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37 results on '"Larkin, Genevieve"'

1. Executive summary: British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Author

Price, Elizabeth J, primary, Benjamin, Stuart, additional, Bombardieri, Michele, additional, Bowman, Simon, additional, Carty, Sara, additional, Ciurtin, Coziana, additional, Crampton, Bridget, additional, Dawson, Annabel, additional, Fisher, Benjamin A, additional, Giles, Ian, additional, Glennon, Peter, additional, Gupta, Monica, additional, Hackett, Katie L, additional, Larkin, Genevieve, additional, Ng, Wan-Fai, additional, Ramanan, Athimalaipet V, additional, Rassam, Saad, additional, Rauz, Saaeha, additional, Smith, Guy, additional, Sutcliffe, Nurhan, additional, Tappuni, Anwar, additional, and Walsh, Stephen B, additional

Published
2024
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2. British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease

Author

Price, Elizabeth J, primary, Benjamin, Stuart, additional, Bombardieri, Michele, additional, Bowman, Simon, additional, Carty, Sara, additional, Ciurtin, Coziana, additional, Crampton, Bridget, additional, Dawson, Annabel, additional, Fisher, Benjamin A, additional, Giles, Ian, additional, Glennon, Peter, additional, Gupta, Monica, additional, Hackett, Katie L, additional, Larkin, Genevieve, additional, Ng, Wan-Fai, additional, Ramanan, Athimalaipet V, additional, Rassam, Saad, additional, Rauz, Saaeha, additional, Smith, Guy, additional, Sutcliffe, Nurhan, additional, Tappuni, Anwar, additional, and Walsh, Stephen B, additional

Published
2024
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3. Association of Dry Eye Tests With Extraocular Signs Among 3514 Participants in the Sjögren's Syndrome International Registry

Author

Bunya, Vatinee Y, Bhosai, Satasuk Joy, Heidenreich, Ana Maria, Kitagawa, Kazuko, Larkin, Genevieve B, Lietman, Thomas M, Gaynor, Bruce D, Akpek, Esen K, Massaro-Giordano, Mina, Srinivasan, M, Porco, Travis C, Whitcher, John P, Shiboski, Stephen C, Criswell, Lindsey A, Shiboski, Caroline H, and Group, Sjögren's International Collaborative Clinical Alliance Study

Subjects
Biomedical and Clinical Sciences, Ophthalmology and Optometry, Digestive Diseases, Prevention, Eye Disease and Disorders of Vision, Clinical Research, Eye, Cross-Sectional Studies, Dry Eye Syndromes, Female, Global Health, Humans, Incidence, Male, Registries, Severity of Illness Index, Sjogren's Syndrome, Tears, Young Adult, Sjögren's International Collaborative Clinical Alliance (SICCA) Study Group, Clinical Sciences, Opthalmology and Optometry, Public Health and Health Services, Ophthalmology & Optometry, Ophthalmology and optometry
Abstract

PurposeTo identify a screening strategy for dry eye patients with a high likelihood of having Sjogren syndrome (SS) through the evaluation of the association of ocular surface tests with the extraocular signs used for the diagnosis of SS.DesignMulticenter cross-sectional study.MethodsThe Sjogren's International Clinical Collaborative Alliance (SICCA) registry enrolled 3514 participants with SS or possible SS from 9 international academic sites. Ocular surface evaluation included Schirmer I testing, tear breakup time (TBUT), and staining of the cornea (0-6 points) and conjunctiva (0-6 points). Multivariate logistic regression analysis was performed to identify predictive factors for (1) histopathologic changes on labial salivary gland (LSG) biopsies (positive = focus score of ≥1 focus/4 mm2) and (2) positive anti-SSA/B serology.ResultsThe adjusted odds of having a positive LSG biopsy were significantly higher among those with an abnormal Schirmer I test (adjusted OR = 1.26, 95% CI 1.05-1.51, P = .014) and positive conjunctival staining (for each additional unit of staining 1.46; 95% CI 1.39-1.53, P < .001) or corneal staining (for each additional unit of staining 1.14; 95% CI 1.08-1.21, P < .001). The odds of having a positive serology were significantly higher among those with an abnormal Schirmer I test (adjusted OR = 1.3; 95% CI 1.09-1.54, P = .004) and conjunctival staining (adjusted OR = 1.51; 95% CI 1.43-1.58, P < .001).ConclusionsIn addition to corneal staining, which was associated with a higher likelihood of having a positive LSG biopsy, conjunctival staining and abnormal Schirmer I testing are of critical importance to include when screening dry eye patients for possible SS, as they were associated with a higher likelihood of having a positive LSG biopsy and serology.

Published
2016

7. The management of Sjögren’s syndrome: British Society for Rheumatology guideline scope

Author

Price, Elizabeth, primary, Allen, Alexander, additional, Rauz, Saaeha, additional, Tappuni, Anwar, additional, Sutcliffe, Nurhan, additional, Bombardieri, Michele, additional, Carty, Sara, additional, Ciurtin, Coziana, additional, Crampton, Bridget, additional, Duncalfe, Lisa, additional, Fisher, Benjamin, additional, Glennon, Peter, additional, Hackett, Katie L, additional, Larkin, Genevieve, additional, Ng, Wan-Fai, additional, Ramanan, Athimalaipet V, additional, Rassam, Saad, additional, Walsh, Stephen B, additional, and Bowman, Simon, additional

Published
2021
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17. A comparison of two scoring methods for the King's sarcoidosis questionnaire

Author

Sinha, Aish, primary, Bajwah, Sabrina, additional, Gosker, Harry, additional, Siegert, Richard, additional, Creamer, Daniel, additional, Larkin, Genevieve, additional, Maher, Toby, additional, Renzoni, Elisabetta, additional, Wells, Athol, additional, Higginson, Irene, additional, Birring, Surinder, additional, and Patel, Amit, additional

Published
2015
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20. A simplified quantitative method for assessing keratoconjunctivitis sicca from the Sjögren's Syndrome International Registry

Author

Whitcher, John P, Shiboski, Caroline H, Shiboski, Stephen C, Heidenreich, Ana Maria, Kitagawa, Kazuko, Zhang, Shunhua, Hamann, Steffen, Larkin, Genevieve, McNamara, Nancy A, Greenspan, John S, Daniels, Troy E, Whitcher, John P, Shiboski, Caroline H, Shiboski, Stephen C, Heidenreich, Ana Maria, Kitagawa, Kazuko, Zhang, Shunhua, Hamann, Steffen, Larkin, Genevieve, McNamara, Nancy A, Greenspan, John S, and Daniels, Troy E

Abstract

To describe, apply, and test a new ocular grading system for assessing keratoconjunctivitis sicca (KCS) using lissamine green and fluorescein.

Published
2010

22. Correlation between ultrasound imaging of major salivary glands and histopathological findings of labial gland biopsy samples in Sjogren's syndrome

Author

Ali, Shabnum, primary, Brown, Jackie, additional, Ngu, Rose, additional, Daniels, Troy, additional, Greenspan, John, additional, Odell, Edward, additional, Shirlaw, Penelope J, additional, Gohil, Kuldipsinh G, additional, Kirkham, Bruce, additional, Larkin, Genevieve, additional, and Challacombe, Stephen J, additional

Published
2013
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25. Minerva

Author

Patel, Nishal, primary, Larkin, Genevieve, additional, and Stamford, Miles, additional

Published
2007
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27. Authors’ reply

Author

Flaxel, Christina J, primary, Larkin, Genevieve B, additional, and Leaver, Peter K, additional

Published
1999
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30. Reply

Author

Broadway, David C., primary, Larkin, Genevieve B., additional, Leaver, Peter K., additional, and Flaxel, Christina J., additional

Published
1998
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31. Ofloxacin Monotherapy for the Primary Treatment of Microbial Keratitis

Author

Pavesio, Carlos, primary, Morlet, Nigel, additional, Allan, Bruce, additional, El Kassaby, Hosam, additional, DeCock, Romain, additional, Butcher, Jeremy, additional, Baer, Roger, additional, Broadway, David, additional, Charles, Stephen J., additional, Duguid, Graham, additional, Heyworth, Peter, additional, Jenkins, Chris, additional, Larkin, Genevieve, additional, Lloyd, Ian C., additional, McNaught, Andrew, additional, Dart, John, additional, Tullo, Andrew, additional, Ficker, Linda, additional, Minassian, Darwin, additional, Matheson, Melville, additional, and Johnson, Alan P., additional

Published
1997
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36. Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis.

Author

Lightman, Susan, Young, Stephanie, Larkin, Genevieve, and Branley, Michael

Subjects
TRIAMCINOLONE, RETINAL degeneration treatment, DRUG efficacy
Abstract

ABSTRACT Purpose: To report the safety and efficacy of intravitreal triamcinolone in the treatment of inflammatory cystoid macular oedema (CMO) in six patients who were resistant to other forms of therapy. Methods: An open-label unmasked prospective non- randomized pilot study of six patients with idiopathic uveitis and visually significant macular oedema, resistant to periocular and/or systemic corticosteroid treatment, was carried out. Baseline examination and investigations were performed, including fundus fluorescein angiography, and the patients were given a single intravitreal injection of triamcinolone (4 mg/0.1 mL). The primary outcome measure was angiographic resolution of CMO. Patients were reviewed at intervals of 2–4 weeks for 12 months. Results: A single intravitreal injection of triamcinolone induced clinical and angiographic resolution of inflammatory macular oedema in all patients for varying periods of time up to 6 months. Five patients experienced increased intraocular pressure to 30 mmHg or greater which required treatment. Two patients developed posterior subcapsular cataract. Conclusion: One injection of intravitreal triamcinolone was an effective short-term treatment for resistant CMO in uveitis. As with steroids given by other routes, raised intraocular pressure and cataract may occur. As it was so effective in these eyes with resistant CMO, a larger study is warranted to evaluate this form of therapy. [ABSTRACT FROM AUTHOR]

Published
2001

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