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Your search keyword '"Lane, Michael J."' showing total 118 results
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118 results on '"Lane, Michael J."'

1. The Australasian Registry for Severe Cutaneous Adverse Reactions (AUS-SCAR) – Providing a roadmap for closing the diagnostic, patient, and healthcare gaps for a group of rare drug eruptions

Author

James, Fiona, Goh, Michelle S., Vogrin, Sara, Ng, Irvin, Douglas, Abby P., Holmes, Natasha E., Chua, Kyra YL., De Luca, Joseph, Sharma, Pooja, Zubrinich, Celia, Aung, Ar K., Gin, Douglas, Lambros, Belinda, Baker, Chris, Foley, Peter, Chong, Alvin H., Thien, Francis, Fok, Jie S., Su, John, Scardamaglia, Laura, Awad, Andrew, Tong, Steven, Johnson, Douglas, Godsell, Jack, Arasu, Alexis, Barnes, Sara, Ojaimi, Samar, Mar, Adrian, Yun, James, Ange, Nikhita, Tong, Winnie W.Y., Carr, Andrew, Loprete, Jacqueline, Katelaris, Constance H., Slape, Dana, Keat, Karuna, West, Timothy A., Lee, Monique, Smith, William, Hissaria, Pravin, Sidhu, Shireen, Janson, Sonja, Venkatesan, Sudharsan, Davies, Jane, Lane, Michael J., Redmond, Andrew M., Robertson, Ivan, Legg, Amy, Fernando, Suran, Boyle, Therese, Li, Jamma, Phillips, Elizabeth J., Cleland, Heather, Kern, Johannes S., and Trubiano, Jason A.

Published
2024
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13. Sequence context and DNA reactivity

Author

Benight, Albert S., primary, Gallo, Frank J., additional, Paner, Teodoro M., additional, Bishop, Karl D., additional, Faldasz, Brian D., additional, and Lane, Michael J., additional

Published
1996
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35. Thermodynamic, spectroscopic, and equilibrium binding studies of DNA sequence context effects in six 22-base pair deoxyoligonucleotides

Author

Riccelli, Peter V., Vallone, Peter M., Kashin, Irina, Faldasz, Brian D., Lane, Michael J., and Benight, Albert S.

Subjects
DNA, Nucleotide sequence -- Research, Protein binding -- Research, Biological sciences, Chemistry
Abstract

Research was conducted to examine the effects of various end sequences on stability, circular dichroism spectra (CD) and enzyme binding properties for six 22-base pair, non-self-complementary duplex DNA oligomers. Differential scanning calorimetry was used to monitor temperature-induced melting transitions, which, together with ultraviolet absorbance, were calculated for the six duplexes in buffered 115 mM Na+ solutions. Melting stability was found to be a direct predictor of how variations in flanking sequence affect enzyme binding.

Published
1999

46. Alternative Strategies for Human Genomic Mapping

Author

Lane, Michael J, primary, Smardon, Anne M, primary, Hanlon, Douglas J, primary, Hahn, Peter J, primary, Carroll, William T, primary, Waterbury, P Greg, primary, Faldasz, Brian D, primary, Huckaby, Clark S, primary, and Mante, Seth, primary

Published
1991
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48. Unenhanced helical CT scanning of the abdomen and pelvis changes disposition of patients presenting to the emergency department with possible acute appendicitis1 <FN ID="FN1"><NO>1</NO>Original Contributions is coordinated by John A. Marx, MD, of Carolinas Medical Center, Charlotte, North Carolina</FN>

Author

Christopher, Frank L., Lane, Michael J., Ward, John A., and Morgan, J. Alan

Subjects
*APPENDICITIS diagnosis, *TOMOGRAPHY
Abstract

This study sought to determine if obtaining an unenhanced abdominopelvic computed tomography (UHCT) scan alters the disposition of patients presenting to the Emergency Department (ED) with signs and symptoms of acute appendicitis. A convenience sample of 101 patients presenting with a clinical picture suggestive of appendicitis were prospectively enrolled. Emergency physicians (EPs) and general surgeons independently recorded their anticipated disposition of each patient as: discharge, admit for observation, or admit for appendectomy. A UHCT scan was then obtained and the patient’s ultimate disposition recorded. EPs altered their dispositions after UHCT scanning in 35 patients (34.7%, 95% CI 25.4% to 44.0%), and general surgeons altered their dispositions in 27 patients (26.7%, 95% CI 18.1% to 35.3%). More patients underwent operative intervention than were originally selected by EPs [14 additional patients, (13.9%, 95% CI 7.1% to 20.6%)] or by surgeons [20 additional patients, (19.8%, 95% CI 12.0% to 27.6%)]. CT scan revealed alternative diagnoses in 20 patients (19.8%). UHCT scanning significantly alters patient disposition, and significantly increases the number of operative interventions performed in patients with suspected appendicitis. UHCT scanning may also identify alternate pathology that clinically mimics appendicitis. [Copyright &y& Elsevier]

Published
2002
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