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Your search keyword '"Leanza, Gabriele Maria"' showing total 10 results
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10 results on '"Leanza, Gabriele Maria"'

2. A 67-Year-Old Man with Chronic Lymphocytic Leukemia (CLL) on Maintenance Therapy with Ibrutinib with Persistent SARS-CoV-2 Infection Unresponsive to Antiviral Treatments

Author

Sanmartin, Flavia, primary, Magrini, Eugenia, additional, Rando, Emanuele, additional, Del Giacomo, Paola, additional, Dusina, Alex, additional, Matteini, Elena, additional, Carbone, Andrea, additional, Puma, Giuseppe, additional, Leanza, Gabriele Maria, additional, Frondizi, Federico, additional, Innocenti, Idanna, additional, Maiuro, Giuseppe, additional, Liotti, Flora Marzia, additional, Santangelo, Rosaria, additional, Laurenti, Luca, additional, and Cingolani, Antonella, additional

Published
2024
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3. Cerebrospinal fluid drain infection caused by pandrug-resistant Staphylococcus epidermidis successfully treated with ceftaroline in combination with fosfomycin and vancomycin

Author

MAGRINI, Eugenia, primary, RANDO, Emanuele, additional, GIACOMO, Paola DEL, additional, MATTEINI, Elena, additional, LEANZA, Gabriele Maria, additional, SANMARTIN, Flavia, additional, CARBONE, Andrea, additional, MAIURO, Giuseppe, additional, DUSINA, Alex, additional, and CINGOLANI, Antonella, additional

Published
2024
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5. Safety and Efficacy of a Single Procedure of Extraction and Reimplantation of Infected Cardiovascular Implantable Electronic Device (CIED) in Comparison with Deferral Timing: An Observational Retrospective Multicentric Study

Author

Tascini, Carlo, primary, Giuliano, Simone, additional, Attanasio, Vittorio, additional, Segreti, Luca, additional, Ripoli, Andrea, additional, Sbrana, Francesco, additional, Severino, Sergio, additional, Sordelli, Chiara, additional, Weisz, Sara Hana, additional, Zanus-Fortes, Agnese, additional, Leanza, Gabriele Maria, additional, Carannante, Novella, additional, Di Cori, Andrea, additional, Bongiorni, Maria Grazia, additional, Zucchelli, Giulio, additional, and De Vivo, Stefano, additional

Published
2023
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8. Cerebrospinal Fluid Drain Infection Caused by Pandrug-Resistant Staphylococcus Epidermidis Successfully Treated with Ceftaroline in Combination with Fosfomycin and Vancomycin

Author

Magrini, Eugenia, primary, Rando, Emanuele, additional, Del Giacomo, Paola, additional, Matteini, Elena, additional, Leanza, Gabriele Maria, additional, Sanmartin, Flavia, additional, Carbone, Andrea, additional, Maiuro, Giuseppe, additional, Dusina, Alex, additional, and Cingolani, Antonella, additional

Published
2023
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9. Risk factors for fragility fractures in type 1 diabetes

Author

Leanza, Gabriele Maria, Maddaloni, E., Pitocco, Dario, Conte, C., Palermo, Ofelia Anna, Maurizi, A. R., Pantano, A. L., Suraci, C., Altomare, M., Strollo, R., Manfrini, S., Pozzilli, P., Schwartz, A. V., Napoli, N., Leanza G., Pitocco D. (ORCID:0000-0002-6220-686X), Palermo A., Leanza, Gabriele Maria, Maddaloni, E., Pitocco, Dario, Conte, C., Palermo, Ofelia Anna, Maurizi, A. R., Pantano, A. L., Suraci, C., Altomare, M., Strollo, R., Manfrini, S., Pozzilli, P., Schwartz, A. V., Napoli, N., Leanza G., Pitocco D. (ORCID:0000-0002-6220-686X), and Palermo A.

Abstract

Objective: To determine clinical diabetes-related risk factors for fragility fractures in type 1 diabetes (T1D). Research design and methods: History of bone fragility fractures occurring after T1D diagnosis was assessed by questionnaire in this cross-sectional study in 600 T1D subjects. Glycated hemoglobin A1c (HbA1c)over the previous 5 years was used as an index of long-term glycemic control; complications were adjudicated by physician assessment. Multinomial logistic regression models were used to assess the associations between diabetes-related risk factors and fracture history. Results: One-hundred-eleven patients (18.5%)reported at least one fracture; of these 73.8% had only one and 26.2% had more than one fracture. Average age was 41.9 ± 12.8 years, with even gender distribution; disease duration was 19.9 ± 12.0 years; and BMI was 24.4 ± 3.7 kg/m2. The 5-year average HbA1c was 7.6 ± 1.0% (60 mmol/mol). In adjusted models, reduced risk for 1 fracture was found in those with higher creatinine clearance rate (CCr)(RRR 0.22 [95% CI: 0.06–0.83]for 1 unit increase in lnCCr, p = 0.03)and increased risk in those with neuropathy (RRR 2.57 [1.21–5.46], p = 0.01). Increased risk for ≥2 fractures was found in subjects in the highest tertile of HbA1c (≥7.9%)compared with the lowest tertile (≤7.17%)(RRR 3.50 [1.04–11.7], p = 0.04)and of disease duration (≥26 years versus <14 years)(RRR 7.59 [1.60–35.98], p = 0.01). Conclusions: Poor glycemic control and long exposure to the disease are independent diabetes-related risk factors for multiple bone fractures in T1D.

Published
2019

10. Pragmatic overview on acute bacterial and fungal infections of the central nervous system: a holistic update from diagnosis to treatment.

Author

Giuliano S, Flammini S, Zanus-Fortes A, Montanari L, Leanza GM, Attanasio V, Pecori D, Sbrana F, and Tascini C

Subjects
Humans, Central Nervous System, Meningitis, Mycoses diagnosis, Mycoses drug therapy
Abstract

Although progress has led to a drop in infections, meningitis still represents a threat worldwide, affecting some areas more than others. As a medical emergency, it requires prompt recognition and treatment. Moreover, diagnosis relies on invasive methods, while representing a tug-of-war with timely therapeutic interventions, since delays are burdened by mortality and life-long sequalae. While counterbalancing the overuse of antimicrobials, it is imperative to assess correct interventions in order to optimize treatments and reduce negative outcomes. Because the drop in mortality and consequences has been consistent, although not as impactful as with other vaccine-preventable diseases, the WHO has traced a roadmap detailing actions to reduce the meningitis burden by 2030. There are currently no updated guidelines, whereas novel diagnostic methods as well as pharmacological interventions are increasing, along with the shifting epidemiology. In light of the above, this paper wishes to summarize existing data and evidences and suggest potential novel solutions to a complex problem.

Published
2023

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