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4. Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility (Nature Genetics, (2022), 54, 3, (232-239), 10.1038/s41588-021-01007-6)

Author

Julien Barc, Barc, J, Tadros, R, Glinge, C, Chiang, D, Jouni, M, Simonet, F, Jurgens, S, Baudic, M, Nicastro, M, Potet, F, Offerhaus, J, Walsh, R, Hoan Choi, S, Verkerk, A, Mizusawa, Y, Anys, S, Minois, D, Arnaud, M, Duchateau, J, Wijeyeratne, Y, Muir, A, Papadakis, M, Castelletti, S, Torchio, M, Gil Ortuño, C, Lacunza, J, Giachino, D, Cerrato, N, Martins, R, Campuzano, O, Van Dooren, S, Thollet, A, Kyndt, F, Mazzanti, A, Clémenty, N, Bisson, A, Corveleyn, A, Stallmeyer, B, Dittmann, S, Saenen, J, Noël, A, Honarbakhsh, S, Rudic, B, Marzak, H, Rowe, M, Federspiel, C, Le Page, S, Placide, L, Milhem, A, Barajas-Martinez, H, Beckmann, B, Krapels, I, Steinfurt, J, Gregers Winkel, B, Jabbari, R, Shoemaker, M, Boukens, B, Škorić-Milosavljević, D, Bikker, H, Manevy, F, Lichtner, P, Ribasés, M, Meitinger, T, Müller-Nurasyid, M, Group, K, Veldink, J, van den Berg, L, Van Damme, P, Cusi, D, Lanzani, C, Rigade, S, Charpentier, E, Baron, E, Bonnaud, S, Lecointe, S, Donnart, A, Le Marec, H, Chatel, S, Karakachoff, M, Bézieau, S, London, B, Tfelt-Hansen, J, Roden, D, Odening, K, Cerrone, M, Chinitz, L, Volders, P, van de Berg, M, Laurent, G, Faivre, L, Antzelevitch, C, Kääb, S, Al Arnaout, A, Dupuis, J, Pasquie, J, Billon, O, Roberts, J, Jesel, L, Borggrefe, M, Lambiase, P, Mansourati, J, Loeys, B, Leenhardt, A, Guicheney, P, Maury, P, Schulze-Bahr, E, Robyns, T, Breckpot, J, Babuty, D, Priori, S, Napolitano, C, Referral Center for inherited cardiac arrhythmia, N, de Asmundis, C, Brugada, P, Brugada, R, Arbelo, E, Brugada, J, Mabo, P, Behar, N, Giustetto, C, Sabater Molina, M, Gimeno, J, Hasdemir, C, Schwartz, P, Crotti, L, Mckeown, P, Sharma, S, Behr, E, Haissaguerre, M, Sacher, F, Rooryck, C, Tan, H, Remme, C, Postema, P, Delmar, M, Ellinor, P, Lubitz, S, Gourraud, J, Tanck, M, L. George Jr., A, Macrae, C, Burridge, P, Dina, C, Probst, V, Wilde, A, Schott, J, Redon &amp, R, Bezzina, C, Julien Barc, Rafik Tadros, Charlotte Glinge, David Y. Chiang, Mariam Jouni, Floriane Simonet, Sean J. Jurgens, Manon Baudic, Michele Nicastro, Franck Potet, Joost A. Offerhaus, Roddy Walsh, Seung Hoan Choi, Arie O. Verkerk, Yuka Mizusawa, Soraya Anys, Damien Minois, Marine Arnaud, Josselin Duchateau, Yanushi D. Wijeyeratne, Alison Muir, Michael Papadakis, Silvia Castelletti, Margherita Torchio, Cristina Gil Ortuño, Javier Lacunza, Daniela F. Giachino, Natascia Cerrato, Raphaël P. Martins, Oscar Campuzano, Sonia Van Dooren, Aurélie Thollet, Florence Kyndt, Andrea Mazzanti, Nicolas Clémenty, Arnaud Bisson, Anniek Corveleyn, Birgit Stallmeyer, Sven Dittmann, Johan Saenen, Antoine Noël, Shohreh Honarbakhsh, Boris Rudic, Halim Marzak, Matthew K. Rowe, Claire Federspiel, Sophie Le Page, Leslie Placide, Antoine Milhem, Hector Barajas-Martinez, Britt-Maria Beckmann, Ingrid P. Krapels, Johannes Steinfurt, Bo Gregers Winkel, Reza Jabbari, Moore B. Shoemaker, Bas J. Boukens, Doris Škorić-Milosavljević, Hennie Bikker, Federico Manevy, Peter Lichtner, Marta Ribasés, Thomas Meitinger, Martina Müller-Nurasyid, KORA-Study Group, Jan H. Veldink, Leonard H. van den Berg, Philip Van Damme, Daniele Cusi, Chiara Lanzani, Sidwell Rigade, Eric Charpentier, Estelle Baron, Stéphanie Bonnaud, Simon Lecointe, Audrey Donnart, Hervé Le Marec, Stéphanie Chatel, Matilde Karakachoff, Stéphane Bézieau, Barry London, Jacob Tfelt-Hansen, Dan Roden, Katja E. Odening, Marina Cerrone, Larry A. Chinitz, Paul G. Volders, Maarten P. van de Berg, Gabriel Laurent, Laurence Faivre, Charles Antzelevitch, Stefan Kääb, Alain Al Arnaout, Jean-Marc Dupuis, Jean-Luc Pasquie, Olivier Billon, Jason D. Roberts, Laurence Jesel, Martin Borggrefe, Pier D. Lambiase, Jacques Mansourati, Bart Loeys, Antoine Leenhardt, Pascale Guicheney, Philippe Maury, Eric Schulze-Bahr, Tomas Robyns, Jeroen Breckpot, Dominique Babuty, Silvia G. Priori, Carlo Napolitano, Nantes Referral Center for inherited cardiac arrhythmia, Carlo de Asmundis, Pedro Brugada, Ramon Brugada, Elena Arbelo, Josep Brugada, Philippe Mabo, Nathalie Behar, Carla Giustetto, Maria Sabater Molina, Juan R. Gimeno, Can Hasdemir, Peter J. Schwartz, Lia Crotti, Pascal P. McKeown, Sanjay Sharma, Elijah R. Behr, Michel Haissaguerre, Frédéric Sacher, Caroline Rooryck, Hanno L. Tan, Carol A. Remme, Pieter G. Postema, Mario Delmar, Patrick T. Ellinor, Steven A. Lubitz, Jean-Baptiste Gourraud, Michael W. Tanck, Alfred L. George Jr., Calum A. MacRae, Paul W. Burridge, Christian Dina, Vincent Probst, Arthur A. Wilde, Jean-Jacques Schott, Richard Redon &, Connie R. Bezzina, Julien Barc, Barc, J, Tadros, R, Glinge, C, Chiang, D, Jouni, M, Simonet, F, Jurgens, S, Baudic, M, Nicastro, M, Potet, F, Offerhaus, J, Walsh, R, Hoan Choi, S, Verkerk, A, Mizusawa, Y, Anys, S, Minois, D, Arnaud, M, Duchateau, J, Wijeyeratne, Y, Muir, A, Papadakis, M, Castelletti, S, Torchio, M, Gil Ortuño, C, Lacunza, J, Giachino, D, Cerrato, N, Martins, R, Campuzano, O, Van Dooren, S, Thollet, A, Kyndt, F, Mazzanti, A, Clémenty, N, Bisson, A, Corveleyn, A, Stallmeyer, B, Dittmann, S, Saenen, J, Noël, A, Honarbakhsh, S, Rudic, B, Marzak, H, Rowe, M, Federspiel, C, Le Page, S, Placide, L, Milhem, A, Barajas-Martinez, H, Beckmann, B, Krapels, I, Steinfurt, J, Gregers Winkel, B, Jabbari, R, Shoemaker, M, Boukens, B, Škorić-Milosavljević, D, Bikker, H, Manevy, F, Lichtner, P, Ribasés, M, Meitinger, T, Müller-Nurasyid, M, Group, K, Veldink, J, van den Berg, L, Van Damme, P, Cusi, D, Lanzani, C, Rigade, S, Charpentier, E, Baron, E, Bonnaud, S, Lecointe, S, Donnart, A, Le Marec, H, Chatel, S, Karakachoff, M, Bézieau, S, London, B, Tfelt-Hansen, J, Roden, D, Odening, K, Cerrone, M, Chinitz, L, Volders, P, van de Berg, M, Laurent, G, Faivre, L, Antzelevitch, C, Kääb, S, Al Arnaout, A, Dupuis, J, Pasquie, J, Billon, O, Roberts, J, Jesel, L, Borggrefe, M, Lambiase, P, Mansourati, J, Loeys, B, Leenhardt, A, Guicheney, P, Maury, P, Schulze-Bahr, E, Robyns, T, Breckpot, J, Babuty, D, Priori, S, Napolitano, C, Referral Center for inherited cardiac arrhythmia, N, de Asmundis, C, Brugada, P, Brugada, R, Arbelo, E, Brugada, J, Mabo, P, Behar, N, Giustetto, C, Sabater Molina, M, Gimeno, J, Hasdemir, C, Schwartz, P, Crotti, L, Mckeown, P, Sharma, S, Behr, E, Haissaguerre, M, Sacher, F, Rooryck, C, Tan, H, Remme, C, Postema, P, Delmar, M, Ellinor, P, Lubitz, S, Gourraud, J, Tanck, M, L. George Jr., A, Macrae, C, Burridge, P, Dina, C, Probst, V, Wilde, A, Schott, J, Redon &amp, R, Bezzina, C, Julien Barc, Rafik Tadros, Charlotte Glinge, David Y. Chiang, Mariam Jouni, Floriane Simonet, Sean J. Jurgens, Manon Baudic, Michele Nicastro, Franck Potet, Joost A. Offerhaus, Roddy Walsh, Seung Hoan Choi, Arie O. Verkerk, Yuka Mizusawa, Soraya Anys, Damien Minois, Marine Arnaud, Josselin Duchateau, Yanushi D. Wijeyeratne, Alison Muir, Michael Papadakis, Silvia Castelletti, Margherita Torchio, Cristina Gil Ortuño, Javier Lacunza, Daniela F. Giachino, Natascia Cerrato, Raphaël P. Martins, Oscar Campuzano, Sonia Van Dooren, Aurélie Thollet, Florence Kyndt, Andrea Mazzanti, Nicolas Clémenty, Arnaud Bisson, Anniek Corveleyn, Birgit Stallmeyer, Sven Dittmann, Johan Saenen, Antoine Noël, Shohreh Honarbakhsh, Boris Rudic, Halim Marzak, Matthew K. Rowe, Claire Federspiel, Sophie Le Page, Leslie Placide, Antoine Milhem, Hector Barajas-Martinez, Britt-Maria Beckmann, Ingrid P. Krapels, Johannes Steinfurt, Bo Gregers Winkel, Reza Jabbari, Moore B. Shoemaker, Bas J. Boukens, Doris Škorić-Milosavljević, Hennie Bikker, Federico Manevy, Peter Lichtner, Marta Ribasés, Thomas Meitinger, Martina Müller-Nurasyid, KORA-Study Group, Jan H. Veldink, Leonard H. van den Berg, Philip Van Damme, Daniele Cusi, Chiara Lanzani, Sidwell Rigade, Eric Charpentier, Estelle Baron, Stéphanie Bonnaud, Simon Lecointe, Audrey Donnart, Hervé Le Marec, Stéphanie Chatel, Matilde Karakachoff, Stéphane Bézieau, Barry London, Jacob Tfelt-Hansen, Dan Roden, Katja E. Odening, Marina Cerrone, Larry A. Chinitz, Paul G. Volders, Maarten P. van de Berg, Gabriel Laurent, Laurence Faivre, Charles Antzelevitch, Stefan Kääb, Alain Al Arnaout, Jean-Marc Dupuis, Jean-Luc Pasquie, Olivier Billon, Jason D. Roberts, Laurence Jesel, Martin Borggrefe, Pier D. Lambiase, Jacques Mansourati, Bart Loeys, Antoine Leenhardt, Pascale Guicheney, Philippe Maury, Eric Schulze-Bahr, Tomas Robyns, Jeroen Breckpot, Dominique Babuty, Silvia G. Priori, Carlo Napolitano, Nantes Referral Center for inherited cardiac arrhythmia, Carlo de Asmundis, Pedro Brugada, Ramon Brugada, Elena Arbelo, Josep Brugada, Philippe Mabo, Nathalie Behar, Carla Giustetto, Maria Sabater Molina, Juan R. Gimeno, Can Hasdemir, Peter J. Schwartz, Lia Crotti, Pascal P. McKeown, Sanjay Sharma, Elijah R. Behr, Michel Haissaguerre, Frédéric Sacher, Caroline Rooryck, Hanno L. Tan, Carol A. Remme, Pieter G. Postema, Mario Delmar, Patrick T. Ellinor, Steven A. Lubitz, Jean-Baptiste Gourraud, Michael W. Tanck, Alfred L. George Jr., Calum A. MacRae, Paul W. Burridge, Christian Dina, Vincent Probst, Arthur A. Wilde, Jean-Jacques Schott, Richard Redon &, and Connie R. Bezzina

Abstract

In the version of this article initially published, Federico Manevy’s name appeared with a middle initial in error. The name has been corrected in the HTML and PDF versions of the article.

Published
2022

5. Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Author

Barc, J, Tadros, R, Glinge, C, Chiang, D, Jouni, M, Simonet, F, Jurgens, S, Baudic, M, Nicastro, M, Potet, F, Offerhaus, J, Walsh, R, Hoan Choi, S, Verkerk, A, Mizusawa, Y, Anys, S, Minois, D, Arnaud, M, Duchateau, J, Wijeyeratne, Y, Muir, A, Papadakis, M, Castelletti, S, Torchio, M, Gil Ortuño, C, Lacunza, J, Giachino, D, Cerrato, N, Martins, R, Campuzano, O, Van Dooren, S, Thollet, A, Kyndt, F, Mazzanti, A, Clémenty, N, Bisson, A, Corveleyn, A, Stallmeyer, B, Dittmann, S, Saenen, J, Noël, A, Honarbakhsh, S, Rudic, B, Marzak, H, Rowe, M, Federspiel, C, Le Page, S, Placide, L, Milhem, A, Barajas-Martinez, H, Beckmann, B, Krapels, I, Steinfurt, J, Gregers Winkel, B, Jabbari, R, Shoemaker, M, Boukens, B, Škorić-Milosavljević, D, Bikker, H, Manevy, F, Lichtner, P, Ribasés, M, Meitinger, T, Müller-Nurasyid, M, Group, K, Veldink, J, van den Berg, L, Van Damme, P, Cusi, D, Lanzani, C, Rigade, S, Charpentier, E, Baron, E, Bonnaud, S, Lecointe, S, Donnart, A, Le Marec, H, Chatel, S, Karakachoff, M, Bézieau, S, London, B, Tfelt-Hansen, J, Roden, D, Odening, K, Cerrone, M, Chinitz, L, Volders, P, van de Berg, M, Laurent, G, Faivre, L, Antzelevitch, C, Kääb, S, Al Arnaout, A, Dupuis, J, Pasquie, J, Billon, O, Roberts, J, Jesel, L, Borggrefe, M, Lambiase, P, Mansourati, J, Loeys, B, Leenhardt, A, Guicheney, P, Maury, P, Schulze-Bahr, E, Robyns, T, Breckpot, J, Babuty, D, Priori, S, Napolitano, C, Referral Center for inherited cardiac arrhythmia, N, de Asmundis, C, Brugada, P, Brugada, R, Arbelo, E, Brugada, J, Mabo, P, Behar, N, Giustetto, C, Sabater Molina, M, Gimeno, J, Hasdemir, C, Schwartz, P, Crotti, L, Mckeown, P, Sharma, S, Behr, E, Haissaguerre, M, Sacher, F, Rooryck, C, Tan, H, Remme, C, Postema, P, Delmar, M, Ellinor, P, Lubitz, S, Gourraud, J, Tanck, M, L. George Jr., A, Macrae, C, Burridge, P, Dina, C, Probst, V, Wilde, A, Schott, J, Redon &amp, R, Bezzina, C, Julien Barc, Rafik Tadros, Charlotte Glinge, David Y. Chiang, Mariam Jouni, Floriane Simonet, Sean J. Jurgens, Manon Baudic, Michele Nicastro, Franck Potet, Joost A. Offerhaus, Roddy Walsh, Seung Hoan Choi, Arie O. Verkerk, Yuka Mizusawa, Soraya Anys, Damien Minois, Marine Arnaud, Josselin Duchateau, Yanushi D. Wijeyeratne, Alison Muir, Michael Papadakis, Silvia Castelletti, Margherita Torchio, Cristina Gil Ortuño, Javier Lacunza, Daniela F. Giachino, Natascia Cerrato, Raphaël P. Martins, Oscar Campuzano, Sonia Van Dooren, Aurélie Thollet, Florence Kyndt, Andrea Mazzanti, Nicolas Clémenty, Arnaud Bisson, Anniek Corveleyn, Birgit Stallmeyer, Sven Dittmann, Johan Saenen, Antoine Noël, Shohreh Honarbakhsh, Boris Rudic, Halim Marzak, Matthew K. Rowe, Claire Federspiel, Sophie Le Page, Leslie Placide, Antoine Milhem, Hector Barajas-Martinez, Britt-Maria Beckmann, Ingrid P. Krapels, Johannes Steinfurt, Bo Gregers Winkel, Reza Jabbari, Moore B. Shoemaker, Bas J. Boukens, Doris Škorić-Milosavljević, Hennie Bikker, Federico Manevy, Peter Lichtner, Marta Ribasés, Thomas Meitinger, Martina Müller-Nurasyid, KORA-Study Group, Jan H. Veldink, Leonard H. van den Berg, Philip Van Damme, Daniele Cusi, Chiara Lanzani, Sidwell Rigade, Eric Charpentier, Estelle Baron, Stéphanie Bonnaud, Simon Lecointe, Audrey Donnart, Hervé Le Marec, Stéphanie Chatel, Matilde Karakachoff, Stéphane Bézieau, Barry London, Jacob Tfelt-Hansen, Dan Roden, Katja E. Odening, Marina Cerrone, Larry A. Chinitz, Paul G. Volders, Maarten P. van de Berg, Gabriel Laurent, Laurence Faivre, Charles Antzelevitch, Stefan Kääb, Alain Al Arnaout, Jean-Marc Dupuis, Jean-Luc Pasquie, Olivier Billon, Jason D. Roberts, Laurence Jesel, Martin Borggrefe, Pier D. Lambiase, Jacques Mansourati, Bart Loeys, Antoine Leenhardt, Pascale Guicheney, Philippe Maury, Eric Schulze-Bahr, Tomas Robyns, Jeroen Breckpot, Dominique Babuty, Silvia G. Priori, Carlo Napolitano, Nantes Referral Center for inherited cardiac arrhythmia, Carlo de Asmundis, Pedro Brugada, Ramon Brugada, Elena Arbelo, Josep Brugada, Philippe Mabo, Nathalie Behar, Carla Giustetto, Maria Sabater Molina, Juan R. Gimeno, Can Hasdemir, Peter J. Schwartz, Lia Crotti, Pascal P. McKeown, Sanjay Sharma, Elijah R. Behr, Michel Haissaguerre, Frédéric Sacher, Caroline Rooryck, Hanno L. Tan, Carol A. Remme, Pieter G. Postema, Mario Delmar, Patrick T. Ellinor, Steven A. Lubitz, Jean-Baptiste Gourraud, Michael W. Tanck, Alfred L. George Jr., Calum A. MacRae, Paul W. Burridge, Christian Dina, Vincent Probst, Arthur A. Wilde, Jean-Jacques Schott, Richard Redon &, Connie R. Bezzina, Barc, J, Tadros, R, Glinge, C, Chiang, D, Jouni, M, Simonet, F, Jurgens, S, Baudic, M, Nicastro, M, Potet, F, Offerhaus, J, Walsh, R, Hoan Choi, S, Verkerk, A, Mizusawa, Y, Anys, S, Minois, D, Arnaud, M, Duchateau, J, Wijeyeratne, Y, Muir, A, Papadakis, M, Castelletti, S, Torchio, M, Gil Ortuño, C, Lacunza, J, Giachino, D, Cerrato, N, Martins, R, Campuzano, O, Van Dooren, S, Thollet, A, Kyndt, F, Mazzanti, A, Clémenty, N, Bisson, A, Corveleyn, A, Stallmeyer, B, Dittmann, S, Saenen, J, Noël, A, Honarbakhsh, S, Rudic, B, Marzak, H, Rowe, M, Federspiel, C, Le Page, S, Placide, L, Milhem, A, Barajas-Martinez, H, Beckmann, B, Krapels, I, Steinfurt, J, Gregers Winkel, B, Jabbari, R, Shoemaker, M, Boukens, B, Škorić-Milosavljević, D, Bikker, H, Manevy, F, Lichtner, P, Ribasés, M, Meitinger, T, Müller-Nurasyid, M, Group, K, Veldink, J, van den Berg, L, Van Damme, P, Cusi, D, Lanzani, C, Rigade, S, Charpentier, E, Baron, E, Bonnaud, S, Lecointe, S, Donnart, A, Le Marec, H, Chatel, S, Karakachoff, M, Bézieau, S, London, B, Tfelt-Hansen, J, Roden, D, Odening, K, Cerrone, M, Chinitz, L, Volders, P, van de Berg, M, Laurent, G, Faivre, L, Antzelevitch, C, Kääb, S, Al Arnaout, A, Dupuis, J, Pasquie, J, Billon, O, Roberts, J, Jesel, L, Borggrefe, M, Lambiase, P, Mansourati, J, Loeys, B, Leenhardt, A, Guicheney, P, Maury, P, Schulze-Bahr, E, Robyns, T, Breckpot, J, Babuty, D, Priori, S, Napolitano, C, Referral Center for inherited cardiac arrhythmia, N, de Asmundis, C, Brugada, P, Brugada, R, Arbelo, E, Brugada, J, Mabo, P, Behar, N, Giustetto, C, Sabater Molina, M, Gimeno, J, Hasdemir, C, Schwartz, P, Crotti, L, Mckeown, P, Sharma, S, Behr, E, Haissaguerre, M, Sacher, F, Rooryck, C, Tan, H, Remme, C, Postema, P, Delmar, M, Ellinor, P, Lubitz, S, Gourraud, J, Tanck, M, L. George Jr., A, Macrae, C, Burridge, P, Dina, C, Probst, V, Wilde, A, Schott, J, Redon &amp, R, Bezzina, C, Julien Barc, Rafik Tadros, Charlotte Glinge, David Y. Chiang, Mariam Jouni, Floriane Simonet, Sean J. Jurgens, Manon Baudic, Michele Nicastro, Franck Potet, Joost A. Offerhaus, Roddy Walsh, Seung Hoan Choi, Arie O. Verkerk, Yuka Mizusawa, Soraya Anys, Damien Minois, Marine Arnaud, Josselin Duchateau, Yanushi D. Wijeyeratne, Alison Muir, Michael Papadakis, Silvia Castelletti, Margherita Torchio, Cristina Gil Ortuño, Javier Lacunza, Daniela F. Giachino, Natascia Cerrato, Raphaël P. Martins, Oscar Campuzano, Sonia Van Dooren, Aurélie Thollet, Florence Kyndt, Andrea Mazzanti, Nicolas Clémenty, Arnaud Bisson, Anniek Corveleyn, Birgit Stallmeyer, Sven Dittmann, Johan Saenen, Antoine Noël, Shohreh Honarbakhsh, Boris Rudic, Halim Marzak, Matthew K. Rowe, Claire Federspiel, Sophie Le Page, Leslie Placide, Antoine Milhem, Hector Barajas-Martinez, Britt-Maria Beckmann, Ingrid P. Krapels, Johannes Steinfurt, Bo Gregers Winkel, Reza Jabbari, Moore B. Shoemaker, Bas J. Boukens, Doris Škorić-Milosavljević, Hennie Bikker, Federico Manevy, Peter Lichtner, Marta Ribasés, Thomas Meitinger, Martina Müller-Nurasyid, KORA-Study Group, Jan H. Veldink, Leonard H. van den Berg, Philip Van Damme, Daniele Cusi, Chiara Lanzani, Sidwell Rigade, Eric Charpentier, Estelle Baron, Stéphanie Bonnaud, Simon Lecointe, Audrey Donnart, Hervé Le Marec, Stéphanie Chatel, Matilde Karakachoff, Stéphane Bézieau, Barry London, Jacob Tfelt-Hansen, Dan Roden, Katja E. Odening, Marina Cerrone, Larry A. Chinitz, Paul G. Volders, Maarten P. van de Berg, Gabriel Laurent, Laurence Faivre, Charles Antzelevitch, Stefan Kääb, Alain Al Arnaout, Jean-Marc Dupuis, Jean-Luc Pasquie, Olivier Billon, Jason D. Roberts, Laurence Jesel, Martin Borggrefe, Pier D. Lambiase, Jacques Mansourati, Bart Loeys, Antoine Leenhardt, Pascale Guicheney, Philippe Maury, Eric Schulze-Bahr, Tomas Robyns, Jeroen Breckpot, Dominique Babuty, Silvia G. Priori, Carlo Napolitano, Nantes Referral Center for inherited cardiac arrhythmia, Carlo de Asmundis, Pedro Brugada, Ramon Brugada, Elena Arbelo, Josep Brugada, Philippe Mabo, Nathalie Behar, Carla Giustetto, Maria Sabater Molina, Juan R. Gimeno, Can Hasdemir, Peter J. Schwartz, Lia Crotti, Pascal P. McKeown, Sanjay Sharma, Elijah R. Behr, Michel Haissaguerre, Frédéric Sacher, Caroline Rooryck, Hanno L. Tan, Carol A. Remme, Pieter G. Postema, Mario Delmar, Patrick T. Ellinor, Steven A. Lubitz, Jean-Baptiste Gourraud, Michael W. Tanck, Alfred L. George Jr., Calum A. MacRae, Paul W. Burridge, Christian Dina, Vincent Probst, Arthur A. Wilde, Jean-Jacques Schott, Richard Redon &, and Connie R. Bezzina

Abstract

Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in young adults. With the exception of SCN5A, encoding the cardiac sodium channel NaV1.5, susceptibility genes remain largely unknown. Here we performed a genome-wide association meta-analysis comprising 2,820 unrelated cases with BrS and 10,001 controls, and identified 21 association signals at 12 loci (10 new). Single nucleotide polymorphism (SNP)-heritability estimates indicate a strong polygenic influence. Polygenic risk score analyses based on the 21 susceptibility variants demonstrate varying cumulative contribution of common risk alleles among different patient subgroups, as well as genetic associations with cardiac electrical traits and disorders in the general population. The predominance of cardiac transcription factor loci indicates that transcriptional regulation is a key feature of BrS pathogenesis. Furthermore, functional studies conducted on MAPRE2, encoding the microtubule plus-end binding protein EB2, point to microtubule-related trafficking effects on NaV1.5 expression as a new underlying molecular mechanism. Taken together, these findings broaden our understanding of the genetic architecture of BrS and provide new insights into its molecular underpinnings.

Published
2022

15. P2864A novel mechanism of sinus node dysfunction: intergenic deletion between PITX2 and ANK2 disrupts chromatin structure in pacemaker cell differentiation

Author

Murata, H, primary, Lindenbaum, P, additional, Le Scouarnec, S, additional, Baron, E, additional, Rajalu, A, additional, Kyndt, F, additional, Deleuze, J F, additional, Le Marec, H, additional, Probst, V, additional, Shimizu, W, additional, Redon, R, additional, and Schott, J J, additional

Published
2019
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17. P5441Aortic valve phenotype associated with filamin-A mutations: a comprehensive echocardiographic and outcomes analyses

Author

Capoulade, R, primary, Cueff, C, additional, Piriou, N, additional, Toquet, C, additional, Blandin, S, additional, Guimbretiere, G, additional, Omen, T, additional, Aalberts, J, additional, Bernstein, D, additional, Bernstein, J, additional, Trochu, J N, additional, Le Marec, H, additional, Merot, J, additional, Schott, J J, additional, and Le Tourneau, T, additional

Published
2018
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18. SCN5A mutations in 442 neonates and children: genotype-phenotype correlation and identification of higher-risk subgroups.

Author

Baruteau, A, Kyndt, F, Behr, E, Vink, A, Lachaud, M, Joong, A, Schott, J, Horie, M, Denjoy, I, Crotti, L, Shimizu, W, Bos, J, Stephenson, E, Wong, L, Abrams, D, Davis, A, Winbo, A, Dubin, A, Sanatani, S, Liberman, L, Kaski, J, Rudic, B, Kwok, S, Rieubland, C, Tfelt-Hansen, J, Van Hare, G, Guyomarc'h-Delasalle, B, Blom, N, Wijeyeratne, Y, Gourraud, J, Le Marec, H, Ozawa, J, Fressart, V, Lupoglazoff, J, Dagradi, F, Spazzolini, C, Aiba, T, Tester, D, Zahavich, L, Beauséjour-Ladouceur, V, Jadhav, M, Skinner, J, Franciosi, S, Krahn, A, Abdelsayed, M, Ruben, P, Yung, T, Ackerman, M, Wilde, A, Schwartz, P, Probst, V, Baruteau, AE, Behr, ER, Vink, AS, Schott, JJ, Bos, JM, Stephenson, EA, Abrams, DJ, Davis, AM, Dubin, AM, Kaski, JP, Kwok, SY, Van Hare, GF, Blom, NA, Wijeyeratne, YD, Gourraud, JB, Lupoglazoff, JM, Tester, DJ, Zahavich, LA, Skinner, JR, Krahn, AD, Ruben, PC, Yung, TC, Ackerman, MJ, Wilde, AA, Schwartz, PJ, Probst, V., Baruteau, A, Kyndt, F, Behr, E, Vink, A, Lachaud, M, Joong, A, Schott, J, Horie, M, Denjoy, I, Crotti, L, Shimizu, W, Bos, J, Stephenson, E, Wong, L, Abrams, D, Davis, A, Winbo, A, Dubin, A, Sanatani, S, Liberman, L, Kaski, J, Rudic, B, Kwok, S, Rieubland, C, Tfelt-Hansen, J, Van Hare, G, Guyomarc'h-Delasalle, B, Blom, N, Wijeyeratne, Y, Gourraud, J, Le Marec, H, Ozawa, J, Fressart, V, Lupoglazoff, J, Dagradi, F, Spazzolini, C, Aiba, T, Tester, D, Zahavich, L, Beauséjour-Ladouceur, V, Jadhav, M, Skinner, J, Franciosi, S, Krahn, A, Abdelsayed, M, Ruben, P, Yung, T, Ackerman, M, Wilde, A, Schwartz, P, Probst, V, Baruteau, AE, Behr, ER, Vink, AS, Schott, JJ, Bos, JM, Stephenson, EA, Abrams, DJ, Davis, AM, Dubin, AM, Kaski, JP, Kwok, SY, Van Hare, GF, Blom, NA, Wijeyeratne, YD, Gourraud, JB, Lupoglazoff, JM, Tester, DJ, Zahavich, LA, Skinner, JR, Krahn, AD, Ruben, PC, Yung, TC, Ackerman, MJ, Wilde, AA, Schwartz, PJ, and Probst, V.

Abstract

Aims: To clarify the clinical characteristics and outcomes of children with SCN5A-mediated disease and to improve theirrisk stratification. Methods and results: A multicentre, international, retrospective cohort study was conducted in 25 tertiary hospitals in 13 countries between1990 and 2015. All patients <_16 years of age diagnosed with a genetically confirmed SCN5A mutation wereincluded in the analysis. There was no restriction made based on their clinical diagnosis. A total of 442 children{55.7% boys, 40.3% probands, median age: 8.0 [interquartile range (IQR) 9.5] years} from 350 families wereincluded; 67.9% were asymptomatic at diagnosis. Four main phenotypes were identified: isolated progressive cardiacconduction disorders (25.6%), overlap phenotype (15.6%), isolated long QT syndrome type 3 (10.6%), and isolatedBrugada syndrome type 1 (1.8%); 44.3% had a negative electrocardiogram phenotype. During a medianfollow-up of 5.9 (IQR 5.9) years, 272 cardiac events (CEs) occurred in 139 (31.5%) patients. Patients whose mutationlocalized in the C-terminus had a lower risk. Compound genotype, both gain- and loss-of-function SCN5A mutation,age <_1 year at diagnosis in probands and age <_1 year at diagnosis in non-probands were independent predictorsof CE.Conclusion In this large paediatric cohort of SCN5A mutation-positive subjects, cardiac conduction disorders were the mostprevalent phenotype; CEs occurred in about one-third of genotype-positive children, and several independent riskfactors were identified, including age <_1 year at diagnosis, compound mutation, and mutation with both gain- andloss-of-function.

Published
2018

19. Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Author

Bezzina, C, Barc, J, Mizusawa, Y, Remme, C, Gourraud, J, Simonet, F, Verkerk, A, Schwartz, P, Crotti, L, Dagradi, F, Guicheney, P, Fressart, V, Leenhardt, A, Antzelevitch, C, Bartkowiak, S, Borggrefe, M, Schimpf, R, Schulze-Bahr, E, Zumhagen, S, Behr, E, Bastiaenen, R, Tfelt-Hansen, J, Olesen, M, Kääb, S, Beckmann, B, Weeke, P, Watanabe, H, Endo, N, Minamino, T, Horie, M, Ohno, S, Hasegawa, K, Makita, N, Nogami, A, Shimizu, W, Aiba, T, Froguel, P, Balkau, B, Lantieri, O, Torchio, M, Wiese, C, Weber, D, Wolswinkel, R, Coronel, R, Boukens, B, Bézieau, S, Charpentier, E, Chatel, S, Despres, A, Gros, F, Kyndt, F, Lecointe, S, Lindenbaum, P, Portero, V, Violleau, J, Gessler, M, Tan, H, Roden, D, Christoffels, V, Le Marec, H, Wilde, A, Probst, V, Schott, J, Dina, C, Redon, R, Bezzina CR., Barc J., Mizusawa Y., Remme CA., Gourraud JB., Simonet F., Verkerk AO., Schwartz PJ., Crotti L., Dagradi F., Guicheney P., Fressart V., Leenhardt A., Antzelevitch C., Bartkowiak S., Borggrefe M., Schimpf R., Schulze-Bahr E., Zumhagen S., Behr ER., Bastiaenen R., Tfelt-Hansen J., Olesen MS., Kääb S., Beckmann BM., Weeke P., Watanabe H., Endo N., Minamino T., Horie M., Ohno S., Hasegawa K., Makita N., Nogami A., Shimizu W., Aiba T., Froguel P., Balkau B., Lantieri O., Torchio M., Wiese C., Weber D., Wolswinkel R., Coronel R., Boukens BJ., Bézieau S., Charpentier E., Chatel S., Despres A., Gros F., Kyndt F., Lecointe S., Lindenbaum P., Portero V., Violleau J., Gessler M., Tan HL., Roden DM., Christoffels VM., Le Marec H., Wilde AA., Probst V., Schott JJ., Dina C., Redon R., Bezzina, C, Barc, J, Mizusawa, Y, Remme, C, Gourraud, J, Simonet, F, Verkerk, A, Schwartz, P, Crotti, L, Dagradi, F, Guicheney, P, Fressart, V, Leenhardt, A, Antzelevitch, C, Bartkowiak, S, Borggrefe, M, Schimpf, R, Schulze-Bahr, E, Zumhagen, S, Behr, E, Bastiaenen, R, Tfelt-Hansen, J, Olesen, M, Kääb, S, Beckmann, B, Weeke, P, Watanabe, H, Endo, N, Minamino, T, Horie, M, Ohno, S, Hasegawa, K, Makita, N, Nogami, A, Shimizu, W, Aiba, T, Froguel, P, Balkau, B, Lantieri, O, Torchio, M, Wiese, C, Weber, D, Wolswinkel, R, Coronel, R, Boukens, B, Bézieau, S, Charpentier, E, Chatel, S, Despres, A, Gros, F, Kyndt, F, Lecointe, S, Lindenbaum, P, Portero, V, Violleau, J, Gessler, M, Tan, H, Roden, D, Christoffels, V, Le Marec, H, Wilde, A, Probst, V, Schott, J, Dina, C, Redon, R, Bezzina CR., Barc J., Mizusawa Y., Remme CA., Gourraud JB., Simonet F., Verkerk AO., Schwartz PJ., Crotti L., Dagradi F., Guicheney P., Fressart V., Leenhardt A., Antzelevitch C., Bartkowiak S., Borggrefe M., Schimpf R., Schulze-Bahr E., Zumhagen S., Behr ER., Bastiaenen R., Tfelt-Hansen J., Olesen MS., Kääb S., Beckmann BM., Weeke P., Watanabe H., Endo N., Minamino T., Horie M., Ohno S., Hasegawa K., Makita N., Nogami A., Shimizu W., Aiba T., Froguel P., Balkau B., Lantieri O., Torchio M., Wiese C., Weber D., Wolswinkel R., Coronel R., Boukens BJ., Bézieau S., Charpentier E., Chatel S., Despres A., Gros F., Kyndt F., Lecointe S., Lindenbaum P., Portero V., Violleau J., Gessler M., Tan HL., Roden DM., Christoffels VM., Le Marec H., Wilde AA., Probst V., Schott JJ., Dina C., and Redon R.

Abstract

Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A mutations in around 20% of cases. Through a genome-wide association study of 312 individuals with Brugada syndrome and 1,115 controls, we detected 2 significant association signals at the SCN10A locus (rs10428132) and near the HEY2 gene (rs9388451). Independent replication confirmed both signals (meta-analyses: rs10428132, P = 1.0 × 10 -68; rs9388451, P = 5.1 × 10 -17) and identified one additional signal in SCN5A (at 3p21; rs11708996, P = 1.0 × 10 -14). The cumulative effect of the three loci on disease susceptibility was unexpectedly large (P trend = 6.1 × 10 -81). The association signals at SCN5A-SCN10A demonstrate that genetic polymorphisms modulating cardiac conduction can also influence susceptibility to cardiac arrhythmia. The implication of association with HEY2, supported by new evidence that Hey2 regulates cardiac electrical activity, shows that Brugada syndrome may originate from altered transcriptional programming during cardiac development. Altogether, our findings indicate that common genetic variation can have a strong impact on the predisposition to rare diseases

Published
2013

21. Young Investigator Award session – Clinical Science442Left bundle branch block and coronary artery disease in coronary ct angiography443Focal myocardial fibrosis and abnormal left ventricular strain in patients with sarcoidosis without clinical evidence of cardiac disease444Arhgap24, a first gene for fibro elastic deficiency mitral valve prolapse? A phenotypic study445Advantage of using ASE/EACVI criteria for detection of subclinical cardiotoxicity in breast cancer patients undergoing anthracycline and trastuzumab therapy

Author

Clerc, O F, primary, Lima Da Silva, G, primary, Jobbe Duval, A, primary, Santoro, C, primary, Possner, M, additional, Liga, R, additional, Fuchs, T A, additional, Dougoud, S, additional, Stehli, J, additional, Vontobel, J, additional, Mikulicic, F, additional, Kaufmann, P A, additional, Gaemperli, O, additional, Almeida, A M G, additional, David, C, additional, Francisco, AR, additional, Guimaraes, T, additional, Placido, R, additional, Menezes, M, additional, Pinto, FJ, additional, Rimbert, A, additional, Cueff, C, additional, Lecointe, S, additional, Hagege, AA, additional, Levine, R, additional, Merot, J, additional, Le Marec, H, additional, Schott, JJ, additional, Le Tourneau, T, additional, Lembo, M, additional, Esposito, R, additional, Cocozza, S, additional, Ilardi, F, additional, Arpino, G, additional, De Placido, S, additional, De Simone, G, additional, Trimarco, B, additional, and Galderisi, M, additional

Published
2015
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22. MIBG Scintigraphy of a Patient with Pheochromocytoma on Labetalol Therapy

Author

A. Chetanneau, Bardies M, Le Marec H, Chatal Jf, M. Kremer, J. Morais, and Peltier P

Subjects
Adult, Male, medicine.medical_specialty, Adrenal Gland Neoplasms, Pheochromocytoma, Scintigraphy, Iodine Radioisotopes, Text mining, Internal medicine, Humans, Medicine, Labetalol, Radiology, Nuclear Medicine and imaging, Radionuclide Imaging, medicine.diagnostic_test, Iodobenzenes, business.industry, Imaging study, General Medicine, medicine.disease, 3-Iodobenzylguanidine, Endocrinology, Serial imaging, business, Nuclear medicine, medicine.drug
Abstract

A patient with pheochromocytoma was studied by MIBG scintigraphy while on labetalol therapy, which has been reported to interfere with imaging. Serial imaging was performed at 2, 18, 25, and 90 hours to obtain time/activity curves. Blood samples were taken at each imaging study to determine activity counts. Tumor activity per gram of tissue (surgery 116 hours after injection) was compared with blood activity. Tumor and blood activity decreased concurrently, whereas the decrease in peritumoral activity was faster, thus providing transiently improved contrast on 18- and 25-hour images. The diagnostic implications of these results are discussed.

Published
1992
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23. Brugada syndrome: overview

Author

Antzelevitch, C., Brugada, P., Borggrefe, M., Brugada, J., Brugada, R., Corrado, D., Gussak, I., Le Marec, H., Nademanee, K., Perez Riera, A. R., Tan, H. [=Hanno L.], Shimizu, W., Schulze-Bahr, E., Wilde, A. A. M., Amsterdam Cardiovascular Sciences, and Cardiology

Published
2005

24. Brugada Syndrome: Overview

Author

Antzelevitch, C., primary, Brugada, P., additional, Borggrefe, M., additional, Brugada, J., additional, Brugada, R., additional, Corrado, D., additional, Gussak, I., additional, Le Marec, H., additional, Nademanee, K., additional, Perez Riera, A. R., additional, Tan, H., additional, Shimizu, W., additional, Schulze-Bahr, E., additional, and Wilde, A. A. M., additional

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26. GAIN-OF-FUNCTION MUTATION IN THE VOLTAGE-GATED K+ CHANNEL BETA-2 SUBUNIT IS ASSOCIATED WITH BRUGADA SYNDROME

Author

Portero, V., primary, Le Scouarnec, S., additional, Es-Salah-Lamoureux, Z., additional, Burel, S., additional, Gourraud, J., additional, Bonnaud, S., additional, Lindenbaum, P., additional, Simonet, F., additional, Violleau, J., additional, Sandoval-Tortosa, J., additional, Scott, C., additional, Chatel, S., additional, Loussouarn, G., additional, O’Hara, T., additional, Mabo, P., additional, Dina, C., additional, Le Marec, H., additional, Schott, J., additional, Probst, V., additional, Baró, I., additional, Marionneau, C., additional, Charpentier, F., additional, and Redon, R., additional

Published
2014
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29. Cardiac characteristics and long-term outcome in Andersen-Tawil syndrome patients related to KCNJ2 mutation

Author

Delannoy, E., primary, Sacher, F., additional, Maury, P., additional, Mabo, P., additional, Mansourati, J., additional, Magnin, I., additional, Camous, J.-P., additional, Tournant, G., additional, Rendu, E., additional, Kyndt, F., additional, Haissaguerre, M., additional, Bezieau, S., additional, Guyomarch, B., additional, Le Marec, H., additional, Fressart, V., additional, Denjoy, I., additional, and Probst, V., additional

Published
2013
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30. Corrigendum to: 'HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies' [Europace 2011;13:1077-109, doi: 10.1093/europace/eur245]

Author

Ackerman, M. J., primary, Priori, S. G., additional, Willems, S., additional, Berul, C., additional, Brugada, R., additional, Calkins, H., additional, Camm, A. J., additional, Ellinor, P. T., additional, Gollob, M., additional, Hamilton, R., additional, Hershberger, R. E., additional, Judge, D. P., additional, Le Marec, H., additional, McKenna, W. J., additional, Schulze-Bahr, E., additional, Semsarian, C., additional, Towbin, J. A., additional, Watkins, H., additional, Wilde, A., additional, Wolpert, C., additional, and Zipes, D. P., additional

Published
2012
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31. Characteristics and long-term outcome of non-immune isolated atrioventricular block diagnosed in utero or early childhood: a multicentre study

Author

Baruteau, A.-E., primary, Fouchard, S., additional, Behaghel, A., additional, Mabo, P., additional, Villain, E., additional, Thambo, J.-B., additional, Marcon, F., additional, Gournay, V., additional, Rouault, F., additional, Chantepie, A., additional, Guillaumont, S., additional, Godart, F., additional, Bonnet, C., additional, Fraisse, A., additional, Schleich, J.-M., additional, Lusson, J.-R., additional, Dulac, Y., additional, Leclercq, C., additional, Daubert, J.-C., additional, Schott, J.-J., additional, Le Marec, H., additional, and Probst, V., additional

Published
2011
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32. HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies: This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)

Author

Ackerman, M. J., primary, Priori, S. G., additional, Willems, S., additional, Berul, C., additional, Brugada, R., additional, Calkins, H., additional, Camm, A. J., additional, Ellinor, P. T., additional, Gollob, M., additional, Hamilton, R., additional, Hershberger, R. E., additional, Judge, D. P., additional, Le Marec, H., additional, McKenna, W. J., additional, Schulze-Bahr, E., additional, Semsarian, C., additional, Towbin, J. A., additional, Watkins, H., additional, Wilde, A., additional, Wolpert, C., additional, and Zipes, D. P., additional

Published
2011
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33. Poster Session 4

Author

Tada, H., primary, Yamasaki, H., additional, Sekiguchi, Y., additional, Igarashi, M., additional, Kuroki, K., additional, Machino, T., additional, Yoshida, K., additional, Aonuma, K., additional, Heinzel, F. R., additional, Forstner, H., additional, Lercher, P., additional, Bisping, E., additional, Rotman, B., additional, Fruhwald, F. M., additional, Pieske, B. M., additional, Dabrowski, R., additional, Kowalik, I., additional, Borowiec, A., additional, Smolis-Bak, E., additional, Trybuch, A., additional, Sosnowski, C., additional, Szwed, H., additional, Baturova, M. A., additional, Lindgren, A., additional, Shubik, Y. V., additional, Olsson, B., additional, Platonov, P. G., additional, Van Den Broek, K. C., additional, Denollet, J., additional, Widdershoven, J., additional, Kupper, N., additional, Allam, R., additional, Allam, R. A. G. A. B., additional, Galal, W. A. G. D. Y., additional, El-Damnhoury, H. A. Y. A. M., additional, Mortada, A. Y. M. A. N., additional, Jimenez-Candil, J., additional, Martin, A., additional, Hernandez, J., additional, Martin, F., additional, Gallego, M., additional, Martin-Luengo, C., additional, Quintanilla, J. G., additional, Moreno Planas, J., additional, Molina-Morua, R., additional, Archondo, T., additional, Garcia-Torrent, M. J., additional, Perez-Castellano, N., additional, Macaya, C., additional, Perez-Villacastin, J., additional, Saiz, J., additional, Tobon, C., additional, Rodriguez, J. F., additional, Hornero, F., additional, Ferrero, J. M., additional, Ito, K., additional, Date, T., additional, Kawai, M., additional, Hioki, M., additional, Narui, R., additional, Matsuo, S., additional, Yoshimura, M., additional, Yamane, T., additional, Tabatabaei, N., additional, Lin, G., additional, Powell, B. D., additional, Smairat, R., additional, Glockner, J. F., additional, Brady, P. A., additional, Fichtner, S., additional, Czudnochowsky, U., additional, Estner, H., additional, Reents, T., additional, Jilek, C., additional, Ammar, S., additional, Hessling, G., additional, Deisenhofer, I., additional, Shah, D. C., additional, Kautzner, J., additional, Saoudi, N., additional, Herrera, C., additional, Jais, P., additional, Hindricks, G., additional, Neuzil, P., additional, Kuck, K. H., additional, Wong, K. C. K., additional, Jones, M., additional, Qureshi, N., additional, Muthumala, A., additional, Betts, T. R., additional, Bashir, Y., additional, Rajappan, K., additional, Vogtmann, T., additional, Wagner, M., additional, Schurig, J., additional, Hein, P., additional, Hamm, B., additional, Baumann, G., additional, Lembcke, A., additional, Saad, B., additional, Slater, C., additional, Oliveira, L. A., additional, Elias, R., additional, Camiletti, A., additional, Moura, D., additional, Maldonado, P., additional, Camanho, L. E., additional, Bulava, A., additional, Hanis, J., additional, Sitek, D., additional, Novotny, A., additional, Chik, W. B., additional, Lim, T. W., additional, Choon, H. K., additional, See, V. A., additional, Mccall, R., additional, Thomas, L., additional, Ross, D. L., additional, Thomas, S. P., additional, Chen, J., additional, De Bortoli, A., additional, Rossvoll, O., additional, Hoff, P. I., additional, Solheim, E., additional, Sun, L. Z., additional, Schuster, P., additional, Ohm, O. J., additional, Ardashev, A. V., additional, Zhelyakov, E., additional, Rybachenko, M. S., additional, Konev, A. V., additional, Belenkov, Y. U. N., additional, Gunawardene, M., additional, Chun, K. R. J., additional, Schulte-Hahn, B., additional, Windhorst, V., additional, Kulikoglu, M., additional, Nowak, B., additional, Schmidt, B., additional, Albina, G. A., additional, Rivera, R. S., additional, Scazzuso, F., additional, Laino, R. L., additional, Giniger, G. A., additional, Arbelo, E., additional, Calvo, N., additional, Tamborero, D., additional, Andreu, D., additional, Borras, R., additional, Berruezo, A., additional, Brugada, J., additional, Mont, L., additional, Stefan, L., additional, Eisenberger, M., additional, Celentano, E., additional, Peytchev, P., additional, Bodea, O., additional, Geelen, P., additional, De Potter, T., additional, Oliveira, M. M., additional, Silva, N., additional, Cunha, P. S., additional, Feliciano, J., additional, Lousinha, A., additional, Toste, A., additional, Santos, S., additional, Ferreira, R. C., additional, Matsuda, H., additional, Harada, T., additional, Soejima, K., additional, Ishikawa, Y., additional, Mizukoshi, K., additional, Sasaki, T., additional, Mizuno, K., additional, Miyake, F., additional, Adragao, P. P., additional, Cavaco, D., additional, Miranda, R., additional, Santos, M., additional, Morgado, F., additional, Reis Santos, K., additional, Candeias, R., additional, Marcelino, S., additional, Zoppo, F., additional, Grandolino, G., additional, Zerbo, F., additional, Bertaglia, E., additional, Schlueter, S. M., additional, Grebe, O., additional, Vester, E. G., additional, Miracle Blanco, A. L., additional, Arenal Maiz, A., additional, Atienza Fernandez, F., additional, Datino Romaniega, T., additional, Gonzalez Torrecilla, E., additional, Eidelman, G., additional, Hernandez Hernandez, J., additional, Fernandez Aviles, F., additional, Fukumoto, K., additional, Takatsuki, S., additional, Kimura, T., additional, Nishiyama, N., additional, Aizawa, Y., additional, Sato, T., additional, Miyoshi, S., additional, Fukuda, K., additional, Richter, B., additional, Gwechenberger, M., additional, Socas, A., additional, Zorn, G., additional, Albinni, S., additional, Marx, M., additional, Wojta, J., additional, Goessinger, H., additional, Deneke, T., additional, Balta, O., additional, Paesler, M., additional, Buenz, K., additional, Anders, H., additional, Horlitz, M., additional, Muegge, A., additional, Shin, D.- I., additional, Natsuyama, K., additional, Yamaguchi, K. M., additional, Nishida, Y. N., additional, Kosiuk, J., additional, Bode, K., additional, Arya, A., additional, Piorkowski, C., additional, Gaspar, T., additional, Sommer, P., additional, Bollmann, A., additional, Wichterle, D., additional, Peichl, P., additional, Simek, J., additional, Havranek, S., additional, Bulkova, V., additional, Cihak, R., additional, Jurado Roman, A., additional, Salguero Bodes, R., additional, Lopez Gil, M., additional, Fontenla Cerezuela, A., additional, De Riva Silva, M., additional, Arribas Ynsaurriaga, F., additional, Fernandez Herranz, A. I., additional, De Dios Perez, S., additional, Revishvili, A. S., additional, Dishekov, M., additional, Tembotova, Z., additional, Barsamyan, S., additional, Vaccari, D., additional, Alvarenga, C., additional, Jesus, I., additional, Layher, J., additional, Takahashi, A., additional, Singh, N., additional, Siot, P., additional, Elkaim, J. P., additional, Savelieva, I., additional, Mcclelland, L., additional, Lovegrove, A., additional, Jones, S., additional, Camm, J., additional, Folino, A. F., additional, Breda, R., additional, Calzavara, P., additional, Comisso, J., additional, Borghetti, F., additional, Iliceto, S., additional, Buja, G., additional, Mlynarski, R., additional, Mlynarska, A., additional, Sosnowski, M., additional, Wilczek, J., additional, Mabo, P., additional, Carrault, G., additional, Bordachar, P., additional, Makdissi, A., additional, Duchemin, L., additional, Alonso, C., additional, Neri, G., additional, Masaro, G., additional, Vittadello, S., additional, Gardin, A., additional, Barbetta, A., additional, Di Gregorio, F., additional, Sciaraffia, E., additional, Ginks, M. R., additional, Gustafsson, J. S., additional, Hollmark, M. C., additional, Rinaldi, C. A., additional, Blomstrom Lundqvist, C., additional, Brusich, S., additional, Tomasic, D., additional, Ferek-Petric, B., additional, Mavric, Z., additional, Kutarski, A., additional, Malecka, B., additional, Kolodzinska, A., additional, Grabowski, M., additional, Dovellini, E. V., additional, Giurlani, L., additional, Cerisano, G., additional, Carrabba, N., additional, Valenti, R., additional, Antoniucci, D., additional, Opolski, G., additional, Tomassoni, G., additional, Baker, J., additional, Corbisiero, R., additional, Martin, D., additional, Niazi, I., additional, Sheppard, R., additional, Sperzel, J., additional, Gutleben, K., additional, Petru, J., additional, Sediva, L., additional, Skoda, J., additional, Mazzone, P., additional, Ciconte, G., additional, Vergara, P., additional, Marzi, A., additional, Paglino, G., additional, Sora, N., additional, Gulletta, S., additional, Della Bella, P., additional, Pietura, R., additional, Czajkowski, M., additional, Cabanelas, N., additional, Martins, V. P., additional, Alves, M., additional, Valente, F. X., additional, Marta, L., additional, Francisco, A., additional, Silva, R., additional, Ferreira Da Silva, G., additional, Huo, Y., additional, Holmqvist, F., additional, Carlson, J., additional, Wetzel, U., additional, Platonov, P., additional, Nof, E., additional, Abu Shama, R., additional, Kuperstein, R., additional, Feinberg, M. S., additional, Eldar, M., additional, Glikson, M., additional, Luria, D., additional, Kubus, P., additional, Materna, O., additional, Gebauer, R. A., additional, Matejka, T., additional, Gebauer, R., additional, Tlaskal, T., additional, Janousek, J., additional, Muessigbrodt, A., additional, Richter, S., additional, Stockburger, M., additional, Boveda, S., additional, Defaye, P., additional, Stancak Branislav, P., additional, Kaliska, G., additional, Rolando, M., additional, Moreno, J., additional, Ohlow, M.- A. G., additional, Lauer, B., additional, Buchter, B., additional, Schreiber, M., additional, Geller, J. C., additional, Val-Mejias, J. E., additional, Ouali, S., additional, Azzez, S., additional, Kacem, S., additional, Ben Salem, H., additional, Hammas, S., additional, Neffeti, E., additional, Remedi, F., additional, Boughzela, E., additional, Miyazaki, H., additional, Miyanaga, S., additional, Shibayama, K., additional, Tokuda, M., additional, Kudo, T., additional, Coppola, B., additional, Shehada, R. E. N., additional, Costandi, P., additional, Healey, J., additional, Hohnloser, S. H., additional, Gold, M. R., additional, Capucci, A., additional, Van Gelder, I. C., additional, Carlson, M., additional, Lau, C. P., additional, Connolly, S. J., additional, Bogaard, M. D., additional, Leenders, G. E., additional, Maskara, B., additional, Tuinenburg, A. E., additional, Loh, P., additional, Hauer, R. N., additional, Doevendans, P. 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R., additional, Delarche, N., additional, Bizeau, O., additional, Couderc, P., additional, Chapelet, A., additional, Amara, W., additional, Lazarus, A., additional, Krupickova, S., additional, Van Deursen, C. J. M., additional, Strik, M., additional, Vernooy, K., additional, Van Hunnik, A., additional, Kuiper, M., additional, Crijns, H. J. G. M., additional, Prinzen, F. W., additional, Islam, N., additional, Gras, D., additional, Abraham, W., additional, Calo, L., additional, Birgersdotter-Green, U., additional, Clyne, C., additional, Herre, J., additional, Klein, N., additional, Kowalski, O., additional, Lenarczyk, R., additional, Pruszkowska, P., additional, Sokal, A., additional, Kukulski, T., additional, Zielinska, T., additional, Pluta, S., additional, Kalarus, Z., additional, Schwab, J. O., additional, Gasparini, M., additional, Anselme, F., additional, Clementy, J., additional, Santini, M., additional, Martinez Ferrer, J., additional, Burrone, V., additional, Santi, E., additional, Nevzorov, R., additional, Porter, A., additional, Kusniec, J., additional, Golovchiner, G., additional, Ben-Gal, T., additional, Strasberg, B., additional, Haim, M., additional, Rordorf, R., additional, Savastano, S., additional, Sanzo, A., additional, Vicentini, A., additional, Petracci, B., additional, De Amici, M., additional, Striuli, L., additional, Landolina, M., additional, Tolosana, J. M., additional, Martin, A. M., additional, Hernandez-Madrid, A., additional, Macias, A., additional, Fernandez-Lozano, I., additional, Osca, J., additional, Quesada, A., additional, Tada, H., additional, Noguchi, Y., additional, Shahrzad, S., additional, Karim Soleiman, N., additional, Tavoosi, A., additional, Taban, S., additional, Emkanjoo, Z., additional, Fukunaga, M., additional, Goya, M., additional, Hiroshima, K., additional, Ohe, M., additional, Hayashi, K., additional, Iwabuchi, M., additional, Nosaka, H., additional, Nobuyoshi, M., additional, Doiny, D., additional, Perez-Silva, A., additional, Castrejon Castrejon, S., additional, Estrada, A., additional, Ortega, M., additional, Lopez-Sendon, J. L., additional, Merino, J. L., additional, Garcia Fernandez, F. J., additional, Gallardo, R., additional, Pachon, M., additional, Almendral, J., additional, Martin, J., additional, Yahya, D., additional, Al-Mogheer, B., additional, Gouda, S., additional, Eweis, E., additional, El Ramly, M., additional, Abdelwahab, A., additional, Kassenberg, W., additional, Wittkampf, F. H. M., additional, Hof, I. E., additional, Heijden, J. H., additional, Neven, K. G. E. J., additional, Hauer, R. N. W., additional, Baratto, F., additional, Bignami, E., additional, Pappalardo, F., additional, Maccabelli, G., additional, Nicolotti, D., additional, Zangrillo, A., additional, Nagashima, M., additional, An, Y., additional, Okreglicki, A., additional, Russouw, C., additional, Tilz, R., additional, Yoshiga, Y., additional, Mathew, S., additional, Fuernkranz, A., additional, Rillig, A., additional, Wissner, E., additional, Ouyang, F., additional, De Sisti, A., additional, Tonet, J., additional, Gueffaf, F., additional, Touil, F., additional, Aouate, P., additional, Hidden-Lucet, F., additional, Makimoto, H., additional, Satomi, K., additional, Yamada, Y., additional, Okamura, H., additional, Noda, T., additional, Shimizu, W., additional, Aihara, N., additional, Kamakura, S., additional, Perez Silva, A., additional, Castrejon, S., additional, Gonzalez Vasserot, M., additional, Senges, J., additional, Brachmann, J., additional, Andresen, D., additional, Hoffmann, E., additional, Schumacher, B., additional, Willems, S., additional, Springer, B., additional, Kolb, C., additional, Akca, F., additional, Bauernfeind, T., additional, De Groot, N. M. S., additional, Schwagten, B., additional, Witsenburg, M., additional, Jordaens, L., additional, Szili-Torok, T., additional, Hata, Y., additional, Nakagami, R., additional, Watanabe, T., additional, Sato, A., additional, Watanabe, H., additional, Kabutoya, T., additional, Mituhashi, T., additional, Theuns, D. A. M. J., additional, Smith, T., additional, Pedersen, S. S., additional, Dabiri-Abkenari, L., additional, Prull, M. W., additional, Unverricht, S., additional, Bittlinsky, A., additional, Wirdemann, H., additional, Sasko, B., additional, Wirdeier, S., additional, Trappe, H. J., additional, Zorio Grima, E., additional, Rueda, J., additional, Medina, P., additional, Jaijo, T., additional, Sevilla, T., additional, Arnau, M. A., additional, Salvador, A., additional, Starrenburg, A. H., additional, Kraaier, K., additional, Scholten, M. F., additional, Van Der Palen, J., additional, De Haan, S., additional, Commandeur, J., additional, De Boer, K., additional, Beek, A. M., additional, Van Rossum, A. C., additional, Allaart, C. P., additional, Berne, P., additional, Porres, J. M., additional, Arnaiz, J. A., additional, Brugada, R., additional, Man, S., additional, Maan, A. C., additional, Thijssen, J., additional, Van Der Wall, E. E., additional, Schalij, M. J., additional, Burattini, L., additional, Burattini, R., additional, Swenne, C. A., additional, Bonny, A., additional, Ditah, I., additional, Larrazet, F., additional, Frank, R., additional, Fontaine, G., additional, Van Der Voort, P. H., additional, Alings, M., additional, Shimane, A., additional, Okajima, K., additional, Kanda, G., additional, Yokoi, K., additional, Yamada, S., additional, Taniguchi, Y., additional, Hayashi, T., additional, Kajiya, T., additional, Santos, M. C., additional, Wright, J., additional, Betts, J., additional, Denman, R., additional, Dominguez-Perez, L., additional, Arias Palomares, M. A., additional, Toquero, J., additional, Diaz-Infante, E., additional, Tercedor, L., additional, Valverde, I., additional, Napp, A., additional, Joosten, S., additional, Stunder, D., additional, Zink, M., additional, Marx, N., additional, Schauerte, P., additional, Silny, J., additional, Trucco, M. E., additional, Arce, M., additional, Palazzolo, J., additional, Femenia, F., additional, Glad, J. M., additional, Szymkiewicz, S. J., additional, Fernandez-Armenta, J., additional, Camara, O., additional, Mont, L. L., additional, Diaz, E., additional, Silva, E., additional, Frangi, A., additional, Brembilla-Perrot, B., additional, Laporte, F., additional, Morinigo, J., additional, Ledesma, C., additional, Hadid, C., additional, Ortiz, M., additional, Wolpert, C., additional, Cobo, E., additional, Navarro, X., additional, Arribas, F., additional, Miki, Y., additional, Naitoh, S., additional, Kumagai, K., additional, Goto, K., additional, Kaseno, K., additional, Oshima, S., additional, Taniguchi, K., additional, Rivera, S., additional, Albina, G., additional, Klein, A., additional, Laino, R., additional, Sammartino, V., additional, Giniger, A., additional, Muggenthaler, M., additional, Raju, H., additional, Papadakis, M., additional, Chandra, N., additional, Bastiaenen, R., additional, Behr, E. R., additional, Sharma, S., additional, Samniah, N., additional, Radezishvsky, Y., additional, Omari, H., additional, Rosenschein, U., additional, Perez Riera, A. R., additional, Ferreira, M., additional, Hopman, W. M., additional, Mcintyre, W. F., additional, Baranchuk, A. R., additional, Wongcharoen, W., additional, Keanprasit, K., additional, Phrommintikul, A., additional, Chaiwarith, R., additional, Yagishita, A., additional, Hachiya, H., additional, Nakamura, T., additional, Tanaka, Y., additional, Higuchi, K., additional, Kawabata, M., additional, Hirao, K., additional, Isobe, M., additional, Stoickov, V., additional, Ilic, S., additional, Deljanin Ilic, M., additional, Aagaard, P., additional, Sahlen, A., additional, Bergfeldt, L., additional, Braunschweig, F., additional, Sousa, A., additional, Lebreiro, A., additional, Sousa, C., additional, Oliveira, S., additional, Correia, A. S., additional, Rangel, I., additional, Freitas, J., additional, Maciel, M. J., additional, Asensio Lafuente, E., additional, Aguilera, A. A. C., additional, Corral, M. A. C. C., additional, Mendoza, K. L. M. C., additional, Nava, P. E. N. D., additional, Rendon, A. L. R. C., additional, Villegas, L. V. C., additional, Castillo, L. C. M., additional, Schaerf, R., additional, Develle, R., additional, Oliver, C., additional, Zinzius, P. Y., additional, Providencia, R. A., additional, Botelho, A., additional, Trigo, J., additional, Nascimento, J., additional, Quintal, N., additional, Mota, P., additional, Leitao-Marques, A. M., additional, Borbola, J., additional, Abraham, P., additional, Foldesi, C. S., additional, Kardos, A., additional, Almeida, S., additional, Santos, M. B., additional, Quaresma, R., additional, Morgado, F. B., additional, Adragao, P., additional, Fatemi, M., additional, Didier, R., additional, Le Gal, G., additional, Etienne, Y., additional, Jobic, Y., additional, Gilard, M., additional, Boschat, J., additional, Mansourati, J., additional, Zubaid, M., additional, Rashed, W., additional, Alsheikh-Ali, A., additional, Almahmeed, W., additional, Shehab, A., additional, Sulaiman, K., additional, Asaad, N., additional, Amin, H., additional, Boersma, L. V. A., additional, Swaans, M., additional, Post, M., additional, Rensing, B., additional, Jarverud, K., additional, Broome, M., additional, Noren, K., additional, Svensson, T., additional, Hjelm, S., additional, Hollmark, M., additional, Bjorling, A., additional, Maeda, K., additional, Takagi, M., additional, Suzuki, K., additional, Tatsumi, H., additional, Yoshiyama, M., additional, Simeonidou, E., additional, Michalakeas, C., additional, Kastellanos, S., additional, Varounis, C., additional, Nikolopoulou, A., additional, Koniari, C., additional, Anastasiou-Nana, M., additional, Furukawa, T., additional, Maggi, R., additional, Bertolone, C., additional, Fontana, D., additional, Brignole, M., additional, Pietrucha, A. Z., additional, Wnuk, M., additional, Bzukala, I., additional, Mroczek-Czernecka, D., additional, Konduracka, E., additional, Kruszelnicka, O., additional, Piwowarska, W., additional, Nessler, J., additional, Edvardsson, N., additional, Rieger, G., additional, Garutti, C., additional, Linker, N., additional, Jorge, C., additional, Silva Marques, J., additional, Veiga, A., additional, Cruz, J., additional, Correia, M. J., additional, Sousa, J., additional, Miltenberger-Miltenyi, G., additional, Nunes Diogo, A., additional, Matic, D., additional, Mrdovic, I., additional, Stankovic, G., additional, Asanin, M., additional, Antonijevic, N., additional, Matic, M., additional, Kocev, N., additional, Vasiljevic, Z., additional, Ramirez-Marrero, M. A., additional, Perez-Villardon, B., additional, Delgado-Prieto, J. L., additional, Jimenez-Navarro, M., additional, De Teresa-Galvan, E., additional, De Mora-Martin, M., additional, Sztefko, K., additional, Malek, A., additional, De Groot, N., additional, Shalganov, T., additional, Schalij, M., additional, Rivas, N., additional, Casaldaliga, J., additional, Roca, I., additional, Pijuan, A., additional, Perez-Rodon, J., additional, Dos, L., additional, Garcia-Dorado, D., additional, Moya, A., additional, Baruteau, A.- E., additional, Behaghel, A., additional, Chatel, S., additional, Schott, J. J., additional, Daubert, J. C., additional, Le Marec, H., additional, Probst, V., additional, Navarro-Manchon, J., additional, Molina, P., additional, Igual, B., additional, Bermejo, M., additional, Giner, J., additional, Bourgonje, V. J. A., additional, Vos, M. A., additional, Ozdemir, S., additional, Doisne, N., additional, Van Der Heyden, M. A. G., additional, Van Veen, A. A. B., additional, Sipido, K., additional, Antoons, G., additional, Altieri, P. I., additional, Escobales, N., additional, Crespo, M., additional, Banchs, H. L., additional, Sciarra, L., additional, Bloise, R., additional, Allocca, G., additional, Marras, E., additional, Lioy, E., additional, Delise, P., additional, Priori, S., additional, and Calo', L., additional

Published
2011
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34. Hot topics: arrhythmias

Author

Chik, W. W. B., primary, Robinson, D., additional, Malchano, Z., additional, Allison, J., additional, Saadat, V., additional, Kovoor, P., additional, Thomas, S. P., additional, Thiagalingam, A., additional, Bulava, A., additional, Hanis, J., additional, Osmera, O., additional, Rehouskova, K., additional, Sitek, D., additional, Novotny, A., additional, Aldhoon, B., additional, Wichterle, D., additional, Peichl, P., additional, Cihak, R., additional, Kautzner, J., additional, Le Heuzey, J.- Y., additional, Breithardt, G., additional, Camm, A. J., additional, Crijns, H. J., additional, Dorian, P., additional, Kowey, P. R., additional, Naditch-Brule, L., additional, Prystowsky, E. N., additional, Baruteau, A.- E., additional, Behaghel, A., additional, Chatel, S., additional, Mabo, P., additional, Schott, J. J., additional, Daubert, J. C., additional, Le Marec, H., additional, Probst, V., additional, Regoli, F., additional, Nucifora, G., additional, Faletra, F., additional, Pasotti, E., additional, Pedrazzini, G., additional, Moccetti, T., additional, Auricchio, A., additional, Szili-Torok, T., additional, Ujvari, B., additional, Bauernfeind, T., additional, Domburg, R. T., additional, Balk, A., additional, Jordaens, L., additional, Simoons, M., additional, Caliskan, K., additional, Uldry, L., additional, Van Zaen, J., additional, Kappenberger, L., additional, Vesin, J. M., additional, Ferreira Santos, L., additional, Pereira, T., additional, Rodrigues, B., additional, Machado, J., additional, Castedo, S., additional, Henriques, C., additional, Matos, A., additional, Oliveira Santos, J., additional, and Buttu, A., additional

Published
2011
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36. Endomyocardial biopsies: a new approach for studying the electrical and mechanical properties of human ventricular myocardium

Author

E. Drouin, Charpentier F, Chevallier Jc, Laurent K, C. Gauthier, and Le Marec H

Subjects
medicine.medical_specialty, Pathology, business.industry, Biopsy, Heart Ventricles, Isoproterenol, Action Potentials, Myocardial Contraction, Endomyocardial biopsy, Ventricular myocardium, Internal medicine, Calcium concentration, medicine, Cardiology, Ventricular Function, Right, Humans, Cardiology and Cardiovascular Medicine, business, Molecular Biology, Endocardium
Abstract

The novel endomyocardial biopsy approach described here could facilitate the study of some human pathologies for which specimens are currently unavailable. Electrical and mechanical characteristics such as rate responses, effect of extracellular calcium concentration changes and β-adrenergic tone were similar to those determined for other human ventricular tissues, indicating that endomyocardial biopsies are suitable for physiological studies. This new source of cardiac tissues should facilitate the investigation of cellular mechanisms involved in the development of previously inaccessible human diseases.

Published
1994

37. Moderated Posters session II: Basic Pathophysiology / Basic Science * Thursday 9 December 2010, 15:30-16:30

Author

Marchal, P., primary, Lairez, O., additional, Galinier, M., additional, Roncalli, J., additional, Elbaz, M., additional, Rousseau, H., additional, Chabbert, V., additional, Barrier, P., additional, Marachet, M. A., additional, Carrie, D., additional, Coisne, D., additional, Guerin, C., additional, Lugiez, M., additional, Guivier, C., additional, Tane, D., additional, Menard, M., additional, Christiaens, L., additional, Sahlen, A., additional, Shahgaldi, K., additional, Norman, M., additional, Manouras, A., additional, Winter, R., additional, Brodin, L., additional, Rajamannan, N., additional, Snoer, M., additional, Monk-Hansen, T., additional, Dela, F., additional, Prescott, E., additional, Rudenick, P. A., additional, Bordone, M., additional, Bijnens, B., additional, Soudah, E., additional, Onate, E., additional, Garcia-Dorado, D., additional, Evangelista, A., additional, Drapkina, O., additional, Ivashkin, V., additional, Ashikhmin, Y., additional, Camarozano, A. C., additional, Cyrino, F., additional, Camarozano, K., additional, Botino, D., additional, Bouskela, E., additional, Hestenes, S., additional, Skulstad, H., additional, Halvorsen, P. S., additional, Hyler, S., additional, Bugge, J. F., additional, Fosse, E., additional, Nielsen, E. W., additional, Edvardsen, T., additional, Martin Garcia, A., additional, Le Tourneau, T., additional, Le Marec, H., additional, Probst, V., additional, Schott, J. J., additional, Kyndt, F., additional, Slaugenhaupt, S., additional, Solis Martin, J., additional, Martin-Luengo, C., additional, and Levine, R., additional

Published
2010
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39. Long-Term Prognosis of Patients Diagnosed With Brugada Syndrome

Author

Probst, V., primary, Veltmann, C., additional, Eckardt, L., additional, Meregalli, P.G., additional, Gaita, F., additional, Tan, H.L., additional, Babuty, D., additional, Sacher, F., additional, Giustetto, C., additional, Schulze-Bahr, E., additional, Borggrefe, M., additional, Haissaguerre, M., additional, Mabo, P., additional, Le Marec, H., additional, Wolpert, C., additional, and Wilde, A.A.M., additional

Published
2010
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40. Polymorphisms associated with ventricular tachyarrhythmias: rationale, design, and endpoints of the 'diagnostic data influence on disease management and relation of genomics to ventricular tachyarrhythmias in implantable cardioverter/defibrillator patients (DISCOVERY)' study

Author

Wieneke, H., primary, Spencker, S., additional, Svendsen, J. H., additional, Martinez, J. G., additional, Strohmer, B., additional, Toivonen, L., additional, Le Marec, H., additional, Garcia, J., additional, Kaup, B., additional, Soykan, O., additional, Corrado, D., additional, and Siffert, W., additional

Published
2010
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43. G024 Implication des canaux KATP dans le syndrome de repolarisation précoce

Author

Chatel, S., primary, Haissaguerre, M., additional, Sacher, F., additional, Weerasooriya, R., additional, Probst, V., additional, Loussouarn, G., additional, Horlitz, M., additional, Liersch, R., additional, Schulze-Bahr, E., additional, Wilde, A., additional, Kääb, S., additional, Le Marec, H., additional, and Schott, J.-J., additional

Published
2009
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44. G023 SCN5A mutations and the role of genetic background in the pathophysiology of brugada syndrome

Author

Barc, J., primary, Probst, V., additional, Wilde, A.A.M., additional, Sacher, F., additional, Babuty, D., additional, Mabo, P., additional, Mansourati, J., additional, Le Scouarnec, S., additional, Kyndt, F., additional, Guicheney, P., additional, Albuisson, J., additional, Meregalli, P.-G., additional, Le Marec, H., additional, Tan, H.-L., additional, and Schott, J.-J., additional

Published
2009
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