beirut] (LU), Interactions moléculaires et réactivité chimique et photochimique (IMRCP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Fluides, Energie, Réacteurs, Matériaux et Transferts (FERMAT), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), IDeAS - Interfaces Dynamiques et Assemblages Stimulables (IDeAS), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie de Toulouse (ICT), Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Holy Spirit University of Kaslik - USEK (LEBANON), Lebanese Agricultural Research Institute - LARI (LEBANON), Laboratoire de Génie Chimique - LGC (Toulouse, France), Laboratoire des Interactions Moléculaires et de la Réactivité Chimique et Photochimique – IMRCP (Toulouse, France), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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Antioxidant ,Polyvinylpolypyrrolidone ,food.ingredient ,medicine.medical_treatment ,01 natural sciences ,Gelatin ,Anthocyanins ,chemistry.chemical_compound ,Pigment ,0404 agricultural biotechnology ,food ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Antioxidant activity ,medicine ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Food science ,Génie des procédés ,Mannoproteins ,Wine ,Chromatography ,010401 analytical chemistry ,food and beverages ,04 agricultural and veterinary sciences ,040401 food science ,0104 chemical sciences ,Fining agents ,chemistry ,Polyphenol ,visual_art ,Bentonite ,visual_art.visual_art_medium ,Composition (visual arts) ,Tannins ,Food Science - Abstract
International audience; This paper aimed to evaluate and analyze the effect of five fining agents, commercial tannins and mannoproteins on the pigment, color and tannins composition of a Cabernet Sauvignon red wine. The wines were analyzed 2 d after treatment and immediately after separation of sedimentation. Color was evaluated by spectrophotometry and polyphenols were analyzed by spectrophotometry and HPLC-DAD. The results showed that all treatments affected the phenolic contents of the wine. The most remarkable effects on phenolic composition were produced by bentonite and Polyvinylpolypyrrolidone (PvPP) + potassium caseinate which significantly decreased anthocyanins and tannins concentrations, respectively. The use of vegetable protein and gelatin has a less impact on the color and phenolic contents of red wines. The antioxidant activity was little affected by treatments except the addition of tannins that increased it. Principal components analysis demonstrates the importance of a low concentration of agents for high total polyphenol levels.
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- 2017
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17. Modelling Strategies for Predicting the Residual Strength of Impacted Composite Aircraft Fuselages
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Robert Piquet, Pierre Rahme, Laurent Michel, Frédéric Lachaud, Christine Espinosa, Institut Clément Ader (ICA), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO), Notre Dame University-Louaize [Lebanon] (NDU), Centre National de la Recherche Scientifique - CNRS (FRANCE), Ecole nationale supérieure des Mines d'Albi-Carmaux - IMT Mines Albi (FRANCE), Institut National des Sciences Appliquées de Toulouse - INSA (FRANCE), Institut Supérieur de l'Aéronautique et de l'Espace - ISAE-SUPAERO (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Département de Mécanique des Structures et Matériaux - DMSM (Toulouse, France), Institut Supérieur de l'Aéronautique et de l'Espace (ISAE-SUPAERO)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-IMT École nationale supérieure des Mines d'Albi-Carmaux (IMT Mines Albi), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
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Smooth Particle Hydrodynamics ,Materials science ,Compression After Impact ,02 engineering and technology ,Smoothed-particle hydrodynamics ,0203 mechanical engineering ,Coupling (piping) ,Composite material ,Crack Propagation ,Mixed Mode ,business.industry ,Numerical analysis ,Delamination ,Fracture mechanics ,Structural engineering ,021001 nanoscience & nanotechnology ,Compression (physics) ,[SPI.MECA.GEME]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Mechanical engineering [physics.class-ph] ,Residual strength ,Mécanique des structures ,020303 mechanical engineering & transports ,Fuselage ,Ceramics and Composites ,Composite Materials ,0210 nano-technology ,business ,CompositeMaterials - Abstract
International audience; Aeronautic Certification rules established for the metallic materials are not convenient for the composite structures concerning the resistance against impact. The computer-based design is a new methodology that is thought about to replace the experimental tests. It becomes necessary for numerical methods to be robust and predictive for impact. Three questions are addressed in this study: (i) can a numerical model be \textquotedblleftmechanically intrinsic\textquotedblright to predict damage after impact, (ii) can this model be the same for a lab sample and a large structure, and (iii) can the numerical model be predictive enough to predict the Compression After Impact (CAI)? Three different computational strategies are used and compared: a Cohesive Model (CM), a Continuous Damage Model (CDM) coupling failure modes and damage, and a Mixed Methodology (MM) using the CDM for delamination initiation and the CM for cracks propagation. The first attempts to use the Smooth Particle Hydrodynamics method are presented. Finally, impact on a fuselage is modelled and a numerical two-stage strategy is developed to predict the CAI.
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- 2014
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18. Effect of Addition of Fennel (Foeniculum vulgare L.) on the Quality of Protein Bread
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Evita Straumīte, Bouchra Sayed-Ahmad, Akram Hijazi, Zanda Krūma, Zeinab Saad, Othmane Merah, Mārtiņš Šabovics, Thierry Talou, Laboratoire de Chimie Agro-Industrielle (LCA), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Supérieure de Chimie de Toulouse, Lebanese University [Beirut], University of Latvia (LU), Chimie Agro-Industrielle (CAI), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National de la Recherche Agronomique (INRA), Lebanese University [Beirut] (LU), Institut National Polytechnique de Toulouse - INPT (FRANCE), Institut National de la Recherche Agronomique - INRA (FRANCE), Lebanese University - LU (LEBANON), University of Latvia (LATVIA), Sayed Ahmad, Bouchra, and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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0301 basic medicine ,Antioxidant ,Fennel ,Foeniculum ,DPPH ,Science ,medicine.medical_treatment ,Radical scavenging activity ,03 medical and health sciences ,chemistry.chemical_compound ,0404 agricultural biotechnology ,medicine ,[SDV.BV]Life Sciences [q-bio]/Vegetal Biology ,Food science ,Fennel cake ,Bread making ,2. Zero hunger ,030109 nutrition & dietetics ,Multidisciplinary ,Apiaceae ,fennel ,fennel cake ,bread quality ,total phenolic ,radical scavenging activity ,Total phenolic ,Moisture ,biology ,Chemistry ,Extraction (chemistry) ,digestive, oral, and skin physiology ,food and beverages ,04 agricultural and veterinary sciences ,biology.organism_classification ,040401 food science ,Bread quality ,Fennel seeds ,Biologie végétale - Abstract
Fennel (Foeniculum vulgare L.) is an aromatic plant belonging to Apiaceae family widely cultivated elsewhere for its strongly flavoured leaves and seeds. Fennel seeds are of particular interest as a rich source of both vegetable and essential oils with high amounts of valuable components. However, residual cakes after oil extraction were typically considered as byproducts, in the present framework, the potential added value of these cakes was studied. The aim of this study was to investigate the effect of addition of fennel cake and seeds to protein bread quality. In the current research, a single-screw extruder, which is a solvent-free technique, was used for fennel seed oil extraction. For the protein bread making, fennel seed and cake flour in concentrations from 1 to 6% were used. Moisture, colour L*a*b*, hardness, total phenolic concentration, DPPH radical scavenging activity, and nutritional value of protein bread were determined. The addition of fennel cake and seeds had significant (p < 0.05) effect on bread crumb colour and hardness attribute, whereby the bread became darker and harder in texture than the control. Moreover, higher antioxidant activity and total phenolic concentration were observed for both protein breads enriched with fennel cake and seed flour. The overall results showed that addition of fennel cake and seed had beneficial effects on phenolic concentration, antioxidant activity and quality of protein bread. This result suggests also that added value of fennel seeds oil by-products could be increased by their utilisation in bread production.
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- 2017
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19. Ability of Soil Isolated Actinobacterial Strains to Prevent, Bind and Biodegrade Ochratoxin A
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Richard G. Maroun, Charbel Afif, Rachelle El Khoury, Anthony El Khoury, Ali Atoui, Hiba Kawtharani, Florence Mathieu, André El Khoury, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Saint-Joseph de Beyrouth - USJ (LEBANON), Institut National Polytechnique de Toulouse - INPT (FRANCE), Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Université Saint-Joseph de Beyrouth (USJ), and Lebanese University [Beirut] (LU)
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0301 basic medicine ,Ochratoxin A ,[SDV.BIO]Life Sciences [q-bio]/Biotechnology ,binding ,Health, Toxicology and Mutagenesis ,Genes, Fungal ,030106 microbiology ,lcsh:Medicine ,Food Contamination ,Toxicology ,Streptomyces ,Article ,Microbiology ,Actinobacteria ,03 medical and health sciences ,chemistry.chemical_compound ,Biosynthesis ,Cell Wall ,Gene Expression Regulation, Fungal ,Gene expression ,Génie chimique ,biocontrol ,Genes expression ,detoxification ,Mycotoxin ,Incubation ,Soil Microbiology ,2. Zero hunger ,Génie civil ,biology ,Strain (chemistry) ,lcsh:R ,Biocontrol ,actinobacteria ,genes expression ,Binding ,biology.organism_classification ,Ochratoxins ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Aspergillus ,Biodegradation, Environmental ,chemistry ,Detoxification - Abstract
International audience; Ochratoxin A (OTA) is one of the most important mycotoxins, and contaminates several agricultural products, particularly cereals, grapes, maize, barley, spices and coffee. The aim of this project was to reduce the levels of OTA by supplementing the artificially contaminated solutions with seven strains of actinobacteria (AT10, AT8, SN7, MS1, ML5, G10 and PT1) in order to evaluate their capacity for binding and metabolizing the OTA, as well as their ability to reduce the expression of the genes responsible for its production in A. carbonarius. In the first part of this study, we evaluated the capacity of Streptomyces strains for binding OTA on their surfaces after 0, 30 and 60 min of incubation with PBS solution supplemented with OTA. In the second part, we tested the ability of these strains, as well as their supernatants, to detoxify the ISP2 medium. Finally, we studied the effect of the Streptomyces cocultured with Aspergillus carbonarius on the expression of OTA biosynthesis genes. Results showed that, among the strains co-cultured with A. carbonarius, the strain G10 was able to reduce the expression of acpks, acOTApks, acOTAnrps and vea genes, thus reducing OTA from solid PDA medium to 13.50% of reduction. This strain was remarkably able to detoxify and bind OTA up to 47.07%. Strain AT8 was stronger in detoxifying OTA (52.61%), but had no significant effect on the studied gene expression.
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- 2017
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20. Impact of inhibitory peptides released by Saccharomyces cerevisiae BDX on the malolactic fermentation performed by Oenococcus oeni Vitilactic F
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Ziad Rizk, Patricia Taillandier, Florence Mathieu, Nancy Nehme, Youssef El Rayess, Chantal Ghanem, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Holy Spirit University of Kaslik - USEK (LEBANON), Lebanese Agricultural Research Institute - LARI (LEBANON), Laboratoire de Génie Chimique - LGC (Toulouse, France), Lebanese Agricultural Research Institute (LARI), Holy-Spirit University of Kaslik [Jounieh], Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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0301 basic medicine ,Malolactic enzyme ,030106 microbiology ,Saccharomyces cerevisiae ,Malates ,Wine ,Ethanol fermentation ,Microbiology ,03 medical and health sciences ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Bacterial Proteins ,Malate Dehydrogenase ,Malolactic fermentation ,Génie chimique ,Vitis ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Génie des procédés ,Oenococcus ,Oenococcus oeni ,biology ,Chemistry ,Malolactic enzyme activity ,General Medicine ,biology.organism_classification ,Yeast ,Kinetics ,030104 developmental biology ,Biochemistry ,Antibacterial yeast peptidic compounds ,Fermentation ,Peptides ,Food Science - Abstract
International audience; A previous study has shown that the malolactic fermentation (MLF) was inhibited during sequential fermentations performed with the pair Saccharomyces cerevisiae BDX/Oenococcus oeni Vitilactic F in synthetic grape juices. A yeast peptidic fraction with an apparent MW of 5-10kDa was involved in the inhibition. In the present study, the MLF was also inhibited in Cabernet Sauvignon and Syrah wines. The inhibition due to the peptidic fraction was maintained despite high phenolic contents. Kinetic studies showed that the peptidic fraction was gradually released during the alcoholic fermentation (AF). Its highest anti-MLF effect was reached when isolated from late stages of the AF stationary phase. The peptidic fraction was tested in vitro on cell-free bacterial cytosolic extracts containing the malolactic enzyme in a pH range between 3.5 and 6.7. Results showed that it was able to directly inhibit the malolactic enzyme activity with an increasing inhibitory kinetic correlated to the AF time at which it was collected.
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- 2016
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21. Essential Oils Modulate Gene Expression and Ochratoxin A Production in Aspergillus carbonarius
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Carol Verheecke, Rachelle El Khoury, Richard G. Maroun, Florence Mathieu, Ali Atoui, André El Khoury, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Saint-Joseph de Beyrouth - USJ (LEBANON), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Faculté des Sciences, Département des sciences de la vie et de la terres - Biochimie, Laboratoire de Mycologie et Sécurité des Aliments (LMSA), Université Saint-Joseph de Beyrouth (USJ), Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université Fédérale Toulouse Midi-Pyrénées
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0301 basic medicine ,Ochratoxin A ,Health, Toxicology and Mutagenesis ,030106 microbiology ,lcsh:Medicine ,Aspergillus carbonarius ,Toxicology ,Article ,Ochratoxins ,Microbiology ,03 medical and health sciences ,chemistry.chemical_compound ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Biosynthesis ,Gene Expression Regulation, Fungal ,Gene expression ,Oils, Volatile ,Plant Oils ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Food science ,Génie des procédés ,Mycotoxin ,essential oils ,Regulator gene ,2. Zero hunger ,Aspergillus ,biology ,lcsh:R ,biology.organism_classification ,chemistry ,Essential oils ,gene expression - Abstract
International audience; Ochratoxin A (OTA) is a mycotoxin, mainly produced on grapes by Aspergillus carbonarius, that causes massive health problems for humans. This study aims to reduce the occurrence of OTA by using the ten following essential oils (E.Os): fennel, cardamom, anise, chamomile, celery, cinnamon, thyme, taramira, oregano and rosemary at 1 µL/mL and 5 µL/mL for each E.O.As a matter of fact, their effects on the OTA production and the growth of A. carbonarius S402 cultures were evaluated, after four days at 28 °C on a Synthetic Grape Medium (SGM). Results showed that A. carbonarius growth was reduced up to 100%, when cultured with the E.Os of cinnamon, taramira, and oregano at both concentrations and the thyme at 5 µL/mL. As for the other six E.Os, their effect on A. carbonarius growth was insignificant, but highly important on the OTA production. Interestingly, the fennel E.O at 5 µL/mL reduced the OTA production up to 88.9% compared to the control, with only 13.8% of fungal growth reduction. We further investigated the effect of these E.Os on the expression levels of the genes responsible for the OTA biosynthesis (acOTApks and acOTAnrps along with the acpks gene) as well as the two regulatory genes laeA and vea, using the quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) method. The results revealed that these six E.Os reduced the expression of the five studied genes, where the ackps was downregulated by 99.2% (the highest downregulation in this study) with 5 µL/mL of fennel E.O.As for the acOTApks, acOTAnrps, veA and laeA, their reduction levels ranged between 10% and 96% depending on the nature of the E.O and its concentration in the medium.
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- 2016
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22. Elaboration and characterization of barium titanate powders obtained by the mechanical activation of barium nitrate and titanate oxide, and electrical properties of the ceramics sintered by SPS
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Al-Naboulsi, Tawfik, Boulos, Madona, Tenailleau, Christophe, Dufour, Pascal, Zakhour, Mirvat, Guillemet-Fritsch, Sophie, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Laboratoire de Chimie Physique des Matériaux (LCPM), Université Libanaise, Centre interuniversitaire de recherche et d'ingenierie des matériaux (CIRIMAT), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con] ,Barium titanate ,Matériaux ,Electrical properties ,SPS ,[CHIM.MATE]Chemical Sciences/Material chemistry ,[SPI.MAT]Engineering Sciences [physics]/Materials ,Supraconductivité ,Mechanosynthesis - Abstract
International audience; The current work aims to reduce the energy required to obtain a high quality barium titanate nanocrystals via solid-state reaction. In order to achieve this challenge, Ba(NO3)2 and TiO2 were mechanically activated by high-energy ball milling, and then heat treated at moderate temperature (600 oC). When stoichiometric mixture was used, the formation of BT and minor BaCO3 and TiO2 impurities was observed. The use of Ba(NO3)2 excess leads to the formation of BT and a minor BaCO3 impurity. A simple acid wash treatment was used to remove the carbonate impurity and to provide a high purity BT. The powders were characterized by XRD, BET, Raman spectroscopy, and SEM-FEG. Spark Plasma Sintering (SPS) technique was used to get the dense nanoceramics. These materials show, at room temperature and at 1 kHz, colossal permittivity (ε = 105) associated with low dielectric loss (tg δ = 0.07).
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- 2016
23. Action boundaries detection in a video
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Bassem Haidar, Hassan Wehbe, Philippe Joly, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Équipe Structuration, Analyse et MOdélisation de documents Vidéo et Audio (IRIT-SAMoVA), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Lebanese International University (LIU), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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0209 industrial biotechnology ,Computer Networks and Communications ,Computer science ,02 engineering and technology ,Video analysis ,[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI] ,Codebook quantization ,Traitement des images ,020901 industrial engineering & automation ,Segmentation ,[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing ,0202 electrical engineering, electronic engineering, information engineering ,Media Technology ,Traitement du signal et de l'image ,Computer vision ,Action detection ,Synthèse d'image et réalité virtuelle ,Pixel ,business.industry ,Quantization (signal processing) ,Codebook ,[INFO.INFO-CV]Computer Science [cs]/Computer Vision and Pattern Recognition [cs.CV] ,Vision par ordinateur et reconnaissance de formes ,Intelligence artificielle ,[INFO.INFO-GR]Computer Science [cs]/Graphics [cs.GR] ,Hardware and Architecture ,[INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV] ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,Software - Abstract
International audience; In the video analysis domain, automatic detection of actions performed in a recorded video represents an important scientific and industrial challenge. This paper presents a new method to approximate the boundaries of actions performed by a person while interacting with his environment (such as moving objects). This method relies on a Codebook quantization method to analyze the rough evolution of each pixel and then decide whether this evolution corresponds to an action or not; this decision is taken by an automated system. Statistics are then produced - at the scale of the whole frame - to estimate the start and the end of an action. According to our proposed evaluation protocol, this method produces interesting results on both real and simulated videos. This statistic-based protocol is discussed at the end of this paper. The interpretation of this evaluation protocol nominates this method to be a solid base to localize the exact boundaries of actions or - in the framework of this research activity - to associate prescriptive text with a visual content.
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- 2015
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24. Unsupervised spectral clustering for segmentation of dynamic PET images
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Simon Stute, Irène Buvat, Sylvie Chalon, Laurent Galineau, Clovis Tauber, Jamal Charara, Hiba Zbib, Jean-Marc Girault, Sandrine Mouysset, Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Lebanese University [Beirut] (LU), Algorithmes Parallèles et Optimisation (IRIT-APO), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse Capitole (UT Capitole), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse Capitole (UT Capitole), Université Fédérale Toulouse Midi-Pyrénées, Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), (OATAO), Open Archive Toulouse Archive Ouverte, Commissariat à l'Energie Atomique et aux énergies alternatives - CEA (FRANCE), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Université de Tours (FRANCE), Institut de Recherche en Informatique de Toulouse - IRIT (Toulouse, France), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Université Libanaise, Université Toulouse 1 Capitole (UT1)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Imagerie et cerveau, Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Service Hospitalier Frédéric Joliot (SHFJ), and Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA))
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Nuclear and High Energy Physics ,Computer science ,Correlation clustering ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,02 engineering and technology ,Clustering ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Spectral clustering ,[INFO.INFO-IM]Computer Science [cs]/Medical Imaging ,0202 electrical engineering, electronic engineering, information engineering ,Segmentation ,Electrical and Electronic Engineering ,Cluster analysis ,Global optimization ,ComputingMilieux_MISCELLANEOUS ,business.industry ,Segmentation-based object categorization ,Pattern recognition ,Recherche d'information ,Image segmentation ,Weighting ,Nuclear Energy and Engineering ,[INFO.INFO-IR]Computer Science [cs]/Information Retrieval [cs.IR] ,020201 artificial intelligence & image processing ,Artificial intelligence ,Segmentation of dynamic PET image ,[INFO.INFO-IR] Computer Science [cs]/Information Retrieval [cs.IR] ,business - Abstract
International audience; Segmentation of dynamic PET images is needed to extract the time activity curves (TAC) of regions of interest (ROI). These TAC can be used in compartmental models for in vivo quantification of the radiotracer target. While unsupervised clustering methods have been proposed to segment PET sequences, they are often sensitive to initial conditions or favour convex shaped clusters. Kinetic spectral clustering (KSC) of dynamic PET images was recently proposed to handle arbitrary shaped clusters in the space in which they are identified. While improved results were obtained with KSC compared to three state of art methods, its use for clinical applications is still hindered by the manual setting of several parameters. In this paper, we develop an extension of KSC to automatically estimate the parameters involved in the method and to make it deterministic. First, a global search procedure is used to locate the optimal cluster centroids from the projected data. Then an unsupervised clustering criterion is tailored and used in a global optimization scheme to automatically estimate the scale parameter and the weighting factors involved in the proposed Automatic and Deterministic Kinetic Spectral Clustering (AD-KSC). We validate the method using GATE Monte Carlo simulations of dynamic numerical phantoms and present results on real dynamic images. The deterministic results obtained with AD-KSC agree well with those obtained with optimal manual parameterization of KSC, and improve the ROI identification compared to three other clustering methods. The proposed approach could have significant impact for quantification of dynamic PET images in molecular imaging studies.
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- 2015
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25. 3D+t segmentation of PET images using spectral clustering
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Zbib, Hiba, Kdouh, Salam, Mouysset, Sandrine, Stute, Simon, Girault, Jean-Marc, Charara, Jamal, Nassereddme, Mohammad, Mcheik, Ali, Buvat, Irene, Tauber, Clovis, Commissariat à l'Energie Atomique et aux énergies alternatives - CEA (FRANCE), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Centre Hospitalier Régional Universitaire de Tours - CHU Tours (FRANCE), Université de Tours (FRANCE), Université Paris-Sud 11 (FRANCE), Imagerie et Cerveau (Tours, France), Université Libanaise, Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM), Algorithmes Parallèles et Optimisation (IRIT-APO), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Imagerie Moléculaire in Vivo (IMIV - U1023 - ERL9218), Service Hospitalier Frédéric Joliot (SHFJ), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National Polytechnique de Toulouse - INPT (FRANCE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
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Calcul parallèle, distribué et partagé ,Image segmentation ,Positron emission tomography ,3D+t segmentation ,Physics::Medical Physics ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Principal component analysis ,PET images ,Monte Carlo methods ,[INFO.INFO-DC]Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC] ,Medical image processing - Abstract
International audience; Segmentation of dynamic PET images is often needed to extract the time activity curve (TAC) of regions. While clustering methods have been proposed to segment the PET sequence, they are generally either sensitive to initial conditions or favor convex shaped clusters. Recently, we have proposed a deterministic and automatic spectral clustering method (AD-KSC) of PET images. It has the advantage of handling clusters with arbitrary shape in the space in which they are identified. While improved results were obtained with AD-KSC compared to other methods, its use for clinical applications is constrained to 2D+t PET data due to its computational complexity. In this paper, we propose an extension of AD-KSC to make it applicable to 3D+t PET data. First, a preprocessing step based on a recursive principle component analysis and a Global K-means approach is used to generate many small seed clusters. AD-KSC is then applied on the generated clusters to obtain the final partition of the data. We validated the method with GATE Monte Carlo simulations of Zubal head phantom. The proposed approach improved the region of interest (ROI) definition and outperformed the K-means algorithm.
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- 2015
26. Antifungal and Antiochratoxigenic Activities of Essential Oils and Total Phenolic Extracts: A Comparative Study
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Hiba Kawtharani, Rachelle El Khoury, Richard G. Maroun, Anthony El Khoury, André El Khoury, Florence Mathieu, Ali Atoui, Faculté des Sciences, Département des sciences de la vie et de la terres - Biochimie, Laboratoire de Mycologie et Sécurité des Aliments (LMSA), Université Saint-Joseph de Beyrouth (USJ), Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Saint-Joseph de Beyrouth - USJ (LEBANON), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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0301 basic medicine ,Antifungal ,Ochratoxin A ,Fungal growth ,Physiology ,medicine.drug_class ,030106 microbiology ,Clinical Biochemistry ,Aspergillus carbonarius ,Biochemistry ,High-performance liquid chromatography ,Article ,03 medical and health sciences ,chemistry.chemical_compound ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Botany ,medicine ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,biocontrol ,Food science ,Génie des procédés ,essential oils ,Molecular Biology ,2. Zero hunger ,total phenolic extracts ,SAGE ,lcsh:RM1-950 ,ochratoxin A ,Biocontrol ,Cell Biology ,lcsh:Therapeutics. Pharmacology ,030104 developmental biology ,chemistry ,Essential oils ,Total phenolic extracts - Abstract
International audience; This study is intended to prevent ochratoxin A (OTA) production by Aspergillus carbonarius S402 using essential oils (EOs) and total phenolic compounds extracted from plants and herbs. The EOs used in this study are the following: bay leaves, cumin, fenugreek, melissa, mint, and sage. As for the phenolic compounds, they were extracted from bay leaves, cumin, fenugreek, melissa, mint, sage, anise, chamomile, fennel, rosemary, and thyme. The experiments were conducted on Synthetic Grape Medium (SGM) medium at 28 °C for 4 days. OTA was extracted from the medium with methanol and quantified using HPLC (High Performance Liquid Chromatography). Results showed that EOs had a greater impact than the total phenolic extracts on the OTA production. Reduction levels ranged between 25% (sage) and 80% (melissa) for the EOs at 5 µL mL-1, and 13% (thyme) and 69% (mint) for the phenolic extracts. Although they did not affect the growth of A. carbonarius, total phenolic extracts and EOs were capable of partially reducing OTA production. Reduction levels depended on the nature of the plants and the concentration of the EOs. Reducing OTA with natural extracts could be a solution to prevent OTA production without altering the fungal growth, thus preserving the natural microbial balance.
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- 2017
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27. Reductive dimerization mechanisms of some streptocyanine dyes
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Marie-Pierre Maether, Fadia Najjar, Theo Tzedakis, Christiane André-Barrès, Corinne Payrastre, Peter Winterton, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Laboratoire de Génie Chimique - LGC (Toulouse, France), Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Lebanese University [Beirut] (LU), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT), Laboratoire de Génie Chimique (LGC), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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Cyclic voltammetry ,Dye ,Chemistry ,General Chemical Engineering ,Glassy carbon electrode ,Inorganic chemistry ,Kinetic energy ,Streptocyanine ,Electron transfer ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,Electrochemistry ,Génie chimique ,Convoluted current ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Current (fluid) ,Génie des procédés ,Dimerization - Abstract
International audience; Cyclic voltammetric studies of streptocyanine dyes were carried out on a glassy carbon electrode. For dye electroreduction, logarithmic analysis of the convoluted current indicates an EC2 mechanism with dimerization following electron transfer. Relevant kinetic and thermodynamic values are reported.
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- 2014
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28. Optimized spectral clustering for segmentation of dynamic PET images
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Jean-Marc Girault, Sandrine Mouysset, Laurent Galineau, Clovis Tauber, Irène Buvat, Hiba Zbib, Simon Stute, Sylvie Chalon, Jamal Charara, Lebanese University [Beirut] (LU), Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Algorithmes Parallèles et Optimisation (IRIT-APO), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Université Toulouse III - Paul Sabatier (UT3), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Imagerie et Modélisation en Neurobiologie et Cancérologie (IMNC (UMR_8165)), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'Energie Atomique et aux énergies alternatives - CEA (FRANCE), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Institut National de la Santé et de la Recherche Médicale - INSERM (FRANCE), Lebanese University - LU (LEBANON), Université de Paris Diderot - Paris 7 (FRANCE), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), Centre Hospitalier Régional Universitaire de Tours - CHU Tours (FRANCE), Université de Tours (FRANCE), Université Paris-Sud 11 (FRANCE), Imagerie et Cerveau (Tours, France), and Imagerie et Modélisation en Neurobiologie et Cancérologie - IMNC (Orsay, France)
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Image segmentation ,Positron emission tomography ,Clustering algorithms ,Computer science ,business.industry ,Segmentation-based object categorization ,Probabilistic logic ,Pattern recognition ,Indexes ,Spectral clustering ,Weighting ,Calcul parallèle, distribué et partagé ,Manuals ,Segmentation ,Computer vision ,Artificial intelligence ,[INFO.INFO-DC]Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC] ,business ,Cluster analysis ,Kinetic theory ,Noise ,Global optimization - Abstract
he quantification of dynamic PET images requires the definition of regions of interest. The manual delineation is a time consuming and unreproducible process due to the poor resolution of PET images. Approaches were proposed in the literature to classify the kinetic profiles of voxels, however, they are generally either sensitive to initial conditions or favor convex shaped clusters. Recently we have proposed a kinetic spectral clustering (KSC) method for segmentation of dynamic PET images that has the advantage of handling clusters with arbitrary shape in the space in which they are identified. However, its use for clinical applications is still hindered by the manual setting of several parameters. In this paper, we propose an extension of KSC to make it automatic (ASC). A new unsupervised clustering criterion is tailored and a global optimization by a probabilistic metaheuristic algorithm is used to select the scale parameter and the weighting factors involved in the method. We validate our approach with GATE Monte Carlo simulations. Results obtained with ASC compare closely with those obtained with optimal manual parameterization of KSC, and outperform those obtained with two other approaches from the literature.
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- 2013
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29. Simulating actions for learning
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Ali Awada, Philippe Saade, Philippe Joly, Équipe Structuration, Analyse et MOdélisation de documents Vidéo et Audio (IRIT-SAMoVA), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse 1 Capitole (UT1), Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse - Jean Jaurès - UT2J (FRANCE), Université Toulouse 1 Capitole - UT1 (FRANCE), and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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Computer science ,Simple Features ,02 engineering and technology ,Machine learning ,computer.software_genre ,01 natural sciences ,Action recognition ,[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI] ,Traitement des images ,[INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing ,0202 electrical engineering, electronic engineering, information engineering ,Traitement du signal et de l'image ,AdaBoost ,Hidden Markov model ,Synthèse d'image et réalité virtuelle ,Contextual image classification ,business.industry ,Late fusion Adaboost ,010401 analytical chemistry ,Cognitive neuroscience of visual object recognition ,[INFO.INFO-CV]Computer Science [cs]/Computer Vision and Pattern Recognition [cs.CV] ,Pattern recognition ,Vision par ordinateur et reconnaissance de formes ,Intelligence artificielle ,[INFO.INFO-GR]Computer Science [cs]/Graphics [cs.GR] ,0104 chemical sciences ,Maxima and minima ,Simulating actions ,ComputingMethodologies_PATTERNRECOGNITION ,[INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV] ,020201 artificial intelligence & image processing ,Artificial intelligence ,business ,computer ,Classifier (UML) - Abstract
International audience; This paper presents a novel approach for generating new actions to learn supervised algorithms such as the Adaboost in the context of human action recognition. Indeed, the learning process requires a large amount and variety of data. Our motivation in this work is to reduce the dependency on public databases and allow learning with small sets of actions. We overcome the problem of nondiscriminatory action datasets for action recognition by enlarging a set of actions performed by different persons in different ways and captured by a Kinect. We present a way to enlarge the originally captured dataset from a Kinect device or from simply annotated data. This is done by combining the extrema of the action sequences into intervals, creating random points within them, and adding certain variables to discriminate the samples. These actions are learned and tested with a late fusion Adaboost using simple features and a strong classifier for each joint. Finally, a confidence coefficient is calculated and used as input of a higher level Adaboost classifier.
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- 2013
30. Detecting range and coupling coefficient tradeoff with a multiple loops reader antenna for small size RFID LF tags
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Marjorie Grzeskowiak, S. Abou Chakra, Lionel Rousseau, A. Joisel, K. Wang, David Delcroix, Antoine Diet, T. Bouaziz, Stephane Protat, Christophe Conessa, Gaelle Lissorgues, Laboratoire des signaux et systèmes (L2S), Université Paris-Sud - Paris 11 (UP11)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS), DRE - Département de Recherche en Electromagnétisme, EMG - Département Electromagnétisme - L2S, Université Paris-Sud - Paris 11 (UP11)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-SUPELEC-Campus Gif, Ecole Supérieure d'Electricité - SUPELEC (FRANCE)-Ecole Supérieure d'Electricité - SUPELEC (FRANCE), Lebanese University [Beirut] (LU), Electronique, Systèmes de communication et Microsystèmes (ESYCOM), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris, Conservatoire National des Arts et Métiers - CNAM (FRANCE), Centre National de la Recherche Scientifique - CNRS (FRANCE), Ecole de l'Innovation Technologique - ESIEE PARIS (FRANCE), Lebanese University - LU (LEBANON), Sorbonne Université (FRANCE), CentraleSupélec (FRANCE), Université Paris-Est Marne-La-Vallée - UPEM (FRANCE), Université Paris-Sud 11 (FRANCE), Laboratoire Electronique, Systèmes de communication et Microsystèmes - ESYCOM (Marne-la-Vallée, France), Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Laboratoire Génie électrique et électronique de Paris (GeePs), Centre National de la Recherche Scientifique (CNRS)-CentraleSupélec-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris-Sud - Paris 11 (UP11), Institut d’Électronique, de Microélectronique et de Nanotechnologie (IEMN) - UMR 8520 (IEMN), Institut supérieur de l'électronique et du nunérique (ISEN)-Université Polytechnique Hauts-de-France (UPHF)-Ecole Centrale de Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS), and Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Paris-Est Marne-la-Vallée (UPEM)-ESIEE Paris
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Equations ,Computer science ,Electromagnétisme ,02 engineering and technology ,Low frequency ,Security token ,[SPI.MAT]Engineering Sciences [physics]/Materials ,0202 electrical engineering, electronic engineering, information engineering ,Electronic engineering ,Range (statistics) ,[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics ,[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials ,Inductance ,ComputingMilieux_MISCELLANEOUS ,Magnetic flux ,RFID ,Directional antenna ,020208 electrical & electronic engineering ,Volume (computing) ,020206 networking & telecommunications ,[SPI.TRON]Engineering Sciences [physics]/Electronics ,[SPI.ELEC]Engineering Sciences [physics]/Electromagnetism ,Couplings ,Antennas ,Antenna (radio) ,RFID tags ,Coupling coefficient of resonators - Abstract
International audience; This paper summarizes some tests with Low Frequency (LF, 125 kHz) RFID tags of two types: Card and Token. These tests were done in order to evaluate the feasibility of an identification/traceability of tags which size is constrained and supposed to be detected inside a delimited volume of 40×40×10 cm 3 . As the size of the antenna tag is supposed to be very small, we improve the detection range and volume of definition by designing different reader antennas. Reader antennas presented are of two types whether they are based on single (SL) or multiple loops (ML). Detection range was evaluated for planar antennas (3 SL and one ML). Volume of definition for the detection was estimated by designing two-level prototypes of ML antennas. Results are discussed about the optimization possibility of detection range and volume thanks to ML.
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- 2012
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31. Comparison of diffusivities data of streptocyanine dyes by electrochemical and NMR-DOSY methods
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Pierre Lavedan, Fadia Najjar, Theodore Tzedakis, Marie-Pierre Maether, Christiane André-Barrès, Corinne Payrastre, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - INPT (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Service commun de Résonance Magnétique Nucléaire - RMN (Toulouse, France), Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Lebanese University [Beirut] (LU), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT), Laboratoire de Génie Chimique (LGC), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Institut de Chimie de Toulouse (ICT-FR 2599), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Laboratoire de génie chimique [ancien site de Basso-Cambo] (LGC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, and Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE)
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Self-diffusion ,NMR-DOSY ,General Chemical Engineering ,Diffusion ,Biochimie, Biologie Moléculaire ,Analytical chemistry ,010402 general chemistry ,Thermal diffusivity ,Electrochemistry ,01 natural sciences ,Analytical Chemistry ,chemistry.chemical_compound ,[CHIM.GENI]Chemical Sciences/Chemical engineering ,TRACER ,Génie chimique ,[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Acetonitrile ,Génie des procédés ,Diffusion coefficient ,010405 organic chemistry ,Limiting current ,0104 chemical sciences ,Convolution potential sweep voltammetry ,Solvent ,chemistry ,Deuterium ,Mutual diffusion - Abstract
International audience; Diffusivity data of streptocyanine dyes in acetonitrile were investigated using both transient voltammetric techniques and NMR-DOSY. Results of voltammetric measurements allow determination of the diffusion coefficient D values in the range of 1.2-1.6 x 10-9 m² s-1 for the target dyes. Deuterated acetonitrile solvent was used for NMR-DOSY experiments and diffusivities of streptocyanines are given after calibration of acetonitrile on its tracer diffusion value of D∗ACN of 4.37 x 10-⁹. The results for the two methods appear to be in good agreement allowing use of the convenient NMR-DOSY method to measure diffusivity of streptocyanine dyes at low concentrations and so giving a direct access to the number of exchanged electrons using limiting current electrochemical techniques. This last method affords a great advantage of obtaining diffusion coefficients by non-electrochemical method.
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- 2012
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32. Modeling of Rayleigh-Bénard natural convection heat transfer in nanofluids
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C. Fakih, Glades Bachir, Abdelkader Mojtabi, Marie-Catherine Charrier-Mojtabi, Bilal Elhajjar, Institut de mécanique des fluides de Toulouse (IMFT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées, Lebanese University [Beirut] (LU), Laboratoire Physique de l'Homme Appliquée à Son Environnement (PHASE), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Physique de l'Homme Appliquée à Son Environnement - PHASE (Toulouse, France), and Institut National Polytechnique de Toulouse - INPT (FRANCE)
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Materials science ,Convective heat transfer ,020209 energy ,Strategy and Management ,Mécanique des fluides ,Thermodynamics ,02 engineering and technology ,Heat transfer coefficient ,Nanofluid ,Rayleigh–Bénard ,Convection ,01 natural sciences ,010305 fluids & plasmas ,[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph] ,Physics::Fluid Dynamics ,Combined forced and natural convection ,Rayleigh-Bénard ,0103 physical sciences ,Heat transfer ,0202 electrical engineering, electronic engineering, information engineering ,Media Technology ,General Materials Science ,[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph] ,Marketing ,Natural convection ,Rayleigh number ,Forced convection - Abstract
International audience; Heat transfer in Rayleigh-Bénard convection is investigated for three types of nanofluid. Instead of using the expressions commonly found in the literature for specific heat capacity and thermal expansion coefficient, we used two relations that are in agreement with the laws of thermodynamics. The influence of nanoparticles on conductive and convective heat transfer is studied. It is shown that adding nanoparticles in a fluid delays the onset of convection. Contrary to what is argued by many authors, we prove by direct numerical simulations that the use of nanofluids can reduce heat transfer instead of increasing it.
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- 2010
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33. First computational evidence of a competitive stepwise and concerted mechanism for the reduction of antimalarial endoperoxides
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Christiane André-Barrès, Fadia Najjar, Corinne Lacaze-Dufaure, Centre interuniversitaire de recherche et d'ingenierie des matériaux (CIRIMAT), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC), Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Institut de Chimie de Toulouse (ICT-FR 2599), Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Lebanese University [Beirut] (LU), Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), and Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)
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Stereochemistry ,Matériaux ,010402 general chemistry ,Cleavage (embryo) ,01 natural sciences ,DFT ,[SPI.MAT]Engineering Sciences [physics]/Materials ,Electron Transport ,Reduction (complexity) ,Antimalarials ,Electron transfer ,Materials Chemistry ,Physical and Theoretical Chemistry ,Stable conformations ,010405 organic chemistry ,Chemistry ,Concerted reaction ,Models, Theoretical ,Artemisinins ,Peroxides ,0104 chemical sciences ,3. Good health ,Surfaces, Coatings and Films ,Marcus theory ,Quantum Theory ,Oxidation-Reduction - Abstract
International audience; We study structural analogues of endoperoxides belonging to the family of G factors which present moderate to good antimalarial activity. Their biological activity is related to the reduction and cleavage of the O-O bond. Generally, the O-O bond reduction of model endoperoxides, as well as artemisinin, occurs by a concerteddissociative electron transfer (ET) mechanism. For the G3 and G3Me compounds, the experimental counterpart indicates an unexpected competition between a concerted and a stepwise mechanism, but no intermediate species can be isolated. We thus perform DFT studies on the reduction of G3 and G3Me compounds. We confirm the formation of an intermediate radical anion followed by cleavage of the O-O bond in a secondstep. We characterize the stable conformations for the radical anions G3•- and G3Me•- resulting from the ET and the associated reaction pathway. We also calculate the reorganization energy upon ET in relation to the Marcus theory using the DFT method. These results provide valuable insight into understanding the biological activity of G-factor endoperoxides as potential therapeutic antimalarial agents.
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- 2010
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34. The creation and monitoring of a network for solid healthcare waste management
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Dany Obeid, Fady Moujaes, Dominique Salameh, Cédric Brandam, Olivia Maamari, Robert Keyrouz, Michèle Kosremelli Asmar, Roger Lteif, Centre National de la Recherche Scientifique - CNRS (FRANCE), Institut National Polytechnique de Toulouse - Toulouse INP (FRANCE), Lebanese University - LU (LEBANON), Université Toulouse III - Paul Sabatier - UT3 (FRANCE), arcenciel (LEBANON), Université Saint-Joseph de Beyrouth - USJ (LEBANON), Laboratoire de Génie Chimique - LGC (Toulouse, France), Institut National Polytechnique de Toulouse - INPT (FRANCE), Université Saint-Joseph de Beyrouth (USJ), Faculty of Engineering [Lebanese University] (ULFG), Lebanese University [Beirut] (LU), Laboratoire de Génie Chimique (LGC), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), and Université Fédérale Toulouse Midi-Pyrénées
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Strategic plan ,Engineering ,Environmental Engineering ,Quality management ,Process (engineering) ,Network ,Context (language use) ,12. Responsible consumption ,11. Sustainability ,Health care ,Génie chimique ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering ,Génie des procédés ,Waste Management and Disposal ,Sustainable development ,Strategic planning ,Waste management ,[SDE.IE]Environmental Sciences/Environmental Engineering ,business.industry ,Waste minimisation ,Management ,3. Good health ,Treatment ,HCW ,Fuel efficiency ,Healthcare waste ,business - Abstract
International audience; Healthcare waste mismanagement constitutes a serious environmental and sanitary problem, especially in developing countries. This article describes the strategy and the methodology of the implementation of a national network for healthcare waste management by a non-profit organisation in Lebanon, taking into consideration environmental, social and economic issues. It presents a holistic description of the main aspects of this crucial sustainable development topic: the elaboration of the strategy and the selection of the optimal treatment technique based on an analysis of the context; the training on waste minimisation and waste management issues inside hospitals; the waste transportation and treatment procedures; the quality management of the process; the evaluation and the monitoring of the produced quantities and the established system; the optimisation of sterilisation parameters and process in order to reduce sterilisation time and fuel consumption.
- Published
- 2015
- Full Text
- View/download PDF
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