739 results on '"Le Bars, D"'
Search Results
2. Fisiología del dolor: aspectos psicofisiológicos y mecanismos periféricos
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Le Bars, D., Mouraux, A., and Plaghki, L.
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- 2018
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3. Fisiologia del dolore
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Plaghki, L., Mouraux, A., and Le Bars, D.
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- 2018
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4. Bases neurophysiologiques de la douleur
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Plaghki, L., primary and Le Bars, D., additional
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- 2019
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5. Global Projections of Storm Surges Using High-Resolution CMIP6 Climate Models
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Muis, S. Aerts, J. C. J. H. Á. Antolínez, J. A. Dullaart, J. C. Duong, T. M. Erikson, L. Haarsma, R. J. Apecechea, M. I. Mengel, M. Le Bars, D. O’Neill, A. Ranasinghe, R. Roberts, M. J. Verlaan, M. Ward, P. J. Yan, K. and Muis, S. Aerts, J. C. J. H. Á. Antolínez, J. A. Dullaart, J. C. Duong, T. M. Erikson, L. Haarsma, R. J. Apecechea, M. I. Mengel, M. Le Bars, D. O’Neill, A. Ranasinghe, R. Roberts, M. J. Verlaan, M. Ward, P. J. Yan, K.
- Abstract
In the coming decades, coastal flooding will become more frequent due to sea-level rise and potential changes in storms. To produce global storm surge projections from 1950 to 2050, we force the Global Tide and Surge Model with a ∼25-km resolution climate model ensemble from the Coupled Model Intercomparison Project Phase 6 High Resolution Model Intercomparison Project (HighResMIP). This is the first time that such a high-resolution ensemble is used to assess changes in future storm surges across the globe. We validate the present epoch (1985–2014) against the ERA5 climate reanalysis, which shows a good overall agreement. However, there is a clear spatial bias with generally a positive bias in coastal areas along semi-enclosed seas and negative bias in equatorial regions. Comparing the future epoch (2021–2050) against the historical epoch (1951–1980), we project ensemble-median changes up to 0.1 (or 20%) in the 1 in 10-year storm surge levels. These changes are not uniform across the globe with decreases along the coast of Mediterranean and northern Africa and southern Australia and increases along the south coast of Australia and Alaska. There are also increases along (parts) of the coasts of northern Caribbean, eastern Africa, China and the Korean peninsula, but with less agreement among the HighResMIP ensemble. Information resulting from this study can be used to inform broad-scale assessment of coastal impacts under future climate change.
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- 2023
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6. The impacts of coastal flooding and sea level rise on critical infrastructure: a novel storyline approach
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Koks, Elco E., primary, Le Bars, D., additional, Essenfelder, A.H, additional, Nirandjan, S., additional, and Sayers, P., additional
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- 2022
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7. Douleur et thermorégulation. La région bulbaire rostroventrale
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El Bitar, N. and Le Bars, D.
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- 2016
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8. Douleur et thermorégulation. La thermorégulation chez l’animal
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El Bitar, N., Le Bars, D., and Neurosciences Paris-Seine
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- 2015
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9. The impacts of coastal flooding and sea level rise on critical infrastructure: a novel storyline approach.
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Koks, Elco E., Le Bars, D., Essenfelder, A.H, Nirandjan, S., and Sayers, P.
- Subjects
INFRASTRUCTURE (Economics) ,SEA level ,STORM surges ,STORMS ,FLOOD risk ,FLOODS ,COMMUNITIES - Abstract
This study presents an event-based storyline framework to assess the influence of future climatic and socioeconomic conditions on coastal flood impacts to critical infrastructure. The framework combines well-established quantitative methods of sea level rise, coastal inundation, and critical infrastructure (CI) physical damage assessments into an integrated modelling approach. We apply our approach to re-imagine three historic events: storm Xaver, storm Xynthia , and a storm surge event along the coast of Emilia Romagna (Italy). Our results indicate that northern Germany would benefit mostly from coordinated adaptation action to reduce the flood impact, whereas the southwestern coast of France would find the highest damage reduction through asset-level 'autonomous' adaptation action. Our approach helps to improve the scientific understanding of how coastal flood risk are assessed and best managed, and forces a distillation of the science into an accessible narrative to support policymakers and asset owners to make progress towards more climate-resilient coastal communities. [ABSTRACT FROM AUTHOR]
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- 2023
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10. ESICM LIVES 2016: part one: Milan, Italy. 1-5 October 2016
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Bos, L., Schouten, L., van Vught, L., Wiewel, M., Ong, D., Cremer, O., Artigas, A., Martin-Loeches, I., Hoogendijk, A., van der Poll, T., Horn, J., Juffermans, N., Schultz, M., de Prost, N., Pham, T., Carteaux, G., Dessap, A. Mekontso, Brun-Buisson, C., Fan, E., Bellani, G., Laffey, J., Mercat, A., Brochard, L., Maitre, B., Howells, P. A., Thickett, D. R., Knox, C., Park, D. P., Gao, F., Tucker, O., Whitehouse, T., McAuley, D. F., Perkins, G. D., Pham, T., Laffey, J., Bellani, G., Fan, E., Pisani, L., Roozeman, J. P., Simonis, F. D., Giangregorio, A., Schouten, L. R., Van der Hoeven, S. M., Horn, J., Neto, A. Serpa, Festic, E., Dondorp, A. M., Grasso, S., Bos, L. D., Schultz, M. J., Koster-Brouwer, M., Verboom, D., Scicluna, B., van de Groep, K., Frencken, J., Schultz, M., van der Poll, T., Bonten, M., Cremer, O., Ko, J. I., Kim, K. S., Suh, G. J., Kwon, W. Y., Kim, K., Shin, J. H., Ranzani, O. T., Prina, E., Menendez, R., Ceccato, A., Mendez, R., Cilloniz, C., Gabarrus, A., Ferrer, M., Torres, A., Urbano, A., Zhang, L. A., Swigon, D., Pike, F., Parker, R. S., Clermont, G., Scheer, C., Kuhn, S. O., Modler, A., Vollmer, M., Fuchs, C., Hahnenkamp, K., Rehberg, S., Gründling, M., Taggu, A., Darang, N., Öveges, N., László, I., Tánczos, K., Németh, M., Lebák, G., Tudor, B., Érces, D., Kaszaki, J., Huber, W., Trásy, D., Molnár, Z., Ferrara, G., Edul, V. S. Kanoore, Canales, H. S., Martins, E., Canullán, C., Murias, G., Pozo, M. O., Eguillor, J. F. Caminos, Buscetti, M. G., Ince, C., Dubin, A., Aya, H. D., Rhodes, A., Fletcher, N., Grounds, R. M., Cecconi, M., Jacquet-Lagrèze, M., Riche, M., Schweizer, R., Portran, P., Fornier, W., Lilot, M., Neidecker, J., Fellahi, J. L., Escoresca-Ortega, A., Gutiérrez-Pizarraya, A., Charris-Castro, L., Corcia-Palomo, Y., Fernandez-Delgado, E., Garnacho-Montero, J., Roger, C., Muller, L., Elotmani, L., Lipman, J., Lefrant, J. Y., Roberts, J. A., Muñoz-Bermúdez, R., Samper, M., Climent, C., Vasco, F., Sara, V., Luque, S., Campillo, N., Cerrato, S. Grau, Masclans, J. R., Alvarez-Lerma, F., Brugger, S. Carvalho, Jimenez, G. Jimenez, Torner, M. Miralbés, Cabello, J. Trujillano, Garrido, B. Balsera, Casals, X. Nuvials, Gaite, F. Barcenilla, Vidal, M. Vallverdú, Martínez, M. Palomar, Gusarov, V., Shilkin, D., Dementienko, M., Nesterova, E., Lashenkova, N., Kuzovlev, A., Zamyatin, M., Demoule, A., Carreira, S., Lavault, S., Palancca, O., Morawiec, E., Mayaux, J., Arnulf, I., Similowski, T., Rasmussen, B. S., Maltesen, R. G., Hanifa, M., Pedersen, S., Kristensen, S. R., Wimmer, R., Panigada, M., Bassi, G. Li, Ranzani, O. T., Kolobow, T., Zanella, A., Cressoni, M., Berra, L., Parrini, V., Kandil, H., Salati, G., Livigni, S., Amatu, A., Andreotti, A., Tagliaferri, F., Moise, G., Mercurio, G., Costa, A., Vezzani, A., Lindau, S., Babel, J., Cavana, M., Consonni, D., Pesenti, A., Gattinoni, L., Torres, A., Mansouri, P., Zand, F., Zahed, L., Dehghanrad, F., Bahrani, M., Ghorbani, M., Cambiaghi, B., Moerer, O., Mauri, T., Kunze-Szikszay, N., Ritter, C., Pesenti, A., Quintel, M., Vilander, L. M., Kaunisto, M. A., Vaara, S. T., Pettilä, V., Mulier, J. L. G. Haitsma, Rozemeijer, S., Spoelstra-de Man, A. M. E., Elbers, P. E., Tuinman, P. R., de Waard, M. C., Oudemans-van Straaten, H. M., Liberatore, A. M. A., Souza, R. B., Martins, A. M. C. R. P. F., Vieira, J. C. F., Koh, I. H. J., Martínez, M. Galindo, Sánchez, R. Jiménez, Gascón, L. Martínez, Mulero, M. D. Rodríguez, Freire, A. Ortín, Muñoz, A. Ojados, Acebes, S. Rebollo, Martínez, Á. Fernández, Aliaga, S. Moreno, Para, L. Herrera, Payá, J. Murcia, Mulero, F. Rodríguez, Guerci, P., Ince, Y., Heeman, P., Ergin, B., Ince, C., Uz, Z., Massey, M., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Toraman, F., Ince, C., Longbottom, E. R., Torrance, H. D., Owen, H. C., Hinds, C. J., Pearse, R. M., O’Dywer, M. J., Trogrlic, Z., van der Jagt, M., Lingsma, H., Ponssen, H. H., Schoonderbeek, J. F., Schreiner, F., Verbrugge, S. J., Duran, S., van Achterberg, T., Bakker, J., Gommers, D. A. M. P. J., Ista, E., Krajčová, A., Waldauf, P., Duška, F., Shah, A., Roy, N., McKechnie, S., Doree, C., Fisher, S., Stanworth, S. J., Jensen, J. F., Overgaard, D., Bestle, M. H., Christensen, D. F., Egerod, I., Pivkina, A., Gusarov, V., Zhivotneva, I., Pasko, N., Zamyatin, M., Jensen, J. F., Egerod, I., Bestle, M. H., Christensen, D. F., Alklit, A., Hansen, R. L., Knudsen, H., Grode, L. B., Overgaard, D., Hravnak, M., Chen, L., Dubrawski, A., Clermont, G., Pinsky, M. R., Parry, S. M., Knight, L. D., Connolly, B. C., Baldwin, C. E., Puthucheary, Z. A., Denehy, L., Hart, N., Morris, P. E., Mortimore, J., Granger, C. L., Jensen, H. I., Piers, R., Van den Bulcke, B., Malmgren, J., Metaxa, V., Reyners, A. K., Darmon, M., Rusinova, K., Talmor, D., Meert, A. P., Cancelliere, L., Zubek, L., Maia, P., Michalsen, A., Decruyenaere, J., Kompanje, E., Vanheule, S., Azoulay, E., Vansteelandt, S., Benoit, D., Van den Bulcke, B., Piers, R., Jensen, H. I., Malmgren, J., Metaxa, V., Reyners, A. K., Darmon, M., Rusinova, K., Talmor, D., Meert, A. P., Cancelliere, L., Zubek, L., Maia, P., Michalsen, A., Decruyenaere, J., Kompanje, E., Vanheule, S., Azoulay, E., Vansteelandt, S., Benoit, D., Ryan, C., Dawson, D., Ball, J., Noone, K., Aisling, B., Prudden, S., Ntantana, A., Matamis, D., Savvidou, S., Giannakou, M., Gouva, M., Nakos, G., Koulouras, V., Aron, J., Lumley, G., Milliken, D., Dhadwal, K., McGrath, B. A., Lynch, S. J., Bovento, B., Sharpe, G., Grainger, E., Pieri-Davies, S., Wallace, S., McGrath, B., Lynch, S. J., Bovento, B., Grainger, E., Pieri-Davies, S., Sharpe, G., Wallace, S., Jung, M., Cho, J., Park, H., Suh, G., Kousha, O., Paddle, J., Gripenberg, L. Gamrin, Rehal, M. Sundström, Wernerman, J., Rooyackers, O., de Grooth, H. J., Choo, W. P., Spoelstra-de Man, A. M., Swart, E. L., Oudemans-van Straaten, H. M., Talan, L., Güven, G., Altıntas, N. D., Padar, M., Uusvel, G., Starkopf, L., Starkopf, J., Blaser, A. Reintam, Kalaiselvan, M. S., Arunkumar, A. S., Renuka, M. K., Shivkumar, R. L., Volbeda, M., ten Kate, D., Hoekstra, M., van der Maaten, J. M., Nijsten, M. W., Komaromi, A., Rooyackers, O., Wernerman, J., Norberg, Å., Smedberg, M., Mori, M., Pettersson, L., Norberg, Å., Rooyackers, O., Wernerman, J., Theodorakopoulou, M., Christodoulopoulou, T., Diamantakis, A., Frantzeskaki, F., Kontogiorgi, M., Chrysanthopoulou, E., Lygnos, M., Diakaki, C., Armaganidis, A., Gundogan, K., Dogan, E., Coskun, R., Muhtaroglu, S., Sungur, M., Ziegler, T., Guven, M., Kleyman, A., Khaliq, W., Andreas, D., Singer, M., Meierhans, R., Schuepbach, R., De Brito-Ashurst, I., Zand, F., Sabetian, G., Nikandish, R., Hagar, F., Masjedi, M., Maghsudi, B., Vazin, A., Ghorbani, M., Asadpour, E., Kao, K. C., Chiu, L. C., Hung, C. Y., Chang, C. H., Li, S. H., Hu, H. C., El Maraghi, S., Ali, M., Rageb, D., Helmy, M., Marin-Corral, J., Vilà, C., Masclans, J. R., Vàzquez, A., Martín-Loeches, I., Díaz, E., Yébenes, J. C., Rodriguez, A., Álvarez-Lerma, F., Varga, N., Cortina-Gutiérrez, A., Dono, L., Martínez-Martínez, M., Maldonado, C., Papiol, E., Pérez-Carrasco, M., Ferrer, R., Nweze, K., Morton, B., Welters, I., Houard, M., Voisin, B., Ledoux, G., Six, S., Jaillette, E., Nseir, S., Romdhani, S., Bouneb, R., Loghmari, D., Aicha, N. Ben, Ayachi, J., Meddeb, K., Chouchène, I., Khedher, A., Boussarsar, M., Chan, K. S., Yu, W. L., Marin-Corral, J., Vilà, C., Masclans, J. R., Nolla, J., Vidaur, L., Bonastre, J., Suberbiola, B., Guerrero, J. E., Rodriguez, A., Coll, N. Ramon, Jiménez, G. Jiménez, Brugger, S. Carvalho, Calero, J. Codina, Garrido, B. Balsera, García, M., Martínez, M. Palomar, Vidal, M. Vallverdú, de la Torre, M. C., Vendrell, E., Palomera, E., Güell, E., Yébenes, J. C., Serra-Prat, M., Bermejo-Martín, J. F., Almirall, J., Tomas, E., Escoval, A., Froe, F., Pereira, M. H. Vitoria, Velez, N., Viegas, E., Filipe, E., Groves, C., Reay, M., Chiu, L. C., Hu, H. C., Hung, C. Y., Chang, C. H., Li, S. H., Kao, K. C., Ballin, A., Facchin, F., Sartori, G., Zarantonello, F., Campello, E., Radu, C. M., Rossi, S., Ori, C., Simioni, P., Umei, N., Shingo, I., Santos, A. C., Candeias, C., Moniz, I., Marçal, R., e Silva, Z. Costa, Ribeiro, J. M., Georger, J. F., Ponthus, J. P., Tchir, M., Amilien, V., Ayoub, M., Barsam, E., Martucci, G., Panarello, G., Tuzzolino, F., Capitanio, G., Ferrazza, V., Carollo, T., Giovanni, L., Arcadipane, A., Sánchez, M. López, González-Gay, M. A., Díaz, F. J. Llorca, López, M. I. Rubio, Zogheib, E., Villeret, L., Nader, J., Bernasinski, M., Besserve, P., Caus, T., Dupont, H., Morimont, P., Habran, S., Hubert, R., Desaive, T., Blaffart, F., Janssen, N., Guiot, J., Pironet, A., Dauby, P., Lambermont, B., Zarantonello, F., Ballin, A., Facchin, F., Sartori, G., Campello, E., Pettenuzzo, T., Citton, G., Rossi, S., Simioni, P., Ori, C., Kirakli, C., Ediboglu, O., Ataman, S., Yarici, M., Tuksavul, F., Keating, S., Gibson, A., Gilles, M., Dunn, M., Price, G., Young, N., Remeta, P., Bishop, P., Zamora, M. D. Fernández, Muñoz-Bono, J., Curiel-Balsera, E., Aguilar-Alonso, E., Hinojosa, R., Gordillo-Brenes, A., Arboleda-Sánchez, J. A., Skorniakov, I., Vikulova, D., Whiteley, C., Shaikh, O., Jones, A., Ostermann, M., Forni, L., Scott, M., Sahatjian, J., Linde-Zwirble, W., Hansell, D., Laoveeravat, P., Srisawat, N., Kongwibulwut, M., Peerapornrattana, S., Suwachittanont, N., Wirotwan, T. O., Chatkaew, P., Saeyub, P., Latthaprecha, K., Tiranathanagul, K., Eiam-ong, S., Kellum, J. A., Berthelsen, R. E., Perner, A., Jensen, A. E. K., Jensen, J. U., Bestle, M. H., Gebhard, D. J., Price, J., Kennedy, C. E., Akcan-Arikan, A., Liberatore, A. M. A., Souza, R. B., Martins, A. M. C. R. P. F., Vieira, J. C. F., Kang, Y. R., Nakamae, M. N., Koh, I. H. J., Hamed, K., Khaled, M. M., Soliman, R. Aly, Mokhtar, M. Sherif, Seller-Pérez, G., Arias-Verdú, D., Llopar-Valdor, E., De-Diós-Chacón, I., Quesada-García, G., Herrera-Gutierrez, M. E., Hafes, R., Carroll, G., Doherty, P., Wright, C., Vera, I. G. Guerra, Ralston, M., Gemmell, M. L., MacKay, A., Black, E., Wright, C., Docking, R. I., Appleton, R., Ralston, M. R., Gemmell, L., Appleton, R., Wright, C., Docking, R. I., Black, E., Mackay, A., Rozemeijer, S., Mulier, J. L. G. Haitsma, Röttgering, J. G., Elbers, P. W. G., Spoelstra-de Man, A. M. E., Tuinman, P. R., de Waard, M. C., Oudemans-van Straaten, H. M., Mejeni, N., Nsiala, J., Kilembe, A., Akilimali, P., Thomas, G., Egerod, I., Andersson, A. E., Fagerdahl, A. M., Knudsen, V., Meddeb, K., Cheikh, A. Ben, Hamdaoui, Y., Ayachi, J., Guiga, A., Fraj, N., Romdhani, S., Sma, N., Bouneb, R., Chouchene, I., Khedher, A., Bouafia, N., Boussarsar, M., Amirian, A., Ziaian, B., Masjedi, M., Fleischmann, C., Thomas-Rueddel, D. O., Schettler, A., Schwarzkopf, D., Stacke, A., Reinhart, K., Filipe, E., Escoval, A., Martins, A., Sousa, P., Velez, N., Viegas, E., Tomas, E., Snell, G., Matsa, R., Paary, T. T. S., Kalaiselvan, M. S., Cavalheiro, A. M., Rocha, L. L., Vallone, C. S., Tonilo, A., Lobato, M. D. S., Malheiro, D. T., Sussumo, G., Lucino, N. M., Zand, F., Rosenthal, V. D., Masjedi, M., Sabetian, G., Maghsudi, B., Ghorbani, M., Dashti, A. Sanaei, Yousefipour, A., Goodall, J. R., Williamson, M., Tant, E., Thomas, N., Balci, C., Gonen, C., Haftacı, E., Gurarda, H., Karaca, E., Paldusová, B., Zýková, I., Šímová, D., Houston, S., D’Antona, L., Lloyd, J., Garnelo-Rey, V., Sosic, M., Sotosek-Tokmazic, V., Kuharic, J., Antoncic, I., Dunatov, S., Sustic, A., Chong, C. T., Sim, M., Lyovarin, T., Díaz, F. M. Acosta, Galdó, S. Narbona, Garach, M. Muñoz, Romero, O. Moreno, Bailón, A. M. Pérez, Pinel, A. Carranza, Colmenero, M., Gritsan, A., Gazenkampf, A., Korchagin, E., Dovbish, N., Lee, R. M., Lim, M. P. P., Chong, C. T., Lim, B. C. L., See, J. J., Assis, R., Filipe, F., Lopes, N., Pessoa, L., Pereira, T., Catorze, N., Aydogan, M. S., Aldasoro, C., Marchio, P., Jorda, A., Mauricio, M. D., Guerra-Ojeda, S., Gimeno-Raga, M., Colque-Cano, M., Bertomeu-Artecero, A., Aldasoro, M., Valles, S. L., Tonon, D., Triglia, T., Martin, J. C., Alessi, M. C., Bruder, N., Garrigue, P., Velly, L., Spina, S., Scaravilli, V., Marzorati, C., Colombo, E., Savo, D., Vargiolu, A., Cavenaghi, G., Citerio, G., Andrade, A. H. V., Bulgarelli, P., Araujo, J. A. P., Gonzalez, V., Souza, V. A., Costa, A., Massant, C., Filho, C. A. C. Abreu, Morbeck, R. A., Burgo, L. E., van Groenendael, R., van Eijk, L. T., Leijte, G. P., Koeneman, B., Kox, M., Pickkers, P., García-de la Torre, A., de la Torre-Prados, M., Fernández-Porcel, A., Rueda-Molina, C., Nuevo-Ortega, P., Tsvetanova-Spasova, T., Cámara-Sola, E., García-Alcántara, A., Salido-Díaz, L., Liao, X., Feng, T., Zhang, J., Cao, X., Wu, Q., Xie, Z., Li, H., Kang, Y., Winkler, M. S., Nierhaus, A., Mudersbach, E., Bauer, A., Robbe, L., Zahrte, C., Schwedhelm, E., Kluge, S., Zöllner, C., Morton, B., Mitsi, E., Pennington, S. H., Reine, J., Wright, A. D., Parker, R., Welters, I. D., Blakey, J. D., Rajam, G., Ades, E. W., Ferreira, D. M., Wang, D., Kadioglu, A., Gordon, S. B., Koch, R., Kox, M., Rahamat-Langedoen, J., Schloesser, J., de Jonge, M., Pickkers, P., Bringue, J., Guillamat-Prats, R., Torrents, E., Martinez, M. L., Camprubí-Rimblas, M., Artigas, A., Blanch, L., Park, S. Y., Park, Y. B., Song, D. K., Shrestha, S., Park, S. H., Koh, Y., Park, M. J., Hong, C. W., Lesur, O., Coquerel, D., Sainsily, X., Cote, J., Söllradl, T., Murza, A., Dumont, L., Dumaine, R., Grandbois, M., Sarret, P., Marsault, E., Salvail, D., Auger-Messier, M., Chagnon, F., Lauretta, M. P., Greco, E., Dyson, A., Singer, M., Preau, S., Ambler, M., Sigurta, A., Saeed, S., Singer, M., Sarıca, L. Topcu, Zibandeh, N., Genc, D., Gul, F., Akkoc, T., Kombak, E., Cinel, L., Akkoc, T., Cinel, I., Pollen, S. J., Arulkumaran, N., Singer, M., Torrance, H. D., Longbottom, E. R., Warnes, G., Hinds, C. J., Pennington, D. J., Brohi, K., O’Dwyer, M. J., Kim, H. Y., Na, S., Kim, J., Chang, Y. F., Chao, A., Shih, P. Y., Lee, C. T., Yeh, Y. C., Chen, L. W., Adriaanse, M., Trogrlic, Z., Ista, E., Lingsma, H., Rietdijk, W., Ponssen, H. H., Schoonderbeek, J. F., Schreiner, F., Verbrugge, S. J., Duran, S., Gommers, D. A. M. P. J., van der Jagt, M., Funcke, S., Sauerlaender, S., Saugel, B., Pinnschmidt, H., Reuter, D. A., Nitzschke, R., Perbet, S., Biboulet, C., Lenoire, A., Bourdeaux, D., Pereira, B., Plaud, B., Bazin, J. E., Sautou, V., Mebazaa, A., Constantin, J. M., Legrand, M., Boyko, Y., Jennum, P., Nikolic, M., Oerding, H., Holst, R., Toft, P., Nedergaard, H. K., Haberlandt, T., Jensen, H. I., Toft, P., Park, S., Kim, S., Cho, Y. J., Lim, Y. J., Chan, A., Tang, S., Nunes, S. L., Forsberg, S., Blomqvist, H., Berggren, L., Sörberg, M., Sarapohja, T., Wickerts, C. J., Hofhuis, J. G. M., Rose, L., Blackwood, B., Akerman, E., Mcgaughey, J., Egerod, I., Fossum, M., Foss, H., Georgiou, E., Graff, H. J., Kalafati, M., Sperlinga, R., Schafer, A., Wojnicka, A. G., Spronk, P. 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Bermejo, Mudarra-Reche, C., Xu, W., Chico-Fernández, M., Montejo-González, J. C., Crewdson, K., Thomas, M., Merghani, M., Fenner, L., Morgan, P., Lockey, D., van Lieshout, E. J., Oomen, B., Binnekade, J. M., Dongelmans, D. A., de Haan, R. J., Juffermans, N. P., Vroom, M. B., Algarte, R., Martínez, L., Sánchez, B., Romero, I., Martínez, F., Quintana, S., Trenado, J., Sheikh, O., Pogson, D., Clinton, R., Riccio, F., Gemmell, L., MacKay, A., Arthur, A., Young, L., Sinclair, A., Markopoulou, D., Venetsanou, K., Filippou, L., Salla, E., Stratouli, S., Alamanos, I., Guirgis, A. H., Rodriguez, R. Gutiérrez, Lorente, M. J. Furones, Guarasa, I. Macias, Ukere, A., Meisner, S., Greiwe, G., Opitz, B., Benten, D., Nashan, B., Fischer, L., Trepte, C. J. C., Reuter, D. A., Haas, S. A., Behem, C. R., Tavazzi, G., Ana, B., Vazir, A., Gibson, D., Price, S., Masjedi, M., Hadavi, M. R., alam, M. Riahi, Sasani, M. R., Parenti, N., Agrusta, F., Palazzi, C., Pifferi, B., Sganzerla, R., Tagliazucchi, F., Luciani, A., Möller, M., Müller-Engelmann, J., Montag, G., Adams, P., Lange, C., Neuzner, J., Gradaus, R., Wodack, K. H., Thürk, F., Waldmann, A. D., Grässler, M. F., Nishimoto, S., Böhm, S. H., Kaniusas, E., Reuter, D. A., Trepte, C. J., Sigmundsson, T., Öhman, T., Redondo, E., Hallbäck, M., Wallin, M., Sipman, F. Suarez, Oldner, A., Sander, C. Hällsjö, Björne, H., Colinas, L., Hernandez, G., Vicho, R., Serna, M., Cuena, R., Canabal, A., Chaari, A., Hakim, K. Abdel, Etman, M., El Bahr, M., El Sakka, A., Bousselmi, K., Arali, A., Kauts, V., Casey, W. F., Bond, O., De Santis, P., Iesu, E., Franchi, F., Vincent, J. L., Creteur, J., Scolletta, S., Taccone, F. S., Marutyan, Z., Hamidova, L., Shakotko, A., Movsisyan, V., Uysupova, I., Evdokimov, A., Petrikov, S., Gonen, C., Haftacı, E., Balci, C., Calvo, F. J. Redondo, Bejarano, N., Baladron, V., Villazala, R., Redondo, J., Padilla, D., Villarejo, P., Akcan-Arikan, A., Kennedy, C. E., Arzapalo, M. F. Aguilar, Gomez-Gonzalez, C., Mas-Font, S., Puppo-Moreno, A., Herrera-Gutierrez, M., Garcia-Garcia, M., Aldunate-Calvo, S., Plata-Menchaca, E. P., Pérez-Fernández, X. L., Estruch, M., Betbese-Roig, A., Campos, P. Cárdenas, Lora, M. Rojas, Gaibor, N. D. Toapanta, Medina, R. S. Contreras, Sanguino, V. D. Gumucio, Casanova, E. J., Riera, J. Sabater, Kritmetapak, K., Peerapornratana, S., Kittiskulnam, P., Dissayabutra, T., Tiranathanagul, K., Susantithapong, P., Praditpornsilpa, K., Tungsanga, K., Eiam-Ong, S., Srisawat, N., Winkelmann, T., Busch, T., Meixensberger, J., Bercker, S., Cabeza, E. M. Flores, Sánchez, M. Sánchez, Giménez, N. Cáceres, Melón, C. Gutierrez, de Lucas, E. Herrero, Estañ, P. Millán, Bernal, M. Hernández, de Lorenzo y Mateos, A. Garcia, Ergin, B., Guerci, P., Specht, P. A. C., Ince, Y., Ince, C., Balik, M., Zakharchenko, M., Los, F., Brodska, H., de Tymowski, C., Augustin, P., Desmard, M., Montravers, P., Stapel, S. N., de Boer, R., Oudemans, H. M., Hollinger, A., Schweingruber, T., Jockers, F., Dickenmann, M., Siegemund, M., Runciman, N., Ralston, M., Appleton, R., Mauri, T., Alban, L., Turrini, C., Sasso, T., Langer, T., Panigada, M., Taccone, P., Carlesso, E., Marenghi, C., Grasselli, G., Pesenti, A., Wibart, P., Reginault, T., Garcia, M., Barbrel, B., Benard, A., Bader, C., Vargas, F., Bui, H. N., Hilbert, G., Simón, J. M. Serrano, Sánchez, P. Carmona, Ferrón, F. Ruiz, de Acilu, M. García, Marin, J., Antonia, V., Ruano, L., Monica, M., Ferrer, R., Masclans, J. R., Roca, O., Hong, G., Kim, D. H., Kim, Y. S., Park, J. S., Jee, Y. K., xiang, Z. Yu, Jia-xing, W., dan, W. Xiao, long, N. Wen, Yu, W., Yan, Z., Cheng, X., Kobayashi, T., Onodera, Y., Akimoto, R., Sugiura, A., Suzuki, H., Iwabuchi, M., Nakane, M., Kawamae, K., Sanchez, P. Carmona, Rodriguez, M. D. Bautista, Delgado, M. Rodriguez, Sánchez, V. Martínez de Pinillos, Gómez, A. Mula, Simón, J. M. Serrano, Beuret, P., Fortes, C., Lauer, M., Reboul, M., Chakarian, J. C., Fabre, X., Philippon-Jouve, B., Devillez, S., Clerc, M., Rittayamai, N., Sklar, M., Dres, M., Rauseo, M., Campbell, C., West, B., Tullis, D. E., Brochard, L., Onodera, Y., Akimoto, R., Suzuki, H., Okada, M., Nakane, M., Kawamae, K., Ahmad, N., Wood, M., Glossop, A., Lucas, J. Higuera, Ortiz, A. Blandino, Alonso, D. Cabestrero, De Pablo Sánchez, R., González, L. Rey, Costa, R., Spinazzola, G., Pizza, A., Ferrone, G., Rossi, M., Antonelli, M., Conti, G., Ribeiro, H., Alves, J., Sousa, M., Reis, P., Socolovsky, C. S., Cauley, R. P., Frankel, J. E., Beam, A. L., Olaniran, K. O., Gibbons, F. K., Christopher, K. B., Pennington, J., Zolfaghari, P., King, H. S., Kong, H. H. Y., Shum, H. P., Yan, W. W., Kaymak, C., Okumus, N., Sari, A., Erdogdu, B., Aksun, S., Basar, H., Ozcan, A., Ozcan, N., Oztuna, D., Malmgren, J. A., Lundin, S., Torén, K., Eckerström, M., Wallin, A., Waldenström, A. C., Riccio, F. C., Pogson, D., Antonio, A. C. P., Leivas, A. F., Kenji, F., James, E., Morgan, P., Carroll, G., Gemmell, L., MacKay, A., Wright, C., Ballantyne, J., Jonnada, S., Gerrard, C. S., Jones, N., Salciccioli, J. D., Marshall, D. C., Komorowski, M., Hartley, A., Sykes, M. C., Goodson, R., Shalhoub, J., Villanueva, J. R. Fernández, Garda, R. Fernández, Lago, A. M. López, Ruiz, E. Rodríguez, Vaquero, R. Hernández, Rodríguez, C. Galbán, Pérez, E. Varo, Hilasque, C., Oliva, I., Sirgo, G., Martin, M. C., Olona, M., Gilavert, M. C., Bodí, M., Ebm, C., Aggarwal, G., Huddart, S., Quiney, N., Cecconi, M., Fernandes, S. M., Silva, J. Santos, Gouveia, J., Silva, D., Marques, R., Bento, H., Alvarez, A., Silva, Z. Costa, Diaz, D. Díaz, Martínez, M. Villanova, Herrejon, E. Palencia, de la Gandara, A. Martinez, Gonzalo, G., Lopez, M. A., de Gopegui Miguelena, P. Ruíz, Matilla, C. I. Bernal, Chueca, P. Sánchez, Longares, M. D. C. Rodríguez, Abril, R. Ramos, Aguilar, A. L. Ruíz, de Murillas, R. Garrido López, Fernández, R. Fernández, Laborías, P. Morales, Castellanos, M. A. Díaz, Laborías, M. E. Morales, Cho, J., Kim, J., Park, J., Woo, S., West, T., Powell, E., Rimmer, A., Orford, C., Jones, N., Williams, J., Matilla, C. I. Bernal, de Gopegui Miguelena, P. Ruiz, Chueca, P. Sánchez, Abril, R. Ramos, Longares, M. D. C. Rodríguez, Aguilar, A. L. Ruíz, de Murillas, R. Garrido López, Bourne, R. S., Shulman, R., Tomlin, M., Mills, G. H., Borthwick, M., Berry, W., Huertas, D. García, Manzano, F., Villagrán-Ramírez, F., Ruiz-Perea, A., Rodríguez-Mejías, C., Santiago-Ruiz, F., Colmenero-Ruiz, M., König, C., Matt, B., Kortgen, A., Hartog, C. S., Wong, A., Balan, C., Barker, G., Srisawat, N., Peerapornratana, S., Laoveeravat, P., Tachaboon, S., Eiam-ong, S., Paratz, J., Kayambu, G., Boots, R., Arzapalo, M. F. Aguilar, Vlasenko, R., Gromova, E., Loginov, S., Kiselevskiy, M., Dolgikova, Y., Tang, K. B., Chau, C. M., Lam, K. N., Gil, E., Suh, G. Y., Park, C. M., Park, J., Chung, C. R., Lee, C. T., Chao, A., Shih, P. Y., Chang, Y. F., Lai, C. H., Hsu, Y. C., Yeh, Y. C., Cheng, Y. J., Colella, V., Zarrillo, N., D’Amico, M., Forfori, F., Pezza, B., Laddomada, T., Beltramelli, V., Pizzaballa, M. L., Doronzio, A., Balicco, B., Kiers, D., van der Heijden, W., Gerretsen, J., de Mast, Q., el Messaoudi, S., Rongen, G., Gomes, M., Kox, M., Pickkers, P., Riksen, N. P., Kashiwagi, Y., Okada, M., Hayashi, K., Inagaki, Y., Fujita, S., Nakamae, M. N., Kang, Y. R., Souza, R. B., Liberatore, A. M. A., Koh, I. H. J., Blet, A., Sadoune, M., Lemarié, J., Bihry, N., Bern, R., Polidano, E., Merval, R., Launay, J. M., Lévy, B., Samuel, J. L., Mebazaa, A., Hartmann, J., Harm, S., and Weber, V.
- Published
- 2016
- Full Text
- View/download PDF
11. Tyrosine and Tryptophan Derivatives in Pig Lumbar Cerebrospinal Fluid : Effects of Subchronic Administration of Dopa Associated with Benzeraside
- Author
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Banting, S., Achilli, G., Banting, A., Le Bars, D., Weil-Fugazza, J., Filippini, Graziella Allegri, editor, Costa, Carlo V. L., editor, and Bertazzo, Antonella, editor
- Published
- 1996
- Full Text
- View/download PDF
12. Quelle est la validité conceptuelle des tests et modèles animaux de douleurs ?
- Author
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Le Bars, D., Pollin, B., and Plaghki, L.
- Published
- 2012
- Full Text
- View/download PDF
13. Une approche de la douleur expérimentale commune à l’homme et à l’animal
- Author
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Le Bars, D., Pollin, B., and Plaghki, L.
- Published
- 2011
- Full Text
- View/download PDF
14. A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease
- Author
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Truchot, L., Costes, N., Zimmer, L., Laurent, B., Le Bars, D., Thomas-Antérion, C., Mercier, B., Hermier, M., Vighetto, A., and Krolak-Salmon, P.
- Published
- 2008
- Full Text
- View/download PDF
15. Plasticità del dolore: ruolo dei controlli inibitori diffusi
- Author
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Le Bars, D. and Willer, J.-C.
- Published
- 2008
- Full Text
- View/download PDF
16. Le fluor 18 en radiopharmacie
- Author
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de Beco, V., Le Bars, D., and Scherrmann, J.-M.
- Published
- 2008
- Full Text
- View/download PDF
17. Motor urgency is mediated by the contralateral cerebellum in Parkinson's disease
- Author
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Ballanger, B., Baraduc, P., Broussolle, E., Le Bars, D., Desmurget, M., and Thobois, S.
- Subjects
Parkinson's disease -- Development and progression ,Parkinson's disease -- Research ,Motor ability -- Research ,Cerebellum -- Physiological aspects ,Cerebellum -- Research ,Health ,Psychology and mental health - Published
- 2008
18. High and Low Grade Oligodendrogliomas (ODG): Correlation of Amino-Acid and Glucose Uptakes Using PET and Histological Classifications
- Author
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Giammarile, F., Cinotti, L.E., Jouvet, A., Ramackers, J.M., Pierre, G. Saint, Thiesse, P., Jouanneau, E., Guyotat, J., Pelissou-Guyotat, I., Setiey, A., Honnorat, J., Le Bars, D., and Frappaz, D.
- Published
- 2004
- Full Text
- View/download PDF
19. [11C]-Methionine PET: dysembryoplastic neuroepithelial tumours compared with other epileptogenic brain neoplasms
- Author
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Rosenberg, D.S., Demarquay, G., Jouvet, A., Le Bars, D., Streichenberger, N., Sindou, M., Kopp, N., Mauguiere, F., and Ryvlin, P.
- Subjects
Methionine -- Usage ,PET imaging -- Usage ,Health ,Psychology and mental health - Published
- 2005
20. Chronic subthalamic nucleus stimulation and striatal D2 dopamine receptors in Parkinson’s disease: A[11C]-raclopride PETstudy
- Author
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Thobois, S., Fraix, V., Savasta, M., Costes, N., Pollak, P., Mertens, P., Koudsie, A., Le Bars, D., Benabid, A. L., and Broussolle, E.
- Published
- 2003
- Full Text
- View/download PDF
21. Relations entre pathologies psychiatriques et douleur: une approche chez l’animal?
- Author
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André, J., Becker, Ch., Zeau, B., Le Bars, D., Hamon, M., Cesselin, F., and Benolil, J.- J.
- Published
- 2003
- Full Text
- View/download PDF
22. Mechanical allodynia in neuropathic pain. Where are the brain representations located? A positron emission tomography (PET) study
- Author
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Peyron, R., Faillenot, I., Pomares, F. B., Le Bars, D., Garcia-Larrea, L., and Laurent, B.
- Published
- 2013
- Full Text
- View/download PDF
23. The potential of the β-Microprobe, an intracerebral radiosensitive probe, to monitor the [18F]MPPF binding in the rat dorsal raphe nucleus
- Author
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Zimmer, L., Pain, F., Mauger, G., Plenevaux, A., Le Bars, D., Mastrippolito, R., Pujol, J., Renaud, B., and Lanièce, P.
- Published
- 2002
- Full Text
- View/download PDF
24. Regard critique sur les modèles animaux de douleur aiguë
- Author
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Le Bars, D.
- Published
- 2001
- Full Text
- View/download PDF
25. Sommation spatiale et codage médullaire de l’information nociceptive
- Author
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Gall, O., Bouhassira, D., Chitour, D., and Le Bars, D.
- Published
- 1999
- Full Text
- View/download PDF
26. What is a Wide-Dynamic-Range Cell?
- Author
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Le Bars, D., primary and Cadden, S.W., additional
- Published
- 2008
- Full Text
- View/download PDF
27. Diffuse Noxious Inhibitory Controls (DNIC)
- Author
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Le Bars, D., primary and Willer, J.C., additional
- Published
- 2008
- Full Text
- View/download PDF
28. Adaptation to uncertain sea-level rise; how uncertainty in Antarctic mass-loss impacts the coastal adaptation strategy of the Netherlands
- Author
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Haasnoot, M, primary, Kwadijk, J, additional, van Alphen, J, additional, Le Bars, D, additional, van den Hurk, B, additional, Diermanse, F, additional, van der Spek, A, additional, Essink, G Oude, additional, Delsman, J, additional, and Mens, M, additional
- Published
- 2020
- Full Text
- View/download PDF
29. P.322 Progression of dopaminergic and serotonergic dysfunction related to neuropsychiatric signs in Parkinson's disease
- Author
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Prange, S., primary, Metereau, E., additional, Klinger, H., additional, Schmitt, E., additional, Lhommée, E., additional, Bichon, A., additional, Le Bars, D., additional, Maillet, A., additional, Pelissier, P., additional, Meoni, S., additional, Broussolle, E., additional, Castrioto, A., additional, Krack, P., additional, and Thobois, S., additional
- Published
- 2020
- Full Text
- View/download PDF
30. Fisiología del dolor
- Author
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Le Bars, D. and Willer, J.-C.
- Published
- 2005
- Full Text
- View/download PDF
31. Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism
- Author
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Le Bars, D. and Yvon, M.
- Published
- 2008
32. Physiologie de la douleur
- Author
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Le Bars, D. and Willer, J.-C.
- Published
- 2004
- Full Text
- View/download PDF
33. Tissue Distribution, Autoradiography, and Metabolism of 4-(2′-Methoxyphenyl)-1-[2′-[N-(2"-Pyridinyl)-p-[18F]Fluorobenzamido]ethyl]piperazine (p-[18F]MPPF), a New Serotonin 5-HT1A Antagonist for Positron Emission Tomography: An In Vivo Study in Rats
- Author
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Plenevaux, A., Weissmann, D., Aerts, J., Lemaire, C., Brihaye, C., Degueldre, C., Le Bars, D., Comar, D., Pujol, J.-F., and Luxen, A.
- Published
- 2000
34. An observed 20-year time series of Agulhas leakage
- Author
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Le Bars, D., Durgadoo, J. V., Dijkstra, H. A., Biastoch, A., De Ruijter, W. P M, Sub Physical Oceanography, Marine and Atmospheric Research, Sub Physical Oceanography, and Marine and Atmospheric Research
- Subjects
lcsh:GE1-350 ,Palaeontology ,lcsh:Geography. Anthropology. Recreation ,Agulhas current ,Geodesy ,Oceanography ,symbols.namesake ,Ocean surface topography ,lcsh:G ,13. Climate action ,Return current ,Satellite altimetry ,Climatology ,symbols ,Vector field ,Geology ,Geostrophic wind ,Lagrangian ,lcsh:Environmental sciences ,Leakage (electronics) - Abstract
We provide a time series of Agulhas leakage anomalies over the last 20-years from satellite altimetry. Until now, measuring the interannual variability of Indo-Atlantic exchange has been the major barrier in the investigation of the dynamics and large scale impact of Agulhas leakage. We compute the difference of transport between the Agulhas Current and Agulhas Return Current, which allows us to deduce Agulhas leakage. The main difficulty is to separate the Agulhas Return Current from the southern limb of the subtropical "supergyre" south of Africa. For this purpose, an algorithm that uses absolute dynamic topography data is developed. The algorithm is applied to a state-of-the-art ocean model. The comparison with a Lagrangian method to measure the leakage allows us to validate the new method. An important result is that it is possible to measure Agulhas leakage in this model using the velocity field along a section that crosses both the Agulhas Current and the Agulhas Return Current. In the model a good correlation is found between measuring leakage using the full depth velocities and using only the surface geostrophic velocities. This allows us to extend the method to along-track absolute dynamic topography from satellites. It is shown that the accuracy of the mean dynamic topography does not allow us to determine the mean leakage but that leakage anomalies can be accurately computed.
- Published
- 2018
35. Intracerebroventricular morphine, analgesia, and nociceptive spinal reflexes
- Author
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Blond, S, Guieu, J D, Meynadier, J, Le Bars, D, and Willer, J C
- Published
- 1994
36. [ 18F] p-MPPF: A Radiolabeled Antagonist for the Study of 5-HT 1A Receptors with PET
- Author
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Plenevaux, A, Lemaire, C, Aerts, J, Lacan, G, Rubins, D, Melega, W.P, Brihaye, C, Degueldre, C, Fuchs, S, Salmon, E, Maquet, P, Laureys, S, Damhaut, P, Weissmann, D, Le Bars, D, Pujol, J.-F, and Luxen, A
- Published
- 2000
- Full Text
- View/download PDF
37. Diffuse noxious inhibitory controls in man: involvement of the spinoreticular tract
- Author
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De Broucker, Th., Cesaro, P., Willer, J.C., and Le Bars, D.
- Subjects
Pain -- Physiological aspects ,Reflexes -- Physiological aspects ,Health - Abstract
Since the inner workings of the human brain and spinal cord cannot be observed directly, they must be inferred from the accumulation of experimental results and clinical observations. It has been observed that the electrical stimulation of the sural nerve in the ankle results in pain and a pain-avoidance reflex. The reflex, called RIII, and the painful sensation can be depressed by the application of painful stimuli to another remote region of the body, such as the fingers. The application of a non-painful stimulus to a remote region of the body is ineffective in depressing the painful results of the ankle stimulation. To determine if this effect requires the brain, or if only the spinal cord is necessary, this test was performed on quadriplegic patients with spinal cord damage. The depression was ineffective in these patients, indicating that the part of the nervous system responsible for the effect lies above the neck. To further identify the part of the nervous system responsible for this pain suppression, the test was repeated on three patients with damage to the thalamus and three patients with Wallenberg's syndrome, which involves unilateral damage to the brainstem. The patients with the lesions in the thalamus, who could feel the sensation on the hand as noxious but not as painful, displayed an inhibition of the reflex similar to that seen in normal controls. However, the patients with Wallenberg's syndrome showed no such inhibition. The authors feel that the inhibition of the pain and the pain-avoidance reflex cannot be explained simply by the diversion of attention. The researchers believe that these findings suggest that the lemniscal and spinothalamic nerve pathways cannot be involved in the pain inhibition, and suggest that the brainstem and the spinoreticular nerve tract are likely to be involved. (Consumer Summary produced by Reliance Medical Information, Inc.)
- Published
- 1990
38. Douleur et thermorégulation Les effets ambivalents de la morphine
- Author
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El Bitar, N., primary and Le Bars, D., additional
- Published
- 2018
- Full Text
- View/download PDF
39. Fisiología del dolor
- Author
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Plaghki, L., primary, Mouraux, A., additional, and Le Bars, D., additional
- Published
- 2018
- Full Text
- View/download PDF
40. Bases neurophysiologiques du phénomène de contre-irritation: les contrôles inhibiteurs diffus induits par stimulations nociceptives
- Author
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Willer, J.C., Bouhassira, D., and Le Bars, D.
- Published
- 1999
- Full Text
- View/download PDF
41. Electrical stimulation of motor cortex for pain control: a combined PET-scan and electrophysiological study
- Author
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Garcı́a-Larrea, L, Peyron, R, Mertens, P, Gregoire, M.C, Lavenne, F, Le Bars, D, Convers, P, Mauguière, F, Sindou, M, and Laurent, B
- Published
- 1999
- Full Text
- View/download PDF
42. Neurophysiological Mechanisms Involved in the Pain-Relieving Effects of Counterirritation and Related Techniques Including Acupuncture
- Author
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Le Bars, D., Willer, J. C., de Broucker, T., Villanueva, L., Pomeranz, Bruce, editor, and Stux, Gabriel, editor
- Published
- 1989
- Full Text
- View/download PDF
43. A Southern Ocean mode of multidecadal variability
- Author
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Le Bars, D., Viebahn, J. P., Dijkstra, H. A., Sub Physical Oceanography, Dep Natuurkunde, and Marine and Atmospheric Research
- Subjects
Geophysics ,ocean heat content ,Taverne ,baroclinic instability ,Earth and Planetary Sciences(all) ,intrinsic variability ,mode of variability ,Southern Ocean ,multidecadal variability - Abstract
A 250 year simulation of a strongly eddying global version of the Parallel Ocean Program (POP) model reveals a new mode of intrinsic multidecadal variability, the Southern Ocean Mode (SOM), with a period of 40-50 year. The peak-to-peak difference in the global ocean heat content within a multidecadal cycle is up to 60 ZJ. This change results from surface heat flux variations in the South Atlantic and propagation of temperature anomalies along the Antarctic Circumpolar Current and into the Weddell gyre around 30°E. The temperature anomalies propagate as deep as 5000 m along the isopycnals between 50°S and 30°S and induce multidecadal changes in the Atlantic Meridional Overturning Circulation. A positive feedback loop between the generation of eddies through baroclinic instability and the dynamics of the mean circulation is essential for the existence of the SOM. The dominant physics appears similar to that responsible for variability found in a three-layer quasi-geostrophic eddy-resolving model. This combined with the fact that the SOM is not found in a noneddying version of the same global POP model further suggests that eddy processes are crucial for its existence and/or excitation.
- Published
- 2016
44. Exploration of the concept of 5-HT1A receptor biased agonists: a multimodal imaging study
- Author
-
Vidal, B., primary, Fieux, S., additional, Redouté, J., additional, Villien, M., additional, Le Bars, D., additional, Newman-Tancredi, A., additional, Costes, N., additional, and Zimmer, L., additional
- Published
- 2017
- Full Text
- View/download PDF
45. Online transcranial direct current stimulation of the frontal cortex induces dopamine release in the striatum – a spatial and temporal analysis in healthy humans
- Author
-
Fonteneau, C., primary, Haesebaert, F., additional, Redoute, J., additional, Le Bars, D., additional, Costes, N., additional, Brunelin, J., additional, and Suaud-Chagny, M.F., additional
- Published
- 2017
- Full Text
- View/download PDF
46. Representing Greenland ice sheet freshwater fluxes in climate models
- Author
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Lenaerts, J.T.M., Le Bars, D., Van Kampenhout, L., Vizcaino, M., Enderlin, E.M., and Van den Broeke, M.R.
- Abstract
Here we present a long-term (1850–2200) best estimate of Greenland ice sheet (GrIS) freshwater runoff that improves spatial detail of runoff locations and temporal resolution. Ice discharge is taken from observations since 2000 and assumed constant in time. Surface meltwater runoff is retrieved from regional climate model output for the recent past and parameterized for the future based on significant correlations between runoff and midtropospheric (500 hPa) summer temperature changes over the GrIS. The simplicity of this approach enables assimilation of meltwater runoff into coupled climate models, which is demonstrated here in a case study with the medium-resolution (1?) Community Earth System Model. The model results suggest that the decrease in Atlantic Meridional Overturning Circulation (AMOC) is dominated by warming of the surface ocean and enhanced GrIS freshwater forcing leads to a slightly enhanced (?1.2 sverdrup in the 21st century) weakening of the AMOC.
- Published
- 2015
47. A Southern Ocean mode of multidecadal variability
- Author
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Sub Physical Oceanography, Dep Natuurkunde, Marine and Atmospheric Research, Le Bars, D., Viebahn, J. P., Dijkstra, H. A., Sub Physical Oceanography, Dep Natuurkunde, Marine and Atmospheric Research, Le Bars, D., Viebahn, J. P., and Dijkstra, H. A.
- Published
- 2016
48. PET radiotracers for molecular imaging of serotonin 5-HT1A receptors
- Author
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Billard, T., Le Bars, D., Zimmer, L., Synthèse, Utilisation, Réactivité des Composés Organiques et OrganoFluorés (SURCOOF), Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut de Chimie du CNRS (INC)-École Supérieure Chimie Physique Électronique de Lyon-Centre National de la Recherche Scientifique (CNRS), Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant), Université de Lyon-Université de Lyon-CHU Grenoble-Hospices Civils de Lyon (HCL)-CHU Saint-Etienne-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre de recherche en neurosciences de Lyon (CRNL), and Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging - Abstract
International audience; Serotonin and its various receptors are involved in numerous brain functions and neuropsychiatric disorders. The 5-HT1A family is the best characterized subtype of the fourteen currently known 5-HT receptors. The 5-HT1A receptor is closely involved in the pathogenesis of anxiety, depression, epilepsy and eating disorders and therefore is an important target for drug therapy. The development in the 1980s of molecules specifically targeting this receptor was followed by the rapid development of corresponding PET neuroimaging. Because this receptor represents a crucial target in neuroscience, a large number of radioligands have been developed by academic and industry centers for visualization and quantification, first in living animals and ultimately in humans. After a brief account of some of the structural and functional characteristics of brain 5-HT1A receptors, this review focuses on the main lines of evolution opened up by preclinical and clinical 5-HT1A PET radiopharmaceuticals, illustrating the potential value of PET for clinical research and drug development.
- Published
- 2014
- Full Text
- View/download PDF
49. Markers of vulnerable plaques in non-human primates under atherogenic diet
- Author
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di cataldo, V., primary, Agudelo, J. Piraquive, additional, Geloen, A., additional, Verset, M., additional, Paturet, A., additional, Serusclat, A., additional, Lamberton, F., additional, Ibarolla, D., additional, Lavenne, F., additional, Le Bars, D., additional, Contamin, H., additional, and Canet-Soulas, E., additional
- Published
- 2016
- Full Text
- View/download PDF
50. A Southern Ocean mode of multidecadal variability
- Author
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Le Bars, D., primary, Viebahn, J. P., additional, and Dijkstra, H. A., additional
- Published
- 2016
- Full Text
- View/download PDF
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