Search

Your search keyword '"Laurynas Bukelskis"' showing total 7 results
Start Over Author "Laurynas Bukelskis"
7 results on '"Laurynas Bukelskis"'

1. Results of the COVID-19 mental health international for the health professionals (COMET-HP) study: depression, suicidal tendencies and conspiracism

Author

Konstantinos N. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D. Alarcón, Kiyomi Arai, Sani Salihu Auwal, Julio Bobes, Teresa Bobes-Bascaran, Julie Bourgin-Duchesnay, Cristina Ana Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico de Berardis, Sergio Zamora Delgado, David de Lucena, Avinash de Sousa, Ramona di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J. Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K. Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian J. Garay, Leticia Garcia-Álvarez, Paz García-Portilla, Xenia Gonda, Tomasz M. Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, Tasdik M. Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jacobs, Miro Jakovljević, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Khalifa, Olena Khaustova, Steve Koh, Svetlana Kopishinskaia, Korneliia Kosenko, Sotirios A. Koupidis, Illes Kovacs, Barbara Kulig, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López, Petr Morozov, Nuru Suleiman Muhammad, Filip Mustač, Mika S. Naor, Amira Nassieb, Alvydas Navickas, Tarek Okasha, Milena Pandova, Anca-Livia Panfil, Liliya Panteleeva, Ion Papava, Mikaella E. Patsali, Alexey Pavlichenko, Bojana Pejuskovic, Mariana Pinto da Costa, Mikhail Popkov, Dina Popovic, Nor Jannah Nasution Raduan, Francisca Vargas Ramírez, Elmars Rancans, Salmi Razali, Federico Rebok, Anna Rewekant, Elena Ninoska Reyes Flores, María Teresa Rivera-Encinas, Pilar A. Saiz, Manuel Sánchez de Carmona, David Saucedo Martínez, Jo Anne Saw, Görkem Saygili, Patricia Schneidereit, Bhumika Shah, Tomohiro Shirasaka, Ketevan Silagadze, Satti Sitanggang, Oleg Skugarevsky, Anna Spikina, Sridevi Sira Mahalingappa, Maria Stoyanova, Anna Szczegielniak, Simona Claudia Tamasan, Giuseppe Tavormina, Maurilio Giuseppe Maria Tavormina, Pavlos N. Theodorakis, Mauricio Tohen, Eva-Maria Tsapakis, Dina Tukhvatullina, Irfan Ullah, Ratnaraj Vaidya, Johann M. Vega-Dienstmaier, Jelena Vrublevska, Olivera Vukovic, Olga Vysotska, Natalia Widiasih, Anna Yashikhina, Panagiotis E. Prezerakos, Michael Berk, Sarah Levaj, Daria Smirnova, Fountoulakis, Konstantinos N [0000-0001-5503-0811], N. Karakatsoulis, Grigorios [0000-0002-4786-1217], Castilla-Puentes, Ruby [0000-0002-0597-6155], Fountoulakis, Nikolaos K [0000-0002-5965-707X], Smirnova, Daria [0000-0002-9591-4918], and Apollo - University of Cambridge Repository

Subjects
Psychiatry, Health (social science), Social Psychology, Depression, Epidemiology, Conspiracy theories, COVID-19, Anxiety, Health professionals, Mental disorders, Mental health, Suicidality, Psychiatry and Mental health
Abstract

Introduction: The current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak. Materials and methods: The data came from the larger COMET-G study. The study sample includes 12,792 health professionals from 40 countries (62.40% women aged 39.76 ± 11.70; 36.81% men aged 35.91 ± 11.00 and 0.78% non-binary gender aged 35.15 ± 13.03). Distress and clinical depression were identified with the use of a previously developed cut-off and algorithm, respectively. Statistical analysis: Descriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses, and Factorial Analysis of Variance (ANOVA) tested relations among variables. Results: Clinical depression was detected in 13.16% with male doctors and ‘non-binary genders’ having the lowest rates (7.89 and 5.88% respectively) and ‘non-binary gender’ nurses and administrative staff had the highest (37.50%); distress was present in 15.19%. A significant percentage reported a deterioration in mental state, family dynamics, and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (24.64% vs. 9.62%; p < 0.0001). Suicidal tendencies were at least doubled in terms of RASS scores. Approximately one-third of participants were accepting (at least to a moderate degree) a non-bizarre conspiracy. The highest Relative Risk (RR) to develop clinical depression was associated with a history of Bipolar disorder (RR = 4.23). Conclusions: The current study reported findings in health care professionals similar in magnitude and quality to those reported earlier in the general population although rates of clinical depression, suicidal tendencies, and adherence to conspiracy theories were much lower. However, the general model of factors interplay seems to be the same and this could be of practical utility since many of these factors are modifiable. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

Published
2023

2. The effect of different degrees of lockdown and self-identified gender on anxiety, depression and suicidality during the COVID-19 pandemic: Data from the international COMET-G study

Author

Konstantinos N. Fountoulakis, Grigorios N. Karakatsoulis, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D. Alarcón, Kiyomi Arai, Sani Salihu Auwal, Michael Berk, Sarah Bjedov, Julio Bobes, Teresa Bobes-Bascaran, Julie Bourgin-Duchesnay, Cristina Ana Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico De Berardis, Sergio Zamora Delgado, David De Lucena, Avinash De Sousa, Ramona Di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J. Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K. Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian J. Garay, Leticia Garcia-Álvarez, Maria Paz García-Portilla, Xenia Gonda, Tomasz M. Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, Tasdik M. Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jacobs, Miro Jakovljević, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Khalifa, Olena Khaustova, Steve Koh, Svetlana Kopishinskaia, Korneliia Kosenko, Sotirios A. Koupidis, Illes Kovacs, Barbara Kulig, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López, Petr Morozov, Nuru Suleiman Muhammad, Filip Mustač, Mika S. Naor, Amira Nassieb, Alvydas Navickas, Tarek Okasha, Milena Pandova, Anca-Livia Panfil, Liliya Panteleeva, Ion Papava, Mikaella E. Patsali, Alexey Pavlichenko, Bojana Pejuskovic, Mariana Pinto Da Costa, Mikhail Popkov, Dina Popovic, Nor Jannah Nasution Raduan, Francisca Vargas Ramírez, Elmars Rancans, Salmi Razali, Federico Rebok, Anna Rewekant, Elena Ninoska Reyes Flores, María Teresa Rivera-Encinas, Pilar Saiz, Manuel Sánchez de Carmona, David Saucedo Martínez, Jo Anne Saw, Görkem Saygili, Patricia Schneidereit, Bhumika Shah, Tomohiro Shirasaka, Ketevan Silagadze, Satti Sitanggang, Oleg Skugarevsky, Anna Spikina, Sridevi Sira Mahalingappa, Maria Stoyanova, Anna Szczegielniak, Simona Claudia Tamasan, Giuseppe Tavormina, Maurilio Giuseppe Maria Tavormina, Pavlos N. Theodorakis, Mauricio Tohen, Eva Maria Tsapakis, Dina Tukhvatullina, Irfan Ullah, Ratnaraj Vaidya, Johann M. Vega-Dienstmaier, Jelena Vrublevska, Olivera Vukovic, Olga Vysotska, Natalia Widiasih, Anna Yashikhina, Panagiotis E. Prezerakos, Daria Smirnova, Karakatsoulis, Grigorios N [0000-0002-4786-1217], Alarcón, Renato D [0000-0002-7316-1185], Berk, Michael [0000-0002-5554-6946], Apollo - University of Cambridge Repository, Psychiatry 1, RS: MHeNs - R2 - Mental Health, and Psychiatrie & Neuropsychologie

Subjects
Male, Mental health, lockdown, anxiety, mental health history, Depression, Depression/epidemiology, COVID-19, Suicidality, Anxiety, Psychiatry and Mental health, Suicide, Communicable Disease Control, Humans, Female, Pandemics, Biological Psychiatry, Anxiety/epidemiology
Abstract

Fountoulakis K.N., Karakatsoulis G.N., Abraham S., Adorjan K., Ahmed H.U., Alarcón R.D., Arai K., Auwal S.S., Berk M., Bjedov S., Bobes J., Bobes-Bascaran T., Bourgin-Duchesnay J., Bredicean C.A., Bukelskis L., Burkadze A., Abud I.I.C., Castilla-Puentes R., Cetkovich M., Colon-Rivera H., Corral R., Cortez-Vergara C., Crepin P., De Berardis D., Delgado S.Z., De Lucena D., De Sousa A., Stefano R.D., Dodd S., Elek L.P., Elissa A., Erdelyi-Hamza B., Erzin G., Etchevers M.J., Falkai P., Farcas A., Fedotov I., Filatova V., Fountoulakis N.K., Frankova I., Franza F., Frias P., Galako T., Garay C.J., Garcia-Álvarez L., García-Portilla M.P., Gonda X., Gondek T.M., González D.M., Gould H., Grandinetti P., Grau A., Groudeva V., Hagin M., Harada T., Hasan T.M., Hashim N.A., Hilbig J., Hossain S., Iakimova R., Ibrahim M., Iftene F., Ignatenko Y., Irarrazaval M., Ismail Z., Ismayilova J., Jacobs A., Jakovljević M., Jakšić N., Javed A., Kafali H.Y., Karia S., Kazakova O., Khalifa D., Khaustova O., Koh S., Kopishinskaia S., Kosenko K., Koupidis S.A., Kovacs I., Kulig B., Lalljee A., Liewig J., Majid A., Malashonkova E., Malik K., Malik N.I., Mammadzada G., Mandalia B., Marazziti D., Marčinko D., Martinez S., Matiekus E., Mejia G., Memon R.S., Martínez X.E.M., Mickevičiūtė D., Milev R., Mohammed M., Molina-López A., Morozov P., Muhammad N.S., Mustač F., Naor M.S., Nassieb A., Navickas A., Okasha T., Pandova M., Panfil A.-L., Panteleeva L., Papava I., Patsali M.E., Pavlichenko A., Pejuskovic B., Da Costa M.P., Popkov M., Popovic D., Raduan N.J.N., Ramírez F.V., Rancans E., Razali S., Rebok F., Rewekant A., Flores E.N.R., Rivera-Encinas M.T., Saiz P., de Carmona M.S., Martínez D.S., Saw J.A., Saygili G., Schneidereit P., Shah B., Shirasaka T., Silagadze K., Sitanggang S., Skugarevsky O., Spikina A., Mahalingappa S.S., Stoyanova M., Szczegielniak A., Tamasan S.C., Tavormina G., Tavormina M.G.M., Theodorakis P.N., Tohen M., Tsapakis E.M., Tukhvatullina D., Ullah I., Vaidya R., Vega-Dienstmaier J.M., Vrublevska J., Vukovic O., Vysotska O., Widiasih N., Yashikhina A., Prezerakos P.E., Smirnova D.

Published
2022
Full Text
View/download PDF

3. Gender, age at onset, and duration of being ill as predictors for the long-term course and outcome of schizophrenia : an international multicenter study

Author

Nikolaos Smyrnis, Felicia Iftene, Olivera Vuković, Henry K. Karlsson, Jan Hilbig, Dan J. Stein, Marc De Hert, C. Bredicean, Ion Papava, Sanja Vodopic, Jean-Michel Azorin, Athanasios Douzenis, Maija Walta, Hasan Karadağ, Petra Furstova, Filip Spaniel, Klaudia Domowicz, Anuja Bendre, María Paz García-Portilla, Gamze Erzin, Erik Thys, Valentina Corigliano, Paweł Wójciak, Anastasia Konsta, Amresh Shrivastava, Anca-Livia Panfil, Dora Vajda, Elmars Rancans, Martien Wampers, Lidija Injac Stevovic, Leticia García-Álvarez, Anita Juhasz, Oluremi Oladele, Xenofon Atmatzidis, Alvydas Navickas, Ioannis Michopoulos, Pavel Knytl, Ida S. Haussleiter, Trayana Hristova, Rajiv Tandon, Dusica Lecic-Tosevski, Maria Luísa Figueira, Fleur M. Howells, Laurynas Bukelskis, Daria Smirnova, Leonidas Mantonakis, Olga Izmailova, Joana Crawford, Justine Bouniard, Panagiotis Ferentinos, Vincent Russell, Oluyomi Esan, Julie Montant, Tobias Wiklund, Tiina From, Luchezar Hranov, Roumen Milev, Georg Juckel, Nikolaos K. Fountoulakis, Michael Berk, Janusz K. Rybakowski, Ioannis Nimatoudis, Elena Dragioti, Cyril Höschl, Julio Bobes, Zsófia Nemes, Anna Comparelli, Bojana Pejuskovic, Olivia M Dean, Konstantinos N. Fountoulakis, Avinash De Sousa, Loukas Athanasiadis, Daniil Aptalidis, Ludgero Linhares, Henk Temmingh, Raimo K. R. Salokangas, Antonis T. Theofilidis, John L. Waddington, Xenia Gonda, Christopher Osunbote, Siegfried Kasper, and Maurizio Pompili

Subjects
Male, Pediatrics, medicine.medical_specialty, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Age of Onset, Depression (differential diagnoses), Positive and Negative Syndrome Scale, business.industry, Confounding, medicine.disease, Mental health, 030227 psychiatry, 3. Good health, Diagnostic and Statistical Manual of Mental Disorders, Psychiatry and Mental health, Schizophrenia, Anxiety, Female, Neurology (clinical), Analysis of variance, Human medicine, medicine.symptom, business, 030217 neurology & neurosurgery, Diagnosis of schizophrenia
Abstract

BackgroundThe aim of the current study was to explore the effect of gender, age at onset, and duration on the long-term course of schizophrenia.MethodsTwenty-nine centers from 25 countries representing all continents participated in the study that included 2358 patients aged 37.21 ± 11.87 years with a DSM-IV or DSM-5 diagnosis of schizophrenia; the Positive and Negative Syndrome Scale as well as relevant clinicodemographic data were gathered. Analysis of variance and analysis of covariance were used, and the methodology corrected for the presence of potentially confounding effects.ResultsThere was a 3-year later age at onset for females (P P P P = .001). No significant effects were found concerning duration of illness.DiscussionOur results confirmed a later onset and a possibly more benign course and outcome in females. Age at onset manifested a single peak in both genders, and surprisingly, earlier onset was related to a slower progression of the illness. No effect of duration has been detected. These results are partially in accord with the literature, but they also differ as a consequence of the different starting point of our methodology (a novel staging model), which in our opinion precluded the impact of confounding effects. Future research should focus on the therapeutic policy and implications of these results in more representative samples.

Published
2022

4. Results of the COVID-19 mental health international for the general population (COMET-G) study

Author

Kiyomi Arai, Anca Livia Panfil, Darko Marčinko, J. Vrublevska, Muftau Mohammed, Dalia Mickevičiūtė, Piirika Crepin, Görkem Saygili, Nor Jannah Nasution Raduan, Seetal Dodd, Anna Yashikhina, Daniela Morera González, Elmars Rancans, Cristian Javier Garay, Helal Uddin Ahmed, Khamelia Malik, Eimantas Matiekus, Tomohiro Shirasaka, Paolo Grandinetti, Tasdik M. Hasan, Sotirios A. Koupidis, Nurul Azreen Hashim, Pilar A. Saiz, David Saucedo Martínez, Arturo Grau, Alejandro Molina-López, Jo Anne Saw, Dina Tukhvatullina, Felicia Iftene, Renato D. Alarcón, Svetlana Kopishinskaia, Sahadat Hossain, Olivera Vuković, Mika S. Naor, Satti Sitanggang, Sridevi Sira Mahalingappa, Leticia García-Álvarez, Manuel Sanchez de Carmona, Liliya Panteleeva, Olga Kazakova, Jan Hilbig, Johann M. Vega-Dienstmaier, Francesco Franza, Matias Irarrazaval, Pavlos N. Theodorakis, Sani Salihu Auwal, Alvydas Navickas, Domenico De Berardis, Viktoriia Filatova, David Freitas de Lucena, Miro Jakovljevic, Afzal Javed, Gulay Mammadzada, Olena Khaustova, Adriana Farcas, Steve Koh, Ruby C. Castilla-Puentes, Panagiotis E. Prezerakos, Gamze Erzin, Takayuki Harada, Pedro Frias, Tatiana Galako, Kristina Adorjan, Hector Colon-Rivera, Justine Liewig, Oleg Skugarevsky, Indira Indiana Cabrera Abud, Sarah Bjedov, Berta Erdelyi-Hamza, Korneliia Kosenko, Barbara Kulig, Xarah Elenne Meza Martínez, Bojana Pejuskovic, Ratnaraj Vaidya, Elena Ninoska Reyes Flores, Sergio Zamora Delgado, Marcelo Cetkovich, Avinash De Sousa, Eva Maria Tsapakis, Iryna Frankova, Federico Rebok, Petr Morozov, Amira Nassieb, Bilvesh Mandalia, Alexey Pavlichenko, Mariana Pinto da Costa, Anna Rewekant, Patricia Schneidereit, Olga Vysotska, Roumen Milev, Maria Stoyanova, Laurynas Bukelskis, Roha Saeed Memon, Ricardo Corral, Nuru Suleiman Muhammad, Donatella Marazziti, Michal Hagin, María Teresa Rivera-Encinas, Julie Bourgin-Duchesnay, Giuseppe Tavormina, Jamila Ismayilova, Mauricio Tohen, Helin Yilmaz Kafali, María Paz García-Portilla, Violeta Groudeva, Daria Smirnova, Mikaella E. Patsali, Ramona Di Stefano, Filip Mustač, Nikolaos K. Fountoulakis, Dina Popovic, Abdul Majid, Michael Berk, Anna Spikina, Alisha Lalljee, Zaliha Ismail, Mikhail Popkov, Xenia Gonda, Julio Bobes, Sagar Karia, Salmi Razali, Carla Cortez-Vergara, Konstantinos N. Fountoulakis, Rossitza Iakimova, Francisca Vargas Ramírez, Maurilio Giuseppe Maria Tavormina, Asaf Jakobs, Najma Iqbal Malik, Teresa Bobes-Bascarán, Illés Kovács, Hilary Gould, Tarek Okasha, Anna Szczegielniak, Peter Falkai, Nenad Jakšić, Livia Priyanka Elek, Evgeniia Malashonkova, C. Bredicean, Yulia Ignatenko, Bhumika Shah, Akaki Burkadze, Seri Abraham, Anna Elissa, Ion Papava, Mona Ibrahim, Doaa Ahmed Khalifa, Milena Pandova, Gabriela Mejia, Tomasz M. Gondek, Simona Claudia Tamasan, Grigorios N Karakatsoulis, Ketevan Silagadze, Stephanie Martinez, Ilya Fedotov, Martin J. Etchevers, Irfan Ullah, Natalia Widiasih, Berk, Michael [0000-0002-5554-6946], Bobes-Bascaran, Teresa [0000-0002-5279-504X], and Apollo - University of Cambridge Repository

Subjects
Male, Psychological intervention, Anxiety, Mental disorders, Suicidality, Global Burden of Disease, COVID-19 / epidemiology, 0302 clinical medicine, Anxiety / epidemiology, COVID-19, depression, suicidality, mental health, conspiracy theories, mental disorders, psychiatry, anxiety, Pharmacology (medical), 030212 general & internal medicine, Depression (differential diagnoses), Psychiatry, education.field_of_study, Depression, Anxiety / etiology, Conspiracy theories, Mental Health, Middle Aged, Depression / etiology, 3. Good health, Psychiatry and Mental health, Distress, COVID-19 / complications, Neurology, Female, Mental health, medicine.symptom, Clinical psychology, Adult, COVID-19 / psychology, Population, Article, Suicidal Ideation, 03 medical and health sciences, medicine, Humans, Bipolar disorder, education, Pandemics, Biological Psychiatry, Depression / epidemiology, Pharmacology, business.industry, SARS-CoV-2, Stress, Psychological / etiology, medicine.disease, Relative risk, Neurology (clinical), business, 030217 neurology & neurosurgery, Stress, Psychological
Abstract

Introduction: There are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study. ----- Material and methods: During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and 1.10% other aged 31.64±13.15). Distress and probable depression were identified with the use of a previously developed cut-off and algorithm respectively. ----- Statistical analysis: Descriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses and Factorial Analysis of Variance (ANOVA) tested relations among variables. ----- Results: Probable depression was detected in 17.80% and distress in 16.71%. A significant percentage reported a deterioration in mental state, family dynamics and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (31.82% vs. 13.07%). At least half of participants were accepting (at least to a moderate degree) a non-bizarre conspiracy. The highest Relative Risk (RR) to develop depression was associated with history of Bipolar disorder and self-harm/attempts (RR = 5.88). Suicidality was not increased in persons without a history of any mental disorder. Based on these results a model was developed. ----- Conclusions: The final model revealed multiple vulnerabilities and an interplay leading from simple anxiety to probable depression and suicidality through distress. This could be of practical utility since many of these factors are modifiable. Future research and interventions should specifically focus on them.

Published
2021

5. Modeling psychological function in patients with schizophrenia with the PANSS: an international multi-center study

Author

Jean-Michel Azorin, Martien Wampers, Leonidas Mantonakis, Hasan Karadağ, Daniil Aptalidis, Xenofon Atmatzidis, Anuja Bendre, Loukas Athanasiadis, Anita Juhasz, Gamze Erzin, Dan J. Stein, Zsófia Nemes, Paweł Wójciak, Ioannis Michopoulos, Antonis T. Theofilidis, Marc De Hert, Panagiotis Ferentinos, Trayana Hristova, C. Bredicean, Maija Walta, Ludgero Linhares, Ion Papava, Athanasios Douzenis, Christopher Osunbote, Sanja Vodopic, Vincent Russell, Olivia M Dean, Maurizio Pompili, Rajiv Tandon, Anastasia Konsta, Ioannis Nimatoudis, Nikolaos Smyrnis, Cyril Höschl, Anna Comparelli, Konstantinos N. Fountoulakis, Anca-Livia Panfil, Julie Montant, Dora Vajda, Erik Thys, Valentina Corigliano, Julio Bobes, Felicia Iftene, Tobias Wiklund, Elena Dragioti, Daria Smirnova, Klaudia Domowicz, Olivera Vuković, Jan Hilbig, Luchezar Hranov, Amresh Shrivastava, Tiina From, John L. Waddington, Ida S. Haussleiter, Avinash De Sousa, María Paz García-Portilla, Georg Juckel, Oluyomi Esan, Elmars Rancans, Xenia Gonda, Siegfried Kasper, Bojana Pejuskovic, Fleur M. Howells, Henk Temmingh, Raimo K. R. Salokangas, Leticia García-Álvarez, Oluremi Oladele, Alvydas Navickas, Roumen Milev, Olga Izmailova, Joana Crawford, Justine Bouniard, Michael Berk, Janusz K. Rybakowski, Dusica Lecic-Tosevski, Lidija Injac Stevovic, Henry K. Karlsson, Petra Furstova, Filip Spaniel, Maria Luísa Figueira, Laurynas Bukelskis, and Pavel Knytl

Subjects
Adult, Male, Adolescent, Hostility, Disease, 03 medical and health sciences, 0302 clinical medicine, long-term course, model, outcome, schizophrenia, staging, medicine, Humans, In patient, Depression (differential diagnoses), Aged, Aged, 80 and over, Positive and Negative Syndrome Scale, Middle Aged, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Schizophrenia, Disease Progression, Anxiety, Female, Schizophrenic Psychology, Human medicine, Neurology (clinical), medicine.symptom, Psychology, Neurocognitive, 030217 neurology & neurosurgery, Clinical psychology
Abstract

BackgroundThe aim of the current study was to explore the changing interrelationships among clinical variables through the stages of schizophrenia in order to assemble a comprehensive and meaningful disease model.MethodsTwenty-nine centers from 25 countries participated and included 2358 patients aged 37.21 ± 11.87 years with schizophrenia. Multiple linear regression analysis and visual inspection of plots were performed.ResultsThe results suggest that with progression stages, there are changing correlations among Positive and Negative Syndrome Scale factors at each stage and each factor correlates with all the others in that particular stage, in which this factor is dominant. This internal structure further supports the validity of an already proposed four stages model, with positive symptoms dominating the first stage, excitement/hostility the second, depression the third, and neurocognitive decline the last stage.ConclusionsThe current study investigated the mental organization and functioning in patients with schizophrenia in relation to different stages of illness progression. It revealed two distinct “cores” of schizophrenia, the “Positive” and the “Negative,” while neurocognitive decline escalates during the later stages. Future research should focus on the therapeutic implications of such a model. Stopping the progress of the illness could demand to stop the succession of stages. This could be achieved not only by both halting the triggering effect of positive and negative symptoms, but also by stopping the sensitization effect on the neural pathways responsible for the development of hostility, excitement, anxiety, and depression as well as the deleterious effect on neural networks responsible for neurocognition.

Published
2020

6. Staging of Schizophrenia with the Use of PANSS: An International Multi-Center Study

Author

Olga Izmailova, Joana Crawford, Justine Bouniard, Athanasios Douzenis, Zsófia Nemes, Erik Thys, Valentina Corigliano, Roumen Milev, Michael Berk, Tiina From, Dan J. Stein, Fleur M. Howells, Georg Juckel, Marc De Hert, C. Bredicean, Daniil Aptalidis, Hasan Karadağ, Anuja Bendre, Trayana Hristova, Dora Vajda, Tobias Wikilund, Maija Walta, Nikolaos Smyrnis, Luchezar Hranov, Antonis T. Theofilidis, Daria Smirnova, Oluyomi Esan, Felicia Iftene, Olivia M Dean, Olivera Vuković, Jan Hilbig, Klaudia Domowicz, Vincent Russell, Xenofon Atmatzidis, Konstantinos N. Fountoulakis, Julie Montant, Anita Juhasz, Ida S. Haussleiter, Maria Luísa Figueira, Janusz Κ Rybakowski, Leticia García-Álvarez, Ioannis Nimatoudis, Ion Papava, Ioannis Michopoulos, Sanja Vodopic, Oluremi Oladele, Alvydas Navickas, Christopher Osunbote, Anastasia Konsta, Rajiv Tandon, Jean-Michel Azorin, Avinash De Sousa, Henry K. Karlsson, Laurynas Bukelskis, Loukas Athanasiadis, Maurizio Pompili, Leonidas Mantonakis, Petra Furstova, Elena Dragioti, John L. Waddington, Filip Spaniel, Martien Wampers, Ludgero Linhares, Anca-Livia Panfil, Dusica Lecic-Tosevski, Xenia Gonda, Siegfried Kasper, Panagiotis Ferentinos, Henk Temmingh, Lidija Injac Stevovic, Raimo K. R. Salokangas, Pavel Knytl, Amresh Shrivastava, Elmars Rancans, Gamze Erzin, Paweł Wójciak, Cyril Höschl, Julio Bobes, Anna Comparelli, María Paz García-Portilla, and Bojana Pejuskovic

Subjects
Adult, Male, Paranoid schizophrenia, Nigeria, Hostility, Regular Research Articles, Psykiatri, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Discriminant function analysis, medicine, Humans, Pharmacology (medical), Psychiatric Status Rating Scales, Psychiatry, Pharmacology, Sotos Syndrome, Positive and Negative Syndrome Scale, business.industry, illness course, outcome, schizophrenia, staging, Middle Aged, medicine.disease, Exploratory factor analysis, Confirmatory factor analysis, 3. Good health, 030227 psychiatry, Europe, Editor's Choice, Psychiatry and Mental health, Schizophrenia, Disease Progression, Anxiety, Female, medicine.symptom, Factor Analysis, Statistical, business, 030217 neurology & neurosurgery, Clinical psychology
Abstract

M.B. is supported by a NHMRC Senior Principal Research Fellowship (APP1059660 and APP1156072). All authors contributed equally., Fountoulakis, K.N., Dragioti, E., Theofilidis, A.T., Wikilund, T., Atmatzidis, X., Nimatoudis, I., Thys, E., Wampers, M., Hranov, L., Hristova, T., Aptalidis, D., Milev, R., Iftene, F., Spaniel, F., Knytl, P., Furstova, P., From, T., Karlsson, H., Walta, M., Salokangas, R.K.R., Azorin, J.-M., Bouniard, J., Montant, J., Juckel, G., Haussleiter, I.S., Douzenis, A., Michopoulos, I., Ferentinos, P., Smyrnis, N., Mantonakis, L., Nemes, Z., Gonda, X., Vajda, D., Juhasz, A., Shrivastava, A., Waddington, J., Pompili, M., Comparelli, A., Corigliano, V., Rancans, E., Navickas, A., Hilbig, J., Bukelskis, L., Injac Stevovic, L., Vodopic, S., Esan, O., Oladele, O., Osunbote, C., Rybakowski, J.Κ., Wojciak, P., Domowicz, K., Figueira, M.L., Linhares, L., Crawford, J., Panfil, A.-L., Smirnova, D., Izmailova, O., Lecic-Tosevski, D., Temmingh, H., Howells, F., Bobes, J., Garcia-Portilla, M.P., García-Alvarez, L., Erzin, G., Karadaǧ, H., De Sousa, A., Bendre, A., Hoschl, C., Bredicean, C., Papava, I., Vukovic, O., Pejuskovic, B., Russell, V., Athanasiadis, L., Konsta, A., Stein, D., Berk, M., Dean, O., Tandon, R., Kasper, S., De Hert, M.

Published
2019

7. Antipsichotikų vaidmuo ir jo pagrindimas gydant nervinę anoreksiją

Author

Laurynas Bukelskis and Brigita Baks

Subjects
Olanzapine, medicine.medical_specialty, Psychotherapist, Forensic psychiatry, mental disorders, medicine, Cognition, Disease, Psychiatry, Psychology, Body mass index, medicine.drug
Abstract

While the neurobiology of anorexia nervosa becomes clearer, specific treatment has not been established yet. A lot was expected from atypical antipsychotics, especially olanzapine among them. Although the neurobiology of the disease and the mechanism of these drugs suite each other, the clear benefit has not been determined. It seems that body mass index and the cognition of the disease are not significantly affected, although depression might be improved. The presentation delivered during the 8th international conference of forensic psychiatry „Reflection of reality – norm and pathology“ was aimed to review the literature about the basis and efficacy of atypical antipsychotics in the treatment of anorexia nervosa.

Published
2014

Catalog

Books, media, physical & digital resources
See catalog results