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Your search keyword '"LeBlanc, Jacques G."' showing total 46 results
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46 results on '"LeBlanc, Jacques G."'

5. An open and shut case for early VATS treatment of primary spontaneous pneumothorax in children

Author

Butterworth, Sonia A., Blair, Geoffrey K., LeBlanc, Jacques G., and Skarsgard, Erik D.

Subjects
Pneumothorax -- Care and treatment, Pneumothorax -- Research, Chest -- Surgery, Chest -- Usage, Chest -- Health aspects, Chest -- Research
Abstract

Background: Treatment of primary spontaneous pneumothorax (SP) involves thoracostomy tube (TT) drainage, with surgery reserved for persistent or recurrent air leaks. We hypothesized that the advent of video-assisted thoracic surgery [...]

Published
2007

15. Systolic and diastolic function in tricuspid valve atresia before the Fontan operation

Author

Sandor, George G.S., Patterson, Michael W.H., and LeBlanc, Jacques G.

Subjects
Heart valve diseases -- Physiological aspects, Heart -- Contraction, Diastole (Cardiac cycle) -- Measurement, Health
Abstract

Systolic and diastolic function were assessed at preoperative cardiac catheterization in 6 patients with classic tricuspid atresia and were compared with those in control subjects. All patients had systemic-to-pulmonary shunts. Left ventricular end-systolic and end-diastolic volumes and masses were significantly larger in the patient group; stroke volume and the ratio of volume to mass were also higher, but not significantly. Mean end-diastolic, peak systolic and end-systolic pressures were similar. Mean stress and end-systole and peak systole were significantly higher in the patient group. Operant chamber stiffness tended to be lower than normal, but was not statistically significant, and myocardial stiffness was normal for the patient group also. Indexes of systolic function were compared. The rate-corrected mean velocity of fiber shortening in the patient group was lower and its relation with stress at end-systole was variable with 4 abnormal patients. The ratio of stress and end-systole/end-systolic volume was significantly lower in patients. The duration of hospital stay did not correlate with end-diastolic volume or any parameter. Thus, this study found abnormalities of load-dependent and independent indexes of systolic function with normal diastolic function in young preoperative patients with tricuspid atresia. (Am J Cardiol 1994;73:292-297)

Published
1994

32. Influence of bidirectional superior cavopulmonary anastomosis on pulmonary arterial growth

Author

Slavik, Zdenek, primary, Webber, Steven A., additional, Lamb, Robert K., additional, Horvath, Pavel, additional, LeBlanc, Jacques G., additional, Keeton, Barry R., additional, Monro, James L., additional, Tax, Petr, additional, Tuma, Stanislav, additional, Reich, Oleg, additional, Sandor, George G.S., additional, Daubeney, Piers E.F., additional, and Salmon, Anthony P., additional

Published
1995
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39. The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction.

Author

Holmes, Anthony A., Co, Steve, Human, Derek G., LeBlanc, Jacques G., and Campbell, Andrew IM.

Subjects
RIGHT heart ventricle, PLASTIC surgery, MEDICAL records, RETROSPECTIVE studies, DESCRIPTIVE statistics, KAPLAN-Meier estimator, SURGERY
Abstract

Objectives : To report the clinical outcomes (early death, late death, and rate of reintervention) and performance of the Contegra conduit as a right ventricle outflow tract implant and to determine the risk factors for early reintervention. Methods : Forty-nine Contegra conduits were implanted between January 2002 and June 2009. Data collection was retrospective. The mean age and follow-up duration of Contegra recipients was 3.5 ± 4.6 years and 4.2 ± 2.0 years, respectively. Results : There were three deaths (two early, one late), giving a survival rate of 93.9%. The rate of conduit-related reintervention was 19.6% and was most often due to distal conduit stenosis. Age at implantation of <3 months, receipt of a conduit of 12-16 mm diameter, and a diagnosis of truncus arteriosus were each significant contributors to the rate of reintervention. Conclusion : The Contegra is a cost-effective and readily available solution. However, there is a limited range of larger calibers, which means that the homograft conduit (>22 mm) remains the first choice of implant in older children. The rates of reintervention are significantly higher with a diagnosis of truncus arteriosus, age at implantation of <3 months, and implantation of conduits sized 12-16 mm. [ABSTRACT FROM AUTHOR]

Published
2012
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45. Assessment of vocal fold mobility before and after cardiothoracic surgery in children.

Author

Carpes LF, Kozak FK, Leblanc JG, Campbell AI, Human DG, Fandino M, Ludemann JP, Moxham JP, and Fiori H

Subjects
Aorta, Thoracic surgery, British Columbia, Cautery, Child, Preschool, Ductus Arteriosus, Patent surgery, Female, Heart Arrest, Induced, Humans, Infant, Male, Multivariate Analysis, Pulmonary Artery surgery, Laryngoscopy, Thoracic Surgical Procedures adverse effects, Vocal Cord Paralysis etiology
Abstract

Objectives: To assess the incidence of vocal fold immobility (VFI) after cardiothoracic surgery in children and to determine the factors potentially associated with this outcome., Methods: Flexible laryngoscopy to assess vocal fold mobility was performed before surgery and within 72 hours after extubation in 100 pediatric patients who underwent cardiothoracic procedures. The 2 operating surgeons recorded the surgical technique and their impression of possible injury to the recurrent laryngeal nerve. The presence of laryngeal symptoms, such as stridor, hoarseness, and strength of cry, after extubation was documented., Results: Of 100 children included in this study, 8 had VFI after surgery. Univariate analyses showed that these 8 patients were younger and weighed less than the patients with normal vocal fold movement. Monopolar cautery was used in all patients with VFI. On univariate analysis, factors statistically significantly associated with VFI were circulatory arrest and dissection or ligation of the patent ductus arteriosus, left pulmonary artery, right pulmonary artery, or descending aorta. However, multivariate analyses failed to show these associations., Conclusions: The incidence of VFI after cardiothoracic surgery in our population of children was 8.0% (8 of 100). Of several factors found to be potentially associated with VFI on univariate analysis, none were significant on multivariate analysis. This may be a result of the few patients with VFI. A larger multicenter prospective study would be needed to definitively identify factors associated with the outcome of VFI.

Published
2011
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46. Na+/H+ exchange inhibition with HOE 642 improves recovery of the injured neonatal rabbit heart.

Author

Sett SS, Galanopoulos PT, Kashihara H, Talling DN, LeBlanc JG, and Tibbits GF

Subjects
Animals, Animals, Newborn, Aorta, Blood Flow Velocity, Cardiac Output drug effects, Coronary Circulation drug effects, Heart Rate drug effects, Myocardial Reperfusion Injury drug therapy, Rabbits, Sodium-Hydrogen Exchangers physiology, Guanidines pharmacology, Myocardial Reperfusion Injury physiopathology, Sodium-Hydrogen Exchangers antagonists & inhibitors, Sulfones pharmacology
Abstract

Background: The effects of inhibition of the Na+/H+ exchanger (NHE) on postischemic recovery of the injured neonatal rabbit heart were examined. The NHE may be an important mechanism for reperfusion injury in the neonate heart. The effects of two NHE inhibitors, HOE 642 (HOE) and 5-(N,N-dimethyl)-amiloride (DMA), given during hypothermic cardioplegic arrest, were evaluated., Methods: Isolated working crystalloid-perfused neonatal rabbit hearts were subjected to 10 min of normothermic ischemia to cause injury before undergoing 4 h of hypothermic (10 degrees C) cardioplegic arrest with a single dose of crystalloid solution (controls, n=21) or with the addition of 0.5 micromol/L HOE (n=24) or 30 micromol/L DMA (n=15)., Results: Hearts subjected to HOE had improved recoveries of aortic flow when compared with controls at 15 min and 30 min of reperfusion (35.7+/-1.3 mL/min versus 26.2+/-1.4 mL/min, respectively, at 15 min, P<0.0001; 36.5+/-1.5 mL/min versus 23.6+/-1.6 mL/min, respectively, at 30 min, P<0.0001) and with DMA at 30 min (36.5+/-1.5 mL/min versus 29.9+/-1.9 mL/min, P=0.0214). Cardiac output and systolic pressure were also improved at 30 min in HOE hearts versus controls (P<0.0001)., Conclusions: NHE inhibition with HOE during cardioplegic arrest resulted in improved functional recovery of injured hearts. Further studies in blood-perfused neonatal preparations are warranted.

Published
2003

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