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313 results on '"Laughlin-Tommaso, Shannon K"'

1. Detection of endometrial cancer using tampon-based collection and methylated DNA markers

Author

Bakkum-Gamez, Jamie N., Sherman, Mark E., Slettedahl, Seth W., Mahoney, Douglas W., Lemens, Maureen A., Laughlin-Tommaso, Shannon K., Hopkins, Matthew R., VanOosten, Ann, Shridhar, Viji, Staub, Julie K., Cao, Xiaoming, Foote, Patrick H., Clarke, Megan A., Burger, Kelli N., Berger, Calise K., O'Connell, Maria C., Doering, Karen A., Podratz, Karl C., DeStephano, Christopher C., Schoolmeester, J. Kenneth, Kerr, Sarah E., Wentzensen, Nicolas, Taylor, William R., and Kisiel, John B.

Published
2023
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3. Genital Fistulas

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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5. Ovarian Tumors

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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11. Infertility

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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13. Menopause

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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14. Urodynamic Study

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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16. Contraception

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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20. Basic Gynecology

Author

Shazly, Sherif, Laughlin-Tommaso, Shannon K., Shazly, Sherif, and Laughlin-Tommaso, Shannon K.

Published
2020
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26. Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis.

Author

Barnard, Emily P, AbdElmagied, Ahmed M, Vaughan, Lisa E, Weaver, Amy L, Laughlin-Tommaso, Shannon K, Hesley, Gina K, Woodrum, David A, Jacoby, Vanessa L, Kohi, Maureen P, Price, Thomas M, Nieves, Angel, Miller, Michael J, Borah, Bijan J, Gorny, Krzysztof R, Leppert, Phyllis C, Peterson, Lisa G, and Stewart, Elizabeth A

Subjects
Humans, Leiomyoma, Uterine Neoplasms, Pain, Postoperative, Analgesics, Opioid, Antiemetics, Anti-Inflammatory Agents, Non-Steroidal, Cohort Studies, Recovery of Function, Adult, Drug Utilization, Female, Magnetic Resonance Imaging, Interventional, Uterine Artery Embolization, Ultrasonic Surgical Procedures, Return to Work, Visual Analog Scale, focused ultrasound, leiomyoma, randomized controlled trial, uterine artery embolization, uterine fibroid, Contraception/Reproduction, Clinical Research, Fibroid Tumors (Uterine), Pain Research, Clinical Trials and Supportive Activities, Patient Safety, Chronic Pain, Reproductive health and childbirth, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine
Abstract

BackgroundUterine fibroids are a common problem for reproductive-aged women, yet little comparative effectiveness research is available to guide treatment choice. Uterine artery embolization and magnetic resonance imaging-guided focused ultrasound surgery are minimally invasive therapies approved by the US Food and Drug Administration for treating symptomatic uterine fibroids. The Fibroid Interventions: Reducing Symptoms Today and Tomorrow study is the first randomized controlled trial to compare these 2 fibroid treatments.ObjectiveThe objective of the study was to summarize treatment parameters and compare recovery trajectory and adverse events in the first 6 weeks after treatment.Study designPremenopausal women with symptomatic uterine fibroids seen at 3 US academic medical centers were enrolled in the randomized controlled trial (n = 57). Women meeting identical criteria who declined randomization but agreed to study participation were enrolled in a nonrandomized parallel cohort (n = 34). The 2 treatment groups were analyzed by using a comprehensive cohort design. All women undergoing focused ultrasound and uterine artery embolization received the same postprocedure prescriptions, instructions, and symptom diaries for comparison of recovery in the first 6 weeks. Return to work and normal activities, medication use, symptoms, and adverse events were captured with postprocedure diaries. Data were analyzed using the Wilcoxon rank sum test or χ2 test. Multivariable regression was used to adjust for baseline pain levels and fibroid load when comparing opioid medication, adverse events, and recovery time between treatment groups because these factors varied at baseline between groups and could affect outcomes. Adverse events were also collected.ResultsOf 83 women in the comprehensive cohort design who underwent treatment, 75 completed postprocedure diaries. Focused ultrasound surgery was a longer procedure than embolization (mean [SD], 405 [146] vs 139 [44] min; P

Published
2017

27. Comparative effectiveness of hysterectomy versus myomectomy on one-year health-related quality of life in women with uterine fibroids

Author

Wallace, Kedra, Zhang, Shuaiqi, Thomas, Laine, Stewart, Elizabeth A., Nicholson, Wanda Kay, Wegienka, Ganesa R., Wise, Lauren A., Laughlin-Tommaso, Shannon K., Diamond, Michael P., Marsh, Erica E., Jacoby, Vanessa L., Anchan, Raymond M., Venable, Sateria, Larry, G. Maxwell, Lytle, Barbara, Wang, Tracy, and Myers, Evan R.

Published
2020
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29. Fibroid interventions: reducing symptoms today and tomorrow: extending generalizability by using a comprehensive cohort design with a randomized controlled trial.

Author

AbdElmagied, Ahmed M, Vaughan, Lisa E, Weaver, Amy L, Laughlin-Tommaso, Shannon K, Hesley, Gina K, Woodrum, David A, Jacoby, Vanessa L, Kohi, Maureen P, Price, Thomas M, Nieves, Angel, Miller, Michael J, Borah, Bijan J, Gorny, Krzysztof R, Leppert, Phyllis C, Lemens, Maureen A, and Stewart, Elizabeth A

Subjects
Humans, Leiomyoma, Uterine Neoplasms, Pain Measurement, Body Mass Index, Ultrasonic Therapy, Cohort Studies, Smoking, Gravidity, Adult, Female, Uterine Artery Embolization, focused ultrasound, leiomyomas, study design, uterine artery embolization, uterine fibroids, Clinical Trials and Supportive Activities, Chronic Pain, Cancer, Fibroid Tumors (Uterine), Biomedical Imaging, Clinical Research, Pain Research, Comparative Effectiveness Research, Prevention, Contraception/Reproduction, Cost Effectiveness Research, Reproductive health and childbirth, Good Health and Well Being, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine
Abstract

BackgroundUterine fibroids are an important source of morbidity for reproductive-aged women. Despite an increasing number of alternatives, hysterectomies account for about 75% of all fibroid interventional treatments. Evidence is lacking to help women and their health care providers decide among alternatives to hysterectomy. Fibroid Interventions: Reducing Symptoms Today and Tomorrow (NCT00995878, clinicaltrials.gov) is a randomized controlled trial to compare the safety, efficacy, and economics of 2 minimally invasive alternatives to hysterectomy: uterine artery embolization and magnetic resonance imaging-guided focused ultrasound surgery. Although randomized trials provide the highest level of evidence, they have been difficult to conduct in the United States for interventional fibroid treatments. Thus, contemporaneously recruiting women declining randomization may have value as an alternative strategy for comparative effectiveness research.ObjectiveWe sought to compare baseline characteristics of randomized participants with nonrandomized participants meeting the same enrollment criteria and to determine whether combining the 2 cohorts in a comprehensive cohort design would be useful for analysis.Study designPremenopausal women with symptomatic uterine fibroids seeking interventional therapy at 3 US academic medical centers were randomized (1:1) in 2 strata based on calculated uterine volume (

Published
2016

32. Gynecology

Author

Shazly, Sherif, primary and Laughlin-Tommaso, Shannon K., additional

Published
2020
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48. In Reply

Author

Laughlin-Tommaso, Shannon K., Smith, Carin Y., Weaver, Amy L., Khan, Zaraq, Stewart, Elizabeth A., and Rocca, Walter A.

Published
2019
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