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1,553 results on '"Laufer, G."'

4. HeartMate 3 Snoopy: Non-invasive cardiovascular diagnosis of patients with fully magnetically levitated blood pumps during echocardiographic speed ramp tests and Valsalva maneuvers

Author

Schlöglhofer, T., primary, Gross, C., additional, Abart, T., additional, Schaefer, AK., additional, Marko, C., additional, Röhrich, M., additional, Widhalm, G., additional, Kaufmann, F., additional, Weigel, I., additional, Al Asadi, H., additional, Karner, B., additional, Riebandt, J., additional, Wiedemann, D., additional, Laufer, G., additional, Schima, H., additional, and Zimpfer, D., additional

Published
2023
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5. Beating Versus Arrested Heart Isolated Tricuspid Valve Surgery: Long-term Outcomes

Author

Russo, M, Di Mauro, M, Saitto, G, Lio, A, Berretta, P, Taramasso, M, Scrofani, R, Della Corte, A, Sponga, S, Greco, E, Saccocci, M, Calafiore, A, Bianchi, G, Leviner, D, Biondi, A, Della Ratta, E, Livi, U, Sharoni, E, Werner, P, De Vincentiis, C, Di Eusanio, M, Kocher, A, Antona, C, Miraldi, F, Troise, G, Solinas, M, Maisano, F, Laufer, G, Musumeci, F, Andreas, M, Russo M., Di Mauro M., Saitto G., Lio A., Berretta P., Taramasso M., Scrofani R., Della Corte A., Sponga S., Greco E., Saccocci M., Calafiore A., Bianchi G., Leviner D. B., Biondi A., Della Ratta E., Livi U., Sharoni E., Werner P., De Vincentiis C., Di Eusanio M., Kocher A., Antona C., Miraldi F., Troise G., Solinas M., Maisano F., Laufer G., Musumeci F., Andreas M., Russo, M, Di Mauro, M, Saitto, G, Lio, A, Berretta, P, Taramasso, M, Scrofani, R, Della Corte, A, Sponga, S, Greco, E, Saccocci, M, Calafiore, A, Bianchi, G, Leviner, D, Biondi, A, Della Ratta, E, Livi, U, Sharoni, E, Werner, P, De Vincentiis, C, Di Eusanio, M, Kocher, A, Antona, C, Miraldi, F, Troise, G, Solinas, M, Maisano, F, Laufer, G, Musumeci, F, Andreas, M, Russo M., Di Mauro M., Saitto G., Lio A., Berretta P., Taramasso M., Scrofani R., Della Corte A., Sponga S., Greco E., Saccocci M., Calafiore A., Bianchi G., Leviner D. B., Biondi A., Della Ratta E., Livi U., Sharoni E., Werner P., De Vincentiis C., Di Eusanio M., Kocher A., Antona C., Miraldi F., Troise G., Solinas M., Maisano F., Laufer G., Musumeci F., and Andreas M.

Abstract

Background: Isolated tricuspid valve (TV) surgery is a rare procedure generally considered at high risk for perioperative mortality and poor long-term outcomes. Surgical treatment can be performed with either an arrested heart (AH) or beating heart (BH) technique. The aim of this study was to compare the outcomes of isolated tricuspid surgery with 2 different approaches. Methods: The Surgical-Tricuspid Study is a multicenter international retrospective study enrolling adult patients who underwent isolated TV procedures (n = 406; age 56 ± 16 years; 56% female) at 13 international sites. The AH and BH strategies were performed in 253 and 153 patients, respectively. Propensity score-matched analysis was used to compare groups. Results: After matching, 129 pairs were obtained and analyzed. The 30-day mortality rate was 6.2% versus 5.0% in the AH and BH groups, respectively (P = .9). The rates of acute renal failure requiring replacement therapy (10% versus 3%; P = .02) and stroke (1.6% versus 0%; P = .08) were numerically higher in the AH group. The 6-year survival rate was 67% ± 6% versus 78% ± 5% in the AH and BH groups, respectively (P = .18), whereas freedom from cardiac death was 75% ± 5% versus 84% ± 4% (P = .21). The 6-year composite cardiac end point of cardiac death and reoperation rate was 60% ± 9% versus 86% ± 5% (P = .024) comparing AH-TV replacement and BH-TV repair groups. Conclusions: Isolated TV surgery performed with a BH strategy is a safe option and resulted in a trend of increased long-term survival and freedom from reoperation compared with the standard AH technique. Patients undergoing BH valve repair had the best long-term outcome.

Published
2022

7. Durability of bioprosthetic aortic valve replacement in patients under the age of 60 years-1-year follow-up from the prospective INDURE registry

Author

Meuris, B, Roussel, JC, Borger, MA, Siepe, M, Stefano, P, Laufer, G, Langanay, T, Theron, A, Grabenwöger, M, Binder, K, Demers, P, Pessotto, R, van Leeuwen, W, Bourguignon, T, Canovas, S, Mariscalco, G, Coscioni, E, Dagenais, F, Wendler, O, Polvani, G, Eden, M, Botta, B, Bramlage, P, De Paulis, R, Meuris, B, Roussel, JC, Borger, MA, Siepe, M, Stefano, P, Laufer, G, Langanay, T, Theron, A, Grabenwöger, M, Binder, K, Demers, P, Pessotto, R, van Leeuwen, W, Bourguignon, T, Canovas, S, Mariscalco, G, Coscioni, E, Dagenais, F, Wendler, O, Polvani, G, Eden, M, Botta, B, Bramlage, P, and De Paulis, R

Abstract

OBJECTIVES: We report 1-year safety and clinical outcomes in patients <60 years undergoing bioprosthetic surgical aortic valve intervention. METHODS: The INSPIRIS RESILIA Durability Registry is a prospective, multicentre registry to assess clinical outcomes of patients <60 years. Patients with planned SAVR with or without concomitant replacement of the ascending aorta and/or coronary bypass surgery were included. Time-related valve safety, haemodynamic performance and quality of life (QoL) at 1 year were assessed. RESULTS: A total of 421 patients were documented with a mean age of 53.5 years, 76.5% being male and 27.2% in NYHA class III/IV. Outcomes within 30 days included cardiovascular-related mortality (0.7%), time-related valve safety (VARC-2; 5.8%), thromboembolic events (1.7%), valve-related life-threatening bleeding (VARC-2; 4.3%) and permanent pacemaker implantation (3.8%). QoL was significantly increased at 6 months and sustained at 1 year. Freedom from all-cause mortality at 1 year was 98.3% (95% confidence interval 97.1; 99.6) and 81.8% were NYHA I versus 21.9% at baseline. No patient developed structural valve deterioration stage 3 (VARC-3). The mean aortic pressure gradient was 12.6 mmHg at 1 year and the effective orifice area was 1.9 cm2. CONCLUSIONS: The 1-year data from the INSPIRIS RESILIA valve demonstrate good safety and excellent haemodynamic performance as well as an early QoL improvement. Clinical trial registration: clinicaltrials.gov: NCT03666741.

Published
2023

21. Clinical outcomes of pacemaker implantations before and after cancer diagnosis

Author

Riesenhuber, M, primary, Spannbauer, A, additional, Gwechenberger, M, additional, Pezawas, T, additional, Schukro, C, additional, Stix, G, additional, Goliasch, G, additional, Anvari, A, additional, Wrba, T, additional, Khazen, C, additional, Andreas, M, additional, Laufer, G, additional, Hengstenberg, C, additional, Bergler-Klein, J, additional, and Gyongyosi, M, additional

Published
2021
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37. Durability of bioprosthetic aortic valves in patients under the age of 60 years - Rationale and design of the international INDURE registry

Author

Meuris, B. (Bart), Borger, M.A. (Michael), Bourguignon, T. (Thierry), Siepe, M. (Matthias), Grabenwöger, M. (Martin), Laufer, G. (Günther), Binder, K. (Konrad), Polvani, G. (Gianluca), Stefano, P. (Pierluigi), Coscioni, E. (Enrico), Leeuwen, W.J. (Wouter) van, Demers, P. (Philippe), Dagenais, F. (Francois), Cánovas, S.J. (Sergio), Theron, A. (Alexis), Langanay, T. (Thierry), Roussel, J.-C. (Jean-Christian), Wendler, O. (Olaf), Mariscalco, G. (Giovanni), Pessotto, R. (Renzo), Botta, B. (Beate), Bramlage, P. (Peter), De Paulis, R. (Ruggero), Meuris, B. (Bart), Borger, M.A. (Michael), Bourguignon, T. (Thierry), Siepe, M. (Matthias), Grabenwöger, M. (Martin), Laufer, G. (Günther), Binder, K. (Konrad), Polvani, G. (Gianluca), Stefano, P. (Pierluigi), Coscioni, E. (Enrico), Leeuwen, W.J. (Wouter) van, Demers, P. (Philippe), Dagenais, F. (Francois), Cánovas, S.J. (Sergio), Theron, A. (Alexis), Langanay, T. (Thierry), Roussel, J.-C. (Jean-Christian), Wendler, O. (Olaf), Mariscalco, G. (Giovanni), Pessotto, R. (Renzo), Botta, B. (Beate), Bramlage, P. (Peter), and De Paulis, R. (Ruggero)

Abstract

Background: There is an ever-growing number of patients requiring aortic valve replacement (AVR). Limited data is available on the long-term outcomes and structural integrity of bioprosthetic valves in younger patients undergoing surgical AVR. Methods: The INSPIRIS RESILIA Durability Registry (INDURE) is a prospective, open-label, multicentre, international registry with a follow-up of 5 years to assess clinical outcomes of patients younger than 60 years who undergo surgical AVR using the INSP

Published
2020
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38. Impact of donor lung quality on post-transplant recipient outcome in the Lung Allocation Score era in Eurotransplant – a historical prospective study

Author

Smits, J.M.A. (J. M A), Gottlieb, J. (Jens), Verschuuren, E.A., Evrard, P. (Patrick), Hoek, R.A.S. (Rogier), Knoop, C. (Christiane), Lang, G. (György), Kwakkel-van Erp, H. (Hanneke), Vos, R. (Robin), Verleden, G. (Geert), Rondelet, B. (Benoit), Hoefer, D. (Daniel), Langer, F. (Frank), Schramm, R. (Rene), Hoetzenecker, K. (Konrad), van Kessel, D.A. (Diana A.), Luijk, B. (Bart), Seghers, L., Deuse, T. (Tobias), Buhl, R. (Roland), Witt, C. (Christian), Strelniece, A. (Agita), Green, D. (Dave), de Vries, E. (Erwin), Laufer, G. (Guenter), Van Raemdonck, D. (Dirk), Smits, J.M.A. (J. M A), Gottlieb, J. (Jens), Verschuuren, E.A., Evrard, P. (Patrick), Hoek, R.A.S. (Rogier), Knoop, C. (Christiane), Lang, G. (György), Kwakkel-van Erp, H. (Hanneke), Vos, R. (Robin), Verleden, G. (Geert), Rondelet, B. (Benoit), Hoefer, D. (Daniel), Langer, F. (Frank), Schramm, R. (Rene), Hoetzenecker, K. (Konrad), van Kessel, D.A. (Diana A.), Luijk, B. (Bart), Seghers, L., Deuse, T. (Tobias), Buhl, R. (Roland), Witt, C. (Christian), Strelniece, A. (Agita), Green, D. (Dave), de Vries, E. (Erwin), Laufer, G. (Guenter), and Van Raemdonck, D. (Dirk)

Abstract

The aim of this study was to investigate whether there is an impact of donation rates on the quality of lungs used for transplantation and whether donor lung quality affects post-transplant outcome in the current Lung Allocation Score era. All consecutive adult LTx performed in Eurotransplant (ET) between January 2012 and December 2016 were included (N = 3053). Donors used for LTx in countries with high donation rate were younger (42% vs. 33% ≤45 years, P < 0.0001), were less often smokers (35% vs. 46%, P < 0.0001), had more often clear chest X-rays (82% vs. 72%, P < 0.0001), had better donor oxygenation ratios (20% vs. 26% with PaO2/FiO2 ≤ 300 mmHg, P < 0.0001), and had better lung donor score values (LDS; 28% vs. 17% with LDS = 6, P < 0.0001) compared with donors used for LTx in countries with low donation rate. Survival rates for the groups LDS = 6 and ≥7 at 5 years were 69.7% and 60.9% (P = 0.007). Lung donor quality significantly impacts on long-term patient survival. Countries with a low donation rate are more oriented to using donor lungs with a lesser quality compared to countries with a high donation rate. Instead of further stretching donor eligibility criteria, the full potential of the donor pool should be realized.

Published
2020
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39. Durability of bioprosthetic aortic valves in patients under the age of 60years-rationale and design of the international INDURE registry

Author

Meuris, B, Borger, MA, Bourguignon, T, Siepe, M, Grabenwoger, M, Laufer, G, Binder, K, Polvani, G, Di Stefano, P, Coscioni, E, van Leeuwen, Wouter, Demers, P, Dagenais, F, Canovas, S, Theron, A, Langanay, T, Roussel, JC, Wendler, O, Mariscalco, G, Pessotto, R, Botta, B, Bramlage, P, De Paulis, R, Meuris, B, Borger, MA, Bourguignon, T, Siepe, M, Grabenwoger, M, Laufer, G, Binder, K, Polvani, G, Di Stefano, P, Coscioni, E, van Leeuwen, Wouter, Demers, P, Dagenais, F, Canovas, S, Theron, A, Langanay, T, Roussel, JC, Wendler, O, Mariscalco, G, Pessotto, R, Botta, B, Bramlage, P, and De Paulis, R

Published
2020

40. Exceptional LAS Requests in Eurotransplant: Analysis of an 8-year Effort to Improve Lung Allocation for Precarious Patients

Author

Longziekten, Infection & Immunity, Vos, R., Smits, J. M., Hoek, R., Green, D., Evrard, P., Knoop, C., Verleden, G. M., Rondelet, B., Kwakkel-vanErp, J. M., Seghers, L., van Kessel, D. A., Luijk, B., Verschuuren, E. A., Lang, G., Hoetzenecker, K., Laufer, G., Hoefer, D., Langer, F., Schramm, R., Deuse, T., Buhl, R., Witt, C., Gottlieb, J., Longziekten, Infection & Immunity, Vos, R., Smits, J. M., Hoek, R., Green, D., Evrard, P., Knoop, C., Verleden, G. M., Rondelet, B., Kwakkel-vanErp, J. M., Seghers, L., van Kessel, D. A., Luijk, B., Verschuuren, E. A., Lang, G., Hoetzenecker, K., Laufer, G., Hoefer, D., Langer, F., Schramm, R., Deuse, T., Buhl, R., Witt, C., and Gottlieb, J.

Published
2020

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