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202 results on '"Le Gal, S."'

1. P229 Do CFTR modulators interfere with microbiological diagnosis?

Author

Héry-Arnaud, G., primary, Vallet, S., additional, Bougnoux, M.-E., additional, Cardot-Martin, E., additional, Cassaing, S., additional, Chesnay, A., additional, Crémet, L., additional, Doléans-Jordheim, A., additional, Dupont, C., additional, Ferroni, A., additional, Gangneux, J.-P., additional, Garnier, F., additional, Guet-Revillet, H., additional, Guillard, T., additional, Handala, L., additional, Herrmann, J.-L., additional, Jeannot, K., additional, Lachaud, L., additional, Le Gal, S., additional, Lehours, P., additional, Mainardi, J.-L., additional, Millon, L., additional, Piau, C., additional, Persat, F., additional, Villena, I., additional, Yéra, H., additional, Velo-Suarez, L., additional, and Delhaes, L., additional

Published
2024
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2. Antifungal susceptibility testing practices in mycology laboratories in France, 2018

Author

Bellanger, A.-P., Persat, F., Foulet, F., Bonnal, C., Accoceberry, I., Angebault, C., Angoulvant, A., Augereau, O., Bailly, E., Bert, F., Bonhomme, J., Bouchara, J.-P., Bougnoux, M.-E., Bourdeau, P., Bouteille, B., Brun, S., Brunet, K., Camin-Ravenne, A.-M., Cassaing, S., Chouaki, T., Cornet, M., Costa, D., Desbois, N., Dorin, J., Fekkar, A., Fiacre, A., Fréalle, E., Gangneux, J.-P., Guillot, J., Guitard, J., Hasseine, L., Huguenin, A., Lachaud, L., Larréché, S., Lavergne, R.-A., Le Gal, S., Le Govic, Y., Letscher-Bru, V., Machouart, M., Mazars, E., Nourrisson, C., Paugam, A., Ranque, S., Risco-Castillo, V., Sasso, M., Sautour, M., Sendid, B., Senghor, Y., Botterel, F., and Dannaoui, Eric

Published
2020
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17. Developing collaborative works for faster progress on fungal respiratory infections in cystic fibrosis

Author

Schwarz C, Vandeputte P, Rougeron A, Giraud S, Dugé de Bernonville T, Duvaux L, Gastebois A, Alastruey-Izquierdo A, Martín-Gomez MT, Mazuelos EM, Sole A, Cano J, Pemán J, Quindos G, Botterel F, Bougnoux ME, Chen S, Delhaès L, Favennec L, Ranque S, Sedlacek L, Steinmann J, Vazquez J, Williams C, Meyer W, Le Gal S, Nevez G, Fleury M, Papon N, Symoens F, Bouchara JP, and ECMM/ISHAM working group Fungal respiratory infections in Cystic

Subjects
cystic fibrosis, fungal respiratory infections, biological diagnosis, treatment, Scedosporium species, pathogenic mechanisms
Abstract

Cystic fibrosis (CF) is the major genetic inherited disease in Caucasian populations. The respiratory tract of CF patients displays a sticky viscous mucus, which allows for the entrapment of airborne bacteria and fungal spores and provides a suitable environment for growth of microorganisms, including numerous yeast and filamentous fungal species. As a consequence, respiratory infections are the major cause of morbidity and mortality in this clinical context. Although bacteria remain the most common agents of these infections, fungal respiratory infections have emerged as an important cause of disease. Therefore, the International Society for Human and Animal Mycology (ISHAM) has launched a working group on Fungal respiratory infections in Cystic Fibrosis (Fri-CF) in October 2006, which was subsequently approved by the European Confederation of Medical Mycology (ECMM). Meetings of this working group, comprising both clinicians and mycologists involved in the follow-up of CF patients, as well as basic scientists interested in the fungal species involved, provided the opportunity to initiate collaborative works aimed to improve our knowledge on these infections to assist clinicians in patient management. The current review highlights the outcomes of some of these collaborative works in clinical surveillance, pathogenesis and treatment, giving special emphasis to standardization of culture procedures, improvement of species identification methods including the development of nonculture-based diagnostic methods, microbiome studies and identification of new biological markers, and the description of genotyping studies aiming to differentiate transient carriage and chronic colonization of the airways. The review also reports on the breakthrough in sequencing the genomes of the main Scedosporium species as basis for a better understanding of the pathogenic mechanisms of these fungi, and discusses treatment options of infections caused by multidrug resistant microorganisms, such as Scedosporium and Lomentospora species and members of the Rasamsonia argillacea species complex.

Published
2018

22. 159 Pneumocystis jirovecii and cystic fibrosis in Britanny, France

Author

Le Gal, S., primary, Robert-Gangneux, F., additional, Damiani, C., additional, Virmaux, M., additional, Belleguic, C., additional, Deneuville, E., additional, Rault, G., additional, Ramel, S., additional, Bihan, J.L., additional, Guillaud-Saumur, T., additional, Pougnet, L., additional, Totet, A., additional, Gangneux, J.-P., additional, Bouchara, J.-P., additional, and Nevez, G., additional

Published
2017
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25. Ecology of Scedosporium Species: Present Knowledge and Future Research.

Author

Rougeron, A., Giraud, S., Alastruey-Izquierdo, A., Cano-Lira, J., Rainer, J., Mouhajir, A., Le Gal, S., Nevez, G., Meyer, W., and Bouchara, J. P.

Abstract

The genus Scedosporium, which comprises at least five clinically relevant species, i.e. Scedosporium apiospermum, Scedosporium boydii, Scedosporium aurantiacum, Scedosporium dehoogii and Scedosporium minutisporum, ranks the second among the filamentous fungi colonizing the airways of patients with cystic fibrosis (CF). This colonization of the airways is thought to contribute to the inflammatory reaction leading to a progressive deterioration of the lung function. Additionally, these colonizing fungi may lead to severe disseminated infections in case of lung transplantation. Therefore, considering the low susceptibility of Scedosporium species to all current antifungal drugs, preventive measures should be defined to reduce the risk of exposure to these fungi for non-colonized CF patients. With this in mind, several studies have been conducted to elucidate the ecology of these fungi and to define possible sources of patient contamination. This review will summarize the major outcomes of those studies, including: the clear demonstration that ecological niches of Scedosporium species are strongly impacted by human activities, and the ability of Scedosporium species to degrade aliphatic and aromatic pollutants which supports the high occurrence of these species in contaminated soils and polluted waters and makes them promising candidates for bioremediation purposes. Finally, prospects for future research in this field are proposed. [ABSTRACT FROM AUTHOR]

Published
2018
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27. Déterminants de virulence et d'adaptation des virus influenza : une délétion dans la tige de la neuraminidase constitue un facteur de virulence chez les volailles domestiques

Author

Marc, Daniel, Aline, Fleur, Larcher, Thibaut, Munier, S, Soubieux, Denis, Guigand, Lydie, Le Gal, S, van der Werf, S, Quéré, Pascale, Cherel, Y, Naffakh, N, Infectiologie Animale et Santé Publique (UR IASP), Institut National de la Recherche Agronomique (INRA), Développement et Pathologie du Tissu Musculaire (DPTM), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Nantes, and Institut Pasteur [Paris]

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2009

28. Une délétion dans la tige de la neuraminidase d'un virus grippal issu de l'avifaune sauvage constitue un facteur de virulence chez des volailles domestiques

Author

Munier, S, Larcher, Thibaut, Aline, Fleur, Soubieux, Denis, Su, B, Le Gal, S, van der Werf, S, Labrosse, B, Quéré, Pascale, Cherel, Yan, Marc, Daniel, Naffakh, N, Institut Pasteur [Paris], Développement et Pathologie du Tissu Musculaire (DPTM), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Nantes, Infectiologie Animale et Santé Publique (UR IASP), Institut National de la Recherche Agronomique (INRA), and Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

National audience

Published
2009

29. Evaluation of the risk of fungal colonization/infection in patients with cystic fibrosis: An international prospective study comparing the performance of media for mycological culturing MucoFong International Project (MFIP)

Author

Touati, K., primary, Faure, C.O., additional, Cornet, M., additional, Botterel, F., additional, Dannaoui, E., additional, Morio, F., additional, Lepape, P., additional, Grenouillet, F., additional, Favennec, L., additional, Le Gal, S., additional, Nevez, G., additional, Borman, A., additional, Saegeman, V., additional, Lagrou, K., additional, Gomez, E., additional, Caro-Luis, M., additional, Canton, R., additional, Campana, S., additional, Buzina, W., additional, Chen, S., additional, Meyer, W., additional, Roilides, E., additional, Simitsopoulou, M., additional, Manso, E., additional, Cariani, L., additional, Biffi, A., additional, Fiscarelli, E., additional, Riccioti, G., additional, Sendid, B., additional, Pihet, M., additional, Bouchara, J.-P., additional, and Delhaes, L., additional

Published
2014
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30. Complications Associated With Photoselective Vaporization of the Prostate: Categorization by a Panel of GreenLight Users According to Clavien Score and Report of a Single-center Experience

Author

Peyronnet, Benoit, primary, Pradere, Benjamin, additional, Brichart, Nicolas, additional, Bodin, Thomas, additional, Bertrand, Philippe, additional, Bruyère, Franck, additional, Atassi, A., additional, Benmeziani, R., additional, Bodin, T., additional, Breque, M., additional, Brichart, N., additional, Bron, J., additional, Bruyere, F., additional, Cloche, P., additional, Corbel, L., additional, Cormier, L., additional, Cuvelier, G., additional, Delporte, G., additional, Fennouri, M., additional, Ferhi, K., additional, Fournier, G., additional, Gabbay, G., additional, Hurtes, X., additional, Laplace, B., additional, Le Gal, S., additional, Lecouteux, A., additional, Lesur, G., additional, Lokmane, M., additional, Mathieu, R., additional, Metois, P., additional, Miaadi, N., additional, Misrai, V., additional, Moreau, J.L., additional, Mouly, P., additional, Muyshondt, C., additional, Obringer, L., additional, Perrouin-Verbe, M.A., additional, Peyronnet, B., additional, Pradere, B., additional, Prezelin, Y., additional, Rigaud, P., additional, Salin, A., additional, Tabchouri, N., additional, Tanchoux, C., additional, Theveniaud, P., additional, Thoulouzan, M., additional, Thuillier, C., additional, and Verhoest, G., additional

Published
2014
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32. Diversité de Pneumocystis jirovecii en Guyane

Author

Le Gal, S., primary, Blanchet, D., additional, Damiani, C., additional, Merle, C., additional, Virmaux, M., additional, Guillot, G., additional, Abboud, P., additional, Totet, A., additional, Carme, B., additional, and Nevez, G., additional

Published
2014
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33. À propos de 544 cas de pneumocystose pulmonaire : presentation clinique et pronostic

Author

Roux, A., primary, Canet, E., additional, Valade, S., additional, Gangneux-Robert, F., additional, Sarfati, C., additional, Lafabrie, A., additional, Maubon, D., additional, Debourgogne, A., additional, Le Gal, S., additional, Dalle, F., additional, Leterrier, M., additional, Toubas, D., additional, Pomares, C., additional, Bellanger, A.P., additional, Bonhomme, J., additional, Magne, D., additional, Pons, D., additional, Hennequin, C., additional, Maury, E., additional, Roux, P., additional, and Azoulay, É., additional

Published
2014
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34. Étude fongipic « Évaluation de l’exposition aux moisissures domestiques des sujets allergiques en picardie »

Author

Le Gal, S., primary, Damiani, C., additional, Sauvage, A., additional, Taillaint, S., additional, Ramon, C., additional, Benabes, B., additional, Davigny, O., additional, Lepilliez, A., additional, Monsigny, M., additional, Pautard, J.-C., additional, Popin, E., additional, Quequet, C., additional, Tardieux, P., additional, Tuloup, E., additional, Adjide, C., additional, Bayat, S., additional, Nevez, G., additional, and Totet, A., additional

Published
2014
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49. A Cluster of Pneumocystis Infections Among Renal Transplant Recipients: Molecular Evidence of Colonized Patients as Potential Infectious Sources of Pneumocystis jirovecii

Author

Le Gal, S., primary, Damiani, C., additional, Rouille, A., additional, Grall, A., additional, Treguer, L., additional, Virmaux, M., additional, Moalic, E., additional, Quinio, D., additional, Moal, M.-C., additional, Berthou, C., additional, Saliou, P., additional, Le Meur, Y., additional, Totet, A., additional, and Nevez, G., additional

Published
2012
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