Search

We used data from 3041 participants in four cohorts of community-dwelling individuals aged ≥65 years in Spain collected through a pre-pandemic face-to-face interview and a telephone interview conducted between weeks 7 to 15 after the beginning of the COVID-19 lockdown. On average, the confinement was not associated with a deterioration in lifestyle risk factors (smoking, alcohol intake, diet, or weight), except for a decreased physical activity and increased sedentary time, which reversed with the end of confinement. However, chronic pain worsened, and moderate declines in mental health, that did not seem to reverse after restrictions were lifted, were observed. Males, older adults with greater social isolation or greater feelings of loneliness, those with poorer housing conditions, as well as those with a higher prevalence of chronic morbidities were at increased risk of developing unhealthier lifestyles or mental health declines with confinement. On the other hand, previously having a greater adherence to the Mediterranean diet and doing more physical activity protected older adults from developing unhealthier lifestyles with confinement. If another lockdown were imposed during this or future pandemics, public health programs should specially address the needs of older individuals with male sex, greater social isolation, sub-optimal housing conditions, and chronic morbidities because of their greater vulnerability to the enacted movement restrictions The Seniors-ENRICA-2 study was supported by Instituto de Salud Carlos III (Spain), State Secretary of R+D+I and FEDER/FSE research grants PI16/609, PI18/287, and 19/319; CIBERESP (16/01); and Cátedra de Epidemiología y Control del Riesgo Cardiovascular at UAM (#820024). ELS was supported by a Juan de la Cierva Contract from the Ministy of Universities. DMG and MSP were supported by supported by a “Ramon y Cajal”contract. Edad con Salud was funded by the Seventh Framework Programme (grant number 223071-COURAGE Study); the Insti tuto de Salud Carlos III (grants number PS09/00295(JMH), PS09/01845 (JLA), PI12/01490 (JMH), PI13/00059 (JLA), PI16/00212 (JMH), PI16/00218 (MM), PI16/01073 (JLA)); the European Regional Development Fund (ERDF) “A Way to Build Europe” (grant numbers PI12/01490, PI13/00059, PI16/00212 and PI16/01073);and CIBERSAM. EL was supported by the Sara Borrell postdoctoral programme (CD18/00099) from the Instituto de Salud Carlos III and co-funded by the European Union (FEDER/FSE, “Investing in your future”). BO was supported by the Miguel Servet programme (reference CP20/00040), funded by Instituto de Salud Carlos III and co-funded by European Union (ERDF/ESF, "Investing in your future"). The Toledo Study for Healthy Ageing was funded by the Spanish Ministry of Economy, Industry and Competitiveness, cofinanced by FEDER (RD120001/0043), CIBERFES (CB16/10/00464) and DIABFRAIL-LATAM (contract number 825546, Horizon 2020). The Elderly EXERNET multicenter study was supported by the Ministerio de Economía, Industria y Competitividad (DEP2016-78309-R (GVR)), the Ministerio de Educación y Ciencia (Red EXERNET DEP2005-00046 JAC)), the High Council of Sports (Consejo Superior de Deportes) of the Ministe rio de Cultura y Deportes (09/UPB/19 (JAC) and 45/UPB/20 (JAC)), CIBERFES, the 4IE+ project (0499_4IE_PLUS_4_E (NG)) funded by the Interreg V-A España-Portugal (POCTEP) 2014-2020 pro gram, and FEDER funds from the European Union (CB16/10/00477 (IA)). The funding agencies had no role in study design, data collection and analysis, interpretation of results, manuscript preparation or the decision to submit this manuscript for publication

Aims. To assess whether there is a change in the prevalence of depression and suicidal ideation after the strict lockdown measures due to the first wave of the COVID-19 pandemic in Spain; and to assess which are the factors associated with the incidence of a depressive episode or suicidal ideation during the lockdown. Methods. Data from a longitudinal adult population-based cohort from the provinces of Madrid and Barcelona were analysed (n = 1103). Structured face-to-face home-based interviews (pre-pandemic) and telephone interviews were performed. Both depression and suicidal ideation were assessed through an adaptation of the Composite International Diagnostic Interview (CIDI 3.0). A variety of validated instruments and sociodemographic variables including age, sex, educational level, occupational status, home quietness, screen time, resilience, loneliness, social support, physical activity, disability, economic situation and COVID-19-related information were also considered. Population prevalence estimates and multivariable logistic regressions were computed. Results. Overall, prevalence rates of depression and suicidal ideation did not change significantly from before to after the COVID-19 outbreak. However, the rates of depression among individuals aged 50+ years showed a significant decrease compared to before the pandemic (from 8.48 to 6.41%; p = 0.01). Younger individuals (odds ratio (OR) = 0.97 per year older; 95% confidence interval (CI) = 0.95–0.99) and those feeling loneliness (OR = 1.96; 95% CI = 1.42–2.70) during the lockdown were at an increased risk of developing depression during the confinement. Resilience showed a protective effect against the risk of depression (OR = 0.46; 95% CI = 0.32–0.66) and suicidal ideation (OR = 0.33; 95% CI = 0.16–0.68), whereas individuals perceiving social support were at a lower risk of developing suicidal thoughts (OR = 0.35; 95% CI = 0.18–0.69). Conclusions. Continuous reinforcement of mental health preventive and intervening measures during and in the aftermath of the crisis is of global importance, particularly among vulnerable groups who are experiencing the most distress. Future research should strive to evaluate the long-term effects of the COVID-19 crisis on mental health. E. L.’s work is supported by the Sara Borrell postdoctoral programme (CD18/00099) from the Instituto de Salud Carlos III (Spain) and co-funded by European Union (ERDF/ESF, ‘Investing in your future’). The authors sincerely appreciate the generous contribution of all the participants, which made this work possible. This work was funded by the Instituto de Salud Carlos III (J. L. A. M., grant numbers PI16/00218 and PI19/00150), (J. M. H., grantnumber PI16/01073 and PI19/00088), (M. M., grant number PI19/00235), (B. O., gran number PI19/00103), the Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), and by the European Union’s Horizon 2020 under Grant Agreement No 101016127

Aims: Cognitive deficits are an important factor in the pathogenesis of psychosis. Subjective cognitive complaints (SCCs) are often considered to be a precursor of objective cognitive deficits, but there are no studies specifically on SCC and psychotic experiences. Thus, we assessed the association between SCC and psychotic experiences using data from 48 low- and middle-income countries.\ud Methods: Community-based cross-sectional data of the World Health Survey were analyzed. Two questions on subjective memory and learning complaints in the past 30 days were used to create a SCC scale ranging from 0 to 10 with higher scores representing more severe SCC. The Composite International Diagnostic Interview was used to identify past 12-month psychotic experiences. Multivariable logistic regression and mediation analyses were performed.\ud Results: The final sample consisted of 224,842 adults aged ≥18 years [mean (SD) age 38.3 (16.0) years; 49.3% males]. After adjustment for sociodemographic factors, a one-unit increase in the SCC scale was associated with a 1.17 (95%CI=1.16-1.18) times higher odds for psychotic experiences in the overall sample, with this association being more pronounced in younger individuals: age 18-44 years OR=1.19 (95%CI=1.17-1.20); 45-64 years OR=1.15 (95%CI=1.12-1.17); ≥65 years OR=1.14 (95%CI=1.09-1.19). Collectively, other mental health conditions (perceived stress, depression, anxiety, sleep problems) explained 43.4% of this association, and chronic physical conditions partially explained the association but to a lesser extent (11.8%). \ud Conclusions: SCC were associated with psychotic experiences. Future longitudinal studies are needed to understand temporal associations and causal inferences, while the utility of SCC as a risk marker for psychosis especially for young adults should be scrutinized.