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5. Contributors

Author

Agwu, Ginika, Akyüz, Sinem Helvacıoğlu, Almukhtar, Lana, Alwood, J.S., Baatout, Sarah, Babocs, Dora, Bai, Wei, Barnhart, Heather, Baselet, Bjorn, Beger, Samuel, Benotmane, Mohammed A., Bergouignan, Audrey, Bershad, Eric, Botros, Virina, Brawley, Hayley N., Callas, John L., Christenson, L.K., Christiansen, Rowena, Chung, Michael, Chuva de Sousa Lopes, Susana M., Cools, Ben, Crucian, Brian, Damani, Rahul, Dang, Kai, Deng, Qiwen, Dong, Sude, dos Santos, Marlise A., Drudi, Laura M., Du Plessis, Stefan S., Dunn, Carly, Farooq, Hafiz Muhammad Umer, Fife, Caroline, Fine, Leon G., Franco, Nunzio, Goodwill, Justin, Halicigil, Cihan, Han, Yuexia, Heft, Nicolas, Herbert, Juliana, Huff, Janice L., Jain, Varsha, Kamran, Sharif Amit, Kohut, Adrian, Komorowski, Matthieu, Le Roux, Elisa, Lee, Andrew G., Lee, Peter H.U., Leon Parada, Kathleen, Liu, Tammy, Lowery, Curtis, Luderer, Ulrike, MacKinnon, James, Maheshwari, Kush, Mann, Vivek, Masalkhi, Mouayad, Mathyk, Begum, Mehta, Satish, Melin, M. Mark, Miranda, Silvana, Miserocchi, Giuseppe, Mitchell, Rod T., Nakada, Stephen Y., Narayanan, Amog, Nourianpour, Milad, Novo, Robert T., Olubiyi-Oluwafemi, Ropo A., Oluwafemi, Funmilola A., Omolaoye, Temidayo S., Ong, Joshua, Paladugu, Phani, Patel, Satyam, Patel, Sutchin R., Patil, Suryaji, Pletser, Vladmir, Puukila, S., Qian, Airong, Rajput, Siddharth, Rehnberg, Emil, Rehnberg, Lucas, Reyes, Gabriel, Ronca, A.E., Russomano, Thais, Sarker, Prithul, Scott, Jessica M., Shepanek, Marc A., Shirah, Bader H., Smith, Logan, Smith, Scott M., Steller, J.G., Stewart, Lowan H., St-Martin, Philippe, Stukenborg, Jan-Bernd, Sun, Jianfei, Sundaresan, Alamelu, Tabury, Kevin, Tavakkoli, Alireza, Thompson, Robert J., Trudel, Guy, Van Rompay, Cynthia, Verratti, Vittore, Vinken, Mathieu, Waisberg, Ethan, Wakayama, Sayaka, Wakayama, Teruhiko, Wen, Yanzhong, Werneth, Charles M., Wilson, Christopher, Wu, Zhenyu, Yokota, Koshi, Zaman, Nasif, Zhao, Xin, and Zwart, Sara R.

Published
2025
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6. Effect of exercise on energy expenditure and body composition in astronauts onboard the International Space Station

Author

Pierre, Bourdier, Alexandre, Zahariev, Dale, Schoeller, Isabelle, Chery, Le Roux, Elisa, Cécile, Thevenot, Alain, Maillet, Maël, Garnotel, Guillemette, Gauquelin-Koch, Audrey, Bergouignan, Stéphane, Blanc, Simon, Chantal, Département Ecologie, Physiologie et Ethologie (DEPE-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), University of Wisconsin-Madison, Institut de Médecine et de Physiologie Spatiales (MEDES), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université de Bordeaux (UB)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Université Jean Monnet - Saint-Étienne (UJM)-Université de Tours (UT)-Université de Clermont-Ferrand-Centre National d'Études Spatiales [Toulouse] (CNES), CADMOS-CNES, Centre National d’Études Spatiales [Paris] (CNES), University of Colorado [Denver], Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hospices Civils de Lyon (HCL), and Gaillard, Brigitte

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio]
Abstract

International audience; Objective: Body mass (BM) loss and body composition (BC) changes threaten astronauts' health and mission success. However, the energetics contribution of the exercise countermeasure to these changes has never been investigated during long-term missions. We studied energy balance and BC in astronauts during 6-month missions onboard the International Space Station. Methods: Before and after at least 3 months in space, BM, BC, total and activity energy expenditure (TEE and AEE) were measured using the doubly labeled water method in 11 astronauts (2011-2017). Physical activity (PA) was assessed by the SensewearPro® activity-device. Results: Three-month spaceflight decreased BM (-1.20kg (SE 0.5); P=0.04), mainly due to non-significant fat-free mass loss (FFM;-0.94kg (0.59)). The decrease in walking time (-63.2min/day (11.5); P

Published
2022
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8. Physiology of physical inactivity, sedentary behaviours and non‐exercise activity: insights from the space bedrest model.

Author

Le Roux, Elisa, De Jong, Nathan P., Blanc, Stéphane, Simon, Chantal, Bessesen, Daniel H., and Bergouignan, Audrey

Subjects
*SEDENTARY behavior, *PHYSICAL activity, *EXERCISE therapy, *SPACE sciences, *PHYSICALLY active people
Abstract

Physical inactivity, i.e. not reaching the recommended level of physical activity (PA), and sedentary behaviours (SB), i.e. sitting time, have been associated with increased risk for common metabolic diseases. Recent epidemiological data suggest that high volumes of SB are detrimental to metabolic health, even in the presence of regular exercise, i.e. moderate/vigorous PA. This suggests that the health effects of SB are independent from those of exercise. However, experimentally testing this hypothesis is complicated because of the difficulty in disassociating SB from PA. Bedrest studies, a traditional space science model, can offer new insights. In some bedrest studies, an exercise training protocol has been used to counteract the harmful effects of inactivity. While bedrest induces an inactive and sedentary state, exercise with bedrest represents a unique model of sedentary yet physically active people. Here, we review bedrest studies with and without exercise training. Although exercise training prevents the loss of muscle mass and function, even large volumes of exercise are not sufficient to fully counteract the negative metabolic adaptations triggered by inactivity. This observation supports the existence of independent adverse health effects of SB, but also the potential benefits of non‐exercise activity, i.e. daily living light PA. We gathered available data to examine the complex relationships between exercise, non‐exercise activity, SB and health outcomes. Given the large amount of SB in modern societies, the sole promotion of exercise, i.e. moderate/vigorous PA may be insufficient, and promotion of light PA may be a complimentary approach to improve health. [ABSTRACT FROM AUTHOR]

Published
2022
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