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2. Analysis of Clinical Criteria for Discharge Among Patients Hospitalized for COVID-19: Development and Validation of a Risk Prediction Model.

Author

Schnipper, Jeffrey, Oreper, Sandra, Hubbard, Colin, Kurbegov, Dax, Egloff, Shanna, Najafi, Nader, Valdes, Gilmer, Siddiqui, Zishan, O Leary, Kevin, Horwitz, Leora, Lee, Tiffany, and Auerbach, Andrew

Subjects
COVID-19, hospital readmission, risk assessment
Abstract

BACKGROUND: Patients hospitalized with COVID-19 can clinically deteriorate after a period of initial stability, making optimal timing of discharge a clinical and operational challenge. OBJECTIVE: To determine risks for post-discharge readmission and death among patients hospitalized with COVID-19. DESIGN: Multicenter retrospective observational cohort study, 2020-2021, with 30-day follow-up. PARTICIPANTS: Adults admitted for care of COVID-19 respiratory disease between March 2, 2020, and February 11, 2021, to one of 180 US hospitals affiliated with the HCA Healthcare system. MAIN MEASURES: Readmission to or death at an HCA hospital within 30 days of discharge was assessed. The area under the receiver operating characteristic curve (AUC) was calculated using an internal validation set (33% of the HCA cohort), and external validation was performed using similar data from six academic centers associated with a hospital medicine research network (HOMERuN). KEY RESULTS: The final HCA cohort included 62,195 patients (mean age 61.9 years, 51.9% male), of whom 4704 (7.6%) were readmitted or died within 30 days of discharge. Independent risk factors for death or readmission included fever within 72 h of discharge; tachypnea, tachycardia, or lack of improvement in oxygen requirement in the last 24 h; lymphopenia or thrombocytopenia at the time of discharge; being ≤ 7 days since first positive test for SARS-CoV-2; HOSPITAL readmission risk score ≥ 5; and several comorbidities. Inpatient treatment with remdesivir or anticoagulation were associated with lower odds. The models AUC for the internal validation set was 0.73 (95% CI 0.71-0.74) and 0.66 (95% CI 0.64 to 0.67) for the external validation set. CONCLUSIONS: This large retrospective study identified several factors associated with post-discharge readmission or death in models which performed with good discrimination. Patients 7 or fewer days since test positivity and who demonstrate potentially reversible risk factors may benefit from delaying discharge until those risk factors resolve.

Published
2024

4. Peer and Teacher Preference, Student-Teacher Relationships, Student Ethnicity, and Peer Victimization in Elementary School

Author

Wang, Feihong, Leary, Kevin A., Taylor, Lorraine C., and Derosier, Melissa E.

Abstract

We examined the effects of peer preference and teacher preference for students, students' perceived relationship with their teacher and student ethnicity on peer victimization in late elementary school. Participants were students in the third through fifth grades in four public elementary schools in a southern state. Using hierarchical linear modeling, we found that peer and teacher preference for students and student ethnicity each uniquely predicted student-reported peer victimization, controlling for student gender, grade level, and teacher gender and race. Specifically, higher peer and teacher preference were independently related to lower peer victimization in late elementary school, and minority students were more at risk for peer victimization than were White students. Interestingly, examinations of interactions indicated that Hispanic children who reported more positive relationships with teachers were at greater risk of victimization relative to White students. Practical implications are discussed in light of these findings. [This article was published in "Psychology in the Schools" (EJ1097179).]

Published
2016
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9. An Effective Implementation of Remote Workplace Practices to Address Unprecedented Challenges During the COVID-19 Pandemic: The Case of Adobe Inc.

Author

Leary, Terence, Alderman, Neil, and Leary, Kevin

Subjects
COVID-19 pandemic, JOB involvement, PANDEMICS, PROFITABILITY
Abstract

The COVID-19 pandemic made it imperative for businesses to function remotely to both protect the health of their employees while staying afloat and preventing a global recession. This article highlights the success of Adobe Inc. in pre-empting the detrimental effects of the pandemic on workplace issues. Adobe provided an atmosphere of greater flexibility and autonomy through the effective modification of workplace practices to achieve this goal. This led to a very positive, strong association among engaged/invested workers with enhanced profitability and business results. The outcome of these modifications provides a prototype for other organizations to enhance both employee engagement and profitability, especially during perilous times. [ABSTRACT FROM AUTHOR]

Published
2023

34. Predictive Markers of High-Grade or Serious Treatment-Emergent Infections with Daratumumab-Based Regimens in Newly Diagnosed Multiple Myeloma (NDMM)

Author

van de Donk, Niels W. C. J., primary, Zweegman, Sonja, additional, San-Miguel, Jesus F., additional, Dimopoulos, Meletios A, additional, Cavo, Michele, additional, Suzuki, Kenshi, additional, Touzeau, Cyrille, additional, Usmani, Saad Z., additional, Perrot, Aurore, additional, Pei, Huiling, additional, Kudva, Anupa, additional, Van Rampelbergh, Rian, additional, Ukropec, Jon, additional, Leary, Kevin, additional, Carson, Robin, additional, Qi, Ming, additional, and Chari, Ajai, additional

Published
2020
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48. Denise speaks

Author

Leary, Kevin O'

Subjects
Motion picture actors and actresses -- Interviews, Separation (Law), General interest
Abstract

Popular movie actor Denise Richards discuss about her separation from husband Charlie Sheen.

Published
2006

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