Search

Your search keyword '"Langeron, Olivier"' showing total 521 results
Start Over Author "Langeron, Olivier"
521 results on '"Langeron, Olivier"'

3. Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial

Author

Bouglé, Adrien, Tuffet, Sophie, Federici, Laura, Leone, Marc, Monsel, Antoine, Dessalle, Thomas, Amour, Julien, Dahyot-Fizelier, Claire, Barbier, François, Luyt, Charles-Edouard, Langeron, Olivier, Cholley, Bernard, Pottecher, Julien, Hissem, Tarik, Lefrant, Jean-Yves, Veber, Benoit, Legrand, Matthieu, Demoule, Alexandre, Kalfon, Pierre, Constantin, Jean-Michel, Rousseau, Alexandra, Simon, Tabassome, and Foucrier, Arnaud

Published
2022
Full Text
View/download PDF

4. Development and validation of a pre-hospital “Red Flag” alert for activation of intra-hospital haemorrhage control response in blunt trauma

Author

Hamada, Sophie Rym, Rosa, Anne, Gauss, Tobias, Desclefs, Jean-Philippe, Raux, Mathieu, Harrois, Anatole, Follin, Arnaud, Cook, Fabrice, Boutonnet, Mathieu, the Traumabase® Group, Attias, Arie, Ausset, Sylvain, Dhonneur, Gilles, Langeron, Olivier, Paugam-Burtz, Catherine, Pirracchio, Romain, Riou, Bruno, de St Maurice, Guillaume, Vigué, Bernard, Rouquette, Alexandra, and Duranteau, Jacques

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Hematology, Clinical Research, Physical Injury - Accidents and Adverse Effects, Good Health and Well Being, Adult, Blood Transfusion, Chi-Square Distribution, Cohort Studies, Emergency Medical Services, Female, Hemorrhage, Humans, Injury Severity Score, Lactic Acid, Male, Middle Aged, Paris, Prospective Studies, ROC Curve, Registries, Retrospective Studies, Simplified Acute Physiology Score, Statistics, Nonparametric, Wounds, Nonpenetrating, Traumabase® Group, Anticipation, Organization, Protocol, Severe haemorrhage, Severe trauma, Medical and Health Sciences, Emergency & Critical Care Medicine, Biomedical and clinical sciences, Health sciences
Abstract

BackgroundHaemorrhagic shock is the leading cause of early preventable death in severe trauma. Delayed treatment is a recognized prognostic factor that can be prevented by efficient organization of care. This study aimed to develop and validate Red Flag, a binary alert identifying blunt trauma patients with high risk of severe haemorrhage (SH), to be used by the pre-hospital trauma team in order to trigger an adequate intra-hospital standardized haemorrhage control response: massive transfusion protocol and/or immediate haemostatic procedures.MethodsA multicentre retrospective study of prospectively collected data from a trauma registry (Traumabase®) was performed. SH was defined as: packed red blood cell (RBC) transfusion in the trauma room, or transfusion ≥ 4 RBC in the first 6 h, or lactate ≥ 5 mmol/L, or immediate haemostatic surgery, or interventional radiology and/or death of haemorrhagic shock. Pre-hospital characteristics were selected using a multiple logistic regression model in a derivation cohort to develop a Red Flag binary alert whose performances were confirmed in a validation cohort.ResultsAmong the 3675 patients of the derivation cohort, 672 (18%) had SH. The final prediction model included five pre-hospital variables: Shock Index ≥ 1, mean arterial blood pressure ≤ 70 mmHg, point of care haemoglobin ≤ 13 g/dl, unstable pelvis and pre-hospital intubation. The Red Flag alert was triggered by the presence of any combination of at least two criteria. Its predictive performances were sensitivity 75% (72-79%), specificity 79% (77-80%) and area under the receiver operating characteristic curve 0.83 (0.81-0.84) in the derivation cohort, and were not significantly different in the independent validation cohort of 2999 patients.ConclusionThe Red Flag alert developed and validated in this study has high performance to accurately predict or exclude SH.

Published
2018

5. Correction to: Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial

Author

Bouglé, Adrien, Tuffet, Sophie, Federici, Laura, Leone, Marc, Monsel, Antoine, Dessalle, Thomas, Amour, Julien, Dahyot-Fizelier, Claire, Barbier, François, Luyt, Charles-Edouard, Langeron, Olivier, Cholley, Bernard, Pottecher, Julien, Hissem, Tarik, Lefrant, Jean-Yves, Veber, Benoit, Legrand, Matthieu, Demoule, Alexandre, Kalfon, Pierre, Constantin, Jean-Michel, Rousseau, Alexandra, Simon, Tabassome, and Foucrier, Arnaud

Published
2022
Full Text
View/download PDF

6. Intrahospital trauma flowcharts — Cognitive aids for intrahospital trauma management from the French Society of Anaesthesia and Intensive Care Medicine (SFAR) and the French Society of Emergency Medicine (SFMU)

Author

Gauss, Tobias, Quintard, Hervé, Bijok, Benjamin, Bouhours, Guillaume, Clavier, Thomas, Cook, Fabrice, de Courson, Hugues, David, Jean-Stéphane, Duracher-Gout, Caroline, Garrigue, Delphine, Geeraerts, Thomas, Hamada, Sophie, Joannes-Boyau, Olivier, Jouffroy, Romain, Lamblin, Antoine, Langeron, Olivier, Lanot, Pierre, Lasocki, Sigismond, Leone, Marc, Mirek, Sébastien, Muller, Laurent, Pasquier, Pierre, Prunet, Bertrand, Perbet, Sébastien, Raux, Mathieu, Richards, Justin, Roger, Claire, Roquilly, Antoine, Weiss, Emmanuel, Bouzat, Pierre, and Pottecher, Julien

Published
2022
Full Text
View/download PDF

8. Clinical outcome of wild-type AmpC-producing Enterobacterales infection in critically ill patients treated with β-lactams: a prospective multicenter study

Author

Mounier, Roman, Le Guen, Ronan, Woerther, Paul-Louis, Nacher, Mathieu, Bonnefon, Clément, Mongardon, Nicolas, Langeron, Olivier, Levesque, Eric, Couffin, Séverine, Houcke, Stéphanie, Wolff, Michel, Roujansky, Ariane, Schimpf, Caroline, Mekontso Dessap, Armand, Cook, Fabrice, Razazi, Keyvan, and Kallel, Hatem

Published
2022
Full Text
View/download PDF

9. The hip fracture surgery in elderly patients (HIPELD) study to evaluate xenon anaesthesia for the prevention of postoperative delirium: a multicentre, randomized clinical trial

Author

Coburn, M, Sanders, RD, Maze, M, Nguyên-Pascal, M-L, Rex, S, Garrigues, B, Carbonell, JA, Garcia-Perez, ML, Stevanovic, A, Kienbaum, P, Neukirchen, M, Schaefer, MS, Borghi, B, van Oven, H, Tognù, A, Tmimi, L Al, Eyrolle, L, Langeron, O, Capdevila, X, Arnold, GM, Schaller, M, Rossaint, R, Investigators, HIPELD Study, Coburn, Mark, Rossaint, Rolf, Stevanovic, Ana, Stoppe, Christian, Fahlenkamp, Astrid, Felzen, Marc, Knobe, Mathias, Sanders, Robert D, Maze, Mervyn, Nguyên-Pascal, My-Liên, Schaller, Manuella, Garrigues, Beatriz, Carbonell, José Antonio, Garcia-Perez, Marisa Luisa, Belda, Francisco J, Soro, Marina, Ferrando, C, León, Irene, Hernadez, J, Borghi, Battista, van Oven, Hanna, Tognù, Andrea, Guglielmetti, Aurora, Rossi, Barbara, Fini, Greta, Gallerani, Pina, Kienbaum, Peter, Neukirchen, Martin, Schaefer, Maximilian Sebastian, Bastin, Bea, Kuschka, Dina, Eisenach, Thorsten, Gaza, Nina, Rex, Steffen, tmimi, Layth Al, Devroe, Sarah, Van de Velde, Marc, Eyrolle, Luc, Jacquinot, Patrick, Rosencher, Nadia, Langeron, Olivier, Roche, Sabine, Paries, Marie, Capdevila, Xavier, Arnold, Glenn, Graham, Benjamin, Doyle, Patrick, Albaladejo, P, Minville, Vincent, Ferré, Fabrice, and Kunitz, Oliver

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Mental Health, Patient Safety, Physical Injury - Accidents and Adverse Effects, Osteoporosis, Clinical Research, Rehabilitation, Clinical Trials and Supportive Activities, Aging, 6.4 Surgery, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Aged, Aged, 80 and over, Anesthesia, Inhalation, Anesthetics, Inhalation, Emergence Delirium, Female, Hip Fractures, Humans, Incidence, Male, Orthopedic Procedures, Prospective Studies, Sevoflurane, Treatment Outcome, Xenon, anaesthesia, general, aged, delirium, hip fractures, xenon, HIPELD Study Investigators, anaesthesia, general, Anesthesiology, Clinical sciences
Abstract

BACKGROUND:Postoperative delirium occurs frequently in elderly hip fracture surgery patients and is associated with poorer overall outcomes. Because xenon anaesthesia has neuroprotective properties, we evaluated its effect on the incidence of delirium and other outcomes after hip fracture surgery. METHODS:This was a phase II, multicentre, randomized, double-blind, parallel-group, controlled clinical trial conducted in hospitals in six European countries (September 2010 to October 2014). Elderly (≥75yr-old) and mentally functional hip fracture patients were randomly assigned 1:1 to receive either xenon- or sevoflurane-based general anaesthesia during surgery. The primary outcome was postoperative delirium diagnosed through postoperative day 4. Secondary outcomes were delirium diagnosed anytime after surgery, postoperative sequential organ failure assessment (SOFA) scores, and adverse events (AEs). RESULTS:Of 256 enrolled patients, 124 were treated with xenon and 132 with sevoflurane. The incidence of delirium with xenon (9.7% [95% CI: 4.5 -14.9]) or with sevoflurane (13.6% [95% CI: 7.8 -19.5]) were not significantly different (P=0.33). Overall SOFA scores were significantly lower with xenon (least-squares mean difference: -0.33 [95% CI: -0.60 to -0.06]; P=0.017). For xenon and sevoflurane, the incidence of serious AEs and fatal AEs was 8.0% vs 15.9% (P=0.05) and 0% vs 3.8% (P=0.06), respectively. CONCLUSIONS:Xenon anaesthesia did not significantly reduce the incidence of postoperative delirium after hip fracture surgery. Nevertheless, exploratory observations concerning postoperative SOFA-scores, serious AEs, and deaths warrant further study of the potential benefits of xenon anaesthesia in elderly hip fracture surgery patients. CLINICAL TRIAL REGISTRATION:EudraCT 2009-017153-35; ClinicalTrials.gov NCT01199276.

Published
2018

10. A year in review in Minerva Anestesiologica 2023: anesthesia, analgesia, and perioperative medicine

Author

CAVALIERE, Franco, primary, ALLEGRI, Massimo, additional, APAN, Alparslan, additional, BRAZZI, Luca, additional, CARASSITI, Massimiliano, additional, COHEN, Edmond, additional, DI MARCO, Pierangelo, additional, LANGERON, Olivier, additional, ROSSI, Marco, additional, SPIETH, Peter, additional, TURNBULL, David, additional, and WEBER, Frank, additional

Published
2024
Full Text
View/download PDF

12. Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study

Author

JUVIN, Charles, SCHOELL, Thibault, D'Alessandro, Cosimo, MARIN, Sofica, NARDONE, Nathalie, DEMONDION, Pierre, MEYER, Horacio, BOUNADER, Karl, MOIROUX, Alexander, AKAMKAM, Ali, FADEL, Guillaume, RANDRIANALISOA, Erwan, CUSQUEL, Sébastien, LE GLOAHEC, Patrice, HIRSCHAUER, Elisabeth, MUSQUET, Fabrice, Jego, Pierre-Marie, Guedes, Hélène, Roy, Théophile, Mercereau, Lina, Corvol, Emmanuel, Laboure, Anne, Vilanove, Flore, Peperoni, Marco, Machado, Dariène, Sely, Aly, Fortanier, Marion, Gantois, Séverine, Tran, Emilie, Bosq, Elisabeth, Fontanier, Aurélie, Morin, Alice, Cousin, Jocelyne, Bovagnet, Stéphanie, Luyt, Charles Edouard, Hekimian, Guillaume, Brechot, Nicolas, Pineton de Chambrun, Marc, Desnos, Cyrielle, Chomeloux, Juliette, Arzoine, Jeremy, Guerin, Emmanuelle, Monsel, Antoine, Voiriot, Guillaume, Levy, David, Baron, Elodie, Beurton, Alexandra, Chommeloux, Juliette, Paris, Meng, Nemlaghi, Safaa, Bay, Pierre, Demoule, Alexandre, Guidet, Bertrand, Constantin, Jean Michel, Fartoukh, Muriel, Dres, Martin, Nataf, Patrick, Franchineau, Guillaume, Le Fevre, Lucie, Raffoul, Richard, Alkhoder, Soleiman, Ghodbane, Walid, Pisani, Angelo, Braham, Wael, Bessem Gara, Ali, MORDANT, Pierre, CASTIER, Yves-Hervé, de MONTMOLLIN, Etienne, BOUADMA, Lila, TIMSIT, Jean-François, Langeron, Olivier, de Roux, Quentin, Alessandri, Claire, Arminot-Frémaux, Margot, Clariot, Simon, Dessalle, Thomas, Kudela, Agathe, Ly, André, Meffert, Arnaud, Skripkina, Elena, Fiore, Antonio, Radu, Costin, Dupuy-Montbrun, Eleonora, Latremouille, Christian, Mercier, Olaf, Deleuze, Philippe, STEPHAN, François, Duranteau, Jacques, Richard, Christian, Werner, Marie, Teboul, Jean-Louis, Monnet, Xavier, Debbagh, Hassan, Chapelier, Alain, De Wolf, Julien, Glorion, Matthieu, Pricopi, Ciprian, Cassiano, Francesco, Jacquemin, Sébastien, Tachon, Guillaume, Parquin, François, Zuber, Benjamin, Carriou, Alain, Mira, Jean-Paul, Charpentier, Julien, Pene, Frederic, Nguyen, Lee, Voicu, Sébastian, Deye, Nicolas, Malissin, Isabelle, Sutterlin, Laetitia, Naim, Giulia, Pépin-Lehalleur, Adrien, Mrad, Aymen, Ekhérian, Jean-Michel, Nguyen, Philippe, Sidéris, Georgios, Vodovar, Dominique, Grant, Caroline, Arcelli, Mattéo, Copie, Alban, Errabih, Zaccaria, Gonde, Antoine, Magalhaes, Adèle, Meurisse, Edouard, Nitenberg, Kiyoko, Perault, Arthur, Perrin, Lucile, Renaux, Maxime, Marqué, Sophie, Ensenyat-Martin, Luis, Delpierre, Eric, Duprey, Matthieu, da Silva, Daniel, Verdière, Bruno, Amour, Julien, Clément, Marina, Ollivier, Yves, Morichau-Beauchant, Tristan, Daviaud, Fabrice, Le Breton, Camille, Freita-Ramos, Santiago, Amouretti, Marc, Billiet, Pierre Antoine, Dao, Myriam, Dumont, Louis Marie, Federici, Laura, Gaborieau, Baptiste, Postel-Vinay, Pierre, Vuillard, Constance, Zucman, Noémie, Dreyfuss, Didier, Ricard, Jean Damien, Roux, Damien, Lebreton, Guillaume, Schmidt, Matthieu, Ponnaiah, Maharajah, Folliguet, Thierry, Para, Marylou, Guihaire, Julien, Lansac, Emmanuel, Sage, Edouard, Cholley, Bernard, Mégarbane, Bruno, Cronier, Pierrick, Zarka, Jonathan, Da Silva, Daniel, Besset, Sebastien, Lacombat, Igor, Mongardon, Nicolas, Cerf, Charles, Saiydoun, Gabriel, Sonneville, Romain, Chiche, Jean-Daniel, Longrois, Dan, Combes, Alain, and Leprince, Pascal

Published
2021
Full Text
View/download PDF

13. Withholding and withdrawal of life-sustaining therapy in 8569 trauma patients: A multicentre, analytical registry study

Author

Haddam, Malik, Kubacsi, Laura, Hamada, Sophie, Harrois, Anatole, James, Arthur, Langeron, Olivier, Boutonnet, Mathieu, Holleville, Mathilde, Garrigue, Delphine, Leclercq, Marion, Hanouz, Jean-Luc, Pottecher, Julien, Audibert, Gérard, Cardinale, Mickael, Vinour, Hélène, Zieleskiewicz, Laurent, Resseguier, Noemie, and Leone, Marc

Published
2022
Full Text
View/download PDF

16. Guidelines: Anaesthesia in the context of COVID-19 pandemic

Author

Velly, Lionel, Gayat, Etienne, Quintard, Hervé, Weiss, Emmanuel, De Jong, Audrey, Cuvillon, Philippe, Audibert, Gérard, Amour, Julien, Beaussier, Marc, Biais, Matthieu, Bloc, Sébastien, Bonnet, Marie Pierre, Bouzat, Pierre, Brezac, Gilles, Dahyot-Fizelier, Claire, Dahmani, Souhayl, de Queiroz, Mathilde, Di Maria, Sophie, Ecoffey, Claude, Futier, Emmanuel, Geeraerts, Thomas, Jaber, Haithem, Heyer, Laurent, Hoteit, Rim, Joannes-Boyau, Olivier, Kern, Delphine, Langeron, Olivier, Lasocki, Sigismond, Launey, Yoan, le Saché, Frederic, Lukaszewicz, Anne Claire, Maurice-Szamburski, Axel, Mayeur, Nicolas, Michel, Fabrice, Minville, Vincent, Mirek, Sébastien, Montravers, Philippe, Morau, Estelle, Muller, Laurent, Muret, Jane, Nouette-Gaulain, Karine, Orban, Jean Christophe, Orliaguet, Gilles, Perrigault, Pierre François, Plantet, Florence, Pottecher, Julien, Quesnel, Christophe, Reubrecht, Vanessa, Rozec, Bertrand, Tavernier, Benoit, Veber, Benoit, Veyckmans, Francis, Charbonneau, Hélène, Constant, Isabelle, Frasca, Denis, Fischer, Marc-Olivier, Huraux, Catherine, Blet, Alice, and Garnier, Marc

Published
2020
Full Text
View/download PDF

19. Lung Ultrasound Score on Postoperative Day 1 Is Predictive of the Occurrence of Pulmonary Complications after Major Abdominal Surgery: A Multicenter Prospective Observational Study

Author

Boussier, Jeremy, primary, Lemasle, Aymeric, additional, Hantala, Nicolas, additional, Scatton, Olivier, additional, Vaillant, Jean-Christophe, additional, Paye, François, additional, Langeron, Olivier, additional, Lescot, Thomas, additional, Quesnel, Christophe, additional, Verdonk, Franck, additional, Eyraud, Daniel, additional, Sitbon, Alexandre, additional, Delorme, Louis, additional, and Monsel, Antoine, additional

Published
2023
Full Text
View/download PDF

21. Assessment of remifentanil for rapid sequence induction and intubation in patients at risk of pulmonary aspiration of gastric contents compared to rapid-onset paralytic agents: study protocol for a non-inferiority simple blind randomized controlled trial (the REMICRUSH study)

Author

Grillot, Nicolas, Garot, Matthias, Lasocki, Sigismond, Huet, Olivier, Bouzat, Pierre, Le Moal, Charlène, Oudot, Mathieu, Chatel-Josse, Nolwenn, El Amine, Younes, Danguy des Déserts, Marc, Bruneau, Nathalie, Cinotti, Raphael, David, Jean-Stéphane, Langeron, Olivier, Minville, Vincent, Tching-Sin, Martine, Faurel-Paul, Elodie, Lerebourg, Céline, Flattres-Duchaussoy, Delphine, Jobert, Alexandra, Asehnoune, Karim, Feuillet, Fanny, and Roquilly, Antoine

Published
2021
Full Text
View/download PDF

22. Complete percutaneous angio-guided approach using preclosing for venoarterial extracorporeal membrane oxygenation implantation and explantation in patients with refractory cardiogenic shock or cardiac arrest

Author

Martin-Tuffreau, Anne-Sophie, Bagate, François, Boukantar, Madjid, Saiydoun, Gabriel, Mangiameli, Andrea, Rostain, Laura, Mouillet, Gauthier, Fiore, Antonio, Langeron, Olivier, Mekontso-Dessap, Armand, Mongardon, Nicolas, Folliguet, Thierry, Teiger, Emmanuel, and Gallet, Romain

Published
2021
Full Text
View/download PDF

23. Microglial production of quinolinic acid as a target and a biomarker of the antidepressant effect of ketamine

Author

Verdonk, Franck, Petit, Anne-Cécile, Abdel-Ahad, Pierre, Vinckier, Fabien, Jouvion, Gregory, de Maricourt, Pierre, De Medeiros, Gabriela Ferreira, Danckaert, Anne, Van Steenwinckel, Juliette, Blatzer, Michael, Maignan, Anna, Langeron, Olivier, Sharshar, Tarek, Callebert, Jacques, Launay, Jean-Marie, Chrétien, Fabrice, and Gaillard, Raphael

Published
2019
Full Text
View/download PDF

24. Personalised mechanical ventilation tailored to lung morphology versus low positive end-expiratory pressure for patients with acute respiratory distress syndrome in France (the LIVE study): a multicentre, single-blind, randomised controlled trial

Author

Sophie, Cayot, Thomas, Godet, Renaud, Guerin, Camille, Verlac, Russel, Chabanne, Bernard, Cosserant, Raiko, Blondonnet, Alexandre, Lautrette, Nathanael, Eisenmann, Laurent, Muller, Pablo, Massanet, Caroline, Boutin, Saber, Barbar, Claire, Roger, Fouad, Belafia, Moussa, Cisse, Marion, Monnin, Matthieu, Conseil, Julie, Carr, Audrey, De Jong, Auguste, Dargent, Pascal, Andreu, Thomas, Lebouvrier, Yoann, Launey, Antoine, Roquilly, Raphael, Cinotti, Anne-Charlotte, Tellier, Mathilde, Barbaz, Benjamin, Cohen, Edouard, Lemarche, Pierre-Marie, Bertrand, Charlotte, Arberlot, Laurent, Zieleskiewicz, Emmanuelle, Hammad, Garry, Duclos, Calypso, Mathie, Herve, Dupont, Benoit, Veber, Jean-Christophe, Orban, Hervé, Quintard, Thomas, Rimmele, Julien, Crozon-Clauzel, Marinne, Le Core, Fabien, Grelon, Mona, Assefi, Frank, Petitas, Jerome, Morel, Serge, Molliex, Nanadougmar, Hadanou, Constantin, Jean-Michel, Jabaudon, Matthieu, Lefrant, Jean-Yves, Jaber, Samir, Quenot, Jean-Pierre, Langeron, Olivier, Ferrandière, Martine, Grelon, Fabien, Seguin, Philippe, Ichai, Carole, Veber, Benoit, Souweine, Bertrand, Uberti, Thomas, Lasocki, Sigismond, Legay, François, Leone, Marc, Eisenmann, Nathanael, Dahyot-Fizelier, Claire, Dupont, Hervé, Asehnoune, Karim, Sossou, Achille, Chanques, Gérald, Muller, Laurent, Bazin, Jean-Etienne, Monsel, Antoine, Borao, Lucile, Garcier, Jean-Marc, Rouby, Jean-Jacques, Pereira, Bruno, and Futier, Emmanuel

Published
2019
Full Text
View/download PDF

26. Effect of early use of noradrenaline on in-hospital mortality in haemorrhagic shock after major trauma: a propensity-score analysis

Author

Attias, Arie, Ausset, Sylvain, Boutonnet, Mathieu, Dhonneur, Gilles, Duranteau, Jacques, Langeron, Olivier, Mantz, Jean, Paugam-Burtz, Catherine, Pirracchio, Romain, Riou, Bruno, de St Maurice, Guillaume, Vigué, Bernard, Bertho, Kilian, Chollet-Xemard, Charlotte, Dolveck, François, Michelland, Laurianne, Reuter, Paul-Georges, Ricard-Hibon, Agnès, Richard, Olivier, Sapir, David, Vivien, Benoît, Gauss, T., Gayat, E., Harrois, A., Raux, M., Follin, A., Daban, J.-L., Cook, F., and Hamada, S.

Published
2018
Full Text
View/download PDF

27. Use of brain diffusion tensor imaging for the prediction of long-term neurological outcomes in patients after cardiac arrest: a multicentre, international, prospective, observational, cohort study

Author

Constantin, Jean-Michel, Chastre, Jean, Amour, Julien, Vezinet, Corine, Rouby, Jean-Jacques, Raux, Mathieu, Langeron, Olivier, Degos, Vincent, Bolgert, Francis, Weiss, Nicolas, Similowski, Thomas, Demoule, Alexandre, Duguet, Alexandre, Tollard, Eleonore, Veber, Benoit, Lotterie, Jean-Albert, SANCHEZ-PENA, Paola, Génestal, Michèle, Patassini, Mirko, Velly, Lionel, Perlbarg, Vincent, Boulier, Thomas, Adam, Nicolas, Delphine, Sebastien, Luyt, Charles-Edouard, Battisti, Valentine, Torkomian, Gregory, Arbelot, Charlotte, Chabanne, Russell, Jean, Betty, Di Perri, Carol, Laureys, Steven, Citerio, Giuseppe, Vargiolu, Alessia, Rohaut, Benjamin, Bruder, Nicolas, Girard, Nadine, Silva, Stein, Cottenceau, Vincent, Tourdias, Thomas, Coulon, Olivier, Riou, Bruno, Naccache, Lionel, Gupta, Rajiv, Benali, Habib, Galanaud, Damien, and Puybasset, Louis

Published
2018
Full Text
View/download PDF

32. Cathéters sciatiques: une alternative analgésique chez les patients diabétiques

Author

Schaeffer, Elodie, Saché, Frédéric, Bourron, Olivier, Collin, Elisabeth, Langeron, Olivier, and Birenbaum, Aurélie

Abstract

Les patients diabétiques ont des douleurs neuropathiques chroniques. L’objectif de notre étude était 1) d’évaluer la faisabilité d’une technique anesthésique par cathéter périnerveux sciatique, en service de diabétologie et 2) évaluer son efficacité. Une étude prospective, monocentrique, non randomisée a été menée pendant deux ans. Tous les patients diabétiques, en échec de traitement systémique optimisé, ont été inclus. Leur consentement écrit était recueilli. Des cathéters périnerveux sciatiques ont été posés sous échoguidage et la ropivacaïne était débutée. L’objectif principal était la douleur à J2. L’intensité de la douleur était mesurée par l’échelle numérique (EN). Les objectifs secondaires étaient le soulagement des patients, l’impact sur la qualité de vie et la consommation de morphine, évaluée à J0, J2, à l’ablation du cathéter et un mois après son ablation. La faisabilité a été évaluée pendant 1 an. Cinquante-cinq cathéters périnerveux ont été posés chez 32 patients. La durée médiane de jours de cathéter par patient était de 13 [4-23] jours. Aucune complication toxique ni infectieuse n’a été constatée. L’efficacité a été évaluée la deuxième année. Dix-sept cathéters ont été posés chez 12 patients: 83 % des patients avaient une EN ≤ 3 à J2. Pendant toute la durée du cathétérisme et jusqu’à un mois après l’ablation du cathéter, le soulagement des patients était ≥ 70 %. L’impact sur la qualité de vie était minime. La consommation de morphine diminuait à J2, à l’ablation du cathéter et un mois après son ablation. L’utilisation de cathéters périnerveux sciatique, comme technique analgésique alternative au sein d’un milieu extra chirurgical, chez des patients diabétiques douloureux chroniques, a été possible et efficace. Patients with diabetes mellitus have chronic neuropathic pain. The aim of our study was to 1) evaluate the feasibility of providing analgesia with a long-term sciatic perineural catheter in a medical unit for diabetic patients and 2) evaluate its effectiveness. A prospective, monocentric, non-randomized study was conducted over two years. All diabetic patients with an ineffective optimal systemic treatment were included. Written consent was obtained. Popliteal-sciatic nerve catheters were inserted under ultrasound guidance; ropivacaine was started. The primary endpoint was pain at Day 2. Pain intensity was measured using a numeric rating scale (NRS). Secondary endpoints were patient’s pain relief, the impact on quality of life, and morphine consumption, evaluated at Day 0, Day 2, at the time of catheter removal, and one month after catheter removal. Feasibility was evaluated over one year. Fifty-five perineural catheters were placed in 32 patients. The median duration of catheter placement across patients was 13 [4-23] days. No toxic or infectious complications were seen. Effectiveness was evaluated during the second year of the study. Seventeen catheters were placed in 12 patients; 83% of patients had a NRS score ≤3 at Day 2. More than 70% of patients experienced pain relief while the catheter was in place and at one month after its removal. The impact on quality of life was negligible. Morphine consumption was less on Day 2, at the time of catheter removal and one month after removal. The use of sciatic perineural catheters as an alternative analgesia technique in a non-surgical environment for diabetic patients with chronic pain was possible and effective.

Published
2024
Full Text
View/download PDF

36. A year in review in Minerva Anestesiologica 2022: anesthesia, analgesia, and perioperative medicine

Author

CAVALIERE, Franco, primary, ALLEGRI, Massimo, additional, APAN, Alparslan, additional, BRAZZI, Luca, additional, CARASSITI, Massimiliano, additional, COHEN, Edmond, additional, DI MARCO, Pierangelo, additional, LANGERON, Olivier, additional, ROSSI, Marco, additional, SPIETH, Peter, additional, TURNBULL, David, additional, and WEBER, Frank, additional

Published
2023
Full Text
View/download PDF

40. Invention of intensive care medicine by an anaesthesiologist: 70 years of progress from epidemics to resilience to exceptional healthcare crises

Author

Collange, Olivier, primary, Mongardon, Nicolas, additional, Allaouchiche, Bernard, additional, Miatello, Jordi, additional, Bouhemad, Bélaid, additional, Trouiller, Pierre, additional, Chousterman, Benjamin, additional, Launey, Yoann, additional, Mayeur, Nicolas, additional, Besnier, Emmanuel, additional, Constantin, Jean-Michel, additional, Langeron, Olivier, additional, Degos, Vincent, additional, Atchade, Enora, additional, Amathieu, Roland, additional, Morel, Jérôme, additional, Bounes, Fanny, additional, and Dahyot-Fizelier, Claire, additional

Published
2022
Full Text
View/download PDF

41. Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

Author

Kamilia, Chtara, Regaieg, Kais, Baccouch, Najeh, Chelly, Hedi, Bahloul, Mabrouk, Bouaziz, Mounir, Jendoubi, Ali, Abbes, Ahmed, Belhaouane, Houda, Nasri, Oussama, Jenzri, Layla, Ghedira, Salma, Houissa, Mohamed, Belkadi, Kamal, Harti, Youness, Nsiri, Afak, Khaleq, Khalid, Hamoudi, Driss, Harrar, Rachid, Thieffry, Camille, Wallet, Frédéric, Parmentier-Decrucq, Erika, Favory, Raphaël, Mathieu, Daniel, Poissy, Julien, Lafon, Thomas, Vignon, Philippe, Begot, Emmanuelle, Appert, Alexandra, Hadj, Mathilde, Claverie, Paul, Matt, Morgan, Barraud, Olivier, François, Bruno, Jamoussi, Amira, Jazia, Amira Ben, Marhbène, Takoua, Lakhdhar, Dhouha, Khelil, Jalila Ben, Besbes, Mohamed, Goutay, Julien, Blazejewski, Caroline, Joly-Durand, Isabelle, Pirlet, Isabelle, Weillaert, Marie Pierre, Beague, Sebastien, Aziz, Soufi, Hafiane, Reda, Hattabi, Khalid, Bouhouri, Mohamed Aziz, Hammoudi, Driss, Fadil, Abdelaziz, Harrar, Rachid Al, Zerouali, Khalid, Medhioub, Fatma Kaaniche, Allela, Rania, Algia, Najla Ben, Cherif, Samar, Slaoui, Mohamed Taoufik, Boubia, Souhail, Hafiani, Y., Khaoudi, A., Cherkab, R., Elallam, W., Elkettani, C., Barrou, L., Ridaii, M., Mehdi, Rihi El, Schimpf, Caroline, Mizrahi, Assaf, Pilmis, Benoît, Le Monnier, Alban, Tiercelet, Kelly, Cherin, Mélanie, Bruel, Cédric, Philippart, Francois, Bailly, Sébastien, Lucet, Jc, Lepape, Alain, L’hériteau, François, Aupée, Martine, Bervas, Caroline, Boussat, Sandrine, Berger-Carbonne, Anne, Machut, Anaïs, Savey, Anne, Timsit, Jean-François, Razazi, Keyvan, Rosman, Jérémy, de Prost, Nicolas, Carteaux, Guillaume, Jansen, Chloe, Decousser, Jean Winoc, Brun-Buisson, Christian, Dessap, Armand Mekontso, M’rad, Aymen, Ouali, Zouhour, Barghouth, Manel, Kouatchet, Achille, Mahieu, Rafael, Weiss, Emmanuel, Schnell, David, Zahar, Jean-Ralph, Artiguenave, Margaux, Sophie, Paktoris-Papine, Espinasse, Florence, Sayed, Faten El, Dinh, Aurélien, Charron, Cyril, Geri, Guillaume, Vieillard-Baron, Antoine, Repessé, Xavier, Kallel, Hatem, Mayence, Claire, Houcke, Stéphanie, Guegueniat, Pascal, Hommel, Didier, Dhifaoui, Kaouther, Hajjej, Zied, Fatnassi, Amira, Sellami, Walid, Labbene, Iheb, Ferjani, Mustapha, Dachraoui, Fahmi, Nakkaa, Sabrine, M’ghirbi, Abdelwaheb, Adhieb, Ali, Braiek, Dhouha Ben, Hraiech, Kmar, Ousji, Ali, Ouanes, Islem, Zaineb, Hammouda, Abdallah, Saousen Ben, Ouanes-Besbes, Lamia, Abroug, Fekri, Klein, Simon, Miquet, Mattéo, Thouret, Jean-Marc, Peigne, Vincent, Daban, Jean-Louis, Boutonnet, Mathieu, Lenoir, Bernard, Merhbene, Takoua, Derreumaux, Celine, Seguin, Thierry, Conil, Jean-Marie, Kelway, Charlotte, Blasco, Valery, Nafati, Cyril, Harti, Karim, Reydellet, Laurent, Albanese, Jacques, Aicha, Narjess Ben, Meddeb, Khaoula, Khedher, Ahmed, Ayachi, Jihene, Fraj, Nesrine, Sma, Nesrine, Chouchene, Imed, Boussarsar, Mohamed, Yedder, Soumaya Ben, Samoud, Walid, Radhouene, Bousselmi, Mariem, Bousselmi, Ammar, Asma, Cheikh, Asma Ben, Lakhal, Hend Ben, Khelfa, Messaouda, Hamdaoui, Yamina, Bouafia, Nabiha, Trampont, Timothée, Daix, Thomas, Legarçon, Vincent, Karam, Henri Hani, Pichon, Nicolas, Essafi, Fatma, Foudhaili, Nasreddine, Thabet, Hafedh, Blel, Youssef, Brahmi, Nozha, Ezzouine, Hanane, Kerrous, Mahmoud, Haoui, Saad El, Ahdil, Soufiane, Benslama, Abdellatif, Abidi, Khalid, Dendane, Tarek, Oussama, Ssouni, Belayachi, Jihane, Madani, Naoufal, Abouqal, Redouane, Zeggwagh, Amine Ali, Ghadhoune, Hatem, Chaari, Anis, Jihene, Guissouma, Allouche, Hend, Trabelsi, Insaf, Brahmi, Habib, Samet, Mohamed, Ghord, Hatem El, Habiba, Ben Sik Ali, Hajer, Nouira, Tilouch, Najla, Yaakoubi, Sondes, Jaoued, Oussama, Gharbi, Rim, Hassen, Mohamed Fekih, Elatrous, Souheil, Arcizet, Julien, Leroy, Bertrand, Abdulmalack, Caroline, Renzullo, Catherine, Hamet, Maël, Doise, Jean-Marc, Coutet, Jérôme, Cheikh, Chaigar Mohammed, Quechar, Zakaria, Joris, Magalie, Beauport, Dimitri Titeca, Kontar, Loay, Lebon, Delphine, Gruson, Bérengère, Slama, Michel, Marolleau, Jean-Pierre, Maizel, Julien, Gorham, Julie, Ameye, Lieveke, Berghmans, Thierry, Paesmans, Marianne, Sculier, Jean-Paul, Meert, Anne-Pascale, Guillot, Max, Ledoux, Marie-Pierre, Braun, Thierry, Maestraggi, Quentin, Michard, Baptiste, Castelain, Vincent, Herbrecht, Raoul, Schneider, Francis, Couffin, Severine, Lobo, David, Mongardon, Nicolas, Dhonneur, Gilles, Mounier, Roman, Le Borgne, Pierrick, Couraud, Sophie, Herbrecht, Jean-Etienne, Boivin, Alexandra, Lefebvre, François, Bilbault, Pascal, Zelmat, Setti-Aouicha, Batouche, Djamila-Djahida, Mazour, Fatima, Chaffi, Belkacem, Benatta, Nadia, Sik, Ali Habiba, Talik, I., Perrier, Maxime, Gouteix, Eliane, Koubi, Claude, Escavy, Annabelle, Guilbaut, Victoria, Fosse, Jean-Philippe, Jazia, Rahma Ben, Abdelghani, Ahmed, Cungi, Pierre-Julien, Bordes, Julien, Nguyen, Cédric, Pierrou, Candice, Cruc, Maximilien, Benois, Alain, Duprez, Frédéric, Bonus, Thierry, Cuvelier, Grégory, Ollieuz, Sandra, Machayekhi, Sharam, Paciorkowski, Frédéric, Reychler, Gregory, Coudroy, Remi, Thille, Arnaud W., Drouot, Xavier, Diaz, Véronique, Meurice, Jean-Claude, Robert, René, Turki, Olfa, Ben, Hmida Chokri, Assefi, Mona, Deransy, Romain, Brisson, Hélène, Monsel, Antoine, Conti, Filomena, Scatton, Olivier, Langeron, Olivier, Ghezala, Hassen Ben, Snouda, Salah, Ben, Chiekh Imen, Kaddour, Moez, Armel, Anwar, Youness, Lafrikh, Abdelhak, Bensaid, Youssef, Miloudi, Najib, Al Harrar, Mustapha, Amouzoun, Noufel, Mtioui, Mohamed, Zamd, Salma, El Khayat, Ghizlane, Medkouri, Mohamed, Benghanam, Benyounes, Ramdani, Montini, Florent, Moschietto, Sébastien, Gregoire, Emilien, Claisse, Guillaume, Guiot, Julien, Morimont, Philippe, Krzesinski, Jean-Marie, Mariat, Christophe, Lambermont, Bernard, Cavalier, Etienne, Delanaye, Pierre, Benbernou, Soumia, Ilies, Sofiane, Azza, Abdelkader, Bouyacoub, Khalida, Louail, Meriem, Mokhtari-Djebli, Houria, Arrestier, Romain, Daviaud, Fabrice, Francois, Xavier Laborne, Brocas, Elsa, Choukroun, Gérald, Peñuelas, Oscar, Lorente, José-Angel, Cardinal-Fernandez, Pablo, Rodriguez, José-Maria, Aramburu, José-Antonio, Esteban, Andres, Frutos-Vivar, Fernando, Bitker, Laurent, Costes, Nicolas, Le Bars, Didier, Lavenne, Franck, Devouassoux, Mojgan, Richard, Jean-Christophe, Mechati, Malika, Gainnier, Marc, Papazian, Laurent, Guervilly, Christophe, Garnero, Aude, Arnal, Jean Michel, Roze, Hadrien, Richard, Jean Christophe, Repusseau, Benjamin, Dewitte, Antoine, Joannes-Boyau, Olivier, Ouattara, Alexandre, Harbouze, Nadia, Amine, A. M., Olandzobo, A. G., Herbland, Alexandre, Richard, Marie, Girard, Nicolas, Lambron, Lucile, Lesieur, Olivier, Wainschtein, Sarah, Hubert, Sidonie, Hugues, Albane, Tran, Marc, Bouillard, Philippe, Loteanu, Vlad, Leloup, Maxime, Laurent, Alexandra, Lheureux, Florent, Prestifilippo, Alessia, Cruz, Martin Delgado Maria, Romain, Rigal, Antonelli, Massimo, Blanch, Torra Lluis, Bonnetain, Franck, Grazzia-Bocci, Maria, Mancebo, Jordi, Samain, Emmanuel, Paul, Hebert, Capellier, Gilles, Zavgorodniaia, Taissa, Soichot, Marion, Malissin, Isabelle, Voicu, Sebastian, Garçon, Pierre, Goury, Antoine, Kerdjana, Lamia, Deye, Nicolas, Bourgogne, Emmanuel, Megarbane, Bruno, Mejri, Olfa, Hmida, Marwa Ben, Tannous, Salma, Chevillard, Lucie, Labat, Laurence, Risede, Patricia, Fredj, Hana, Léger, Maxime, Brunet, Marion, Le Roux, Gaël, Boels, David, Lerolle, Nicolas, Farah, Souaad, Amiel-Niemann, Hélène, Kubis, Nathalie, Declèves, Xavier, Peyraux, Nicoals, Baud, Frederic, Serafini, Micaela, Alvarez, Jean-Claude, Heinzelman, Annette, Jozwiak, Mathieu, Millasseau, Sandrine, Teboul, Jean-Louis, Alphonsine, Jean-Emmanuel, Depret, François, Richard, Nathalie, Attal, Pierre, Richard, Christian, Monnet, Xavier, Chemla, Denis, Jerbi, Salma, Khedhiri, Wafa, Necib, Hatem, Scarfo, Paolo, Chevalier, Charles, Piagnerelli, Michael, Lafont, Alexandre, Galy, Antoine, Mancia, Claire, Zerhouni, Amel, Tabeliouna, Kheira, Gaja, Ali, Hamrouni, Bassem, Malouch, Abir, Fourati, Sami, Messaoud, Rihab, Zarrouki, Youssef, Ziadi, Amra, Rhezali, Manal, Zouizra, Zahira, Boumzebra, Drissi, Samkaoui, Mohamed Abdennasser, Brunet, Jennifer, Canoville, Bertrand, Verrier, Pierre, Ivascau, Calin, Seguin, Amélie, Valette, Xavier, Du Cheyron, Damien, Daubin, Cedric, Bougouin, Wulfran, Aissaoui, Nadia, Lamhaut, Lionel, Jost, Daniel, Maupain, Carole, Beganton, Frankie, Bouglé, Adrien, Dumas, Florence, Marijon, Eloi, Jouven, Xavier, Cariou, Alain, Poirson, Florent, Chaput, Ulriikka, Beeken, Thomas, Maxime, Leclerc, Haikel, Oueslati, Vodovar, Dominique, Chelly, Jonathan, Marteau, Philippe, Chocron, Richard, Juvin, Philippe, Loeb, Thomas, Adnet, Frederic, Lecarpentier, Eric, Riviere, Antoine, De Cagny, Bertand, Soupison, Thierry, Privat, Elodie, Escutnaire, Joséphine, Dumont, Cyrielle, Baert, Valentine, Vilhelm, Christian, Hubert, Hervé, Leteurtre, Stéphane, Fresco, Marion, Bubenheim, Michael, Beduneau, Gaetan, Carpentier, Dorothée, Grange, Steven, Artaud-Macari, Elise, Misset, Benoit, Tamion, Fabienne, Girault, Christophe, Dumas, Guillaume, Chevret, Sylvie, Lemiale, Virginie, Mokart, Djamel, Mayaux, Julien, Pène, Frédéric, Nyunga, Martine, Perez, Pierre, Moreau, Anne-Sophie, Bruneel, Fabrice, Vincent, François, Klouche, Kada, Reignier, Jean, Rabbat, Antoine, Azoulay, Elie, Frat, Jean-Pierre, Ragot, Stéphanie, Constantin, Jean-Michel, Prat, Gwenael, Mercat, Alain, Boulain, Thierry, Demoule, Alexandre, Devaquet, Jérôme, Nseir, Saad, Charpentier, Julien, Argaud, Laurent, Beuret, Pascal, Ricard, Jean-Damien, Teiten, Christelle, Marjanovic, Nicolas, Palamin, Nicola, L’Her, Erwan, Bailly, Arthur, Boisramé-Helms, Julie, Champigneulle, Benoit, Kamel, Toufik, Mercier, Emmanuelle, Le Thuaut, Aurélie, Lascarrou, Jean-Baptiste, Rolle, Amélie, De Jong, Audrey, Chanques, Gérald, Jaber, Samir, Hariri, Geoffroy, Baudel, Jean-Luc, Dubée, Vincent, Preda, Gabriel, Bourcier, Simon, Joffre, Jeremie, Bigé, Naïke, Ait-Oufella, Hafid, Maury, Eric, Mater, Houda, Merdji, Hamid, Grimaldi, David, Rousseau, Christophe, Mira, Jean-Paul, Chiche, Jean-Daniel, Sedghiani, Ines, Benabderrahim, A., Hamdi, Dhekra, Jendoubi, Asma, Cherif, Mohamed Ali, Hechmi, Youssef Zied El, Zouheir, Jerbi, Bagate, François, Bousselmi, Radhwen, Schortgen, Frédérique, Asfar, Pierre, Guérot, Emmanuel, Fabien, Grelon, Anguel, Nadia, Sigismond, Lasocki, Matthieu, Henry-Lagarrigue, Gonzalez, Frédéric, François, Legay, Guitton, Christophe, Schenck, Maleka, Jean-Marc, Doise, Dreyfuss, Didier, Radermacher, Peter, Frère, Antoine, Martin-Lefèvre, Laurent, Colin, Gwenhaël, Fiancette, Maud, Henry-Laguarrigue, Matthieu, Lacherade, Jean-Claude, Lebert, Christine, Vinatier, Isabelle, Yehia, Aihem, Joret, Aurélie, Menunier-Beillard, Nicolas, Benzekri-Lefevre, Dalila, Desachy, Arnaud, Bellec, Fréderic, Plantefève, Gaëtan, Quenot, Jean-Pierre, Meziani, Ferhat, Tavernier, Elsa, Ehrmann, Stephan, Chudeau, Nicolas, Raveau, Tommy, Moal, Valérie, Houillier, Pascal, Rouve, Emmanuelle, Lakhal, Karim, Gandonnière, Charlotte Salmon, Jouan, Youenn, Bodet-Contentin, Laetitia, Balmier, Adrien, Messika, Jonathan, De Montmollin, Etienne, Pouyet, Victorine, Sztrymf, Benjamin, Thiagarajah, Abirami, Roux, Damien, De Chambrun, Marc Pineton, Luyt, Charles-Edouard, Beloncle, François, Zapella, Nathalie, Ledochowsky, Stanislas, Terzi, Nicolas, Mazou, Jean-Marc, Sonneville, Romain, Paulus, Sylvie, Fedun, Yannick, Landais, Mickael, Raphalen, Jean-Herlé, Combes, Alain, Amoura, Zahir, Jacquemin, Aemilia, Guerrero, Felipe, Marcheix, Bertrand, Hernandez, Nicolas, Fourcade, Olivier, Georges, Bernard, Delmas, Clément, Makoudi, Sarah, Genton, Audrey, Bernard, Rémy, Lebreton, Guillaume, Amour, Julien, Mazet, Charlotte, Bounes, Fanny, Murat, Gurbuz, Cronier, Laure, Robin, Guillaume, Biendel, Caroline, Silva, Stein, Boubeche, Samia, Abriou, Caroline, Wurtz, Véronique, Scherrer, Vincent, Rey, Nathalie, Gastaldi, Gioia, Veber, Benoit, Doguet, Fabien, Gay, Arnaud, Dureuil, Bertrand, Besnier, Emmanuel, Rouget, Antoine, Gantois, Guillaume, Magalhaes, Eric, Wanono, Ruben, Smonig, Roland, Lermuzeaux, Mathilde, Lebut, Jordane, Olivier, Andremont, Dupuis, Claire, Radjou, Aguila, Mourvillier, Bruno, Neuville, Mathilde, D’ortho, Marie Pia, Bouadma, Lila, Rouvel-Tallec, Anny, Rudler, Marika, Weiss, Nicolas, Perlbarg, Vincent, Galanaud, Damien, Thabut, Dominique, Rachdi, Emna, Mhamdi, Ghada, Trifi, Ahlem, Abdelmalek, Rim, Abdellatif, Sami, Daly, Foued, Nasri, Rochdi, Tiouiri, Hanene, Lakhal, Salah Ben, Rousseau, Geoffroy, Asmolov, Romain, Grammatico-Guillon, Leslie, Auvet, Adrien, Laribi, Said, Garot, Denis, Dequin, Pierre François, Guillon, Antoine, Fergé, Jean-Louis, Abgrall, Gwénolé, Hinault, Ronan, Vally, Shazima, Roze, Benoit, Chaplain, Agathe, Chabartier, Cyrille, Savidan, Anne-Charlotte, Marie, Sabia, Cabie, Andre, Resiere, Dabor, Valentino, Ruddy, Mehdaoui, Hossein, Benarous, Lucas, Soda-Diop, Marième, Bouzana, Fouad, Perrin, Gilles, Bourenne, Jeremy, Eon, Béatrice, Lambert, Dominique, Trebuchon, Agnes, Poncelet, Géraldine, Le Bourgeois, Fleur, Michael, Levy, Camille, Guillot, Naudin, Jérôme, Deho, Anna, Dauger, Stéphane, Sauthier, Michaël, Bergeron-Gallant, Krystale, Emeriaud, Guillaume, Jouvet, Philippe, Tiebergien, Nicolas, Jacquet-Lagrèze, Matthias, Fellahi, Jean-Luc, Baudin, Florent, Essouri, Sandrine, Javouhey, Etienne, Guérin, Claude, Lampin, Marie, Mamouri, Ouardia, Devos, Patrick, Karaca-Altintas, Yasemin, Vinchon, Matthieu, Brossier, David, Eltaani, Redha, Teyssedre, Sonia, Sabine, Meyet, Bouchut, Jean-Christophe, Peguet, Olivier, Petitdemange, Lucie, Guilbert, Anne Sophie, Aoul, Nabil Tabet, Addou, Zakaria, Aouffen, Nabil, Anas, Benqqa, Kalouch, Samira, Yaqini, Khalid, Chlilek, Aziz, Abdou, Rchi, Gravellier, Perrine, Chantreuil, Julie, Travers, Nadine, Listrat, Antoine, Le Reun, Claire, Favrais, Geraldine, Coppere, Zoe, Blanot, Stéphane, Montmayeur, Juliette, Bronchard, Régis, Rolando, Stephane, Orliaguet, Gilles, Leger, Pierre-Louis, Rambaud, Jérôme, Thueux, Emilie, De Larrard, Alexandra, Berthelot, Véronique, Denot, Julien, Reymond, Marie, Amblard, Alain, Morin-Zorman, Sarah, Lengliné, Etienne, Pichereau, Claire, Mariotte, Eric, Emmanuel, Canet, Poujade, Julien, Trumpff, Guillaume, Janssen-Langenstein, Ralf, Harlay, Marie-Line, Zaid, Noorah, Ait-Ammar, Nawel, Bonnal, Christine, Merle, Jean-Claude, Botterel, Francoise, Levesque, Eric, Riad, Zakaria, Mezidi, Mehdi, Yonis, Hodane, Aublanc, Mylène, Perinel-Ragey, Sophie, Lissonde, Floriane, Louf-Durier, Aurore, Tapponnier, Romain, Louis, Bruno, Forel, Jean-Marie, Bisbal, Magali, Lehingue, Samuel, Rambaud, Romain, Adda, Mélanie, Hraiech, Sami, Marchi, Elisa, Roch, Antoine, Guerin, Vincent, Rozencwajg, Sacha, Schmidt, Matthieu, Hekimian, Guillaume, Bréchot, Nicolas, Trouillet, Jean Louis, Besset, Sébastien, Franchineau, Guillaume, Nieszkowska, Ania, Pascal, Leprince, Loiselle, Maud, Sarah, Chemam, Laurence, Dangers, Guillemette, Thomas, Jacquens, Alice, Kerever, Sebastien, Guidet, Bertrand, Aegerter, Philippe, Das, Vincent, Fartoukh, Muriel, Hayon, Jan, Desmard, Mathieu, Fulgencio, Jean-Pierre, Zuber, Benjamin, Soufi, A., Khaleq, K., Hamoudi, D., Garret, Charlotte, Peron, Matthieu, Coron, Emmanuel, Bretonnière, Cédric, Audureau, Etienne, Audrey, Winters, Christophe, Duvoux, Christian, Jacquelinet, Daniel, Azoulay, Cyrille, Feray, Aissaoui, Wissal, Rghioui, Kawtar, Haddad, Wafae, Barrou, Houcine, Carteaux-Taeib, Anna, Lupinacci, Renato, Manceau, Gilles, Jeune, Florence, Tresallet, Christophe, Habacha, Sahar, Fathallah, Ines, Zoubli, Aymen, Aloui, Rafaa, Kouraichi, Nadia, Jouet, Emilie, Badin, Julie, Fermier, Brice, Feller, Marc, Serie, Mathieu, Pillot, Jérôme, Marie, William, Gisbert-Mora, Chloé, Vinclair, Camille, Lesbordes, Pierre, Mathieu, Pascal, De Brabant, Fabienne, Muller, Emmanuel, Robaux, Marie-Aline, Giabicani, Mikhael, Marchalot, Antoine, Gelinotte, Stéphanie, Declercq, Pierre Louis, Eraldi, Jean-Pierre, Bougerol, François, Meunier-Beillard, Nicolas, Devilliers, Hervé, Rigaud, Jean-Philippe, Verrière, Camille, Ardisson, Fanny, Kentish-Barnes, Nancy, Jacq, Gwenaëlle, Chermak, Akli, Lautrette, Alexandre, Legrand, Matthieu, Soummer, Alexis, Thiery, Guillaume, Cottereau, Alice, Canet, Emmanuel, Caujolle, Marie, Allyn, Jérôme, Valance, Dorothée, Brulliard, Caroline, Martinet, Olivier, Jabot, Julien, Gallas, Thomas, Vandroux, David, Allou, Nicolas, Durand, Arthur, Nevière, Rémi, Delguste, Florian, Boulanger, Eric, Preau, Sebastien, Martin, Ruste, Cochet, Hélène, Ponthus, Jean Pierre, Amilien, Virginie, Tchir, Martial, Barsam, Elise, Ayoub, Mohsen, Georger, Jean Francois, Guillame, Izaute, Assaraf, Julie, Tripon, Simona, Mallet, Maxime, Barbara, Guilaume, Louis, Guillaume, Gaudry, Stéphane, Barbarot, Nicolas, Jamet, Angéline, Outin, Hervé, Gibot, Sébastien, Bollaert, Pierre-Edouard, Holleville, Mathilde, Legriel, Stéphane, Chateauneuf, Anne Laure, Cavelot, Sébastien, Moyer, Jean-Denis, Bedos, Jean Pierre, Merle, Philippe, Laine, Aurelie, Natalie, De Sa, Cornuault, Mathieu, Libot, Jérome, Asehnoune, Karim, Rozec, Bertrand, Dantal, Jacques, Videcoq, Michel, Degroote, Thècle, Jaillette, Emmanuelle, Zerimech, Farid, Malika, Balduyck, Llitjos, Jean-François, Amara, Marlène, Lacave, Guillaume, Pangon, Béatrice, Mavinga, José, Makunza, Joseph Nsiala, Mafuta, M. E., Yanga, Yves, Eric, Amisi, Ilunga, Jp, Kilembe, Ma, Alby-Laurent, Fanny, Toubiana, Julie, Mokline, Amel, Laajili, Achraf, Amri, Helmi, Rahmani, Imene, Mensi, Nidhal, Gharsallah, Lazheri, Tlaili, Sofiene, Gasri, Bahija, Hammouda, Rym, Messadi, Amen Allah, Allain, Pierre-Antoine, Gault, Nathallie, Paugam-Burtz, Catherine, Foucrier, Arnaud, Chatbri, Bassem, Bourbiaa, Yousra, Thabet, Lamia, Neuschwander, Arthur, Vincent, Looten, Beck, Jennifer, Vibol, Chhor, Amelie, Yavchitz, Resche-Rigon, Matthieu, Pirracchio, Jean MantzRomain, Bureau, Côme, Decavèle, Maxens, Campion, Sébastien, Ainsouya, Roukia, Niérat, Marie-Cécile, Prodanovic, Hélène, Raux, Mathieu, Similowski, Thomas, Dubé, Bruno-Pierre, Demiri, Suela, Dres, Martin, May, Faten, Quintard, Hervé, Kounis, Ilias, Saliba, Faouzi, André, Stephane, Boudon, Marc, Ichai, Philippe, Younes, Aline, Nakad, Lionel, Coilly, Audrey, Antonini, Teresa, Sobesky, Rodolphe, De Martin, Eleonora, Samuel, Didier, Hubert, Noemie, Nay, Mai-Anh, Auchabie, Johann, Giraudeau, Bruno, Jean, Reignier, Darmon, Michaël, Ruckly, Stephane, Garrouste-Orgeas, Maïté, Gratia, Elisabeth, Goldgran-Toledano, Dany, Jamali, Samir, Dumenil, Anne Sylvie, Schwebel, Carole, Brisard, Laurent, Bizouarn, Philippe, Lepoivre, Thierry, Nicolet, Johanna, Rigal, Jean Christophe, Roussel, Jean Christian, Cheurfa, Cherifa, Abily, Julien, Lescot, Thomas, Page, Isaline, Warnier, Stéphanie, Nys, Monique, Rousseau, Anne-Françoise, Damas, Pierre, Uhel, Fabrice, Lesouhaitier, Mathieu, Grégoire, Murielle, Gaudriot, Baptiste, Gacouin, Arnaud, Le Tulzo, Yves, Flecher, Erwan, Tarte, Karin, Tadié, Jean-Marc, Georges, Quentin, Soares, M., Jeon, Kyeongman, Oeyen, Sandra, Rhee, Chin Kook, Gruber, Pascale, Ostermann, Marlies, Hill, Quentin, Depuydt, Peter, Ferra, Christelle, Muller, Alice, Aurelie, Bourmaud, Niles, Christopher, Herbert, Fabien, Pied, Sylviane, Loridant, Séverine, François, Nadine, Bignon, Anne, Sendid, Boualem, Lemaitre, Caroline, Dupre, Celine, Zayene, Aymen, Portier, Lucie, De Freitas Caires, Nathalie, Lassalle, Philippe, Le Neindre, Aymeric, Selot, Pascal, Ferreiro, Daniel, Bonarek, Maria, Henriot, Stépahen, Rodriguez, Julie, Taddei, Mara, Di Bari, Mauro, Hickmann, Cheryl, Castanares-Zapatero, Diego, Deldicque, Louise, Van Den Bergh, Peter, Caty, Gilles, Roeseler, Jean, Francaux, Marc, Laterre, Pierre-François, Dupuis, Bastien, Machayeckhi, Sharam, Sarfati, Celine, Moore, Alex, Mendialdua, Paula, Rodet, Emilie, Pilorge, Catherine, Stephan, Francois, Rezaiguia-Delclaux, Saida, Dugernier, Jonathan, Hesse, Michel, Jumetz, Thibaud, Bialais, Emilie, Depoortere, Virginie, Michotte, Jean Bernard, Wittebole, Xavier, Jamar, François, REA‑RAISIN Studygroup, OUTCOMEREA study group, Sudden Death Expertise Center, for the HYPER2S Investigators and REVA research network, Clinical Research in Intensive Care and Sepsis (CRICS network), Cubrea network, and Brain Liver Pitié-Salpêtrière Study Group (BLIPS)

Published
2017
Full Text
View/download PDF

42. Association of Early Norepinephrine Administration With 24-Hour Mortality Among Patients With Blunt Trauma and Hemorrhagic Shock

Author

Gauss, Tobias, Richards, Justin, Tortù, Costanza, Ageron, François-Xavier, Hamada, Sophie, Josse, Julie, Husson, François, Harrois, Anatole, Scalea, Thomas, Vivant, Valentin, Meaudre, Eric, Morrison, Jonathan, Galvagno, Samue, Bouzat, Pierre, Albasini, François, Briot, Olivier, Chaboud, Laurent, Chateigner Coelsch, Sophie, Chaumat, Alexandre, Comlar, Thomas, Debas, Olivier, Debaty, Guillaume, Dupré-Nalet, Emmanuelle, Gay, Samuel, Ginestie, Edouard, Girard, Edouard, Grèze, Jules, Haesevoets, Marc, Hallain, Marie, Haller, Etienne, Hoareau, Christophe, Lanaspre, Bernard, Lespinasse, Safia, Levrat, Albrice, Mermillod-Blondin, Romain, Nicoud, Philippe, Rancurel, Elisabeth, Thouret, Jean-Marc, Vallenet, Claire, Vallot, Cécile, Zerr, Bénédicte, Abback, Paér-Sélim, Audibert, Gérard, Boutonnet, Mathieu, Clavier, Thomas, Cook, Fabrice, Eljamri, Mohamed, Floch, Thierry, Gaertner, Elisabeth, Garrigue, Delphine, Geeraerts, Thomas, Gette, Sebastien, Godier, Anne, Gosset, Pierre, Hanouz, Jean-Luc, Moyer, Jean-Denis, Langeron, Olivier, Leone, Marc, Pottecher, Julien, Portaz, Jonathan, Raux, Mathieu, Scotto, Marion, Willig, Mathieu, Hardy, Alexia, French Trauma Research Initiative, Albasini, F., Briot, O., Chaboud, L., Chateigner Coelsch, S., Chaumat, A., Comlar, T., Debas, O., Debaty, G., Dupré-Nalet, E., Gay, S., Ginestie, E., Girard, E., Grèze, J., Haesevoets, M., Hallain, M., Haller, E., Hoareau, C., Lanaspre, B., Lespinasse, S., Levrat, A., Mermillod-Blondin, R., Nicoud, P., Rancurel, E., Thouret, J.M., Vallenet, C., Vallot, C., Zerr, B., Abback, P.S., Audibert, G., Boutonnet, M., Clavier, T., Cook, F., Eljamri, M., Floch, T., Gaertner, E., Garrigue, D., Geeraerts, T., Gette, S., Godier, A., Gosset, P., Hanouz, J.L., Moyer, J.D., Langeron, O., Leone, M., Pottecher, J., Portaz, J., Raux, M., Scotto, M., Willig, M., Hardy, A., Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital d'Annecy, Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Inria-SIC [Sophia Antipolis], Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Institut Desbrest de santé publique (IDESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Médecine de précision par intégration de données et inférence causale (PREMEDICAL), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Institut Desbrest de santé publique (IDESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Institut de Recherche Mathématique de Rennes (IRMAR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École normale supérieure - Rennes (ENS Rennes)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut Agro Rennes Angers, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Hôpital Bicêtre, Université Paris-Saclay, Hôpital d'Instruction des Armées Sainte Anne, Service de Santé des Armées, École du Val de Grâce (EVDG), CHU Grenoble, [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Hopital Saint-Jean-de-Maurienne, Laboratoire Charles Coulomb (L2C), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), and ANR-11-LABX-0020,LEBESGUE,Centre de Mathématiques Henri Lebesgue : fondements, interactions, applications et Formation(2011)

Subjects
Male, Norepinephrine, [MATH.MATH-ST]Mathematics [math]/Statistics [math.ST], Humans, Hemorrhage, General Medicine, Middle Aged, Shock, Hemorrhagic, Wounds, Nonpenetrating, Hemorrhage/drug therapy, Norepinephrine/therapeutic use, Retrospective Studies, Shock, Hemorrhagic/drug therapy, Wounds, Nonpenetrating/complications, Wounds, Nonpenetrating/drug therapy
Abstract

ImportanceHemorrhagic shock is a common cause of preventable death after injury. Vasopressor administration for patients with blunt trauma and hemorrhagic shock is often discouraged.ObjectiveTo evaluate the association of early norepinephrine administration with 24-hour mortality among patients with blunt trauma and hemorrhagic shock.Design, Setting, and ParticipantsThis retrospective, multicenter, observational cohort study used data from 3 registries in the US and France on all consecutive patients with blunt trauma from January 1, 2013, to December 31, 2018. Patients were alive on admission with hemorrhagic shock, defined by prehospital or admission systolic blood pressure less than 100 mm Hg and evidence of hemorrhage (ie, prehospital or resuscitation room transfusion of packed red blood cells, receipt of emergency treatment for hemorrhage control, transfusion of >10 units of packed red blood cells in the first 24 hours, or death from hemorrhage). Blunt trauma was defined as any exposure to nonpenetrating kinetic energy, collision, or deceleration. Statistical analysis was performed from January 15, 2021, to February 22, 2022.ExposureContinuous administration of norepinephrine in the prehospital environment or resuscitation room prior to hemorrhage control, according to European guidelines.Main Outcomes and MeasuresThe primary outcome was 24-hour mortality, and the secondary outcome was in-hospital mortality. The average treatment effect (ATE) of early norepinephrine administration on 24-hour mortality was estimated according to the Rubin causal model. Inverse propensity score weighting and the doubly robust approach with 5 distinct analytical strategies were used to determine the ATE.ResultsA total of 52 568 patients were screened for inclusion, and 2164 patients (1508 men [70%]; mean [SD] age, 46 [19] years; median Injury Severity Score, 29 [IQR, 17-36]) presented with acute hemorrhage and were included. A total of 1497 patients (69.1%) required emergency hemorrhage control, 128 (5.9%) received a prehospital transfusion of packed red blood cells, and 543 (25.0%) received a massive transfusion. Norepinephrine was administered to 1498 patients (69.2%). The 24-hour mortality rate was 17.8% (385 of 2164), and the in-hospital mortality rate was 35.6% (770 of 2164). None of the 5 analytical strategies suggested any statistically significant association between norepinephrine administration and 24-hour mortality, with ATEs ranging from –4.6 (95% CI, –11.9 to 2.7) to 2.1 (95% CI, –2.1 to 6.3), or between norepinephrine administration and in-hospital mortality, with ATEs ranging from –1.3 (95% CI, –9.5 to 6.9) to 5.3 (95% CI, –2.1 to 12.8).Conclusions and RelevanceThe findings of this study suggest that early norepinephrine infusion was not associated with 24-hour or in-hospital mortality among patients with blunt trauma and hemorrhagic shock. Randomized clinical trials that study the effect of early norepinephrine administration among patients with trauma and hypotension are warranted to further assess whether norepinephrine is safe for patients with hemorrhagic shock.

Published
2022

44. Prehospital Lyophilized Plasma Transfusion for Trauma-Induced Coagulopathy in Patients at Risk for Hemorrhagic Shock

Author

Jost, Daniel, Lemoine, Sabine, Lemoine, Frédéric, Derkenne, Clément, Beaume, Sébastien, Lanoë, Vincent, Maurin, Olga, Louis-Delaurière, Emilie, Delacote, Maëlle, Dang-Minh, Pascal, Franchin-Frattini, Marilyn, Bihannic, René, Savary, Dominique, Levrat, Albrice, Baudouin, Clémence, Trichereau, Julie, Salomé, Marina, Frattini, Benoit, Ha, Vivien Hong Tuan, Jouffroy, Romain, Seguineau, Edouard, Titreville, Rudy, Roquet, Florian, Stibbe, Olivier, Vivien, Benoit, Verret, Catherine, Bignand, Michel, Travers, Stéphane, Martinaud, Christophe, Arock, Michel, Raux, Mathieu, Prunet, Bertrand, Ausset, Sylvain, Sailliol, Anne, Tourtier, Jean-Pierre, Albinni, Souha, Attias, Arié, Benchetritt, Deborah, Benichou, Laura, Boizat, Stéphane, Boutinaud, Philippe, Calinet, Alexandra, Camoin-Jau, Laurence, Cerro, Valérie, Cesareo, Eric, Chahir, Noureddine, Chassery, Carine, Chollet, Charlotte, Choubard, Anouk, Clavere, Gaëlle, Clavier, Benoit, Courtade, Henri, Creppy, Séverine, David, Jean-Stéphane, de Raucourt, Emmanuelle, Debord, Sophie, Delort, Josée, Deruaz-Cunsolo, Christine, Dettori, Isabelle, Dhers, Marion, Dias, Patricia, Diaz, Maxime, Dieuset, Sophie, Dubien, Pierre-Yves, Duchateau, François-Xavier, Duranteau, Jacques, Fiot, Charlotte, Flocard, Bernard, Foissaud, Vincent, Fournier, Marc, Francois, Anne, Gaget, Gilles, Garnier, Benjamin, Gaste, Jean-Louis, Grimault, Olivier, Gueugniaud, Pierre-Yves, Idir, Zakia, Burnichon, Jerome, Journois, Didier, Blanc-Jouvan, Florence, Kerbaul, Francois, Klein, Isabelle, Lafitte, Blandine, Langeron, Olivier, Lassale, Bernard, Lebouc, Marie, Lecarpentier, Eric, Lejeune, Stephanie, Lemaire, Mickaël, Leniger, Catherine, Leone, Marc, Leostic, Claudie, Lutomski, Chantal, Sailliol, Marianne, Martin, Claude-Denis, Matheron, Catherine, Mathieu, Jacques, Mendes, Anne-Christine, Mermillod-Blondin, Romain, Neuschwander, Arthur, Oueidat, Nathalie, Ould-Ahmed, Mehdi, Ozier, Yves, Paugam, Catherine, Peduzzi, Franck, Petermann, Alexandre, Peytel, Eric, Picou-Leblanc, Muriel, Pinero, David, Plaisance, Patrick, Raba, Michel, Ricard, Damien, Romanacce, Isabelle, Rossignol, Thomas, Rougelin-Clapasson, Christine, Saint-Paul, Amelie, Idri, Salim, Scotto, Christine, Senent, Laurence, Smadja, David, Tazarourte, Karim, Topin, Francois, Trichet, Catherine, Vocel, Alexia, Laboratoire de biologie et modélisation de la cellule (LBMC UMR 5239), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Brigade de sapeurs pompiers de Paris (BSPP), CEDRIC. Réseaux et Objets Connectés (CEDRIC - ROC), Centre d'études et de recherche en informatique et communications (CEDRIC), Ecole Nationale Supérieure d'Informatique pour l'Industrie et l'Entreprise (ENSIIE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Ecole Nationale Supérieure d'Informatique pour l'Industrie et l'Entreprise (ENSIIE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), École des Hautes Études en Santé Publique [EHESP] (EHESP), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Centre Hospitalier Annecy-Genevois [Saint-Julien-en-Genevois], Hôpital Foch [Suresnes], CIC - Mère Enfant Necker Cochin Paris Centre (CIC 1419), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Service de biostatistique et information médicale de l’hôpital Saint Louis (Equipe ECSTRA) (SBIM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut national du cancer [Boulogne] (INCA)-Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), GHU AP-HP Centre Université de Paris, CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de Recherche Biomédicale des Armée [Brétigny/Orge] (IRBA), Centre de Transfusion Sanguine des Armées (CTSA), Service de Santé des Armées, Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Neurophysiologie Respiratoire Expérimentale et Clinique (UMRS 1158), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), AP-HP - Hôpital Antoine Béclère [Clamart], CHU Henri Mondor [Créteil], Université de Bretagne Occidentale - UFR Médecine et Sciences de la Santé (UBO UFR MSS), and Université de Brest (UBO)

Subjects
[SDV]Life Sciences [q-bio]
Abstract

International audience; IMPORTANCE Blood transfusion is a mainstay of therapy for trauma-induced coagulopathy, but the optimal modalities for plasma transfusion in the prehospital setting remain to be defined. OBJECTIVE To determine whether lyophilized plasma transfusion can reduce the incidence of trauma-induced coagulopathy compared with standard care consisting of normal saline infusion. DESIGN, SETTING, AND PARTICIPANTS This randomized clinical trial was performed at multiple centers in France involving prehospital medical teams. Participants included 150 adults with trauma who were at risk for hemorrhagic shock and associated coagulopathy between April 1, 2016, and

Published
2022

45. Omicron Variant in the Critical Care Units of the Paris Metropolitan Area: The Reality Research Group

Author

Vieillard-Baron, Antoine, primary, Flicoteaux, Rémi, additional, Salmona, Maud, additional, Chariot, Appoline, additional, De Maupeou D’Ableiges, Bertrand, additional, Darmon, Michael, additional, Batteux, Frédéric, additional, Annane, Djillali, additional, Ayed, Soufia, additional, Azoulay, Elie, additional, Bellaiche, Raphael, additional, Beloucif, Sadek, additional, Berti, Enora, additional, Bertier, Astrid, additional, Besset, Sébastien, additional, Bret, Marlène, additional, Cariou, Alain, additional, Carpentier, Christophe, additional, Chaouch, Oussama, additional, Charron, Cyril, additional, Charpentier, Julien, additional, Cheurfa, Cherifa, additional, Cholley, Bernard, additional, Chousterman, Benjamin, additional, Clerc, Sébastien, additional, Cohen, Yves, additional, Combes, Alain, additional, Constantin, Jean-Michel, additional, Damoisel, Charles, additional, Degos, Vincent, additional, Demeret, Sophie, additional, De Montmollin, Etienne, additional, Demoule, Alexandre, additional, Depret, Francois, additional, Diehl, Jean-Luc, additional, Djibré, Michel, additional, Do, Chung-Hi, additional, Dudoignon, Emmanuel, additional, Duranteau, Jacques, additional, Fartoukh, Muriel, additional, Fieux, Fabienne, additional, Gayat, Etienne, additional, Gennequin, Mael, additional, Guidet, Bertrand, additional, Gutton, Christophe, additional, Hamada, Sophie, additional, Heming, Nicholas, additional, Jouffroy, Romain, additional, Keita-Meyer, Hawa, additional, Langeron, Olivier, additional, Lortat-Jacob, Brice, additional, Marey, Jonathan, additional, Mebazaa, Alexandre, additional, Megarbane, Bruno, additional, Mekontso-Dessap, Armand, additional, Mira, Jean-Paul, additional, Molle, Julie, additional, Mongardon, Nicolas, additional, Montravers, Philippe, additional, Morelot-Panzini, Capucine, additional, Nemlaghi, Safaa, additional, Nguyen, Bao-long, additional, Parrot, Antoine, additional, Pasqualotto, Romain, additional, Peron, Nicolas, additional, Picard, Lucile, additional, de Chambrun, Marc Pineton, additional, Planquette, Benjamin, additional, Plaud, Benoit, additional, Pons, Stéphanie, additional, Quesnel, Christophe, additional, Raphalen, Jean-Herlé, additional, Razazi, Keyvan, additional, Ricard, Jean-Damien, additional, Roche, Anne, additional, Rohaut, Benjamin, additional, Roux, Damien, additional, Savale, Laurent, additional, Sobotka, Jennifer, additional, Teboul, Jean-Louis, additional, Timsit, Jean-François, additional, Voiriot, Guillaume, additional, Weiss, Emmanuel, additional, Wildenberg, Lucille, additional, Zogheib, Elie, additional, and Riou, Bruno, additional

Published
2022
Full Text
View/download PDF

48. Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions

Author

Gouel-Chéron, A, de Chaisemartin, L, Jönsson, F, Nicaise-Roland, P, Granger, V, Sabahov, A, Guinnepain, M-T, Chollet-Martin, S, Bruhns, P, Neukirch, C, Longrois, D, Montravers, Philippe, Gillis, Caitlin M, Mancardi, David A, Aubier, Michel, Sauvan, Caroline, Fischler, Marc, Bresson, Julie, Paugam-Burtz, Catherine, Necib, Skander, Mebazaa, Alexandre, Le Dorze, Matthieu, Jacob, Laurent, Chahine, Carole, Keita-Meyer, Hawa, Faitot, Valentina, Langeron, Olivier, Roche, Sabrine, Cholley, Bernard, and Mantz, Jean

Published
2017
Full Text
View/download PDF

50. Lack of vaccination in ventilated patients for SARS-CoV-2 in France

Author

Joannes-Boyau, Olivier, primary, Dahyot-Fizelier, Claire, additional, Albaladejo, Pierre, additional, Bouaziz, Hervé, additional, Cittanova, Marie-Laure, additional, Constantin, Jean-Michel, additional, Delaunay, Laurent, additional, Leone, Marc, additional, Nouette-Gaulain, Karine, additional, Allaouchiche, Bernard, additional, Amathieu, Roland, additional, Atchade, Enora, additional, Besnier, Emmanuel, additional, Bouhemad, Belaid, additional, Chousterman, Benjamin, additional, Collange, Olivier, additional, Degos, Vincent, additional, Langeron, Olivier, additional, Launey, Yoann, additional, Mayeur, Nicolas, additional, Miatello, Jordi, additional, Mongardon, Nicolas, additional, Morel, Jérôme, additional, Trouiller, Pierre, additional, Bounes, Fanny Vardon, additional, and Fazilleau, Claire, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results