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1. Pushing the boundaries. Concurrent Hodgkin lymphoma and breast cancer treatment with preservation of pregnancy: A case report

Author: LeJeune Charlotte, Dierickx Daan, Wildiers Hans, Lannoo Lore, Van Calsteren Kristel, Vandecaveye Vincent, Menten Björn, Vermeesch Joris, and Amant Frédéric
Subjects: Pregnancy, Breast cancer, Hodgkin lymphoma, Case report, Gynecology and obstetrics, RG1-991, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Background: Breast cancer and hematological cancers are the most commonly diagnosed malignancies during pregnancy. This case report is the first to describe the ultimate challenge to preserve a pregnancy while the expectant mother is diagnosed and treated simultaneously for two concurrent primary malignancies, a stage IIA Hodgkin lymphoma and pT2N0(Sn) breast cancer. Clinical case: A 36-year-old pregnant primigravida underwent a routine non-invasive prenatal test at 14 weeks and 4 days of gestation. Genome-wide sequencing was used and revealed an aberrant DNA/chromosome copy number profile among which a strong 2p-gain, possibly related to a maternal malignancy. Physical examination showed an enlarged cervical lymph node and ultrasound guided biopsy confirmed the diagnosis of a nodular sclerosing classical Hodgkin lymphoma subsequently staged as an early stage, unfavorable (IIA) Hodgkin lymphoma. Whole body magnetic resonance imaging for further staging also indicated a suspicious nodule in the right breast. Further investigation resulted in the concurrent diagnosis of a pT2N0(Sn) invasive ductal adenocarcinoma. Patient underwent a mastectomy with sentinel lymph node biopsy at 15 weeks and 5 days of gestation, followed by 4-weekly chemotherapy administration, consisting of doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD). Pregnancy went further relatively uncomplicated and fetal assessment was reassuring during pregnancy. Due to fever of unknown origin and preterm labor, a cesarean section was performed on a gestational age of 35 weeks and 4 days. Oncological treatment was completed after delivery with involved-field radiation therapy for the Hodgkin lymphoma. Completion of systemic treatment for breast cancer consisted of docetaxel/cyclophosphamide chemotherapy, and anti-hormonal treatment in the form of ovarian function suppression and letrozole. Conclusion: Here we show for the first time that two concurrent primary malignancies can be treated successfully during pregnancy with respect to maternal and fetal chances. Motivated modifications of breast cancer treatment (mastectomy instead of lumpectomy, AVBD instead of epirubicin-cyclophosphamide chemotherapy), allowed treatment of both cancers during pregnancy. Final treatment was administered after delivery.
Published: 2022
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2. Epithelial ovarian cancer and borderline tumors during pregnancy: a report from the International Network on Cancer, Infertility, and Pregnancy

Author: Fruscio, Robert, Trozzi, Rita, Galimberti, Stefania, LeJeune, Charlotte, Van Calsteren, Kristel, Delle Marchette, Martina, Cardonick, Elyce, Mascilini, Floriana, Halaska, Michael, Peters, Inge, Fagotti, Anna, and Amant, Frederic
Published: 2025
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3. Child outcomes after prenatal exposure to platinum and taxane-based chemotherapy: an unplanned interim analysis of the international network on cancer, infertility, and pregnancy study

Author: Van Assche, Indra A., Van Calsteren, Kristel, Huis in ’t Veld, Evangeline A., van Gerwen, Mathilde, Heylen, Laura, LeJeune, Charlotte L., Cardonick, Elyce, Halaska, Michael J., Fruscio, Robert, Fumagalli, Monica, van Dijk-Lokkart, Elisabeth M., Lemiere, Jurgen, van Grotel, Martine, Lagae, Lieven, van den Heuvel-Eibrink, Marry M., and Amant, Frédéric
Published: 2024
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4. Long-term neurocognitive, psychosocial, and physical outcomes after prenatal exposure to radiotherapy: a multicentre cohort study of the International Network on Cancer, Infertility, and Pregnancy

Author: Van Assche, Indra A, Van Calsteren, Kristel, Lemiere, Jurgen, Hohmann, Jana, Blommaert, Jeroen, Huis in 't Veld, Evangeline A, Cardonick, Elyce, LeJeune, Charlotte, Ottevanger, Nelleke P B, Witteveen, Els P O, van Grotel, Martine, van den Heuvel-Eibrink, Marry M, Lagae, Lieven, Lambrecht, Maarten, and Amant, Frédéric
Published: 2024
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5. m-PIMA™ HIV1/2 VL: A suitable tool for HIV-1 and HIV-2 viral load quantification in West Africa

Author: Diop-Ndiaye, Halimatou, Sène, Pauline Yacine, Coulibaly, Khadidiatou, Diallo, Marième, Diallo, Sada, Diop, Karim, Sow-Ndoye, Aissatou, Fall, Mengue, Ndiaye, Anna Julienne Selbe, Mathebula, Evans, Ba, Adjratou Aissatou, Lejeune, Charlotte, Manga, Ndeye Marie Pascaline, Camara, Makhtar, Ndour, Cheikh Tidiane, and Kane, Coumba Toure
Published: 2024
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6. Successful cervical cancer treatment during a monochorionic diamniotic twin pregnancy in a patient with history of preterm delivery

Author: LeJeune, Charlotte, Trozzi, Rita, Mearadji, Banafsche, Painter, Rebecca, and Amant, Frédéric
Published: 2022
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7. COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

Author: Aeschlimann, Florence, Agard, Christian, Ait-Abdallah, Nassim, Albert, Jean-David, Alcais, Didier, Allain, Jean-Sébastien, Allanore, Yannick, Amador-Borreiro, Blanca, Amoura, Zahir, Andre, Emma, Arbault, Anaïs, Arlet, Jean-Benoît, Arnaud, Laurent, Arniaud, Denis, Arty-Hue, Herliette, Atlan, Lucie, Audemard-Verger, Alexandra, Audoin-Pajot, Christine, Audren, Victor, Bach-Bunner, Maxime, Bacquet-Deschryver, Hélène, Bader-Meunier, Brigitte, Balandraud, Nathalie, Balblanc, Jean-Charles, Bally, Stéphane, Banal, Frédéric, Barbery, Pierre, Barnetche, Thomas, Barrelet, Audre, Basch, André, Baumier, Vincent, Bayer, Guillaume, Bayle, Sophie, Beauvais, Catherine, Beinat, Rudie, Belin, Véronique, Belkhir, Rakiba, Benainous, Ruben, Belot, Alexandre, Benammar, Mohammed, Benhamou, Mathilde, Benhamou, Ygal, Benmansour, Ahmed, Bennet, Pascal, Bernoux-Manat, Brigitte, Berthet, Elise, Berthoux, Emilie, Bertolini, Ewa, Bigot, Adrien, Bisson-Vaivre, Aurélia, Blaison, Gilles, Bolla, Gilles, Bonidan, Olivier, Bonnet, Christine, Borie, Raphaël, Bossert, Marie, Boudou, Laurence, Bouhour, Françoise, Bouiller, Kévin, Bouldoires, Bastien, Boussoualim, Karima, Bouvard, Eric, Brondino, Regine, Buchlin, Pierre, Cabantous, Laurence, Cacoub, Patrice, Cadiou, Simon, Carteni, Maurizio, Carbasse, Aurélia, Castel, Brice, Cathebras, Pascal, Caumont, Hervé, Celant, Annalisa, Chaigne, Benjamin, Chaillous, Benoît, Champy, Romuald, Charcot, Agnès, Charles, Pierre, Charlot-Lambrecht, Isabelle, Charpin, Caroline, Chatelus, Emmanuel, Chaudier, Bernard, Chertok, Pascale, Chevalier, Xavier, Chevreau, Maxime, Chotard, Emilie, Chu Miow Lin, Delphine, Clavel, Gaëlle, Clavel-Osorio, Cyril, Cohen, Fleur, Cohen, Gregory, Colette-Cedoz, Marie-Eve, Collercandy, Nived, Colombey, Antoine, Comarmond, Chloé, Combe, Bernard, Comparon, Céline, Constant, Elodie, Coquerelle, Pascal, Corli, Justine, Corre, Clémence, Costedoat-Chalumeau, Nathalie, Couret, Marie, Courvoisier, Natacha, Coury-Lucas, Fabienne, Coutarel, Cécile, Coutier, Fabrice, Damade, Richard, Daver-Malaterre, Laurence, Dehimat, Sarahe, Delahousse, Michel, Barrois-Delattre, Emilie, Denarie, Delphine, Deprouw, Camille, Dernis, Emanuelle, Deroux, Alban, Desbarbieux, Renaud, Descamps, Elise, Deslandre, Chantal, Desmurs, Marie, Despaux, Jacques, Desplats, Marie, Detree, Frédérick, Devauchelle-Pensec, Valérie, Dhote, Robin, Dieude, Philippe, Dieudonne, Yannick, Diot, Elisabeth, Direz, Guillaume, Djeddi, Djamal-Dine, Douvier, Sarah, Drouet, Béatrice, Drumez, Elodie, Duc, Catherine, Ducornet, Angélique, Dufauret-Lombard, Carine, Duhamel, Alain, Dumaine, Cécile, Dumel, Anne-Elisabeth, Dumoulin-Richez, Chantal, Duquesne, Agnès, Durand, Géraldine, Durandin-Truffinet, Mariane, Duret, Pierre-Marie, Duval, Maïka, Ebbo, Mikaël, Ebstein, Esther, Economu-Dubosc, Andra, Emilie, Stéphanie, Euvrard, Romain, Evon, Philippe, Fabre, Sylvie, Fagedet, Dorothée, Farhat, Meryem, Fauconier, Marion, Fechtenbaum, Jacques, Felten, Renaud, Fernandes, Fanny, Ferreira-Maldent, Nicole, Feurer, Elodie, Fichet, Amandine, Flaisler, Françoise, Florens, Nans, Foltz, Violaine, Fontanges, Elisabeth, Foret, Jennifer, Fougerousse, Anne-Claire, Fouque-Aubert, Anne, Foutrier-Morello, Catherine, Francois-Pradier, Hélène, Frantzen, Léa, Fritz, Pierre, Froissart, Antoine, Fulpin, Jean, Fuzibet, Piera, Gaches, Francis, Gagneux-Lemoussu, Laurence, Penhoat-Gahier, Mélanie, Galland, Joris, Gandjbakhch, Frédérique, Garnier, Nicole, Garraud, Thomas, Garrot, Jean-François, Gastaldi, Romain, Gaud-Listrat, Véronique, Gauthier-Prieur, Maud, Georgescu, Dana, Gerard, Nathalie, Gervais, Elisabeth, Gibert, Christelle, Gibert, Eric, Gill, Ghislaine, Gillard, Jérôme, Gilson, Mélanie, Gimonnet, Pauline, Giraudet-Le Quintrec, Jeanine-Sophie, Giraud-Morelet, Aude, Glace, Baptiste, Glanowski, Camille, Godeau, Bertrand, Gombert, Bruno, Gonnet-Gracia, Camille, Goulenok, Tiphaine, Goupille, Philippe, Gourmelen, Olivier, Govindaraju-Audouard, Sophie, Grados, Franck, Grall-Lerosey, Martine, Grardel, Bruno, Grasland, Anne, Grateau, Gilles, Groza, Monica, Guillaud, Constance, Guillaume, Séverine, Guillibert, Caroline, Guillot, Xavier, Guilpain, Philippe, Gury, Aline, Guyot, Marie-Hélène, Hacquard-Bouder, Cécile, Havard, Marie-Noelle, Hellier, Jean-Pierre, Hennequin, Pascal, Henriot, Basile, Henry, Julien, Hentgen, Véronique, Hermet, Marion, Herasse, Muriel, Hernandez, Julie, Hie, Miguel, Hilliquin, Pascal, Hinschberger, Olivier, Hittinger-Roux, Ambre, Holubar, Jan, Hudry, Christophe, Huguenel, Serge, Jaccard, Clara, Jacquemier, Jean-Michel, Jamard, Bénédicte, Jan, Catherine, Jean, Sylvie, Jouvray, Mathieu, Juge, Pierre-Antoine, Juillard, Laurent, Jullien, Denis, Kabala, Anna, Kabchou, Abdelkrim, Karkowski, Ludovic, Karman, Françoise, Kemiche, Farid, Keraen, Jérémy, Kieffer, Pierre, Kone-Paut, Isabelle, Koreichi, Abdeldajallil, Kostine, Marie, La Batide Alanore, Sylvain, Lafforgue, Pierre, Lahalle, Sophie, Lambert, Marc, Lambrecht, Isabelle, Lanot, Sylvain, Lanteri, Aurélia, Larbre, Jean-Paul, Latourte, Augustin, Lavigne, Christian, Le Guen Guegan, Sophie, Le Guenno, Guillaume, Leguy, Diane, Lebrun, Agnès, Ledoult, Emmanuel, Legoupil, Nathalie, Legrand, Erick, Lejeune, Charlotte, Leloire, Olivier, Leroux, Christophe, Leroy, Rémi, Leroy-Gouix, Marie, Leturcq, Tifenn, Leurs, Amélie, Leveque-Michaud, Céline, Limbach, François-Xavier, Liote, Frédéric, Lohse, Anne, Lozac'h, Pierre, Lucas, Virginie, Madelon, Aurélie, Magy-Bertrand, Nadine, Mahevas, Matthieu, Maillard, Hélène, Maillet, Thibault, Malochet-Guinamand, Sandrine, Mangon, Quentin, Marchou-Lopez, Sylvie, Margarit, Nathalie, Marhadour, Thierry, Mariette, Xavier, Martin, Claire, Mathian, Alexis, Maurier, François, Maury, Frédéric, Mazet-Guillaume, Betty, Mazouyez, Arnaud, Mazyad, Hassan, Mehsen-Cetre, Nadia, Meinzer, Ulrich, Melki, Isabelle, Messer, Laurent, Miceli, Corinne, Michaud, Martin, Michel, Catherine, Michel, Matthias, Michon, Mathilde, Milesi-Lecat, Anne-Marie, Molto, Anna, Moly, Marie, Moranne, Olivier, Morel, Gautier, Morel, Hugo, Morel, Jacques, Morin, Franck, Moulinier, Laurence, Moulis, Guillaume, Moura, Bertrand, Nguyen, Minh, Nicolas-Vullierme, Sabine, Nielly, Hubert, Nocturne, Gaétane, Nottez, Aurore, Ollagnon, Henri-Olivier, Pacaud-Vitoux, Isabelle, Pagnier, Anne, Paris, Caroline, Parrot, Antoine, Pascart, Tristan, Pascaud-Mansour, Yasmina, Paulin, Lætitia, Pavy, Stephan, Perard, Laurent, Pers, Yves-Marie, Pha, Micheline, Pichon, Maud, Pierreisnard, Audrey, Pizana, Gabrielle, Poignant, Sylvaine, Poix, Elsa, Portier, Agnès, Poulet, Antoine, Plassard, Samira, Pugnet, Grégory, Puyraimond-Zemmour, Déborah, Quartier-Dit-Maire, Pierre, Quenet, Marion, Queyrel, Viviane, Raffray, Loïc, Remy, Philippe, Renard, Myriam, Rene, Jessica, Revuz, Sabine, Rey, Bénédicte, Richard-Colmant, Gaëlle, Riviere, Etienne, Riviere, Sébastien, Robin, Sophie, Rohmer, Julien, Roitg, Isabelle, Romier, Mélanie, Rolland, Michel, Roriz, Mélanie, Rosenberg, Carole, Rossi, Linda, Roth, Olivier, Rouidi, Sid-Ahmed, Roumier, Mathilde, Rousiere, Mickaël, Rousselin, Clémentine, Rouviere, Bénédicte, Roux, Christian, Roux, Fabienne, Roux, Marielle, Roux, Nicolas, Rouzaud, Diane, Rozenberg, Sylvie, Sacco, Isabelle, Sadji, Fatiha, Sailler, Laurent, Salliot, Carine, Salmon, Jean-Hugues, Saraux, Alain, Schmidt, Jean, Seguier, Julie, Sellam, Jérémie, Senbel, Eric, Sene, Thomas, Senet, Patricia, Seve, Pascal, Sicaud, Aurélie, Smets, Perrine, Sobanski, Vincent, Sordet, Christelle, Sornay-Rendu, Elisabeth, Souchaud-Debouverie, Odile, Sparsa, Lætitia, Spielmann, Lionel, Steib, Sarah, Stavris, Chloé, Straus, Catherine, Strotz, Victor, Szafors, Paulina, Taffignon-Clave, Séverine, Simoens, Justine, Theillac, Claire, Tenenbaum, Nora, Thomachot, Benoît, Tieulie, Nathalie, Tiriau, Soizic, Tison, Alice, Toussirot, Eric, Trefond, Ludovic, Trijau, Sophie, Trouillier, Sébastien, Trouvin, Anne-Priscille, Truchetet, Marie-Elise, Ulrich, Marc, Vaquier, Jacques, Veillard, Eric, Veillon, Laurent, Vial, Guillaume, Viallard, Jean-François, Victor, Judith, Vidon, Claire, Vidon, Mathias, Vigne, Camille, Virone, Alexandre, Warzocha, Ursula, Wendling, Daniel, Werle, Claude, Wibaux, Cécile, Willems, Alexandra, Wisniewski, Michel, Woessner, Juliette, Xerri-Campano, Bernadette, Avouac, Jérôme, Hachulla, Eric, Seror, Raphaèle, Georgin-Lavialle, Sophie, El Mahou, Soumaya, Pertuiset, Edouard, Pham, Thao, Marotte, Hubert, Servettaz, Amélie, Domont, Fanny, Chazerain, Pascal, Devaux, Mathilde, Claudepierre, Pascal, Langlois, Vincent, Mekinian, Arsène, Maria, Alexandre Thibault Jacques, Banneville, Béatrice, Fautrel, Bruno, Pouchot, Jacques, Thomas, Thierry, Flipo, René-Marc, and Richez, Christophe
Published: 2021
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8. The Impact of Immediate Initiation of Antiretroviral Therapy on Patients' Healthcare Expenditures: A Stepped-Wedge Randomized Trial in Eswatini

Author: Steinert, Janina I., Khan, Shaukat, Mafara, Emma, Wong, Cebele, Mlambo, Khudzie, Hettema, Anita, Walsh, Fiona J., Lejeune, Charlotte, Mazibuko, Sikhathele, Okello, Velephi, Ogbuoji, Osondu, De Neve, Jan-Walter, Vollmer, Sebastian, Bärnighausen, Till, and Geldsetzer, Pascal
Published: 2021
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9. Early access to antiretroviral therapy versus standard of care among HIV-positive participants in Eswatini in the public health sector: the MaxART stepped-wedge randomized controlled trial

Author: Khan, Shaukat, Spiegelman, Donna, Walsh, Fiona, Mazibuko, Sikhatele, Pasipamire, Munyaradzi, Chai, Boyang, Reis, Ria, Mlambo, Khudzie, Delva, Wim, Khumalo, Gavin, Zwane, Mandisa, Fleming, Yvette, Mafara, Emma, Hettema, Anita, Lejeune, Charlotte, Chao, Ariel, Barnighausen, Till, and Okello, Velephi
Subjects: Drug therapy, Usage, Patient outcomes, Methods, HIV infections -- Drug therapy -- Patient outcomes, Antiretroviral agents -- Usage -- Patient outcomes, Health services administration -- Methods
Abstract: 1 | INTRODUCTION In 2018, nearly 38 million people were living with human immunodeficiency virus (HIV), of whom 20.64 million live in sub-Saharan Africa. There has been a 56% decline [...], Introduction: The WHO recommends antiretroviral treatment (ART) for all HIV-positive patients regardless of CD4 count or disease stage, referred to as "Early Access to ART for All" (EAAA). The health systems effects of EAAA implementation are unknown. This trial was implemented in a government-managed public health system with the aim to examine the "real world" impact of EAAA on care retention and viral suppression. Methods: In this stepped-wedge randomized controlled trial, 14 public sector health facilities in Eswatini were paired and randomly assigned to stepwise transition from standard of care (SoC) to EAAA. ART-naive participants [greater than or equal to]18 years who were not pregnant or breastfeeding were eligible for enrolment. We used Cox proportional hazard models with censoring at clinic transition to estimate the effects of EAAA on retention in care and retention and viral suppression combined. Results: Between September 2014 and August 2017, 3405 participants were enrolled. In SoC and EAAA respectively, 12-month HIV care retention rates were 80% (95% Cl: 77 to 83) and 86% (95% CI: 83 to 88). The 12-month combined retention and viral suppression endpoint rates were 44% (95% Cl: 40 to 48) under SoC compared to 80% (95% CI: 77 to 83) under EAAA. EAAA increased both retention (HR: 1x60, 95% Cl: 1x15 to 2x21, p = 0.005) and retention and viral suppression combined (HR: 4.88, 95% Cl: 2.96 to 8.05, p < 0.001). We also identified significant gaps in current health systems ability to provide viral load (VL) monitoring with 80% participants in SoC and 66% in EAAA having a missing VL at last contact. Conclusions: The observed improvement in retention in care and on the combined retention and viral suppression provides an important co-benefit of EAAA to HIV-positive adults themselves, at least in the short term. Our results from this "rea world" health systems trial strongly support EAAA for Eswatini and countries with similar HIV epidemics and health systems. VL monitoring needs to be scaled up for appropriate care management. Keywords: universal treatment; HIV retention; viral suppression; Eswatini; Sub-Saharan Africa; antiretroviral therapy Additional information may be found under the Supporting Information tab for this article.
Published: 2020
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10. Long-term neurocognitive, psychosocial, and physical outcomes after prenatal exposure to radiotherapy: a multicentre cohort study of the International Network on Cancer, Infertility, and Pregnancy

Author: MS Medische Oncologie, Cancer, PMC Medisch specialisten, Speerpunt, Zorg en O&O, Child Health, Van Assche, Indra A, Van Calsteren, Kristel, Lemiere, Jurgen, Hohmann, Jana, Blommaert, Jeroen, Huis In 't Veld, Evangeline A, Cardonick, Elyce, LeJeune, Charlotte, Ottevanger, Nelleke P B, Witteveen, Els P O, van Grotel, Martine, van den Heuvel-Eibrink, Marry M, Lagae, Lieven, Lambrecht, Maarten, Amant, Frédéric, MS Medische Oncologie, Cancer, PMC Medisch specialisten, Speerpunt, Zorg en O&O, Child Health, Van Assche, Indra A, Van Calsteren, Kristel, Lemiere, Jurgen, Hohmann, Jana, Blommaert, Jeroen, Huis In 't Veld, Evangeline A, Cardonick, Elyce, LeJeune, Charlotte, Ottevanger, Nelleke P B, Witteveen, Els P O, van Grotel, Martine, van den Heuvel-Eibrink, Marry M, Lagae, Lieven, Lambrecht, Maarten, and Amant, Frédéric
Published: 2024

11. Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini

Author: Walsh, Fiona, Khan, Shaukat, Bärnighausen, Till, Hettema, Anita, Lejeune, Charlotte, Mazibuko, Sikhathele, Mlambo, Charmaine Khudzie, Reis, Ria, Fleming, Yvette, Khumalo, Gavin, Zwane, Mandisa, Okello, Velephi, and Spiegelman, Donna
Published: 2020
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12. m-PIMA™ HIV1/2 VL: a suitable tool for HIV-1 and HIV-2 viral load quantification in West Africa

Author: Diop-Ndiaye, Halimatou, primary, Sène, Pauline Yacine, additional, Coulibaly, Khadidiatou, additional, Diallo, Marième, additional, Diallo, Sada, additional, Diop, Karim, additional, Sow-Ndoye, Aissatou, additional, Fall, Mengue, additional, Ndiaye, Anna Julienne Selbe, additional, Mathebula, Evans, additional, Ba, Adjratou Aissatou, additional, Lejeune, Charlotte, additional, Manga, Ndeye Marie Pascaline, additional, Camara, Makhtar, additional, Ndour, Cheikh Tidiane, additional, and Kane, Coumba Toure, additional
Published: 2023
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13. #506 Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment

Author: Struys, Ilana, primary, Velázquez, Carolina, additional, Ubels, Joske, additional, Leeuwen, Anaïs Van, additional, Ghosh, Manosij, additional, Geurts, Jarne, additional, Lejeune, Charlotte, additional, Calsteren, Kristel Van, additional, Godderis, Lode, additional, Voet, Thierry, additional, Boxtel, Ruben Van, additional, Lenaerts, Liesbeth, additional, and Amant, Frédéric, additional
Published: 2023
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14. Impact of immediate initiation of antiretroviral therapy on HIV patient satisfaction

Author: Ogbuoji, Osondu, Geldsetzer, Pascal, Wong, Cebele, Khan, Shaukat, Mafara, Emma, Lejeune, Charlotte, Walsh, Fiona, Okello, Velephi, and Bärnighausen, Till
Published: 2020
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15. Preference for injectable over oral HIV pre-exposure prophylaxis in public-sector primary-care clinics in Swaziland

Author: Siedner, Mark J., Hettema, Anita, Hughey, Allison, Oldenburg, Catherine E., Kohler, Stefan, Bärnighausen, Kate, McMahon, Shannon, Jia, Chuan, Lejeune, Charlotte, Matse, Sindy, and Bärnighausen, Till
Published: 2018
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16. ‘This is mine, this is for me’: preexposure prophylaxis as a source of resilience among women in Eswatini

Author: Bärnighausen, Kate E., Matse, Sindy, Kennedy, Caitlin E., Lejeune, Charlotte L., Hughey, Allison B., Hettema, Anita, Bärnighausen, Till W., and McMahon, Shannon A.
Published: 2019
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17. Identification of misdiagnosed HIV clients in an Early Access to ART for All implementation study in Swaziland

Author: Khan, Shaukat, Mafara, Emma, Pasipamire, Munyaradzi, Spiegelman, Donna, Mazibuko, Sikhathele, Ntshalintshali, Nombuso, Hettema, Anita, Lejeune, Charlotte, Walsh, Fiona, and Okello, Velephi
Subjects: World Health Organization -- Standards, Diagnosis, Standards, Care and treatment, Usage, Analysis, Research, Dosage and administration, Highly active antiretroviral therapy -- Analysis -- Usage, HIV tests -- Analysis -- Usage, HIV -- Analysis -- Diagnosis -- Research -- Care and treatment, Antiretroviral agents -- Analysis -- Dosage and administration
Abstract: Introduction: Rapid diagnostic testing has made HIV diagnosis and subsequent treatment more accessible. However, multiple factors, including improper implementation of testing strategies and clerical errors, have been reported to lead [...]
Published: 2017
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18. Performance of Xpert HIV-1 viral load test in Senegal: a country of high circulation of CRF02_AG

Author: Séne, Pauline Yacine, primary, Diop-Ndiaye, Halimatou, additional, Ndoye, Aissatou Sow, additional, Kiernan, Brianan, additional, Coulibaly, Khadidiatou, additional, Ndiaye, Ousseynou, additional, Diallo, Sada, additional, Selbe Ndiaye, Anna Julienne, additional, Fall, Mengue, additional, Ba, Adjiratou Aissatou, additional, Camara, Makhtar, additional, Bouh Boye, Cheikh Saad, additional, Ngom, Ndeye Fatou, additional, Lejeune, Charlotte, additional, Ndour, Cheikh Tidiane, additional, and Kane, Coumba Toure, additional
Published: 2022
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19. Validation of the point of care (POC) technologies Xpert HIV-1 Qual and m-PIMA HIV 1/2 detect for early diagnosis of HIV-1 and HIV-2 in Senegal

Author: Ndoye, Aissatou Sow, primary, Ndiaye, Halimatou Diop, additional, Diallo, Marième, additional, Diack, Aminata, additional, Coulibaly, Khadydiatou, additional, Lo, Gora, additional, Kiernan, Brianan, additional, Sène, Pauline Yassine, additional, Ndiaye, Ousseynou, additional, Ngom, Ndèye Fatou, additional, Fall, Mengue, additional, Diop, Karim, additional, Gueye, Sokhna Bousso, additional, Dieng, Assane, additional, Lejeune, Charlotte, additional, Ndour, Cheikh Tidiane, additional, and Kane, Coumba Toure, additional
Published: 2022
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20. SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

Author: Leandro R. D. Sanz, Charlène Aubinet, Helena Cassol, Olivier Bodart, Sarah Wannez, Estelle A. C. Bonin, Alice Barra, Nicolas Lejeune, Charlotte Martial, Camille Chatelle, Didier Ledoux, Steven Laureys, Aurore Thibaut, Olivia Gosseries
Published: 2021
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21. Longitudinal analysis of client appointment adherence under Universal Test and Treat strategy: A stepped‐wedge trial

Author: Boeke, Caroline E., primary, Khan, Shaukat, additional, Walsh, Fiona J., additional, Lejeune, Charlotte, additional, Hettema, Anita, additional, Spiegelman, Donna, additional, Okello, Velephi, additional, and Bärnighausen, Till, additional
Published: 2021
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22. COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

Author: Avouac, Jérôme, primary, Drumez, Elodie, additional, Hachulla, Eric, additional, Seror, Raphaèle, additional, Georgin-Lavialle, Sophie, additional, El Mahou, Soumaya, additional, Pertuiset, Edouard, additional, Pham, Thao, additional, Marotte, Hubert, additional, Servettaz, Amélie, additional, Domont, Fanny, additional, Chazerain, Pascal, additional, Devaux, Mathilde, additional, Claudepierre, Pascal, additional, Langlois, Vincent, additional, Mekinian, Arsène, additional, Maria, Alexandre Thibault Jacques, additional, Banneville, Béatrice, additional, Fautrel, Bruno, additional, Pouchot, Jacques, additional, Thomas, Thierry, additional, Flipo, René-Marc, additional, Richez, Christophe, additional, Aeschlimann, Florence, additional, Agard, Christian, additional, Ait-Abdallah, Nassim, additional, Albert, Jean-David, additional, Alcais, Didier, additional, Allain, Jean-Sébastien, additional, Allanore, Yannick, additional, Amador-Borreiro, Blanca, additional, Amoura, Zahir, additional, Andre, Emma, additional, Arbault, Anaïs, additional, Arlet, Jean-Benoît, additional, Arnaud, Laurent, additional, Arniaud, Denis, additional, Arty-Hue, Herliette, additional, Atlan, Lucie, additional, Audemard-Verger, Alexandra, additional, Audoin-Pajot, Christine, additional, Audren, Victor, additional, Bach-Bunner, Maxime, additional, Bacquet-Deschryver, Hélène, additional, Bader-Meunier, Brigitte, additional, Balandraud, Nathalie, additional, Balblanc, Jean-Charles, additional, Bally, Stéphane, additional, Banal, Frédéric, additional, Barbery, Pierre, additional, Barnetche, Thomas, additional, Barrelet, Audre, additional, Basch, André, additional, Baumier, Vincent, additional, Bayer, Guillaume, additional, Bayle, Sophie, additional, Beauvais, Catherine, additional, Beinat, Rudie, additional, Belin, Véronique, additional, Belkhir, Rakiba, additional, Benainous, Ruben, additional, Belot, Alexandre, additional, Benammar, Mohammed, additional, Benhamou, Mathilde, additional, Benhamou, Ygal, additional, Benmansour, Ahmed, additional, Bennet, Pascal, additional, Bernoux-Manat, Brigitte, additional, Berthet, Elise, additional, Berthoux, Emilie, additional, Bertolini, Ewa, additional, Bigot, Adrien, additional, Bisson-Vaivre, Aurélia, additional, Blaison, Gilles, additional, Bolla, Gilles, additional, Bonidan, Olivier, additional, Bonnet, Christine, additional, Borie, Raphaël, additional, Bossert, Marie, additional, Boudou, Laurence, additional, Bouhour, Françoise, additional, Bouiller, Kévin, additional, Bouldoires, Bastien, additional, Boussoualim, Karima, additional, Bouvard, Eric, additional, Brondino, Regine, additional, Buchlin, Pierre, additional, Cabantous, Laurence, additional, Cacoub, Patrice, additional, Cadiou, Simon, additional, Carteni, Maurizio, additional, Carbasse, Aurélia, additional, Castel, Brice, additional, Cathebras, Pascal, additional, Caumont, Hervé, additional, Celant, Annalisa, additional, Chaigne, Benjamin, additional, Chaillous, Benoît, additional, Champy, Romuald, additional, Charcot, Agnès, additional, Charles, Pierre, additional, Charlot-Lambrecht, Isabelle, additional, Charpin, Caroline, additional, Chatelus, Emmanuel, additional, Chaudier, Bernard, additional, Chertok, Pascale, additional, Chevalier, Xavier, additional, Chevreau, Maxime, additional, Chotard, Emilie, additional, Chu Miow Lin, Delphine, additional, Clavel, Gaëlle, additional, Clavel-Osorio, Cyril, additional, Cohen, Fleur, additional, Cohen, Gregory, additional, Colette-Cedoz, Marie-Eve, additional, Collercandy, Nived, additional, Colombey, Antoine, additional, Comarmond, Chloé, additional, Combe, Bernard, additional, Comparon, Céline, additional, Constant, Elodie, additional, Coquerelle, Pascal, additional, Corli, Justine, additional, Corre, Clémence, additional, Costedoat-Chalumeau, Nathalie, additional, Couret, Marie, additional, Courvoisier, Natacha, additional, Coury-Lucas, Fabienne, additional, Coutarel, Cécile, additional, Coutier, Fabrice, additional, Damade, Richard, additional, Daver-Malaterre, Laurence, additional, Dehimat, Sarahe, additional, Delahousse, Michel, additional, Barrois-Delattre, Emilie, additional, Denarie, Delphine, additional, Deprouw, Camille, additional, Dernis, Emanuelle, additional, Deroux, Alban, additional, Desbarbieux, Renaud, additional, Descamps, Elise, additional, Deslandre, Chantal, additional, Desmurs, Marie, additional, Despaux, Jacques, additional, Desplats, Marie, additional, Detree, Frédérick, additional, Devauchelle-Pensec, Valérie, additional, Dhote, Robin, additional, Dieude, Philippe, additional, Dieudonne, Yannick, additional, Diot, Elisabeth, additional, Direz, Guillaume, additional, Djeddi, Djamal-Dine, additional, Douvier, Sarah, additional, Drouet, Béatrice, additional, Duc, Catherine, additional, Ducornet, Angélique, additional, Dufauret-Lombard, Carine, additional, Duhamel, Alain, additional, Dumaine, Cécile, additional, Dumel, Anne-Elisabeth, additional, Dumoulin-Richez, Chantal, additional, Duquesne, Agnès, additional, Durand, Géraldine, additional, Durandin-Truffinet, Mariane, additional, Duret, Pierre-Marie, additional, Duval, Maïka, additional, Ebbo, Mikaël, additional, Ebstein, Esther, additional, Economu-Dubosc, Andra, additional, Emilie, Stéphanie, additional, Euvrard, Romain, additional, Evon, Philippe, additional, Fabre, Sylvie, additional, Fagedet, Dorothée, additional, Farhat, Meryem, additional, Fauconier, Marion, additional, Fechtenbaum, Jacques, additional, Felten, Renaud, additional, Fernandes, Fanny, additional, Ferreira-Maldent, Nicole, additional, Feurer, Elodie, additional, Fichet, Amandine, additional, Flaisler, Françoise, additional, Florens, Nans, additional, Foltz, Violaine, additional, Fontanges, Elisabeth, additional, Foret, Jennifer, additional, Fougerousse, Anne-Claire, additional, Fouque-Aubert, Anne, additional, Foutrier-Morello, Catherine, additional, Francois-Pradier, Hélène, additional, Frantzen, Léa, additional, Fritz, Pierre, additional, Froissart, Antoine, additional, Fulpin, Jean, additional, Fuzibet, Piera, additional, Gaches, Francis, additional, Gagneux-Lemoussu, Laurence, additional, Penhoat-Gahier, Mélanie, additional, Galland, Joris, additional, Gandjbakhch, Frédérique, additional, Garnier, Nicole, additional, Garraud, Thomas, additional, Garrot, Jean-François, additional, Gastaldi, Romain, additional, Gaud-Listrat, Véronique, additional, Gauthier-Prieur, Maud, additional, Georgescu, Dana, additional, Gerard, Nathalie, additional, Gervais, Elisabeth, additional, Gibert, Christelle, additional, Gibert, Eric, additional, Gill, Ghislaine, additional, Gillard, Jérôme, additional, Gilson, Mélanie, additional, Gimonnet, Pauline, additional, Giraudet-Le Quintrec, Jeanine-Sophie, additional, Giraud-Morelet, Aude, additional, Glace, Baptiste, additional, Glanowski, Camille, additional, Godeau, Bertrand, additional, Gombert, Bruno, additional, Gonnet-Gracia, Camille, additional, Goulenok, Tiphaine, additional, Goupille, Philippe, additional, Gourmelen, Olivier, additional, Govindaraju-Audouard, Sophie, additional, Grados, Franck, additional, Grall-Lerosey, Martine, additional, Grardel, Bruno, additional, Grasland, Anne, additional, Grateau, Gilles, additional, Groza, Monica, additional, Guillaud, Constance, additional, Guillaume, Séverine, additional, Guillibert, Caroline, additional, Guillot, Xavier, additional, Guilpain, Philippe, additional, Gury, Aline, additional, Guyot, Marie-Hélène, additional, Hacquard-Bouder, Cécile, additional, Havard, Marie-Noelle, additional, Hellier, Jean-Pierre, additional, Hennequin, Pascal, additional, Henriot, Basile, additional, Henry, Julien, additional, Hentgen, Véronique, additional, Hermet, Marion, additional, Herasse, Muriel, additional, Hernandez, Julie, additional, Hie, Miguel, additional, Hilliquin, Pascal, additional, Hinschberger, Olivier, additional, Hittinger-Roux, Ambre, additional, Holubar, Jan, additional, Hudry, Christophe, additional, Huguenel, Serge, additional, Jaccard, Clara, additional, Jacquemier, Jean-Michel,, additional, Jamard, Bénédicte, additional, Jan, Catherine, additional, Jean, Sylvie, additional, Jouvray, Mathieu, additional, Juge, Pierre-Antoine, additional, Juillard, Laurent, additional, Jullien, Denis, additional, Kabala, Anna, additional, Kabchou, Abdelkrim, additional, Karkowski, Ludovic, additional, Karman, Françoise, additional, Kemiche, Farid, additional, Keraen, Jérémy, additional, Kieffer, Pierre, additional, Kone-Paut, Isabelle, additional, Koreichi, Abdeldajallil, additional, Kostine, Marie, additional, La Batide Alanore, Sylvain, additional, Lafforgue, Pierre, additional, Lahalle, Sophie, additional, Lambert, Marc, additional, Lambrecht, Isabelle, additional, Lanot, Sylvain, additional, Lanteri, Aurélia, additional, Larbre, Jean-Paul, additional, Latourte, Augustin, additional, Lavigne, Christian, additional, Le Guen Guegan, Sophie, additional, Le Guenno, Guillaume,, additional, Leguy, Diane, additional, Lebrun, Agnès, additional, Ledoult, Emmanuel, additional, Legoupil, Nathalie, additional, Legrand, Erick, additional, Lejeune, Charlotte, additional, Leloire, Olivier, additional, Leroux, Christophe, additional, Leroy, Rémi, additional, Leroy-Gouix, Marie, additional, Leturcq, Tifenn, additional, Leurs, Amélie, additional, Leveque-Michaud, Céline, additional, Limbach, François-Xavier, additional, Liote, Frédéric, additional, Lohse, Anne, additional, Lozac'h, Pierre, additional, Lucas, Virginie, additional, Madelon, Aurélie, additional, Magy-Bertrand, Nadine, additional, Mahevas, Matthieu, additional, Maillard, Hélène, additional, Maillet, Thibault, additional, Malochet-Guinamand, Sandrine, additional, Mangon, Quentin, additional, Marchou-Lopez, Sylvie, additional, Margarit, Nathalie, additional, Marhadour, Thierry, additional, Mariette, Xavier, additional, Martin, Claire, additional, Mathian, Alexis, additional, Maurier, François, additional, Maury, Frédéric, additional, Mazet-Guillaume, Betty, additional, Mazouyez, Arnaud, additional, Mazyad, Hassan, additional, Mehsen-Cetre, Nadia, additional, Meinzer, Ulrich, additional, Melki, Isabelle, additional, Messer, Laurent, additional, Miceli, Corinne, additional, Michaud, Martin, additional, Michel, Catherine, additional, Michel, Matthias, additional, Michon, Mathilde, additional, Milesi-Lecat, Anne-Marie, additional, Molto, Anna, additional, Moly, Marie, additional, Moranne, Olivier, additional, Morel, Gautier, additional, Morel, Hugo, additional, Morel, Jacques, additional, Morin, Franck, additional, Moulinier, Laurence, additional, Moulis, Guillaume, additional, Moura, Bertrand, additional, Nguyen, Minh, additional, Nicolas-Vullierme, Sabine, additional, Nielly, Hubert, additional, Nocturne, Gaétane, additional, Nottez, Aurore, additional, Ollagnon, Henri-Olivier, additional, Pacaud-Vitoux, Isabelle, additional, Pagnier, Anne, additional, Paris, Caroline, additional, Parrot, Antoine, additional, Pascart, Tristan, additional, Pascaud-Mansour, Yasmina, additional, Paulin, Lætitia, additional, Pavy, Stephan, additional, Perard, Laurent, additional, Pers, Yves-Marie, additional, Pha, Micheline, additional, Pichon, Maud, additional, Pierreisnard, Audrey, additional, Pizana, Gabrielle, additional, Poignant, Sylvaine, additional, Poix, Elsa, additional, Portier, Agnès, additional, Poulet, Antoine, additional, Plassard, Samira, additional, Pugnet, Grégory, additional, Puyraimond-Zemmour, Déborah, additional, Quartier-Dit-Maire, Pierre, additional, Quenet, Marion, additional, Queyrel, Viviane, additional, Raffray, Loïc, additional, Remy, Philippe, additional, Renard, Myriam, additional, Rene, Jessica, additional, Revuz, Sabine, additional, Rey, Bénédicte, additional, Richard-Colmant, Gaëlle, additional, Riviere, Etienne, additional, Riviere, Sébastien, additional, Robin, Sophie, additional, Rohmer, Julien, additional, Roitg, Isabelle, additional, Romier, Mélanie, additional, Rolland, Michel, additional, Roriz, Mélanie, additional, Rosenberg, Carole, additional, Rossi, Linda, additional, Roth, Olivier, additional, Rouidi, Sid-Ahmed, additional, Roumier, Mathilde, additional, Rousiere, Mickaël, additional, Rousselin, Clémentine, additional, Rouviere, Bénédicte, additional, Roux, Christian, additional, Roux, Fabienne, additional, Roux, Marielle, additional, Roux, Nicolas, additional, Rouzaud, Diane, additional, Rozenberg, Sylvie, additional, Sacco, Isabelle, additional, Sadji, Fatiha, additional, Sailler, Laurent, additional, Salliot, Carine, additional, Salmon, Jean-Hugues, additional, Saraux, Alain, additional, Schmidt, Jean, additional, Seguier, Julie, additional, Sellam, Jérémie, additional, Senbel, Eric, additional, Sene, Thomas, additional, Senet, Patricia, additional, Seve, Pascal, additional, Sicaud, Aurélie, additional, Smets, Perrine, additional, Sobanski, Vincent, additional, Sordet, Christelle, additional, Sornay-Rendu, Elisabeth, additional, Souchaud-Debouverie, Odile, additional, Sparsa, Lætitia, additional, Spielmann, Lionel, additional, Steib, Sarah, additional, Stavris, Chloé, additional, Straus, Catherine, additional, Strotz, Victor, additional, Szafors, Paulina, additional, Taffignon-Clave, Séverine, additional, Simoens, Justine, additional, Theillac, Claire, additional, Tenenbaum, Nora, additional, Thomachot, Benoît, additional, Tieulie, Nathalie, additional, Tiriau, Soizic, additional, Tison, Alice, additional, Toussirot, Eric, additional, Trefond, Ludovic, additional, Trijau, Sophie, additional, Trouillier, Sébastien, additional, Trouvin, Anne-Priscille, additional, Truchetet, Marie-Elise, additional, Ulrich, Marc, additional, Vaquier, Jacques, additional, Veillard, Eric, additional, Veillon, Laurent, additional, Vial, Guillaume, additional, Viallard, Jean-François, additional, Victor, Judith, additional, Vidon, Claire, additional, Vidon, Mathias, additional, Vigne, Camille, additional, Virone, Alexandre, additional, Warzocha, Ursula, additional, Wendling, Daniel, additional, Werle, Claude, additional, Wibaux, Cécile, additional, Willems, Alexandra, additional, Wisniewski, Michel, additional, Woessner, Juliette, additional, and Xerri-Campano, Bernadette, additional
Published: 2021
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23. Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients

Author: Victor Judith, Devaux Mathilde, Corre Clémence, Morin Franck, Ebstein Esther, Desmurs Marie, Juillard Laurent, Descamps Elise, Galland Joris, Gahier Penhoat Mélanie, Hellier Jean-Pierre, Mariette Xavier, Poix Elsa, Hudry Christophe, Constant Elodie, Trijau Sophie, Moranne Olivier, Diot Elisabeth, Hie Miguel, Guilpain Philippe, Boussoualim Karima, Mathian Alexis, Pouchot Jacques, Rohmer Julien, Senet Patricia, Michaud Martin, Tieulie Nathalie, Liote Frédéric, Ducornet Angélique, Couret Marie, Revuz Sabine, Morel Hugo, Moly Marie, Direz Guillaume, Milesi-Lecat Anne-Marie, Meinzer Ulrich, Bader-Meunier Brigitte, Steib Sarah, Gauthier-Prieur Maud, Bertolini Ewa, Gombert Bruno, Dumel Anne-Elisabeth, Henriot Basile, Froissart Antoine, Smets Perrine, Robin Sophie, Rousselin Clémentine, Moulinier Laurence, Mazet-Guillaume Betty, Brondino Regine, Malochet-Guinamand Sandrine, Balandraud Nathalie, Gibert Christelle, Godeau Bertrand, Aeschlimann Florence, Bonnet Christine, Plassard Samira, Lebrun Agnès, Mehsen-Cetre Nadia, Arlet Jean-Benoît, Gagneux-Lemoussu Laurence, Kemiche Farid, Michon Mathilde, Szafors Paulina, Werle Claude, Guillaud Constance, La Batide Alanore Sylvain, Borie Raphaël, Chazerain Pascal, Puyraimond-Zemmour Déborah, Barrelet Audre, Bach-Bunner Maxime, Flaisler Françoise, Euvrard Romain, Evon Philippe, Feurer Elodie, Gerard Nathalie, Gervais Elisabeth, Sordet Christelle, Bally Stéphane, Mazouyez Arnaud Angers, Guillot Xavier, Comarmond Chloé, Leloire Olivier, Fauconier Marion, Bouhour Françoise, Woessner Juliette, Jaccard Clara, Langlois Vincent, Sicaud Aurélie, Rolland Michel, Kabala Anna, Atlan Lucie, Amador-Borreiro Blanca, Jan Catherine, Leturcq Tifenn, Gonnet-Gracia Camille, Lanot Sylvain, Hachulla Eric, Bonidan Olivier, Domont Fanny, Dumaine Cécile, Bouiller Kévin, Senbel Eric, Comparon Céline, Huguenel Serge, Despaux Jacques, Roth Olivier, Berthoux Emilie, Dehimat Sarahe, Costedoat-Chalumeau Nathalie, Bayer Guillaume, Melki Isabelle, Toussirot Eric, Buchlin Pierre, Baumier Vincent, Charcot Agnès, Durand Géraldine, Garraud Thomas, Richez Christophe, Gillard Jérôme, Chaigne Benjamin, Rousiere Mickaël, Le Guen Guegan Sophie, Chertok Pascale, Lucas Virginie, Sadji Fatiha, Garnier Nicole, Sailler Laurent, Garrot Jean-François, Taffignon-Clave Séverine, Charles Pierre, Bernoux-Manat Brigitte, Salliot Carine, Fechtenbaum Jacques, Quenet Marion, Le Guenno Guillaume, Lanteri Aurélia, Hermet Marion, Delahousse Michel, Basch André, Grateau Gilles, Chevalier Xavier, Nocturne Gaétane, Schmidt Jean, Pacaud-Vitoux Isabelle, Roumier Mathilde, Rozenberg Sylvie, Veillard Eric, Roux Nicolas, Marhadour Thierry, Colette-Cedoz Marie-Eve, Cohen Gregory, Foltz Violaine, Fouque-Aubert Anne, Havard Marie-Noelle, Molto Anna, Chevreau Maxime, Strotz Victor, Allanore Yannick, Grardel Bruno, Francois-Pradier Hélène, Devauchelle-Pensec Valérie, Hennequin Pascal, Warzocha Ursula, Collercandy Nived, Bayle Sophie, Audren Victor, Virone Alexandre, Bennet Pascal, Grados Franck, Charpin Caroline, Fuzibet Piera, Albert Jean-David, Larbre Jean-Paul, Coutarel Cécile, Nicolas-Vullierme Sabine, Gastaldi Romain, Guyot Marie-Hélène, Georgescu Dana, Clavel Gaëlle, Tison Alice, Viallard Jean-François, Maria Alexandre, Glanowski Camille, Leroux Christophe, Vidon Mathias, Banal Frédéric, Fulpin Jean, Chotard Emilie, Gaud-Listrat Véronique, Jean Sylvie, Seguier Julie, Jacquemier Jean-Michel, Chatelus Emmanuel, Djeddi Djamal-Dine, Contamine-Sur-Arve Mazyad Hassan, Georgin-Lavialle Sophie, Belot Alexandre, Seve Pascal, Willems Alexandra, Moulis Guillaume, Latourte Augustin, Roux Marielle, Bolla Gilles, Renard Myriam, Xerri-Campano Bernadette, Bisson-Vaivre Aurélia, Fichet Amandine, Dufauret-Lombard Carine, Nielly Hubert, Ledoult Emmanuel, Alcais Didier, Giraudet-Le Quintrec Jeanine-Sophie, Wendling Daniel, Govindaraju-Audouard Sophie, Claudepierre Pascal, Fritz Pierre, Fougerousse Anne-Claire, Marotte Hubert, Fabre Sylvie, Banneville Béatrice, Quartier-Dit-Maire Pierre, Juge Pierre-Antoine, Moura Bertrand, Maillet Thibault, Messer Laurent, Thomachot Benoît, Giraud-Morelet Aude, Sparsa Lætitia, Kabchou Abdelkrim, Grasland Anne, Maurier François, Belin Véronique, Grenoble Gimonnet Pauline, Balblanc Jean-Charles, Andre Emma, Veillard Ericveillard Marie-Eliseeric, Chu Miow Lin, Pugnet Grégory, Wisniewski Michel, Carbasse Aurélia, Rene Jessica, Economu-Dubosc Andra, Bouldoires Bastien, Glace Baptiste, Benhamou Mathilde, Legoupil Nathalie, Morel Jacques, Castel Brice, Lafforgue Pierre, Carteni Maurizio, Lohse Anne, Detree Frédérick, Celant Annalisa, Trefond Ludovic, Maillard Hélène, Remy Philippe, Barnetche Thomas, Servettaz Amélie, Vigne Camille, Ferreira-Maldent Nicole, Mangon Quentin, Keraen Jérémy, Fautrel Bruno, Frantzen Léa, Legrand Erick, Sellam Jérémie, Tenenbaum Nora, Sene Thomas, Duc Catherine, Bouvard Eric, Dieudonne Yannick, Ollagnon Henri-Olivier, Deslandre Chantal, Gury Aline, Desplats Marie, Karman Françoise, Drouet Béatrice, Vidon Claire, Kone-Paut Isabelle, Groza Monica, Jamard Bénédicte, Parrot Antoine, Vial Guillaume, Ebbo Mikaël, Ait-Abdallah Nassim, Veillon Laurent, Roriz Mélanie, Chaillous Benoît, Rouidi Sid-Ahmed, Sobanski Vincent, Poulet Antoine, Clavel-Osorio Cyril, Nguyen Minh, Felten Renaud, Goulenok Tiphaine, Audoin-Pajot Christine, Foret Jennifer, Arniaud Denis, Benammar Mohammed, Boudou Laurence, Pascaud-Mansour Yasmina, Pavy Stephan, Sornay-Rendu Elisabeth, Pascart Tristan, Madelon Aurélie, Koreichi Abdeldajallil, Flipo René-Marc, El Mahou Soumaya, Benmansour Ahmed, Arty-Hue Herliette, Pers Yves-Marie, Hittinger-Roux Ambre, Sacco Isabelle, Fernandes Fanny, Gandjbakhch Frédérique, Maury Frédéric, Hacquard-Bouder Cécile, Foutrier-Morello Catherine, Rossi Linda, Belkhir Rakiba, Riviere Etienne, Drumez Elodie, Avouac Jérôme, Benainous Ruben, Champy Romuald, Florens Nans, Pichon Maud, Gibert Eric, Benhamou Ygal, Portier Agnès, Riviere Sébastien, Pham Thao, Blaison Gilles, Colombey Antoine, Marchou-Lopez Sylvie, Roux Fabienne, Leroy Rémi, Lejeune Charlotte, Bacquet-Deschryver Hélène, Romier Mélanie, Simoens Justine, Caumont Hervé, Arnaud Laurent, Paulin Lætitia, Duret Pierre-Marie, Dieude Philippe, Coury-Lucas Fabienne, Pha Micheline, Herasse Muriel, Mahevas Matthieu, Roitg Isabelle, Karkowski Ludovic, Dhote Robin, Chaudier Bernard, Gourmelen Olivier, Trouillier Sébastien, Henry Julien, Daver-Malaterre Laurence, Cathebras Pascal, Goupille Philippe, Seror Raphaële, Thomas Thierry, Pertuiset Edouard, Amoura Zahir, Richard-Colmant Gaëlle, Souchaud-Debouverie Odile, Lahalle Sophie, Jouvray Mathieu, Hentgen Véronique, Courvoisier Natacha, Charlot-Lambrecht Isabelle, Damade Richard, Argenteuil Pizana Gabrielle, Fontanges Elisabeth, Morel Gautier, Roux Christian, Perard Laurent, Gaches Francis, Cacoub Patrice, Mekinian Arsène, Cohen Fleur, Margarit Nathalie, Salmon Jean-Hugues, Guillaume Séverine, Gilson Mélanie, Coutier Fabrice, Rouzaud Diane, Duhamel Alain, Combe Bernard, Jullien Denis, Gill Ghislaine, Service d'immuno-hématologie pédiatrique [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Pontchaillou [Rennes], Service de rhumatologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Hôpital Saint-Joseph [Marseille], UNIROUEN - UFR Santé (UNIROUEN UFR Santé), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Université Paris Cité - UFR Médecine Paris Centre [Santé] (UPCité Médecine Paris Centre), Université Paris Cité (UPCité), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), CHU Necker - Enfants Malades [AP-HP], CH Belfort-Montbéliard, Service de néphrologie - dialyse [Centre hospitalier Métropole Savoie - Chambéry], Centre Hospitalier Métropole Savoie [Chambéry], Hôpital d'Instruction des Armées Begin, Service de Santé des Armées, Service de Rhumatologie [CHU Pitié Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Bordeaux [Bordeaux], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Hôpital Avicenne [AP-HP], Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service de rééducation et de réadaptation de l'appareil locomoteur et des pathologies du rachis [CHU Cochin], CHU Rouen, Normandie Université (NU), Centre hospitalier Saint Joseph - Saint Luc [Lyon], Médecine interne [Hôpitaux civils de Colmar], Hôpitaux Civils de Colmar, Institut national de recherches archéologiques préventives (Inrap), Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL], Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de Département de médecine interne et immunologie clinique [CHU Pitié-Salpêtrière] (DMIIC), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre Hospitalier Universitaire de Saint-Etienne (CHU de Saint-Etienne), Hôpital Cochin [AP-HP], PSA Peugeot Citroën (PSA), Centre Hospitalier Universitaire de Reims (CHU Reims), Service de rhumatologie [Strasbourg], CHU Strasbourg-Hôpital de Hautepierre [Strasbourg], Hôpital d'Instruction des Armées Laveran, Service de rhumatologie [Groupe Hospitalier Diaconesses Croix Saint Simon], Groupe Hospitalier Diaconesses Croix Saint-Simon, Service de rhumatologie [CHU Henri Mondor], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor, Université Grenoble Alpes - UFR Médecine (UGA UFRM), Université Grenoble Alpes (UGA), Université Paris Descartes - Faculté de Médecine (UPD5 Médecine), Université Paris Descartes - Paris 5 (UPD5), Epidemiology in Dermatology and Evaluation in Therapeutics (EpiDermE), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Fondation Ophtalmologique Adolphe de Rotschild, Service de Médecine Intensive et Réanimation [Tours], Service de médecine interne [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Département de Rhumatologie[Montpellier], Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Lapeyronie, Centre d'Etudes Lasers Intenses et Applications (CELIA), Université de Bordeaux (UB)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), AGROCAMPUS OUEST, Hôpital Foch [Suresnes], Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CHRU Brest - Service de Rhumatologie (CHU - BREST - Rhumato), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service de Médecine Interne [CHI Poissy-Saint-Germain], Centre Hospitalier Intercommunal de Poissy-Saint Germain-en-Laye (CHI Poissy-Saint Germain-en-Laye), Service de médecine interne [Avicenne], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Immuno-Rhumatologie Moléculaire, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Bretonneau, Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), AP-HP Hôpital universitaire Robert-Debré [Paris], Service de rhumatologie [Poitiers], Centre hospitalier universitaire de Poitiers (CHU Poitiers), Service de rhumatologie (Hôpitaux Civils de Colmar), Hôpital de la Timone [CHU - APHM] (TIMONE), Service de rhumatologie [CH Gustave Dron, Tourcoing], Centre Hospitalier Gustave Dron [Tourcoing], Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Chimie Agro-Industrielle (CAI), Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Service d'immuno-rhumatologie[Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Lapeyronie, CHU Trousseau [Tours], Physiopathologie, diagnostic et traitements des maladies osseuses / Pathophysiology, Diagnosis & Treatments of Bone Diseases (LYOS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de rhumatologie[Lille], Hôpital Roger Salengro [Lille]-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Centre Hospitalier de Dax, Centre Hospitalier Intercommunal de Créteil (CHIC), Hôpital Joseph Ducuing - Varsovie [Toulouse] (HJD), Hôpitaux Privés de Metz (HPMetz), Service de rhumatologie [Nantes], Université de Nantes (UN)-Hôtel-Dieu-Centre hospitalier universitaire de Nantes (CHU Nantes), Service de Médecine Interne = Hôpital de jour de médecine [CHU Tenon], Centre de Recherche en Transplantation et Immunologie (U1064 Inserm - CRTI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN), Service de médecine interne [Centre hospitalier Lons le Saunier], Centre hospitalier Lons le Saunier, Service de Rhumatologie [CHU de Grenoble], Hôpital Sud de Grenoble, Centre d'Investigation Clinique Henri Mondor (CIC Henri Mondor), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hopital saint louis (LA ROCHELLE - Hôpital Saint Louis), CH La Rochelle, Service de Médecine Interne [AP-HP, CHU Beaujon], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Beaujon [AP-HP], CHU Trousseau [APHP], CHU Amiens-Picardie, Hôpital Louis Mourier - AP-HP [Colombes], Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Langues et civilisations à tradition orale (LACITO), Université Sorbonne Nouvelle - Paris 3-Institut National des Langues et Civilisations Orientales (Inalco)-Centre National de la Recherche Scientifique (CNRS), Études Pharmaco-Immunologie (EPI), Université de La Réunion (UR), Institute for Translational Research in Inflammation - U 1286 (INFINITE (Ex-Liric)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Assistance publique-Hôpitaux de Paris - Espace éthique (AP-HP Espace éthique), Centre de Référence des Maladies Auto-Inflammatoires et des Amyloses [CH Versailles] (CeRéMAIA - Hôpital André Mignot), Centre Hospitalier de Versailles André Mignot (CHV), Physiopathologie et thérapie du muscle strié, Université Pierre et Marie Curie - Paris 6 (UPMC)-IFR14-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Maison Blanche, CHU Toulouse [Toulouse], Département de Pédiatrie [Rennes] = Paediatrics [Rennes], Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Club Rhumatismes et Inflammation, Service de Rhumatologie [CHU Bicêtre], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bicêtre, Arthrites autoimmunes (AA), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Intercommunal Alençon-Mamers (CHICAM), Service de Médecine interne [CH Antibes Juan-Les-Pins], Centre Hospitalier d’Antibes Juan-les-Pins (CH Antibes Juan-Les-Pins), Centre de référence des rhumatismes inflammatoires et maladies auto-immunes systémiques rares de l’enfant / National Referee Centre for Rheumatic and AutoImmune and Systemic Diseases in Children [Lyon] (RAISE), Biologie de l'Os et du Cartilage : Régulations et Ciblages Thérapeutiques (BIOSCAR (UMR_S_1132 / U1132)), CHU Clermont-Ferrand, Université de Lille, Groupe d'Études Remodelage Osseux et bioMatériaux (GEROM), Université d'Angers (UA), Centre Hospitalier Victor Jousselin de Dreux, Hôpital Lariboisière-Fernand-Widal [APHP], Centre Hospitalier de Belfort (Service de Rhumatologie), Oncology, Regional Hospital of Orleans, IMRB - 'Transfusion et Maladies du Globule Rouge' [Créteil] (U955 Inserm - UPEC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Service de médecine interne et immunologie clinique (SOC 1) [CHU de Dijon], Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), CHU Gabriel Montpied [Clermont-Ferrand], Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Center for Immunology of Viral Infections and Autoimmune Diseases, Le Kremlin Bicêtre, INSERM U1059, SAINBIOSE - Santé, Ingénierie, Biologie, Saint-Etienne (SAINBIOSE-ENSMSE), Centre Ingénierie et Santé (CIS-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de rhumatologie, CHU Saint-Etienne, Paediatrics, Paediatric Internal Medicine, Rheumatology and Infectious Diseases [Paris], Centre de référence des rhumatismes inflammatoires et maladies autoimmunes systémiques rares de l'enfant [Paris] (RAISE), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP Hôpital universitaire Robert-Debré [Paris], Service de rhumatologie [CHU Saint-Antoine], CHU Saint-Antoine [AP-HP], Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Service de Rhumatologie [CHRU Montpellier], Intergroupe Francophone de Cancérologie Thoracique [Paris] (IFCT), Intergroupe Francophone de Cancérologie thoracique, Histoire, Archéologie et Littératures des mondes chrétiens et musulmans médiévaux (CIHAM), École normale supérieure - Lyon (ENS Lyon)-Université Lumière - Lyon 2 (UL2)-École des hautes études en sciences sociales (EHESS)-Université Jean Moulin - Lyon 3 (UJML), Université de Lyon-Université de Lyon-Avignon Université (AU)-Centre National de la Recherche Scientifique (CNRS), Centre d'investigation clinique de Toulouse (CIC 1436), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Consultation Marfan, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Bichat, Columbia University Irving Medical Center (CUIMC), Immunologie des Maladies Virales et Autoimmunes (IMVA - U1184), Université Paris-Sud - Paris 11 (UP11)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Rhumatologie, Assistance Publique - Hôpitaux de Marseille (APHM)-Institut du Mouvement et de l'appareil Locomoteur (IML), Service d'Anesthésie réanimation [CHU Tenon], Marrow Adiposity & Bone Lab - Adiposité Médullaire et Os - ULR 4490 (MABLab (ex-pmoi)), Université du Littoral Côte d'Opale (ULCO)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHU Le Kremlin-Bicêtre (Rheumatology Department), Department of Rheumatology, Hopital Réné Dubos, Laboratoire d'Economie de Dauphine (LEDa), Université Paris Dauphine-PSL, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de médecine interne - hôpital européen Georges-Pompidou, Aix Marseille Université (AMU), Sorbonne Université (SU), Laboratoire des Maladies Neurodégénératives - UMR 9199 (LMN), Service MIRCEN (MIRCEN), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Université de Lorraine (UL), Hôpital de la Croix-Rousse [CHU - HCL], Hospices Civils de Lyon (HCL), Composantes innées de la réponse immunitaire et différenciation (CIRID), Université Bordeaux Segalen - Bordeaux 2-Centre National de la Recherche Scientifique (CNRS), Université Catholique de Louvain = Catholic University of Louvain (UCL), Université de La Réunion - Faculté de Lettres et Sciences humaines (UR FLSH), Centre de Référence National des Syndromes Hyperéosinophiliques (CEREO), Service de Médecine Interne [Hôpital Foch, Suresnes] (SMI), Equipe 3: EREN- Equipe de Recherche en Epidémiologie Nutritionnelle (CRESS - U1153), Université Sorbonne Paris Nord-Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Grenoble Alpes - École supérieure du professorat et de l'éducation - Académie de Grenoble (UGA ESPE Grenoble), Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Groupe ENergie Electrique et SYStémique (LAPLACE-GENESYS), LAboratoire PLasma et Conversion d'Energie (LAPLACE), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Service de Maladies Infectieuses et Tropicales [CHU Pitié-Salpêtrière], Epidémiologie et analyses en santé publique : risques, maladies chroniques et handicaps (LEASP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional d'Orléans (CHRO), Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Cabinet Médical de Rhumatologie, Marseille, Fondation Ophtalmologique Adolphe de Rothschild [Paris], Service de dermatologie et allergologie [CHU Tenon], Immunologie des maladies virales, auto-immunes, hématologiques et bactériennes (IMVA-HB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Service de Médecine Interne [CHU Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Centre Hospitalier de Mulhouse (Service de Rhumatologie), Centre Hospitalier Emile Muller [Mulhouse] (CH E.Muller Mulhouse), Groupe Hospitalier de Territoire Haute Alsace (GHTHA)-Groupe Hospitalier de Territoire Haute Alsace (GHTHA), Thèses d'exercice et mémoires - UFR de Médecine Montpellier-Nîmes, Université de Montpellier (UM), Centre Hospitalier Universitaire de Nice (CHU Nice), FHU 'Integrated center for research in inflammatory diseases - InCREASe', Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté]), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Hôpital Saint-André, Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases, Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Bordeaux (UB), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Université de Paris - UFR Médecine Paris Centre [Santé] (UP Médecine Paris Centre), Université de Paris (UP), Service de rhumatologie [CHU Pitié Salpêtrière] (GRC-08 EEMOIS), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Institut National de la Santé et de la Recherche Médicale (INSERM)-École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de médecine interne et d'immunologie clinique [CHU Pitié-Salpêtrière], Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Bordeaux (UB), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre National de la Recherche Scientifique (CNRS)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Joseph Ducuing, Service de Médecine Interne [CHU Tenon], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Tenon [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire Navier (NAVIER UMR 8205), École des Ponts ParisTech (ENPC)-Centre National de la Recherche Scientifique (CNRS)-Université Gustave Eiffel, Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre National de la Recherche Scientifique (CNRS)-Service MIRCEN (MIRCEN), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Service des maladies infectieuses et tropicales [CHU Pitié-Salpêtrière], Centre de Recherche Saint-Antoine (CR Saint-Antoine), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Saint-Antoine [AP-HP], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté])-Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER-Université Bourgogne Franche-Comté [COMUE] (UBFC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), UFR Médecine [Santé] - Université Paris Cité (UFR Médecine UPCité), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E), Ecole nationale supérieure des ingénieurs en arts chimiques et technologiques (ENSIACET), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Maladies génétiques d'expression pédiatrique (U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau [APHP], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Santé Ingénierie Biologie Saint-Etienne (SAINBIOSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), UNICANCER-UNICANCER-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS BFC), Université Paris Cité - UFR Médecine [Santé] (UPCité UFR Médecine), Université Paris Cité - UFR Médecine Paris Centre [Santé] (UPC Médecine Paris Centre), Université Paris Cité (UPC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPC), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université (HESAM)-HESAM Université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille, Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-IFR10, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Institut de Biologie François JACOB (JACOB), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
Subjects: Male, [SDV]Life Sciences [q-bio], communicable diseases, Disease, Logistic regression, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, law.invention, 0302 clinical medicine, law, Adrenal Cortex Hormones, Epidemiology, Immunology and Allergy, Medicine, 030212 general & internal medicine, 2. Zero hunger, education.field_of_study, glucocorticoids, Mortality rate, tumor necrosis factors, Intensive care unit, 3. Good health, Hospitalization, Autoinflammatory Disorders, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, biological therapy, Cohort, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Hypertension, Female, Adult, medicine.medical_specialty, Immunology, Population, imported, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Rheumatology, Internal medicine, Rheumatic Diseases, Humans, autoimmune diseases, Obesity, education, 030203 arthritis & rheumatology, business.industry, SARS-CoV-2, COVID-19, business, Body mass index
Abstract: ObjectivesThere is little known about the impact of SARS-CoV-2 on patients with inflammatory rheumatic and musculoskeletal diseases (iRMD). We examined epidemiological characteristics associated with severe disease, then with death. We also compared mortality between patients hospitalised for COVID-19 with and without iRMD.MethodsIndividuals with suspected iRMD-COVID-19 were included in this French cohort. Logistic regression models adjusted for age and sex were used to estimate adjusted ORs and 95% CIs of severe COVID-19. The most significant clinically relevant factors were analysed by multivariable penalised logistic regression models, using a forward selection method. The death rate of hospitalised patients with iRMD-COVID-19 (moderate–severe) was compared with a subset of patients with non-iRMD-COVID-19 from a French hospital matched for age, sex, and comorbidities.ResultsOf 694 adults, 438 (63%) developed mild (not hospitalised), 169 (24%) moderate (hospitalised out of the intensive care unit (ICU) and 87 (13%) severe (patients in ICU/deceased) disease. In multivariable imputed analyses, the variables associated with severe infection were age (OR=1.08, 95% CI: 1.05–1.10), female gender (OR=0.45, 95% CI: 0.25–0.80), body mass index (OR=1.07, 95% CI: 1.02–1.12), hypertension (OR=1.86, 95% CI: 1.01–3.42), and use of corticosteroids (OR=1.97, 95% CI: 1.09–3.54), mycophenolate mofetil (OR=6.6, 95% CI: 1.47–29.62) and rituximab (OR=4.21, 95% CI: 1.61–10.98). Fifty-eight patients died (8% (total) and 23% (hospitalised)). Compared with 175 matched hospitalised patients with non-iRMD-COVID-19, the OR of mortality associated with hospitalised patients with iRMD-COVID-19 was 1.45 (95% CI: 0.87–2.42) (n=175 each group).ConclusionsIn the French RMD COVID-19 cohort, as already identified in the general population, older age, male gender, obesity, and hypertension were found to be associated with severe COVID-19. Patients with iRMD on corticosteroids, but not methotrexate, or tumour necrosis factor alpha and interleukin-6 inhibitors, should be considered as more likely to develop severe COVID-19. Unlike common comorbidities such as obesity, and cardiovascular or lung diseases, the risk of death is not significantly increased in patients with iRMD.Trial registration numberClinicalTrials.gov Registry (NCT04353609).
Published: 2020
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24. A stepped-wedge randomised trial on the impact of early ART initiation on HIV-patients’ economic outcomes in Eswatini

Author: Steinert, Janina Isabel, primary, Khan, Shaukat, additional, Mlambo, Khudzie, additional, Walsh, Fiona J, additional, Mafara, Emma, additional, Lejeune, Charlotte, additional, Wong, Cebele, additional, Hettema, Anita, additional, Ogbuoji, Osondu, additional, Vollmer, Sebastian, additional, De Neve, Jan-Walter, additional, Mazibuko, Sikhathele, additional, Okello, Velephi, additional, Bärnighausen, Till, additional, and Geldsetzer, Pascal, additional
Published: 2020
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25. Author response: A stepped-wedge randomised trial on the impact of early ART initiation on HIV-patients’ economic outcomes in Eswatini

Author: Steinert, Janina Isabel, primary, Khan, Shaukat, additional, Mlambo, Khudzie, additional, Walsh, Fiona J, additional, Mafara, Emma, additional, Lejeune, Charlotte, additional, Wong, Cebele, additional, Hettema, Anita, additional, Ogbuoji, Osondu, additional, Vollmer, Sebastian, additional, De Neve, Jan-Walter, additional, Mazibuko, Sikhathele, additional, Okello, Velephi, additional, Bärnighausen, Till, additional, and Geldsetzer, Pascal, additional
Published: 2020
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26. Additional file 1: of Impact of early initiation versus national standard of care of antiretroviral therapy in Swazilandâ s public sector health system: study protocol for a stepped-wedge randomized trial

Author: Walsh, Fiona, BĂ¤Rnighausen, Till, Delva, Wim, Fleming, Yvette, Khumalo, Gavin, Lejeune, Charlotte, Sikhathele Mazibuko, Mlambo, Charmaine, Reis, Ria, Spiegelman, Donna, Mandisa Zwane, and Velephi Okello
Abstract: SPIRIT Checklist MaxART Trial. SPIRIT checklist for the MaxART EAAA Trial, indicating which manuscript page contains each element of the study protocol. (DOCX 53Â kb)
Published: 2017
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27. Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland's public sector health system: study protocol for a stepped-wedge randomized trial.

Author: Walsh, Fiona, Bärnighausen, Till, Delva, Wim, Fleming, Yvette, Khumalo, Gavin, Lejeune, Charlotte, Mazibuko, Sikhathele, Mlambo, Charmaine, Reis, Ria, Spiegelman, Donna, Zwane, Mandisa, Okello, Velephi, Walsh, Fiona J, Bärnighausen, Till, Lejeune, Charlotte L, and Mlambo, Charmaine Khudzie
Subjects: ANTIRETROVIRAL agents, PUBLIC health, EPIDEMICS, COMMUNICABLE diseases, DISEASE management, GOVERNMENT policy, DIAGNOSIS of HIV infections, TUBERCULOSIS microbiology, EARLY medical intervention, COMPARATIVE studies, COST effectiveness, DRUG resistance in microorganisms, DRUGS, DRUG administration, EXPERIMENTAL design, HIV infections, RESEARCH methodology, MEDICAL care costs, MEDICAL cooperation, RESEARCH protocols, OPPORTUNISTIC infections, PATIENT compliance, PATIENT satisfaction, RESEARCH, TIME, PILOT projects, PUBLIC sector, VIRAL load, EVALUATION research, RANDOMIZED controlled trials, TREATMENT effectiveness, ECONOMICS
Abstract: Background: There is robust clinical evidence to support offering early access to antiretroviral treatment (ART) to all HIV-positive individuals, irrespective of disease stage, to both improve patient health outcomes and reduce HIV incidence. However, as the global treatment guidelines shift to meet this evidence, it is still largely unknown if early access to ART for all (also referred to as "treatment as prevention" or "universal test and treat") is a feasible intervention in the resource-limited countries where this approach could have the biggest impact on the course of the HIV epidemics. The MaxART Early Access to ART for All (EAAA) implementation study was designed to determine the feasibility, acceptability, clinical outcomes, affordability, and scalability of offering early antiretroviral treatment to all HIV-positive individuals in Swaziland's public sector health system.Methods: This is a three-year stepped-wedge randomized design with open enrollment for all adults aged 18 years and older across 14 government-managed health facilities in Swaziland's Hhohho Region. Primary endpoints are retention and viral suppression. Secondary endpoints include ART initiation, adherence, drug resistance, tuberculosis, HIV disease progression, patient satisfaction, and cost per patient per year. Sites are grouped to transition two at a time from the control (standard of care) to intervention (EAAA) stage at each four-month step. This design will result in approximately one half of the total observation time to accrue in the intervention arm and the other half in the control arm. Our estimated enrolment number, which is supported by conservative power calculations, is 4501 patients over the course of the 36-month study period. A multidisciplinary, mixed-methods approach will be adopted to supplement the randomized controlled trial and meet the study aims. Additional study components include implementation science, social science, economic evaluation, and predictive HIV incidence modeling.Discussion: A stepped-wedge randomized design is a causally strong and robust approach to determine if providing antiretroviral treatment for all HIV-positive individuals is a feasible intervention in a resource-limited, public sector health system. We expect our study results to contribute to health policy decisions related to the HIV response in Swaziland and other countries in sub-Saharan Africa.Trial Registration: ClinicalTrials.gov, NCT02909218 . Registered on 10 July 2016. [ABSTRACT FROM AUTHOR]
Published: 2017
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28. La chasse à l'hippopotame d'Amenemhat, intendant du vizir Ouser. Lecture sémiologique de la scène

Author: Lejeune, Charlotte, primary
Published: 2005
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29. Prenatal exposure to chemotherapy increases the mutation burden in human neonatal hematopoietic stem cells.

Author: Struys I, Velázquez C, Ubels J, LeJeune CL, van Roosmalen MJ, Rosendahl Huber AKM, van Leeuwen AJCN, Bossuyt W, Thienpont B, Voet T, Van Calsteren K, Lenaerts L, van Boxtel R, and Amant F
Abstract: Chemotherapy is included in the standard of care for cancer treatment during pregnancy. However, whether prenatal exposure to maternal chemotherapy treatment has a mutagenic impact on the fetal genome, remains unexplored. Therefore, we investigated mutation accumulation in hematopoietic stem and progenitor cells (HSPCs) from neonates born to pregnant cancer patients treated with chemotherapy, as well as healthy pregnant women and untreated pregnant cancer patients. The mutational burden in HSPCs from neonates born to untreated pregnant cancer patients and to healthy controls was similar, but increased after prenatal exposure to varying types of chemotherapy regimens. Mutational signature analyses attributed the excess mutations to clock-like processes, which are active during normal cellular aging, or to direct mutagenesis by platinum-based drugs in neonates prenatally exposed to platinum-containing regimens. Our findings in the neonatal hematopoietic compartment are consistent with mutational signatures previously identified in cells of cancer survivors directly exposed to these chemotherapeutic drugs.
Published: 2025
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29 results on '"LeJeune Charlotte"'

1. Pushing the boundaries. Concurrent Hodgkin lymphoma and breast cancer treatment with preservation of pregnancy: A case report

2. Epithelial ovarian cancer and borderline tumors during pregnancy: a report from the International Network on Cancer, Infertility, and Pregnancy

3. Child outcomes after prenatal exposure to platinum and taxane-based chemotherapy: an unplanned interim analysis of the international network on cancer, infertility, and pregnancy study

4. Long-term neurocognitive, psychosocial, and physical outcomes after prenatal exposure to radiotherapy: a multicentre cohort study of the International Network on Cancer, Infertility, and Pregnancy

5. m-PIMA™ HIV1/2 VL: A suitable tool for HIV-1 and HIV-2 viral load quantification in West Africa

6. Successful cervical cancer treatment during a monochorionic diamniotic twin pregnancy in a patient with history of preterm delivery

7. COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

8. The Impact of Immediate Initiation of Antiretroviral Therapy on Patients' Healthcare Expenditures: A Stepped-Wedge Randomized Trial in Eswatini

9. Early access to antiretroviral therapy versus standard of care among HIV-positive participants in Eswatini in the public health sector: the MaxART stepped-wedge randomized controlled trial

10. Long-term neurocognitive, psychosocial, and physical outcomes after prenatal exposure to radiotherapy: a multicentre cohort study of the International Network on Cancer, Infertility, and Pregnancy

11. Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini

12. m-PIMA™ HIV1/2 VL: a suitable tool for HIV-1 and HIV-2 viral load quantification in West Africa

13. #506 Chemotherapy during pregnancy is associated with increased genotoxicity and mutational load in the fetal hematopoietic compartment

14. Impact of immediate initiation of antiretroviral therapy on HIV patient satisfaction

15. Preference for injectable over oral HIV pre-exposure prophylaxis in public-sector primary-care clinics in Swaziland

16. ‘This is mine, this is for me’: preexposure prophylaxis as a source of resilience among women in Eswatini

17. Identification of misdiagnosed HIV clients in an Early Access to ART for All implementation study in Swaziland

18. Performance of Xpert HIV-1 viral load test in Senegal: a country of high circulation of CRF02_AG

19. Validation of the point of care (POC) technologies Xpert HIV-1 Qual and m-PIMA HIV 1/2 detect for early diagnosis of HIV-1 and HIV-2 in Senegal

20. SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

21. Longitudinal analysis of client appointment adherence under Universal Test and Treat strategy: A stepped‐wedge trial

22. COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

23. Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients

24. A stepped-wedge randomised trial on the impact of early ART initiation on HIV-patients’ economic outcomes in Eswatini

25. Author response: A stepped-wedge randomised trial on the impact of early ART initiation on HIV-patients’ economic outcomes in Eswatini

26. Additional file 1: of Impact of early initiation versus national standard of care of antiretroviral therapy in Swazilandâ s public sector health system: study protocol for a stepped-wedge randomized trial

27. Impact of early initiation versus national standard of care of antiretroviral therapy in Swaziland's public sector health system: study protocol for a stepped-wedge randomized trial.

28. La chasse à l'hippopotame d'Amenemhat, intendant du vizir Ouser. Lecture sémiologique de la scène

29. Prenatal exposure to chemotherapy increases the mutation burden in human neonatal hematopoietic stem cells.

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29 results on '"LeJeune Charlotte"'

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