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1. Corrigendum: The new Italian registry of infantile thrombosis (RITI): a reflection on its journey, challenges and pitfalls

Author

Maria Federica Pelizza, Matteo Martinato, Anna Rosati, Margherita Nosadini, Paola Saracco, Paola Giordano, Matteo Luciani, Laura Ilardi, Donatella Lasagni, Angelo Claudio Molinari, Rossana Bagna, Antonella Palmieri, Luca Antonio Ramenghi, Massimo Grassi, Mariella Magarotto, Federica Magnetti, Andrea Francavilla, Giuseppe Indolfi, Agnese Suppiej, Chiara Gentilomo, Roberta Restelli, Antonella Tufano, Daniela Tormene, Jacopo Norberto Pin, Clarissa Tona, Davide Meneghesso, Lidia Rota, Marta Conti, Giovanna Russo, Giulia Lorenzoni, Dario Gregori, Stefano Sartori, Paolo Simioni, Collaborators of the R.I.T.I. (Italian and Registry of Infantile Thrombosis), Accorsi Patrizia, Aceto Gabriella, Agnoletti Gabriella, Agostini Manuela, Alfarano Angela, Altieri Elena, Amador Carolina, Antonelli Camilla, Arena Vittoria, Asta Francesca, Baggio Laura, Ballardini Elisa, Baracetti Margherita, Baraldi Eugenio, Barberis Laura, Barisone Elena, Basso Anne Letizia, Battajon Nadia, Bersani Iliana, Biddeci Giada, Biffanti Roberta, Bonardi Claudia Maria, Bonaudo Roberto, Boniver Clementina, Boscarol Gianluca, Bottino Roberto, Bravar Giulia, Brizzi Ilaria, Brolatti Noemi, Braguglia Annabella, Guaragni Brunetta, Bugin Samuela, Calvo Pier Luigi, Capasso Antonella, Capodiferro Donatella, Cappelleri Alessia, Cascarano Maria Teresa, Casellato Susanna, Casini Tommaso, Catarzi Serena, Cavaliere Elena, Cavicchiolo Maria Elena, Celestino Silvia, Celle Maria Elena, Centonze Nicola, Cerutti Alessia, Chakrokh Roksana, Offer Chiara, Chiodin Elisabetta, Chirico Gaetano, Chukhlantseva Natalia, Cifarelli Paola, Cinelli Giulia, Coinu Marisa, Colonna Clara, Comito Donatella, Corato Alessandra, Cordelli Duccio Maria, Crichiutti Giovanni, Cursio Ida, Dagri Arianna, De Maria Beatrice, Del Borrello Giovanni, Di Rienzo Francesca, Doglioni Nicoletta, Dolcemascolo Valentina, Dotta Andrea, Drigo Paola, Drimaco Pietro, Ellero Serena, Falcone Alessandra, Fantauzzi Ambra, Farinasso Daniela, Ferilli Michela, Festa Silvia, Fischer Maximilian, Foiadelli Thomas, Fotzi Ilaria, Francavilla Rosa, Freschi Paola, Gaffuri Marcella, Gallo Elena, Gamalero Lisa, Gandioli Claudia, Garuccio Sergio, Gentile Diletta, Ghionzoli Marco, Giliberti Paola, Greco Filippo, Guariento Chiara, Guidotti Isotta, Iodice Alessandro, Janes Augusta, Laghi Elena, Lampugnani Elisabetta, Lassandro Giuseppe, Laverda Anna Maria, Lazzerotti Alessandra, Lo Tartaro Meragliotta Patrizia, Lombardini Martina, Lorenzon Eleonora, Mainini Nicoletta, Massoud Michela, Materia Valeria, Mattera Raffaele, Mauro Isabella, Melani Federico, Meli Mariaclaudia, Messina Giovanni, Monticone Sonia, Moras Marzia, Negro Ilaria, Olzai Giorgio, Pancani Simone, Pandolfi Maria, Passariello Annalisa, Passarini Alice, Passone Eva, Pastorino Myriam, Pegoraro Veronica, Pennoni Serena, Perilongo Giorgio, Pozzessere Anna, Pruna Dario, Pusiol Anna, Putti Maria Caterina, Rabbone Ivana, Radicioni Maurizio, Renna Salvatore, Ricci Maria Luisa, Rimini Alessandro, Rivellini Sara, Rustioni Gianluca, Salvadori Sabrina, Santoiemma Valentina, Santoro Nicola, Schiavulli Michele, Sebellin Sofia, Sesta Michela, Soffiati Massimo, Sorbo Monica, Spanedda Giuseppina, Stangalini Valeria, Stasolla Salvatore, Tanzi Giorgia, Testa Tiziana, Teutonico Federica, Timpani Giuseppina, Toldo Irene, Trapani Sandra, Vaccari Roberto, Vecchi Marilena, Vento Giovanni, Veraldi Daniele, Villa Giovanna, Visintin Gianluca, Zambelloni Cesare, and Zellini Francesco

Subjects
thrombosis, stroke, children, pediatric, registry, thromboembolism, Pediatrics, RJ1-570
Published
2024
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2. The new Italian registry of infantile thrombosis (RITI): A reflection on its journey, challenges and pitfalls

Author

Maria Federica Pelizza, Matteo Martinato, Anna Rosati, Margherita Nosadini, Paola Saracco, Paola Giordano, Matteo Luciani, Laura Ilardi, Donatella Lasagni, Angelo Claudio Molinari, Rossana Bagna, Antonella Palmieri, Luca Antonio Ramenghi, Massimo Grassi, Mariella Magarotto, Federica Magnetti, Andrea Francavilla, Giuseppe Indolfi, Agnese Suppiej, Chiara Gentilomo, Roberta Restelli, Antonella Tufano, Daniela Tormene, Jacopo Norberto Pin, Clarissa Tona, Davide Meneghesso, Lidia Rota, Marta Conti, Giovanna Russo, Giulia Lorenzoni, Dario Gregori, Stefano Sartori, Paolo Simioni, Collaborators of the R.I.T.I. (Italian Registry of Infantile Thrombosis), Accorsi Patrizia, Aceto Gabriella, Agnoletti Gabriella, Agostini Manuela, Alfarano Angela, Altieri Elena, Amador Carolina, Antonelli Camilla, Arena Vittoria, Asta Francesca, Baggio Laura, Ballardini Elisa, Baracetti Margherita, Baraldi Eugenio, Barberis Laura, Barisone Elena, Basso Anne Letizia, Battajon Nadia, Bersani Iliana, Biddeci Giada, Biffanti Roberta, Bonardi Claudia Maria, Bonaudo Roberto, Boniver Clementina, Boscarol Gianluca, Bottino Roberto, Bravar Giulia, Brizzi Ilaria, Brolatti Noemi, Braguglia Annabella, Guaragni Brunetta, Bugin Samuela, Calvo Pier Luigi, Capasso Antonella, Capodiferro Donatella, Cappelleri Alessia, Cascarano Maria Teresa, Casellato Susanna, Casini Tommaso, Catarzi Serena, Cavaliere Elena, Cavicchiolo Maria Elena, Celestino Silvia, Celle Maria Elena, Centonze Nicola, Cerutti Alessia, Chakrokh Roksana, Offer Chiara, Chiodin Elisabetta, Chirico Gaetano, Chukhlantseva Natalia, Cifarelli Paola, Cinelli Giulia, Coinu Marisa, Colonna Clara, Comito Donatella, Corato Alessandra, Cordelli Duccio Maria, Crichiutti Giovanni, Cursio Ida, Dagri Arianna, De Maria Beatrice, Del Borrello Giovanni, Di Rienzo Francesca, Doglioni Nicoletta, Dolcemascolo Valentina, Dotta Andrea, Drigo Paola, Drimaco Pietro, Ellero Serena, Falcone Alessandra, Fantauzzi Ambra, Farinasso Daniela, Ferilli Michela, Festa Silvia, Fischer Maximilian, Foiadelli Thomas, Fotzi Ilaria, Francavilla Rosa, Freschi Paola, Gaffuri Marcella, Gallo Elena, Gamalero Lisa, Gandioli Claudia, Garuccio Sergio, Gentile Diletta, Ghionzoli Marco, Giliberti Paola, Greco Filippo, Guariento Chiara, Guidotti Isotta, Iodice Alessandro, Janes Augusta, Laghi Elena, Lampugnani Elisabetta, Lassandro Giuseppe, Laverda Anna Maria, Lazzerotti Alessandra, Lo Tartaro Meragliotta Patrizia, Lombardini Martina, Lorenzon Eleonora, Mainini Nicoletta, Massoud Michela, Materia Valeria, Mattera Raffaele, Mauro Isabella, Melani Federico, Meli Mariaclaudia, Messina Giovanni, Monticone Sonia, Moras Marzia, Negro Ilaria, Olzai Giorgio, Pancani Simone, Pandolfi Maria, Passariello Annalisa, Passarini Alice, Passone Eva, Pastorino Myriam, Pegoraro Veronica, Pennoni Serena, Perilongo Giorgio, Pozzessere Anna, Pruna Dario, Pusiol Anna, Putti Maria Caterina, Rabbone Ivana, Radicioni Maurizio, Renna Salvatore, Ricci Maria Luisa, Rimini Alessandro, Rivellini Sara, Rustioni Gianluca, Salvadori Sabrina, Santoiemma Valentina, Santoro Nicola, Schiavulli Michele, Sebellin Sofia, Sesta Michela, Soffiati Massimo, Sorbo Monica, Spanedda Giuseppina, Stangalini Valeria, Stasolla Salvatore, Tanzi Giorgia, Testa Tiziana, Teutonico Federica, Timpani Giuseppina, Toldo Irene, Trapani Sandra, Vaccari Roberto, Vecchi Marilena, Vento Giovanni, Veraldi Daniele, Villa Giovanna, Visintin Gianluca, Zambelloni Cesare, and Zellini Francesco

Subjects
thrombosis, stroke, children, pediatric, registry, thromboembolism, Pediatrics, RJ1-570
Abstract

IntroductionThrombotic events in neonates and children represent a rare although severe occurrence in view of the associated risk of mortality and sequelae. Quality evidence is limited in this field, and registry studies provide an essential base for research. The aim of this paper is to present the new Italian Registry of Infantile Thrombosis (RITI), set it into the scene of international thrombosis and stroke registries, and provide some insight on the challenges associated with registry management.MethodsWe present the detailed structure and content of the new RITI registry, a brief overview of its main data, and a reflection on its features, pitfalls and the main challenges related to its management.ResultsThe RITI, initially started in 2007 and officially re-launched in 2017 after structural modifications, is a non-interventional retrospective and prospective registry study collecting data on neonatal and pediatric patients (0–18 years) who experienced a systemic or cerebral thrombotic event in Italy. The RITI is managed by a multidisciplinary team with expertise in pediatric thrombosis, and participation is open to all Italian physicians, on a voluntary basis. The overall aim of the registry is to acquire new evidence to better characterize the population of children with thrombotic events and improve their management and outcome. 48 Italian pediatric and intensive care units are actively involved in the RITI, including 85 medical doctors from 16 Italian regions. A total of 1,001 neonates and children affected by cerebral or systemic thrombosis have been enrolled.DiscussionThe RITI is one of the largest available European registries of neonatal and pediatric thrombosis. National registries like the RITI represent a model for the study of rare conditions based on multidisciplinary and multicenter collaboration, aimed at overcoming the limitations due to small populations of patients, and creating a network of experts for patient referral and continuous education. Moreover, registry studies have a pivotal role in the research on pediatric thrombosis, due to the limited feasibility of high-quality studies. In our experience, the main critical stages, pitfalls and challenges in registry management include adequate registry designing, diffusion, data completeness and quality control.

Published
2023
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3. Recommendations for the management of acute immune thrombocytopenia in children. A Consensus Conference from the Italian Association of Pediatric Hematology and Oncology.

Author

Russo, Giovanna, Parodi, Emilia, Farruggia, Piero, Notarangelo, Lucia D., Perrotta, Silverio, Casale, Maddalena, Cesaro, Simone, Del Borrello, Giovanni, Del Vecchio, Giovanni C., Giona, Fiorina, Gorio, Chiara, Ladogana, Saverio, Lassandro, Giuseppe, Marzollo, Antonio, Maslak, Karolina, Miano, Maurizio, Nardi, Margherita, Palumbo, Giuseppe, Rossi, Francesca, and Spinelli, Marco

Published
2024
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4. Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC

Author

Gresele, Paolo, Orsini, Sara, Noris, Patrizia, Falcinelli, Emanuela, Alessi, Marie Christine, Bury, Loredana, Borhany, Munira, Santoro, Cristina, Glembotsky, Ana C., Cid, Ana Rosa, Tosetto, Alberto, De Candia, Erica, Fontana, Pierre, Guglielmini, Giuseppe, Pecci, Alessandro, Heller, Paula G., Rodorigo, Giuseppina, Lammle, Bernhard, Trinchero, Alice, Paolo, Radossi, Ferrari, Silvia, Rancitelli, Davide, Stolinski, Amy, Arulselvan, Abinaya, Lassandro, Giuseppe, Luceros, Analia Sanchez, Jandrot‐Perrus, Martine, Kunishima, Shinji, Rivera Pozo, José, Lordkipanidzé, Marie, Melazzini, Federica, Falaise, Céline, Casonato, Alessandra, Podda, Gianmarco, Kannan, Meganathan, Jurk, Kerstin, Sevivas, Teresa, Castaman, Giancarlo, Grandone, Elvira, Fiore, Mathieu, Zuniga, Pamela, Henskens, Yvonne, Miyazaki, Koji, Dupuis, Arnaud, Hayward, Catherine, Zaninetti, Carlo, Abid, Madiha, Ferrara, Grazia, Mazzucconi, Maria Gabriella, Tagariello, Giuseppe, James, Paula, Fabris, Fabrizio, Russo, Alexandra, Bermejo, Nuria, Napolitano, Mariasanta, Curnow, Jennifer, Vasiliki, Gkalea, Zieger, Barbara, Fedor, Marian, Chitlur, Meera, Lambert, Michele, Barcella, Luca, Cosmi, Benilde, Giordano, Paola, Porri, Claudia, Eker, Ibrahim, Morel‐Kopp, Marie‐Christine, Deckmyn, Hans, Frelinger, Andrew L., III, Harrison, Paul, Mezzano, Diego, and Mumford, Andrew D.

Published
2020
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5. Rituximab Unveils Hypogammaglobulinemia and Immunodeficiency in Children with Autoimmune Cytopenia

Author

Ottaviano, Giorgio, Marinoni, Maddalena, Graziani, Simona, Sibson, Keith, Barzaghi, Federica, Bertolini, Patrizia, Chini, Loredana, Corti, Paola, Cancrini, Caterina, D'Alba, Irene, Gabelli, Maria, Gallo, Vera, Giancotta, Carmela, Giordano, Paola, Lassandro, Giuseppe, Martire, Baldassare, Angarano, Rosa, Mastrodicasa, Elena, Bava, Cecilia, Miano, Maurizio, Naviglio, Samuele, Verzegnassi, Federico, Saracco, Paola, Trizzino, Antonino, Biondi, Andrea, Pignata, Claudio, and Moschese, Viviana

Published
2020
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7. Double-blind, placebo-controlled, randomized trial on low-dose azithromycin prophylaxis in patients with primary antibody deficiencies

Author

Milito, Cinzia, Pulvirenti, Federica, Cinetto, Francesco, Lougaris, Vassilios, Soresina, Annarosa, Pecoraro, Antonio, Vultaggio, Alessandra, Carrabba, Maria, Lassandro, Giuseppe, Plebani, Alessandro, Spadaro, Giuseppe, Matucci, Andrea, Fabio, Giovanna, Dellepiane, Rosa Maria, Martire, Baldassarre, Agostini, Carlo, Abeni, Damiano, Tabolli, Stefano, and Quinti, Isabella

Published
2019
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8. Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review

Author

Yu, Jacky K., Iorio, Alfonso, Edginton, Andrea N., Ahuja, Sanjay, Álvarez Román, Ma Teresa, Arrieta, Ma E., Arola, Mikko, Barillari, Giovanni, Balasa, Vinod, Belletrutti, Mark, Berrueco Moreno, Ruben, Beurrier, Philippe, Bidlingmaier, Cristoph, Blanchette, Victor, Blatny, Jan, Bonanad, Santiago, Brose, Kelsey, Brown, Deborah, Byant, Paulette C., Canaro, Mariana, Carvalho, Manuela, Catarino, Cristina, Chitlur, Meera, Cockrell, Erin, Chowdary, Pratima, Cnossen, Marjon, Collins, Peter, Coppens, Michial, Croteau, Stacy, Cultrera, Dorina, de Cristofaro, Raimundo, de Raucourt, Emmauelle, Desprez, Dominique, Dunn, Amy, El‐Ekiabi, Magda, Faganel Kotnik, Barbara, Fischer, Kathleen, Frotscher, Brigit, Garbiero, Susana, Garrido Ruiz, Raquel, Gill, Joan, Gomez del Castillo, Carmen, Gottstein, Saskia, Lassandro, Giuseppe, Giordano, Paola, Hart, Daniel, Hegemann, Inga, Hermans, Cedric, Hua, Baolai, Hwang, Nina, Jackson, Shannon, James, Paula, Katsarou, Olga, Kavakli, Kaan, Kempton, Christine, Kentouche, Karim, Khan, Osman, Kobelt, Rainer, Kruse‐Jarres, Rebecca, Laane, Edward, Larson, Eric, Lassila, Riitta, Lee, Adrienne, Poon, Man‐Chiu, Lissick, Jennifer, Langstrom, Satu, Mahlangu, Johnny, Makris, Michael, Marchesini, Emmanuela, Mateo, Jose, Marco Vera, Pacual, Martorell, Marta, Matsushita, Tadashi, McCrae, Simon, Mignot‐Castellano, Eva, Montcrieff, Caitlin, Maes, Philip, Mondelars, Veerle, Bekart, Marlies, Mora, Elena, Cristóbal Morales, Juan, Mourey, Guillaume, Bertrand, Marie Ann, Napolitano, Mariasanta, Siragusa, Sergio, Negrier, Claude, Neme, Daniela, Niinimaki, Ritta, Oldenburg, Johannes, Albert, Thilo, Ornstein, Deborah, Ozelo, Margarete, Panetta, John Carl, Neufeld, Ellis J., P'Ng, Stephanie, Peerlinck, Kathelijne, Pollio, Berardino, Pouplard, Claire, Gruel, Yves, Prezotti, Alessandra, Price, Vicky, Primacakti, Fitri, Puyade, Mathieu, Radossi, Paolo, Raffini, Leslie, Ragni, Margaret, Rangarajan, Savita, Reding, Mark T., Reid, Robin, Restrepo, Jose, Ramirez, Jose, Recht, Michael, Rodriguez Lopez, Manuel, Ruiz‐Sàez, Arlette, Saleh, Mahasen, Shapiro, Amy, Sharathkumar, Anjali, Selmeczi, Anna, Simpson, Mindy, Singleton, Tami, Cruz, Maria Sol, Soto, Veronica, Steele, MacGregor, Streif, Werner, Sun, Hao Wei, Ritchie, Bruce, Sun, Jing, Feng, Xiaqin, Suzuki, Takashi, Nagao, Asuza, Takemoto, Cliff, Tapp, Heather, Teitel, Jerry, Tinmouth, Alan, Thornburg, Courtney, Tosseto, Alberto, Turnstall, Oliver, Vezina, Catherine, Warren, Beth, Wheeler, Allison, Wilches Gutierrez, Juan D., Wu, John K.M., Wynn, Tung, Yang, Renchi, Young, Guy, Zanon, Ezio, and Zupan, Irena

Published
2019
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10. Long term use of eltrombopag in children with chronic immune thrombocytopenia: extended real life retrospective multicenter experience of the Italian Association of Pediatric Hematology and Oncology

Author

Giordano, Paola, primary, Lassandro, Giuseppe, additional, Barone, Angelica, additional, Cesaro, Simone, additional, Fotzi, Ilaria, additional, Giona, Fiorina, additional, Gorio, Chiara, additional, Maggio, Angela, additional, Miano, Maurizio, additional, Marzollo, Antonio, additional, Nardi, Margherita, additional, Pession, Andrea, additional, Ruggiero, Antonio, additional, Russo, Giovanna, additional, Saracco, Paola, additional, Spinelli, Marco, additional, Tolva, Alessandra, additional, Tornesello, Assunta, additional, Palladino, Valentina, additional, and Del Vecchio, Giovanni Carlo, additional

Published
2023
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11. Diagnosis and treatment of chronic synovitis in patients with haemophilia: consensus statements from the Italian Association of Haemophilia Centres

Author

Di Minno, Matteo Nicola Dario, Napolitano, Mariasanta, Giuffrida, Anna Chiara, Baldacci, Erminia, Carulli, Christian, Boccalandro, Elena, Bruno, Clarissa, Forneris, Eleonora, Ricca, Irene, Passeri, Walter, Martinelli, Marco, Rivolta, Gianna Franca, Solimeno, Luigi Piero, Martinoli, Carlo, Rocino, Angiola, Pasta, Gianluigi, Aru, Brigida, Balestri, Elena, Biasoli, Chiara, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppola, Antonio, Cultrera, Dorina, Daniele, Filomena, Ettorre, Cosimo Pietro, Giordano, Paola, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Luciani, Matteo, Malcangi, Giuseppe, Mancuso, Maria Elisa, Marchesini, Emanuela, Marino, Renato, Mazucconi, Maria Gabriella, Molinari, Angelo Claudio, Notarangelo, Lucia Dora, Pasca, Samantha, Quintavalle, Gabriele, Radossi, Paolo, Raso, Simona, Sabatino, Vincenzo, Santagostino, Elena, Santoro, Cristina, Scaturro, Dalila, Zanon, Ezio, Di Minno, Matteo Nicola Dario, Napolitano, Mariasanta, Giuffrida, Anna Chiara, Baldacci, Erminia, Carulli, Christian, Boccalandro, Elena, Bruno, Clarissa, Forneris, Eleonora, Ricca, Irene, Passeri, Walter, Martinelli, Marco, Rivolta, Gianna Franca, Solimeno, Luigi Piero, Martinoli, Carlo, Rocino, Angiola, Pasta, Gianluigi, Aru, Brigida, Balestri, Elena, Biasoli, Chiara, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppola, Antonio, Cultrera, Dorina, Daniele, Filomena, Ettorre, Cosimo Pietro, Giordano, Paola, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Luciani, Matteo, Malcangi, Giuseppe, Mancuso, Maria Elisa, Marchesini, Emanuela, Marino, Renato, Mazucconi, Maria Gabriella, Molinari, Angelo Claudio, Notarangelo, Lucia Dora, Pasca, Samantha, Quintavalle, Gabriele, Radossi, Paolo, Raso, Simona, Sabatino, Vincenzo, Santagostino, Elena, Santoro, Cristina, Scaturro, Dalila, Zanon, Ezio, and Matteo Nicola Dario Di Minno, Mariasanta Napolitano, Anna Chiara Giuffrida, Erminia Baldacci, Christian Carulli, Elena Boccalandro, Clarissa Bruno, Eleonora Forneris, Irene Ricca, Walter Passeri, Marco Martinelli, Gianna Franca Rivolta, Luigi Piero Solimeno, Carlo Martinoli, Angiola Rocino, Gianluigi Pasta, Dalila Scaturro

Subjects
haemophilia, haemophilic arthropathy, synovitis, Chronic Disease, Consensus, Hemophilia A, Humans, Italy, Synovitis, haemophilia, haemophilic arthropathy, synovitis, Hematology
Abstract

Although synovitis is recognized as a marker of joint disease activity, its periodic assessment is not included in routine clinical surveillance of patients with haemophilia (PwH). In order to evaluate the current knowledge and to identify controversial issues, a preliminary literature search by the Musculoskeletal Committee of the Italian Association of Haemophilia Centres (AICE) has been conducted. Statements have been established and sent to the Italian AICE members to collect their level of agreement or disagreement by a Delphi process. Thirty-seven consensus recommendations have been drafted. We found a general agreement on the indication to consider the presence of synovitis as a marker of joint disease activity in PwH. Accordingly, there was agreement on the indication to search for synovitis both in patients reporting joint pain and in asymptomatic ones, recognizing ultrasound as the most practical imaging technique to perform periodic joint screening. Interestingly, after detection of synovitis, there was agreement on the indication to modify the therapeutic approach, suggesting prophylaxis in patients treated on demand and tailoring treatment in patients already under prophylaxis. Whereas the need of an early consultation with a physiotherapist is recommended for PwH affected by chronic synovitis, the exact timing for an orthopaedic surgeon consultation is currently unknown.

Published
2021

14. “CHildren with Inherited Platelet disorders Surveillance” (CHIPS) retrospective and prospective observational cohort study by Italian Association of Pediatric Hematology and Oncology (AIEOP)

Author

Lassandro, Giuseppe, primary, Palladino, Valentina, additional, Faleschini, Michela, additional, Barone, Angelica, additional, Boscarol, Gianluca, additional, Cesaro, Simone, additional, Chiocca, Elena, additional, Farruggia, Piero, additional, Giona, Fiorina, additional, Gorio, Chiara, additional, Maggio, Angela, additional, Marinoni, Maddalena, additional, Marzollo, Antonio, additional, Palumbo, Giuseppe, additional, Russo, Giovanna, additional, Saracco, Paola, additional, Spinelli, Marco, additional, Verzegnassi, Federico, additional, Morga, Francesca, additional, Savoia, Anna, additional, and Giordano, Paola, additional

Published
2022
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15. Sex Hormone-Binding Globulin (SHBG) Reduction: The Alarm Bell for the Risk of Non-Alcoholic Fatty Liver Disease in Adolescents with Polycystic Ovary Syndrome

Author

Urbano, Flavia, primary, Chiarito, Mariangela, additional, Lattanzio, Crescenza, additional, Messa, Angela, additional, Ferrante, Marco, additional, Francavilla, Mariantonietta, additional, Mehmeti, Irsida, additional, Lassandro, Giuseppe, additional, Giordano, Paola, additional, and Faienza, Maria, additional

Published
2022
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18. Pain assessment and management in Italian Haemophilia Centres

Author

Di Minno, Matteo N D, Santoro, Cristina, Corcione, Antonio, Di Minno, Giovanni, Martinelli, Marco, Mancuso, Maria E, Acone, Benedetto, Molinari, Angelo C, Passeri, Emilio V, Rocino, Angiola, Santoro, Rita C, Tagliaferri, Annarita, Mattia, Consalvo, Agostini, Paola, Andreoli, Ernesto, Ambaglio, Chiara, Arancio, Fabiola, Aru, Brigida, Baldacci, Erminia, Belfiore, Antonella, Bernasconi, Sayla, Biasoli, Chiara, Borchiellini, Alessandra, Brunetti, Gregorio, Cerbone, Annamaria, Caimi, Teresa, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppetelli, Ugo, Costanzi, Matteo, Cultrera, Dorina, De Cristofaro, Raimondo, Delios, Grazia, Di Gennaro, Leonardo, Di Gregorio, Patrizia, Ettorre, Cosimo Pietro, Fasulo, Rosamaria, Feola, Giulio, Ferretti, Antonietta, Franchini, Massimo, Frizziero, Antonio, Galletti, Lisa, Giuffrida, Gaetano, Giuffrida, Annachiara, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Lione, Aurora, Lombardo, Rita, Luciani, Matteo, Macchi, Silvia, Maestrini, Giacomo, Malcangi, Giuseppe, Malizia, Raniero, Margaglione, Maurizio, Marietta, Marco, Marino, Renato, Massoud, Michela, Napolitano, Mariasanta, Nichele, Ilaria, Notarangelo, Lucia Dora, Pagano, Cinzia, Pasta, Gianluigi, Pollio, Berardino, Quintavalle, Gabriele, Ranalli, Paola, Raso, Simona, Ricca, Irene, Schiavoni, Mario, Schiavulli, Michele, Sottilotta, Gianluca, Todisco, Angela, Zanon, Ezio, Di Minno, Matteo N D, Santoro, Cristina, Corcione, Antonio, Di Minno, Giovanni, Martinelli, Marco, Mancuso, Maria E, Acone, Benedetto, Molinari, Angelo C, Passeri, Emilio V, Rocino, Angiola, Santoro, Rita C, Tagliaferri, Annarita, Mattia, Consalvo, Agostini, Paola, Andreoli, Ernesto, Ambaglio, Chiara, Arancio, Fabiola, Aru, Brigida, Baldacci, Erminia, Belfiore, Antonella, Bernasconi, Sayla, Biasoli, Chiara, Borchiellini, Alessandra, Brunetti, Gregorio, Cerbone, Annamaria, Caimi, Teresa, Cantori, Isabella, Coluccia, Antonella, Contino, Laura, Coppetelli, Ugo, Costanzi, Matteo, Cultrera, Dorina, De Cristofaro, Raimondo, Delios, Grazia, Di Gennaro, Leonardo, Di Gregorio, Patrizia, Ettorre, Cosimo Pietro, Fasulo, Rosamaria, Feola, Giulio, Ferretti, Antonietta, Franchini, Massimo, Frizziero, Antonio, Galletti, Lisa, Giuffrida, Gaetano, Giuffrida, Annachiara, Iannaccaro, Piergiorgio, Lassandro, Giuseppe, Linari, Silvia, Lione, Aurora, Lombardo, Rita, Luciani, Matteo, Macchi, Silvia, Maestrini, Giacomo, Malcangi, Giuseppe, Malizia, Raniero, Margaglione, Maurizio, Marietta, Marco, Marino, Renato, Massoud, Michela, Napolitano, Mariasanta, Nichele, Ilaria, Notarangelo, Lucia Dora, Pagano, Cinzia, Pasta, Gianluigi, Pollio, Berardino, Quintavalle, Gabriele, Ranalli, Paola, Raso, Simona, Ricca, Irene, Schiavoni, Mario, Schiavulli, Michele, Sottilotta, Gianluca, Todisco, Angela, and Zanon, Ezio

Subjects
Factor IX, Italy, Humans, Pain Management, pain heamophilia, Hemophilia A, blood coagulation disorders, haemophilia, pain perception, pain management, surveys, Haemostasis and Thrombosis, Pain Measurement
Abstract

BACKGROUND: Although the widespread use of factor VIII/IX replacement therapy has significantly reduced the severity of arthropathy in persons with haemophilia (PWH), some develop degenerative joint changes, associated with significant pain. The aim of this survey was to investigate the management and perception of pain among Italian physicians who treat PWH. MATERIALS AND METHODS: Between September and October 2017, a questionnaire was distributed to 35 Italian haemophilia treatment centres (60 physicians). RESULTS: Fifty-three haemophilia specialists completed the survey. We found that there was good agreement (98.1%) on the need to investigate pain at each clinical visit, but there was heterogeneity in the opinions of haemophilia specialists with regards to the availability of validated guidelines (35.8%) and whether pain specialists should be a part of the comprehensive care team in daily clinical practice (58.5%). Haemophilia specialists also agreed pain should be evaluated using a rating scale validated in PWH (88.7%). Pain was mainly managed by the haemophilia specialists themselves, supported by a physiatrist and physiotherapist, while a pain specialist was only involved in 26.4% of cases. The combination of paracetamol with tramadol or codeine was the most common first-line treatment, while cyclo-oxygenase-2 inhibitors, non-steroidal anti-inflammatory drugs, and opioids were less commonly used. DISCUSSION: There are some unmet needs in Italy regarding pain management for PWH and the management of pain in these patients by haemophilia specialists. There is a lack of evidence-based guidelines for these specialists to use, as well as a reluctance to involve pain specialists. The lack of spontaneous reporting of pain by PWH, despite using pain relief, highlights the need for clinicians to actively ask patients about any pain they may be experiencing.

Published
2021

19. Out-of-Season Epidemic of Respiratory Syncytial Virus during the COVID-19 Pandemic: The High Burden of Child Hospitalization in an Academic Hospital in Southern Italy in 2021

Author

Loconsole, Daniela, primary, Centrone, Francesca, additional, Rizzo, Caterina, additional, Caselli, Désirée, additional, Orlandi, Azzurra, additional, Cardinale, Fabio, additional, Serio, Cristina, additional, Giordano, Paola, additional, Lassandro, Giuseppe, additional, Milella, Leonardo, additional, Ficarella, Maria Teresa, additional, Baldassarre, Maria Elisabetta, additional, Laforgia, Nicola, additional, and Chironna, Maria, additional

Published
2022
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20. Promoting physical activity in people with haemophilia: the MEMO (Movement for persons with haEMOphilia) expert consensus project

Author

Biasoli, Chiara, Baldacci, Erminia, Coppola, Antonio, De Cristofaro, Raimondo, Di Minno, Matteo N D, Lassandro, Giuseppe, Linari, Silvia, Mancuso, Maria E, Napolitano, Mariasanta, Pasta, Gianluigi, Rocino, Angiola, Biasoli, Chiara, Baldacci, Erminia, Coppola, Antonio, De Cristofaro, Raimondo, Di Minno, Matteo N D, Lassandro, Giuseppe, Linari, Silvia, Mancuso, Maria E, Napolitano, Mariasanta, Pasta, Gianluigi, and Rocino, Angiola

Subjects
Consensus, recommendations, Quality of Life, haemophilia, physical activity, Humans, Prospective Studies, sport, Hemophilia A, Exercise, Haemostasis and Thrombosis
Abstract

Regular physical activity can increase joint stability and function, reduce the risk of injury, and improve quality of life of people with haemophilia (PwH). However, a recent review of the literature shows that appropriate physical activity and sport are not always promoted enough in the overall management of PwH. A group of Italian experts in haemophilia care undertook a consensus procedure to provide practical guidance on when and how to recommend physical exercise programmes to PwH in clinical practice. Three main topics were identified -haemophilia and its impact on movement, physical activity recommendations for PwH, and choice and management of sports activity in PwH- and ten statements were formulated. A modified Delphi approach was used to reach a consensus. The group also created practical tools proposing different physical activities and frequencies for different age groups, the Movement Pyramids, to be shared and discussed with patients and caregivers. In conclusion, in the opinion of the working group, physical activity can be considered as a low-price intervention that can prevent/reduce the occurrence of chronic diseases and should be further encouraged in PwH to obtain multiple physical and psychological benefits. Future research should include prospective studies focusing on participation in sports, specific risk exposure and clinical outcomes.

Published
2021

26. Association of Immune Thrombocytopenia and Coeliac Disease in Children (Retrospective Case Control Study)

Author

Guarina, Angela, primary, Marinoni, Maddalena, additional, Lassandro, Giuseppe, additional, Saracco, Paola, additional, Perrotta, Silverio, additional, Facchini, Elena, additional, Notarangelo, Lucia Dora, additional, Russo, Giovanna, additional, Giordano, Paola, additional, Romano, Francesca, additional, Bertoni, Elisa, additional, Gorio, Chiara, additional, Boscarol, Gianluca, additional, Motta, Milena, additional, Spinelli, Marco, additional, Barone, Angelica, additional, Zecca, Marco, additional, Compagno, Francesca, additional, Ladogana, Saverio, additional, Maggio, Angela, additional, Miano, Maurizio, additional, Dell’orso, Gianluca, additional, Chiocca, Elena, additional, Fotzi, Ilaria, additional, Petrone, Angela, additional, Tornesello, Assunta, additional, D’alba, Irene, additional, Salvatore, Silvia, additional, Casale, Maddalena, additional, Puccio, Giuseppe, additional, Ramenghi, Ugo, additional, and Farruggia, Piero, additional

Published
2021
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27. Association of Immune Thrombocytopenia and Inflammatory Bowel Disease in Children

Author

Guarina, Angela, primary, Barone, Angelica, additional, Tornesello, Assunta, additional, Marinoni, Maddalena, additional, Lassandro, Giuseppe, additional, Giordano, Paola, additional, Motta, Milena, additional, Spinelli, Marco, additional, Fontanili, Ilaria, additional, Giona, Fiorina, additional, Menna, Francesco, additional, Chiocca, Elena, additional, Fotzi, Ilaria, additional, Petrone, Angelamaria, additional, Graziano, Francesco, additional, Saracco, Paola, additional, Puccio, Giuseppe, additional, Citrano, Michele, additional, Russo, Giovanna, additional, and Farruggia, Piero, additional

Published
2021
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31. ABO Blood Group and Inhibitor Risk in Severe Hemophilia A Patients: A Study from the Italian Association of Hemophilia Centers

Author

Franchini, Massimo, additional, Coppola, Antonio, additional, Santoro, Cristina, additional, De Cristofaro, Raimondo, additional, Barillari, Giovanni, additional, Giordano, Paola, additional, Gresele, Paolo, additional, Lassandro, Giuseppe, additional, Napolitano, Mariasanta, additional, Lucchini, Giuseppe, additional, Luciani, Matteo, additional, Ferretti, Antonietta, additional, Baldacci, Erminia, additional, Riccardi, Federica, additional, Santoro, Rita Carlotta, additional, Pasca, Samantha, additional, Zanon, Ezio, additional, and Tagliaferri, Annarita, additional

Published
2021
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32. Covid-19 and Children with Immune Thrombocytopenia: emerging issues

Author

Lassandro, Giuseppe, Palladino, Valentina, Palmieri, Viviana Valeria, Amoruso, Anna, Del Vecchio, Giovanni Carlo, and Giordano, Paola

Subjects
immune thrombocytopenia, children, lcsh:RC633-647.5, lcsh:Diseases of the blood and blood-forming organs, Covid-19, Letter to the Editor
Abstract

Letter to Editor

Published
2020

33. Atypical Autoimmune Neutropenia: Data from The Italian Neutropenia Registry

Author

Fioredda, Francesca, Farruggia, Piero, Rotulo, Andrea, Pillon, Marta, Trizzino, Angela, Notarangelo, Lucia Dora, Luti, Laura, Lanza, Tiziana, Lanciotti, Marina, Isabella, Ceccherini, Alice, Grossi, Porretti, Laura, Matrodicasa, Elena, Barone, Angelica, Russo, Giovanna, Bonanomi, Sonia, Boscarol, Gianluca, Finocchi, Andrea, Veltroni, Marinella, Ramenghi, Ugo, Onofrillo, Daniela, Verzegnassi, Federico, Martire, Baldo, Ghilardi, Roberta, Lassandro, Giuseppe, La Dogana, Saverio, Marra, Nicoletta, PAOLA TERRANOVA, Zanardi, Sabrina, Dufour, Carlo, and Miano, Maurizio

Published
2020

34. Fatigue perception in a cohort of children with chronic immune thrombocytopenia and their caregivers using the PedsQL MFS: Real‐life multicenter experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

Author

Lassandro, Giuseppe, primary, Palmieri, Viviana Valeria, additional, Barone, Angelica, additional, Farruggia, Piero, additional, Giona, Fiorina, additional, Licciardello, Maria, additional, Marinoni, Maddalena, additional, Marzollo, Antonio, additional, Notarangelo, Lucia Dora, additional, Palumbo, Giuseppe, additional, Ramenghi, Ugo, additional, Russo, Giovanna, additional, Saracco, Paola, additional, Spinelli, Marco, additional, Tolva, Alessandra, additional, Tornesello, Assunta, additional, Palladino, Valentina, additional, Noviello, Domenico, additional, and Giordano, Paola, additional

Published
2020
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37. Substrate reduction therapy with Miglustat in pediatric patients with GM1 type 2 gangliosidosis delays neurological involvement: A multicenter experience

Author

Fischetto, Rita, primary, Palladino, Valentina, additional, Mancardi, Maria M., additional, Giacomini, Thea, additional, Palladino, Stefano, additional, Gaeta, Alberto, additional, Di Rocco, Maja, additional, Zampini, Lucia, additional, Lassandro, Giuseppe, additional, Favia, Vito, additional, Tripaldi, Maria E., additional, Strisciuglio, Pietro, additional, Romano, Alfonso, additional, Severino, Mariasavina, additional, Morrone, Amelia, additional, and Giordano, Paola, additional

Published
2020
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42. Use of Eltrombopag in Children With Chronic Immune Thrombocytopenia (ITP): A Real Life Retrospective Multicenter Experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

Author

Giordano, Paola, primary, Lassandro, Giuseppe, additional, Barone, Angelica, additional, Cesaro, Simone, additional, Fotzi, Ilaria, additional, Giona, Fiorina, additional, Ladogana, Saverio, additional, Miano, Maurizio, additional, Marzollo, Antonio, additional, Nardi, Margherita, additional, Notarangelo, Lucia Dora, additional, Pession, Andrea, additional, Ruggiero, Antonio, additional, Russo, Giovanna, additional, Saracco, Paola, additional, Spinelli, Marco, additional, Tolva, Alessandra, additional, Tornesello, Assunta, additional, Palladino, Valentina, additional, and Del Vecchio, Giovanni Carlo, additional

Published
2020
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43. Serum Vitamin D Levels in Children with Immune Thrombocytopenia

Author

Lassandro, Giuseppe, primary, Carriero, Francesco, additional, Palmieri, Viviana, additional, Palladino, Valentina, additional, Amoruso, Anna, additional, Gallone, Maria Filomena, additional, Del Vecchio, Giovanni C., additional, Tafuri, Silvio, additional, Russo, Giovanna, additional, Valente, Federica, additional, and Giordano, Paola, additional

Published
2020
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44. Perceived well-being and mental health in haemophilia

Author

Negri, Luca, primary, Buzzi, Andrea, additional, Aru, Anna Brigida, additional, Cannavò, Antonino, additional, Castegnaro, Claudio, additional, Fasulo, Maria Rosaria, additional, Lassandro, Giuseppe, additional, Rocino, Angiola, additional, Santoro, Cristina, additional, Sottilotta, Gianluca, additional, Giordano, Paola, additional, Mazzucconi, Maria Gabriella, additional, Mura, Rosamaria, additional, Peyvandi, Flora, additional, and Delle Fave, Antonella, additional

Published
2020
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46. Double-Blind, Placebo-Controlled Randomized Trial on Low Dose Azithromycin Prophilaxis in Primary Antibody Deficiencies

Author

Milito, Cinzia, Pulvirenti, Federica, Cinetto, Francesco, Lougaris, Vassilios, Soresina, Annarosa, Pecoraro, Antonio, Vultaggio, Alessandra, Carrabba, Maria, Lassandro, Giuseppe, Plebani, Alessandro, Spadaro, Giuseppe, Matucci, Andrea, Fabio, Giovanna, Dellepiane, Rosa Maria, Martire, Baldassarre, Agostini, Carlo, Abeni, Damiano, Tabolli, Stefano, and Quinti, Isabella

Subjects
Primary Antibody DefectsAzithromycinAntibiotic ProphylaxisRespiratory exacerbationCOPD, Respiratory exacerbation, Antibiotic Prophylaxis, Azithromycin, COPD, Primary Antibody Defects
Published
2019

47. Association of Immune Thrombocytopenia and Celiac Disease in Children: A Retrospective Case Control Study.

Author

Guarina, Angela, Marinoni, Maddalena, Lassandro, Giuseppe, Saracco, Paola, Perrotta, Silverio, Facchini, Elena, Notarangelo, Lucia Dora, Russo, Giovanna, Giordano, Paola, Romano, Francesca, Bertoni, Elisa, Gorio, Chiara, Boscarol, Gianluca, Motta, Milena, Spinelli, Marco, Barone, Angelica, Zecca, Marco, Compagno, Francesca, Ladogana, Saverio, and Maggio, Angela

Subjects
CELIAC disease complications, RESEARCH, THROMBOPENIC purpura, RETROSPECTIVE studies, CASE-control method, MEDICAL cooperation, DESCRIPTIVE statistics, DISEASE risk factors, CHILDREN
Abstract

Copyright of Turkish Journal of Hematology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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