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1. Enteral citrulline supplementation versus placebo on SOFA score on day 7 in mechanically ventilated critically ill patients: the IMMUNOCITRE randomized clinical trial

Author

Tadié, Jean-Marc, Locher, Clara, Maamar, Adel, Reignier, Jean, Asfar, Pierre, Commereuc, Morgane, Lesouhaitier, Mathieu, Gregoire, Murielle, Le Pabic, Estelle, Bendavid, Claude, Moreau, Caroline, Diehl, Jean-Luc, Gey, Alain, Tartour, Eric, Le Tulzo, Yves, Thibault, Ronan, Terzi, Nicolas, Gacouin, Arnaud, Roussel, Mikael, Delclaux, Christophe, Tarte, Karin, and Cynober, Luc

Published
2023
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2. Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial

Author

Fage, Nicolas, Demiselle, Julien, Seegers, Valérie, Merdji, Hamid, Grelon, Fabien, Mégarbane, Bruno, Anguel, Nadia, Mira, Jean-Paul, Dequin, Pierre-François, Gergaud, Soizic, Weiss, Nicolas, Legay, François, Le Tulzo, Yves, Conrad, Marie, Coudroy, Remi, Gonzalez, Frédéric, Guitton, Christophe, Tamion, Fabienne, Tonnelier, Jean-Marie, Bedos, Jean Pierre, Van Der Linden, Thierry, Vieillard-Baron, Antoine, Mariotte, Eric, Pradel, Gaël, Lesieur, Olivier, Ricard, Jean-Damien, Hervé, Fabien, Du Cheyron, Damien, Guerin, Claude, Mercat, Alain, Teboul, Jean-Louis, Radermacher, Peter, and Asfar, Pierre

Published
2022
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3. Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study

Author

Gangneux, Jean-Pierre, Dannaoui, Eric, Fekkar, Arnaud, Luyt, Charles-Edouard, Botterel, Françoise, De Prost, Nicolas, Tadié, Jean-Marc, Reizine, Florian, Houzé, Sandrine, Timsit, Jean-François, Iriart, Xavier, Riu-Poulenc, Béatrice, Sendid, Boualem, Nseir, Saad, Persat, Florence, Wallet, Florent, Le Pape, Patrice, Canet, Emmanuel, Novara, Ana, Manai, Melek, Cateau, Estelle, Thille, Arnaud W, Brun, Sophie, Cohen, Yves, Alanio, Alexandre, Mégarbane, Bruno, Cornet, Muriel, Terzi, Nicolas, Lamhaut, Lionel, Sabourin, Estelle, Desoubeaux, Guillaume, Ehrmann, Stephan, Hennequin, Christophe, Voiriot, Guillaume, Nevez, Gilles, Aubron, Cécile, Letscher-Bru, Valérie, Meziani, Ferhat, Blaize, Marion, Mayaux, Julien, Monsel, Antoine, Boquel, Frédérique, Robert-Gangneux, Florence, Le Tulzo, Yves, Seguin, Philippe, Guegan, Hélène, Autier, Brice, Lesouhaitier, Matthieu, Pelletier, Romain, Belaz, Sorya, Bonnal, Christine, Berry, Antoine, Leroy, Jordan, François, Nadine, Richard, Jean-Christophe, Paulus, Sylvie, Argaud, Laurent, Dupont, Damien, Menotti, Jean, Morio, Florent, Soulié, Marie, Schwebel, Carole, Garnaud, Cécile, Guitard, Juliette, Le Gal, Solène, Quinio, Dorothée, Morcet, Jeff, Laviolle, Bruno, Zahar, Jean-Ralph, and Bougnoux, Marie-Elisabeth

Published
2022
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4. Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial

Author

Egle, Alexander, Greil, Richard, Joannidis, Michael, Lamprecht, Bernd, Altdorfer, Antoine, Belkhir, Leila, Fraipont, Vincent, Hites, Maya, Verschelden, Gil, Aboab, Jérôme, Ader, Florence, Ait-Oufella, Hafid, Andrejak, Claire, Andreu, Pascal, Argaud, Laurent, Bani-Sadr, Firouzé, Benezit, François, Blot, Mathieu, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bouchaud, Olivier, Bougon, David, Bouiller, Kevin, Bounes-Vardon, Fanny, Boutoille, David, Boyer, Alexandre, Bruel, Cédric, Cabié, André, Canet, Emmanuel, Cazanave, Charles, Chabartier, Cyrille, Chirouze, Catherine, Clere-Jehl, Raphaël, Courjon, Johan, Crockett, Flora, Danion, François, Delbove, Agathe, Dellamonica, Jean, Djossou, Félix, Dubost, Clément, Duvignaud, Alexandre, Epaulard, Olivier, Epelboin, Loïc, Fartoukh, Murielle, Faure, Karine, Faure, Emmanuel, Ferry, Tristan, Ficko, Cécile, Figueiredo, Samy, Gaborit, Benjamin, Gaci, Rostane, Gagneux-Brunon, Amandine, Gallien, Sébastien, Garot, Denis, Geri, Guillaume, Gibot, Sébastien, Goehringer, François, Gousseff, Marie, Gruson, Didier, Hansmann, Yves, Hinschberger, Olivier, Jaureguiberry, Stéphane, Jeanmichel, Vanessa, Kerneis, Solen, Kimmoun, Antoine, Klouche, Kada, Lachâtre, Marie, Lacombe, Karine, Laine, Fabrice, Lanoix, Jean-Philippe, Launay, Odile, Laviolle, Bruno, Le Moing, Vincent, Le Pavec, Jérôme, Le Tulzo, Yves, Le Turnier, Paul, Lebeaux, David, Lefevre, Benjamin, Leroy, Sylvie, Lescure, François-Xavier, Lessire, Henry, Leveau, Benjamin, Loubet, Paul, Makinson, Alain, Malvy, Denis, Marquette, Charles-Hugo, Martin-Blondel, Guillaume, Martinot, Martin, Mayaux, Julien, Mekontso-Dessap, Armand, Meziani, Ferhat, Mira, Jean-Paul, Molina, Jean-Michel, Monnet, Xavier, Mootien, Joy, Mourvillier, Bruno, Murris-Espin, Marlène, Navellou, Jean-Christophe, Nseir, Saad, Oulehri, Walid, Peiffer-Smadja, Nathan, Perpoint, Thomas, Pialoux, Gilles, Pilmis, Benoît, Piriou, Vincent, Piroth, Lionel, Poissy, Julien, Pourcher, Valérie, Quenot, Jean-Pierre, Raffi, François, Reignier, Jean, Revest, Matthieu, Richard, Jean-Christophe, Riu-Poulenc, Béatrice, Robert, Céline, Roger, Pierre-Alexandre, Roger, Claire, Rouveix-Nordon, Elisabeth, Ruch, Yvon, Saidani, Nadia, Sayre, Naomi, Senneville, Eric, Sotto, Albert, Stefan, Francois, Tacquard, Charles, Terzi, Nicolas, Textoris, Julien, Thiery, Guillaume, Timsit, Jean-François, Tolsma, Violaine, Turmel, Jean-Marie, Valour, Florent, Wallet, Florent, Wattecamps, Guilhem, Yazdanpanah, Yazdan, Zerbib, Yoann, Berna, Marc, Reuter, Jean, Staub, Thérèse, Braz, Sandra, Ferreira Ribeiro, Joao-Miguel, Paiva, José-Artur, Roncon-Albuquerque, Roberto, Bouscambert-Duchamp, Maude, Gaymard, Alexandre, Lê, Minh-Patrick, Lina, Bruno, Peytavin, Gilles, Tubiana, Sarah, Couffin-Cadièrgues, Sandrine, Esperou, Hélène, Belhadi, Drifa, Burdet, Charles, Costagliola, Dominique, Dechanet, Aline, Delmas, Christelle, Diallo, Alpha, Fougerou, Claire, Guedj, Jérémie, Mentré, France, Mercier, Noémie, Noret, Marion, Saillard, Juliette, Velou, Priyanka, and Paiva, Jose-Artur

Published
2022
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7. SARS-CoV-2-Induced ARDS Associates with MDSC Expansion, Lymphocyte Dysfunction, and Arginine Shortage

Author

Reizine, Florian, Lesouhaitier, Mathieu, Gregoire, Murielle, Pinceaux, Kieran, Gacouin, Arnaud, Maamar, Adel, Painvin, Benoit, Camus, Christophe, Le Tulzo, Yves, Tattevin, Pierre, Revest, Matthieu, Le Bot, Audrey, Ballerie, Alice, Cador-Rousseau, Berengère, Lederlin, Mathieu, Lebouvier, Thomas, Launey, Yoann, Latour, Maelle, Verdy, Clotilde, Rossille, Delphine, Le Gallou, Simon, Dulong, Joelle, Moreau, Caroline, Bendavid, Claude, Roussel, Mikael, Cogne, Michel, Tarte, Karin, and Tadié, Jean-Marc

Published
2021
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8. Pressure-Support Ventilation vs T-Piece During Spontaneous Breathing Trials Before Extubation Among Patients at High Risk of Extubation Failure: A Post-Hoc Analysis of a Clinical Trial

Author

Boissier, Florence, Chatellier, Delphine, Deletage, Céline, Guignon, Carole, Joly, Florent, Olivry, Morgane, Veinstein, Anne, Benzekri-Lefevre, Dalila, Boulain, Thierry, Muller, Grégoire, Le Tulzo, Yves, Tadié, Jean-Marc, Maamar, Adel, Demiri, Suela, Mayaux, Julien, Decavèle, Maxens, Bouadma, Lila, Dupuis, Claire, Asfar, Pierre, Pierrot, Marc, Béduneau, Gaëtan, Boyer, Déborah, Delmas, Benjamin, Puech, Bérénice, Bachoumas, Konstantinos, Soum, Edouard, Cabasson, Séverin, Hoppe, Marie-Anne, Nseir, Saad, Pouly, Olivier, Bourdin, Gaël, Rosselli, Sylvène, Le Meur, Anthony, Garret, Charlotte, Martin, Maelle, Berquier, Guillaume, Thiagarajah, Abirami, Carteaux, Guillaume, Mekontso-Dessap, Armand, Poidevin, Antoine, Dureau, Anne-Florence, Azais, Marie-Ange, Colin, Gwenhaël, Mercier, Emmanuelle, Morisseau, Marlène, Sabatier, Caroline, Picard, Walter, Gainnier, Marc, Nguyen, Thi-My-Hue, Prat, Gwenaël, Schwebel, Carole, Buscot, Matthieu, Thille, Arnaud W., Coudroy, Rémi, Nay, Mai-Anh, Gacouin, Arnaud, Demoule, Alexandre, Sonneville, Romain, Beloncle, François, Girault, Christophe, Dangers, Laurence, Lautrette, Alexandre, Levrat, Quentin, Rouzé, Anahita, Vivier, Emmanuel, Lascarrou, Jean-Baptiste, Ricard, Jean-Damien, Razazi, Keyvan, Barberet, Guillaume, Lebert, Christine, Ehrmann, Stephan, Massri, Alexandre, Bourenne, Jeremy, Pradel, Gael, Bailly, Pierre, Terzi, Nicolas, Dellamonica, Jean, Lacave, Guillaume, Robert, René, Ragot, Stéphanie, and Frat, Jean-Pierre

Published
2020
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10. Comparison of prognostic factors between bacteraemic and non-bacteraemic critically ill immunocompetent patients in community-acquired severe pneumococcal pneumonia: a STREPTOGENE sub-study

Author

Bellut, Hugo, Porcher, Raphael, Varon, Emmanuelle, Asfar, Pierre, Le Tulzo, Yves, Megarbane, Bruno, Mathonnet, Armelle, Dugard, Anthony, Veinstein, Anne, Ouchenir, Kader, Siami, Shidasp, Reignier, Jean, Galbois, Arnaud, Cousson, Joël, Preau, Sébastien, Baldesi, Olivier, Rigaud, Jean‑Philippe, Souweine, Bertrand, Misset, Benoit, Jacobs, Frederic, Dewavrin, Florent, Mira, Jean‑Paul, and Bedos, Jean‑Pierre

Published
2021
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14. Impact of Arterial CO2Retention in Patients With Moderate or Severe ARDS

Author

Maamar, Adel, Delamaire, Flora, Reizine, Florian, Lesouhaitier, Mathieu, Painvin, Benoit, Quelven, Quentin, Coirier, Valentin, Guillot, Pauline, Le Tulzo, Yves, Tadie, Jean Marc, Gacouin, Arnaud, Centre Hospitalier Universitaire [Rennes], Université de Rennes - Faculté de Médecine (UR Médecine), Université de Rennes (UR), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), and None

Subjects
Pulmonary and Respiratory Medicine, [SDV]Life Sciences [q-bio], cohort study, ARDS, hypercapnia, General Medicine, Critical Care and Intensive Care Medicine, mortality, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract
Abstract

International audience; BACKGROUND: Lung-protective ventilation (reduced tidal volume and limited plateau pressure) may lead to CO(2) retention. Data about the impact of hypercapnia in patients with ARDS are scarce and conflicting. METHODS: We performed a non-interventional cohort study with subjects with ARDS admitted from 2006 to 2021 and with P(aO(2)) /F(IO(2)) ≤ 150 mm Hg. We examined the association between severe hypercapnia (P(aCO(2)) ≥ 50 mm Hg) on the first 5 days after the diagnosis of ARDS and death in ICU for 930 subjects. All the subjects received lung-protective ventilation. RESULTS: Severe hypercapnia was noted in 552 subjects (59%) on the first day of ARDS (day 1); 323/930 (34.7%) died in the ICU. Severe hypercapnia on day 1 was associated with mortality in the unadjusted (odds ratio 1.54, 95% CI 1.16-1.63; P = .003) and adjusted (odds ratio 1.47, 95% CI 1.08-2.43; P = .004) models. In the Bayesian analysis, the posterior probability that severe hypercapnia was associated with ICU death was > 90% in 4 different priors, including a septic prior for this association. Sustained severe hypercapnia on day 5, defined as severe hypercapnia present from day 1 to day 5, was noted in 93 subjects (12%). After propensity score matching, severe hypercapnia on day 5 remained associated with ICU mortality (odds ratio 1.73, 95% CI 1.02-2.97; P = .047). CONCLUSIONS: Severe hypercapnia was associated with mortality in subjects with ARDS who received lung-protective ventilation. Our results deserve further evaluation of the strategies and treatments that aim to control CO(2) retention.

Published
2023

15. Host-pathogen interactions and prognosis of critically ill immunocompetent patients with pneumococcal pneumonia: the nationwide prospective observational STREPTOGENE study

Author

Bedos, Jean-Pierre, Varon, Emmanuelle, Porcher, Raphael, Asfar, Pierre, Le Tulzo, Yves, Megarbane, Bruno, and Mathonnet, Armelle

Subjects
Penicillin G -- Health aspects, Bacterial pneumonia -- Prognosis -- Risk factors, Mortality -- France, Pneumonia -- Prognosis -- Risk factors, Hospital patients -- Prognosis, Septic shock -- Risk factors -- Prognosis, Health care industry
Abstract

Purpose To assess the relative importance of host and bacterial factors associated with hospital mortality in patients admitted to the intensive care unit (ICU) for pneumococcal community-acquired pneumonia (PCAP). Methods Immunocompetent Caucasian ICU patients with PCAP documented by cultures and/or pneumococcal urinary antigen (UAg Sp) test were included in this multicenter prospective study between 2008 and 2012. All pneumococcal strains were serotyped. Logistic regression analyses were performed to identify risk factors for hospital mortality. Results Of the 614 patients, 278 (45%) had septic shock, 270 (44%) had bacteremia, 307 (50%) required mechanical ventilation at admission, and 161 (26%) had a diagnosis based only on the UAg Sp test. No strains were penicillin-resistant, but 23% had decreased susceptibility. Of the 36 serotypes identified, 7 accounted for 72% of the isolates, with different distributions according to age. Although antibiotics were consistently appropriate and were started within 6 h after admission in 454 (74%) patients, 116 (18.9%) patients died. Independent predictors of hospital mortality in the adjusted analysis were platelets [less than or equal to] 100 x 10.sup.9/L (OR, 7.7; 95% CI, 2.8-21.1), McCabe score [greater than or equal to] 2 (4.58; 1.61-13), age > 65 years (2.92; 1.49-5.74), lactates > 4 mmol/L (2.41; 1.27-4.56), male gender and septic shock (2.23; 1.30-3.83 for each), invasive mechanical ventilation (1.78; 1-3.19), and bilateral pneumonia (1.59; 1.02-2.47). Women with platelets [less than or equal to] 100 x 10.sup.9/L had the highest mortality risk (adjusted OR, 7.7; 2.8-21). Conclusions In critically ill patients with PCAP, age, gender, and organ failures at ICU admission were more strongly associated with hospital mortality than were comorbidities. Neither pneumococcal serotype nor antibiotic regimen was associated with hospital mortality., Author(s): Jean-Pierre Bedos [sup.1], Emmanuelle Varon [sup.2] [sup.3], Raphael Porcher [sup.4], Pierre Asfar [sup.5], Yves Le Tulzo [sup.6], Bruno Megarbane [sup.7], Armelle Mathonnet [sup.8], Anthony Dugard [sup.9], Anne Veinstein [sup.10], [...]

Published
2018
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20. Effects of mean arterial pressure on arousal in sedated ventilated patients with septic shock: a SEPSISPAM post hoc exploratory study

Author

Jouan, Youenn, Seegers, Valérie, Meziani, Ferhat, Grelon, Fabien, Megarbane, Bruno, Anguel, Nadia, Mira, Jean-Paul, Dequin, Pierre-François, Gergaud, Soizic, Weiss, Nicolas, Legay, François, Le Tulzo, Yves, Conrad, Marie, Robert, René, Gonzalez, Frédéric, Guitton, Christophe, Tamion, Fabienne, Tonnelier, Jean-Marie, Guezennec, Pierre, Van Der Linden, Thierry, Vieillard-Baron, Antoine, Radermacher, Peter, and Asfar, Pierre

Published
2019
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21. Fiberoptic endoscopic validation of a clinical screening test of swallowing function in critically ill patients performed within 24 h after extubation

Author

Maamar, Adel, primary, Parent, Valentine, additional, Prudhomme, Emmanuelle, additional, Guérot, Emmanuel, additional, Berneau, Pauline, additional, Frérou, Aurélien, additional, Le Tulzo, Yves, additional, Jégoux, Franck, additional, Gacouin, Arnaud, additional, and Tadié, Jean-Marc, additional

Published
2022
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22. Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

Author

Bougouin, Wulfran, Marijon, Eloi, Planquette, Benjamin, Karam, Nicole, Dumas, Florence, Celermajer, David, Jost, Daniel, Lamhaut, Lionel, Beganton, Frankie, Cariou, Alain, Meyer, Guy, Jouven, Xavier, Bureau, Côme, Charpentier, Julien, Salem, Omar Ben Hadj, Guillemet, Lucie, Arnaout, Michel, Ferre, Alexis, Geri, Guillaume, Mongardon, Nicolas, Pène, Frédéric, Chiche, Jean-Daniel, Mira, Jean-Paul, Labro, Guylaine, Belon, François, Luu, Vinh-Phuc, Chenet, Julien, Besch, Guillaume, Puyraveau, Marc, Piton, Gaël, Capellier, Gilles, Martin, Maëlle, Lascarrou, Jean-Baptiste, Le Thuaut, Aurélie, Lacherade, Jean-Claude, Martin-Lefèvre, Laurent, Fiancette, Maud, Vinatier, Isabelle, Lebert, Christine, Bachoumas, Konstantinos, Yehia, Aihem, Henry-Laguarrigue, Matthieu, Colin, Gwenhaël, Reignier, Jean, Privat, Elodie, Escutnaire, Joséphine, Dumont, Cyrielle, Baert, Valentine, Vilhelm, Christian, Hubert, Hervé, Robert-Edan, Vincent, Lakhal, Karim, Quartin, Andrew, Hobbs, Brian, Cely, Cynthia, Bell, Cynthia, Pham, Tai, Schein, Roland, Geng, Yimin, Ng, Chaan, Ehrmann, Stephan, Gandonnière, Charlotte Salmon, Boisramé-Helms, Julie, Le Tilly, Olivier, De Bretagne, Isabelle Benz, Mercier, Emmanuelle, Mankikian, Julie, Bretagnol, Anne, Meziani, Ferhat, Halimi, Jean Michel, Le Guellec, Chantal Barin, Gaudry, Stéphane, Hajage, David, Tubach, Florence, Pons, Bertrand, Boulet, Eric, Boyer, Alexandre, Chevrel, Guillaume, Lerolle, Nicolas, Carpentier, Dorothée, de Prost, Nicolas, Lautrette, Alexandre, Mayaux, Julien, Nseir, Saad, Ricard, Jean-Damien, Dreyfuss, Didier, Robert, René, Garzotto, Franscesco, Kipnis, Eric, Tetta, Ciro, Ronco, Claudio, Schnell, David, Aurelie, Bourmaud, Reynaud, Marie, Clec’h, Christophe, Benyamina, Mourad, Vincent, François, Mariat, Christophe, Bornstain, Caroline, Rouleau, Stephane, Leroy, Christophe, Cohen, Yves, Morel, Jerome, Legrand, Matthieu, Terreaux, Jeremy, Darmon, Michaël, Cantier, Marie, Morisot, Adeline, Guérot, Emmanuel, Canet, Emmanuel, De Montmollin, Etienne, Voiriot, Guillaume, Neuville, Mathilde, Timsit, Jean-François, Sonneville, Romain, Fayssoil, Abdallah, Stojkovic, Tania, Behin, Anthony, Ogna, Adam, Lofaso, Frédéric, Laforet, Pascal, Wahbi, Karim, Prigent, Helene, Duboc, Denis, Orlikowski, David, Eymard, Bruno, Annane, Djillali, Le Guennec, Loic, Cholet, Clémentine, Bréchot, Nicolas, Hekimian, Guillaume, Besset, Sébastien, Lebreton, Guillaume, Nieszkowska, Ania, Trouillet, Jean Louis, Leprince, Pascal, Combes, Alain, Luyt, Charles-Edouard, Griton, Marion, Sesay, Musa, De Panthou, Nadia Sibaï, Bienvenu, Thomas, Biais, Matthieu, Nouette-Gaulain, Karine, Fossat, Guillaume, Baudin, Florian, Coulanges, Cécile, Bobet, Sabrine, Dupont, Arnaud, Courtes, Léa, Benzekri, Dalila, Kamel, Toufik, Muller, Grégoire, Bercault, Nicolas, Barbier, François, Runge, Isabelle, Skarzynski, Marie, Mathonnet, Armelle, Boulain, Thierry, Jouan, Youenn, Teixera, Noémie, Hassen-Khodja, Claire, Guillon, Antoine, Gaborit, Christophe, Grammatico-Guillon, Leslie, Rebière, Cécile, Azoulay, Elie, Misset, Benoit, Ruckly, Stephane, Garrouste-Orgeas, Maïté, Kentish-Barnes, Nancy, Duranteau, Jacques, Thuong, Marie, Joseph, Liliane, Renault, Anne, Lesieur, Olivier, Larbi, Anne-Gaelle Si, Viquesnel, Gérald, Zuber, Benjamin, Marque, Sophie, Kandelman, Stanislas, Pichon, Nicolas, Floccard, Bernard, Galon, Marion, Chevret, Sylvie, Kentish-Barnes, Nancy, Seegers, Valérie, Legriel, Stéphane, Jaber, Samir, Lefrant, Jean Yves, Reuter, Danielle, Guisset, Olivier, Cracco, Christophe, Seguin, Amélie, Durand-Gasselin, Jacques, Thirion, Marine, Cohen-Solal, Zoé, Foulgoc, Hélène, Rogier, Julien, Delobbe, Elsa, Schortgen, Frédérique, Asfar, Pierre, Julie, Boisramé-Helms, Grimaldi, David, Fabien, Grelon, Anguel, Nadia, Sigismond, Lasocki, Matthieu, Henry-Lagarrigue, Gonzalez, Frédéric, François, Legay, Guitton, Christophe, Schenck, Maleka, Jean-Marc, Doise, Radermacher, Peter, Kentish-Barnes, Nancy, Makunza, Joseph Nsiala, Nathalie, Mejeni Kamdem, Pierre, Akilimali, Adolphe, Kilembe Manzanza, Mahieu, Rafael, Reydel, Thomas, Jamet, Angéline, Chudeau, Nicolas, Huntzinger, Julien, Grange, Steven, Courte, Anne, Lemarie, Jérémie, Gibot, Sébastien, Champey, Julia, Dellamonica, Jean, Du Cheyron, Damien, Contou, Damien, Tadié, Jean-Marc, Cour, Martin, Beduneau, Gaetan, Marchalot, Antoine, Guérin, Laurent, Jochmans, Sebastien, Terzi, Nicolas, Preau, Sebastien, Brun-Buisson, Christian, Dessap, Armand Mekontso, Vedrenne-Cloquet, Meryl, Breinig, Sophie, Jung, Camille, Brussieux, Maxime, Marcoux, Marie-Odile, Durrmeyer, Xavier, Blondé, Renaud, Angoulvant, François, Grasset, Jérôme, Naudin, Jérôme, Dauger, Stéphane, Remy, Solenn, Kolev-Descamp, Karine, Demaret, Julie, Monneret, Guillaume, Javouhey, Etienne, Chomton, Maryline, Sauthier, Michaël, Vallieres, Emilie, Jouvet, Philippe, Geslain, Guillaume, Guellec, Isabelle, Rambaud, Jérôme, Schmidt, Matthieu, Schellongowski, Peter, Dorget, Amandine, Patroniti, Nicolo, Taccone, Fabio Silvio, Miranda, Dinis Reis, Reuter, Jean, Prodanovic, Hélène, Pierrot, Marc, Balik, Martin, Park, Sunghoon, Guérin, Claude, Papazian, Laurent, Jean, Reignier, Ayzac, Louis, Loundou, Anderson, Forel, Jean-Marie, Mezidi, Mehdi, Aublanc, Mylène, Perinel-Ragey, Sophie, Lissonde, Floriane, Louf-Durier, Aurore, Tapponnier, Romain, Yonis, Hodane, Coudroy, Remi, Frat, Jean-Pierre, Boissier, Florence, Thille, Arnaud W., Richard, Flore, Le Gullou-Guillemette, Hélène, Fahri, Jonathan, Kouatchet, Achille, Bodet-Contentin, Laetitia, Garot, Denis, Le Pennec, Déborah, Vecellio, Laurent, Tavernier, Elsa, Dequin, Pierre François, Messika, Jonathan, Martin, Yolaine, Maquigneau, Natacha, Puechberty, Christelle, Stoclin, Annabelle, Villard, Serge, Dechanet, Aline, De Jong, Audrey, Monnin, Marion, Girard, Mehdi, Chanques, Gérald, Molinari, Nicolas, Decavèle, Maxens, Campion, Sébastien, Ainsouya, Roukia, Niérat, Marie-Cécile, Raux, Mathieu, Similowski, Thomas, Demoule, Alexandre, Razazi, Keyvan, Tchir, Martial, May, Faten, Carteaux, Guillaume, Pauline, Rougevin-Baville, Marc, Andronikof, Bedos, Jean Pierre, Mehrsa, Koukabi, Mauger-Briche, Carole, Mijon, François, Trouiller, Pierre, Sztrymf, Benjamin, Cretallaz, Pierre, Mermillod-Blondin, Romain, Savary, Dominique, Sedghiani, Ines, Doghri, Hamdi, Jendoubi, Asma, Hamdi, Dhekra, Cherif, Mohamed Ali, Hechmi, Youssef Zied El, Zouheir, Jerbi, Persico, Nicolas, Maltese, Francois, Ferrigno, Cécile, Bablon, Amandine, Marmillot, Cécile, Roch, Antoine, Sedghiani, Ines, Papin, Grégory, Gainnier, Marc, Argaud, Laurent, Christophe, Adrie, Souweine, Bertrand, Goldgran-Toledano, Dany, Marcotte, Guillaume, Dumenil, Anne Sylvie, Carole, Schwebel, Cecchini, Jerôme, Tuffet, Samuel, Fartoukh, Muriel, Roux, Damien, Thyrault, Martial, Armand, Mekontso Dessap, Chauveau, Simon, Wesner, Nadège, Monnier-Cholley, Laurence, Bigé, Naïke, Ait-Oufella, Hafid, Guidet, Bertrand, Dubée, Vincent, Labroca, Pierre, Lemarié, Jérémie, Chiesa, Gérard, Laroyenne, Isabelle, Borrini, Léo, Klotz, Rémi, Sy, Quoc Phan, Cristina, Marie-Christine, Paysant, Jean, Fillâtre, Pierre, Gacouin, Arnaud, Revest, Matthieu, Tattevin, Pierre, Flecher, Erwan, Le Tulzo, Yves, Jamme, Matthieu, Daviaud, Fabrice, Marin, Nathalie, Thy, Michael, Duceau, Baptiste, Ardisson, Fanny, Sandrine, Valade, Venot, Marion, Schlemmer, Benoît, Zafrani, Lara, Pons, Stéphanie, Styfalova, Lenka, Bouadma, Lila, Radjou, Aguila, Lebut, Jordane, Mourvillier, Bruno, Dorent, Richard, Dilly, Marie-Pierre, Nataf, Patrick, Wolff, Michel, Le Gall, Aëlle, Bourcier, Simon, Tandjaoui-Lambiotte, Yacine, Das, Vincent, Alves, Mikael, Bigé, Naïke, Kamilia, Chtara, Rania, Ammar, Baccouch, Najeh, Turki, Olfa, Ben, Hmida Chokri, Bahloul, Mabrouk, Bouaziz, Mounir, Dupuis, Claire, Perozziello, Anne, Letheulle, Julien, Valette, Marc, Herrmann-Storck, Cécile, Crosby, Laura, Elkoun, Khalid, Madeux, Benjamin, Martino, Frédéric, Migueres, Hélène, Piednoir, Pascale, Posch, Matthias, Thiery, Guillaume, Huynh-Ky, Minh-Tu, Bouchard, Pierre Alexandre, Sarrazin, Jean-François, Lellouche, François, Nay, Mai-Anh, Lortat-Jacob, Brice, Rozec, Bertrand, Colnot, Marion, Belin, Nicolas, Barrot, Loïc, Navellou, Jean-Christophe, Patry, Cyrille, Chaignat, Claire, Claveau, Melanie, Claude, Frédéric, Aubron, Cécile, Mcquilten, Zoe, Bailey, Michael, Board, Jasmin, Buhr, Heidi, Cartwright, Bruce, Dennis, Mark, Forrest, Paul, Hodgson, Carol, Mcilroy, David, Murphy, Deirdre, Murray, Lynnette, Pellegrino, Vincent, Pilcher, David, Sheldrake, Jayne, Tran, Huyen, Vallance, Shirley, Cooper, Jamie, Bombled, Camille, Vidal, Charles, Margetis, Dimitri, Amour, Julien, Coart, Domien, Dubois, Jasperina, Van Herpe, Tom, Mesotten, Dieter, Bailly, Sébastien, Lucet, Jc, Lepape, Alain, L’hériteau, François, Aupée, Martine, Bervas, Caroline, Boussat, Sandrine, Berger-Carbonne, Anne, Machut, Anaïs, Savey, Anne, Tudesq, Jean-Jacques, Valade, Sandrine, Galicier, Lionel, De Bazelaire, Cédric, Munoz-Bongrand, Nicolas, Mignard, Xavier, Biard, Lucie, Mokart, Djamel, Nyunga, Martine, Bruneel, Fabrice, Rabbat, Antoine, Perez, Pierre, Meert, Anne Pascale, Benoit, Dominique, Mariotte, Eric, Ehooman, Franck, Hamidfar-Roy, Rebecca, Hourmant, Yannick, Mailloux, Arnaud, Beurton, Alexandra, Teboul, Jean-Louis, Girroto, Valentina, Laura, Galarza, Richard, Christian, Monnet, Xavier, Dubée, Vincent, Merdji, Hamid, Dang, Julien, Preda, Gabriel, Baudel, Jean-Luc, Desnos, Cyrielle, Zeitouni, Michel, Belaroussi, Ines, Parrot, Antoine, Blayau, Clarisse, Fulgencio, Jean-Pierre, Quesnel, Christophe, Labbe, Vincent, De Chambrun, Marc Pineton, Beloncle, François, Merceron, Sybille, Fedun, Yannick, Lecomte, Bernard, Devaquet, Jérôme, Puidupin, Marc, Verdière, Bruno, Amoura, Zahir, Vuillard, Constance, Xavier, Jais, Bourlier, Delphine, David, Amar, Caroline, Sattler, David, Montani, Gerald, Simmoneau, Olivier, Sitbon, Humbert, Marc, Laurent, Savale, Dujardin, Olivier, Bouglé, Adrien, Ait, Hamou Nora, Salem, Joe Elie, El-Helali, Najoua, Coppere, Zoé, Gibelin, Aude, Taconet, Clementine, Djibre, Michel, Maamar, Adel, Colobert, Elen, Fillatre, Pierre, Uhel, Fabrice, Camus, Christophe, Moraly, Josquin, Dahoumane, Redouane, Maury, Eric, Tan, Boun Kim, Emmanuel, Vivier, Pauline, Misslin, Laurence, Parmeland, Philippe, Poirié, Zahar, Jean-Ralph, Catherine, Haond, Christian, Pommier, Karim, Ait-Bouziad, Mounia, Hocine, Laura, Témime, Rasoldier, Vero Hanitra, Mager, Guy, Eraldi, Jean-Pierre, Gelinotte, Stéphanie, Bougerol, François, Dehay, Julien, Rigaud, Jean-Philippe, Declercq, Pierre Louis, Michel, Julien, Aissa, Nejla, Henard, Sandrine, Guerci, Philippe, Latar, Ichraq, Levy, Bruno, Girerd, Nicolas, Kimmoun, Antoine, Abdallah, Saousen Ben, Nakaa, Sabrine, Hraiech, Kmar, Braiek, Dhouha Ben, Adhieb, Ali, M’ghirbi, Abdelwaheb, Ousji, Ali, Hammouda, Zeineb, Abroug, Fekri, Sellami, Walid, Hajjej, Zied, Samoud, Walid, Labbene, Iheb, Ferjani, Mustapha, Medhioub, Fatma Kaaniche, Allela, Rania, Algia, Najla Ben, Cherif, Samar, Attia, Delphine, Herinjatovo, Andrianjafy, Francois, Xavier Laborne, Bouhouri, Med Aziz, Slaoui, Mohamed Taoufik, Soufi, A., Khaleq, K., Hamoudi, D., Nsiri, A., Harrar, R., Maury, Eric, Goursaud, Suzanne, Gauberti, Maxime, Labeyrie, Paul-Emile, Gaberel, Thomas, Agin, Véronique, Maubert, Eric, Vivien, Denis, Gakuba, Clément, Armel, Anwar, Abdou, Rchi, Kalouch, Samira, Yaqini, Khalid, Chlilek, Aziz, Sellami, Walid, Yedder, Soumaya Ben, Tonnelier, Alexandre, Hervé, Fabien, Halley, Guillaume, Frances, Jean-Luc, Moriconi, Mickael, Saoli, Mathieu, Garnero, Aude, Demory, Didier, Arnal, Jean Michel, Canoville, Bertrand, Daubin, Cédric, Brunet, Jennifer, Ghezala, Hassen Ben, Snouda, Salah, Ben, Chiekh Imen, Kaddour, Moez, Ouanes, Islem, Marzouk, Mahdi, Haniez, Françoise, Jaillet, Hélène, Maas, Henri, Andrivet, Pierre, Darné, Christian, Viau, François, Ghezala, Hassen Ben, Ouanes, Islem, Dangers, Laurence, Montlahuc, Claire, Perbet, Sébastien, Ouanes, Islem, Hamouda, Zeineb, Nakee, Sabrine, Ouanes-Besbes, Lamia, Meddeb, Khaoula, Khedher, Ahmed, Sma, Nesrine, Ayachi, Jihene, Khelfa, Messaouda, Fraj, Nesrine, Lakhal, Hend Ben, Hammed, Hedia, Boukadida, Raja, Hafsa, Hajer, Chouchene, Imed, Boussarsar, Mohamed, Ben, Braiek Dhouha, Ouanes-Besbes, Lamia, Benatti, Kaoutar, Dafir, A., Aissaoui, W., Elallame, W., Haddad, W., Cherkab, R., Elkettani, C., Barrou, L., Hamou, Zakaria Ait, Repessé, Xavier, Charron, Cyril, Aubry, Alix, Paternot, Alexis, Maizel, Julien, Slama, Michel, Vieillard-Baron, Antoine, Trifi, Ahlem, Abdellatif, Sami, Fatnassi, Meriem, Daly, Foued, Nasri, Rochdi, Ismail, Khaoula Ben, Lakhal, Salah Ben, Bazalgette, Florian, Daurat, Aurelien, Roger, Claire, Muller, Laurent, Doyen, Denis, Plattier, Rémi, Robert, Alexandre, Hyvernat, Hervé, Bernardin, Gilles, Jozwiak, Mathieu, Gimenez, Julia, Mercado, Pablo, Depret, François, Tilouch, Najla, Mater, Houda, Habiba, Ben Sik Ali, Jaoued, Oussama, Gharbi, Rim, Hassen, Mohamed Fekih, Elatrous, Souheil, Pasquier, Pierre, Vuillemin, Quentin, Schaal, Jean-Vivien, Martinez, Thibault, Duron, Sandrine, Trousselard, Marion, Schwartzbrod, Pierre-Eric, Baugnon, Thomas, Dupic, Laurent, Gout, Caroline Duracher, De Saint Blanquat, Laure, Séguret, Sylvie, Le Ficher, Gaelle, Orliaguet, Gilles, Hubert, Philippe, Bigé, Naïke, Leblanc, Guillaume, Briand, Raphael, Brousse, Lucas, Brunet, Valentine, Chatelain, Léonard, Prat, Dominique, Jacobs, Frédéric, Demars, Nadège, Hamzaoui, Olfa, Moneger, Guy, Sztrymf, Benjamin, Duburcq-Gury, Emilie, Satre-Buisson, Léa, Duburcq, Thibault, Poissy, Julien, Robriquet, Laurent, Jourdain, Merce, Sécheresse, Thierry, Miquet, Mattéo, Simond, Alexis, Usseglio, Pascal, Hamdaoui, Yamina, Boussarsar, Mohamed, Desailly, Victoire, Brun, Patrick, Iglesias, Pauline, Huet, Jérémie, Masseran, Clémence, Claudon, Antoine, Ebeyer, Clément, Truong, Thomas, Tesnière, Antoine, Mignon, Alexandre, Gaudry, Stéphane, Resiere, Dabor, Valentino, Ruddy, Fabre, Julien, Roze, Benoit, Ferge, Jean-Louis, Charbatier, Cyrille, Marie, Sabia, Scholsser, Michel, Aitsatou, Signate, Raad, Mathieu, Cabie, Andre, Mehdaoui, Hossein, Cousin, Clement, Rousseau, Christophe, Llitjos, Jean-François, Alby-Laurent, Fanny, Toubiana, Julie, Belaidouni, Nadia, Cherruault, Marlène, Tamburini, Jérome, Bouscary, Didier, Fert, Sarah, Delile, Eugénie, Besnier, Emmanuel, Coquerel, David, Nevière, Rémi, Richard, Vincent, Tamion, Fabienne, Wei, Chaojie, Louis, Huguette, Margaux, Schmitt, Eliane, Albuisson, Sophie, Orlowski, Kimmoun, Antoine, Riad, Zakaria, Coroir, Marine, Rémy, Bernard, Camille, Bombled, Joffre, Jeremie, Aegerter, Philippe, Ilic, Dejan, Ginet, Marc, Pignard, Caroline, Nguyen, Philippe, Mourey, Guillaume, Samain, Emmanuel, Pili-Floury, Sebastien, Jouffroy, Romain, Nicolas, Caill, Alvarez, Jean-Claude, Tomasso, Maraffi, Philippe, Pascal, Raphalen, Jean-Herlé, Frédéric, J. Baud, Vivien, Benoit, Pierre, Carli, Baud, Frederic, Fredj, Hana, Blel, Youssef, Brahmi, Nozha, Ghezala, Hassen Ben, Hanak, Anne-Sophie, Malissin, Isabelle, Poupon, Joel, Risede, Patricia, Chevillard, Lucie, Megarbane, Bruno, Barghouth, Manel, M’rad, Aymen, Hmida, Marwa Ben, Thabet, Hafedh, Liang, Hao, Callebert, Jacques, Lagard, Camille, Megarbane, Bruno, Habacha, Sahar, Chatbri, Bassem, Camillerapp, Christophe, Labat, Laurence, Soichot, Marion, Garçon, Pierre, Goury, Antoine, Kerdjana, Lamia, Voicu, Sebastian, Deye, Nicolas, Megarbane, Bruno, Armel, Anwar, Anas, Benqqa, Othman, Mezgui, Moumine, S., Kalouch, S., Yakini, K. K., Chlilek, A., Hajji, Ahmed, Louati, Assaad, Khaldi, Ammar, Borgi, Aida, Ghali, Nargess, Bouziri, Asma, Menif, Khaled, Ben, Jaballah Najla, Armel, Anwar, Brochon, Jeanne, Dumitrescu, Mihaela, Thévenot, Sarah, Saulnier, Jean-Pascal, Husseini, Khaled, Laland, Catherine, Cremniter, Julie, Bousseau, Anne, Castel, Olivier, Brémaud-Csizmadia, Cassandra, Diss, Margot, Portefaix, Aurélie, Berthiller, Julien, Gillet, Yves, Aoul, Nabil Tabet, Douah, Ali, Addou, Zakaria, Youbi, Houari, Moussati, Mohamed, Belhabiche, Kamel, Mir, Souad, Abada, Sanaa, Amel, Zerhouni, Aouffen, Nabil, Bouzit, Zina, Grati, Ahmed H., Dhonneur, Gilles F., Boussarsar, Mohamed, Lau, Nicolas, Mezhari, Ilham, Roucaud, Nicolas, Le Meur, Matthieu, Paulet, Rémi, Coudray, Jean-Michel, Ghomari, Wahiba Imène, Boumlik, Reda, Peigne, Vincent, Daban, Jean-Louis, Boutonnet, Mathieu, Lenoir, Bernard, Yassine, Hafiani, Mohamed, Cheikh Chaigar, Khalid, Allali, Ihssan, Moussaid, Said, Elyoussoufi, Said, Salmi, Jazia, Amira Ben, Fatima, Jaziri, Wafa, Skouri, Maha, Bennasr, Khaoula, Ben Abdelghni, Sami, Turki, Abdallah Taeib, B., Medhioub, Fatma Kaaniche, Rollet-Cohen, Virginie, Sachs, Philippe, Merchaoui, Zied, Renolleau, Sylvain, Oualha, Mehdi, Eloi, Maxime, Jean, Sandrine, Demoulin, Maryne, Valentin, Cécile, Guilbert, Julia, Walti, Hervé, Carbajal, Ricardo, Leger, Pierre-Louis, Karaca-Altintas, Yasemin, Botte, Astrid, Labreuche, Julien, Drumez, Elodie, Devos, Patrick, Bour, Franck, Leclerc, Francis, Ahmed, Ayari, khaled, Menif, Louati, Assaad, Aida, Borgi, Ammar, Khaldi, Narjess, Ghali, Ahmed, Hajji, Asma, Bouziri, Jaballah, Nejla Ben, Leger, Pierre-Louis, Pansiot, Julien, Besson, Valérie, Palmier, Bruno, Baud, Olivier, Cauli, Bruno, Charriaut-Marlangue, Christiane, Mansuy, Amélie, Michel, Fabrice, Le Bel, Stéphane, Boubnova, Julia, Ughetto, Fabrice, Ovaert, Caroline, Fouilloux, Virginie, Paut, Olivier, Jacquet-Lagrèze, Matthias, Tiebergien, Nicolas, Hanna, Najib, Evain, Jean-Noël, Baudin, Florent, Courtil-Teyssedre, Sonia, Bompard, Dominique, Lilot, Marc, Chardonal, Laurent, Fellahi, Jean-Luc, Claverie, Claire, Pouessel, Guillaume, Dorkenoo, Aimée, Renaudin, Jean-Marie, Eb, Mireille, Deschildre, Antoine, Leteurtre, Stéphane, Yassine, Hafiani, Kamal, Belkadi, Adil, Oboukhlik, Ouafa, Aalalam, Mouhamed, Moussaoui, Rachid, Charkab, Lahoucine, Barrou, Dachraoui, Fahmi, Nakkaa, Sabrine, Zaineb, Hammouda, Mlika, Dorra, Gloulou, Olfa, Boussarsar, Mohamed, Zelmat, Setti-Aouicha, Batouche, Djamila-Djahida, Chaffi, Belkacem, Mazour, Fatima, Benatta, Nadia, Fathallah, Ines, Aloui, Rafaa, Zoubli, Aymen, Kouraichi, Nadia, Fathallah, Ines, Kouraichi, N., Salem, Shireen, Vicaut, Eric, Megarbane, Bruno, Ambroise, David, Loriot, Anne-Marie, Bourgogne, Emmanuel, Megarbane, Bruno, Ghadhoune, Hatem, Jihene, Guissouma, Trabelsi, Insaf, Allouche, Hend, Brahmi, Habib, Samet, Mohamed, Ghord, Hatem El, Lebeau, Rodolphe, Laplanche, Jean-Louis, Benturquia, Nadia, Megarbane, Bruno, Blel, Youssef, M’rad, A., Essafi, Fatma, Benabderrahim, A., Jouffroy, Romain, Resiere, Dabor, Sanchez, Bruno, Inamo, Jocelyn, Megarbane, Bruno, Batouche, Djamila-Djahida, Zerhouni, Amel, Tabeliouna, Kheira, Negadi, Amine, Mentouri, Zahia, Le Gall, Fanny, Hanouz, Jean-Luc, Normand, Hervé, Khoury, Abdo, Sall, Fatimata Seydou, De Luca, Alban, Pugin, Aurore, Pazart, Lionel, Vidal, Chrystelle, Leroux, Franck, Khoury, Abdo, L’Her, Erwan, Marjanovic, Nicolas, Khoury, Abdo, Desmettre, Thibault, Lambert, Christophe, Ragey, Sophie Perinel, Baboi, Loredana, Bazin, Jean-Etienne, Koffel, Catherine, Dhonneur, Gilles, Bouzit, Zina, Bradai, Larbi, Ayed, Issam Ben, Aissa, Fethi, Haouache, Hakim, Marechal, Yoann, Biston, Patrick, Piagnerelli, Michael, Bortolotti, Perrine, Colling, Delphine, Colas, Vincent, Voisin, Benoit, Dewavrin, Florent, Onimus, Thierry, Girardie, Patrick, Saulnier, Fabienne, Urbina, Tomas, Nguyen, Yann, Druoton, Anne-Lise, Soudant, Marc, Barraud, Damien, Conrad, Marie, Cravoisy-Popovic, Aurélie, Nace, Lionel, Bollaert, Pierre-Edouard, Martin, Ruste, Bitker, Laurent, Richard, Jean-Christophe, Brossier, David, Goyer, Isabelle, Marquis, Christopher, Lampin, Marie, Duhamel, Alain, Béhal, Hélène, Dhaoui, Tahar, Godeffroy, Véronique, Devouge, Eve, Evrard, Dominique, Delepoulle, Florence, Racoussot, Sylvie, Grandbastien, Bruno, Lampin, Marie, Heilbronner, Claire, Roy, Emeline, Masson, Alexandra, Hadchouel-Duvergé, Alice, Rigourd, Virginie, Delacroix, Elise, Wroblewski, Isabelle, Pin, Isabelle, Ego, Anne, Payen, Valerie, Debillon, Thierry, Millet, Anne, Denot, Julien, Berthelot, Véronique, Thueux, Emilie, Reymond, Marie, De Larrard, Alexandra, Amblard, Alain, Leger, Pierre-Louis, Aoul, Nabil Tabet, Lemiale, Virginie, Oziel, Johanna, Brule, Noelle, Moreau, Anne-Sophie, Marhbène, Takoua, Sellami, Salma, Jamoussi, Amira, Ayed, Samia, Mhiri, Emna, Slim, Leila, Khelil, Jalila Ben, Besbes, Mohamed, Chawki, Sylvain, Hamdi, Aicha, Ciroldi, Magali, Cottereau, Alice, Obadia, Edouard, Zerbib, Yoann, Andrejak, Claire, Ricome, Sylvie, Dupont, Hervé, Baudin, François, Dureau, Pauline, Tanguy, Audrey, Arbelot, Charlotte, Ben, Hassen Kais, Charfeddine, Ahmed, Granger, Benjamin, Laporte, Lucile, Hermetet, Coralie, Regaieg, Kais, Khemakhem, Rim, Chelly, Hedi, Cheikh, Chaigar Mohammed, Mountij, Hamid, Rghioui, Kawtar, Haddad, Wafae, Cherkab, Rachid, Barrou, Houcine, Naima, Aitmouden, bennani, Othmani M., Regaieg, Kais, Douib, Ahmed, Samet, Amal, Cungi, Pierre-Julien, Nguyen, Cédric, Cotte, Jean, D’aranda, Erwan, Meaudre, Eric, Avaro, Jean-Phillipe, Slaoui, Mohamed Taoufik, Mokline, Amel, Rahmani, Imene, Laajili, Achraf, Amri, Helmi, Gharsallah, Lazheri, Gasri, Bahija, Tlaili, Sofiene, Hammouda, Rym, Messadi, Amen Allah, Sudden Death Expertise Center, AKIKI Study Group, DO-RE-MI-FA Group, ENCEPHALITICA Study Group, for the HYPER2S Investigators and REVA Research Network, for the Purpura Fulminans Study Group, GFRUP RMEF, REVA ECMOnet, REA-RAISIN Study Group, for the EurêClark Study Group, and Groupe Communication et Simulation en Pédiatrie

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2017
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23. Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

Author

Kamilia, Chtara, Regaieg, Kais, Baccouch, Najeh, Chelly, Hedi, Bahloul, Mabrouk, Bouaziz, Mounir, Jendoubi, Ali, Abbes, Ahmed, Belhaouane, Houda, Nasri, Oussama, Jenzri, Layla, Ghedira, Salma, Houissa, Mohamed, Belkadi, Kamal, Harti, Youness, Nsiri, Afak, Khaleq, Khalid, Hamoudi, Driss, Harrar, Rachid, Thieffry, Camille, Wallet, Frédéric, Parmentier-Decrucq, Erika, Favory, Raphaël, Mathieu, Daniel, Poissy, Julien, Lafon, Thomas, Vignon, Philippe, Begot, Emmanuelle, Appert, Alexandra, Hadj, Mathilde, Claverie, Paul, Matt, Morgan, Barraud, Olivier, François, Bruno, Jamoussi, Amira, Jazia, Amira Ben, Marhbène, Takoua, Lakhdhar, Dhouha, Khelil, Jalila Ben, Besbes, Mohamed, Goutay, Julien, Blazejewski, Caroline, Joly-Durand, Isabelle, Pirlet, Isabelle, Weillaert, Marie Pierre, Beague, Sebastien, Aziz, Soufi, Hafiane, Reda, Hattabi, Khalid, Bouhouri, Mohamed Aziz, Hammoudi, Driss, Fadil, Abdelaziz, Harrar, Rachid Al, Zerouali, Khalid, Medhioub, Fatma Kaaniche, Allela, Rania, Algia, Najla Ben, Cherif, Samar, Slaoui, Mohamed Taoufik, Boubia, Souhail, Hafiani, Y., Khaoudi, A., Cherkab, R., Elallam, W., Elkettani, C., Barrou, L., Ridaii, M., Mehdi, Rihi El, Schimpf, Caroline, Mizrahi, Assaf, Pilmis, Benoît, Le Monnier, Alban, Tiercelet, Kelly, Cherin, Mélanie, Bruel, Cédric, Philippart, Francois, Bailly, Sébastien, Lucet, Jc, Lepape, Alain, L’hériteau, François, Aupée, Martine, Bervas, Caroline, Boussat, Sandrine, Berger-Carbonne, Anne, Machut, Anaïs, Savey, Anne, Timsit, Jean-François, Razazi, Keyvan, Rosman, Jérémy, de Prost, Nicolas, Carteaux, Guillaume, Jansen, Chloe, Decousser, Jean Winoc, Brun-Buisson, Christian, Dessap, Armand Mekontso, M’rad, Aymen, Ouali, Zouhour, Barghouth, Manel, Kouatchet, Achille, Mahieu, Rafael, Weiss, Emmanuel, Schnell, David, Zahar, Jean-Ralph, Artiguenave, Margaux, Sophie, Paktoris-Papine, Espinasse, Florence, Sayed, Faten El, Dinh, Aurélien, Charron, Cyril, Geri, Guillaume, Vieillard-Baron, Antoine, Repessé, Xavier, Kallel, Hatem, Mayence, Claire, Houcke, Stéphanie, Guegueniat, Pascal, Hommel, Didier, Dhifaoui, Kaouther, Hajjej, Zied, Fatnassi, Amira, Sellami, Walid, Labbene, Iheb, Ferjani, Mustapha, Dachraoui, Fahmi, Nakkaa, Sabrine, M’ghirbi, Abdelwaheb, Adhieb, Ali, Braiek, Dhouha Ben, Hraiech, Kmar, Ousji, Ali, Ouanes, Islem, Zaineb, Hammouda, Abdallah, Saousen Ben, Ouanes-Besbes, Lamia, Abroug, Fekri, Klein, Simon, Miquet, Mattéo, Thouret, Jean-Marc, Peigne, Vincent, Daban, Jean-Louis, Boutonnet, Mathieu, Lenoir, Bernard, Merhbene, Takoua, Derreumaux, Celine, Seguin, Thierry, Conil, Jean-Marie, Kelway, Charlotte, Blasco, Valery, Nafati, Cyril, Harti, Karim, Reydellet, Laurent, Albanese, Jacques, Aicha, Narjess Ben, Meddeb, Khaoula, Khedher, Ahmed, Ayachi, Jihene, Fraj, Nesrine, Sma, Nesrine, Chouchene, Imed, Boussarsar, Mohamed, Yedder, Soumaya Ben, Samoud, Walid, Radhouene, Bousselmi, Mariem, Bousselmi, Ammar, Asma, Cheikh, Asma Ben, Lakhal, Hend Ben, Khelfa, Messaouda, Hamdaoui, Yamina, Bouafia, Nabiha, Trampont, Timothée, Daix, Thomas, Legarçon, Vincent, Karam, Henri Hani, Pichon, Nicolas, Essafi, Fatma, Foudhaili, Nasreddine, Thabet, Hafedh, Blel, Youssef, Brahmi, Nozha, Ezzouine, Hanane, Kerrous, Mahmoud, Haoui, Saad El, Ahdil, Soufiane, Benslama, Abdellatif, Abidi, Khalid, Dendane, Tarek, Oussama, Ssouni, Belayachi, Jihane, Madani, Naoufal, Abouqal, Redouane, Zeggwagh, Amine Ali, Ghadhoune, Hatem, Chaari, Anis, Jihene, Guissouma, Allouche, Hend, Trabelsi, Insaf, Brahmi, Habib, Samet, Mohamed, Ghord, Hatem El, Habiba, Ben Sik Ali, Hajer, Nouira, Tilouch, Najla, Yaakoubi, Sondes, Jaoued, Oussama, Gharbi, Rim, Hassen, Mohamed Fekih, Elatrous, Souheil, Arcizet, Julien, Leroy, Bertrand, Abdulmalack, Caroline, Renzullo, Catherine, Hamet, Maël, Doise, Jean-Marc, Coutet, Jérôme, Cheikh, Chaigar Mohammed, Quechar, Zakaria, Joris, Magalie, Beauport, Dimitri Titeca, Kontar, Loay, Lebon, Delphine, Gruson, Bérengère, Slama, Michel, Marolleau, Jean-Pierre, Maizel, Julien, Gorham, Julie, Ameye, Lieveke, Berghmans, Thierry, Paesmans, Marianne, Sculier, Jean-Paul, Meert, Anne-Pascale, Guillot, Max, Ledoux, Marie-Pierre, Braun, Thierry, Maestraggi, Quentin, Michard, Baptiste, Castelain, Vincent, Herbrecht, Raoul, Schneider, Francis, Couffin, Severine, Lobo, David, Mongardon, Nicolas, Dhonneur, Gilles, Mounier, Roman, Le Borgne, Pierrick, Couraud, Sophie, Herbrecht, Jean-Etienne, Boivin, Alexandra, Lefebvre, François, Bilbault, Pascal, Zelmat, Setti-Aouicha, Batouche, Djamila-Djahida, Mazour, Fatima, Chaffi, Belkacem, Benatta, Nadia, Sik, Ali Habiba, Talik, I., Perrier, Maxime, Gouteix, Eliane, Koubi, Claude, Escavy, Annabelle, Guilbaut, Victoria, Fosse, Jean-Philippe, Jazia, Rahma Ben, Abdelghani, Ahmed, Cungi, Pierre-Julien, Bordes, Julien, Nguyen, Cédric, Pierrou, Candice, Cruc, Maximilien, Benois, Alain, Duprez, Frédéric, Bonus, Thierry, Cuvelier, Grégory, Ollieuz, Sandra, Machayekhi, Sharam, Paciorkowski, Frédéric, Reychler, Gregory, Coudroy, Remi, Thille, Arnaud W., Drouot, Xavier, Diaz, Véronique, Meurice, Jean-Claude, Robert, René, Turki, Olfa, Ben, Hmida Chokri, Assefi, Mona, Deransy, Romain, Brisson, Hélène, Monsel, Antoine, Conti, Filomena, Scatton, Olivier, Langeron, Olivier, Ghezala, Hassen Ben, Snouda, Salah, Ben, Chiekh Imen, Kaddour, Moez, Armel, Anwar, Youness, Lafrikh, Abdelhak, Bensaid, Youssef, Miloudi, Najib, Al Harrar, Mustapha, Amouzoun, Noufel, Mtioui, Mohamed, Zamd, Salma, El Khayat, Ghizlane, Medkouri, Mohamed, Benghanam, Benyounes, Ramdani, Montini, Florent, Moschietto, Sébastien, Gregoire, Emilien, Claisse, Guillaume, Guiot, Julien, Morimont, Philippe, Krzesinski, Jean-Marie, Mariat, Christophe, Lambermont, Bernard, Cavalier, Etienne, Delanaye, Pierre, Benbernou, Soumia, Ilies, Sofiane, Azza, Abdelkader, Bouyacoub, Khalida, Louail, Meriem, Mokhtari-Djebli, Houria, Arrestier, Romain, Daviaud, Fabrice, Francois, Xavier Laborne, Brocas, Elsa, Choukroun, Gérald, Peñuelas, Oscar, Lorente, José-Angel, Cardinal-Fernandez, Pablo, Rodriguez, José-Maria, Aramburu, José-Antonio, Esteban, Andres, Frutos-Vivar, Fernando, Bitker, Laurent, Costes, Nicolas, Le Bars, Didier, Lavenne, Franck, Devouassoux, Mojgan, Richard, Jean-Christophe, Mechati, Malika, Gainnier, Marc, Papazian, Laurent, Guervilly, Christophe, Garnero, Aude, Arnal, Jean Michel, Roze, Hadrien, Richard, Jean Christophe, Repusseau, Benjamin, Dewitte, Antoine, Joannes-Boyau, Olivier, Ouattara, Alexandre, Harbouze, Nadia, Amine, A. M., Olandzobo, A. G., Herbland, Alexandre, Richard, Marie, Girard, Nicolas, Lambron, Lucile, Lesieur, Olivier, Wainschtein, Sarah, Hubert, Sidonie, Hugues, Albane, Tran, Marc, Bouillard, Philippe, Loteanu, Vlad, Leloup, Maxime, Laurent, Alexandra, Lheureux, Florent, Prestifilippo, Alessia, Cruz, Martin Delgado Maria, Romain, Rigal, Antonelli, Massimo, Blanch, Torra Lluis, Bonnetain, Franck, Grazzia-Bocci, Maria, Mancebo, Jordi, Samain, Emmanuel, Paul, Hebert, Capellier, Gilles, Zavgorodniaia, Taissa, Soichot, Marion, Malissin, Isabelle, Voicu, Sebastian, Garçon, Pierre, Goury, Antoine, Kerdjana, Lamia, Deye, Nicolas, Bourgogne, Emmanuel, Megarbane, Bruno, Mejri, Olfa, Hmida, Marwa Ben, Tannous, Salma, Chevillard, Lucie, Labat, Laurence, Risede, Patricia, Fredj, Hana, Léger, Maxime, Brunet, Marion, Le Roux, Gaël, Boels, David, Lerolle, Nicolas, Farah, Souaad, Amiel-Niemann, Hélène, Kubis, Nathalie, Declèves, Xavier, Peyraux, Nicoals, Baud, Frederic, Serafini, Micaela, Alvarez, Jean-Claude, Heinzelman, Annette, Jozwiak, Mathieu, Millasseau, Sandrine, Teboul, Jean-Louis, Alphonsine, Jean-Emmanuel, Depret, François, Richard, Nathalie, Attal, Pierre, Richard, Christian, Monnet, Xavier, Chemla, Denis, Jerbi, Salma, Khedhiri, Wafa, Necib, Hatem, Scarfo, Paolo, Chevalier, Charles, Piagnerelli, Michael, Lafont, Alexandre, Galy, Antoine, Mancia, Claire, Zerhouni, Amel, Tabeliouna, Kheira, Gaja, Ali, Hamrouni, Bassem, Malouch, Abir, Fourati, Sami, Messaoud, Rihab, Zarrouki, Youssef, Ziadi, Amra, Rhezali, Manal, Zouizra, Zahira, Boumzebra, Drissi, Samkaoui, Mohamed Abdennasser, Brunet, Jennifer, Canoville, Bertrand, Verrier, Pierre, Ivascau, Calin, Seguin, Amélie, Valette, Xavier, Du Cheyron, Damien, Daubin, Cedric, Bougouin, Wulfran, Aissaoui, Nadia, Lamhaut, Lionel, Jost, Daniel, Maupain, Carole, Beganton, Frankie, Bouglé, Adrien, Dumas, Florence, Marijon, Eloi, Jouven, Xavier, Cariou, Alain, Poirson, Florent, Chaput, Ulriikka, Beeken, Thomas, Maxime, Leclerc, Haikel, Oueslati, Vodovar, Dominique, Chelly, Jonathan, Marteau, Philippe, Chocron, Richard, Juvin, Philippe, Loeb, Thomas, Adnet, Frederic, Lecarpentier, Eric, Riviere, Antoine, De Cagny, Bertand, Soupison, Thierry, Privat, Elodie, Escutnaire, Joséphine, Dumont, Cyrielle, Baert, Valentine, Vilhelm, Christian, Hubert, Hervé, Leteurtre, Stéphane, Fresco, Marion, Bubenheim, Michael, Beduneau, Gaetan, Carpentier, Dorothée, Grange, Steven, Artaud-Macari, Elise, Misset, Benoit, Tamion, Fabienne, Girault, Christophe, Dumas, Guillaume, Chevret, Sylvie, Lemiale, Virginie, Mokart, Djamel, Mayaux, Julien, Pène, Frédéric, Nyunga, Martine, Perez, Pierre, Moreau, Anne-Sophie, Bruneel, Fabrice, Vincent, François, Klouche, Kada, Reignier, Jean, Rabbat, Antoine, Azoulay, Elie, Frat, Jean-Pierre, Ragot, Stéphanie, Constantin, Jean-Michel, Prat, Gwenael, Mercat, Alain, Boulain, Thierry, Demoule, Alexandre, Devaquet, Jérôme, Nseir, Saad, Charpentier, Julien, Argaud, Laurent, Beuret, Pascal, Ricard, Jean-Damien, Teiten, Christelle, Marjanovic, Nicolas, Palamin, Nicola, L’Her, Erwan, Bailly, Arthur, Boisramé-Helms, Julie, Champigneulle, Benoit, Kamel, Toufik, Mercier, Emmanuelle, Le Thuaut, Aurélie, Lascarrou, Jean-Baptiste, Rolle, Amélie, De Jong, Audrey, Chanques, Gérald, Jaber, Samir, Hariri, Geoffroy, Baudel, Jean-Luc, Dubée, Vincent, Preda, Gabriel, Bourcier, Simon, Joffre, Jeremie, Bigé, Naïke, Ait-Oufella, Hafid, Maury, Eric, Mater, Houda, Merdji, Hamid, Grimaldi, David, Rousseau, Christophe, Mira, Jean-Paul, Chiche, Jean-Daniel, Sedghiani, Ines, Benabderrahim, A., Hamdi, Dhekra, Jendoubi, Asma, Cherif, Mohamed Ali, Hechmi, Youssef Zied El, Zouheir, Jerbi, Bagate, François, Bousselmi, Radhwen, Schortgen, Frédérique, Asfar, Pierre, Guérot, Emmanuel, Fabien, Grelon, Anguel, Nadia, Sigismond, Lasocki, Matthieu, Henry-Lagarrigue, Gonzalez, Frédéric, François, Legay, Guitton, Christophe, Schenck, Maleka, Jean-Marc, Doise, Dreyfuss, Didier, Radermacher, Peter, Frère, Antoine, Martin-Lefèvre, Laurent, Colin, Gwenhaël, Fiancette, Maud, Henry-Laguarrigue, Matthieu, Lacherade, Jean-Claude, Lebert, Christine, Vinatier, Isabelle, Yehia, Aihem, Joret, Aurélie, Menunier-Beillard, Nicolas, Benzekri-Lefevre, Dalila, Desachy, Arnaud, Bellec, Fréderic, Plantefève, Gaëtan, Quenot, Jean-Pierre, Meziani, Ferhat, Tavernier, Elsa, Ehrmann, Stephan, Chudeau, Nicolas, Raveau, Tommy, Moal, Valérie, Houillier, Pascal, Rouve, Emmanuelle, Lakhal, Karim, Gandonnière, Charlotte Salmon, Jouan, Youenn, Bodet-Contentin, Laetitia, Balmier, Adrien, Messika, Jonathan, De Montmollin, Etienne, Pouyet, Victorine, Sztrymf, Benjamin, Thiagarajah, Abirami, Roux, Damien, De Chambrun, Marc Pineton, Luyt, Charles-Edouard, Beloncle, François, Zapella, Nathalie, Ledochowsky, Stanislas, Terzi, Nicolas, Mazou, Jean-Marc, Sonneville, Romain, Paulus, Sylvie, Fedun, Yannick, Landais, Mickael, Raphalen, Jean-Herlé, Combes, Alain, Amoura, Zahir, Jacquemin, Aemilia, Guerrero, Felipe, Marcheix, Bertrand, Hernandez, Nicolas, Fourcade, Olivier, Georges, Bernard, Delmas, Clément, Makoudi, Sarah, Genton, Audrey, Bernard, Rémy, Lebreton, Guillaume, Amour, Julien, Mazet, Charlotte, Bounes, Fanny, Murat, Gurbuz, Cronier, Laure, Robin, Guillaume, Biendel, Caroline, Silva, Stein, Boubeche, Samia, Abriou, Caroline, Wurtz, Véronique, Scherrer, Vincent, Rey, Nathalie, Gastaldi, Gioia, Veber, Benoit, Doguet, Fabien, Gay, Arnaud, Dureuil, Bertrand, Besnier, Emmanuel, Rouget, Antoine, Gantois, Guillaume, Magalhaes, Eric, Wanono, Ruben, Smonig, Roland, Lermuzeaux, Mathilde, Lebut, Jordane, Olivier, Andremont, Dupuis, Claire, Radjou, Aguila, Mourvillier, Bruno, Neuville, Mathilde, D’ortho, Marie Pia, Bouadma, Lila, Rouvel-Tallec, Anny, Rudler, Marika, Weiss, Nicolas, Perlbarg, Vincent, Galanaud, Damien, Thabut, Dominique, Rachdi, Emna, Mhamdi, Ghada, Trifi, Ahlem, Abdelmalek, Rim, Abdellatif, Sami, Daly, Foued, Nasri, Rochdi, Tiouiri, Hanene, Lakhal, Salah Ben, Rousseau, Geoffroy, Asmolov, Romain, Grammatico-Guillon, Leslie, Auvet, Adrien, Laribi, Said, Garot, Denis, Dequin, Pierre François, Guillon, Antoine, Fergé, Jean-Louis, Abgrall, Gwénolé, Hinault, Ronan, Vally, Shazima, Roze, Benoit, Chaplain, Agathe, Chabartier, Cyrille, Savidan, Anne-Charlotte, Marie, Sabia, Cabie, Andre, Resiere, Dabor, Valentino, Ruddy, Mehdaoui, Hossein, Benarous, Lucas, Soda-Diop, Marième, Bouzana, Fouad, Perrin, Gilles, Bourenne, Jeremy, Eon, Béatrice, Lambert, Dominique, Trebuchon, Agnes, Poncelet, Géraldine, Le Bourgeois, Fleur, Michael, Levy, Camille, Guillot, Naudin, Jérôme, Deho, Anna, Dauger, Stéphane, Sauthier, Michaël, Bergeron-Gallant, Krystale, Emeriaud, Guillaume, Jouvet, Philippe, Tiebergien, Nicolas, Jacquet-Lagrèze, Matthias, Fellahi, Jean-Luc, Baudin, Florent, Essouri, Sandrine, Javouhey, Etienne, Guérin, Claude, Lampin, Marie, Mamouri, Ouardia, Devos, Patrick, Karaca-Altintas, Yasemin, Vinchon, Matthieu, Brossier, David, Eltaani, Redha, Teyssedre, Sonia, Sabine, Meyet, Bouchut, Jean-Christophe, Peguet, Olivier, Petitdemange, Lucie, Guilbert, Anne Sophie, Aoul, Nabil Tabet, Addou, Zakaria, Aouffen, Nabil, Anas, Benqqa, Kalouch, Samira, Yaqini, Khalid, Chlilek, Aziz, Abdou, Rchi, Gravellier, Perrine, Chantreuil, Julie, Travers, Nadine, Listrat, Antoine, Le Reun, Claire, Favrais, Geraldine, Coppere, Zoe, Blanot, Stéphane, Montmayeur, Juliette, Bronchard, Régis, Rolando, Stephane, Orliaguet, Gilles, Leger, Pierre-Louis, Rambaud, Jérôme, Thueux, Emilie, De Larrard, Alexandra, Berthelot, Véronique, Denot, Julien, Reymond, Marie, Amblard, Alain, Morin-Zorman, Sarah, Lengliné, Etienne, Pichereau, Claire, Mariotte, Eric, Emmanuel, Canet, Poujade, Julien, Trumpff, Guillaume, Janssen-Langenstein, Ralf, Harlay, Marie-Line, Zaid, Noorah, Ait-Ammar, Nawel, Bonnal, Christine, Merle, Jean-Claude, Botterel, Francoise, Levesque, Eric, Riad, Zakaria, Mezidi, Mehdi, Yonis, Hodane, Aublanc, Mylène, Perinel-Ragey, Sophie, Lissonde, Floriane, Louf-Durier, Aurore, Tapponnier, Romain, Louis, Bruno, Forel, Jean-Marie, Bisbal, Magali, Lehingue, Samuel, Rambaud, Romain, Adda, Mélanie, Hraiech, Sami, Marchi, Elisa, Roch, Antoine, Guerin, Vincent, Rozencwajg, Sacha, Schmidt, Matthieu, Hekimian, Guillaume, Bréchot, Nicolas, Trouillet, Jean Louis, Besset, Sébastien, Franchineau, Guillaume, Nieszkowska, Ania, Pascal, Leprince, Loiselle, Maud, Sarah, Chemam, Laurence, Dangers, Guillemette, Thomas, Jacquens, Alice, Kerever, Sebastien, Guidet, Bertrand, Aegerter, Philippe, Das, Vincent, Fartoukh, Muriel, Hayon, Jan, Desmard, Mathieu, Fulgencio, Jean-Pierre, Zuber, Benjamin, Soufi, A., Khaleq, K., Hamoudi, D., Garret, Charlotte, Peron, Matthieu, Coron, Emmanuel, Bretonnière, Cédric, Audureau, Etienne, Audrey, Winters, Christophe, Duvoux, Christian, Jacquelinet, Daniel, Azoulay, Cyrille, Feray, Aissaoui, Wissal, Rghioui, Kawtar, Haddad, Wafae, Barrou, Houcine, Carteaux-Taeib, Anna, Lupinacci, Renato, Manceau, Gilles, Jeune, Florence, Tresallet, Christophe, Habacha, Sahar, Fathallah, Ines, Zoubli, Aymen, Aloui, Rafaa, Kouraichi, Nadia, Jouet, Emilie, Badin, Julie, Fermier, Brice, Feller, Marc, Serie, Mathieu, Pillot, Jérôme, Marie, William, Gisbert-Mora, Chloé, Vinclair, Camille, Lesbordes, Pierre, Mathieu, Pascal, De Brabant, Fabienne, Muller, Emmanuel, Robaux, Marie-Aline, Giabicani, Mikhael, Marchalot, Antoine, Gelinotte, Stéphanie, Declercq, Pierre Louis, Eraldi, Jean-Pierre, Bougerol, François, Meunier-Beillard, Nicolas, Devilliers, Hervé, Rigaud, Jean-Philippe, Verrière, Camille, Ardisson, Fanny, Kentish-Barnes, Nancy, Jacq, Gwenaëlle, Chermak, Akli, Lautrette, Alexandre, Legrand, Matthieu, Soummer, Alexis, Thiery, Guillaume, Cottereau, Alice, Canet, Emmanuel, Caujolle, Marie, Allyn, Jérôme, Valance, Dorothée, Brulliard, Caroline, Martinet, Olivier, Jabot, Julien, Gallas, Thomas, Vandroux, David, Allou, Nicolas, Durand, Arthur, Nevière, Rémi, Delguste, Florian, Boulanger, Eric, Preau, Sebastien, Martin, Ruste, Cochet, Hélène, Ponthus, Jean Pierre, Amilien, Virginie, Tchir, Martial, Barsam, Elise, Ayoub, Mohsen, Georger, Jean Francois, Guillame, Izaute, Assaraf, Julie, Tripon, Simona, Mallet, Maxime, Barbara, Guilaume, Louis, Guillaume, Gaudry, Stéphane, Barbarot, Nicolas, Jamet, Angéline, Outin, Hervé, Gibot, Sébastien, Bollaert, Pierre-Edouard, Holleville, Mathilde, Legriel, Stéphane, Chateauneuf, Anne Laure, Cavelot, Sébastien, Moyer, Jean-Denis, Bedos, Jean Pierre, Merle, Philippe, Laine, Aurelie, Natalie, De Sa, Cornuault, Mathieu, Libot, Jérome, Asehnoune, Karim, Rozec, Bertrand, Dantal, Jacques, Videcoq, Michel, Degroote, Thècle, Jaillette, Emmanuelle, Zerimech, Farid, Malika, Balduyck, Llitjos, Jean-François, Amara, Marlène, Lacave, Guillaume, Pangon, Béatrice, Mavinga, José, Makunza, Joseph Nsiala, Mafuta, M. E., Yanga, Yves, Eric, Amisi, Ilunga, Jp, Kilembe, Ma, Alby-Laurent, Fanny, Toubiana, Julie, Mokline, Amel, Laajili, Achraf, Amri, Helmi, Rahmani, Imene, Mensi, Nidhal, Gharsallah, Lazheri, Tlaili, Sofiene, Gasri, Bahija, Hammouda, Rym, Messadi, Amen Allah, Allain, Pierre-Antoine, Gault, Nathallie, Paugam-Burtz, Catherine, Foucrier, Arnaud, Chatbri, Bassem, Bourbiaa, Yousra, Thabet, Lamia, Neuschwander, Arthur, Vincent, Looten, Beck, Jennifer, Vibol, Chhor, Amelie, Yavchitz, Resche-Rigon, Matthieu, Pirracchio, Jean MantzRomain, Bureau, Côme, Decavèle, Maxens, Campion, Sébastien, Ainsouya, Roukia, Niérat, Marie-Cécile, Prodanovic, Hélène, Raux, Mathieu, Similowski, Thomas, Dubé, Bruno-Pierre, Demiri, Suela, Dres, Martin, May, Faten, Quintard, Hervé, Kounis, Ilias, Saliba, Faouzi, André, Stephane, Boudon, Marc, Ichai, Philippe, Younes, Aline, Nakad, Lionel, Coilly, Audrey, Antonini, Teresa, Sobesky, Rodolphe, De Martin, Eleonora, Samuel, Didier, Hubert, Noemie, Nay, Mai-Anh, Auchabie, Johann, Giraudeau, Bruno, Jean, Reignier, Darmon, Michaël, Ruckly, Stephane, Garrouste-Orgeas, Maïté, Gratia, Elisabeth, Goldgran-Toledano, Dany, Jamali, Samir, Dumenil, Anne Sylvie, Schwebel, Carole, Brisard, Laurent, Bizouarn, Philippe, Lepoivre, Thierry, Nicolet, Johanna, Rigal, Jean Christophe, Roussel, Jean Christian, Cheurfa, Cherifa, Abily, Julien, Lescot, Thomas, Page, Isaline, Warnier, Stéphanie, Nys, Monique, Rousseau, Anne-Françoise, Damas, Pierre, Uhel, Fabrice, Lesouhaitier, Mathieu, Grégoire, Murielle, Gaudriot, Baptiste, Gacouin, Arnaud, Le Tulzo, Yves, Flecher, Erwan, Tarte, Karin, Tadié, Jean-Marc, Georges, Quentin, Soares, M., Jeon, Kyeongman, Oeyen, Sandra, Rhee, Chin Kook, Gruber, Pascale, Ostermann, Marlies, Hill, Quentin, Depuydt, Peter, Ferra, Christelle, Muller, Alice, Aurelie, Bourmaud, Niles, Christopher, Herbert, Fabien, Pied, Sylviane, Loridant, Séverine, François, Nadine, Bignon, Anne, Sendid, Boualem, Lemaitre, Caroline, Dupre, Celine, Zayene, Aymen, Portier, Lucie, De Freitas Caires, Nathalie, Lassalle, Philippe, Le Neindre, Aymeric, Selot, Pascal, Ferreiro, Daniel, Bonarek, Maria, Henriot, Stépahen, Rodriguez, Julie, Taddei, Mara, Di Bari, Mauro, Hickmann, Cheryl, Castanares-Zapatero, Diego, Deldicque, Louise, Van Den Bergh, Peter, Caty, Gilles, Roeseler, Jean, Francaux, Marc, Laterre, Pierre-François, Dupuis, Bastien, Machayeckhi, Sharam, Sarfati, Celine, Moore, Alex, Mendialdua, Paula, Rodet, Emilie, Pilorge, Catherine, Stephan, Francois, Rezaiguia-Delclaux, Saida, Dugernier, Jonathan, Hesse, Michel, Jumetz, Thibaud, Bialais, Emilie, Depoortere, Virginie, Michotte, Jean Bernard, Wittebole, Xavier, Jamar, François, REA‑RAISIN Studygroup, OUTCOMEREA study group, Sudden Death Expertise Center, for the HYPER2S Investigators and REVA research network, Clinical Research in Intensive Care and Sepsis (CRICS network), Cubrea network, and Brain Liver Pitié-Salpêtrière Study Group (BLIPS)

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2017
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25. Final results of the DisCoVeRy trial of remdesivir for patients admitted to hospital with COVID-19

Author

Ader, Florence, primary, Bouscambert-Duchamp, Maude, additional, Hites, Maya, additional, Peiffer-Smadja, Nathan, additional, Mentré, France, additional, Burdet, Charles, additional, Aboab, Jérôme, additional, Ader, Florence, additional, Ait-Oufella, Hafid, additional, Altdorfer, Antoine, additional, Andrejak, Claire, additional, Andreu, Pascal, additional, Argaud, Laurent, additional, Bani-Sadr, Firouzé, additional, Belhadi, Drifa, additional, Belkhir, Leila, additional, Benezit, François, additional, Berna, Marc, additional, Blot, Mathieu, additional, Botelho-Nevers, Elisabeth, additional, Bouadma, Lila, additional, Bouchaud, Olivier, additional, Bougon, David, additional, Bouiller, Kevin, additional, Bounes-Vardon, Fanny, additional, Boutoille, David, additional, Boyer, Alexandre, additional, Braz, Sandra, additional, Bruel, Cédric, additional, Cabié, André, additional, Canet, Emmanuel, additional, Cazanave, Charles, additional, Chabartier, Cyrille, additional, Chirouze, Catherine, additional, Clere-Jehl, Raphaël, additional, Costagliola, Dominique, additional, Couffin-Cadièrgues, Sandrine, additional, Courjon, Johan, additional, Crockett, Flora, additional, Danion, François, additional, Dechanet, Aline, additional, Delbove, Agathe, additional, Dellamonica, Jean, additional, Delmas, Christelle, additional, Diallo, Alpha, additional, Djossou, Félix, additional, Dubost, Clément, additional, Duvignaud, Alexandre, additional, Egle, Alexander, additional, Epaulard, Olivier, additional, Epelboin, Loïc, additional, Esperou, Hélène, additional, Fartoukh, Murielle, additional, Faure, Karine, additional, Faure, Emmanuel, additional, Ferreira Ribeiro, Joao-Miguel, additional, Ferry, Tristan, additional, Ficko, Cécile, additional, Figueiredo, Samy, additional, Fougerou, Claire, additional, Fraipont, Vincent, additional, Gaborit, Benjamin, additional, Gaci, Rostane, additional, Gagneux-Brunon, Amandine, additional, Gallien, Sébastien, additional, Garot, Denis, additional, Gaymard, Alexandre, additional, Geri, Guillaume, additional, Gibot, Sébastien, additional, Goehringer, François, additional, Gousseff, Marie, additional, Greil, Richard, additional, Gruson, Didier, additional, Guedj, Jérémie, additional, Hansmann, Yves, additional, Hinschberger, Olivier, additional, Jaureguiberry, Stéphane, additional, Jeanmichel, Vanessa, additional, Joannidis, Michael, additional, Kerneis, Solen, additional, Kimmoun, Antoine, additional, Klouche, Kada, additional, Lachâtre, Marie, additional, Lacombe, Karine, additional, Laine, Fabrice, additional, Lamprecht, Bernd, additional, Lanoix, Jean-Philippe, additional, Launay, Odile, additional, Laviolle, Bruno, additional, Lê, Minh-Patrick, additional, Le Moing, Vincent, additional, Le Pavec, Jérôme, additional, Le Tulzo, Yves, additional, Le Turnier, Paul, additional, Lebeaux, David, additional, Lefevre, Benjamin, additional, Leroy, Sylvie, additional, Lescure, François-Xavier, additional, Lessire, Henry, additional, Leveau, Benjamin, additional, Lina, Bruno, additional, Loubet, Paul, additional, Makinson, Alain, additional, Malvy, Denis, additional, Marquette, Charles-Hugo, additional, Martin-Blondel, Guillaume, additional, Martinot, Martin, additional, Mayaux, Julien, additional, Mekontso-Dessap, Armand, additional, Mercier, Noémie, additional, Meziani, Ferhat, additional, Mira, Jean-Paul, additional, Molina, Jean-Michel, additional, Monnet, Xavier, additional, Mootien, Joy, additional, Mourvillier, Bruno, additional, Mourvilliers, Bruno, additional, Murris-Espin, Marlène, additional, Navellou, Jean-Christophe, additional, Noret, Marion, additional, Nseir, Saad, additional, Oulehri, Walid, additional, Paiva, José-Artur, additional, Perpoint, Thomas, additional, Peytavin, Gilles, additional, Pialoux, Gilles, additional, Pilmis, Benoît, additional, Piriou, Vincent, additional, Piroth, Lionel, additional, Poissy, Julien, additional, Pourcher, Valérie, additional, Quenot, Jean-Pierre, additional, Raffi, François, additional, Reignier, Jean, additional, Reuter, Jean, additional, Revest, Matthieu, additional, Richard, Jean-Christophe, additional, Riu-Poulenc, Béatrice, additional, Robert, Céline, additional, Roger, Pierre-Alexandre, additional, Roger, Claire, additional, Roncon-Albuquerque, Roberto, additional, Rouveix-Nordon, Elisabeth, additional, Ruch, Yvon, additional, Saidani, Nadia, additional, Saillard, Juliette, additional, Sayre, Naomi, additional, Senneville, Eric, additional, Sotto, Albert, additional, Staub, Thérèse, additional, Stefan, Francois, additional, Tacquard, Charles, additional, Terzi, Nicolas, additional, Textoris, Julien, additional, Thiery, Guillaume, additional, Timsit, Jean-François, additional, Tolsma, Violaine, additional, Tubiana, Sarah, additional, Turmel, Jean-Marie, additional, Valour, Florent, additional, Vardon-Bounes, Fanny, additional, Velou, Priyanka, additional, Verschelden, Gil, additional, Wallet, Florent, additional, Wattecamps, Guilhem, additional, Yazdanpanah, Yazdan, additional, and Zerbib, Yoann, additional

Published
2022
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26. Impact of Arterial CO2 Retention in Patients With Moderate or Severe ARDS.

Author

Maamar, Adel, Delamaire, Flora, Reizine, Florian, Lesouhaitier, Mathieu, Painvin, Benoit, Quelven, Quentin, Coirier, Valentin, Guillot, Pauline, Le Tulzo, Yves, Tadié, Jean Marc, and Gacouin, Arnaud

Subjects
INTENSIVE care units, PNEUMONIA, STATISTICS, CONFIDENCE intervals, TIME, MULTIPLE regression analysis, RADIOGRAPHY, RETROSPECTIVE studies, MANN Whitney U Test, ADULT respiratory distress syndrome, ARTIFICIAL respiration, COMPARATIVE studies, CARBON dioxide, DESCRIPTIVE statistics, CHI-squared test, OBSTRUCTIVE lung diseases, HYPERCAPNIA, ODDS ratio, DEATH, DATA analysis, LONGITUDINAL method, PROBABILITY theory, ACIDOSIS
Abstract

Background: Lung-protective ventilation (reduced tidal volume and limited plateau pressure) may lead to CO2 retention. Data about the impact of hypercapnia in patients with ARDS are scarce and conflicting. Methods: We performed a non-interventional cohort study with subjects with ARDS admitted from 2006 to 2021 and with PaO2 /FIO2 ≤ 150 mm Hg. We examined the association between severe hypercapnia (PaCO2 ≥ 50 mm Hg) on the first 5 days after the diagnosis of ARDS and death in ICU for 930 subjects. All the subjects received lung-protective ventilation. Results: Severe hypercapnia was noted in 552 subjects (59%) on the first day of ARDS (day 1); 323/930 (34.7%) died in the ICU. Severe hypercapnia on day 1 was associated with mortality in the unadjusted (odds ratio 1.54, 95% CI 1.16-1.63; P = .003) and adjusted (odds ratio 1.47, 95% CI 1.08-2.43; P = .004) models. In the Bayesian analysis, the posterior probability that severe hypercapnia was associated with ICU death was > 90% in 4 different priors, including a septic prior for this association. Sustained severe hypercapnia on day 5, defined as severe hypercapnia present from day 1 to day 5, was noted in 93 subjects (12%). After propensity score matching, severe hypercapnia on day 5 remained associated with ICU mortality (odds ratio 1.73, 95% CI 1.02-2.97; P = .047). Conclusions: Severe hypercapnia was associated with mortality in subjects with ARDS who received lung-protective ventilation. Our results deserve further evaluation of the strategies and treatments that aim to control CO2 retention. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Additional file 1 of Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial

Author

Fage, Nicolas, Demiselle, Julien, Seegers, Valérie, Merdji, Hamid, Grelon, Fabien, Mégarbane, Bruno, Anguel, Nadia, Mira, Jean-Paul, Dequin, Pierre-François, Gergaud, Soizic, Weiss, Nicolas, Legay, François, Le Tulzo, Yves, Conrad, Marie, Coudroy, Remi, Gonzalez, Frédéric, Guitton, Christophe, Tamion, Fabienne, Tonnelier, Jean-Marie, Bedos, Jean Pierre, Van Der Linden, Thierry, Vieillard-Baron, Antoine, Mariotte, Eric, Pradel, Gaël, Lesieur, Olivier, Ricard, Jean-Damien, Hervé, Fabien, Du Cheyron, Damien, Guerin, Claude, Mercat, Alain, Teboul, Jean-Louis, Radermacher, Peter, and Asfar, Pierre

Abstract

Additional file 1. Additional Tables.

Published
2022
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28. 1-hour t-piece spontaneous breathing trial vs 1-hour zero pressure support spontaneous breathing trial and reintubation at day 7: A non-inferiority approach

Author

Gacouin, Arnaud, Lesouhaitier, Mathieu, Reizine, Florian, Painvin, Benoit, Maamar, Adel, Camus, Christophe, Le Tulzo, Yves, Tadie, Jean Marc, CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Biosit : biologie, santé, innovation technologique (SFR UMS CNRS 3480 - INSERM 018), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes 1 - Faculté de Médecine (UR1 Médecine), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes - Faculté de Médecine (UR Médecine), Université de Rennes (UR), This research did not receive any specific grant from funding agencies in the public, commercial, or not-for- profit sectors., and Jonchère, Laurent

Subjects
[SDV] Life Sciences [q-bio], Positive-Pressure Respiration, Mechanical ventilation, Ventilator weaning, Extubation outcome, [SDV]Life Sciences [q-bio], Airway Extubation, Intubation, Intratracheal, Spontaneous breathing trial, Humans, Cohort study, Respiration, Artificial, Pressure support ventilation
Abstract

International audience; Purpose: Physiological data suggest that T-piece and zero pressure support (PS0) ventilation both accurately reflect spontaneous breathing conditions after extubation. These two types of spontaneous breathing trials (SBTs) are used in our Intensive Care Unit to evaluate patients for extubation readiness and success but have rarely been compared in clinical studies. Materials and methods: We performed a prospective observational study to confirm the hypothesis that 1-hour T-piece SBT and 1-h PS0 zero PEEP (ZEEP) SBT are associated with similar rates of reintubation at day 7 after extubation. A non-inferiority approach was used for sample size calculation. Results: The cohort consisted of 529 subjects invasively ventilated for more than 24 h and extubated after successful 1-hour T-piece SBT (n = 303, 57%) or 1-h PS0 ZEEP SBT (n = 226, 43%). The reintubation rate at day 7 was 14.6% with PS0 ZEEP and 17.5% with T-piece (difference - 2.6% [95% confidence interval, -8.3% to 4.3%]; p = 0.40). The reasons for reintubation did not differ significantly when compared between patients with 1-h PS0 ZEEP SBT and patients with 1-hour T-piece SBT. Conclusion: Our results suggest that successful 1-hour T-piece and 1-h PSO ZEEP SBTs are associated with similar reintubation rates at day 7. (c) 2021 Published by Elsevier Inc.

Published
2022

29. Additional file 2 of Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial

Author

Fage, Nicolas, Demiselle, Julien, Seegers, Valérie, Merdji, Hamid, Grelon, Fabien, Mégarbane, Bruno, Anguel, Nadia, Mira, Jean-Paul, Dequin, Pierre-François, Gergaud, Soizic, Weiss, Nicolas, Legay, François, Le Tulzo, Yves, Conrad, Marie, Coudroy, Remi, Gonzalez, Frédéric, Guitton, Christophe, Tamion, Fabienne, Tonnelier, Jean-Marie, Bedos, Jean Pierre, Van Der Linden, Thierry, Vieillard-Baron, Antoine, Mariotte, Eric, Pradel, Gaël, Lesieur, Olivier, Ricard, Jean-Damien, Hervé, Fabien, Du Cheyron, Damien, Guerin, Claude, Mercat, Alain, Teboul, Jean-Louis, Radermacher, Peter, and Asfar, Pierre

Abstract

Additional file 2. Additional Figures.

Published
2022
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31. Non-invasive ventilation versus high-flow nasal oxygen for postextubation respiratory failure in ICU: a post-hoc analysis of a randomized clinical trial

Author

Thille, Arnaud, Monseau, Grégoire, Coudroy, Rémi, Nay, Mai-Anh, Gacouin, Arnaud, Decavèle, Maxens, Sonneville, Romain, Beloncle, François, Girault, Christophe, Dangers, Laurence, Lautrette, Alexandre, Levrat, Quentin, Rouzé, Anahita, Vivier, Emmanuel, Lascarrou, Jean-Baptiste, Ricard, Jean-Damien, Razazi, Keyvan, Barberet, Guillaume, Lebert, Christine, Ehrmann, Stephan, Massri, Alexandre, Bourenne, Jeremy, Pradel, Gael, Bailly, Pierre, Terzi, Nicolas, Dellamonica, Jean, Lacave, Guillaume, Robert, René, Ragot, Stéphanie, Frat, Jean-Pierre, Boissier, Florence, Chatellier, Delphine, Deletage, Céline, Guignon, Carole, Joly, Florent, Olivry, Morgane, Veinstein, Anne, Benzekri-Lefevre, Dalila, Boulain, Thierry, Muller, Grégoire, Le Tulzo, Yves, Tadié, Jean-Marc, Maamar, Adel, Demiri, Suela, Mayaux, Julien, Demoule, Alexandre, Bouadma, Lila, Dupuis, Claire, Asfar, Pierre, Pierrot, Marc, Béduneau, Gaëtan, Boyer, Déborah, Delmas, Benjamin, Puech, Bérénice, Bachoumas, Konstantinos, Soum, Edouard, Cabasson, Séverin, Hoppe, Marie-Anne, Nseir, Saad, Pouly, Olivier, Bourdin, Gaël, Rosselli, Sylvène, Le Meur, Anthony, Garret, Charlotte, Martin, Maelle, Berquier, Guillaume, Thiagarajah, Abirami, Carteaux, Guillaume, Mekontso-Dessap, Armand, Poidevin, Antoine, Dureau, Anne-Florence, Azais, Marie-Ange, Colin, Gwenhaël, Mercier, Emmanuelle, Morisseau, Marlène, Sabatier, Caroline, Picard, Walter, Gainnier, Marc, Nguyen, Thi-My-Hue, Prat, Gwenaël, Schwebel, Carole, Buscot, Matthieu, Service de Médecine Intensive Réanimation [Tours], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), and Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Male, chemistry.chemical_element, Airway Extubation, Kaplan-Meier Estimate, Critical Care and Intensive Care Medicine, Acute respiratory failure, Oxygen, [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Ventilator weaning, Intensive care, Post-hoc analysis, Medicine, Humans, Aged, Aged, 80 and over, Noninvasive Ventilation, RC86-88.9, business.industry, Research, Airway extubation, Oxygen Inhalation Therapy, Medical emergencies. Critical care. Intensive care. First aid, 030208 emergency & critical care medicine, Oxygenation, Length of Stay, Middle Aged, High-flow nasal oxygen, 3. Good health, Intensive Care Units, 030228 respiratory system, Respiratory failure, chemistry, Anesthesia, Female, medicine.symptom, business, Respiratory Insufficiency, Hypercapnia
Abstract

Background In intensive care units (ICUs), patients experiencing post-extubation respiratory failure have poor outcomes. The use of noninvasive ventilation (NIV) to treat post-extubation respiratory failure may increase the risk of death. This study aims at comparing mortality between patients treated with NIV alternating with high-flow nasal oxygen or high-flow nasal oxygen alone. Methods Post-hoc analysis of a multicenter, randomized, controlled trial focusing on patients who experienced post-extubation respiratory failure within the 7 days following extubation. Patients were classified in the NIV group or the high-flow nasal oxygen group according to oxygenation strategy used after the onset of post-extubation respiratory failure. Patients reintubated within the first hour after extubation and those promptly reintubated without prior treatment were excluded. The primary outcome was mortality at day 28 after the onset of post-extubation respiratory failure. Results Among 651 extubated patients, 158 (25%) experienced respiratory failure and 146 were included in the analysis. Mortality at day 28 was 18% (15/84) using NIV alternating with high-flow nasal oxygen and 29% (18/62) with high flow nasal oxygen alone (difference, − 11% [95% CI, − 25 to 2]; p = 0.12). Among the 46 patients with hypercapnia at the onset of respiratory failure, mortality at day 28 was 3% (1/33) with NIV and 31% (4/13) with high-flow nasal oxygen alone (difference, − 28% [95% CI, − 54 to − 6]; p = 0.006). The proportion of patients reintubated 48 h after the onset of post-extubation respiratory failure was 44% (37/84) with NIV and 52% (32/62) with high-flow nasal oxygen alone (p = 0.21). Conclusions In patients with post-extubation respiratory failure, NIV alternating with high-flow nasal oxygen might not increase the risk of death. Trial registration number The trial was registered at http://www.clinicaltrials.gov with the registration number NCT03121482 the 20th April 2017.

Published
2021

32. Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction

Author

Reizine, Florian, primary, Grégoire, Murielle, additional, Lesouhaitier, Mathieu, additional, Coirier, Valentin, additional, Gauthier, Juliette, additional, Delaloy, Céline, additional, Dessauge, Elise, additional, Creusat, Florent, additional, Uhel, Fabrice, additional, Gacouin, Arnaud, additional, Dessauge, Frédéric, additional, Le Naoures, Cécile, additional, Moreau, Caroline, additional, Bendavid, Claude, additional, Daniel, Yoann, additional, Petitjean, Kilian, additional, Bordeau, Valérie, additional, Lamaison, Claire, additional, Piau, Caroline, additional, Cattoir, Vincent, additional, Roussel, Mikael, additional, Fromenty, Bernard, additional, Michelet, Christian, additional, Le Tulzo, Yves, additional, Zmijewski, Jaroslaw, additional, Thibault, Ronan, additional, Cogné, Michel, additional, Tarte, Karin, additional, and Tadié, Jean-Marc, additional

Published
2022
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33. Beneficial Effects of Noninvasive Ventilation after Extubation in Obese or Overweight Patients: A Post Hoc Analysis of a Randomized Clinical Trial

Author

Thille, Arnaud W., primary, Coudroy, Rémi, additional, Nay, Mai-Anh, additional, Gacouin, Arnaud, additional, Decavèle, Maxens, additional, Sonneville, Romain, additional, Beloncle, François, additional, Girault, Christophe, additional, Dangers, Laurence, additional, Lautrette, Alexandre, additional, Levrat, Quentin, additional, Rouzé, Anahita, additional, Vivier, Emmanuel, additional, Lascarrou, Jean-Baptiste, additional, Ricard, Jean-Damien, additional, Mekontso-Dessap, Armand, additional, Barberet, Guillaume, additional, Lebert, Christine, additional, Ehrmann, Stephan, additional, Massri, Alexandre, additional, Bourenne, Jeremy, additional, Pradel, Gael, additional, Bailly, Pierre, additional, Terzi, Nicolas, additional, Dellamonica, Jean, additional, Lacave, Guillaume, additional, Robert, René, additional, Frat, Jean-Pierre, additional, Ragot, Stéphanie, additional, Boissier, Florence, additional, Chatellier, Delphine, additional, Deletage, Céline, additional, Guignon, Carole, additional, Joly, Florent, additional, Olivry, Morgane, additional, Veinstein, Anne, additional, Benzekri-Lefevre, Dalila, additional, Boulain, Thierry, additional, Muller, Grégoire, additional, Le Tulzo, Yves, additional, Tadié, Jean-Marc, additional, Maamar, Adel, additional, Demiri, Suela, additional, Mayaux, Julien, additional, Demoule, Alexandre, additional, Bouadma, Lila, additional, Dupuis, Claire, additional, Asfar, Pierre, additional, Pierrot, Marc, additional, Béduneau, Gaëtan, additional, Boyer, Déborah, additional, Delmas, Benjamin, additional, Puech, Bérénice, additional, Bachoumas, Konstantinos, additional, Soum, Edouard, additional, Cabasson, Séverin, additional, Hoppe, Marie-Anne, additional, Nseir, Saad, additional, Pouly, Olivier, additional, Bourdin, Gaël, additional, Rosselli, Sylvène, additional, Le Meur, Anthony, additional, Garret, Charlotte, additional, Martin, Maelle, additional, Berquier, Guillaume, additional, Thiagarajah, Abirami, additional, Carteaux, Guillaume, additional, Razazi, Keyvan, additional, Poidevin, Antoine, additional, Dureau, Anne-Florence, additional, Azais, Marie-Ange, additional, Colin, Gwenhaël, additional, Mercier, Emmanuelle, additional, Morisseau, Marlène, additional, Sabatier, Caroline, additional, Picard, Walter, additional, Gainnier, Marc, additional, Nguyen, Thi-My-Hue, additional, Prat, Gwenaël, additional, Schwebel, Carole, additional, and Buscot, Matthieu, additional

Published
2022
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34. Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial

Author

Ader, Florence, primary, Bouscambert-Duchamp, Maude, additional, Hites, Maya, additional, Peiffer-Smadja, Nathan, additional, Poissy, Julien, additional, Belhadi, Drifa, additional, Diallo, Alpha, additional, Lê, Minh-Patrick, additional, Peytavin, Gilles, additional, Staub, Thérèse, additional, Greil, Richard, additional, Guedj, Jérémie, additional, Paiva, Jose-Artur, additional, Costagliola, Dominique, additional, Yazdanpanah, Yazdan, additional, Burdet, Charles, additional, Mentré, France, additional, Egle, Alexander, additional, Joannidis, Michael, additional, Lamprecht, Bernd, additional, Altdorfer, Antoine, additional, Belkhir, Leila, additional, Fraipont, Vincent, additional, Verschelden, Gil, additional, Aboab, Jérôme, additional, Ader, Florence, additional, Ait-Oufella, Hafid, additional, Andrejak, Claire, additional, Andreu, Pascal, additional, Argaud, Laurent, additional, Bani-Sadr, Firouzé, additional, Benezit, François, additional, Blot, Mathieu, additional, Botelho-Nevers, Elisabeth, additional, Bouadma, Lila, additional, Bouchaud, Olivier, additional, Bougon, David, additional, Bouiller, Kevin, additional, Bounes-Vardon, Fanny, additional, Boutoille, David, additional, Boyer, Alexandre, additional, Bruel, Cédric, additional, Cabié, André, additional, Canet, Emmanuel, additional, Cazanave, Charles, additional, Chabartier, Cyrille, additional, Chirouze, Catherine, additional, Clere-Jehl, Raphaël, additional, Courjon, Johan, additional, Crockett, Flora, additional, Danion, François, additional, Delbove, Agathe, additional, Dellamonica, Jean, additional, Djossou, Félix, additional, Dubost, Clément, additional, Duvignaud, Alexandre, additional, Epaulard, Olivier, additional, Epelboin, Loïc, additional, Fartoukh, Murielle, additional, Faure, Karine, additional, Faure, Emmanuel, additional, Ferry, Tristan, additional, Ficko, Cécile, additional, Figueiredo, Samy, additional, Gaborit, Benjamin, additional, Gaci, Rostane, additional, Gagneux-Brunon, Amandine, additional, Gallien, Sébastien, additional, Garot, Denis, additional, Geri, Guillaume, additional, Gibot, Sébastien, additional, Goehringer, François, additional, Gousseff, Marie, additional, Gruson, Didier, additional, Hansmann, Yves, additional, Hinschberger, Olivier, additional, Jaureguiberry, Stéphane, additional, Jeanmichel, Vanessa, additional, Kerneis, Solen, additional, Kimmoun, Antoine, additional, Klouche, Kada, additional, Lachâtre, Marie, additional, Lacombe, Karine, additional, Laine, Fabrice, additional, Lanoix, Jean-Philippe, additional, Launay, Odile, additional, Laviolle, Bruno, additional, Le Moing, Vincent, additional, Le Pavec, Jérôme, additional, Le Tulzo, Yves, additional, Le Turnier, Paul, additional, Lebeaux, David, additional, Lefevre, Benjamin, additional, Leroy, Sylvie, additional, Lescure, François-Xavier, additional, Lessire, Henry, additional, Leveau, Benjamin, additional, Loubet, Paul, additional, Makinson, Alain, additional, Malvy, Denis, additional, Marquette, Charles-Hugo, additional, Martin-Blondel, Guillaume, additional, Martinot, Martin, additional, Mayaux, Julien, additional, Mekontso-Dessap, Armand, additional, Meziani, Ferhat, additional, Mira, Jean-Paul, additional, Molina, Jean-Michel, additional, Monnet, Xavier, additional, Mootien, Joy, additional, Mourvillier, Bruno, additional, Murris-Espin, Marlène, additional, Navellou, Jean-Christophe, additional, Nseir, Saad, additional, Oulehri, Walid, additional, Perpoint, Thomas, additional, Pialoux, Gilles, additional, Pilmis, Benoît, additional, Piriou, Vincent, additional, Piroth, Lionel, additional, Pourcher, Valérie, additional, Quenot, Jean-Pierre, additional, Raffi, François, additional, Reignier, Jean, additional, Revest, Matthieu, additional, Richard, Jean-Christophe, additional, Riu-Poulenc, Béatrice, additional, Robert, Céline, additional, Roger, Pierre-Alexandre, additional, Roger, Claire, additional, Rouveix-Nordon, Elisabeth, additional, Ruch, Yvon, additional, Saidani, Nadia, additional, Sayre, Naomi, additional, Senneville, Eric, additional, Sotto, Albert, additional, Stefan, Francois, additional, Tacquard, Charles, additional, Terzi, Nicolas, additional, Textoris, Julien, additional, Thiery, Guillaume, additional, Timsit, Jean-François, additional, Tolsma, Violaine, additional, Turmel, Jean-Marie, additional, Valour, Florent, additional, Wallet, Florent, additional, Wattecamps, Guilhem, additional, Zerbib, Yoann, additional, Berna, Marc, additional, Reuter, Jean, additional, Braz, Sandra, additional, Ferreira Ribeiro, Joao-Miguel, additional, Paiva, José-Artur, additional, Roncon-Albuquerque, Roberto, additional, Gaymard, Alexandre, additional, Lina, Bruno, additional, Tubiana, Sarah, additional, Couffin-Cadièrgues, Sandrine, additional, Esperou, Hélène, additional, Dechanet, Aline, additional, Delmas, Christelle, additional, Fougerou, Claire, additional, Mercier, Noémie, additional, Noret, Marion, additional, Saillard, Juliette, additional, and Velou, Priyanka, additional

Published
2022
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35. Effects of Mean Arterial Pressure Target on Mottling and Arterial Lactate Normalization in Patients with Septic Shock: A Post-Hoc Analysis of the SEPSISPAM Trial

Author

Fage, Nicolas, primary, DEMISELLE, Julien, additional, SEEGERS, Valérie, additional, MERDJI, Hamid, additional, GRELON, Fabien, additional, Megarbane, Bruno, additional, ANGUEL, Nadia, additional, Mira, Jean-Paul, additional, DEQUIN, Pierre-François, additional, GERGAUD, Soizic, additional, WEISS, Nicolas, additional, LEGAY, François, additional, Le Tulzo, Yves, additional, Conrad, Marie, additional, Coudroy, Rémi, additional, GONZALEZ, Frédéric, additional, Guitton, Christophe, additional, Tamion, Fabienne, additional, TONNELIER, Jean-Marie, additional, BEDOS, Jean Pierre, additional, VAN DER LINDEN, Thierry, additional, Vieillard-Baron, Antoine, additional, MARIOTTE, Eric, additional, PRADEL, Gaël, additional, LESIEUR, Olivier, additional, Ricard, Jean-Damien, additional, HERVE, Fabien, additional, DU CHEYRON, Damien, additional, Guerin, Claude, additional, MERCAT, Alain, additional, Teboul, Jean-Louis, additional, RADERMACHER, Peter, additional, and Asfar, Pierre, additional

Published
2022
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42. Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass

Author

Lesouhaitier, Mathieu, primary, Gregoire, Murielle, additional, Gacouin, Arnaud, additional, Coirier, Valentin, additional, Frerou, Aurélien, additional, Piau, Caroline, additional, Cattoir, Vincent, additional, Dumontet, Erwan, additional, Revest, Matthieu, additional, Tattevin, Pierre, additional, Roisne, Antoine, additional, Verhoye, Jean-Philippe, additional, Flecher, Erwan, additional, Le Tulzo, Yves, additional, Tarte, Karin, additional, and Tadié, Jean-Marc, additional

Published
2021
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45. High versus Low Blood-Pressure Target in Patients with Septic Shock

Author

Asfar, Pierre, Meziani, Ferhat, Hamel, Jean-François, Grelon, Fabien, Megarbane, Bruno, Anguel, Nadia, Mira, Jean-Paul, Dequin, Pierre-François, Gergaud, Soizic, Weiss, Nicolas, Legay, François, Le Tulzo, Yves, Conrad, Marie, Robert, René, Gonzalez, Frédéric, Guitton, Christophe, Tamion, Fabienne, Tonnelier, Jean-Marie, Guezennec, Pierre, Van Der Linden, Thierry, Vieillard-Baron, Antoine, Mariotte, Eric, Pradel, Gaël, Lesieur, Olivier, Ricard, Jean-Damien, Hervé, Fabien, du Cheyron, Damien, Guerin, Claude, Mercat, Alain, Teboul, Jean-Louis, and Radermacher, Peter

Published
2014
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46. Influenza- and COVID-19-Associated Pulmonary Aspergillosis: Are the Pictures Different?

Author

Reizine, Florian, primary, Pinceaux, Kieran, additional, Lederlin, Mathieu, additional, Autier, Brice, additional, Guegan, Hélène, additional, Gacouin, Arnaud, additional, Luque-Paz, David, additional, Boglione-Kerrien, Christelle, additional, Bacle, Astrid, additional, Le Daré, Brendan, additional, Launey, Yoann, additional, Lesouhaitier, Mathieu, additional, Painvin, Benoit, additional, Camus, Christophe, additional, Mansour, Alexandre, additional, Robert-Gangneux, Florence, additional, Belaz, Sorya, additional, Le Tulzo, Yves, additional, Tadié, Jean-Marc, additional, Maamar, Adel, additional, and Gangneux, Jean-Pierre, additional

Published
2021
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47. Monitoring Transcutaneously Measured Partial Pressure of CO2 During Intubation in Critically Ill Subjects

Author

Frérou, Aurélien, primary, Maamar, Adel, additional, Rafi, Sonia, additional, Lhommet, Claire, additional, Phelouzat, Pierre, additional, Pontis, Emmanuel, additional, Reizine, Florian, additional, Lesouhaitier, Mathieu, additional, Camus, Christophe, additional, Le Tulzo, Yves, additional, Tadié, Jean-Marc, additional, and Gacouin, Arnaud, additional

Published
2021
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48. Is the COVID-19 Pandemic a Good Time to Include Aspergillus Molecular Detection to Categorize Aspergillosis in ICU Patients? A Monocentric Experience

Author

Gangneux, J-P, Reizine, Florian, Guegan, Hélène, Pinceaux, Kieran, Le Balch, Pierre, Prat, Emilie, Pelletier, Romain, Belaz, Sorya, Le Souhaitier, Mathieu, Le Tulzo, Yves, Seguin, Philippe, Lederlin, Mathieu, Tadié, Jean-Marc, Robert-Gangneux, Florence, CHU Pontchaillou [Rennes], Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
invasive aspergillosis, Sars-CoV-2, COVID-19, Article, probable, Aspergillus, PCR, putative, classification, lcsh:Biology (General), [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, galactomannan, ICU, lcsh:QH301-705.5
Abstract

(1) Background: The diagnosis of invasive aspergillosis (IA) in an intensive care unit (ICU)remains a challenge and the COVID-19 epidemic makes it even harder. Here, we evaluatedAspergillus PCR input to help classifying IA in SARS-CoV-2-infected patients. (2) Methods: 45COVID-19 patients were prospectively monitored twice weekly for Aspergillus markers and anti-Aspergillus serology. We evaluated the concordance between (&Iota, ) Aspergillus PCR and culture inrespiratory samples, and (&Iota, &Iota, ) blood PCR and serum galactomannan. Patients were classified asputative/proven/colonized using AspICU algorithm and two other methods. (3) Results: Theconcordance of techniques applied on respiratory and blood samples was moderate (kappa = 0.58and kappa = 0.63, respectively), with a higher sensitivity of PCR. According to AspICU, 9/45 patientswere classified as putative IA. When incorporating PCR results, 15 were putative IA because theymet all criteria, probably with a lack of specificity in the context of COVID-19. Using a modifiedAspICU algorithm, eight patients were classified as colonized and seven as putative IA. (4)Conclusion: An appreciation of the fungal burden using PCR and Aspergillus serology was addedto propose a modified AspICU algorithm. This proof of concept seemed relevant, as it was inagreement with the outcome of patients, but will need validation in larger cohorts.

Published
2020

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