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Morphometric analysis is the quantification of shapes, which makes irregular shapes found in nature analyzable and comparable. Cave morphometry has been used for the genetic classification of caves, the digital reconstruction of their conduits, the decoding of their paleoenvironment, and other research purposes. Ratios and indices that have been derived from Euclidean geometry and application of fractal geometry onto karst features and topological parameters are the basic methodologies that have been used for shape quantification. This paper reviews the literature that focuses on methodologies used for morphometric analyses and the applications that these methodologies have found. [ABSTRACT FROM AUTHOR]

Mediterranean Diet is globally recognized as a healthy eating model that relates to the cultural heritage of countries in the Mediterranean basin. The purpose of this study is to provide evidence of the relationship between attitudes, culinary motivation, and the intention to experience the Mediterranean Diet while visiting Greece. By implementing a quantitative, cross-sectional methodology, an online questionnaire was developed based on existing literature. Data analysis included descriptive statistics, inferential statistics, and regression analysis. To this end, data derived from a sample of 1,692 tourists revealed varying attitudes toward local food and gastronomy, along with heterogeneous culinary motives which influenced their intention to experience the Mediterranean Diet. Tourists who chose their destination based on food options and displayed a heightened interest and knowledge of food and gastronomy were more likely to experience the Mediterranean Diet during their stay. Health concerns and cultural experience emerged as the most significant motivational factors. Several actions are recommended to promote the Mediterranean Diet as a lever for culinary tourism. [ABSTRACT FROM AUTHOR]

Caves serve as time capsules, preserving significant markers of tectonic activity and offering insights into geological history. Fault geometries and past activations found in caves can be correlated with known deformational events in the broader area, temporally delimiting the speleogenesis. More specifically, cave passage formation is suggested to be affected by the regional stress-field. The Asprorema Cave in Northern Greece is a typical example of a fracture guided cave, with passage geometry influenced by relative sidewall movements, revealing these discontinuities as faults. This study constructs the timeframe and conceptual model of speleogenesis in relation to tectonic events, geomorphological evolution and hydrological zones, and verifies its relation to the stress-field. Active tectonics, mineralogy and cave geomorphology are investigated. Results suggest syntectonic speleogenesis under phreatic and epiphreatic conditions. The absence of corrosion on fault slip surfaces implies recent activations post cave's shift to the vadose zone. Structural analysis identifies three main neotectonic phases: NNW-SSE striking faults (oldest group of structures), NE-SW striking faults with dextral strike-slip movement (post-middle Miocene), and NE-SW striking normal faults indicating extensional stress-regime (Quartenary). The last two phases affect cave passage shape causing wall displacement, highlighting passage formation along discontinuities perpendicular to the horizontal minimum stress axis. [ABSTRACT FROM AUTHOR]

Characterized by an aggressive clinical course and relatively poor prognosis, triple-negative breast cancer (TNBC) refers to a diverse group of tumors with distinct molecular characteristics rather than to a single entity. The recognition of distinct gene expression subtypes within the group of TNBC and the description of an ever-expanding set of genetic events has led to improved understanding of the underlying biology. However, the improvement of clinical results has been incremental despite undergoing efforts to evaluate the role of molecularly targeted agents in the treatment of TNBC. The relative rarity of each one of these genetic events increases the difficulty of conducting large clinical trials, further hindering our ability to identify meaningful, personalized treatment approaches. Herein, we summarize current knowledge on TNBC, focusing on molecular pathology and emerging treatment approaches.

Iron oxide deposits in the form of crusts are examined in the field and in the laboratory with scanning electron microscopy. Samples came from two caves developed in different geological settings but assumed by previous studies to be of hydrothermal-hypogene origin. The relation of iron oxide crusts to cave wall and ceiling morphology created by the cave's primary dissolution (speleogenesis), as well as to the formation of other speleothems, is investigated. Scanning electron microscope (SEM) elemental analysis showed a high iron content (20-78 % by weight) consistent with iron oxide minerals such as goethite, hematite, magnetite, etc. Three distinct types of iron oxide crusts were identified from the four samples that were analyzed: (1) high iron content crusts with some porosity formed on the host rock surface and discontinuities, (2) high iron content (but lower than type 1) crusts, including limestone clasts and pores originating from dissolved clasts, and (3) high iron content, significantly-porous crusts that are formed by a network of filaments that indicate microbial activity. The formation of these deposits in relation to other speleothems and to dissolution events is discussed. [ABSTRACT FROM AUTHOR]

Firn from an ice cave in the highest mountain of Greece, Mount Olympus, was sampled and analyzed to determine the tritium content in order to estimate rates of accumulation and to date the ice plug. The presence of a sharp raise of tritium content indicating the nuclear testing era was expected to be preserved into ice beds. Tritium concentrations were found to vary from 0.9 to 11 TU. This peak did not appear in the analyzed samples, providing an upper age limit of less than 50 years for the oldest sampled layer. It is suggested that the rate of melting is responsible for the absence of older firn layers. [ABSTRACT FROM AUTHOR]

Two of the most well-known caves of northern Greece, Petralona and Maaras, were morphometrically analyzed. They were strategically chosen for this morphometric study because they represent caves formed by different speleogenetic factors, resulting in patterns that clearly discriminate them from each other. Caves can display substantial variation in their patterns, depending on the local geology, hydrogeology, tectonics, and other factors. These qualitative parameters of speleogenesis, such as geological and hydrogeological controls, can be reflected in a cave's pattern. The different speleogenetic factors that create the patterns of the caves can be expressed in the mathematical indices, designating them as morphometrical tools for properly discriminating the two cave patterns. Petralona Cave falls into the category of a ramiform cave pattern. The cave's hypogenic origin is also supported by meso-scale cave morphology, and the hydrothermal activity of the surrounding area. On the other hand, Maaras Cave has a typical underground river pattern. The horizontal patterns of the two caves were morphometrically scrutinized using Euclidean and fractal geometry. [ABSTRACT FROM AUTHOR]

Firn from an ice cave in the highest mountain of Greece, Mt. Olympos, was sampled and analysed to determine the tritium content in order to estimate rates of accumulation and to date the ice plug. The presence of a sharp raise of tritium content because of the nuclear testing era was expected to be preserved into ice beds. This peak did not appear in the analysed samples providing an age estimation of less than 50 years. It is suggested that the rate of melting is responsible for the absence of older firn layers. [ABSTRACT FROM AUTHOR]