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1. HighNESS Conceptual Design Report: Volume I

Author

Santoro, V., Kheir, O. Abou El, Acharya, D., Akhyani, M., Andersen, K. H., Barrow, J., Bentley, P., Bernasconi, M., Bertelsen, M., Bessler, Y., Bianchi, A., Brooijmans, G., Broussard, L., Brys, T., Busi, M., Campi, D., Chambon, A., Chen, J., Czamler, V., Deen, P., DiJulio, D. D., Dian, E., Draskovits, L., Dunne, K., Barbari, M. El, Ferreira, M. J., Fierlinger, P., Fröst, V. T., Folsom, B. T., Friman-Gayer, U., Gaye, A., Gorini, G., Gustafsson, A., Gutberlet, T., Happe, C., Han, X., Hartl, M., Holl, M., Jackson, A., Kemp, E., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Lejon, W., Linander, R., Lindroos, M., Marko, M., Damián, J. I. Márquez, McClanahan, T. C., Meirose, B., Mezei, F., Michel, K., Milstead, D., Muhrer, G., Nepomuceno, A., Neshvizhevsky, V., Nilsson, T., Odén, U., Plivelic, T., Ramic, K., Rataj, B., Remec, I., Rizzi, N., Rogers, J., Rosenthal, E., Rosta, L., Rücker, U., Samothrakitis, S., Schreyer, A., Selknaes, J. R., Shuai, H., Silverstein, S., Snow, W. M., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Yngwe, L., Young, A. R., Wolke, M., Zakalek, P., Zavorka, L., Zanini, L., and Zimmer, O.

Subjects
Physics - Instrumentation and Detectors
Abstract

The European Spallation Source, currently under construction in Lund, Sweden, is a multidisciplinary international laboratory. Once completed to full specifications, it will operate the world's most powerful pulsed neutron source. Supported by a 3 million Euro Research and Innovation Action within the EU Horizon 2020 program, a design study (HighNESS) has been completed to develop a second neutron source located below the spallation target. Compared to the first source, designed for high cold and thermal brightness, the new source has been optimized to deliver higher intensity, and a shift to longer wavelengths in the spectral regions of cold (CN, 2--20\,\AA), very cold (VCN, 10--120\,\AA), and ultracold (UCN, ${>}\,{500}$\,\AA) neutrons. The second source comprises a large liquid deuterium moderator designed to produce CN and support secondary VCN and UCN sources. Various options have been explored in the proposed designs, aiming for world-leading performance in neutronics. These designs will enable the development of several new instrument concepts and facilitate the implementation of a high-sensitivity neutron-antineutron oscillation experiment (NNBAR). This document serves as the Conceptual Design Report for the HighNESS project, representing its final deliverable., Comment: 269 pages, 255 figures. Volume I of the final deliverable of the HighNESS Project (HORIZON 2020 grant agreement ID: 951782)

Published
2023
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2. Traduction et republication de : « Traitement de la maladie thromboembolique veineuse associée au cancer chez les patients en soins palliatifs »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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3. Traduction et republication de : « Prise en charge de la maladie thromboembolique veineuse associée au cancer chez les populations vulnérables »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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4. Traduction et republication de : « Thrombose veineuse profonde du membre supérieur associée à un cathéter veineux central chez les patients cancéreux : diagnostic et prise en charge thérapeutique »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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5. Traduction et republication de : « Maladie thromboembolique veineuse récidivante chez les patients cancéreux anticoagulés : diagnostic et traitement »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Bugat, M.-È.R., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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7. Intensive disc-reverberation mapping of Fairall 9: 1st year of Swift & LCO monitoring

Author

Santisteban, J. V. Hernández, Edelson, R., Horne, K., Gelbord, J. M., Barth, A. J., Cackett, E. M., Goad, M. R., Netzer, H., Starkey, D., Uttley, P., Brandt, W. N., Korista, K., Lohfink, A. M., Onken, C. A., Page, K. L., Siegel, M., Vestergaard, M., Bisogni, S., Breeveld, A. A., Cenko, S. B., Bontà, E. Dalla, Evans, P. A., Ferland, G., Gonzalez-Buitrago, D. H., Grupe, D., Joner, M. D., Kriss, G., LaPorte, S. J., Mathur, S., Marshall, F., Mehdipour, M., Mudd, D., Peterson, B. M., Schmidt, T., Vaughan, S., and Valenti, S.

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - High Energy Astrophysical Phenomena
Abstract

We present results of time-series analysis of the first year of the Fairall 9 intensive disc-reverberation campaign. We used Swift and the Las Cumbres Observatory global telescope network to continuously monitor Fairall 9 from X-rays to near-infrared at a daily to sub-daily cadence. The cross-correlation function between bands provides evidence for a lag spectrum consistent with the $\tau\propto\lambda^{4/3}$ scaling expected for an optically thick, geometrically thin blackbody accretion disc. Decomposing the flux into constant and variable components, the variable component's spectral energy distribution is slightly steeper than the standard accretion disc prediction. We find evidence at the Balmer edge in both the lag and flux spectra for an additional bound-free continuum contribution that may arise from reprocessing in the broad-line region. The inferred driving light curve suggests two distinct components, a rapidly variable ($<4$ days) component arising from X-ray reprocessing, and a more slowly varying ($>100$ days) component with an opposite lag to the reverberation signal., Comment: 19 pages, 12 figures, accepted in MNRAS

Published
2020
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10. HighNESS conceptual design report: Volume II. the NNBAR experiment

Author

Santoro, V, Abou El Kheir, O, Acharya, D, Akhyani, M, Andersen, K, Barrow, J, Bentley, P, Bernasconi, M, Bertelsen, M, Beßler, Y, Bianchi, A, Brooijmans, G, Broussard, L, Brys, T, Busi, M, Campi, D, Chambon, A, Chen, J, Czamler, V, Deen, P, Dijulio, D, Dian, E, Draskovits, L, Dunne, K, El Barbari, M, Ferreira, M, Fierlinger, P, Fröst, V, Folsom, B, Friman-Gayer, U, Gaye, A, Gorini, G, Gustafsson, A, Gutberlet, T, Happe, C, Han, X, Hartl, M, Holl, M, Jackson, A, Kemp, E, Kamyshkov, Y, Kittelmann, T, Klinkby, E, Kolevatov, R, Laporte, S, Lauritzen, B, Lejon, W, Linander, R, Lindroos, M, Marko, M, Márquez Damián, J, Mcclanahan, T, Meirose, B, Mezei, F, Michel, K, Milstead, D, Muhrer, G, Nepomuceno, A, Neshvizhevsky, V, Nilsson, T, Odén, U, Plivelic, T, Ramic, K, Rataj, B, Remec, I, Rizzi, N, Rogers, J, Rosenthal, E, Rosta, L, Rücker, U, Samothrakitis, S, Schreyer, A, Selknaes, J, Shuai, H, Silverstein, S, Snow, W, Strobl, M, Strothmann, M, Takibayev, A, Wagner, R, Willendrup, P, Xu, S, Yiu, S, Yngwe, L, Young, A, Wolke, M, Zakalek, P, Zavorka, L, Zanini, L, Zimmer, O, Santoro V., Abou El Kheir O., Acharya D., Akhyani M., Andersen K. H., Barrow J., Bentley P., Bernasconi M., Bertelsen M., Beßler Y., Bianchi A., Brooijmans G., Broussard L., Brys T., Busi M., Campi D., Chambon A., Chen J., Czamler V., Deen P., Dijulio D. D., Dian E., Draskovits L., Dunne K., El Barbari M., Ferreira M. J., Fierlinger P., Fröst V. T., Folsom B. T., Friman-Gayer U., Gaye A., Gorini G., Gustafsson A., Gutberlet T., Happe C., Han X., Hartl M., Holl M., Jackson A., Kemp E., Kamyshkov Y., Kittelmann T., Klinkby E. B., Kolevatov R., Laporte S. I., Lauritzen B., Lejon W., Linander R., Lindroos M., Marko M., Márquez Damián J. I., McClanahan T. C., Meirose B., Mezei F., Michel K., Milstead D., Muhrer G., Nepomuceno A., Neshvizhevsky V., Nilsson T., Odén U., Plivelic T., Ramic K., Rataj B., Remec I., Rizzi N., Rogers J., Rosenthal E., Rosta L., Rücker U., Samothrakitis S., Schreyer A., Selknaes J. R., Shuai H., Silverstein S., Snow W. M., Strobl M., Strothmann M., Takibayev A., Wagner R., Willendrup P., Xu S., Yiu S. C., Yngwe L., Young A. R., Wolke M., Zakalek P., Zavorka L., Zanini L., Zimmer O., Santoro, V, Abou El Kheir, O, Acharya, D, Akhyani, M, Andersen, K, Barrow, J, Bentley, P, Bernasconi, M, Bertelsen, M, Beßler, Y, Bianchi, A, Brooijmans, G, Broussard, L, Brys, T, Busi, M, Campi, D, Chambon, A, Chen, J, Czamler, V, Deen, P, Dijulio, D, Dian, E, Draskovits, L, Dunne, K, El Barbari, M, Ferreira, M, Fierlinger, P, Fröst, V, Folsom, B, Friman-Gayer, U, Gaye, A, Gorini, G, Gustafsson, A, Gutberlet, T, Happe, C, Han, X, Hartl, M, Holl, M, Jackson, A, Kemp, E, Kamyshkov, Y, Kittelmann, T, Klinkby, E, Kolevatov, R, Laporte, S, Lauritzen, B, Lejon, W, Linander, R, Lindroos, M, Marko, M, Márquez Damián, J, Mcclanahan, T, Meirose, B, Mezei, F, Michel, K, Milstead, D, Muhrer, G, Nepomuceno, A, Neshvizhevsky, V, Nilsson, T, Odén, U, Plivelic, T, Ramic, K, Rataj, B, Remec, I, Rizzi, N, Rogers, J, Rosenthal, E, Rosta, L, Rücker, U, Samothrakitis, S, Schreyer, A, Selknaes, J, Shuai, H, Silverstein, S, Snow, W, Strobl, M, Strothmann, M, Takibayev, A, Wagner, R, Willendrup, P, Xu, S, Yiu, S, Yngwe, L, Young, A, Wolke, M, Zakalek, P, Zavorka, L, Zanini, L, Zimmer, O, Santoro V., Abou El Kheir O., Acharya D., Akhyani M., Andersen K. H., Barrow J., Bentley P., Bernasconi M., Bertelsen M., Beßler Y., Bianchi A., Brooijmans G., Broussard L., Brys T., Busi M., Campi D., Chambon A., Chen J., Czamler V., Deen P., Dijulio D. D., Dian E., Draskovits L., Dunne K., El Barbari M., Ferreira M. J., Fierlinger P., Fröst V. T., Folsom B. T., Friman-Gayer U., Gaye A., Gorini G., Gustafsson A., Gutberlet T., Happe C., Han X., Hartl M., Holl M., Jackson A., Kemp E., Kamyshkov Y., Kittelmann T., Klinkby E. B., Kolevatov R., Laporte S. I., Lauritzen B., Lejon W., Linander R., Lindroos M., Marko M., Márquez Damián J. I., McClanahan T. C., Meirose B., Mezei F., Michel K., Milstead D., Muhrer G., Nepomuceno A., Neshvizhevsky V., Nilsson T., Odén U., Plivelic T., Ramic K., Rataj B., Remec I., Rizzi N., Rogers J., Rosenthal E., Rosta L., Rücker U., Samothrakitis S., Schreyer A., Selknaes J. R., Shuai H., Silverstein S., Snow W. M., Strobl M., Strothmann M., Takibayev A., Wagner R., Willendrup P., Xu S., Yiu S. C., Yngwe L., Young A. R., Wolke M., Zakalek P., Zavorka L., Zanini L., and Zimmer O.

Abstract

A key aim of the HighNESS project for the European Spallation Source is to enable cutting-edge particle physics experiments. This volume presents a conceptual design report for the NNBAR experiment. NNBAR would exploit a new cold lower moderator to make the first search in over thirty years for free neutrons converting to anti-neutrons. The observation of such a baryon-number-violating signature would be of fundamental significance and tackle open questions in modern physics, including the origin of the matter-antimatter asymmetry. This report shows the design of the beamline, supermirror focusing system, magnetic and radiation shielding, and anti-neutron detector necessary for the experiment. A range of simulation programs are employed to quantify the performance of the experiment and show how background can be suppressed. For a search with full background suppression, a sensitivity improvement of three orders of magnitude is expected, as compared with the previous search. Civil engineering studies for the NNBAR beamline are also shown, as is a costing model for the experiment.

Published
2024

11. Traduction et republication de : « Prise en charge de la maladie thromboembolique veineuse associée au cancer chez les populations vulnérables »

Author

Laporte, S., primary, Benhamou, Y., additional, Bertoletti, L., additional, Frère, C., additional, Hanon, O., additional, Couturaud, F., additional, Moustafa, F., additional, Mismetti, P., additional, Sanchez, O., additional, Mahé, I., additional, Benmaziane, A., additional, Bichon, V., additional, Bozec, C., additional, Cohen, A., additional, Debourdeau, P., additional, Dielenseger, P., additional, Douriez, É., additional, Élias, A., additional, Espitia, O., additional, Gaboreau, Y., additional, Gendron, P., additional, Girard, P., additional, Idbaih, A., additional, Laporte, S., additional, Mayeur, D., additional, Pernod, G., additional, Roy, P.-M., additional, Rouge Bugat, M.-È., additional, Schmidt, J., additional, Scotté, F., additional, and Sevestre, M.-A., additional

Published
2024
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12. Traduction et republication de : « Maladie thromboembolique veineuse récidivante chez les patients cancéreux anticoagulés : diagnostic et traitement »

Author

Bertoletti, L., primary, Girard, P., additional, Élias, A., additional, Espitia, O., additional, Schmidt, J., additional, Couturaud, F., additional, Mahé, I., additional, Sanchez, O., additional, Benhamou, Y., additional, Benmaziane, A., additional, Bertoletti, L., additional, Bichon, V., additional, Bozec, C., additional, Cohen, A., additional, Debourdeau, P., additional, Dielenseger, P., additional, Douriez, É., additional, Frère, C., additional, Gaboreau, Y., additional, Gendron, P., additional, Hanon, O., additional, Idbaih, A., additional, Laporte, S., additional, Mayeur, D., additional, Mismetti, P., additional, Moustafa, F., additional, Pernod, G., additional, Roy, P.-M., additional, Bugat, M.-È.R., additional, Scotté, F., additional, and Sevestre, M.-A., additional

Published
2024
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15. Prevention of venous thromboembolism and haemostasis monitoring in patients with COVID-19: Updated proposals (April 2021): From the French working group on perioperative haemostasis (GIHP) and the French study group on thrombosis and haemostasis (GFHT), in collaboration with the French society of anaesthesia and intensive care (SFAR)

Author

Albaladejo, P., Blais, N., Bonhomme, F., Borel-Derlon, A., Cohen, A., Collet, J.-P., de Maistre, E., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Godon, A., Ickx, B., Laporte, S., Lasne, D., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Levy, J.H., Longrois, D., Madi-Jebara, S., Mansour, A., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Schlumberger, S., Sié, P., Steib, A., Susen, S., Tacquard, C.A., Testa, S., Vincentelli, A., Zufferey, P., Boissier, E, Dumont, B, James, C, Siguret, V., Godon, Alexandre, Tacquard, Charles Ambroise, Mansour, Alexandre, Garrigue, Delphine, Nguyen, Philippe, Lasne, Dominique, Testa, Sophie, Levy, Jerrold H., Albaladejo, Pierre, Gruel, Yves, Susen, Sophie, and Godier, Anne

Published
2021
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16. Link between postoperative ileus and anastomotic leakage: A structural equation modelling approach

Author

Abderrazak, M., Abolo, H., Abras, N., Aissou, M., Albertini, S., Alfonsi, P., Andre, A., Arimont, J.M., Arnalsteen, L., Atger, J., Attias, A., Aumont, O., Auvray, S., Bachmann, R., Barabino, G., Barsotti, P., Beauchesne, B., Beaupel, N., Beliard, A., Bellouard, A., Beloeil, H., Ben Salem, F., Benhamou, A., Billard, V., Binhas, M., Binot, D., Blache, J.L., Blet, A., Bongiovanni, J.P., Bonnal, A., Bonnet, M., Boret, H., Bossard, A.E., Bothereau, H., Bouarroudj, N., Bouayed, A., Bouchard, F., Boumadani, M., Bousquet, M., Bouygues, V., Bozio, G., Brek, A., Cadi, P., Caillon, P., Camerlo, A., Capito, C., Cardin, J.L., Castiglioni, M., Catinois, M.L., Cattan, P., Chambrier, C., Chambrier, G., Chapuis, O., Chauvin, M., Chokairi, S., Chopin Laly, X., Collange, V., Cotte, E., Cuellar, E., D'errico, E., Dahmani, S., Danan, M., De La Fontaine, C., De Wailly, P., Degauque, C., Delacoste, F., Denet, C., Denost, Q., Desaint, P., Descamps, E., Desfourneaux., V, Desmet, J., Desolneux, G., Dileon, S., Dolbeau, J.B., Douard, R., Dufour, F., Dupont-Bierre, E., Dupré, A., Entremont, A., Faucheron, J.L., Fernoux, P., Figuet, S., Finianos, A., Flamein, R., Fletcher, D., Fontes, J.P., Fourn, E., Gergeanu, S., Germain, A., Gignoux, B., Goater, P., Gres., P, Grigoroiu, M., Grillo, P., Guignard, B., Guinier, D., Guiot, J.L., Gutton, C., Hadjadj, H., Hail, K., Hausermann, M.H., Hennequin, S., Homsy-Hubert, B., Jambet, S., Janecki, T., Jannier-Guillou, V., Jaspart, J., Joly, F., Joris, J., Journe, F., Kattou, F., Kemoun, G., Khalaf, M., Klack, F., Kothonidis, K., Kurdi, O., Laforest, A., Lamblin, A., Lammens, S., Laporte, S., Launay-Savary, M.V., Le Maho, A.L., Lemée, J.M., Leonard, D., Leporrier, J., Lorin, J.L., Magne, E., Maisonnette, F., Malherbe, V., Manceau, G., Mariani, P., Massalou, D., Massard, J.L., Mauvais, F., Mbuyamba, J., Mbuyamba Katapile, J., Mehila, T., Meillat, H., Mergui, C., Michaud, P., Milou, F., Mirre, F., Mor Martinez, C., Mouchon, S., Mouilhade, F., Nguyen, Y.L., Ostermann Bucher, S., Page, M., Parent, S., Payen, A.L., Pedicone, R., Peluchon, P., Pichot-Delahaye, V., Piquard, A., Pirlet, I., Plard, L., Poiblanc, M., Poinas, G., Poincenot, J., Ponchel, C., Pontallier, A., Pop, R., Potiron, E., Proske, J.M., Prunet, B., Ras, E., Raspado, O., Raux, M., Regimbeau, J.M., Remue, C., Renacco, F., Riboud, R., Richard-Payen, A.L., Rio, D., Sage, M., Sage, P.Y., Saint Denis, M., Salaun, P., Samyn, B., Sbai Idrissi, M., Schmitt, G., Secq, E., Seddiki, A., Sens, N., Sirieix, D., Siriser, F., Tarcea, M., Tavernier, M., Tete, B., Theissen-Laval, O., Thevenot, A., Thievenaz, R., Vacher, B., Verhaeghe, R., Verrier, J.F., Vieuille, C., Voilin, C., Vuagnat, C., Zaepfel, S., Venara, Aurélien, Hamel, Jean-Francois, Beyer-Berjot, Laura, Vignaud, Timothée, and Slim, Karem

Published
2021
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18. Recommandations de bonne pratique pour la prise en charge de la maladie veineuse thromboembolique chez l’adulte – Version longue

Author

Sanchez, O., Benhamou, Y., Bertoletti, L., Constans, J., Couturaud, F., Delluc, A., Elias, A., Fischer, A.-M., Frappé, P., Gendron, N., Girard, P., Godier, A., Gut-Gobert, C., Laporte, S., Mahé, I., Mauge, L., Meneveau, N., Meyer, G., Mismetti, P., Parent, F., Pernod, G., Quéré, I., Revel, M.-P., Roy, P.-M., Salaün, P.-Y., Smadja, D.M., and Sevestre, M.-A.

Published
2021
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21. The HighNESS Project at the European Spallation Source : Current Status and Future Perspectives

Author

Santoro, V., Andersen, K. H., Bentley, P., Bernasconi, M., Bertelsen, M., Bessler, Y., Bianchi, A., Brys, T., Campi, D., Chambon, A., Czamler, V., Di Julio, D. D., Dian, E., Dunne, Katherine, Ferreira, M. J., Fierlinger, P., Friman-Gayer, U., Folsom, B. T., Gaye, A., Gorini, G., Happe, C., Holl, M., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Damian, J. I. Marquez, Meirose, Bernhard, Mezei, F., Milstead, David A., Muhrer, G., Neshvizhevsky, V., Rataj, B., Rizzi, N., Rosta, L., Samothrakitis, S., Schober, H., Selknaes, J. R., Silverstein, Samuel B., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Zanini, L., Zimmer, O., Santoro, V., Andersen, K. H., Bentley, P., Bernasconi, M., Bertelsen, M., Bessler, Y., Bianchi, A., Brys, T., Campi, D., Chambon, A., Czamler, V., Di Julio, D. D., Dian, E., Dunne, Katherine, Ferreira, M. J., Fierlinger, P., Friman-Gayer, U., Folsom, B. T., Gaye, A., Gorini, G., Happe, C., Holl, M., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Damian, J. I. Marquez, Meirose, Bernhard, Mezei, F., Milstead, David A., Muhrer, G., Neshvizhevsky, V., Rataj, B., Rizzi, N., Rosta, L., Samothrakitis, S., Schober, H., Selknaes, J. R., Silverstein, Samuel B., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Zanini, L., and Zimmer, O.

Abstract

The European Spallation Source (ESS), presently under construction in Lund, Sweden, is a multidisciplinary international laboratory that, once completed at full specifications, will operate the world's most powerful pulsed neutron source. Supported by a 3 M Euro Research and Innovation Action within the European Union Horizon 2020 program, a design study (HighNESS) is now underway to develop a second neutron source located below the spallation target. Compared to the first source, which is located above the spallation target and designed for high cold and thermal brightness, the new source is being optimized to deliver higher intensity and a shift to longer wavelengths in the spectral regions of cold neutrons (CNs) (2 to 20 & Aring;), very cold neutrons (VCNs) (10 to 120 & Aring;), and ultracold neutrons (UCNs) (> 500 & Aring;). The second source consists of a large liquid deuterium moderator to deliver CNs and serve secondary VCN and UCN sources, for which different options are under study. These new sources will boost several areas of condensed matter research and will provide unique opportunities in fundamental physics. The HighNESS project is now entering its last year, and we are working toward the Conceptual Design Report of the ESS upgrade. In this paper, results obtained in the first 2 years, ongoing developments, and future perspectives are described.

Published
2024
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22. HighNESS conceptual design report:Volume II. the NNBAR experiment.

Author

Santoro, V., Abou El Kheir, O., Acharya, D., Akhyani, M., Andersen, K. H., Barrow, J., Bentley, P., Bernasconi, M., Bertelsen, M., Beßler, Y., Bianchi, A., Brooijmans, G., Broussard, L., Brys, T., Busi, M., Campi, D., Chambon, A., Chen, J., Czamler, V., Deen, P., Dijulio, D. D., Dian, E., Draskovits, L., Dunne, K., El Barbari, M., Ferreira, M. J., Fierlinger, P., Fröst, V. T., Folsom, B. T., Friman-Gayer, U., Gaye, A., Gorini, G., Gustafsson, A., Gutberlet, T., Happe, C., Han, X., Hartl, M., Holl, M., Jackson, A., Kemp, E., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Lejon, W., Linander, R., Lindroos, M., Marko, M., Márquez Damián, J. I., McClanahan, T. C., Meirose, B., Mezei, F., Michel, K., Milstead, D., Muhrer, G., Nepomuceno, A., Neshvizhevsky, V., Nilsson, T., Odén, U., Plivelic, T., Ramic, K., Rataj, B., Remec, I., Rizzi, N., Rogers, J., Rosenthal, E., Rosta, L., Rücker, U., Samothrakitis, S., Schreyer, A., Selknaes, J. R., Shuai, H., Silverstein, S., Snow, W. M., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Yngwe, L., Young, A. R., Wolke, M., Zakalek, P., Zavorka, L., Zanini, L., Zimmer, O., Santoro, V., Abou El Kheir, O., Acharya, D., Akhyani, M., Andersen, K. H., Barrow, J., Bentley, P., Bernasconi, M., Bertelsen, M., Beßler, Y., Bianchi, A., Brooijmans, G., Broussard, L., Brys, T., Busi, M., Campi, D., Chambon, A., Chen, J., Czamler, V., Deen, P., Dijulio, D. D., Dian, E., Draskovits, L., Dunne, K., El Barbari, M., Ferreira, M. J., Fierlinger, P., Fröst, V. T., Folsom, B. T., Friman-Gayer, U., Gaye, A., Gorini, G., Gustafsson, A., Gutberlet, T., Happe, C., Han, X., Hartl, M., Holl, M., Jackson, A., Kemp, E., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Lejon, W., Linander, R., Lindroos, M., Marko, M., Márquez Damián, J. I., McClanahan, T. C., Meirose, B., Mezei, F., Michel, K., Milstead, D., Muhrer, G., Nepomuceno, A., Neshvizhevsky, V., Nilsson, T., Odén, U., Plivelic, T., Ramic, K., Rataj, B., Remec, I., Rizzi, N., Rogers, J., Rosenthal, E., Rosta, L., Rücker, U., Samothrakitis, S., Schreyer, A., Selknaes, J. R., Shuai, H., Silverstein, S., Snow, W. M., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Yngwe, L., Young, A. R., Wolke, M., Zakalek, P., Zavorka, L., Zanini, L., and Zimmer, O.

Abstract

A key aim of the HighNESS project for the European Spallation Source is to enable cutting-edge particle physics experiments. This volume presents a conceptual design report for the NNBAR experiment. NNBAR would exploit a new cold lower moderator to make the first search in over thirty years for free neutrons converting to anti-neutrons. The observation of such a baryon-number-violating signature would be of fundamental significance and tackle open questions in modern physics, including the origin of the matter-antimatter asymmetry. This report shows the design of the beamline, supermirror focusing system, magnetic and radiation shielding, and anti-neutron detector necessary for the experiment. A range of simulation programs are employed to quantify the performance of the experiment and show how background can be suppressed. For a search with full background suppression, a sensitivity improvement of three orders of magnitude is expected, as compared with the previous search. Civil engineering studies for the NNBAR beamline are also shown, as is a costing model for the experiment.

Published
2024

24. Diagnosis and management of heparin-induced thrombocytopenia

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Huet, D. Garrigue, Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Meyer, G., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., Testa, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Gruel, Yves, De Maistre, Emmanuel, Pouplard, Claire, Mullier, François, Susen, Sophie, Roullet, Stéphanie, Blais, Normand, Le Gal, Grégoire, Vincentelli, André, Lasne, Dominique, Lecompte, Thomas, Albaladejo, Pierre, and Godier, Anne

Published
2020
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25. The HighNESS Project at the European Spallation Source: Current Status and Future Perspectives

Author

Santoro, V, Andersen, K, Bentley, P, Bernasconi, M, Bertelsen, M, Bessler, Y, Bianchi, A, Brys, T, Campi, D, Chambon, A, Czamler, V, Di Julio, D, Dian, E, Dunne, K, Ferreira, M, Fierlinger, P, Friman-Gayer, U, Folsom, B, Gaye, A, Gorini, G, Happe, C, Holl, M, Kamyshkov, Y, Kittelmann, T, Klinkby, E, Kolevatov, R, Laporte, S, Lauritzen, B, Marquez Damian, J, Meirose, B, Mezei, F, Milstead, D, Muhrer, G, Neshvizhevsky, V, Rataj, B, Rizzi, N, Rosta, L, Samothrakitis, S, Schober, H, Selknaes, J, Silverstein, S, Strobl, M, Strothmann, M, Takibayev, A, Wagner, R, Willendrup, P, Xu, S, Yiu, S, Zanini, L, Zimmer, O, Santoro V., Andersen K. H., Bentley P., Bernasconi M., Bertelsen M., Bessler Y., Bianchi A., Brys T., Campi D., Chambon A., Czamler V., Di Julio D. D., Dian E., Dunne K., Ferreira M. J., Fierlinger P., Friman-Gayer U., Folsom B. T., Gaye A., Gorini G., Happe C., Holl M., Kamyshkov Y., Kittelmann T., Klinkby E. B., Kolevatov R., Laporte S. I., Lauritzen B., Marquez Damian J. I., Meirose B., Mezei F., Milstead D., Muhrer G., Neshvizhevsky V., Rataj B., Rizzi N., Rosta L., Samothrakitis S., Schober H., Selknaes J. R., Silverstein S., Strobl M., Strothmann M., Takibayev A., Wagner R., Willendrup P., Xu S., Yiu S. C., Zanini L., Zimmer O., Santoro, V, Andersen, K, Bentley, P, Bernasconi, M, Bertelsen, M, Bessler, Y, Bianchi, A, Brys, T, Campi, D, Chambon, A, Czamler, V, Di Julio, D, Dian, E, Dunne, K, Ferreira, M, Fierlinger, P, Friman-Gayer, U, Folsom, B, Gaye, A, Gorini, G, Happe, C, Holl, M, Kamyshkov, Y, Kittelmann, T, Klinkby, E, Kolevatov, R, Laporte, S, Lauritzen, B, Marquez Damian, J, Meirose, B, Mezei, F, Milstead, D, Muhrer, G, Neshvizhevsky, V, Rataj, B, Rizzi, N, Rosta, L, Samothrakitis, S, Schober, H, Selknaes, J, Silverstein, S, Strobl, M, Strothmann, M, Takibayev, A, Wagner, R, Willendrup, P, Xu, S, Yiu, S, Zanini, L, Zimmer, O, Santoro V., Andersen K. H., Bentley P., Bernasconi M., Bertelsen M., Bessler Y., Bianchi A., Brys T., Campi D., Chambon A., Czamler V., Di Julio D. D., Dian E., Dunne K., Ferreira M. J., Fierlinger P., Friman-Gayer U., Folsom B. T., Gaye A., Gorini G., Happe C., Holl M., Kamyshkov Y., Kittelmann T., Klinkby E. B., Kolevatov R., Laporte S. I., Lauritzen B., Marquez Damian J. I., Meirose B., Mezei F., Milstead D., Muhrer G., Neshvizhevsky V., Rataj B., Rizzi N., Rosta L., Samothrakitis S., Schober H., Selknaes J. R., Silverstein S., Strobl M., Strothmann M., Takibayev A., Wagner R., Willendrup P., Xu S., Yiu S. C., Zanini L., and Zimmer O.

Abstract

The European Spallation Source (ESS), presently under construction in Lund, Sweden, is a multidisciplinary international laboratory that, once completed at full specifications, will operate the world’s most powerful pulsed neutron source. Supported by a 3 M Euro Research and Innovation Action within the European Union Horizon 2020 program, a design study (HighNESS) is now underway to develop a second neutron source located below the spallation target. Compared to the first source, which is located above the spallation target and designed for high cold and thermal brightness, the new source is being optimized to deliver higher intensity and a shift to longer wavelengths in the spectral regions of cold neutrons (CNs) (2 to 20 Å), very cold neutrons (VCNs) (10 to 120 Å), and ultracold neutrons (UCNs) ((Formula presented.) 500 Å). The second source consists of a large liquid deuterium moderator to deliver CNs and serve secondary VCN and UCN sources, for which different options are under study. These new sources will boost several areas of condensed matter research and will provide unique opportunities in fundamental physics. The HighNESS project is now entering its last year, and we are working toward the Conceptual Design Report of the ESS upgrade. In this paper, results obtained in the first 2 years, ongoing developments, and future perspectives are described.

Published
2023

26. Republication de : Recommandations de bonne pratique pour la prise en charge de la maladie veineuse thromboembolique chez l’adulte. Version courte

Author

Sanchez, O., Benhamou, Y., Bertoletti, L., Constant, J., Couturaud, F., Delluc, A., Elias, A., Fischer, A.-M., Frappé, P., Gendron, N., Girard, P., Godier, A., Gut-Gobert, C., Laporte, S., Mahé, I., Mauge, L., Meneveau, N., Meyer, G., Mismetti, P., Parent, F., Pernod, G., Quéré, I., Revel, M.-P., Roy, P.-M., Salaün, P.-Y., Smadja, D.M., and Sevestre, M.-A.

Published
2019
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27. Gestion des agents antiplaquettaires en cas de procédure invasive non programmée ou d’hémorragie. Propositions du Groupe d’intérêt en hémostase périopératoire (GIHP) et du Groupe français d’études sur l’hémostase et la thrombose (GFHT) en collaboration avec la Société française d’anesthésie et de réanimation (SFAR)

Author

Belisle, S., Blais, N., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Faraoni, D., Garrigue Huet, D., Guay, J., Hardy, J.F., Huet, Y., Laporte, S., Levy, J.H., Llau, J., Le Gal, G., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Meyer, G., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Zufferey, P., Godier, Anne, Garrigue, Delphine, Lasne, Dominique, Fontana, Pierre, Bonhomme, Fanny, Collet, Jean-Philippe, de Maistre, Emmanuel, Ickx, Brigitte, Gruel, Yves, Mazighi, Mikael, Nguyen, Philippe, Vincentelli, André, Albaladejo, Pierre, and Lecompte, Thomas

Published
2019
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28. Recommandations de bonne pratique pour la prise en charge de la maladie veineuse thromboembolique chez l’adulte. Version courte

Author

Sanchez, O., Benhamou, Y., Bertoletti, L., Constant, J., Couturaud, F., Delluc, A., Elias, A., Fischer, A.-M., Frappé, P., Gendron, N., Girard, P., Godier, A., Gut-Gobert, C., Laporte, S., Mahé, I., Mauge, L., Meneveau, N., Meyer, G., Mismetti, P., Parent, F., Pernod, G., Quéré, I., Revel, M.-P., Roy, P.-M., Salaün, P.-Y., Smadja, D.M., and Sevestre, M.-A.

Published
2019
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29. Prevention of venous thromboembolic events in patients with lower leg immobilization after trauma: Systematic review and network meta-analysis with meta-epsidemiological approach

Author

Douillet, D., Chapelle, C., Ollier, E., Mismetti, P., Roy, P.-M., and Laporte, S.

Subjects
Leg -- Injuries, Fondaparinux -- Dosage and administration, Venous thrombosis -- Risk factors -- Prevention, Biological sciences
Abstract

Background Lower limb trauma requiring immobilization is a significant contributor to overall venous thromboembolism (VTE) burden. The clinical effectiveness of thromboprophylaxis for this indication and the optimal agent strategy are still a matter of debate. Our main objective was to assess the efficacy of pharmacological thromboprophylaxis to prevent VTE in patients with isolated temporary lower limb immobilization after trauma. We aimed to estimate and compare the clinical efficacy and the safety of the different thromboprophylactic treatments to determine the best strategy. Methods and findings We conducted a systematic review and a Bayesian network meta-analysis (NMA) including all available randomized trials comparing a pharmacological thromboprophylactic treatment to placebo or to no treatment in patients with leg immobilization after trauma. We searched Medline, Embase, and Web of Science until July 2021. Only RCT or observational studies with analysis of confounding factors including adult patients requiring temporary immobilization for an isolated lower limb injury treated conservatively or surgically and assessing pharmacological thromboprophylactic agents or placebo or no treatment were eligible for inclusion. The primary endpoint was the incidence of major VTE (proximal deep vein thrombosis, symptomatic VTE, and pulmonary embolism-related death). We extracted data according to Preferred Reporting Items for Systematic Reviews and Meta-analyses for NMA and appraised selected trials with the Cochrane review handbook. Fourteen studies were included (8,198 patients). Compared to the control group, rivaroxaban, fondaparinux, and low molecular weight heparins were associated with a significant risk reduction of major VTE with an odds ratio of 0.02 (95% credible interval (CrI) 0.00 to 0.19), 0.22 (95% CrI 0.06 to 0.65), and 0.32 (95% CrI 0.15 to 0.56), respectively. No increase of the major bleeding risk was observed with either treatment. Rivaroxaban has the highest likelihood of being ranked top in terms of efficacy and net clinical benefit. The main limitation is that the network had as many indirect comparisons as direct comparisons. Conclusions This NMA confirms the favorable benefit/risk ratio of thromboprophylaxis for patients with leg immobilization after trauma with the highest level of evidence for rivaroxaban. Trial registration PROSPERO CRD42021257669., Author(s): D. Douillet 1,2,3,*, C. Chapelle 4, E. Ollier 4,5, P. Mismetti 3,4, P.-M. Roy 1,2,3, S. Laporte 3,4 Introduction Background Patients with an isolated lower limb trauma requiring immobilization [...]

Published
2022
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30. How does the application of surgical components in enhanced recovery programs for colorectal surgery change over time?

Author

Alfonsi, P., Andre, A., Atger, J., Auvray, S., Bongiovanni, J.P., Boumadani, M., Bozio, G., Brek, A., Catinois, M.L., Chambirer, G., Chokairi, S., Chopin Laly, X., Cotte, E., De la Fontaine, C., Denet, C., Dileon, S., Douard, R., Dupré, A., Fernoux, Ph, Gergeanu, S., Gignoux, B., Hail, K., Joris, J., Laporte, S., Leporrier, J., Mauvais, F., Meillat, H., Michaud, Ph, Mor Martinez, C., Ostermann Bucher, S., Peluchon, Ph, Pichot-Delahaye, V., Plard, L., Raspado, O., Regimbeau, J.M., Riboud, R., Tavernier, M., Tete, B., Thievenaz, R., Venara, A., Voilin, C., Vuagnat, C., Veziant, Julie, Leonard, Daniel, Pereira, Bruno, and Slim, Karem

Published
2018
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32. OC 60.3 Prevention of Hemorrhage after Implantation of Mechanical Circulatory Support with a Purified Von Willebrand Factor Concentrate: Results of the Early Terminated Randomized Controlled PHAM Trial

Author

Rauch, A., primary, Lebreton, G., additional, Moussa, M., additional, Vincentelli, A., additional, Flecher, E., additional, Bouchot, O., additional, Dambrin, C., additional, Rozec, B., additional, Barandon, L., additional, Jeanpierre, E., additional, Ajzenberg, N., additional, Repessé, Y., additional, De Maistre, E., additional, Boissier, E., additional, Smadja, D., additional, Nedelec-Gac, F., additional, Voisin, S., additional, Laporte, S., additional, Labreuche, J., additional, and Susen, S., additional

Published
2023
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34. LB 02.2 Prevention of Symptomatic Venous Thromboembolism with LowMolecular-Weight Heparin in Hospitalized Older Adult Medical Patients: A Randomized Placebo-Controlled Trial

Author

Mottier, D., primary, Girard, P., additional, Couturaud, F., additional, Le Moigne, E., additional, Paleiron, N., additional, Guellec, D., additional, Sanchez, O., additional, Cogulet, V., additional, Laporte, S., additional, Marhic, G., additional, Mismetti, P., additional, Presles, E., additional, Robert-Ebadi, H., additional, Mahe, I., additional, Plaisance, L., additional, Reny, J., additional, Righini, M., additional, and Le Gal, G., additional

Published
2023
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35. Thrombolytiques

Author

Bennis, Y., primary, Bricca, G., additional, Laporte, S., additional, and Mismetti, P., additional

Published
2020
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38. Management of antiplatelet therapy in patients undergoing elective invasive procedures. Proposals from the French Working Group on perioperative haemostasis (GIHP) and the French Study Group on thrombosis and haemostasis (GFHT). In collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR)

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Godier, Anne, Fontana, Pierre, Motte, Serge, Steib, Annick, Bonhomme, Fanny, Schlumberger, Sylvie, Lecompte, Thomas, Rosencher, Nadia, Susen, Sophie, Vincentelli, André, Gruel, Yves, Albaladejo, Pierre, and Collet, Jean-Philippe

Published
2018
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40. Management of antiplatelet therapy in patients undergoing elective invasive procedures: Proposals from the French Working Group on perioperative hemostasis (GIHP) and the French Study Group on thrombosis and hemostasis (GFHT). In collaboration with the French Society for Anesthesia and Intensive Care (SFAR)

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Godier, Anne, Fontana, Pierre, Motte, Serge, Steib, Annick, Bonhomme, Fanny, Schlumberger, Sylvie, Lecompte, Thomas, Rosencher, Nadia, Susen, Sophie, Vincentelli, André, Gruel, Yves, Albaladejo, Pierre, and Collet, Jean-Philippe

Published
2018
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41. The HighNESS Project at the European Spallation Source: Current Status and Future Perspectives

Author

Santoro, V., primary, Andersen, K. H., additional, Bentley, P., additional, Bernasconi, M., additional, Bertelsen, M., additional, Beßler, Y., additional, Bianchi, A., additional, Brys, T., additional, Campi, D., additional, Chambon, A., additional, Czamler, V., additional, Di Julio, D. D., additional, Dian, E., additional, Dunne, K., additional, Ferreira, M. J., additional, Fierlinger, P., additional, Friman-Gayer, U., additional, Folsom, B. T., additional, Gaye, A., additional, Gorini, G., additional, Happe, C., additional, Holl, M., additional, Kamyshkov, Y., additional, Kittelmann, T., additional, Klinkby, E. B., additional, Kolevatov, R., additional, Laporte, S. I., additional, Lauritzen, B., additional, Marquez Damian, J. I., additional, Meirose, B., additional, Mezei, F., additional, Milstead, D., additional, Muhrer, G., additional, Neshvizhevsky, V., additional, Rataj, B., additional, Rizzi, N., additional, Rosta, L., additional, Samothrakitis, S., additional, Schober, H., additional, Selknaes, J. R., additional, Silverstein, S., additional, Strobl, M., additional, Strothmann, M., additional, Takibayev, A., additional, Wagner, R., additional, Willendrup, P., additional, Xu, S., additional, Yiu, S. C., additional, Zanini, L., additional, and Zimmer, O., additional

Published
2023
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47. The HighNESS Project at the European Spallation Source: Current Status and Future Perspectives

Author

Santoro, V., Andersen, K. H., Bentley, P., Bernasconi, M., Bertelsen, M., Beßler, Y., Bianchi, A., Brys, T., Campi, D., Chambon, A., Czamler, V., Di Julio, D. D., Dian, E., Dunne, K., Ferreira, M. J., Fierlinger, P., Friman-Gayer, U., Folsom, B. T., Gaye, A., Gorini, G., Happe, C., Holl, M., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Marquez Damian, J. I., Meirose, B., Mezei, F., Milstead, D., Muhrer, G., Neshvizhevsky, V., Rataj, B., Rizzi, N., Rosta, L., Samothrakitis, S., Schober, H., Selknaes, J. R., Silverstein, S., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Zanini, L., Zimmer, O., Santoro, V., Andersen, K. H., Bentley, P., Bernasconi, M., Bertelsen, M., Beßler, Y., Bianchi, A., Brys, T., Campi, D., Chambon, A., Czamler, V., Di Julio, D. D., Dian, E., Dunne, K., Ferreira, M. J., Fierlinger, P., Friman-Gayer, U., Folsom, B. T., Gaye, A., Gorini, G., Happe, C., Holl, M., Kamyshkov, Y., Kittelmann, T., Klinkby, E. B., Kolevatov, R., Laporte, S. I., Lauritzen, B., Marquez Damian, J. I., Meirose, B., Mezei, F., Milstead, D., Muhrer, G., Neshvizhevsky, V., Rataj, B., Rizzi, N., Rosta, L., Samothrakitis, S., Schober, H., Selknaes, J. R., Silverstein, S., Strobl, M., Strothmann, M., Takibayev, A., Wagner, R., Willendrup, P., Xu, S., Yiu, S. C., Zanini, L., and Zimmer, O.

Abstract

The European Spallation Source (ESS), presently under construction in Lund, Sweden, is a multidisciplinary international laboratory that, once completed at full specifications, will operate the world’s most powerful pulsed neutron source. Supported by a 3 M Euro Research and Innovation Action within the European Union Horizon 2020 program, a design study (HighNESS) is now underway to develop a second neutron source located below the spallation target. Compared to the first source, which is located above the spallation target and designed for high cold and thermal brightness, the new source is being optimized to deliver higher intensity and a shift to longer wavelengths in the spectral regions of cold neutrons (CNs) (2 to 20 Å), very cold neutrons (VCNs) (10 to 120 Å), and ultracold neutrons (UCNs) (>500 Å). The second source consists of a large liquid deuterium moderator to deliver CNs and serve secondary VCN and UCN sources, for which different options are under study. These new sources will boost several areas of condensed matter research and will provide unique opportunities in fundamental physics. The HighNESS project is now entering its last year, and we are working toward the Conceptual Design Report of the ESS upgrade. In this paper, results obtained in the first 2 years, ongoing developments, and future perspectives are described.

Published
2023

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