Author: "Laufenberg-Feldmann, Rita" - Searchworks@Jio Institute Digital Library Search Results

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1. High Positive End-expiratory Pressure (PEEP) with Recruitment Maneuvers versus Low PEEP during General Anesthesia for Surgery: A Bayesian Individual Patient Data Meta-analysis of Three Randomized Clinical Trials

Author: Mazzinari, Guido, Zampieri, Fernando G., Ball, Lorenzo, Campos, Niklas S., Bluth, Thomas, Hemmes, Sabrine N. T., Ferrando, Carlos, Librero, Julian, Soro, Marina, Pelosi, Paolo, Gama de Abreu, Marcelo, Schultz, Marcus J., Serpa Neto, Ary, Campos, Niklas S., Bluth, Thomas, Hemmes, Sabrine N.T., Ferrando, Carlos, Pelosi, Paolo, de Abreu, Marcelo Gama, Schultz, Marcus J., Neto, Ary Serpa, Campos, Niklas S., Bluth, Thomas, Hemmes, Sabrine N.T., Librero, Julian, Pozo, Natividad, Ferrando, Carlos, Ball, Lorenzo, Mazzinari, Guido, Pelosi, Paolo, de Abreu, Marcelo Gama, Schultz, Marcus J., Neto, Ary Serpa, Hemmes, Sabrine N.T., Gama de Abreu, Marcelo, Severgnini, Paolo, Hollmann, Markus W., Binnekade, Jan M., Wrigge, Hermann, Canet, Jaume, Hiesmayr, Michael, Schmid, Werner, Tschernko, Edda, Jaber, Samir, Hedenstierna, Göran, Putensen, Christian, Pelosi, Paolo, Schultz, Marcus J., Marti, Agnes, Bacuzzi, Alessandro, Brodhun, Alexander, Molin, Alexandre, Merten, Alfred, Parera, Ana, Brunelli, Andrea, Cortegiani, Andrea, Güldner, Andreas, Reske, Andreas W., Gratarola, Angelo, Giarratano, Antonino, Bastin, Bea, Heyse, Bjorn, Mazul-Sunko, Branka, Amantea, Bruno, Barberis, Bruno, Putensen, Christian, Uhlig, Christopher, Minguez Marín, Conrado, Celentano, Cristian, La Bella, Daniela, D’Antini, David, Velghe, David, Sulemanji, Demet, De Robertis, Edoardo, Hartmann, Eric, Montalto, Francesca, Tropea, Francesco, Mills, Gary H., Cinnella, Gilda, Rocca, Giorgio Della, Caggianelli, Girolamo, Pellerano, Giulia, Mollica, Giuseppina, Bugedo, Guillermo, Wrigge, Hermann, Mulier, Jan-Paul, Vandenbrande, Jeroen, Geib, Johann, Yaqub, Jonathan, Florez, Jorge, Mayoral, Juan F., Sprung, Juraj, Van Limmen, Jurgen, Bos, Lieuwe D.J., de Baerdemaeker, Luc, Jamaer, Luc, Spagnolo, Luigi, Strys, Lydia, Granell Gil, Manuel, de Abreu, Marcelo Gama, Vidal Melo, Marcos F., Schultz, Marcus J., Unzueta, Maria Carmen, Moral, Maria Victoria, Ferner, Marion, Hollmann, Markus W., Weiss, Martin, Vanoni, Massimo, Schaefer, Maximilian S., Prieto, Mercè, Grio, Michele, Severgnini, Paolo, Spieth, Peter Markus, Simon, Philipp, Bodger, Phoebe, Sierra, Pilar, Laufenberg-Feldmann, Rita, Rusca, Roberta, Proietti, Rodolfo, Hemmes, Sabrine N.T., Raineri, Santi Maurizio, Caroleo, Santo, Sabaté, Sergi, De Hert, Stefan, Pezzato, Stefano, Treschan, Tanja A., Goranovic, Tatjana, Koch, Thea, Bluth, Thomas, Kiss, Thomas, Perilli, Valter, Cegarra, Virginia, Schmid, Werner, Ferrando, Carlos, Belda, Javier, Soro, Marina, Canet, Jaume, Unzueta, Carmen, Suarez-Sipmann, Fernando, Librero, Julián, Llombart, Alicia, Rovira, Lucas, Granell, Manuel, Aldecoa, César, Diaz-Cambronero, Oscar, Balust, Jaume, Garutti, Ignacio, Gonzalez, Rafael, Gallego, Lucia, del Valle, Santiago Garcia, Redondo, Javier, Pestaña, David, Rodríguez, Aurelio, García, Javier, de la Matta, Manuel, Ibáñez, Maite, Barrios, Francisco, Hernández, Samuel, Torres, Vicente, Peiró, Salvador, Pozo, Natividad, Villena, Abigail, Carramiñana, Albert, Gallego-Casilda, Alberto, Duca, Alejandro, Alcón, Amalia, Miñana, Amanda, Asensio, Ana, Colás, Ana, Isabel Galve, Ana, Izquierdo, Ana, Jurado, Ana, María Pérez, Ana, Mugarra, Ana, Parera, Ana, Brunelli, Andrea, Gutierrez, Andrea, De Miguel, Ángeles, Lozano, Angels, Katime, Antonio, Romero, Antonio, Garrigues, Beatriz, Ayas, Begoña, Arocas, Blanca, Delgado, Carlos, Fernández, Carmen, Romero, Carolina, Gallego, Clara, Garcés, Cristina, Lisbona, Cristina, Parrilla, Cristina, López-Herrera, Daniel, González, Domingo, Llamazares, Eduardo, Del Rio, Elena, Lozano, Elena, Pastor, Ernesto, Chamorro, Estefanía, Gracia, Estefanía, Sánchez, Ester, Romero, Esther, Díez, Fernando, Serralta, Ferran, Daviu, Francisco, Sandín, Francisco, Aguilar, Gerardo, Tusman, Gerardo, Azparren, Gonzalo, Martínez-Pallí, Graciela, Mazzinari, Guido, Benítez, Inmaculada, Hernandéz, Inmaculada, India, Inmaculada, León, Irene, Fuentes, Isabel, Ruiz, Isabel, Puig, Jaume, Ignacio Román, Javie, Acosta, Jesús, Rico, Jesús, Olmedo, Jonathan, Carbonell, Jose A., Alonso, Jose M., María Pérez, Jose, Miguel Marcos, Jose, Navarro, Jose, Valdivia, Jose, Carrizo, Juan, Piqueras, Laura, Soriano, Laura, Vaquero, Laura, Miguel, Lisset, Muñoz, Lorena, Valencia, Lucia, Olmedilla, Luis, Etulain, Ma Justina, Tisner, Manuel, Barrio, María, Dolores Alonso, María, García, María, Hernández, María J., José Alberola, María, Parra, María, Pilar Argente, María, Vila, María, De Fez, Mario, Agilaga, Marta, Gine, Marta, Ayuso, Mercedes, García, Mercedes, Bejarano, Natalia, Peña, Natalia, Ojeda, Nazario, Martínez, Nilda, García, Nuria, Padrón, Oto, García, Pablo, Valls, Paola, Cruz, Patricia, Piñeiro, Patricia, Charco, Pedro, Anaya, Rafael, López, Ramiro, Rodríguez, Rayco, Martínez, Rocío, Pujol, Roger, Dosdá, Rosa, Lardies, Rosa, Díaz, Ruben, Villazala, Rubén, Zapatero, Sara, Cabrera, Sergio, Sánchez, Sergio, Martin, Silvia, Diaz, Suzana, Franco, Tania, Moreno, Tania, Socorro, Tania, Gilabert, Vicente, Balandrón, Victor, Moral, Victoria, Cegarra, Virgina, Varón, Viviana, Bluth, Thomas, Serpa Neto, Ary, Bobek, Ilona, Canet, Jaume, Cinnella, Gilda, de Baerdemaeker, Luc, Gregoretti, Cesare, Hedenstierna, Göran, Hemmes, Sabrine N.T., Hiesmayr, Michael, Hollmann, Markus W., Jaber, Samir, Laffey, John, Licker, Marc-Joseph, Markstaller, Klaus, Matot, Idit, Mills, Gary H., Mulier, Jan Paul, Putensen, Christian, Rossaint, Rolf, Schmitt, Jochen, Senturk, Mert, Severgnini, Paolo, Sprung, Juraj, Vidal Melo, Marcos F., Wrigge, Hermann, Schultz, Marcus J., Pelosi, Paolo, de Abreu, Marcelo Gama, Abelha, Fernando, Abitağaoğlu, Sühayla, Achilles, Marc, Adebesin, Afeez, Adriaensens, Ine, Ahene, Charles, Akbar, Fatima, Al Harbi, Mohammed, Al Khoury al Kallab, Rita, Albanel, Xavier, Aldenkortt, Florence, Alfouzan, Rawan Abdullah Saleh, Alruqaie, Reef, Altermatt, Fernando, Araujo, Bruno Luís de Castro, Arbesú, Genaro, Artsi, Hanna, Aurilio, Caterina, Ayanoglu, Omer Hilmi, Bacuzzi, Alessandro, Baig, Harris, Baird, Yolanda, Balonov, Konstantin, Balust, Jaume, Banks, Samantha, Bao, Xiaodong, Baumgartner, Mélanie, Belda Tortosa, Isabel, Bergamaschi, Alice, Bergmann, Lars, Bigatello, Luca, Biosca Pérez, Elena, Birr, Katja, Bluth, Thomas, Bojaxhi, Elird, Bonenti, Chiara, Bonney, Iwona, Bos, Elke M.E., Bowman, Sara, Braz, Leandro Gobbo, Brugnoni, Elisa, Brull, Sorin J., Brunetti, Iole, Bruni, Andrea, Buenvenida, Shonie L., Busch, Cornelius Johannes, Camerini, Giovanni, Canet, Jaume, Capatti, Beatrice, Carmona, Javiera, Carungcong, Jaime, Carvalho, Marta, Cattan, Anat, Cavaleiro, Carla, Chiumello, Davide, Ciardo, Stefano, Coburn, Mark, Colella, Umberto, Contreras, Victor, Corman Dincer, Pelin, Cotter, Elizabeth, Crovetto, Marcia, Darrah, William, Davies, Simon, de Baerdemaeker, Luc, De Hert, Stefan, Del Cojo Peces, Enrique, Delphin, Ellise, Diaper, John, do Nascimento, Paulo, Jr., Donatiello, Valerio, Dong, Jing, Dourado, Maria do Socorro, Dullenkopf, Alexander, Ebner, Felix, Elgendy, Hamed, Ellenberger, Christoph, Erdoğan Ari, Dilek, Ermert, Thomas, Farah, Fadi, Fernandez-Bustamante, Ana, Ferreira, Cristina, Fiore, Marco, Fonte, Ana, Fortià Palahí, Christina, Galimberti, Andrea, Gama de Abreu, Marcelo, Garofano, Najia, Giaccari, Luca Gregorio, Gilsanz, Fernando, Girrbach, Felix, Gobbi, Luca, Godfried, Marc Bernard, Goettel, Nicolai, Goldstein, Peter A., Goren, Or, Gorlin, Andrew, Granell Gil, Manuel, Gratarola, Angelo, Graterol, Juan, Guyon, Pierre, Haire, Kevin, Harou, Philippe, Helf, Antonia, Hemmes, Sabrine N.T., Hempel, Gunther, Hernández Cádiz, María José, Heyse, Björn, Hollmann, Markus W., Huercio, Ivan, Ilievska, Jasmina, Jakus, Lien, Jeganath, Vijay, Jelting, Yvonne, Jung, Minoa, Kabon, Barbara, Kacha, Aalok, Karaman Ilić, Maja, Karuppiah, Arunthevaraja, Kavas, Ayse Duygu, Keli Barcelos, Gleicy, Kellogg, Todd A., Kemper, Johann, Kerbrat, Romain, Khodr, Suraya, Kienbaum, Peter, Kir, Bunyamin, Kiss, Thomas, Kivrak, Selin, Klarić, Vlasta, Koch, Thea, Köksal, Ceren, Kowark, Ana, Kranke, Peter, Kuvaki, Bahar, Kuzmanovska, Biljana, Laffey, John, Lange, Mirko, Lemos, Marília Freitas de, Licker, Marc-Joseph, López-Baamonde, Manuel, López-Hernández, Antonio, Lopez-Martinez, Mercedes, Luise, Stéphane, MacGregor, Mark, Machado, Humberto S., Magalhães, Danielle, Maillard, Julien, Malerbi, Patrizia, Manimekalai, Natesan, Margarson, Michael, Markstaller, Klaus, Martin, Archer K, Martin, David P., Martin, Yvette N., Martínez-Ocon, Julia, Martin-Loeches, Ignacio, Maseda, Emilio, Matot, Idit, McAuliffe, Niamh, McKenzie, Travis J., Medina, Paulina, Meersch, Melanie, Menzen, Angelika, Mertens, Els, Meurer, Bernd, Meyer-Treschan, Tanja, Miao, Changhong, Micalizzi, Camilla, Milić, Morena, Módolo, Norma Sueli Pinheiro, Moine, Pierre, Mölders, Patrick, Montero-Feijoo, Ana, Moret, Enrique, Muller, Markus K, Murphy, Zoe, Nalwaya, Pramod, Filip, Naumovski, Navalesi, Paolo, Navarro e Lima, Lais Helena, Nesek Adam, Višnja, Neumann, Claudia, Newell, Christopher, Nisnevitch, Zoulfira, Nizamuddin, Junaid, Novazzi, Cecilia, Nunes, Catarina S, O’Connor, Michael, Oprea, Günther, Orhan Sungur, Mukadder, Özbilgin, Şule, Pace, Maria Caterina, Pacheco, Marcos, Packianathaswamy, Balaji, Palma Gonzalez, Estefania, Papaspyros, Fotios, Paredes, Sebastián, Passavanti, Maria Beatrice, Pedemonte, Juan Cristobal, Pelosi, Paolo, Peremin, Sanja, Philipsenburg, Christoph, Pinho, Daniela, Pinho, Silvia, Posthuma, Linda M., Pota, Vincenzo, Preckel, Benedikt, Priani, Paolo, Putensen, Christian, Rached, Mohamed Aymen, Radoeshki, Aleksandar, Ragazzi, Riccardo, Rajamanickam, Tamilselvan, Rajamohan, Arthi, Ramakrishna, Harish, Rangarajan, Desikan, Reiterer, Christian, Renew, J. Ross, Reynaud, Thomas, Rhys, Rhidian, Rivas, Eva, Robitzky, Luisa, Rossaint, Rolf, Rubulotta, Francesca, Sabbatini, Giovanni, Samuels, Jon D, Sanahuja, Josep Martí, Sansone, Pasquale, Santos, Alice, Sayedalahl, Mohamed, Schaefer, Maximilian S., Scharffenberg, Martin, Schiffer, Eduardo, Schliewe, Nadja, Schorer, Raoul, Schultz, Marcus J., Schumann, Roman, Selmo, Gabriele, Sendra, Mar, Senturk, Mert, Severgnini, Paolo, Shaw, Kate, Shosholcheva, Mirjana, Sibai, Abdulrazak, Simon, Philipp, Simonassi, Francesca, Sinno, Claudia, Sivrikoz, Nukhet, Skandalou, Vasiliki, Smith, Neil, Soares, Maria, Socorro Artiles, Tania, Sousa Castro, Diogo, Sousa, Miguel, Spadaro, Savino, Sprung, Juraj, Stamatakis, Emmanouil, Steiner, Luzius A., Stevenazzi, Andrea, Suarez-de-la-Rica, Alejandro, Suppan, Mélanie, Teichmann, Robert, Tena Guerrero, José Maria, Thiel, Bram, Tolós, Raquel, Tucci, Michelle, Turnbull, Zachary A., Turudić, Žana, Unterberg, Matthias, Van Limmen, Jurgen, Van Nieuwenhove, Yves, Van Waesberghe, Julia, Vidal Melo, Marcos Francisco, Vitković, Bibiana, Vivona, Luigi, Vizcaychipi, Marcela, Volta, Carlo Alberto, Weber, Anne, Weingarten, Toby N., Wittenstein, Jakob, Wrigge, Hermann, Wyffels, Piet, Yagüe, Julio, Yates, David, Yavru, Ayşen, Zac, Lilach, and Zhong, Jing
Published: 2025
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2. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author: Hemmes, Sabrine NT., Gama de Abreu, Marcelo, Severgnini, Paolo, Hollmann, Markus W., Binnekade, Jan M., Wrigge, Hermann, Canet, Jaume, Hiesmayr, Michael, Schmid, Werner, Tschernko, Edda, Jaber, Samir, Hedenstierna, Göran, Putensen, Christian, Pelosi, Paolo, Schultz, Marcus J., Marti, Agnes, Bacuzzi, Alessandro, Brodhun, Alexander, Molin, Alexandre, Merten, Alfred, Parera, Ana, Brunelli, Andrea, Cortegiani, Andrea, Güldner, Andreas, Reske, Andreas W., Gratarola, Angelo, Giarratano, Antonino, Bastin, Bea, Heyse, Bjorn, Mazul-Sunko, Branka, Amantea, Bruno, Barberis, Bruno, Uhlig, Christopher, Marín, Conrado Minguez, Celentano, Cristian, La Bella, Daniela, D’Antini, David, Velghe, David, Sulemanji, Demet, De Robertis, Edoardo, Hartmann, Eric, Montalto, Francesca, Tropea, Francesco, Mills, Gary H., Cinnella, Gilda, Della Rocca, Giorgio, Caggianelli, Girolamo, Pellerano, Giulia, Mollica, Giuseppina, Bugedo, Guillermo, Mulier, Jan-Paul, Vandenbrande, Jeroen, Geib, Johann, Yaqub, Jonathan, Florez, Jorge, Mayoral, Juan F., Sprung, Juraj, Van Limmen, Jurgen, Bos, Lieuwe DJ., de Baerdemaeker, Luc, Jamaer, Luc, Spagnolo, Luigi, Strys, Lydia, Gil, Manuel Granell, Vidal Melo, Marcos F., Unzueta, Maria Carmen, Moral, Maria Victoria, Ferner, Marion, Weiss, Martin, Vanoni, Massimo, Schaefer, Maximilian S., Prieto, Mercè, Grio, Michele, Spieth, Peter Markus, Simon, Philipp, Bodger, Phoebe, Sierra, Pilar, Laufenberg-Feldmann, Rita, Rusca, Roberta, Proietti, Rodolfo, Raineri, Santi Maurizio, Caroleo, Santo, Sabaté, Sergi, De Hert, Stefan, Pezzato, Stefano, Treschan, Tanja A., Goranovic, Tatjana, Koch, Thea, Bluth, Thomas, Kiss, Thomas, Perilli, Valter, Cegarra, Virginia, Ferrando, Carlos, Belda, Javier, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Librero, Julián, Llombart, Alicia, Rovira, Lucas, Granell, Manuel, Aldecoa, César, Diaz-Cambronero, Oscar, Balust, Jaume, Garutti, Ignacio, Gonzalez, Rafael, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Javier, Pestaña, David, Rodríguez, Aurelio, García, Javier, Matta, Manuel de la, Ibáñez, Maite, Barrios, Francisco, Hernández, Samuel, Torres, Vicente, Peiró, Salvador, Pozo, Natividad, Villena, Abigail, Carramiñana, Albert, Gallego-Casilda, Alberto, Duca, Alejandro, Alcón, Amalia, Miñana, Amanda, Asensio, Ana, Colás, Ana, Galve, Ana Isabel, Izquierdo, Ana, Jurado, Ana, Pérez, Ana María, Mugarra, Ana, Gutierrez, Andrea, De Miguel, Ángeles, Lozano, Angels, Katime, Antonio, Romero, Antonio, Garrigues, Beatriz, Ayas, Begoña, Arocas, Blanca, Delgado, Carlos, Fernández, Carmen, Romero, Carolina, Gallego, Clara, Garcés, Cristina, Lisbona, Cristina, Parrilla, Cristina, López-Herrera, Daniel, González, Domingo, Llamazares, Eduardo, Del Rio, Elena, Lozano, Elena, Pastor, Ernesto, Chamorro, Estefanía, Gracia, Estefanía, Sánchez, Ester, Romero, Esther, Díez, Fernando, Serralta, Ferran, Daviu, Francisco, Sandín, Francisco, Aguilar, Gerardo, Tusman, Gerardo, Azparren, Gonzalo, Martínez-Pallí, Graciela, Mazzinari, Guido, Benítez, Inmaculada, Hernandéz, Inmaculada, India, Inmaculada, León, Irene, Fuentes, Isabel, Ruiz, Isabel, Puig, Jaume, Román, Javie Ignacio, Acosta, Jesús, Rico-Feijoo, Jesús, Olmedo, Jonathan, Carbonell, Jose A., Alonso, Jose M., Pérez, Jose María, Marcos, Jose Miguel, Navarro, Jose, Valdivia, Jose, Carrizo, Juan, Piqueras, Laura, Soriano, Laura, Vaquero, Laura, Miguel, Lisset, Muñoz, Lorena, Valencia, Lucia, Olmedilla, Luis, Etulain, Mᵃ Justina, Tisner, Manuel, Barrio, María, Alonso, María Dolores, García, María, Hernández, María J., Alberola, María José, Parra, María, Argente, María Pilar, Vila, María, De Fez, Mario, Agilaga, Marta, Gine, Marta, Ayuso, Mercedes, García, Mercedes, Bejarano, Natalia, Peña, Natalia, Ojeda, Nazario, Martínez, Nilda, García, Nuria, Padrón, Oto, García, Pablo, Valls, Paola, Cruz, Patricia, Piñeiro, Patricia, Charco, Pedro, Anaya, Rafael, López, Ramiro, Rodríguez, Rayco, Martínez, Rocío, Pujol, Roger, Dosdá, Rosa, Lardies, Rosa, Díaz, Ruben, Villazala, Rubén, Zapatero, Sara, Cabrera, Sergio, Sánchez, Sergio, Martin, Silvia, Diaz, Suzana, Franco, Tania, Moreno, Tania, Socorro, Tania, Gilabert, Vicente, Balandrón, Victor, Moral, Victoria, Cegarra, Virgina, Varón, Viviana, Abelha, Fernando, Abitağaoğlu, Sühayla, Achilles, Marc, Adebesin, Afeez, Adriaensens, Ine, Ahene, Charles, Akbar, Fatima, Al Harbi, Mohammed, Al Khoury al Kallab, Rita, Albanel, Xavier, Aldenkortt, Florence, Saleh Alfouzan, Rawan Abdullah, Alruqaie, Reef, Altermatt, Fernando, Luís de Castro Araujo, Bruno, Arbesú, Genaro, Artsi, Hanna, Aurilio, Caterina, Ayanoglu, Omer Hilmi, Baig, Harris, Baird, Yolanda, Balonov, Konstantin, Banks, Samantha, Bao, Xiaodong, Baumgartner, Mélanie, Tortosa, Isabel Belda, Bergamaschi, Alice, Bergmann, Lars, Bigatello, Luca, Pérez, Elena Biosca, Birr, Katja, Bojaxhi, Elird, Bonenti, Chiara, Bonney, Iwona, Bos, Elke M.E., Bowman, Sara, Braz, Leandro Gobbo, Brugnoni, Elisa, Brull, Sorin J., Brunetti, Iole, Bruni, Andrea, Buenvenida, Shonie L., Busch, Cornelius Johannes, Camerini, Giovanni, Capatti, Beatrice, Carmona, Javiera, Carungcong, Jaime, Carvalho, Marta, Cattan, Anat, Cavaleiro, Carla, Chiumello, Davide, Ciardo, Stefano, Coburn, Mark, Colella, Umberto, Contreras, Victor, Dincer, Pelin Corman, Cotter, Elizabeth, Crovetto, Marcia, Darrah, William, Davies, Simon, Del Cojo Peces, Enrique, Delphin, Ellise, Diaper, John, Junior, Paulo do Nascimento, Donatiello, Valerio, Dong, Jing, Dourado, Maria do Socorro, Dullenkopf, Alexander, Ebner, Felix, Elgendy, Hamed, Ellenberger, Christoph, Arı, Dilek Erdoğan, Ermert, Thomas, Farah, Fadi, Fernandez-Bustamante, Ana, Ferreira, Cristina, Fiore, Marco, Fonte, Ana, Palahí, Christina Fortià, Galimberti, Andrea, Garofano, Najia, Giaccari, Luca Gregorio, Gilsanz, Fernando, Girrbach, Felix, Gobbi, Luca, Godfried, Marc Bernard, Goettel, Nicolai, Goldstein, Peter A., Goren, Or, Gorlin, Andrew, Graterol, Juan, Guyon, Pierre, Haire, Kevin, Harou, Philippe, Helf, Antonia, Hemmes, Sabrine N.T., Hempel, Gunther, Hernández Cádiz, María José, Heyse, Björn, Huercio, Ivan, Ilievska, Jasmina, Jakus, Lien, Jeganath, Vijay, Jelting, Yvonne, Jung, Minoa, Kabon, Barbara, Kacha, Aalok, Ilić, Maja Karaman, Karuppiah, Arunthevaraja, Kavas, Ayse Duygu, Barcelos, Gleicy Keli, Kellogg, Todd A., Kemper, Johann, Kerbrat, Romain, Khodr, Suraya, Kienbaum, Peter, Kir, Bunyamin, Kivrak, Selin, Klarić, Vlasta, Köksal, Ceren, Kowark, Ana, Kranke, Peter, Kuvaki, Bahar, Kuzmanovska, Biljana, Laffey, John, Lange, Mirko, Freitas de Lemos, Marília, Licker, Marc-Joseph, López-Baamonde, Manuel, López-Hernández, Antonio, Lopez-Martinez, Mercedes, Luise, Stéphane, MacGregor, Mark, Magalhães, Danielle, Maillard, Julien, Malerbi, Patrizia, Manimekalai, Natesan, Margarson, Michael, Markstaller, Klaus, Martin, Archer K., Martin, David P., Martin, Yvette N., Martínez-Ocon, Julia, Martin-Loeches, Ignacio, Maseda, Emilio, Matot, Idit, McAuliffe, Niamh, McKenzie, Travis J., Medina, Paulina, Meersch, Melanie, Menzen, Angelika, Mertens, Els, Meurer, Bernd, Meyer-Treschan, Tanja, Miao, Changhong, Micalizzi, Camilla, Milić, Morena, Pinheiro Módolo, Norma Sueli, Moine, Pierre, Mölders, Patrick, Montero-Feijoo, Ana, Moret, Enrique, Muller, Markus K., Murphy, Zoe, Nalwaya, Pramod, Naumovski, Filip, Navalesi, Paolo, Navarro e Lima, Lais Helena, Adam, Višnja Nesek, Neumann, Claudia, Newell, Christopher, Nisnevitch, Zoulfira, Nizamuddin, Junaid, Novazzi, Cecilia, O'Connor, Michael, Oprea, Günther, Sungur, Mukadder Orhan, Özbilgin, Şule, Pace, Maria Caterina, Pacheco, Marcos, Packianathaswamy, Balaji, Gonzalez, Estefania Palma, Papaspyros, Fotios, Paredes, Sebastián, Passavanti, Maria Beatrice, Pedemonte, Juan Cristobal, Peremin, Sanja, Philipsenburg, Christoph, Pinho, Daniela, Pinho, Silvia, Posthuma, Linda M., Pota, Vincenzo, Preckel, Benedikt, Priani, Paolo, Rached, Mohamed Aymen, Radoeshki, Aleksandar, Ragazzi, Riccardo, Rajamanickam, Tamilselvan, Rajamohan, Arthi, Ramakrishna, Harish, Rangarajan, Desikan, Reiterer, Christian, Renew, J. Ross, Reynaud, Thomas, Rhys, Rhidian, Rivas, Eva, Robitzky, Luisa, Rossaint, Rolf, Rubulotta, Francesca, Machado, Humberto S., Nunes, Catarina S., Sabbatini, Giovanni, Samuels, Jon D., Sanahuja, Josep Martí, Sansone, Pasquale, Santos, Alice, Sayedalahl, Mohamed, Scharffenberg, Martin, Schiffer, Eduardo, Schliewe, Nadja, Schorer, Raoul, Schumann, Roman, Selmo, Gabriele, Sendra, Mar, Senturk, Mert, Shaw, Kate, Shosholcheva, Mirjana, Sibai, Abdulrazak, Simonassi, Francesca, Sinno, Claudia, Sivrikoz, Nukhet, Skandalou, Vasiliki, Smith, Neil, Soares, Maria, Artiles, Tania Socorro, Castro, Diogo Sousa, Sousa, Miguel, Spadaro, Savino, Stamatakis, Emmanouil, Steiner, Luzius A., Stevenazzi, Andrea, Suarez-de-la-Rica, Alejandro, Suppan, Mélanie, Teichmann, Robert, Tena Guerrero, José Maria, Thiel, Bram, Tolós, Raquel, Altun, Gulbin Tore, Tucci, Michelle, Turnbull, Zachary A., Turudić, Žana, Unterberg, Matthias, Van Nieuwenhove, Yves, Van Waesberghe, Julia, Vidal Melo, Marcos Francisco, Vitković, Bibiana, Vivona, Luigi, Vizcaychipi, Marcela, Volta, Carlo Alberto, Weber, Anne, Weingarten, Toby N., Wittenstein, Jakob, Wyffels, Piet, Yagüe, Julio, Yates, David, Yavru, Ayşen, Zac, Lilach, Zhong, Jing, Campos, Niklas S., Librero, Julian, Ball, Lorenzo, and Serpa Neto, A.
Published: 2022
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3. Improving competence and safety in pain medicine: a practical clinical teaching strategy for students combining simulation and bedside teaching

Author: Kurz, Sandra, Lohse, Jana, Buggenhagen, Holger, Schmidtmann, Irene, Laufenberg-Feldmann, Rita, and Engelhard, Kristin
Published: 2021
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4. Effect of Pre-Hospital Ticagrelor During the First 24 h After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction: The ATLANTIC-H24 Analysis

Author: Bougherbal, Rachid, Bouafia, Mohamed Tahar, Chettibi, Mohamed, Nibouche, Djamaleddine, Moklati, Abdelkader, Benalia, Ahmed, Kaid, Omar, Krim, Messaad, Hammett, Christopher, Garrahy, Paul, Jayasinghe, Rohan, Rashford, Stephen, Huber, Kurt, Neunteufl, Thomas, Brussee, Helmut, Alber, Hannes, Weidinger, Franz, Brunner, Michael, Sipoetz, Johann, Prause, Gerhard, Baubin, Michael, Sebald, Dieter, Cantor, Warren, Vijayaraghavan, Ram, Bata, Iqbal, Lavoie, Andrea, Lassen, Jens Flensted, Ravkilde, Jan, Jensen, Lisette Okkels, Christensen, Alf Møl, Toftegaard, Marianne, Köhler, Dennis, Montalescot, Gilles, Ducrocq, Gregory, Danchin, Nicolas, Henry, Patrick, Livarek, Bernard, Berthier, Romain, Hovasse, Thomas, Garot, Philippe, Payot, Laurent, Benamer, Hakim, Esteve, Jean Baptiste, Elhadad, Simon, Teiger, Emmanuel, Bonnet, Jean Louis, Paganelli, Franck, Cottin, Yves, Schiele, François, Thuaire, Christophe, Cayla, Guillaume, Coste, Pierre, Ohlmann, Patrick, Cudraz, Eric Bonnefoy, Lantelme, Pierre, Perret, Thibault, Tron, Christophe, De Labriolle, Axel, Aptecar, Edouardo, Beliard, Olivier, Varenne, Olivier, El Mahmoud, Rami, Filippi-Codaccioni, Emmanuelle, Angoulvant, Denis, Peycher, Patrick, Poitrineau, Olivier, Tabone, Xavier, Ecollan, Patrick, Broche, Claire, Lambert, Yves, Briole, Nicolas, Beruben, Arielle, Porcher, Nicolas, Auffray, Jean-Pierre, Freysz, Marc, Depardieu, Franck, Poubel, David, De La Cousaye, Jean-Emmanuel, Bartier, Jean-Claude, Jardel, Benoît, Boulanger, Bertrand, Labourel, Hervé, Soulat, Louis-Christophe, Lapostolle, Frédéric, Julie, Véronique, Thicoipe, Michel, Capel, Olivier, Stibbe, Olivier, Carli, Pierre, Tazarourte, Karim, Alcouffe, Fabrice, Aboucaya, David, Aubert, Gaële, Kierzek, Gérald, Cahun-Giraud, Séverine, Zeymer, Uwe, Hamm, Christian, Dengler, Thomas, Prondzinsky, Roland, Biever, Paul Marc, Schäfer, Andreas, Seyfarth, Melchior, Lemke, Bernd, Werner, Gerald, Nef, Holger, Steiger, Holger, Leschke, Matthias, Münzel, Thomas, Dell Orto, Marco Campo, Loges, Christian, Schinke, Monika, Koberne, Frank, Reiffen, Hans Peter, Tiroch, Klaus, Wierich, Dirk, Kneussel, Michael, Little, Simon, Sauer, Hartmut, Laufenberg-Feldmann, Rita, Merkely, Béla, Ungi, Imre, Horváth, Iván, Édes, István, Mártai, István, Bolognese, Leonardo, Berti, Sergio, Chiarella, Francesco, Calabria, Paolo, Fineschi, Massimo, Galvani, Marcello, Valgimigli, Marco, Moretti, Luciano, Tespili, Maurizio, Mandó, Massimo, Bermano, Francesco, Biagioni, Robusto, Fabbri, Andrea, Ricciardelli, Adelina, Petroni, Maria Romana, Vatteroni, Umberto Roberto, Palumbo, Francesco, Willems, Frank F., Al Mafragi, Amar, Heestermans, Ton A.A.C.M., Van Eck, Martijn J., Heutz, Wim M.J.M., Meppelder, H.H., Jong, Anika Roukema-de, Van de Pas, Harm, Fillat, Ángel Cequier, Tenas, Manel Sabaté, Ferrer, Josepa Mauri, Peñaranda, Antoni Serra, Ferrer, Joan Ángel, Del Blanco, Bruno García, Guardiola, Faustino Miranda, Ruiz Nodar, Juan Miguel, Romo, Andrés Íñiguez, González, Nicolás Vázquez, Nouche, Ramiro Trillo, De La Llera, Luis Díaz, Hernández García, José María, Rivero-Crespo, Fernando, Hernández, Felipe Hernández, Zamorano Gómez, José Luis, Fárega, Xavier Jiménez, Fernández, Gilberto Alonso, Toboso, José Luis, Carrasco, Mercedes, Barreiro, Victoria, Iglesias Vázquez, José Antonio, Montero, María del Mar Ruiz, Ortiz, Fernando Rosell, Escudero, Guillermo Garcia, Ingelmo, Vicente Sánchez-Brunete, García, Antonio Lara, Janzon, Magnus, Oldgren, Jonas, Calais, Fredrik, Kastberg, Robert, Bergsten, Per-Adolf, Blomberg, Hans, Thörn, Kristian, Skoog, Gunnar, Storey, Robert F., Zaman, Azfar, Gerber, Robert, Ryding, Alisdair, Spence, Mark, Swanson, Neil, Been, Martin, Grosser, Konrad, Schofield, Peter, Mackin, David, Fell, Paul, Quinn, Tom, Foster, Teresa, McManus, David, Carson, Andy, van ’t Hof, Arnoud W., Cantor, Warren J., Cequier, Angel, Collet, Jean-Philippe, Goodman, Shaun G., Hammett, Christopher J., Licour, Muriel, Salhi, Néjoua, Silvain, Johanne, ten Berg, Jurriën M., Tsatsaris, Anne, Vicaut, Eric, and Hamm, Christian W.
Published: 2016
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5. Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis

Author: Serpa Neto, Ary, Bos, Lieuwe D., Campos, Pedro P.Z.A., Hemmes, Sabrine N.T., Bluth, Thomas, Calfee, Carolyn S., Ferner, Marion, Güldner, Andreas, Hollmann, Markus W., India, Inmaculada, Kiss, Thomas, Laufenberg-Feldmann, Rita, Sprung, Juraj, Sulemanji, Demet, Unzueta, Carmen, Vidal Melo, Marcos F., Weingarten, Toby N., Tuip-de Boer, Anita M., Pelosi, Paolo, Gama de Abreu, Marcelo, and Schultz, Marcus J.
Published: 2018
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6. Is ‘anxiety sensitivity’ predictive of postoperative nausea and vomiting?: A prospective observational study

Author: Laufenberg-Feldmann, Rita, Müller, Michael, Ferner, Marion, Engelhard, Kristin, and Kappis, Bernd
Published: 2019
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7. Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial

Author: Meybohm, Patrick, Lindau, Simone, Treskatsch, Sascha, Francis, Roland, Spies, Claudia, Velten, Markus, Wittmann, Maria, Gueresir, Erdem, Stoppe, Christian, Kowark, Ana, Coburn, Mark, Selleng, Sixten, Baschin, Marcel, Jenichen, Gregor, Meersch, Melanie, Ermert, Thomas, Zarbock, Alexander, Kranke, Peter, Kredel, Markus, Helf, Antonia, Laufenberg-Feldmann, Rita, Ferner, Marion, Wittenmeier, Eva, Gürtler, Karl-Heinz, Kienbaum, Peter, de Abreu, Marcel Gama, Sander, Michael, Bauer, Michael, Seyfried, Timo, Gruenewald, Matthias, Choorapoikayil, Suma, Mueller, Markus M., Seifried, Erhard, Brosteanu, Oana, Bogatsch, Holger, Hasenclever, Dirk, Zacharowski, Kai, and LIBERAL Collaboration Group
Published: 2019
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8. Anxiety and its predictive value for pain and regular analgesic intake after lumbar disc surgery - a prospective observational longitudinal study

Author: Laufenberg-Feldmann, Rita, Kappis, Bernd, Cámara, Rafael J. A., and Ferner, Marion
Published: 2018
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9. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author: Campos, Niklas S., primary, Bluth, Thomas, additional, Hemmes, Sabrine N.T., additional, Librero, Julian, additional, Pozo, Natividad, additional, Ferrando, Carlos, additional, Ball, Lorenzo, additional, Mazzinari, Guido, additional, Pelosi, Paolo, additional, Gama de Abreu, Marcelo, additional, Schultz, Marcus J., additional, Serpa Neto, A., additional, Hemmes, Sabrine NT., additional, Severgnini, Paolo, additional, Hollmann, Markus W., additional, Binnekade, Jan M., additional, Wrigge, Hermann, additional, Canet, Jaume, additional, Hiesmayr, Michael, additional, Schmid, Werner, additional, Tschernko, Edda, additional, Jaber, Samir, additional, Hedenstierna, Göran, additional, Putensen, Christian, additional, Marti, Agnes, additional, Bacuzzi, Alessandro, additional, Brodhun, Alexander, additional, Molin, Alexandre, additional, Merten, Alfred, additional, Parera, Ana, additional, Brunelli, Andrea, additional, Cortegiani, Andrea, additional, Güldner, Andreas, additional, Reske, Andreas W., additional, Gratarola, Angelo, additional, Giarratano, Antonino, additional, Bastin, Bea, additional, Heyse, Bjorn, additional, Mazul-Sunko, Branka, additional, Amantea, Bruno, additional, Barberis, Bruno, additional, Uhlig, Christopher, additional, Marín, Conrado Minguez, additional, Celentano, Cristian, additional, La Bella, Daniela, additional, D’Antini, David, additional, Velghe, David, additional, Sulemanji, Demet, additional, De Robertis, Edoardo, additional, Hartmann, Eric, additional, Montalto, Francesca, additional, Tropea, Francesco, additional, Mills, Gary H., additional, Cinnella, Gilda, additional, Della Rocca, Giorgio, additional, Caggianelli, Girolamo, additional, Pellerano, Giulia, additional, Mollica, Giuseppina, additional, Bugedo, Guillermo, additional, Mulier, Jan-Paul, additional, Vandenbrande, Jeroen, additional, Geib, Johann, additional, Yaqub, Jonathan, additional, Florez, Jorge, additional, Mayoral, Juan F., additional, Sprung, Juraj, additional, Van Limmen, Jurgen, additional, Bos, Lieuwe DJ., additional, de Baerdemaeker, Luc, additional, Jamaer, Luc, additional, Spagnolo, Luigi, additional, Strys, Lydia, additional, Gil, Manuel Granell, additional, Vidal Melo, Marcos F., additional, Unzueta, Maria Carmen, additional, Moral, Maria Victoria, additional, Ferner, Marion, additional, Weiss, Martin, additional, Vanoni, Massimo, additional, Schaefer, Maximilian S., additional, Prieto, Mercè, additional, Grio, Michele, additional, Spieth, Peter Markus, additional, Simon, Philipp, additional, Bodger, Phoebe, additional, Sierra, Pilar, additional, Laufenberg-Feldmann, Rita, additional, Rusca, Roberta, additional, Proietti, Rodolfo, additional, Raineri, Santi Maurizio, additional, Caroleo, Santo, additional, Sabaté, Sergi, additional, De Hert, Stefan, additional, Pezzato, Stefano, additional, Treschan, Tanja A., additional, Goranovic, Tatjana, additional, Koch, Thea, additional, Kiss, Thomas, additional, Perilli, Valter, additional, Cegarra, Virginia, additional, Belda, Javier, additional, Soro, Marina, additional, Unzueta, Carmen, additional, Suarez-Sipmann, Fernando, additional, Librero, Julián, additional, Llombart, Alicia, additional, Rovira, Lucas, additional, Granell, Manuel, additional, Aldecoa, César, additional, Diaz-Cambronero, Oscar, additional, Balust, Jaume, additional, Garutti, Ignacio, additional, Gonzalez, Rafael, additional, Gallego, Lucia, additional, Garcia del Valle, Santiago, additional, Redondo, Javier, additional, Pestaña, David, additional, Rodríguez, Aurelio, additional, García, Javier, additional, Matta, Manuel de la, additional, Ibáñez, Maite, additional, Barrios, Francisco, additional, Hernández, Samuel, additional, Torres, Vicente, additional, Peiró, Salvador, additional, Villena, Abigail, additional, Carramiñana, Albert, additional, Gallego-Casilda, Alberto, additional, Duca, Alejandro, additional, Alcón, Amalia, additional, Miñana, Amanda, additional, Asensio, Ana, additional, Colás, Ana, additional, Galve, Ana Isabel, additional, Izquierdo, Ana, additional, Jurado, Ana, additional, Pérez, Ana María, additional, Mugarra, Ana, additional, Gutierrez, Andrea, additional, De Miguel, Ángeles, additional, Lozano, Angels, additional, Katime, Antonio, additional, Romero, Antonio, additional, Garrigues, Beatriz, additional, Ayas, Begoña, additional, Arocas, Blanca, additional, Delgado, Carlos, additional, Fernández, Carmen, additional, Romero, Carolina, additional, Gallego, Clara, additional, Garcés, Cristina, additional, Lisbona, Cristina, additional, Parrilla, Cristina, additional, López-Herrera, Daniel, additional, González, Domingo, additional, Llamazares, Eduardo, additional, Del Rio, Elena, additional, Lozano, Elena, additional, Pastor, Ernesto, additional, Chamorro, Estefanía, additional, Gracia, Estefanía, additional, Sánchez, Ester, additional, Romero, Esther, additional, Díez, Fernando, additional, Serralta, Ferran, additional, Daviu, Francisco, additional, Sandín, Francisco, additional, Aguilar, Gerardo, additional, Tusman, Gerardo, additional, Azparren, Gonzalo, additional, Martínez-Pallí, Graciela, additional, Benítez, Inmaculada, additional, Hernandéz, Inmaculada, additional, India, Inmaculada, additional, León, Irene, additional, Fuentes, Isabel, additional, Ruiz, Isabel, additional, Puig, Jaume, additional, Román, Javie Ignacio, additional, Acosta, Jesús, additional, Rico-Feijoo, Jesús, additional, Olmedo, Jonathan, additional, Carbonell, Jose A., additional, Alonso, Jose M., additional, Pérez, Jose María, additional, Marcos, Jose Miguel, additional, Navarro, Jose, additional, Valdivia, Jose, additional, Carrizo, Juan, additional, Piqueras, Laura, additional, Soriano, Laura, additional, Vaquero, Laura, additional, Miguel, Lisset, additional, Muñoz, Lorena, additional, Valencia, Lucia, additional, Olmedilla, Luis, additional, Etulain, Mᵃ Justina, additional, Tisner, Manuel, additional, Barrio, María, additional, Alonso, María Dolores, additional, García, María, additional, Hernández, María J., additional, Alberola, María José, additional, Parra, María, additional, Argente, María Pilar, additional, Vila, María, additional, De Fez, Mario, additional, Agilaga, Marta, additional, Gine, Marta, additional, Ayuso, Mercedes, additional, García, Mercedes, additional, Bejarano, Natalia, additional, Peña, Natalia, additional, Ojeda, Nazario, additional, Martínez, Nilda, additional, García, Nuria, additional, Padrón, Oto, additional, García, Pablo, additional, Valls, Paola, additional, Cruz, Patricia, additional, Piñeiro, Patricia, additional, Charco, Pedro, additional, Anaya, Rafael, additional, López, Ramiro, additional, Rodríguez, Rayco, additional, Martínez, Rocío, additional, Pujol, Roger, additional, Dosdá, Rosa, additional, Lardies, Rosa, additional, Díaz, Ruben, additional, Villazala, Rubén, additional, Zapatero, Sara, additional, Cabrera, Sergio, additional, Sánchez, Sergio, additional, Martin, Silvia, additional, Diaz, Suzana, additional, Franco, Tania, additional, Moreno, Tania, additional, Socorro, Tania, additional, Gilabert, Vicente, additional, Balandrón, Victor, additional, Moral, Victoria, additional, Cegarra, Virgina, additional, Varón, Viviana, additional, Abelha, Fernando, additional, Abitağaoğlu, Sühayla, additional, Achilles, Marc, additional, Adebesin, Afeez, additional, Adriaensens, Ine, additional, Ahene, Charles, additional, Akbar, Fatima, additional, Al Harbi, Mohammed, additional, Al Khoury al Kallab, Rita, additional, Albanel, Xavier, additional, Aldenkortt, Florence, additional, Saleh Alfouzan, Rawan Abdullah, additional, Alruqaie, Reef, additional, Altermatt, Fernando, additional, Luís de Castro Araujo, Bruno, additional, Arbesú, Genaro, additional, Artsi, Hanna, additional, Aurilio, Caterina, additional, Ayanoglu, Omer Hilmi, additional, Baig, Harris, additional, Baird, Yolanda, additional, Balonov, Konstantin, additional, Banks, Samantha, additional, Bao, Xiaodong, additional, Baumgartner, Mélanie, additional, Tortosa, Isabel Belda, additional, Bergamaschi, Alice, additional, Bergmann, Lars, additional, Bigatello, Luca, additional, Pérez, Elena Biosca, additional, Birr, Katja, additional, Bojaxhi, Elird, additional, Bonenti, Chiara, additional, Bonney, Iwona, additional, Bos, Elke M.E., additional, Bowman, Sara, additional, Braz, Leandro Gobbo, additional, Brugnoni, Elisa, additional, Brull, Sorin J., additional, Brunetti, Iole, additional, Bruni, Andrea, additional, Buenvenida, Shonie L., additional, Busch, Cornelius Johannes, additional, Camerini, Giovanni, additional, Capatti, Beatrice, additional, Carmona, Javiera, additional, Carungcong, Jaime, additional, Carvalho, Marta, additional, Cattan, Anat, additional, Cavaleiro, Carla, additional, Chiumello, Davide, additional, Ciardo, Stefano, additional, Coburn, Mark, additional, Colella, Umberto, additional, Contreras, Victor, additional, Dincer, Pelin Corman, additional, Cotter, Elizabeth, additional, Crovetto, Marcia, additional, Darrah, William, additional, Davies, Simon, additional, Del Cojo Peces, Enrique, additional, Delphin, Ellise, additional, Diaper, John, additional, Junior, Paulo do Nascimento, additional, Donatiello, Valerio, additional, Dong, Jing, additional, Dourado, Maria do Socorro, additional, Dullenkopf, Alexander, additional, Ebner, Felix, additional, Elgendy, Hamed, additional, Ellenberger, Christoph, additional, Arı, Dilek Erdoğan, additional, Ermert, Thomas, additional, Farah, Fadi, additional, Fernandez-Bustamante, Ana, additional, Ferreira, Cristina, additional, Fiore, Marco, additional, Fonte, Ana, additional, Palahí, Christina Fortià, additional, Galimberti, Andrea, additional, Garofano, Najia, additional, Giaccari, Luca Gregorio, additional, Gilsanz, Fernando, additional, Girrbach, Felix, additional, Gobbi, Luca, additional, Godfried, Marc Bernard, additional, Goettel, Nicolai, additional, Goldstein, Peter A., additional, Goren, Or, additional, Gorlin, Andrew, additional, Graterol, Juan, additional, Guyon, Pierre, additional, Haire, Kevin, additional, Harou, Philippe, additional, Helf, Antonia, additional, Hempel, Gunther, additional, Hernández Cádiz, María José, additional, Heyse, Björn, additional, Huercio, Ivan, additional, Ilievska, Jasmina, additional, Jakus, Lien, additional, Jeganath, Vijay, additional, Jelting, Yvonne, additional, Jung, Minoa, additional, Kabon, Barbara, additional, Kacha, Aalok, additional, Ilić, Maja Karaman, additional, Karuppiah, Arunthevaraja, additional, Kavas, Ayse Duygu, additional, Barcelos, Gleicy Keli, additional, Kellogg, Todd A., additional, Kemper, Johann, additional, Kerbrat, Romain, additional, Khodr, Suraya, additional, Kienbaum, Peter, additional, Kir, Bunyamin, additional, Kivrak, Selin, additional, Klarić, Vlasta, additional, Köksal, Ceren, additional, Kowark, Ana, additional, Kranke, Peter, additional, Kuvaki, Bahar, additional, Kuzmanovska, Biljana, additional, Laffey, John, additional, Lange, Mirko, additional, Freitas de Lemos, Marília, additional, Licker, Marc-Joseph, additional, López-Baamonde, Manuel, additional, López-Hernández, Antonio, additional, Lopez-Martinez, Mercedes, additional, Luise, Stéphane, additional, MacGregor, Mark, additional, Magalhães, Danielle, additional, Maillard, Julien, additional, Malerbi, Patrizia, additional, Manimekalai, Natesan, additional, Margarson, Michael, additional, Markstaller, Klaus, additional, Martin, Archer K., additional, Martin, David P., additional, Martin, Yvette N., additional, Martínez-Ocon, Julia, additional, Martin-Loeches, Ignacio, additional, Maseda, Emilio, additional, Matot, Idit, additional, McAuliffe, Niamh, additional, McKenzie, Travis J., additional, Medina, Paulina, additional, Meersch, Melanie, additional, Menzen, Angelika, additional, Mertens, Els, additional, Meurer, Bernd, additional, Meyer-Treschan, Tanja, additional, Miao, Changhong, additional, Micalizzi, Camilla, additional, Milić, Morena, additional, Pinheiro Módolo, Norma Sueli, additional, Moine, Pierre, additional, Mölders, Patrick, additional, Montero-Feijoo, Ana, additional, Moret, Enrique, additional, Muller, Markus K., additional, Murphy, Zoe, additional, Nalwaya, Pramod, additional, Naumovski, Filip, additional, Navalesi, Paolo, additional, Navarro e Lima, Lais Helena, additional, Adam, Višnja Nesek, additional, Neumann, Claudia, additional, Newell, Christopher, additional, Nisnevitch, Zoulfira, additional, Nizamuddin, Junaid, additional, Novazzi, Cecilia, additional, O'Connor, Michael, additional, Oprea, Günther, additional, Sungur, Mukadder Orhan, additional, Özbilgin, Şule, additional, Pace, Maria Caterina, additional, Pacheco, Marcos, additional, Packianathaswamy, Balaji, additional, Gonzalez, Estefania Palma, additional, Papaspyros, Fotios, additional, Paredes, Sebastián, additional, Passavanti, Maria Beatrice, additional, Pedemonte, Juan Cristobal, additional, Peremin, Sanja, additional, Philipsenburg, Christoph, additional, Pinho, Daniela, additional, Pinho, Silvia, additional, Posthuma, Linda M., additional, Pota, Vincenzo, additional, Preckel, Benedikt, additional, Priani, Paolo, additional, Rached, Mohamed Aymen, additional, Radoeshki, Aleksandar, additional, Ragazzi, Riccardo, additional, Rajamanickam, Tamilselvan, additional, Rajamohan, Arthi, additional, Ramakrishna, Harish, additional, Rangarajan, Desikan, additional, Reiterer, Christian, additional, Renew, J. Ross, additional, Reynaud, Thomas, additional, Rhys, Rhidian, additional, Rivas, Eva, additional, Robitzky, Luisa, additional, Rossaint, Rolf, additional, Rubulotta, Francesca, additional, Machado, Humberto S., additional, Nunes, Catarina S., additional, Sabbatini, Giovanni, additional, Samuels, Jon D., additional, Sanahuja, Josep Martí, additional, Sansone, Pasquale, additional, Santos, Alice, additional, Sayedalahl, Mohamed, additional, Scharffenberg, Martin, additional, Schiffer, Eduardo, additional, Schliewe, Nadja, additional, Schorer, Raoul, additional, Schumann, Roman, additional, Selmo, Gabriele, additional, Sendra, Mar, additional, Senturk, Mert, additional, Shaw, Kate, additional, Shosholcheva, Mirjana, additional, Sibai, Abdulrazak, additional, Simonassi, Francesca, additional, Sinno, Claudia, additional, Sivrikoz, Nukhet, additional, Skandalou, Vasiliki, additional, Smith, Neil, additional, Soares, Maria, additional, Artiles, Tania Socorro, additional, Castro, Diogo Sousa, additional, Sousa, Miguel, additional, Spadaro, Savino, additional, Stamatakis, Emmanouil, additional, Steiner, Luzius A., additional, Stevenazzi, Andrea, additional, Suarez-de-la-Rica, Alejandro, additional, Suppan, Mélanie, additional, Teichmann, Robert, additional, Tena Guerrero, José Maria, additional, Thiel, Bram, additional, Tolós, Raquel, additional, Altun, Gulbin Tore, additional, Tucci, Michelle, additional, Turnbull, Zachary A., additional, Turudić, Žana, additional, Unterberg, Matthias, additional, Van Nieuwenhove, Yves, additional, Van Waesberghe, Julia, additional, Vidal Melo, Marcos Francisco, additional, Vitković, Bibiana, additional, Vivona, Luigi, additional, Vizcaychipi, Marcela, additional, Volta, Carlo Alberto, additional, Weber, Anne, additional, Weingarten, Toby N., additional, Wittenstein, Jakob, additional, Wyffels, Piet, additional, Yagüe, Julio, additional, Yates, David, additional, Yavru, Ayşen, additional, Zac, Lilach, additional, and Zhong, Jing, additional
Published: 2022
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10. A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery

Author: Meybohm, Patrick, Bein, Berthold, Brosteanu, Oana, Cremer, Jochen, Gruenewald, Matthias, Stoppe, Christian, Coburn, Mark, Schaelte, Gereon, Böning, Andreas, Niemann, Bernd, Roesner, Jan, Kletzin, Frank, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo F., Bauer, Martin, Stehr, Sebastian N., Kortgen, Andreas, Wittmann, Maria, Baumgarten, Georg, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schön, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Fuernau, Georg, Hasenclever, Dirk, and Zacharowski, Kai
Published: 2015
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11. Additional file 1 of Improving competence and safety in pain medicine: a practical clinical teaching strategy for students combining simulation and bedside teaching

Author: Kurz, Sandra, Lohse, Jana, Buggenhagen, Holger, Schmidtmann, Irene, Laufenberg-Feldmann, Rita, and Engelhard, Kristin
Subjects: ComputingMilieux_THECOMPUTINGPROFESSION, ComputerApplications_MISCELLANEOUS, Data_FILES
Abstract: Additional file 1. Questionnaire. The questionnaire used in your study was developed for this study and is included in the additional files.
Published: 2021
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12. Additional file 2 of Improving competence and safety in pain medicine: a practical clinical teaching strategy for students combining simulation and bedside teaching

Author: Kurz, Sandra, Lohse, Jana, Buggenhagen, Holger, Schmidtmann, Irene, Laufenberg-Feldmann, Rita, and Engelhard, Kristin
Subjects: Data_FILES
Abstract: Additional file 2.
Published: 2021
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13. Neuropathischer Schmerz bei Palliativpatienten

Author: Ferner, Marion, additional and Laufenberg-Feldmann, Rita, additional
Published: 2021
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14. Comparative sequence analysis of theClostridium difficile toxins A and B

Author: von Eichel-Streiber, Christoph, Laufenberg-Feldmann, Rita, Sartingen, Sabine, Schulze, Jörg, and Sauerborn, Markus
Published: 1992
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15. Cloning of Clostridium difficile toxin B gene and demonstration of high N-terminal homology between toxin A and B

Author: von Eichel-Streiber, Christoph, Laufenberg-Feldmann, Rita, Sartingen, Sabine, Schulze, Jörg, and Sauerborn, Markus
Published: 1990
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16. Additional file 3: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery â a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Table S1. List of adjustment variables. (PDF 65 kb)
Published: 2019
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17. Additional file 5: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery â a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Figure S2. Quantile-quantile plot showing the expected distribution of association test statistics across the SNPs compared to the observed values for AF, delirium, MI, renal failure and stroke. a) Adjustment for all other outcomes. b) No adjustment for all other outcomes and composite. (PDF 305 kb)
Published: 2019
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18. Additional file 4: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery – a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Figure S1. Manhattan Plot of genome-wide association with AF, delirium, MI, renal failure and stroke. The x-axis represents the chromosomes in physical order, the y axis showing –log10(p) for all single nucleotide polymorphisms (SNPs). a) Adjustment for all other outcomes: one SNP reached genome-wide significance (p
Published: 2019
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19. Additional file 1: of Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients â the study design of the LIBERAL-Trial

Author: Meybohm, Patrick, Lindau, Simone, Treskatsch, Sascha, Francis, Roland, Spies, Claudia, Velten, Markus, Wittmann, Maria, Gueresir, Erdem, Stoppe, Christian, Kowark, Ana, Coburn, Mark, Selleng, Sixten, Baschin, Marcel, Jenichen, Gregor, Meersch, Melanie, Ermert, Thomas, Zarbock, Alexander, Kranke, Peter, Kredel, Markus, Helf, Antonia, Laufenberg-Feldmann, Rita, Ferner, Marion, Wittenmeier, Eva, Karl-Heinz GĂźrtler, Kienbaum, Peter, Abreu, Marcel, Sander, Michael, Bauer, Michael, Seyfried, Timo, Gruenewald, Matthias, Choorapoikayil, Suma, Mueller, Markus, Seifried, Erhard, Brosteanu, Oana, Bogatsch, Holger, Hasenclever, Dirk, and Zacharowski, Kai
Abstract: SPIRIT 2013 Checklist. Recommended items to address in a clinical trial protocol and related documents*. (DOCX 52 kb)
Published: 2019
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20. Additional file 1: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery â a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Figure S3. English synopsis of study protocol. (PDF 105 kb)
Published: 2019
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21. Additional file 6: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery – a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Table S2. Complete table of SNPs reaching the predefined threshold of p
Published: 2019
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22. Additional file 2: of Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery â a sub-analysis of the RIPHeart-Study

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo, Bauer, Martin, Kortgen, Andreas, Stehr, Sebastian, Wittmann, Maria, Baumgarten, Georg, Struck, Rafael, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Sander, Michael, Treskatsch, Sascha, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Degenhardt, Frauke, Franke, Andre, Soeren Mucha, Tittmann, Lukas, Kohlhaas, Madeline, Fuernau, Georg, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, and Meybohm, Patrick
Abstract: Figure S4. Study protocol of the RIPHeart study. (PDF 4311 kb)
Published: 2019
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23. Palliativmedizin meets Intensivmedizin

Author: Ferner, Marion, additional, Nauck, Friedemann, additional, and Laufenberg-Feldmann, Rita, additional
Published: 2020
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24. Opioid Rotation in Cancer Pain Treatment: A Systematic Review

Author: Schuster, Michael, Bayer, Oliver, Heid, Florian, and Laufenberg-Feldmann, Rita
Subjects: Analgesics, Opioid, Fentanyl, Morphine, Germany, Neoplasms, Humans, Hydromorphone, Pain Management, Original Article, Cancer Pain, Chronic Pain, Oxycodone, Buprenorphine
Abstract: Rotating several different WHO level III opioid drugs is a therapeutic option for patients with chronic cancer-related pain who suffer from inadequate analgesia and/or intolerable side effects. The evidence favoring opioid rotation is controversial, and the current guidelines in Germany and other countries contain only weak recommendations for it.This review is based on pertinent publications retrieved by a systematic review of the literature on opioid rotation for adult patients with chronic cancerrelated pain who are regularly taking WHO level III opioids by the oral or trans - dermal route.9 individual studies involving a total of 725 patients were included in the analysis, and 3 previous systematic reviews of studies involving a total of 2296 patients were also analyzed. Morphine, oxycodone, fentanyl, hydromorphone, and buprenorphine were used as first-line opioid drugs, and hydromorphone, bupre - norphine, tapentadol, fentanyl, morphine, oxymorphone, and methadone were used as second-line opioid drugs. In all of the studies, pain control was achieved for 14 days after each rotation. In most of them, the dose of the new drug introduced in each rotation needed to be increased above the dose initially calculated from a rotation ratio, with the exception of rotations to methadone. The frequency of side effects was only rarely lessened, but patients largely considered the result of opioid rotation to be positive. No particular opioid drug was found to be best.Opioid rotation can improve analgesia and patient satisfaction. The success of opioid rotation appears to depend on the magnitude of the initial dose, among other factors. Tables of equianalgesic doses should be considered no more than a rough guide for determining the dose of the new drug. Rotations to methadone should be carried out under clinical supervision in experienced hands.
Published: 2018

25. Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial

Author: LIBERAL Collaboration Group, Meybohm, Patrick, Lindau, Simone, Treskatsch, Sascha, Francis, Roland, Spies, Claudia, Velten, Markus, Wittmann, Maria, Güresir, Erdem Özer, Stoppe, Christian, Kowark, Ana, Coburn, Mark, Selleng, Sixten, Baschin, Marcel, Jenichen, Gregor, Meersch, Melanie, Ermert, Thomas, Zarbock, Alexander, Kranke, Peter, Kredel, Markus, Helf, Antonia, Laufenberg-Feldmann, Rita, Ferner, Marion, Wittenmeier, Eva, Gürtler, Karl-Heinz, Kienbaum, Peter, Abreu, Marcelo Gama de, Sander, Michael, Bauer, Michael, Seyfried, Timo, Grünewald, Matthias Lars, Choorapoikayil, Suma, Müller, Markus M., Seifried, Erhard, Brosteanu, Oana, Bogatsch, Holger, Hasenclever, Dirk, Zacharowski, Kai, LIBERAL Collaboration Group, Meybohm, Patrick, Lindau, Simone, Treskatsch, Sascha, Francis, Roland, Spies, Claudia, Velten, Markus, Wittmann, Maria, Güresir, Erdem Özer, Stoppe, Christian, Kowark, Ana, Coburn, Mark, Selleng, Sixten, Baschin, Marcel, Jenichen, Gregor, Meersch, Melanie, Ermert, Thomas, Zarbock, Alexander, Kranke, Peter, Kredel, Markus, Helf, Antonia, Laufenberg-Feldmann, Rita, Ferner, Marion, Wittenmeier, Eva, Gürtler, Karl-Heinz, Kienbaum, Peter, Abreu, Marcelo Gama de, Sander, Michael, Bauer, Michael, Seyfried, Timo, Grünewald, Matthias Lars, Choorapoikayil, Suma, Müller, Markus M., Seifried, Erhard, Brosteanu, Oana, Bogatsch, Holger, Hasenclever, Dirk, and Zacharowski, Kai
Abstract: Background: Perioperative anaemia leads to impaired oxygen supply with a risk of vital organ ischaemia. In healthy and fit individuals, anaemia can be compensated by several mechanisms. Elderly patients, however, have less compensatory mechanisms because of multiple co-morbidities and age-related decline of functional reserves. The purpose of the study is to evaluate whether elderly surgical patients may benefit from a liberal red blood cell (RBC) transfusion strategy compared to a restrictive transfusion strategy. Methods: The LIBERAL Trial is a prospective, randomized, multicentre, controlled clinical phase IV trial randomising 2470 elderly (≥ 70 years) patients undergoing intermediate- or high-risk non-cardiac surgery. Registered patients will be randomised only if Haemoglobin (Hb) reaches ≤9 g/dl during surgery or within 3 days after surgery either to the LIBERAL group (transfusion of a single RBC unit when Hb ≤ 9 g/dl with a target range for the post-transfusion Hb level of 9–10.5 g/dl) or the RESTRICTIVE group (transfusion of a single RBC unit when Hb ≤ 7.5 g/dl with a target range for the post-transfusion Hb level of 7.5–9 g/dl). The intervention per patient will be followed until hospital discharge or up to 30 days after surgery, whichever occurs first. The primary efficacy outcome is defined as a composite of all-cause mortality, acute myocardial infarction, acute ischaemic stroke, acute kidney injury (stage III), acute mesenteric ischaemia and acute peripheral vascular ischaemia within 90 days after surgery. Infections requiring iv antibiotics with re-hospitalisation are assessed as important secondary endpoint. The primary endpoint will be analysed by logistic regression adjusting for age, cancer surgery (y/n), type of surgery (intermediate- or high-risk), and incorporating centres as random effect. Discussion: The LIBERAL-Trial will evaluate whether a liberal transfusion strategy reduces the occurrence of major adverse events after non-cardiac surgery in
Published: 2019

26. RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow-Up

Author: Meybohm, Patrick, Kohlhaas, Madeline, Boening, Andreas, Niemann, Bernd, Sander, Michael, Roesner, Jan, Kletzin, Frank, Mutlak, Haitham, Westphal, Sabine, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo F., Stoppe, Christian, Bauer, Martin, Stehr, Sebastian N., Kortgen, Andreas, Wittmann, Maria, Baumgarten, Georg, Meyer-Treschan, Tanja, Kienbaum, Peter, Heringlake, Matthias, Schoen, Julika, Treskatsch, Sascha, Gruenewald, Matthias, Smul, Thorsten, Wolwender, Ewa, Schilling, Thomas, Fuernau, Georg, Bogatsch, Holger, Brosteanu, Oana, Hasenclever, Dirk, Zacharowski, Kai, RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study Collaborators, Stevanovic, Ana, Renner, Jochen, Rossaint, Rolf, Felzen, Marc, Goetzenich, Andreas, Moormann, Tobias, Chalk, Katharina, Knuefermann, Pascal, Recht, Thomas, Hoeft, Andreas, Winterhalter, Michael, Iken, Sonja, Bein, Berthold, Wiedenbeck, Carolin, Schwarzmann, Gerhard, Lindau, Simone, Zierer, Andreas, Fichtlscherer, Stephan, Goerlach, Gerold, Wollbrueck, Matthias, Boening, Ursula, Weigand, Markus, Strauchmann, Julia, Albrecht, Martin, Morsbach, Kai U., Paxian, Markus, Reinhard, Konrad, Scholz, Jens, Broch, Ole, Francksen, Helga, Kuhr, Bernd, Heinze, Hermann, Paarmann, Hauke, Cremer, Jochen, Sievers, Hans-Hinrich, Klotz, Stefan, Hachenberg, Thomas, Werner, Christian, Mauff, Susanne, Alms, Angela, Bergt, Stefan, Roewer, Norbert, Coburn, Mark, and Schaelte, Gereon
Subjects: medicine.medical_specialty, Time Factors, Myocardial Infarction, Neurocognitive Disorders, Myocardial Reperfusion Injury, Neuropsychological Tests, 030204 cardiovascular system & hematology, ischemia/reperfusion injury, Risk Assessment, 03 medical and health sciences, Cognition, 0302 clinical medicine, Double-Blind Method, Risk Factors, Ischemia, Germany, Multicenter trial, Clinical Studies, Clinical endpoint, Humans, Medicine, Prospective Studies, 030212 general & internal medicine, Myocardial infarction, Cardiac Surgical Procedures, Prospective cohort study, Propofol, Stroke, Original Research, Cardiovascular Surgery, cardio‐vascular surgery, business.industry, Incidence, Protective Factors, medicine.disease, Surgery, Cardiac surgery, Treatment Outcome, Ischemic Preconditioning, Myocardial, Ischemic preconditioning, remote ischemic preconditioning, Cardiology and Cardiovascular Medicine, business, Anesthetics, Intravenous, Echocardiography, Transesophageal, medicine.drug
Abstract: Background Remote ischemic preconditioning ( RIPC ) has been suggested to protect against certain forms of organ injury after cardiac surgery. Previously, we reported the main results of RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study, a multicenter trial randomizing 1403 cardiac surgery patients receiving either RIPC or sham‐ RIPC . Methods and Results In this follow‐up paper, we present 1‐year follow‐up of the composite primary end point and its individual components (all‐cause mortality, myocardial infarction, stroke and acute renal failure), in a sub‐group of patients, intraoperative myocardial dysfunction assessed by transesophageal echocardiography and the incidence of postoperative neurocognitive dysfunction 5 to 7 days and 3 months after surgery. RIPC neither showed any beneficial effect on the 1‐year composite primary end point ( RIPC versus sham‐ RIPC 16.4% versus 16.9%) and its individual components (all‐cause mortality [3.4% versus 2.5%], myocardial infarction [7.0% versus 9.4%], stroke [2.2% versus 3.1%], acute renal failure [7.0% versus 5.7%]) nor improved intraoperative myocardial dysfunction or incidence of postoperative neurocognitive dysfunction 5 to 7 days (67 [47.5%] versus 71 [53.8%] patients) and 3 months after surgery (17 [27.9%] versus 18 [27.7%] patients), respectively. Conclusions Similar to our main study, RIPC had no effect on intraoperative myocardial dysfunction, neurocognitive function and long‐term outcome in cardiac surgery patients undergoing propofol anesthesia. Clinical Trial Registration URL: https://www.clinicaltrials.gov . Unique identifier: NCT 01067703.
Published: 2018
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27. Improve hip fracture outcome in the elderly patient (iHOPE) : A study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

Author: Kowark, Ana, Adam, Christian, Hildebrand, Frank, Hilgers, Ralf-Dieter, Hoeft, Andreas, Isfort, Susanne, Kienbaum, Peter, Knobe, Mathias, Knuefermann, Pascal, Kranke, Peter, Laufenberg-Feldmann, Rita, Nau, Carla, Ahrens, Jörg, Neuman, Mark D., Olotu, Cynthia, Rex, Christopher, Rossaint, Rolf, Sanders, Robert D., Schmidt, Rene, Schneider, Frank, Siebert, Hartmut, Skorning, Max, Spies, Claudia, Bajbouj, Malek, Vicent, Oliver, Wappler, Frank, Wirtz, Dieter Christian, Wittmann, Maria, Zacharowski, Kai, Zarbock, Alexander, Coburn, Mark, iHOPE study group, Roehl, Anna B., VanWaesberghe, Julia, Bollheimer, Cornelius, Ziemann, Sebastian, Fitzner, Christina, Batista, Joao Pedro, Freitag, Mathias, Dietrich, Claudia, Kalvelage, Christina, Grohe, Christina, Schiemann, Alexander, Schmidt, Katrin, Reichert, Dennis, Borowski, Matthias, Renziehausen, Fenja, Neumann, Claudia, Post, Fenna, Schäfer, Maximilian, Müller, Thomas, Osmers, Anne, Mersmann, Jan, Meybohm, Patrick, Kiefmann, Rainer, Riegel, Ann-Kathrin, Dodel, Richard, Koppert, Wolfgang, Reiffen, Hans-Peter, Ferner, Marion, Heid, Florian, Küllmar, Mira, Meersch, Melanie, Zwissler, Bernhard, Haas, Hansjörg, Peszko, Agneta, Ilies, Christoph, Dolch, Michael, Liener, Ulrich C., Maune, Carolin, Wehmeier, Stefanie, Helf, Antonia, Jelting, Yvonne, Hachenberg, Thomas, Henzler, Dietrich, and iHOPE study group
Subjects: Male, medicine.medical_specialty, Arthroplasty, Replacement, Hip, Medizin, Anesthesia, General, Anesthesia, Spinal, law.invention, Anaesthesia, 03 medical and health sciences, Clinical Trial Protocols as Topic, Postoperative Complications, 0302 clinical medicine, Randomized controlled trial, 030202 anesthesiology, law, Pragmatic Clinical Trials as Topic, Protocol, Clinical endpoint, Humans, Multicenter Studies as Topic, Medicine, General anaesthesia, ddc:610, 030212 general & internal medicine, Aged, Randomized Controlled Trials as Topic, Pain, Postoperative, Hip fracture, geriatric medicine, Hip Fractures, business.industry, Medical record, anaesthesia in orthopaedics, General Medicine, Perioperative, Middle Aged, medicine.disease, anaesthetics, Clinical trial, Telephone interview, Research Design, Physical therapy, Female, business
Abstract: IntroductionHip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia on patient-centred outcomes after hip fracture surgery is sparse.Methods and analysisThe iHOPE study is a pragmatic national, multicentre, randomised controlled, open-label clinical trial with a two-arm parallel group design. In total, 1032 patients with hip fracture (>65 years) will be randomised in an intended 1:1 allocation ratio to receive spinal anaesthesia (n=516) or general anaesthesia (n=516). Outcome assessment will occur in a blinded manner after hospital discharge and inhospital. The primary endpoint will be assessed by telephone interview and comprises the time to the first occurring event of the binary composite outcome of all-cause mortality or new-onset serious cardiac and pulmonary complications within 30 postoperative days. In-hospital secondary endpoints, assessed via in-person interviews and medical record review, include mortality, perioperative adverse events, delirium, satisfaction, walking independently, length of hospital stay and discharge destination. Telephone interviews will be performed for long-term endpoints (all-cause mortality, independence in walking, chronic pain, ability to return home cognitive function and overall health and disability) at postoperative day 30±3, 180±45 and 365±60.Ethics and disseminationiHOPE has been approved by the leading Ethics Committee of the Medical Faculty of the RWTH Aachen University on 14 March 2018 (EK 022/18). Approval from all other involved local Ethical Committees was subsequently requested and obtained. Study started in April 2018 with a total recruitment period of 24 months. iHOPE will be disseminated via presentations at national and international scientific meetings or conferences and publication in peer-reviewed international scientific journals.Trial registration numberDRKS00013644; Pre-results
Published: 2018
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28. Additional file 1: of Anxiety and its predictive value for pain and regular analgesic intake after lumbar disc surgery - a prospective observational longitudinal study

Author: Laufenberg-Feldmann, Rita, Kappis, Bernd, CĂĄmara, Rafael, and Ferner, Marion
Abstract: Attachtment A GAD-7. (DOC 24Â kb)
Published: 2018
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29. Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial

Author: Meybohm, Patrick, primary, Lindau, Simone, additional, Treskatsch, Sascha, additional, Francis, Roland, additional, Spies, Claudia, additional, Velten, Markus, additional, Wittmann, Maria, additional, Gueresir, Erdem, additional, Stoppe, Christian, additional, Kowark, Ana, additional, Coburn, Mark, additional, Selleng, Sixten, additional, Baschin, Marcel, additional, Jenichen, Gregor, additional, Meersch, Melanie, additional, Ermert, Thomas, additional, Zarbock, Alexander, additional, Kranke, Peter, additional, Kredel, Markus, additional, Helf, Antonia, additional, Laufenberg-Feldmann, Rita, additional, Ferner, Marion, additional, Wittenmeier, Eva, additional, Gürtler, Karl-Heinz, additional, Kienbaum, Peter, additional, de Abreu, Marcel Gama, additional, Sander, Michael, additional, Bauer, Michael, additional, Seyfried, Timo, additional, Gruenewald, Matthias, additional, Choorapoikayil, Suma, additional, Mueller, Markus M., additional, Seifried, Erhard, additional, Brosteanu, Oana, additional, Bogatsch, Holger, additional, Hasenclever, Dirk, additional, and Zacharowski, Kai, additional
Published: 2019
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30. Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients – the study design of the LIBERAL-Trial

Author: Meybohm, Patrick, primary, Lindau, Simone, additional, Treskatsch, Sascha, additional, Francis, Roland, additional, Spies, Claudia, additional, Velten, Markus, additional, Wittmann, Maria, additional, Gueresir, Erdem, additional, Stoppe, Christian, additional, Kowark, Ana, additional, Coburn, Mark, additional, Selleng, Sixten, additional, Baschin, Marcel, additional, Jenichen, Gregor, additional, Meersch, Melanie, additional, Ermert, Thomas, additional, Zarbock, Alexander, additional, Kranke, Peter, additional, Kredel, Markus, additional, Helf, Antonia, additional, Laufenberg-Feldmann, Rita, additional, Ferner, Marion, additional, Wittenmeier, Eva, additional, Gürtler, Karl-Heinz, additional, Kienbaum, Peter, additional, de Abreu, Marcel Gama, additional, Sander, Michael, additional, Bauer, Michael, additional, Seyfried, Timo, additional, Gruenewald, Matthias, additional, Choorapoikayil, Suma, additional, Mueller, Markus M., additional, Seifried, Erhard, additional, Brosteanu, Oana, additional, Bogatsch, Holger, additional, Hasenclever, Dirk, additional, and Zacharowski, Kai, additional
Published: 2018
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31. Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

Author: Kowark, Ana, primary, Adam, Christian, additional, Ahrens, Jörg, additional, Bajbouj, Malek, additional, Bollheimer, Cornelius, additional, Borowski, Matthias, additional, Dodel, Richard, additional, Dolch, Michael, additional, Hachenberg, Thomas, additional, Henzler, Dietrich, additional, Hildebrand, Frank, additional, Hilgers, Ralf-Dieter, additional, Hoeft, Andreas, additional, Isfort, Susanne, additional, Kienbaum, Peter, additional, Knobe, Mathias, additional, Knuefermann, Pascal, additional, Kranke, Peter, additional, Laufenberg-Feldmann, Rita, additional, Nau, Carla, additional, Neuman, Mark D, additional, Olotu, Cynthia, additional, Rex, Christopher, additional, Rossaint, Rolf, additional, Sanders, Robert D, additional, Schmidt, Rene, additional, Schneider, Frank, additional, Siebert, Hartmut, additional, Skorning, Max, additional, Spies, Claudia, additional, Vicent, Oliver, additional, Wappler, Frank, additional, Wirtz, Dieter Christian, additional, Wittmann, Maria, additional, Zacharowski, Kai, additional, Zarbock, Alexander, additional, and Coburn, Mark, additional
Published: 2018
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32. RIPHeart (Remote Ischemic Preconditioning for Heart Surgery) Study: Myocardial Dysfunction, Postoperative Neurocognitive Dysfunction, and 1 Year Follow‐Up

Author: Meybohm, Patrick, primary, Kohlhaas, Madeline, additional, Stoppe, Christian, additional, Gruenewald, Matthias, additional, Renner, Jochen, additional, Bein, Berthold, additional, Albrecht, Martin, additional, Cremer, Jochen, additional, Coburn, Mark, additional, Schaelte, Gereon, additional, Boening, Andreas, additional, Niemann, Bernd, additional, Sander, Michael, additional, Roesner, Jan, additional, Kletzin, Frank, additional, Mutlak, Haitham, additional, Westphal, Sabine, additional, Laufenberg‐Feldmann, Rita, additional, Ferner, Marion, additional, Brandes, Ivo F., additional, Bauer, Martin, additional, Stehr, Sebastian N., additional, Kortgen, Andreas, additional, Wittmann, Maria, additional, Baumgarten, Georg, additional, Meyer‐Treschan, Tanja, additional, Kienbaum, Peter, additional, Heringlake, Matthias, additional, Schoen, Julika, additional, Treskatsch, Sascha, additional, Smul, Thorsten, additional, Wolwender, Ewa, additional, Schilling, Thomas, additional, Fuernau, Georg, additional, Bogatsch, Holger, additional, Brosteanu, Oana, additional, Hasenclever, Dirk, additional, Zacharowski, Kai, additional, Stevanovic, Ana, additional, Rossaint, Rolf, additional, Felzen, Marc, additional, Goetzenich, Andreas, additional, Moormann, Tobias, additional, Chalk, Katharina, additional, Knuefermann, Pascal, additional, Recht, Thomas, additional, Hoeft, Andreas, additional, Winterhalter, Michael, additional, Iken, Sonja, additional, Wiedenbeck, Carolin, additional, Schwarzmann, Gerhard, additional, Lindau, Simone, additional, Zierer, Andreas, additional, Fichtlscherer, Stephan, additional, Goerlach, Gerold, additional, Wollbrueck, Matthias, additional, Boening, Ursula, additional, Weigand, Markus, additional, Strauchmann, Julia, additional, Morsbach, Kai U., additional, Paxian, Markus, additional, Reinhard, Konrad, additional, Scholz, Jens, additional, Broch, Ole, additional, Francksen, Helga, additional, Kuhr, Bernd, additional, Heinze, Hermann, additional, Paarmann, Hauke, additional, Sievers, Hans‐Hinrich, additional, Klotz, Stefan, additional, Hachenberg, Thomas, additional, Werner, Christian, additional, Mauff, Susanne, additional, Alms, Angela, additional, Bergt, Stefan, additional, and Roewer, Norbert, additional
Published: 2018
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33. Opioid Rotation in Cancer Pain Treatment

Author: Schuster, Michael, primary, Bayer, Oliver, additional, Heid, Florian, additional, and Laufenberg-Feldmann, Rita, additional
Published: 2018
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34. Improve hip fracture outcome in the elderly patient (iHOPE) : a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

Author: iHOPE study group, Kowark, Ana, Adam, Christian, Ahrens, Jörg, Bajbouj, Malek, Bollheimer, Cornelius, Borowski, Matthias, Dodel, Richard, Dolch, Michael, Hachenberg, Thomas, Henzler, Dietrich, Hildebrand, Frank, Hilgers, Ralf-Dieter, Hoeft, Andreas, Isfort, Susanne, Kienbaum, Peter, Knobe, Mathias, Knüfermann, Pascal, Kranke, Peter, Laufenberg-Feldmann, Rita, Nau, Carla, Neuman, Mark D., Olotu, Cynthia, Rex, Christopher, Rossaint, Rolf, Sanders, Robert D., Schmidt, Rene, Schneider, Frank, Siebert, Hartmut, Skorning, Max, Spies, Claudia, Vicent, Oliver, Wappler, Frank, Wirtz, Dieter Christian, Wittmann, Maria, Zacharowski, Kai, Zarbock, Alexander, Coburn, Mark, iHOPE study group, Kowark, Ana, Adam, Christian, Ahrens, Jörg, Bajbouj, Malek, Bollheimer, Cornelius, Borowski, Matthias, Dodel, Richard, Dolch, Michael, Hachenberg, Thomas, Henzler, Dietrich, Hildebrand, Frank, Hilgers, Ralf-Dieter, Hoeft, Andreas, Isfort, Susanne, Kienbaum, Peter, Knobe, Mathias, Knüfermann, Pascal, Kranke, Peter, Laufenberg-Feldmann, Rita, Nau, Carla, Neuman, Mark D., Olotu, Cynthia, Rex, Christopher, Rossaint, Rolf, Sanders, Robert D., Schmidt, Rene, Schneider, Frank, Siebert, Hartmut, Skorning, Max, Spies, Claudia, Vicent, Oliver, Wappler, Frank, Wirtz, Dieter Christian, Wittmann, Maria, Zacharowski, Kai, Zarbock, Alexander, and Coburn, Mark
Abstract: Introduction: Hip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia on patient-centred outcomes after hip fracture surgery is sparse. Methods and analysis: The iHOPE study is a pragmatic national, multicentre, randomised controlled, open-label clinical trial with a two-arm parallel group design. In total, 1032 patients with hip fracture (>65 years) will be randomised in an intended 1:1 allocation ratio to receive spinal anaesthesia (n=516) or general anaesthesia (n=516). Outcome assessment will occur in a blinded manner after hospital discharge and inhospital. The primary endpoint will be assessed by telephone interview and comprises the time to the first occurring event of the binary composite outcome of all-cause mortality or new-onset serious cardiac and pulmonary complications within 30 postoperative days. In-hospital secondary endpoints, assessed via in-person interviews and medical record review, include mortality, perioperative adverse events, delirium, satisfaction, walking independently, length of hospital stay and discharge destination. Telephone interviews will be performed for long-term endpoints (all-cause mortality, independence in walking, chronic pain, ability to return home cognitive function and overall health and disability) at postoperative day 30±3, 180±45 and 365±60. Ethics and dissemination: iHOPE has been approved by the leading Ethics Committee of the Medical Faculty of the RWTH Aachen University on 14 March 2018 (EK 022/18). Approval from all other involved local Ethical Committees was subsequently requested and obtained. Study started in April 2018 with a total recruitment period of 24 months. iHOPE will be disseminated via presentations at national and international scientific meetings or conferences and publication in peer-reviewed international scientific journals. Tr
Published: 2018

35. Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

Author: Bluth, T., Teichmann, R., Hiesmayr, M., Socorro, Tania, Izquierdo, Ana, Soro, Marina, Granell Gil, Manuel, Hernández Cádiz, María José, Biosca Pérez, Elena, Suarez-de-la-Rica, Alejandro, Lopez-Martinez, Mercedes, Huercio, Iván, Maseda, Emilio, Hollmann, M. W., Yagüe, Julio, Cebrian Moreno, Alba, Rivas, Eva, Lopez-Baamonde, Manuel, Elgendy, Hamed, Sayedalahl, Mohamed, SIibai, Abdul Razak, Yavru, Aysen, Sivrikoz, Nukhet, Karadeniz, Meltem, Jaber, S., Corman Dincer, Pelin, Ayanoglu, Hilmi Omer, Tore Altun, Gulbin, Kavas, Ayse Duygu, Dinc, Bora, Kuvaki, Bahar, Ozbilgin, Sule, Erdogan, Dilek, Koksal, Ceren, Abitagaglu, Suheyla, Laffey, J. G., Aurilio, Caterina, Sansone, Pasquale, Pace, Caterina Maria, Donatiello, Valerio, Mattera, Silvana, Nazareno, Palange, Di Colandrea, Salvatore, Spadaro, Savino, Volta, Carlo Alberto, Ragazzi, Riccardo, Licker, M. J., Ciardo, Stefano, Gobbi, Luca, Severgnini, Paolo, Bacuzzi, Alessandro, Brugnoni, Elisa, Gratarola, Angelo, Micalizzi, Camilla, Simonassi, Francesca, Malerbi, Patrizia, Carboni, Adrea, Markstaller, K., Licker, Marc-Joseph, Dullenkopf, Alexander, Goettel, Nicolai, Nesek Adam, Visnja, Karaman Ilic, Maja, Klaric, Vlasta, Vitkovic, Bibiana, Milic, Morena, Zupcic, Miro, De Baerdemaeker, Luc, Matot, I., De Hert, Stefan, Heyse, Bjorn, Van Limmen, Jurgen, Van Nieuwenhove, Yves, Mertens, Els, Neyrinck, Arne, Mulier, Jan, Kahn, David, Godoroja, Daniela, Martin-Loeches, Martin, Müller, G., Vorotyntsev, Sergiy, Fronchko, Valentyna, Matot, Idit, Goren, Or, Zac, Lilach, Gaszynski, Thomasz, Laffey, Jon, Mills, Gary, Nalwaya, Pramod, Mac Gregor, Mark, Mills, G. H., Paddle, Jonathan, Balaji, Packianathaswamy, Rubulotta, Francesca, Adebesin, Afeez, Margarson, Mike, Davies, Simon, Rangarajan, Desikan, Newell, Christopher, Shosholcheva, Mirjana, Papaspyros, Fotios, Mulier, J. P., Skandalou, Vasiliki, Dzurnakov, Paula, Kiss, T., Putensen, C., Rossaint, Rolf, Schmitt, J., Senturk, M., Serpa Neto, A., Severgnini, P., Sprung, J., Vidal Melo, M. F., Wrigge, H., Schultz, M. J., Bobek, I., Pelosi, P., Gama de Abreu, M., PROBESE investigators, PROtective VEntilation Network (PROVEnet), Clinical Trial Network of the European Society of Anaesthesiology (ESA), Güldner, Andreas, Huhle, Robert, Uhlig, Christopher, Vivona, Luigi, Bergamaschi, Alice, Canet, J., Stevanovic, Ana, Treschan, Tanja, Schaefer, Maximilian, Kienbaum, Peter, Laufenberg-Feldmann, Rita, Bergmann, Lars, Ebner, Felix, Robitzky, Luisa, Mölders, Patrick, Cinnella, G., Unterberg, Matthias, Busch, Cornelius, Achilles, Marc, Menzen, Angelika, Freesemann, Harbert, Putensen, Christian, Machado, Humberto, Cavaleiro, Carla, Ferreira, Cristina, Pinho, Daniela, De Baerdemaeker, L., Carvalho, Marta, Pinho, Sílvia, Soares, Maria, Castro, Diogo Sousa, Abelha, Fernando, Rabico, Rui, Delphin, Ellise, Sprung, Juraj, Weingarten, Toby N., Kellogg, Todd A., Gregoretti, C., Martin, Yvette N., McKenzie, Travis J., Brull, Sorin J., Renew, J. Ross, Ramakrishna, Harish, Fernandez-Bustamante, Ana, Balonov, Konstantin, Baig, Harris R., Kacha, Aalok, Pedemonte, Juan C., Hedenstierna, G., Altermatt, Fernando, Corvetto, Marcia A., Paredes, Sebastian, Carmona, Javiera, Rolle, Augusto, Bos, Elke, Beurskens, Charlotte, Veering, B., Zonneveldt, Harry, Boer, Christa, Hemmes, S. N., Godfried, Marc, Thiel, Bram, Kabon, Barbara, Reiterer, Christian, Canet, Jaume, Tolós, Raquel, Sendra, Mar, González, Miriam, Gómez, Noemí, Ferrando, Carlos, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Bluth T., Teichmann R., Kiss T., Bobek I., Canet J., Cinnella G., De Baerdemaeker L., Gregoretti C., Hedenstierna G., Hemmes S.N., Hiesmayr M., Hollmann M.W., Jaber S., Laffey J.G., Licker M.J., Markstaller K., Matot I., Muller G., Mills G.H., Mulier J.P., Putensen C., Rossaint R., Schmitt J., Senturk M., Serpa Neto A., Severgnini P., Sprung J., Vidal Melo M.F., Wrigge H., Schultz M.J., Pelosi P., Gama de Abreu M., Guldner A., Huhle R., Uhlig C., Vivona L., Bergamaschi A., Stevanovic A., Treschan T., Schaefer M., Kienbaum P., Laufenberg-Feldmann R., Bergmann L., Ebner F., Robitzky L., Molders P., Unterberg M., Busch C., Achilles M., Menzen A., Freesemann H., Machado H., Cavaleiro C., Ferreira C.P., Pinho D., Carvalho M., Pinho S., Soares M., Castro D.S., Abelha F., Rabico R., Delphin E., Weingarten T.N., Kellogg T.A., Martin Y.N., McKenzie T.J., Brull S.J., Renew J.R., Ramakrishna H., Fernandez-Bustamante A., Balonov K., Baig H.R., Kacha A., Pedemonte J.C., Altermatt F., Corvetto M.A., Paredes S., Carmona J., Rolle A., Bos E., Beurskens C., Veering B., Zonneveldt H., Boer C., Godfried M., Thiel B., Kabon B., Reiterer C., Tolos R., Sendra M., Gonzalez M., Gomez N., Ferrando C., Socorro T., Izquierdo A., Soro M., Granell Gil M., Hernandez Cadiz M.J., Biosca Perez E., Suarez-de-la-Rica A., Lopez-Martinez M., Huercio I., Maseda E., Yague J., Cebrian Moreno A., Rivas E., Lopez-Baamonde M., Elgendy H., Sibai A.R., Yavru A., Sivrikoz N., Karadeniz M., Corman Dincer P., Ayanoglu H., Tore Altun G., Kavas A.D., Dinc B., Kuvaki B., Ozbilgin S., Erdogan D., Koksal C., Abitagaglu S., Aurilio C., Sansone P., Pace C.M., Donatiello V., Mattera S., Palange N., Di Colandrea S., Spadaro S., Volta C.A., Ragazzi R., Ciardo S., Gobbi L., Bacuzzi A., Brugnoni E., Gratarola A., Micalizzi C., Simonassi F., Malerbi P., Carboni A., Dullenkopf A., Goettel N., Nesek Adam V., Karaman Ilic M., Klaric V., Vitkovic B., Milic M., Miro Z., De Hert S., Heyse B., Van Limmen J., Van Nieuwenhove Y., Mertens E., Kahn D., Godoroja D., Martin-Loeches M., Vorotyntsev S., Fronchko V., Goren O., Zac L., Gaszynski T., Nalwaya P., Mac Gregor M., Paddle J., Balaji P., Rubulotta F., Adebesin A., Margarson M., Davies S., Rangarajan D., Newell C., Shosholcheva M., Papaspyros F., Skandalou V., Dzurnakova P., Anesthesiology, ACS - Heart failure & arrhythmias, AII - Inflammatory diseases, Intensive Care Medicine, ACS - Diabetes & metabolism, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation, UCL - (SLuc) Département de médecine aiguë, UCL - (SLuc) Service d'anesthésiologie, Bluth, T, Teichmann, R, Kiss, T, Bobek, I, Canet, J, Cinnella, G, De Baerdemaeker, L, Gregoretti, C, Hedenstierna, G, Hemmes, S N, Hiesmayr, M, Hollmann, M W, Jaber, S, Laffey, J G, Licker, M J, Markstaller, K, Matot, I, Müller, G, Mills, G H, Mulier, J P, Putensen, C, Rossaint, R, Schmitt, J, Senturk, M, Serpa Neto, A, Severgnini, P, Sprung, J, Vidal Melo, M F, Wrigge, H, Schultz, M J, Pelosi, P, Gama de Abreu, M, Güldner, A, Huhle, R, Uhlig, C, Vivona, L, Bergamaschi, A, Stevanovic, A, Treschan, T, Schaefer, M, Kienbaum, P, Laufenberg-Feldmann, R, Bergmann, L, Ebner, F, Robitzky, L, Mölders, P, Unterberg, M, Busch, C, Achilles, M, Menzen, A, Freesemann, H, Machado, H, Cavaleiro, C, Ferreira, C, Pinho, D, Carvalho, M, Pinho, S, Soares, M, Castro, D, Abelha, F, Rabico, R, Delphin, E, Weingarten, Tn, Kellogg, Ta, Martin, Yn, Mckenzie, Tj, Brull, Sj, Renew, Jr, Ramakrishna, H, Fernandez-Bustamante, A, Balonov, K, Baig, Hr, Kacha, A, Pedemonte, Jc, Altermatt, F, Corvetto, Ma, Paredes, S, Carmona, J, Rolle, A, Bos, E, Beurskens, C, Veering, B, Zonneveldt, H, Boer, C, Godfried, M, Thiel, B, Kabon, B, Reiterer, C, Tolós, R, Sendra, M, González, M, Gómez, N, Ferrando, C, Socorro, T, Izquierdo, A, Soro, M, Granell Gil, M, Hernández Cádiz, Mj, Biosca Pérez, E, Suarez-de-la-Rica, A, Lopez-Martinez, M, Huercio, I, Maseda, E, Yagüe, J, Cebrian Moreno, A, Rivas, E, Lopez-Baamonde, M, Elgendy, H, Sayedalahl, M, Siibai, Ar, Yavru, A, Sivrikoz, N, Karadeniz, M, Corman Dincer, P, Ayanoglu, Ho, Tore Altun, G, Kavas, Ad, Dinc, B, Kuvaki, B, Ozbilgin, S, Erdogan, D, Koksal, C, Abitagaglu, S, Aurilio, C, Sansone, P, Pace, Mc, Donatiello, V, Mattera, S, Nazareno, P, Di Colandrea, S, Spadaro, Antonino, Volta, Ca, Ragazzi, R, Ciardo, S, Gobbi, L, Bacuzzi, A, Brugnoni, E, Gratarola, A, Micalizzi, C, Simonassi, F, Malerbi, P, Carboni, A, Licker, Mj, Dullenkopf, A, Goettel, N, Nesek Adam, V, Karaman Ilić, M, Klaric, V, Vitkovic, B, Milic, M, Zupcic, M, De Hert, S, Heyse, B, Van Limmen, J, Van Nieuwenhove, Y, Mertens, E, Neyrinck, A, Mulier, J, Kahn, D, Godoroja, D, Martin-Loeches, M, Vorotyntsev, S, Fronchko, V, Goren, O, Zac, L, Gaszynski, T, Laffey, J, Mills, G, Nalwaya, P, Mac Gregor, M, Paddle, J, Balaji, P, Rubulotta, F, Adebesin, A, Margarson, M, Davies, S, Rangarajan, D, Newell, C, Shosholcheva, M, Papaspyros, F, Skandalou, V, and Dzurňáková, P.
Subjects: Male, Lung Diseases, Time Factors, [SDV]Life Sciences [q-bio], Respiratory Medicine and Allergy, medicine.medical_treatment, RESPIRATORY-DISTRESS-SYNDROME, Medicine (miscellaneous), Hemodynamics, Mechanical ventilation, Obesity, Positive end-expiratory pressure, Postoperative pulmonary complication, Recruitment maneuver, Pharmacology (medical), LAPAROSCOPIC BARIATRIC SURGERY, Lung Disease, Body Mass Index, law.invention, Positive-Pressure Respiration, Study Protocol, 0302 clinical medicine, Clinical Protocols, Randomized controlled trial, Risk Factors, 030202 anesthesiology, law, Medicine and Health Sciences, Clinical endpoint, Anesthesia, Respiratory function, 030212 general & internal medicine, Lung, Lungmedicin och allergi, 2. Zero hunger, lcsh:R5-920, ddc:617, respiratory system, Operative, 3. Good health, Treatment Outcome, TIDAL VOLUMES, Research Design, Mechanical ventilation, Positive end-expiratory pressure, Recruitment maneuver, Obesity, Postoperative pulmonary complication, Surgical Procedures, Operative, Breathing, Female, Erratum, lcsh:Medicine (General), ALVEOLAR RECRUITMENT MANEUVER, Human, circulatory and respiratory physiology, medicine.medical_specialty, Time Factor, Anesthesia, General, Lung injury, Humans, Intraoperative Care, Protective Factors, NO, GENERAL-ANESTHESIA, DRIVING PRESSURE, 03 medical and health sciences, medicine, ddc:610, Clinical Protocol, General, Protective Factor, POSTOPERATIVE PULMONARY COMPLICATIONS, Surgical Procedures, INTERNATIONAL CONSENSUS, business.industry, Risk Factor, Surgery, respiratory tract diseases, business, LUNG INJURY
Abstract: Background Postoperative pulmonary complications (PPCs) increase the morbidity and mortality of surgery in obese patients. High levels of positive end-expiratory pressure (PEEP) with lung recruitment maneuvers may improve intraoperative respiratory function, but they can also compromise hemodynamics, and the effects on PPCs are uncertain. We hypothesized that intraoperative mechanical ventilation using high PEEP with periodic recruitment maneuvers, as compared with low PEEP without recruitment maneuvers, prevents PPCs in obese patients. Methods/design The PRotective Ventilation with Higher versus Lower PEEP during General Anesthesia for Surgery in OBESE Patients (PROBESE) study is a multicenter, two-arm, international randomized controlled trial. In total, 2013 obese patients with body mass index ≥35 kg/m2 scheduled for at least 2 h of surgery under general anesthesia and at intermediate to high risk for PPCs will be included. Patients are ventilated intraoperatively with a low tidal volume of 7 ml/kg (predicted body weight) and randomly assigned to PEEP of 12 cmH2O with lung recruitment maneuvers (high PEEP) or PEEP of 4 cmH2O without recruitment maneuvers (low PEEP). The occurrence of PPCs will be recorded as collapsed composite of single adverse pulmonary events and represents the primary endpoint. Discussion To our knowledge, the PROBESE trial is the first multicenter, international randomized controlled trial to compare the effects of two different levels of intraoperative PEEP during protective low tidal volume ventilation on PPCs in obese patients. The results of the PROBESE trial will support anesthesiologists in their decision to choose a certain PEEP level during general anesthesia for surgery in obese patients in an attempt to prevent PPCs. Trial registration ClinicalTrials.gov identifier: NCT02148692. Registered on 23 May 2014; last updated 7 June 2016. Electronic supplementary material The online version of this article (doi:10.1186/s13063-017-1929-0) contains supplementary material, which is available to authorized users.
Published: 2017
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36. Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial

Author: Bluth, T., Teichmann, R., Hiesmayr, M., Socorro, Tania, Izquierdo, Ana, Soro, Marina, Granell Gil, Manuel, Hernández Cádiz, María José, Biosca Pérez, Elena, Suarez-de-la-Rica, Alejandro, Lopez-Martinez, Mercedes, Huercio, Iván, Maseda, Emilio, Hollmann, M. W., Yagüe, Julio, Cebrian Moreno, Alba, Rivas, Eva, Lopez-Baamonde, Manuel, Elgendy, Hamed, Sayedalahl, Mohamed, SIibai, Abdul Razak, Yavru, Aysen, Sivrikoz, Nukhet, Karadeniz, Meltem, Jaber, S., Corman Dincer, Pelin, Ayanoglu, Hilmi Omer, Tore Altun, Gulbin, Kavas, Ayse Duygu, Dinc, Bora, Kuvaki, Bahar, Ozbilgin, Sule, Erdogan, Dilek, Koksal, Ceren, Abitagaglu, Suheyla, Laffey, J. G., Aurilio, Caterina, Sansone, Pasquale, Pace, Caterina Maria, Donatiello, Valerio, Mattera, Silvana, Nazareno, Palange, Di Colandrea, Salvatore, Spadaro, Savino, Volta, Carlo Alberto, Ragazzi, Riccardo, Licker, M. J., Ciardo, Stefano, Gobbi, Luca, Severgnini, Paolo, Bacuzzi, Alessandro, Brugnoni, Elisa, Gratarola, Angelo, Micalizzi, Camilla, Simonassi, Francesca, Malerbi, Patrizia, Carboni, Adrea, Markstaller, K., Licker, Marc-Joseph, Dullenkopf, Alexander, Goettel, Nicolai, Nesek Adam, Visnja, Karaman Ilic, Maja, Klaric, Vlasta, Vitkovic, Bibiana, Milic, Morena, Zupcic, Miro, De Baerdemaeker, Luc, Matot, I., De Hert, Stefan, Heyse, Bjorn, Van Limmen, Jurgen, Van Nieuwenhove, Yves, Mertens, Els, Neyrinck, Arne, Mulier, Jan, Kahn, David, Godoroja, Daniela, Martin-Loeches, Martin, Müller, G., Vorotyntsev, Sergiy, Fronchko, Valentyna, Matot, Idit, Goren, Or, Zac, Lilach, Gaszynski, Thomasz, Laffey, Jon, Mills, Gary, Nalwaya, Pramod, Mac Gregor, Mark, Mills, G. H., Paddle, Jonathan, Balaji, Packianathaswamy, Rubulotta, Francesca, Adebesin, Afeez, Margarson, Mike, Davies, Simon, Rangarajan, Desikan, Newell, Christopher, Shosholcheva, Mirjana, Papaspyros, Fotios, Mulier, J. P., Skandalou, Vasiliki, Dzurnakov, Paula, Kiss, T., Putensen, C., Rossaint, Rolf, Schmitt, J., Senturk, M., Serpa Neto, A., Severgnini, P., Sprung, J., Vidal Melo, M. F., Wrigge, H., Schultz, M. J., Bobek, I., Pelosi, P., Gama de Abreu, M., PROBESE investigators, PROtective VEntilation Network (PROVEnet), Clinical Trial Network of the European Society of Anaesthesiology (ESA), Güldner, Andreas, Huhle, Robert, Uhlig, Christopher, Vivona, Luigi, Bergamaschi, Alice, Canet, J., Stevanovic, Ana, Treschan, Tanja, Schaefer, Maximilian, Kienbaum, Peter, Laufenberg-Feldmann, Rita, Bergmann, Lars, Ebner, Felix, Robitzky, Luisa, Mölders, Patrick, Cinnella, G., Unterberg, Matthias, Busch, Cornelius, Achilles, Marc, Menzen, Angelika, Freesemann, Harbert, Putensen, Christian, Machado, Humberto, Cavaleiro, Carla, Ferreira, Cristina, Pinho, Daniela, De Baerdemaeker, L., Carvalho, Marta, Pinho, Sílvia, Soares, Maria, Castro, Diogo Sousa, Abelha, Fernando, Rabico, Rui, Delphin, Ellise, Sprung, Juraj, Weingarten, Toby N., Kellogg, Todd A., Gregoretti, C., Martin, Yvette N., McKenzie, Travis J., Brull, Sorin J., Renew, J. Ross, Ramakrishna, Harish, Fernandez-Bustamante, Ana, Balonov, Konstantin, Baig, Harris R., Kacha, Aalok, Pedemonte, Juan C., Hedenstierna, G., Altermatt, Fernando, Corvetto, Marcia A., Paredes, Sebastian, Carmona, Javiera, Rolle, Augusto, Bos, Elke, Beurskens, Charlotte, Veering, B., Zonneveldt, Harry, Boer, Christa, Hemmes, S. N., Godfried, Marc, Thiel, Bram, Kabon, Barbara, Reiterer, Christian, Canet, Jaume, Tolós, Raquel, Sendra, Mar, González, Miriam, Gómez, Noemí, Ferrando, Carlos, University Hospital Carl Gustav Carus, Semmelweis Egyetem, Budapest, Hospital Universitari Germans Trias I Pujol, Università degli Studi di Foggia - University of Foggia, Ghent University Hospital, Policlinico P. Giaccone, Palermo, University Hospital, Uppsala, University of Amsterdam [Amsterdam] (UvA), Medizinische Universität Wien = Medical University of Vienna, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Faculdade de Medicina do ABC, São Paulo, University of Insubria, Varese, Mayo Clinic [Rochester], Massachusetts General Hospital [Boston], Universität Leipzig [Leipzig], University of Genoa (UNIGE), University Hospital Carl Gustav Carus Dresden, Dresden University of Technology, and Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Subjects: lcsh:R5-920, Anestesi och intensivvård, Anesthesiology and Intensive Care, business.industry, [SDV]Life Sciences [q-bio], Medicine (miscellaneous), 3. Good health, law.invention, 03 medical and health sciences, Protective ventilation, 0302 clinical medicine, Randomized controlled trial, law, Anesthesia, Ventilation (architecture), Medicine, Pharmacology (medical), 030212 general & internal medicine, business, lcsh:Medicine (General), 030217 neurology & neurosurgery, Positive end-expiratory pressure, ComputingMilieux_MISCELLANEOUS
Abstract: Trials 18(1), 247 (2017). doi:10.1186/s13063-017-1987-3
Published: 2017
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37. Prevalence of pain 6 months after surgery : a prospective observational study

Author: Laufenberg-Feldmann, Rita, Kappis, Bernd, Mauff, Susanne, Schmidtmann, Irene, and Ferner, Marion
Subjects: 610 Medical sciences, 610 Medizin
Published: 2016
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38. Kinetics of plasma biomarkers of inflammation and lung injury in surgical patients with or without postoperative pulmonary complications

Author: Serpa Neto, Ary, primary, Campos, Pedro P.Z.A., additional, Hemmes, Sabrine N.T., additional, Bos, Lieuwe D., additional, Bluth, Thomas, additional, Ferner, Marion, additional, Güldner, Andreas, additional, Hollmann, Markus W., additional, India, Inmaculada, additional, Kiss, Thomas, additional, Laufenberg–Feldmann, Rita, additional, Sprung, Juraj, additional, Sulemanji, Demet, additional, Unzueta, Carmen, additional, Melo, Marcos F. Vidal, additional, Weingarten, Toby N., additional, Boer, Anita M. Tuip–de, additional, Pelosi, Paolo, additional, Gama de Abreu, Marcelo, additional, and Schultz, Marcus J., additional
Published: 2017
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39. Neuropathischer Tumorschmerz

Author: Rolke, Roman, Cuhls, Henning, Féchir, Marcel, Laufenberg-Feldmann, Rita, Gerlach, Christina, Mücke, Martin, and Rolke, Silke
Published: 2015
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40. Prevalence of pain 6 months after surgery: a prospective observational study

Author: Laufenberg-Feldmann, Rita, primary, Kappis, Bernd, additional, Mauff, Susanne, additional, Schmidtmann, Irene, additional, and Ferner, Marion, additional
Published: 2016
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41. Effect of Pre-Hospital Ticagrelor During the First 24 h After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction

Author: Montalescot, Gilles, primary, van ’t Hof, Arnoud W., additional, Bolognese, Leonardo, additional, Cantor, Warren J., additional, Cequier, Angel, additional, Chettibi, Mohamed, additional, Collet, Jean-Philippe, additional, Goodman, Shaun G., additional, Hammett, Christopher J., additional, Huber, Kurt, additional, Janzon, Magnus, additional, Lapostolle, Frédéric, additional, Lassen, Jens Flensted, additional, Licour, Muriel, additional, Merkely, Béla, additional, Salhi, Néjoua, additional, Silvain, Johanne, additional, Storey, Robert F., additional, ten Berg, Jurriën M., additional, Tsatsaris, Anne, additional, Zeymer, Uwe, additional, Vicaut, Eric, additional, Hamm, Christian W., additional, Bougherbal, Rachid, additional, Bouafia, Mohamed Tahar, additional, Nibouche, Djamaleddine, additional, Moklati, Abdelkader, additional, Benalia, Ahmed, additional, Kaid, Omar, additional, Krim, Messaad, additional, Hammett, Christopher, additional, Garrahy, Paul, additional, Jayasinghe, Rohan, additional, Rashford, Stephen, additional, Neunteufl, Thomas, additional, Brussee, Helmut, additional, Alber, Hannes, additional, Weidinger, Franz, additional, Brunner, Michael, additional, Sipoetz, Johann, additional, Prause, Gerhard, additional, Baubin, Michael, additional, Sebald, Dieter, additional, Cantor, Warren, additional, Vijayaraghavan, Ram, additional, Bata, Iqbal, additional, Lavoie, Andrea, additional, Ravkilde, Jan, additional, Jensen, Lisette Okkels, additional, Christensen, Alf Møl, additional, Toftegaard, Marianne, additional, Köhler, Dennis, additional, Montalescot, Gilles, additional, Ducrocq, Gregory, additional, Danchin, Nicolas, additional, Henry, Patrick, additional, Livarek, Bernard, additional, Berthier, Romain, additional, Hovasse, Thomas, additional, Garot, Philippe, additional, Payot, Laurent, additional, Benamer, Hakim, additional, Esteve, Jean Baptiste, additional, Elhadad, Simon, additional, Teiger, Emmanuel, additional, Bonnet, Jean Louis, additional, Paganelli, Franck, additional, Cottin, Yves, additional, Schiele, François, additional, Thuaire, Christophe, additional, Cayla, Guillaume, additional, Coste, Pierre, additional, Ohlmann, Patrick, additional, Cudraz, Eric Bonnefoy, additional, Lantelme, Pierre, additional, Perret, Thibault, additional, Tron, Christophe, additional, De Labriolle, Axel, additional, Aptecar, Edouardo, additional, Beliard, Olivier, additional, Varenne, Olivier, additional, El Mahmoud, Rami, additional, Filippi-Codaccioni, Emmanuelle, additional, Angoulvant, Denis, additional, Peycher, Patrick, additional, Poitrineau, Olivier, additional, Tabone, Xavier, additional, Ecollan, Patrick, additional, Broche, Claire, additional, Lambert, Yves, additional, Briole, Nicolas, additional, Beruben, Arielle, additional, Porcher, Nicolas, additional, Auffray, Jean-Pierre, additional, Freysz, Marc, additional, Depardieu, Franck, additional, Poubel, David, additional, De La Cousaye, Jean-Emmanuel, additional, Bartier, Jean-Claude, additional, Jardel, Benoît, additional, Boulanger, Bertrand, additional, Labourel, Hervé, additional, Soulat, Louis-Christophe, additional, Julie, Véronique, additional, Thicoipe, Michel, additional, Capel, Olivier, additional, Stibbe, Olivier, additional, Carli, Pierre, additional, Tazarourte, Karim, additional, Alcouffe, Fabrice, additional, Aboucaya, David, additional, Aubert, Gaële, additional, Kierzek, Gérald, additional, Cahun-Giraud, Séverine, additional, Hamm, Christian, additional, Dengler, Thomas, additional, Prondzinsky, Roland, additional, Biever, Paul Marc, additional, Schäfer, Andreas, additional, Seyfarth, Melchior, additional, Lemke, Bernd, additional, Werner, Gerald, additional, Nef, Holger, additional, Steiger, Holger, additional, Leschke, Matthias, additional, Münzel, Thomas, additional, Dell Orto, Marco Campo, additional, Loges, Christian, additional, Schinke, Monika, additional, Koberne, Frank, additional, Reiffen, Hans Peter, additional, Tiroch, Klaus, additional, Wierich, Dirk, additional, Kneussel, Michael, additional, Little, Simon, additional, Sauer, Hartmut, additional, Laufenberg-Feldmann, Rita, additional, Ungi, Imre, additional, Horváth, Iván, additional, Édes, István, additional, Mártai, István, additional, Berti, Sergio, additional, Chiarella, Francesco, additional, Calabria, Paolo, additional, Fineschi, Massimo, additional, Galvani, Marcello, additional, Valgimigli, Marco, additional, Moretti, Luciano, additional, Tespili, Maurizio, additional, Mandó, Massimo, additional, Bermano, Francesco, additional, Biagioni, Robusto, additional, Fabbri, Andrea, additional, Ricciardelli, Adelina, additional, Petroni, Maria Romana, additional, Vatteroni, Umberto Roberto, additional, Palumbo, Francesco, additional, Willems, Frank F., additional, Al Mafragi, Amar, additional, Heestermans, Ton A.A.C.M., additional, Van Eck, Martijn J., additional, Heutz, Wim M.J.M., additional, Meppelder, H.H., additional, Jong, Anika Roukema-de, additional, Van de Pas, Harm, additional, Fillat, Ángel Cequier, additional, Tenas, Manel Sabaté, additional, Ferrer, Josepa Mauri, additional, Peñaranda, Antoni Serra, additional, Ferrer, Joan Ángel, additional, Del Blanco, Bruno García, additional, Guardiola, Faustino Miranda, additional, Ruiz Nodar, Juan Miguel, additional, Romo, Andrés Íñiguez, additional, González, Nicolás Vázquez, additional, Nouche, Ramiro Trillo, additional, De La Llera, Luis Díaz, additional, Hernández García, José María, additional, Rivero-Crespo, Fernando, additional, Hernández, Felipe Hernández, additional, Zamorano Gómez, José Luis, additional, Fárega, Xavier Jiménez, additional, Fernández, Gilberto Alonso, additional, Toboso, José Luis, additional, Carrasco, Mercedes, additional, Barreiro, Victoria, additional, Iglesias Vázquez, José Antonio, additional, Montero, María del Mar Ruiz, additional, Ortiz, Fernando Rosell, additional, Escudero, Guillermo Garcia, additional, Ingelmo, Vicente Sánchez-Brunete, additional, García, Antonio Lara, additional, Oldgren, Jonas, additional, Calais, Fredrik, additional, Kastberg, Robert, additional, Bergsten, Per-Adolf, additional, Blomberg, Hans, additional, Thörn, Kristian, additional, Skoog, Gunnar, additional, Zaman, Azfar, additional, Gerber, Robert, additional, Ryding, Alisdair, additional, Spence, Mark, additional, Swanson, Neil, additional, Been, Martin, additional, Grosser, Konrad, additional, Schofield, Peter, additional, Mackin, David, additional, Fell, Paul, additional, Quinn, Tom, additional, Foster, Teresa, additional, McManus, David, additional, and Carson, Andy, additional
Published: 2016
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42. Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery - a sub-analysis of the RIPHeart-Study.

Author: Westphal, Sabine, Stoppe, Christian, Gruenewald, Matthias, Bein, Berthold, Renner, Jochen, Cremer, Jochen, Coburn, Mark, Schaelte, Gereon, Boening, Andreas, Niemann, Bernd, Kletzin, Frank, Roesner, Jan, Strouhal, Ulrich, Reyher, Christian, Laufenberg-Feldmann, Rita, Ferner, Marion, Brandes, Ivo F., Bauer, Martin, Kortgen, Andreas, and Stehr, Sebastian N.
Subjects: COMPLICATIONS of cardiac surgery, ATRIAL fibrillation, MYOCARDIAL infarction, DELIRIUM, ACUTE kidney failure, STROKE, HUMAN genome
Abstract: Background: The aim of our study was the identification of genetic variants associated with postoperative complications after cardiac surgery.Methods: We conducted a prospective, double-blind, multicenter, randomized trial (RIPHeart). We performed a genome-wide association study (GWAS) in 1170 patients of both genders (871 males, 299 females) from the RIPHeart-Study cohort. Patients undergoing non-emergent cardiac surgery were included. Primary endpoint comprises a binary composite complication rate covering atrial fibrillation, delirium, non-fatal myocardial infarction, acute renal failure and/or any new stroke until hospital discharge with a maximum of fourteen days after surgery.Results: A total of 547,644 genotyped markers were available for analysis. Following quality control and adjustment for clinical covariate, one SNP reached genome-wide significance (PHLPP2, rs78064607, p = 3.77 × 10- 8) and 139 (adjusted for all other outcomes) SNPs showed promising association with p < 1 × 10- 5 from the GWAS.Conclusions: We identified several potential loci, in particular PHLPP2, BBS9, RyR2, DUSP4 and HSPA8, associated with new-onset of atrial fibrillation, delirium, myocardial infarction, acute kidney injury and stroke after cardiac surgery.Trial Registration: The study was registered with ClinicalTrials.gov NCT01067703, prospectively registered on 11 Feb 2010. [ABSTRACT FROM AUTHOR]
Published: 2019
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43. Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis.

Author: Neto, Ary Serpa, Bos, Lieuwe D., Campos, Pedro P. Z. A., Hemmes, Sabrine N. T., Bluth, Thomas, Calfee, Carolyn S., Ferner, Marion, Güldner, Andreas, Hollmann, Markus W., India, Inmaculada, Kiss, Thomas, Laufenberg-Feldmann, Rita, Sprung, Juraj, Sulemanji, Demet, Unzueta, Carmen, Melo, Marcos F. Vidal, Weingarten, Toby N., Tuip-deBoer, Anita M., Pelosi, Paolo, and de Abreu, Marcelo Gama
Subjects: LUNG disease diagnosis, CLUSTER analysis (Statistics), COMPARATIVE studies, INFLAMMATORY mediators, INTERNATIONAL relations, LUNG diseases, RESEARCH methodology, MEDICAL cooperation, PREOPERATIVE care, RESEARCH, SURGICAL complications, PHENOTYPES, EVALUATION research, POSITIVE end-expiratory pressure
Abstract: Background: Biological phenotypes have been identified within several heterogeneous pulmonary diseases, with potential therapeutic consequences.Objective: To assess whether distinct biological phenotypes exist within surgical patients, and whether development of postoperative pulmonary complications (PPCs) and subsequent dependence of intra-operative positive end-expiratory pressure (PEEP) differ between such phenotypes.Setting: Operating rooms of six hospitals in Europe and USA.Design: Secondary analysis of the 'PROtective Ventilation with HIgh or LOw PEEP' trial.Patients: Adult patients scheduled for abdominal surgery who are at risk of PPCs.Interventions: Measurement of pre-operative concentrations of seven plasma biomarkers associated with inflammation and lung injury.Main Outcome Measures: We applied unbiased cluster analysis to identify biological phenotypes. We then compared the proportion of patients developing PPCs within each phenotype, and associations between intra-operative PEEP levels and development of PPCs among phenotypes.Results: In total, 242 patients were included. Unbiased cluster analysis clustered the patients within two biological phenotypes. Patients with phenotype 1 had lower plasma concentrations of TNF-α (3.8 [2.4 to 5.9] vs. 10.2 [8.0 to 12.1] pg ml; P < 0.001), IL-6 (2.3 [1.5 to 4.0] vs. 4.0 [2.9 to 6.5] pg ml; P < 0.001) and IL-8 (4.7 [3.1 to 8.1] vs. 8.1 [6.0 to 13.9] pg ml; P < 0.001). Phenotype 2 patients had the highest incidence of PPC (69.8 vs. 34.2% in type 1; P < 0.001). There was no interaction between phenotype and PEEP level for the development of PPCs (43.2% in high PEEP vs. 25.6% in low PEEP in phenotype 1, and 73.6% in high PEEP and 65.7% in low PEEP in phenotype 2; P for interaction = 0.503).Conclusion: Patients at risk of PPCs and undergoing open abdominal surgery can be clustered based on pre-operative plasma biomarker concentrations. The two identified phenotypes have different incidences of PPCs. Biologic phenotyping could be useful in future randomised controlled trials of intra-operative ventilation.Trial Registration: The PROtective Ventilation with HIgh or LOw PEEP trial, including the substudy from which data were used for the present analysis, was registered at ClinicalTrials.gov (NCT01441791). [ABSTRACT FROM AUTHOR]
Published: 2018
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44. Supplementary material to: Opioid Rotation in Cancer Pain Treatment: A Systematic Review.

Author: Schuster, Michael, Bayer, Oliver, Heid, Florian, and Laufenberg-Feldmann, Rita
Abstract: A list of electronic references on opioid rotation in cancer pain treatment is presented that include "Use of Opioid Analgesics in the Treatment of Cancer Pain: Evidence-based Recommendations From the EAPC," "Effects of Opioid Rotation in Chronic Pain Patients: ORTIBARN Study" and "Opioid Rotation: A Therapeutic Choice in the Management of Refractory Cancer Pain."
Published: 2018
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45. Does Interdisciplinary and Multiprofessional Undergraduate Education Increase Students' Self-Confidence and Knowledge Toward Palliative Care? Evaluation of an Undergraduate Curriculum Design for Palliative Care at a German Academic Hospital

Author: Gerlach, Christina, primary, Mai, Sandra, additional, Schmidtmann, Irene, additional, Massen, Clara, additional, Reinholz, Ulrike, additional, Laufenberg-Feldmann, Rita, additional, and Weber, Martin, additional
Published: 2015
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46. Assessing preoperative anxiety using a questionnaire and clinical rating

Author: Laufenberg-Feldmann, Rita, primary and Kappis, Bernd, additional
Published: 2013
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47. Akutschmerztherapie in Pädiatrie und Geriatrie – Akutschmerztherapie im Alter –ein ganzheitlicher Ansatz

Author: Laufenberg-Feldmann, Rita, primary and Jage, Jürgen, additional
Published: 2011
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48. Characterization of polymorphisms in the toxin A and B genes of Clostridium difficile

Author: Rupnik, Maja, primary, Braun, Veit, additional, Soehn, Florian, additional, Janc, Miha, additional, Hofstetter, Monika, additional, Laufenberg-Feldmann, Rita, additional, and Eichel-Streiber, Christoph, additional
Published: 2006
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49. Comparative sequence analysis of the Clostridium difficile toxins A and B.

Author: Eichel-Streiber, Christoph, Laufenberg-Feldmann, Rita, Sartingen, Sabine, Schulze, Jörg, and Sauerborn, Markus
Published: 1992
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50. Cloning of Clostridium difficile toxin B gene and demonstration of high N-terminal homology between toxin A and B.

Author: Eichel-Streiber, Christoph, Laufenberg-Feldmann, Rita, Sartingen, Sabine, Schulze, Jörg, and Sauerborn, Markus
Abstract: High titered Clostridium sordellii lethal toxin antiserum, cross-reactive with C. difficile cytotoxin B (ToxB), was used to isolate toxB fragments from a C. difficile expression library. Recombinant clones containing toxB fragments of the 5′ and 3′ end were isolate. A 2.5-kb HincII fragment of chromosomal DNA overlaps both groups of clones. A partial restriction map of the total toxB gene is presented. The gene is positioned upstream of utxA and toxA toxB has a size of 6.9kb, corresponding to a 250-kDa polypeptide. A partial sequence of the 5′ end of toxB was determined. The sequence contains 398 bp upstream of toxB with a putative Shine-Dalgarno box (AGGAGA) and 609 bp of the toxB open reading frame. The N-terminal 203 amino acids of ToxB were compared with the N-terminal amino acids of the enterotoxin A (ToxA). A homology of 64% of the residues was detected, which proves the relatedness of ToxA and ToxB of C. difficile. [ABSTRACT FROM AUTHOR]
Published: 1990
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