Search

Your search keyword '"Langermans, Jan AM"' showing total 8 results
Start Over Author "Langermans, Jan AM"
8 results on '"Langermans, Jan AM"'

1. Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs

Author

Flahou, Bram, Rossi, Mirko, Bakker, Jaco, Langermans, Jan AM, Heuvelman, Edwin, Solnick, Jay V, Martin, Miriam E, O’Rourke, Jani, Ngoan, Le Duc, Hoa, Nguyen Xuan, Nakamura, Masahiko, Øverby, Anders, Matsui, Hidenori, Ota, Hiroyoshi, Matsumoto, Takehisa, Foss, Dennis L, Kopta, Laurice A, Omotosho, Oladipo, Franciosini, Maria Pia, Casagrande Proietti, Patrizia, Guo, Aizhen, Liu, Han, Borilova, Gabriela, Bracarense, Ana Paula, Lindén, Sara K, De Bruyckere, Sofie, Zhang, Guangzhi, De Witte, Chloë, Smet, Annemieke, Pasmans, Frank, Ducatelle, Richard, Corander, Jukka, and Haesebrouck, Freddy

Subjects
Biological Sciences, Environmental Sciences, Infectious Diseases, Emerging Infectious Diseases, Digestive Diseases, Infection, Animals, Animals, Domestic, Helicobacter Infections, Helicobacter heilmannii, Humans, Macaca fascicularis, Macaca mulatta, Phylogeny, Stomach, Swine, Swine Diseases, Technology, Microbiology, Biological sciences, Environmental sciences
Abstract

Helicobacter suis is the second most prevalent Helicobacter species in the stomach of humans suffering from gastric disease. This bacterium mainly inhabits the stomach of domesticated pigs, in which it causes gastric disease, but it appears to be absent in wild boars. Interestingly, it also colonizes the stomach of asymptomatic rhesus and cynomolgus monkeys. The origin of modern human-, pig- or non-human primate-associated H. suis strains in these respective host populations was hitherto unknown. Here we show that H. suis in pigs possibly originates from non-human primates. Our data suggest that a host jump from macaques to pigs happened between 100 000 and 15 000 years ago and that pig domestication has had a significant impact on the spread of H. suis in the pig population, from where this pathogen occasionally infects humans. Thus, in contrast to our expectations, H. suis appears to have evolved in its main host in a completely different way than its close relative Helicobacter pylori in humans.

Published
2018

3. Revised recommendations for health monitoring of non-human primate colonies (2018): FELASA Working Group Report

Author

Balansard, Ivan, Cleverley, Lorna, Cutler, Keith L, Spångberg, Mats G, Thibault-Duprey, Kevin, Langermans, Jan Am, LAS/3’R Centre ULS, and LAS/3’R Centre ULS

Subjects
040301 veterinary sciences, Health Status, Anthroponotic disease, animal diseases, husbandry, Guidelines as Topic, Certification, laboratory animal welfare, Animal Welfare, 0403 veterinary science, 03 medical and health sciences, Working Party Report, Animals, Laboratory, Environmental health, biology.animal, medicine, Animals, Primate, care, Animal Husbandry, Saimiri, 030304 developmental biology, 0303 health sciences, Non human primate, General Veterinary, biology, business.industry, Saimiri sciureus, Marmoset, Callithrix, 04 agricultural and veterinary sciences, medicine.disease, biology.organism_classification, Macaca mulatta, Macaca fascicularis, Rhesus macaque, Animal Science and Zoology, quality assurance/control, business
Abstract

The genetic and biological similarity between non-human primates and humans has ensured the continued use of primates in biomedical research where other species cannot be used. Health-monitoring programmes for non-human primates provide an approach to monitor and control both endemic and incoming agents that may cause zoonotic and anthroponotic disease or interfere with research outcomes. In 1999 FELASA recommendations were published which aimed to provide a harmonized approach to health monitoring programmes for non-human primates. Scientific and technological progress, understanding of non-human primates and evolving microbiology has necessitated a review and replacement of the current recommendations. These new recommendations are aimed at users and breeders of the commonly used non-human primates; Macaca mulatta (Rhesus macaque) and Macaca fascicularis (Cynomolgus macaque). In addition, other species including Callithrix jacchus (Common marmoset) Saimiri sciureus (Squirrel monkey) and others are included. The important and challenging aspects of non-human primate health-monitoring programmes are discussed, including management protocols to maintain and improve health status, health screening strategies and procedures, health reporting and certification. In addition, information is provided on specific micro-organisms and the recommended frequency of testing.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results