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War, geopolitical instability, and natural disasters have contributed to enormous unmet mental health needs in the Middle East and North Africa. Jordan is a middle-income country that needs internal and international stakeholder engagement and support to effectively provide mental health services to its citizens and to the millions of immigrants and refugees who reside there. This column presents a snapshot of the state of mental health care in Jordan and outlines areas for future investment. Potentially high-yield areas for development include digital health technology, integrated care, and youth-focused interventions. [ABSTRACT FROM AUTHOR]

Thirty years of intervention research on the effects of reading comprehension strategies for students with learning disabilities was reviewed in this quantitative synthesis. Specifically, researchers targeted studies that contained self-regulated learning components. A systematic search yielded 18 studies from nine research journals that met specified inclusion criteria. Studies were evaluated for methodological quality and to identify types of instructional and self-regulation components within interventions. Large effect sizes were found immediately after instruction and after a time delay, suggesting that instruction in reading comprehension strategies that contain self-regulation components may have a long lasting impact on student performance. Implications for research and practice are discussed.

This study analyzed three types of visual representations (graphs, maps, & graphic organizers) in the most widely used eighth-grade U.S. History textbooks. The analyses included how each visual was constructed and used within the context of text narrative. Purposeful sampling techniques were used to select a representative sample of varied topics addressed in all textbooks. Findings indicate that graphic organizers and maps were used more frequently across texts than graphs. Although most visuals were constructed well, few texts explicitly or implicitly connected the visuals to texts' narrative, which has literacy implications for students' comprehension. Other strengths and areas of need are identified. For areas of need, implications for pedagogies to enhance students' comprehension of and connections with the visuals themselves are described.

Introduction: With the goal to maximize intake of high-fermentable diet needed to meet energy needs during weaning period, calves are at risk for ruminal acidosis. Using the calves from previously established model of feed-induced, ruminal acidosis in young calves, we aimed to investigate the changes in rumen epimural transcriptome and its microbial metatranscriptome at weaning (8- week) and post-weaning (17-week) in canulated (first occurred at 3 weeks of age) Holstein bull calves with feed-induced subacute ruminal acidosis. Methods: Eight bull calves were randomly assigned to acidosis-inducing diet (Treated, n = 4; pelleted, 42.7% starch, 15.1% neutral detergent fiber [NDF], and 57.8% nonfiber carbohydrates), while texturized starter was fed as a control (Control, n = 4; 35.3% starch, 25.3% NDF, and 48.1% nonfiber carbohydrates) starting at 1 week through 17 weeks. Calves fed acidosis-inducing diet showed significantly less (p < 0.01) body weight over the course of the experiment, in addition to lower ruminal pH (p < 0.01) compared to the control group. Rumen epithelial (RE) tissues were collected at both 8 weeks (via biopsy) and 17 weeks (via euthanasia) and followed for whole transcriptome RNA sequencing analysis. Differentially expressed genes (DEGs) analysis was done using cufflinks2 (foldchange ≥2 and p < 0.05) between treated and control groups at 8-week of age, and between 8- and 17-week for the treated group. Results: At 8-week of age, DEGs between treatment groups showed an enrichment of genes related to the response to lipopolysaccharide (LPS) (p < 0.005). The impact of prolonged, feed-induced acidosis was reflected by the decreased expression (p < 0.005) in genes involved in cell proliferation related pathways in the RE at 17- week of age in the treated group. Unique sets of discriminant microbial taxa were identified between 8-and 17-week calves in the treated group and the treatment groups at 8-week, indicating that active microbial community changes in the RE are an integral part of the ruminal acidosis development and progression. [ABSTRACT FROM AUTHOR]

Refugee populations face disproportionately high risk for mental health challenges because of their exposure to geopolitical conflict, persecution, violence, and human rights violations. Dedicated, sustained psychological services are scarce in refugee contexts. Access to mental health treatment is limited by stigma and discrimination, linguistic and cultural barriers, and lack of privacy and confidentiality. Digital health approaches can increase access to mental health services in refugee contexts where need is high, mobile device infrastructure is common, and digital options may transcend contextual barriers. Tailored digital mental health interventions that may overcome barriers to mental health treatment among refugee populations are outlined. [ABSTRACT FROM AUTHOR]

Simple Summary: Postweaning diarrhea due to pathogenic Escherichia coli is a common issue in swine production. Specific strains of Bacillus subtilis have been shown to reduce the incidence and severity of diarrhea and thereby improve the growth of nursery pigs. The current study aims to demonstrate the effect of B. subtilis supplementation of two strains selected to reduce the effects of pathogenic E. coli to nursery pig diets on growth performance, blood biochemicals, fecal metabolites, and microbiome. B. subtilis supplementation to nursery diets at 1.875 × 105 CFU/g diet improved early postweaning growth performance, increased blood glucose levels, and fecal short-chain fatty acid production, which is beneficial for the gut health and development for nursery pigs. But a higher dose of B. subtilis did not affect pig growth and fecal short-chain fatty acid production. These results suggest that B. subtilis supplementation to nursery pig diets at 1.875 × 105 CFU/g diet is beneficial for growth and gut health, whereas a higher dose of the probiotic may not be as effective as the recommended level. This experiment was conducted to evaluate the effects of dietary supplementation level of a two-strain Bacillus subtilis probiotic on growth performance, blood parameters, fecal metabolites, and microbiome in nursery pigs. A total of 54 weaned piglets were allotted to three treatments in three replicate pens with six pigs/pen for a 28 d feeding trial. The treatments were as follows: control: no probiotic supplementation; Pro1x: B. subtilis supplementation at 1.875 × 105 CFU/g diet; and Pro10x: B. subtilis supplementation at 1.875 × 106 CFU/g diet. Body weight at d 14 postweaning (p = 0.06) and average daily gain for d 0 to 14 postweaning (p < 0.05) were greater in the Pro1x treatment than in the other treatments. Blood glucose levels were greater in both probiotic treatments than in the control treatment at d 14 postweaning (p < 0.05). In the fecal short-chain fatty acid (SCFA) concentrations, the butyrate concentrations were greater in the Pro1x treatment than in the other treatments (p < 0.05), and the acetate, propionate, and total SCFA concentrations were greater in the Pro1x treatment than in the Pro10x treatment (p < 0.05). The beta diversity of fecal microbiome composition at d 14 postweaning based on Unweighted Unifrac analysis was dissimilar between the Pro1x and Pro10x treatments (p < 0.05). In conclusion, dietary B. subtilis supplementation of two strains selected to reduce effects of pathogenic Escherichia coli to nursery diets at 1.875 × 105 CFU/g diet improved the growth rate in the early postweaning period, increased fecal SCFA concentrations and altered the fecal microbial community composition. A higher dose of B. subtilis did not improve the performance parameters over those of the control piglets. [ABSTRACT FROM AUTHOR]