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4. Contributors

5. Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury.

8. Effects of enrichment strategies on outcome of adrecizumab treatment in septic shock: Post-hoc analyses of the phase II adrenomedullin and outcome in septic shock 2 trial

10. Head-to-head comparison of cytokines storm-coagulopathy in septic shock and COVID-19

11. Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial

12. Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study

16. Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial

19. A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentration (AdrenOSS-2)

23. Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial

24. Circulating adrenomedullin estimates survival and reversibility of organ failure in sepsis: the prospective observational multinational Adrenomedullin and Outcome in Sepsis and Septic Shock-1 (AdrenOSS-1) study

25. Erratum: Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y

27. Acute kidney injury in the ICU: from injury to recovery: reports from the 5th Paris International Conference

28. Breakthrough in cardiac arrest: reports from the 4th Paris International Conference

30. Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial.

39. Liver Transplantation and HBsAg-positive Postnecrotic Cirrhosis: Adequate Immunoprophylaxis and delta Virus Co-infection as the Significant Determinants of Long-term Prognosis

40. Impact of oversedation prevention in ventilated critically ill patients: a randomized trial-the AWARE study

41. Fluid challenges in intensive care: the FENICE study: a global inception cohort study

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