8 results on '"Lara, Leijser"'
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2. Hemodynamic Quality Improvement Bundle to Reduce the Use of Inotropes in Extreme Preterm Neonates
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Sujith Kumar Reddy Gurram Venkata, Ankur Srivastava, Prashanth Murthy, James N. Scott, Hussein Zein, Lara Leijser, Anirban Ghosh, Sarfaraz Momin, Sumesh Thomas, and Khorshid Mohammad
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Brain Injuries ,Pediatrics, Perinatology and Child Health ,Hemodynamics ,Infant, Newborn ,Humans ,Pharmacology (medical) ,Hypotension ,Quality Improvement ,Infant, Premature - Abstract
We evaluated the effect of the quality improvement (QI) bundle on the rate of inotrope use and associated morbidities.We included inborn preterm neonates born at 29 weeks admitted to level III NICU. We implemented a QI bundle focusing on the first 72 h from birth which included delayed cord clamping, avoidance of routine echocardiography, the addition of clinical criteria to the definition of hypotension, factoring iatrogenic causes of hypotension, and standardization of respiratory management. The rate of inotropes use was compared before and after implementing the care bundle. Incidence of cystic periventricular leukomalacia (cPVL) was used as a balancing measure.QI bundle implementation was associated with significant reduction in overall use of inotropes (24 vs 7%, p 0.001), dopamine (18 vs 5%, p 0.001), and dobutamine (17 vs 4%, p 0.001). Rate of acute brain injury decreased significantly: acute brain injury of any grade (34 vs 20%, p 0.001) and severe brain injury (15 vs 6%, p 0.001). There was no difference in the incidence of cPVL (0.8 vs 1.4%, p = 0.66). Associations remained significant after adjusting for confounding factors.A quality improvement bundled approach resulted in a reduction in inotropes use and associated brain morbidities in premature babies.
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- 2022
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3. Proceedings of the 13th International Newborn Brain Conference: Other forms of brain monitoring, such as NIRS, fMRI, biochemical
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Ekaterina Balashova, Olivia Beaulieu, Imen Benhmida, Ala Birca, Geraldine Boylan, Katherine Carkeek, Rasheda Chowdhury, Maria Roberta Cilio, Anna Consoli, Gabriel Cote Corriveau, Deborah Cuddyer, Dmitriy Degtyarev, Mathieu Dehaes, Eugene Dempsey, Anneleen Dereymaeker, Beatrice Desnous, Mohamed El-Dib, Elhaytham Elsayed, Henry A. Feldman, Daragh Finn, Maria Angela Franceschini, Shoshana Freeman, Marie-Michele Gagnon, Melanie Gagnon, Aisling Garvey, Anirban Ghosh, Yulia Golubtsova, P. Ellen Grant, Susanne C. Hay, Tim Hermans, Emily Herzberg, Chuan-Heng Hsiao, Maria Iennaco, Terrie Inder, Oleg Ionov, Kutlu Kaya, Faith Keister, Miriah Kemigisha, Anna Kirtbaya, Sarah Lee, Lara Leijser, Steve Liao, Pei-Yi Lin, Rachel Lippman, Vicki Livingstone, Thuy Mai Luu, Joshua Magombe, Zamzam Mahdi, Bohdana Marandyuk, Alyssa Martin, Sean Mathieson, Edith Mbabazi, Khorshid Mohammad, Michael Moore, Ronald Mulondo, Chelsea Munster, Deirdre Murray, Esther Nalule, Davis Natukwatsa, Gunnar Naulaers, Mona Noroozi, Brian Nsubuga, John O’Toole, Andreea Pavel, Mallory Peterson, Elana Pinchefsky, Katharine Playter, Jennifer Queally, Ajay Rajaram, Andrey Ryndin, Steven Schiff, Marvin Seruwu, Diiana Sharafutdinova, Yvonne Sheldon, Marie-Noelle Simard, Jessica Sims, Tina Steele, Amelie Stritzke, John Sunwoo, Jason Sutin, Julia Tatz, Taylor Vadset, Zachary Vesoulis, Rutvi Vyas, Moses Wabukoma, Brian Walsh, Joshua Wandukwa, Benjamin Warf, Halana Whitehead, Michael Woglom, Fan-Yu Yen, Lucca Zampolli, Alexander I. Zavriyev, Hussein Zein, Bernhard Zimmermann, and Victor Zubkov
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Pediatrics, Perinatology and Child Health - Published
- 2022
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4. Proceedings of the 13th International Newborn Brain Conference: Neonatal Neurocritical Care, Seizures, and Continuous EEG monitoring
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Nicholas Abend, Eleri Adams, Asim Al Balushi, Wissam Alburaki, Juan Appendino, Vargas Stephanie Barbosa, Ala Birca, Sonia Bonifacio, Aoife Branagan, Taeun Chang, Rasheda Chowdhury, Helen Christou, Catherine Chu, M. Roberta Cilio, Silvia Comani, María Corsi-Cabrera, Pierpaolo Croce, Lourdes Cubero-Rego, Fady Dawoud, Linda de Vries, Mathieu Dehaes, Declan Devane, Aubrey Duncan, Nathalie El Ters, Mohamed El-Dib, Hoda Elshibiny, Michael Esser, Karen Fairchild, Elaine Finucane, Maria Angela Franceschini, Anne Gallagher, Anirban Ghosh, Hannah Glass, Sujith Kumar Reddy Gurram Venkata, Thalía Harmony Baillet, Emily Herzberg, Emily Hildrey, Tim Hurley, Terrie Inder, Elke Jacobs, Kimberley Jefferies, Agnes Jermendy, Mohammad Khazaei, Keira Kilmartin, Graham King, Leena Lauronen, Sarah Lee, Lara Leijser, Janice Lind, Nathalie Sales Llaguno, Michelle Machie, Maurício Magalhães, Zamzam Mahdi, Julie Maluomi, Bohdana Marandyuk, Shavonne Massey, Charles McCulloch, Marjo Metsäranta, Kirsi Mikkonen, Khorshid Mohammad, Eleanor Molloy, Sarfaraz Momin, Chelsea Munster, Prashanth Murthy, Alexandre Netto, Päivi Nevalainen, Jennifer Nguyen, Maria Nieves, Jenna Nyman, Norma Oliver, Cacha Peeters, Rafaela Fabri Rodrigues Pietrobom, Judith Pijpers, Elana Pinchefksy, Yee Billie Ping, Fiona Quirke, Khadijeh Raeisi, Josefina Ricardo-Garcell, Jill Robinson, Daniela Pereira Rodrigues, Justin Rosati, James Scott, Maxine Scringer-Wilkes, Renée Shellhaas, Liesbeth Smit, Janet Soul, Ankur Srivastava, Sylke Steggerda, John Sunwoo, Eniko Szakmar, Gabriella Tamburro, Sumesh Thomas, Sanna Toiviainen-Salo, Adrian Ioan Toma, Sampsa Vanhatalo, Gabriel Fernando Todeschi Variane, Alla Vein, Zachary Vesoulis, Ana Vilan, Joseph Volpe, Lauren Weeke, Pia Wintermark, Courtney Wusthoff, Filippo Zappasodi, Hussein Zein, and John Zempel
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Pediatrics, Perinatology and Child Health - Published
- 2022
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5. Proceedings of the 13th International Newborn Brain Conference: Neuro-imaging studies
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Ramy Abramsky, Rebeka Acosta, Laura Acosta Izquierdo, Bushra Albeshri, Mountasser Almouqdad, Yasmeen Asfour, Suzan Asfour, Topun Austin, Ashley Bach, Jim Barkovich, Richard Beare, Nadya Ben Fadel, Angelika Berger, Borja Blanco, Martijn Boomsma, Samudragupta Bora, Vivian Boswinkel, Theresa Chin, Liam Collins-Jones, Robert Cooper, Gautam Dagur, Jorge Davila, Linda de Vries, Laxmikant Shesrao, null Deshmukh, Gregor Dovjak, Andrea Edwards, Mohamed El-Dib, Hoda Elshibiny, Dafna Eshel, Ron Eshel, Donna Ferriero, Dawn Gano, Olivia Girvan, Hannah Glass, Katharina Goeral, Agneta Golan, Michelle Gurvitz, Terrie Inder, Dima Jamjoom, Nadja Kadom, Gregor Kasprian, Thanaa Khalil, Katrin Klebermass-Schrehof, Jake Kleinmahon, Martine Krüse-Ruijter, Hannah Lambing, Sarah Lee, Alexander Leemans, Lara Leijser, Brigitte Lemyre, Yi Li, Camille Maltais-Bilodeau, Kyla Marks, Charles McCulloch, Sarah Milla, Elka Miller, Aradhana Mishra, Nicholas Mitsakakis, Khorshid Mohammad, Susanne Mulder-de Tollenaer, Chelsea Munster, Jacqueline Nijboer, Jacqueline Nijboer-Oosterveld, Ingrid Nijholt, Rosa Novoa, Cynthia Ortinau, Emma Porter, Daniela Prayer, Deepti Reddy, Stephanie Redpath, Elizabeth Rogers, Victor Schmidbauer, James Scott, Elizabeth Sewell, Eilon Shany, Ilan Shelef, Elizabeth Singh, Cornelis Slump, Tina Steele, Eniko Szakmar, Chantal Tax, Kirsten Thiim, Julie Uchitel, Jochen van Osch, Gerda van Wezel-Meijler, Anouk Verschuur, Mei-Nga Wu-Smit, Edward Yang, and Hussein Zein
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Pediatrics, Perinatology and Child Health - Published
- 2022
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6. Proceedings of the 13th International Newborn Brain Conference: Neuroprotection strategies in the neonate
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Ayman Abou Mehrem, Essa Al Awad, Kim Anninck, Stephanie Au-Young, Nesil Aydinol, Peter Bartmann, Manon Benders, Amina Benlamri, Leah Bolderheij, Yalcin Celik, Natalie Chan, Cecil Chau, Vann Chau, Xiaodi Chen, Claudia Chetcuti Ganado, Annaleen Coetser, Filip Cools, Giselle Da Rocha, Hans-Peter Deigner, Anneleen Dereymaeker, Laxmikant Deshmukh, Rose Domonoske, Salma Dossani, Jeanne M Dsouza, Mayy El Gamal, Peace Eshemokhai, Michael Esser, Elsa Fiedrich, Axel Franz, Anirban Ghosh, Floris Groenendaal, Ruth E. Grunau, Sujith Kumar Reddy Gurram Venkata, Serif Hamitoglu, Lena Hellström-Westas, Leigh Irvine, Katrien Jansen, Artem Javadyan, Graham Jenkin, Noela Kamanga, Navneet Kaur, Elif Keles, Matthias Keller, Edmond Kelly, Samantha Jane Kesting, Dikeledi Kgwadi, Boram Kim, Matthias Kohl, Derek Kowal, Jennifer Damoi Kricitober, Lara Leijser, Mark LePine, Yow-Pin Lim, Abhay Lodha, Atul Londhe, Linh Ly, Eva Maes, Atul Malhotra, Neil Marlow, Joseph L Mathew, Courtney McDonald, Mia McLean, Cathy Metcalfe, Ron Meyer, Steven P. Miller, Suzanne Miller, Tshiamo Mogajane, Khorshid Mohammad, Sarfaraz Momin, John Montpetit, Nelson Mukiza, Prashanth Murthy, James N Scott, Victoria Nakibuuka, Firdose Nakwa, Gunnar Naulaers, Jennessa Noort, Nandi Ntuli, Claude Ondongo-Ezhet, Renee Paul, Michael Pepper, Achim Plum, Bryan Rombough, Ola Saugstad, Jillian Scotland, James Scott, Karabo Seake, Robert Sebunya, Thiviya Selvanathan, Letlhogonolo Sepeng, Huseyin Simsek, Carola Steins-Rang, Barbara Stonestreet, Selphee Tang, Erdal Taskin, Liesbeth Thewissen, Sumesh Thomas, Reenu Thomas, Alison van Kwawegen, Jeanne van Rensburg, Sithembiso Velaphi, Yuqi Wu, Akan Yaman, Hacer Yapicioglu-Yildizdas, Tamara Yawno, Pearl Zaki, Hussein Zein, and Lindsay Zhou
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Pediatrics, Perinatology and Child Health - Published
- 2022
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7. 19 Quality Improvement bundled approach reduces the use of inotropes in extremely premature babies
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Sujith Kumar Reddy Gurram Venkata, Ankur Srivastava, Prashanth Murthy, James Scott, Hussein Zein, Lara Leijser, Anirban Ghosh, Sarfaraz Momin, Sumesh Thomas, and Khorshid Mohammad
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Pediatrics, Perinatology and Child Health - Abstract
Background Consensus on definition and management of hypotension in preterm neonates is lacking. Owing to this, there are wide variations in the reported incidence of hypotension in premature infants, especially during first week of life. Inotropes can often cause vasoconstriction, which may alter brain perfusion especially in the absence of established cerebral autoregulation. Use of these drugs is associated with multiple short- and long-term morbidities. Objectives To evaluate the effect of quality improvement (QI) bundle on rate of inotrope use and associated morbidities. Design/Methods Inborn preterm neonates born at Results We included 671 neonates (301 before and 364 after the implementation of the bundle) among which 6 neonates were excluded based on the criteria. QI bundle implementation was associated with significant reduction in overall use of inotropes (24% vs 7%, p Conclusion Our QI bundled approach resulted in reduction in inotrope use and associated brain morbidities in premature babies. Follow-up studies evaluating the impact of this initiative on long-term outcomes in survivors are required to complement findings of improved short-term outcomes seen in this study.
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- 2022
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8. Neuroprotection Care Bundle Implementation is Associated with Improved Long-Term Neurodevelopmental Outcomes in Extremely Premature Infants
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amina ahlem benlamri, prashanth Murthy, Hussein Zein, Sumesh Thomas, James N. Scott, Ayman Abou Mehrem, Michael J. Esser, abhay Lodha, Jennessa Noort, selphee Tang, Cathy Metcalfe, Derek Kowal, leigh irvine, Jillian Scotland, lara leijser, and Khoshid Mohammad
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History ,Polymers and Plastics ,Business and International Management ,Industrial and Manufacturing Engineering - Published
- 2022
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