2,114 results on '"Lauffenburger, Douglas A."'
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2. Recovering biomolecular network dynamics from single-cell omics data requires three time points
3. Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination
4. Impact of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV
5. Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity
6. Landscape of Human Immunodeficiency Virus Neutralization Susceptibilities Across Tissue Reservoirs
7. Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype
8. ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19
9. Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection.
10. Inference of drug off-target effects on cellular signaling using interactome-based deep learning
11. Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination
12. Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design
13. Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains
14. Placental transfer dynamics and durability of maternal COVID-19 vaccine-induced antibodies in infants
15. Borrelia-specific antibody profiles and complement deposition in joint fluid distinguish antibiotic-refractory from -responsive Lyme arthritis
16. Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in macaques primed with distinct vaccines
17. Mining for humoral correlates of HIV control and latent reservoir size.
18. Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
19. Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines
20. Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates
21. Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains
22. Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis
23. Systematic deconstruction of myeloid cell signaling in tuberculosis granulomas reveals IFN-γ, TGF-β, and time are associated with conserved myeloid diversity
24. Cross species modeling reveals a role for the unfolded protein response in shaping the transcriptional reaction to Mycobacterium tuberculosis infection
25. Markov Field network integration of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques
26. Pooled screening for CAR function identifies novel IL13Rα2-targeted CARs for treatment of glioblastoma
27. Nucleocapsid-specific antibody function is associated with therapeutic benefits from COVID-19 convalescent plasma therapy
28. Systems Modeling Identifies Divergent Receptor Tyrosine Kinase Reprogramming to MAPK Pathway Inhibition
29. Towards targeting of shared mechanisms of cancer metastasis and therapy resistance
30. Artificial neural networks enable genome-scale simulations of intracellular signaling
31. Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse
32. Selective transfer of maternal antibodies in preterm and fullterm children
33. Endometrial cytokines in patients with and without endometriosis evaluated for infertility
34. New biological solutions to the many problems of our time.
35. Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement
36. Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors
37. Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding
38. Apoptotic Bodies Elicit Gas6-Mediated Migration of AXL-Expressing Tumor Cells
39. Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
40. Reduced antibody activity against SARS-CoV-2 B.1.617.2 delta virus in serum of mRNA-vaccinated individuals receiving tumor necrosis factor-α inhibitors
41. Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection
42. Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies
43. Selective functional antibody transfer into the breastmilk after SARS-CoV-2 infection
44. 665 Widespread maternal immunity to RSV suggests naturally-occurring antibodies provide incomplete neonatal protection: implications for vaccination
45. 108 Unique maternal immunoproteomic signatures by trimester and in response to de novo mRNA vaccination
46. Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M vaccination
47. Cell–cell communication networks in tissue: Toward quantitatively linking structure with function
48. Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer
49. Quantitative phosphoproteomics uncovers dysregulated kinase networks in Alzheimer’s disease
50. Humoral signatures of protective and pathological SARS-CoV-2 infection in children
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