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294 results on '"Landry T"'

1. In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

Author

Albert A. Gnondjui, Offianan A. Toure, Berenger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’Guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo, and Ronan Jambou

Subjects
Sickle cell anemia, Artemisinin combination therapy, Plasmodium falciparum, Anti-malarial drugs, Treatment resistance, In vitro drug monitoring, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background Decreased efficacy of artemisinin-based combination therapy (ACT) for Plasmodium falciparum malaria has been previously reported in patients with sickle cell disease (SCD). The main purpose of this study was to investigate the in vitro susceptibility of isolates to dihydro-artemisinin (DHA) to provide a hypothesis to explain this treatment failure. Methods Isolates were collected from patients attending health centres in Abidjan with uncomplicated P . falciparum malaria. The haemoglobin type has been identified and in vitro drug sensitivity tests were conducted with the ring stage assay and maturation inhibition assay. Results 134 isolates were obtained. Parasitaemia and haemoglobin levels at inclusion were lower in patients with haemoglobin HbSS and HbSC than in patients with normal HbAA. After ex vivo RSA and drug inhibition assays, the lowest rate of parasitic growth was found with isolates from HbAS red cells. Conversely, a significantly higher survival rate of parasites ranging from 15 to 34% were observed in isolates from HbSS. Isolates with in vitro reduced DHA sensitivity correlate with lower RBC count and haematocrit and higher parasitaemia at inclusion compared to those with isolates with normal DHA sensitivity. However, this decrease of in vitro sensitivity to DHA was not associated with Kelch 13-Propeller gene polymorphism. Conclusion This study highlights an in vitro decreased sensitivity to DHA, for isolates collected from HbSS patients, not related to the Pfkelch13 gene mutations. These results are in line with recent studies pointing out the role of the redox context in the efficacy of the drug. Indeed, SCD red cells harbour a highly different ionic and redox context in comparison with normal red cells. This study offers new insights into the understanding of artemisinin selective pressure on the malaria parasite in the context of haemoglobinopathies in Africa.

Published
2024
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3. Coverage and efficacy of intermittent preventive treatment with sulphadoxine pyrimethamine against malaria in pregnancy in Côte d’Ivoire five years after its implementation

Author

Offianan A Toure, Penali L Kone, M’Lanhoro AA Coulibaly, Berenger AA Ako, Eric A Gbessi, Baba Coulibaly, Landry T N’ Guessan, David Koffi, Sylvain Beourou, Adama Soumahoro, Issiaka Bassinka, Messoun Nogbou, Tidjane Swa, Bernadin Gba, Beugre Esmel, and Ernestine M Bokossa

Subjects
Coverage, IPTp-sp, Malaria, Efficacy, Côte d’Ivoire, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background The World Health Organization (WHO) recommends for sub-Saharan Africa a package of prompt and effective case-management combined with the delivery of insecticide-treated nets (ITN) and intermittent preventive treatment during pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) through the national antenatal care (ANC) programs. Implemented in Côte d’Ivoire around 2005, few Data on IPTp coverage and efficacy in the country are available. Methods A multicentre, cross-sectional survey was conducted in Côte d’Ivoire from September 2009 to May 2010 at six urban and rural antenatal clinics. IPTp-sp coverage, Socio-economic and obstetrical data of mothers and neonate birth weights were documented. Peripheral blood as well as placental and cord blood were used to prepare thick and thin blood films. In addition, pieces of placental tissues were used to prepare impression smears and maternal haemoglobin concentration was measured. Regression logistics were used to study factors associated with placental malaria and LBW (

Published
2014
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5. In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

Author

Gnondjui, Albert A., primary, Toure, Offianan A., additional, Ako, Beranger A., additional, Koui, Tossea S., additional, Assohoun, Stanislas E., additional, Gbessi, Eric A., additional, N’guessan, Landry T., additional, Tuo, Karim, additional, Beourou, Sylvain, additional, Assi, Serge-Brice, additional, Yapo, Francis A., additional, Sanogo, Ibrahima, additional, and Jambou, Ronan, additional

Published
2023
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6. In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

Author

Albert A. Gnondjui, Offianan A. Toure, Beranger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo, and Ronan Jambou

Abstract

Background Decreased efficacy of artemisinin-based combination therapies (ACTs) during Plasmodium falciparum malaria attack has been previously reported in patients with sickle cell disease (SCD). The main purpose of this study was to investigate the in vitro susceptibility of isolates to DHA to find out hypothesis backing up the reason of this treatment failure.Method Isolates from patients attending health centers in Abidjan with uncomplicated P.falciparum malaria were collected. Hemoglobin type has been identified and in vitro drug sensitivity tests were conducted with the Ring Stage Assay and maturation inhibition assay.Results 134 isolates were selected. Parasitemia and hemoglobin level at inclusion were lower in patients with hemoglobin HbSS and HbSC than in patients with normal HbAA.

Published
2023

8. Poster Summaries

Author

Gucciardo, Sébastien, Wisniewski, Jean-Pierre, Mak, Lora, Durrant, Marcus, Rathbun, Elizabeth, Brewin, Nick, Suzuki, Akihiro, Akune, Mitsumi, Imagama, Yoshihiro, Osuki, Ken-ichi, Aoki, Toshio, Uchiumi, Toshiki, Abe, Mikiko, Chou, Minxia, Zhou, Junchu, Xie, Bo, Miao, Lihong, Zhou, Kui, Xie, Fuli, Cheng, Xian-Guo, Tajima, Shigeyuki, Kouchi, Hiroshi, Wang, Yanzhang, Yu, Guan-Qiao, Zhu, Jia-Bi, He, Zhishui, Xie, Rong, Terakado, Junko, Yoneyama, Tadakatsu, Fujihara, Shinsuke, Ooki, Y., Banba, M., Yano, K., Maruya, J., Sato, S., Tabata, S., Saeki, K., Hayashi, M., Kawaguchi, M., Izui, K., Hata, S., Deguchi, Y., Checchetka, S.A., Bamba, M., Maeda, D., Ashida, K., Iguchi, K., Nomura, Mika, Thu, Mai Ha, Yokoyama, Tadashi, Hakoyama, Tsuneo, Arima, Yasuhiro, Shimoda, Y., Higashi, Shiro, Yukihiro, Maru, Hiroki, Miwa, Toshihiro, Aono, Hiroshi, Oyaizu, Wei, Hui, Layzell, David B., Du, Bing Hai, Wang, Lei, Qi, Su Wei, Jiang, Ju Quan, Yang, Su Sheng, Cheng, J., Sibley, C. D., Landry, T., Chain, P. S. G., Lehman, S., Golding, G. B., Yuan, Ze-Chun, Morton, Richard A., Zaheer, Rahat, Rybak, Adrian, Finan, Turlough M., Guillén-Navarro, Karina, Araíza, Gisela, Dunn, Michael F., Nakatsukasa, Hiroki, Wen, Jin, Nan, Bei-Yan, O’Gara, Fergal, Yue, Wen, Wen, Bi-Qing, Wang, Yi-Ping, Yao, Shi-Yi, Luo, Li, Har, Katherine J., Becker, Anke, Cheng, Hai-Ping, Sasakura, Fuyuko, Takenouchi, Katsumi, Wang, Yi-Ping, editor, Lin, Min, editor, Tian, Zhe-Xian, editor, Elmerich, Claudine, editor, and Newton, William E., editor

Published
2005
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9. Decreased in vitro dihydroartemisinin sensitivity in malaria parasites infecting sickle cell disease patients

Author

Albert A. Gnondjui, Offianan A. Toure, Beranger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo, and Ronan Jambou

Abstract

BackgroundPartial ACTs treatment failure in Plasmodium falciparum malaria has been previously reported in sickle cell patients. The main purpose of this study was to investigate the in vitro susceptibility of clinical isolates to DHA to find out hypothesis backing up the reason of this poor therapeutic response.ResultsA total of 134 clinical isolates from patients attending health centers in Abidjan with uncomplicated Plasmodium falciparum malaria were selected. Hemoglobin HbAS, HbSS, HbAC, HbSC and HbAA were identified. Parasitemia and hemoglobin level at inclusion were lower in sickle cell patients with major forms than in patients with normal phenotype. A significant number of parasites with survival rates ranging from 14.68 to 33.75% were observed in clinical isolates from the SS phenotype. At inclusion, these resistant clinical isolates showed lower parasite densities, and patients had lower red blood cell count and hematocrit levels compared to those with susceptible clinical isolates. A low rate of parasitic growth has more often occurred with AS sickle cell phenotype. However, the decrease in in vitro sensitivity to DHA was not associated with Kelch 13-Propeller gene polymorphism.ConclusionThis study highlights an in vitro decreased sensitivity to DHA, for clinical isolates collected from sickle cell SS patients living in Abidjan (Côte d’Ivoire), which is not related to the Pfkelch13 gene mutations. These clinical isolates may represent a health threat for sickle cell disease patients especially during crisis. Moreover, these results could suggest additional mechanisms of artemisinin resistance that need to be explored.

Published
2022

10. Age Changes in the Missing-Letter Effect Revisited

Author

Saint-Aubin, J., Klein, R.M, and Landry, T.

Abstract

When participants search for a target letter while reading, they make more omissions if the target letter is embedded in frequent function words than in less frequent content words. Reflecting developmental changes in component language and literacy skills, the size of this effect increases with age. With adults, the missing-letter effect is due to both word function and word frequency. With children, it is unclear whether the growing size of the missing-letter effect across development is due to a larger effect of word function, word frequency, or both because previous studies with children seeking to isolate the influence of word frequency and word function suffer from important methodological limitations. With these methodological limitations eliminated (Experiments 1 and 2), performance in a letter detection task was assessed for children in Grades 1, 2, 3, 4, and 7 as well as for undergraduate students. The results revealed that the influence of word function increases with age, whereas the effect of frequency is fairly stable across ages. Furthermore, normative predictability data collected in Experiment 3 revealed that third graders and undergraduate students were equally good at predicting function slots in a sentence.

Published
2005
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12. Decreased in vitro dihydroartemisinin sensitivity in malaria parasites infecting sickle cell disease patients

Author

Gnondjui, Albert A., primary, Toure, Offianan A., additional, Ako, Beranger A., additional, Koui, Tossea S., additional, Assohoun, Stanislas E., additional, Gbessi, Eric A., additional, N’guessan, Landry T., additional, Tuo, Karim, additional, Beourou, Sylvain, additional, Assi, Serge-Brice, additional, Yapo, Francis A., additional, Sanogo, Ibrahima, additional, and Jambou, Ronan, additional

Published
2022
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16. Sensors for the CDF Run2b silicon detector

Author

Akimoto, T., Aoki, M., Azzi, P., Bacchetta, N., Behari, S., Benjamin, D., Bisello, D., Bolla, G., Booth, P., Bortoletto, D., Burghard, A., Busetto, G., Cabrera, S., Canepa, A., Cardoso, G., Chertok, M., Ciobanu, C.I., Cooke, P., Derylo, G., Fang, I., Feng, E.J., Fernandez, J.P., Flaugher, B., Freeman, J., Galtieri, L., Galyardt, J., Garcia-Sciveres, M., Giurgiu, G., Gorelov, I., Haber, C., Hale, D., Hara, K., Harr, R., Hill, C., Hoeferkamp, M., Hoff, J., Holbrook, B., Hong, S.C., Hrycyk, M., Hsiung, T.H., Incandela, J., Jeon, E.J., Joo, K.K., Junk, T., Kahkola, H., Karjalainen, S., Kim, S., Kobayashi, K., Kong, D.J., Krieger, B., Kruse, M., Kyre, S., Lander, R., Landry, T., Lauhakangas, R., Lee, J., Lu, R.-S., Lujan, P.J., Lukens, P., Mandelli, E., Manea, C., Maksimovic, P., Merkel, P., Min, S.N., Moccia, S., Nakamura, Y., Nakano, I., Naoumov, D., Nelson, T., Nord, B., Novak, J., Okusawa, T., Orava, R., Orlov, Y., Osterberg, K., Pantano, D., Pavlicek, V., Pellett, D., Pursley, J., Riipinen, P., Schuyler, B., Seidel, S., Shenai, A., Soha, A., Stuart, D., Tanaka, R., Tavi, M., Von der Lippe, H., Walder, J.-P., Wang, Z., Watje, P., Weber, M., Wester, W., Yamamoto, Kenichi, Yang, Y.C., Yao, W., Yarema, R., Yoshitama, H., Yun, J.C., Zetti, F., Zimmerman, T., Zimmermann, S., and Zucchelli, S.

Subjects
Hamamatsu Photonic Systems -- Product development, Silicon diodes -- Product development, Photographic industry -- Product development, Sensors -- Usage, Business, Electronics, Electronics and electrical industries
Abstract

We describe the characteristics of silicon microstrip sensors fabricated by Hamamatsu Photonics for the CDF Run 2b silicon detector. A total of 953 sensors, including 117 prototype sensors, have been produced and tested. Five sensors were irradiated with neutrons up to 1.4 x [10.sup.14] n/[cm.sup.2] as a part of the sensor quality assurance program. The electrical and mechanical characteristics are found to be superior in all aspects and fulfill our specifications. We comment on charge-up susceptibility of the sensors that employ a (100) crystal structure.

Published
2004

17. CDF Run IIb silicon detector: electrical performance and deadtime-less operation

Author

Akimoto, T., Aoki, M., Azzi, P., Bacchetta, N., Behari, S., Benjamin, D., Bisello, D., Bolla, G., Bortoletto, D., Busetto, G., Cabrera, S., Canepa, A., Cardoso, G., Chertok, M., Ciobanu, C.I., Derylo, G., Fang, I., Feng, E.J., Fernandez, J.P., Flaugher, B., Freeman, J., Galtieri, L., Galyardt, J., Garcia-Sciveres, M., Giurgiu, G., Haber, C., Hale, D., Hara, K., Harr, R., Hill, C., Hoff, J., Holbrook, B., Hong, S.C., Hrycyk, M., Hsiung, T.H., Incandela, J., Jeon, E.J., Joo, K.K., Junk, T., Kahkola, H., Karjalainen, S., Kim, S., Kobayashi, K., Kong, D.J., Krieger, B., Kruse, M., Kuznetsova, N., Kyre, S., Lander, R., Landry, T., Lauhakangas, R., Lee, J., Lu, R.-S., Lujan, P., Lukens, P., Mandelli, E., Manea, C., Maksimovic, P., Merkel, P., Min, S.N., Moccia, S., Nakano, I., Nelson, T., Nord, B., Novak, J., Okusawa, T., Orava, R., Orlov, Y., Osterberg, K., Pantano, D., Pavlicek, V., Pellett, D., Pursley, J., Riipinen, P., Schuyler, B., Shenai, A., Soha, A., Stuart, D., Tanaka, R., Tavi, M., Von der Lippe, H., Walder, J.-P., Wang, Z., Weber, Marc, Wester, W., Yamamoto, Kenichi, Yang, Y.C., Yao, W., Yarema, R., Yun, J.C., Zetti, F., Zimmerman, T., Zimmermann, S., and Zucchelli, S.

Subjects
Nuclear physics -- Research, Detectors, Business, Electronics, Electronics and electrical industries
Abstract

The main building block and readout unit of the planned CDF Run IIb silicon detector is a 'stave,' a highly integrated mechanical, thermal, and electrical structure. One of its characteristic features is a copper-on-Kapton flexible cable for power, high voltage, data transmission, and control signals that is placed directly below the silicon microstrip sensors. The dense packaging makes deadtime-less operation of the stave a challenge since coupling of bus cable activity into the silicon sensors must be suppressed efficiently. The stave design features relevant for deadtime-less operation are discussed. The electrical performance achieved with stave prototypes is presented. Index Terms--CDF, deadtime-less, Run IIb, silicon tracker, SVX4.

Published
2004

19. The CDF Run IIb Silicon Detector: Design, preproduction, and performance

Author

Akimoto, T., Aoki, M., Azzi, P., Bacchetta, N., Behari, S., Benjamin, D., Bisello, D., Bolla, G., Bortoletto, D., Burghard, A., Busetto, G., Cabrera, S., Canepa, A., Cardoso, G., Chertok, M., Ciobanu, C.I., Derylo, G., Fang, I., Feng, E.J., Fernandez, J.P., Flaugher, B., Freeman, J., Galtieri, L., Galyardt, J., Garcia-Sciveres, M., Giurgiu, G., Gorelov, I., Haber, C., Hale, D., Hara, K., Harr, R., Hill, C., Hoeferkamp, M., Hoff, J., Holbrook, B., Hong, S.C., Hrycyk, M., Hsiung, T.H., Incandela, J., Jeon, E.J., Joo, K.K., Junk, T., Kahkola, H., Karjalainen, S., Kim, S., Kobayashi, K., Kong, D.J., Krieger, B., Kruse, M., Kuznetsova, N., Kyre, S., Lander, R., Landry, T., Lauhakangas, R., Lee, J., Lu, R.-S., Lujan, P., Lukens, P., Mandelli, E., Manea, C., Maksimovic, P., Merkel, P., Min, S.N., Moccia, S., Nakano, I., Naoumov, D., Nelson, T., Nord, B., Novak, J., Okusawa, T., Orava, R., Orlov, Y., Osterberg, K., Pantano, D., Pavlicek, V., Pellett, D., Pursley, J., Riipinen, P., Schuyler, B., Seidel, S., Shenai, A., Soha, A., Stuart, D., Tanaka, R., Tavi, M., Von der Lippe, H., Walder, J.-P., Wang, Z., Watje, P., Weber, Marc, Wester, W., Yamamoto, K., Yang, Y.C., Yao, W., Yarema, R., Yun, J.C., Zetti, F., Zimmerman, T., Zimmermann, S., and Zucchelli, S.

Published
2006
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23. Poster Summaries

Author

Gucciardo, Sébastien, primary, Wisniewski, Jean-Pierre, additional, Mak, Lora, additional, Durrant, Marcus, additional, Rathbun, Elizabeth, additional, Brewin, Nick, additional, Suzuki, Akihiro, additional, Akune, Mitsumi, additional, Imagama, Yoshihiro, additional, Osuki, Ken-ichi, additional, Aoki, Toshio, additional, Uchiumi, Toshiki, additional, Abe, Mikiko, additional, Chou, Minxia, additional, Zhou, Junchu, additional, Xie, Bo, additional, Miao, Lihong, additional, Zhou, Kui, additional, Xie, Fuli, additional, Cheng, Xian-Guo, additional, Tajima, Shigeyuki, additional, Kouchi, Hiroshi, additional, Wang, Yanzhang, additional, Yu, Guan-Qiao, additional, Zhu, Jia-Bi, additional, He, Zhishui, additional, Xie, Rong, additional, Terakado, Junko, additional, Yoneyama, Tadakatsu, additional, Fujihara, Shinsuke, additional, Ooki, Y., additional, Banba, M., additional, Yano, K., additional, Maruya, J., additional, Sato, S., additional, Tabata, S., additional, Saeki, K., additional, Hayashi, M., additional, Kawaguchi, M., additional, Izui, K., additional, Hata, S., additional, Deguchi, Y., additional, Checchetka, S.A., additional, Bamba, M., additional, Maeda, D., additional, Ashida, K., additional, Iguchi, K., additional, Nomura, Mika, additional, Thu, Mai Ha, additional, Yokoyama, Tadashi, additional, Hakoyama, Tsuneo, additional, Arima, Yasuhiro, additional, Shimoda, Y., additional, Higashi, Shiro, additional, Yukihiro, Maru, additional, Hiroki, Miwa, additional, Toshihiro, Aono, additional, Hiroshi, Oyaizu, additional, Wei, Hui, additional, Layzell, David B., additional, Du, Bing Hai, additional, Wang, Lei, additional, Qi, Su Wei, additional, Jiang, Ju Quan, additional, Yang, Su Sheng, additional, Cheng, J., additional, Sibley, C. D., additional, Landry, T., additional, Chain, P. S. G., additional, Lehman, S., additional, Golding, G. B., additional, Yuan, Ze-Chun, additional, Morton, Richard A., additional, Zaheer, Rahat, additional, Rybak, Adrian, additional, Finan, Turlough M., additional, Guillén-Navarro, Karina, additional, Araíza, Gisela, additional, Dunn, Michael F., additional, Nakatsukasa, Hiroki, additional, Wen, Jin, additional, Nan, Bei-Yan, additional, O’Gara, Fergal, additional, Yue, Wen, additional, Wen, Bi-Qing, additional, Wang, Yi-Ping, additional, Yao, Shi-Yi, additional, Luo, Li, additional, Har, Katherine J., additional, Becker, Anke, additional, Cheng, Hai-Ping, additional, Sasakura, Fuyuko, additional, and Takenouchi, Katsumi, additional

Published
2005
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25. Low-latency Gravitational-wave Alerts for Multimessenger Astronomy during the Second Advanced LIGO and Virgo Observing Run

Author

Abbott, (Abbott, Bp, Abbott, B. P., (Abbott, R, Abbott, R., (Abbott, Td, Abraham, T. D., (Abraham, S, Acernese, S., (Acernese, F, Ackley, F., (Ackley, K, Adams, K., (Adams, C, Adhikari, C., (Adhikari, Rx, Adya, R. X., (Adya, Vb, Affeldt, V. B., (Affeldt, C, Agathos, C., (Agathos, M, Agatsuma, M., (Agatsuma, K, Aggarwal, K., (Aggarwal, N, Aguiar, N., (Aguiar, Od, Aiello, O. D., (Aiello, L, Ain, L., (Ain, A, Ajith, A., (Ajith, P, Allen, P., (Allen, G, Allocca, G., (Allocca, A, Aloy, A., (Aloy, Ma, Altin, M. A., (Altin, Pa, Amato, P. A., (Amato, A, Ananyeva, A., (Ananyeva, A, Anderson, A., (Anderson, Sb, Anderson, S. B., (Anderson, Wg, Angelova, W. G., (Angelova, Sv, V), S., Antier, (Antier, S, Appert, S., (Appert, S, Arai, S., (Arai, K, Araya, K., (Araya, Mc, Areeda, M. C., (Areeda, Js, Arene, J. S., (Arene, M, Arnaud, M., (Arnaud, N, Ascenzi, N., (Ascenzi, S, Ashton, S., (Ashton, G, Aston, G., (Aston, Sm, Astone, S. M., (Astone, P, Aubin, P., (Aubin, F, Aufmuth, F., (Aufmuth, P, AultONeal, P., (AultONeal, K, Austin, K., (Austin, C, Avendano, C., (Avendano, V, Avila-Alvarez, V), (Avila-Alvarez, A, Babak, A., (Babak, S, Bacon, S., (Bacon, P, Badaracco, P., (Badaracco, F, Bader, F., Mkm, (Bader, Bae, M. K. M., (Bae, S, Baker, S., (Baker, Pt, Baldaccini, P. T., (Baldaccini, F, Ballardin, F., (Ballardin, G, Ballmer, G., (Ballmer, Sw, Banagiri, S. W., (Banagiri, S, Barayoga, S., (Barayoga, Jc, Barclay, J. C., (Barclay, Se, Barish, S. E., (Barish, Bc, Barker, B. C., (Barker, D, Barkett, D., (Barkett, K, Barnum, K., (Barnum, S, Barone, S., (Barone, F, Barr, F., (Barr, B, Barsotti, B., (Barsotti, L, Barsuglia, L., (Barsuglia, M, Barta, M., (Barta, D, Bartlett, D., (Bartlett, J, Bartos, J., (Bartos, I, Bassiri, I), (Bassiri, R, Basti, R., (Basti, A, Bawaj, A., (Bawaj, M, Bayley, M., (Bayley, Jc, Bazzan, J. 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K., Prasad3, J., Prasai48, K., Prasanna129, R., Pratten98, G., Prestegard23, T., Privitera35, S., Prodi95, G. A., Prokhorov61, L. G., Puncken8, O., Punturo40, M., Puppo31, P., Pürrer35, M., Qi23, H., Quetschke103, V., Quinonez33, P. J., Quintero1, E. A., Quitzow-James69, R., Raab44, F. J., Radkins44, H., Radulescu64, N., Raffai105, P., Raja60, S., Rajan60, C., Rajbhandari83, B., Rakhmanov103, M., Ramirez103, K. E., Ramos-Buades98, A., Rana3, Javed, Rao58, K., Rapagnani31, P., Raymond67, V., Razzano18, M., Read26, J., Regimbau32, T., Rei59, L., Reid24, S., Reitze1, D. H., Ren17, W., Ricci31, F., Richardson33, C. J., Richardson1, J. W., Ricker17, P. M., Riles125, K., Rizzo58, M., Robertson1, N. A., Robie43, R., Robinet25, F., Rocchi30, A., Rolland32, L., Rollins1, J. G., Roma69, V. J., Romanelli66, M., Romano4, R., Romel44, C. L., Romie7, J. H., Rose114, K., Rosińska53, D., Rosofsky17, S. G., Ross165, M. P., Rowan43, S., Rüdiger8, A., 180, 9, Ruggi28, P., Rutins166, G., Ryan44, K., Sachdev1, S., Sadecki44, T., Sakellariadou131, M., Salconi28, L., Saleem141, M., Samajdar36, A., Sammut6, L., Sanchez1, E. J., Sanchez1, L. E., Sanchis-Gual20, N., Sandberg44, V., Sanders41, J. R., Santiago34, K. A., Sarin6, N., Sassolas22, B., Saulson41, P. R., Sauter125, O., Savage44, R. L., Schale69, P., Scheel45, M., Scheuer58, J., Schmidt63, P., Schnabel139, R., Schofield69, R. M. S., Schönbeck139, A., Schreiber8, E., Schulte8, B. W., Schutz67, B. F., Schwalbe33, S. G., Scott43, J., Scott21, S. M., Seidel17, E., Sellers7, D., Sengupta167, A. S., Sennett35, N., Sentenac28, D., Sequino14, V., Sergeev134, A., Setyawati8, Y., Shaddock21, D. A., Shaffer44, T., Shahriar58, M. S., Shaner110, M. B., Shao35, L., Sharma60, P., Shawhan75, P., Shen17, H., Shink168, R., Shoemaker12, D. H., Shoemaker76, D. M., Shyamsundar60, S., Siellez76, K., Sieniawska53, M., Sigg44, D., Silva13, A. D., Singer79, L. P., Singh73, N., Singhal14, A., Sintes98, A. M., Sitmukhambetov103, S., Skliris67, V., Slagmolen21, B. J. J., Slaven-Blair62, T. J., Smith26, J. R., Smith6, R. J. E., Somala169, S., Son137, E. J., Sorazu43, B., Sorrentino59, F., Souradeep3, T., Sowell83, E., Spencer43, A. P., Srivastava106, A. K., Srivastava41, V., Staats58, K., Stachie64, C., Standke8, M., Steer27, D. A., Steinke8, M., Steinlechner43, J., Steinlechner139, S., Steinmeyer8, D., Stevenson152, S. P., Stocks48, D., Stone103, R., Stops11, D. J., Strain43, K. A., Stratta71, G., Strigin61, S. E., Strunk44, A., Sturani170, R., Stuver171, A. L., Sudhir12, V., Summerscales172, T. Z., Sun1, L., Sunil106, S., Suresh3, J., Sutton67, P. J., Swinkels36, B. L., Szczepańczyk33, M. J., Tacca36, M., Tait43, S. C., Talbot6, C., Talukder69, D., Tanner47, D. B., Tápai122, M., Taracchini35, A., Tasson93, J. D., Taylor1, R., Thies8, F., Thomas7, M., Thomas44, P., Thondapu60, S. R., Thorne7, K. A., Thrane6, E., Tiwari95, Shubhanshu, Tiwari123, Srishti, Tiwari67, V., Toland43, K., Tonelli18, M., Tornasi43, Z., Torres-Forné173, A., Torrie1, C. I., Töyrä11, D., Travasso28, F., Traylor7, G., Tringali73, M. C., Trovato27, A., Trozzo19, L., Trudeau1, R., Tsang36, K. W., Tse12, M., Tso45, R., Tsukada81, L., Tsuna81, D., Tuyenbayev103, D., Ueno81, K., Ugolini175, D., Unnikrishnan123, C. S., Urban2, A. L., Usman67, S. A., Vahlbruch9, H., Vajente1, G., Valdes2, G., van Bakel36, N., van Beuzekom36, M., van den Brand36, J. F. J., Van Den Broeck36, C., Vander-Hyde41, D. C., van Heijningen62, J. V., van der Schaaf36, L., van Veggel43, A. A., Vardaro50, M., Varma45, V., Vass1, S., Vasúth46, M., Vecchio11, A., Vedovato51, G., Veitch43, J., Veitch54, P. J., Venkateswara165, K., Venugopalan1, G., Verkindt32, D., Vetrano71, F., Viceré71, A., Viets23, A. D., Vine166, D. J., Vinet64, J. -Y., Vitale12, S., Vo41, T., Vocca39, H., Vorvick44, C., Vyatchanin61, S. P., Wade1, A. R., Wade114, L. E., Wade114, M., Walet36, R., Walker26, M., Wallace1, L., Walsh23, S., Wang14, G., Wang11, H., Wang125, J. Z., Wang103, W. H., Wang90, Y. F., Ward21, R. L., Warden33, Z. A., Warner44, J., Was32, M., Watchi99, J., Weaver44, B., Wei8, L. -W., Weinert8, M., Weinstein1, A. J., Weiss12, R., Wellmann8, F., Wen62, L., Wessel17, E. K., Weßels8, P., Westhouse33, J. W., Wette21, K., Whelan57, J. T., Whiting47, B. F., Whittle12, C., Wilken8, D. M., Williams43, D., Williamson36, A. R., Willis1, J. L., Willke8, B., Wimmer8, M. H., Winkler8, W., Wipf1, C. C., Wittel8, H., Woan43, G., Woehler8, J., Wofford57, J. K., Worden44, J., Wright43, J. L., Wu8, D. S., Wysocki57, D. M., Xiao1, L., Yamamoto1, H., Yancey75, C. C., Yang113, L., Yap21, M. J., Yazback47, M., Yeeles67, D. W., Yu12, Hang, Yu12, Haocun, Yuen90, S. H. R., Yvert32, M., Zadrożny103, A. K., Zanolin33, M., Zelenova28, T., Zendri51, J. -P., Zevin58, M., Zhang62, J., Zhang1, L., Zhang43, T., Zhao62, C., Zhou58, M., Zhou58, Z., Zimmerman177, A. B., Zhu6, X. J., Zucker1, M. E., Zweizig, and J., Laboratoire des matériaux avancés (LMA), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Astrophysique Relativiste Théories Expériences Métrologie Instrumentation Signaux (ARTEMIS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut des Fonctions Optiques pour les Technologies de l'informatiON (Institut FOTON), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des 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LIGO Scientific, Virgo, Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire d'Annecy de Physique des Particules (LAPP/Laboratoire d'Annecy-le-Vieux de Physique des Particules), Université Nice Sophia Antipolis (... - 2019) (UNS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-Université Bretagne Loire (UBL)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris)-Collège de France (CdF)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), ESPCI ParisTech, Institut des Hautes Etudes Scientifiques (IHES), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Abbott, Bp, Abbott, R, Abbott, Td, Abraham, S, Acernese, F, Ackley, K, Adams, C, Adhikari, Rx, Adya, Vb, Affeldt, C, Agathos, M, Agatsuma, K, Aggarwal, N, Aguiar, Od, Aiello, L, Ain, A, Ajith, P, Allen, G, Allocca, A, Aloy, Ma, Altin, Pa, Amato, A, Ananyeva, A, Anderson, Sb, Anderson, Wg, Angelova, Sv, Antier, S, Appert, S, Arai, K, Araya, Mc, Areeda, J, Arene, M, Arnaud, N, Ascenzi, S, Ashton, G, Aston, Sm, Astone, P, Aubin, F, Aufmuth, P, Aultoneal, K, Austin, C, Avendano, V, Avila-Alvarez, A, Babak, S, Bacon, P, Badaracco, F, Bader, Mkm, Bae, S, Baker, Pt, Baldaccini, F, Ballardin, G, Ballmer, Sw, Banagiri, S, Barayoga, Jc, Barclay, Se, Barish, Bc, Barker, D, Barkett, K, Barnum, S, Barone, F, Barr, B, Barsotti, L, Barsuglia, M, Barta, D, Bartlett, J, Bartos, I, Bassiri, R, Basti, A, Bawaj, M, Bayley, Jc, Bazzan, M, Becsy, B, Bejger, M, Belahcene, I, Bell, A, Beniwal, D, Berger, Bk, Bergmann, G, Bernuzzi, S, Bero, Jj, Berry, Cpl, Bersanetti, D, Bertolini, A, Betzwieser, J, Bhandare, R, Bidler, J, Bilenko, Ia, Bilgili, Sa, Billingsley, G, Birch, J, Birney, R, Birnholtz, O, Biscans, S, Biscoveanu, S, Bisht, A, Bitossi, M, Bizouard, Ma, Blackburn, Jk, Blair, Cd, Blair, Dg, Blair, Rm, Bloemen, S, Bode, N, Boer, M, Boetzel, Y, Bogaert, G, Bondu, F, Bonilla, E, Bonnand, R, Booker, P, Boom, Ba, Booth, Cd, Bork, R, Boschi, V, Bose, S, Bossie, K, Bossilkov, V, Bosveld, J, Bouffanais, Y, Bozzi, A, Bradaschia, C, Brady, Pr, Bramley, A, Branchesi, M, Brau, Je, Briant, T, Briggs, Jh, Brighenti, F, Brillet, A, Brinkmann, M, Brisson, V, Brockill, P, Brooks, Af, Brown, Dd, Brunett, S, Buikema, A, Bulik, T, Bulten, Hj, Buonanno, A, Buskulic, D, Buy, C, Byer, Rl, Cabero, M, Cadonati, L, Cagnoli, G, Cahillane, C, Bustillo, Jc, Callister, Ta, Calloni, E, Camp, Jb, Campbell, Wa, Canepa, M, Cannon, Kc, Cao, H, Cao, J, Capocasa, E, Carbognani, F, Caride, S, Carney, Mf, Carullo, G, Diaz, Jc, Casentini, C, Caudill, S, Cavaglia, M, Cavalier, F, Cavalieri, R, Cella, G, Cerda-Duran, P, Cerretani, G, Cesarini, E, Chaibi, O, Chakravarti, K, Chamberlin, Sj, Chan, M, Chao, S, Charlton, P, Chase, Ea, Chassande-Mottin, E, Chatterjee, D, Chaturvedi, M, Cheeseboro, Bd, Chen, Hy, Chen, X, Chen, Y, Cheng, Hp, Cheong, Ck, Chia, Hy, Chincarini, A, Chiummo, A, Cho, G, Cho, H, Cho, M, Christensen, N, Chu, Q, Chua, S, Chung, Kw, Chung, S, Ciani, G, Ciobanu, Aa, Ciolfi, R, Cipriano, F, Cirone, A, Clara, F, Clark, Ja, Clearwater, P, Cleva, F, Cocchieri, C, Coccia, E, Cohadon, Pf, Cohen, D, Colgan, R, Colleoni, M, Collette, Cg, Collins, C, Cominsky, Lr, Constancio, M, Conti, L, Cooper, Sj, Corban, P, Corbitt, Tr, Cordero-Carrion, I, Corley, Kr, Cornish, N, Corsi, A, Cortese, S, Costa, Ca, Cotesta, R, Coughlin, Mw, Coughlin, Sb, Coulon, Jp, Countryman, St, Couvares, P, Covas, Pb, Cowan, Ee, Coward, Dm, Cowart, Mj, Coyne, Dc, Coyne, R, Creighton, Jde, Creighton, Td, Cripe, J, Croquette, M, Crowder, Sg, Cullen, Tj, Cumming, A, Cunningham, L, Cuoco, E, Dal Canton, T, Dalya, G, Danilishin, Sl, D'Antonio, S, Danzmann, K, Dasgupta, A, Costa, Cfd, Datrier, Leh, Dattilo, V, Dave, I, Davier, M, Davis, D, Daw, Ej, Debra, D, Deenadayalan, M, Degallaix, J, De Laurentis, M, Deleglise, S, Del Pozzo, W, Demarchi, Lm, Demos, N, Dent, T, De Pietri, R, Derby, J, De Rosa, R, De Rossi, C, Desalvo, R, de Varona, O, Dhurandhar, S, Diaz, Mc, Dietrich, T, Di Fiore, L, Di Giovanni, M, Di Girolamo, T, Di Lieto, A, Ding, B, Di Pace, S, Di Palma, I, Di Renzo, F, Dmitriev, A, Doctor, Z, Donovan, F, Dooley, Kl, Doravari, S, Dorrington, I, Downes, Tp, Drago, M, Driggers, Jc, Du, Z, Ducoin, Jg, Dupej, P, Dwyer, Se, Easter, Pj, Edo, Tb, Edwards, Mc, Effler, A, Ehrens, P, Eichholz, J, Eikenberry, S, Eisenmann, M, Eisenstein, Ra, Essick, Rc, Estelles, H, Estevez, D, Etienne, Zb, Etzel, T, Evans, M, Evans, Tm, Fafone, V, Fair, H, Fairhurst, S, Fan, X, Farinon, S, Farr, B, Farr, Wm, Fauchon-Jones, Ej, Favata, M, Fays, M, Fazio, M, Fee, C, Feicht, J, Fejer, Mm, Feng, F, Fernandez-Galiana, A, Ferrante, I, Ferreira, Ec, Ferreira, Ta, Ferrini, F, Fidecaro, F, Fiori, I, Fiorucci, D, Fishbach, M, Fisher, Rp, Fishner, Jm, Fitz-Axen, M, Flaminio, R, Fletcher, M, Flynn, E, Fong, H, Font, Ja, Forsyth, Pwf, Fournier, Jd, Frasca, S, Frasconi, F, Frei, Z, Freise, A, Frey, R, Frey, V, Fritschel, P, Frolov, Vv, Fulda, P, Fyffe, M, Gabbard, Ha, Gadre, Bu, Gaebel, Sm, Gair, Jr, Gammaitoni, L, Ganija, Mr, Gaonkar, Sg, Garcia, A, Garcia-Quiros, C, Garufi, F, Gateley, B, Gaudio, S, Gaur, G, Gayathri, V, Gemme, G, Genin, E, Gennai, A, George, D, George, J, Gergely, L, Germain, V, Ghonge, S, Ghosh, A, Ghosh, S, Giacomazzo, B, Giaime, Ja, Giardina, Kd, Giazotto, A, Gill, K, Giordano, G, Glover, L, Godwin, P, Goetz, E, Goetz, R, Goncharov, B, Gonzalez, G, Castro, Jmg, Gopakumar, A, Gorodetsky, Ml, Gossan, Se, Gosselin, M, Gouaty, R, Grado, A, Graef, C, Granata, M, Grant, A, Gras, S, Grassia, P, Gray, C, Gray, R, Greco, G, Green, Ac, Green, R, Gretarsson, Em, Groot, P, Grote, H, Grunewald, S, Gruning, P, Guidi, Gm, Gulati, Hk, Guo, Y, Gupta, A, Gupta, Mk, Gustafson, Ek, Gustafson, R, Haegel, L, Halim, O, Hall, Br, Hall, Ed, Hamilton, Ez, Hammond, G, Haney, M, Hanke, Mm, Hanks, J, Hanna, C, Hannuksela, Oa, Hanson, J, Hardwick, T, Haris, K, Harms, J, Harry, Gm, Harry, Iw, Haster, Cj, Haughian, K, Hayes, Fj, Healy, J, Heidmann, A, Heintze, Mc, Heitmann, H, Hello, P, Hemming, G, Hendry, M, Heng, I, Hennig, J, Heptonstall, Aw, Vivanco, Fh, Heurs, M, Hild, S, Hinderer, T, Hoak, D, Hochheim, S, Hofman, D, Holgado, Am, Holland, Na, Holt, K, Holz, De, Hopkins, P, Horst, C, Hough, J, Howell, Ej, Hoy, Cg, Hreibi, A, Huerta, Ea, Huet, D, Hughey, B, Hulko, M, Husa, S, Huttner, Sh, Huynh-Dinh, T, Idzkowski, B, Iess, A, Ingram, C, Inta, R, Intini, G, Irwin, B, Isa, Hn, Isac, Jm, Isi, M, Iyer, Br, Izumi, K, Jacqmin, T, Jadhav, Sj, Jani, K, Janthalur, Nn, Jaranowski, P, Jenkins, Ac, Jiang, J, Johnson, D, Jones, Aw, Jones, Di, Jones, R, Jonker, Rjg, Ju, L, Junker, J, Kalaghatgi, Cv, Kalogera, V, Kamai, B, Kandhasamy, S, Kang, G, Kanner, Jb, Kapadia, Sj, Karki, S, Karvinen, K, Kashyap, R, Kasprzack, M, Katsanevas, S, Katsavounidis, E, Katzman, W, Kaufer, S, Kawabe, K, Keerthana, Nv, Kefelian, F, Keitel, D, Kennedy, R, Key, J, Khalili, Fy, Khan, H, Khan, I, Khan, S, Khan, Z, Khazanov, Ea, Khursheed, M, Kijbunchoo, N, Kim, C, Kim, Jc, Kim, K, Kim, W, Kim, Ym, Kimball, C, King, Ej, King, Pj, Kinley-Hanlon, M, Kirchhoff, R, Kissel, J, Kleybolte, L, Klika, Jh, Klimenko, S, Knowles, Td, Koch, P, Koehlenbeck, Sm, Koekoek, G, Koley, S, Kondrashov, V, Kontos, A, Koper, N, Korobko, M, Korth, Wz, Kowalska, I, Kozak, Db, Kringel, V, Krishnendu, N, Krolak, A, Kuehn, G, Kumar, A, Kumar, P, Kumar, R, Kumar, S, Kuo, L, Kutynia, A, Kwang, S, Lackey, Bd, Lai, Kh, Lam, Tl, Landry, M, Lane, Bb, Lang, Rn, Lange, J, Lantz, B, Lanza, Rk, Lartaux-Vollard, A, Lasky, Pd, Laxen, M, Lazzarini, A, Lazzaro, C, Leaci, P, Leavey, S, Lecoeuche, Yk, Lee, Ch, Lee, Hk, Lee, Hm, Lee, Hw, Lee, J, Lee, K, Lehmann, J, Lenon, A, Leroy, N, Letendre, N, Levin, Y, Li, J, Li, Kjl, Li, Tgf, Li, X, Lin, F, Linde, F, Linker, Sd, Littenberg, Tb, Liu, J, Liu, X, Lo, Rkl, Lockerbie, Na, London, Lt, Longo, A, Lorenzini, M, Loriette, V, Lormand, M, Losurdo, G, Lough, Jd, Lousto, Co, Lovelace, G, Lower, Me, Luck, H, Lumaca, D, Lundgren, Ap, Lynch, R, Ma, Y, Macas, R, Macfoy, S, Macinnis, M, Macleod, Dm, Macquet, A, Magana-Sandoval, F, Zertuche, Lm, Magee, Rm, Majorana, E, Maksimovic, I, Malik, A, Man, N, Mandic, V, Mangano, V, Mansell, Gl, Manske, M, Mantovani, M, Marchesoni, F, Marion, F, Marka, S, Marka, Z, Markakis, C, Markosyan, A, Markowitz, A, Maros, E, Marquina, A, Marsat, S, Martelli, F, Martin, Iw, Martin, Rm, Martynov, Dv, Mason, K, Massera, E, Masserot, A, Massinger, Tj, Masso-Reid, M, Mastrogiovanni, S, Matas, A, Matichard, F, Matone, L, Mavalvala, N, Mazumder, N, Mccann, Jj, Mccarthy, R, Mcclelland, De, Mccormick, S, Mcculler, L, Mcguire, Sc, Mciver, J, Mcmanus, Dj, Mcrae, T, Mcwilliams, St, Meacher, D, Meadors, Gd, Mehmet, M, Mehta, Ak, Meidam, J, Melatos, A, Mendell, G, Mercer, Ra, Mereni, L, Merilh, El, Merzougui, M, Meshkov, S, Messenger, C, Messick, C, Metzdorff, R, Meyers, Pm, Miao, H, Michel, C, Middleton, H, Mikhailov, Ee, Milano, L, Miller, Al, Miller, A, Millhouse, M, Mills, Jc, Milovich-Goff, Mc, Minazzoli, O, Minenkov, Y, Mishkin, A, Mishra, C, Mistry, T, Mitra, S, Mitrofanov, Vp, Mitselmakher, G, Mittleman, R, Mo, G, Moffa, D, Mogushi, K, Mohapatra, Srp, Montani, M, Moore, Cj, Moraru, D, Moreno, G, Morisaki, S, Mours, B, Mow-Lowry, Cm, Mukherjee, A, Mukherjee, D, Mukherjee, S, Mukund, N, Mullavey, A, Munch, J, Muniz, Ea, Muratore, M, Murray, Pg, Nagar, A, Nardecchia, I, Naticchioni, L, Nayak, Rk, Neilson, J, Nelemans, G, Nelson, Tjn, Nery, M, Neunzert, A, Ng, Ky, Ng, S, Nguyen, P, Nichols, D, Nissanke, S, Nitz, A, Nocera, F, North, C, Nuttall, Lk, Obergaulinger, M, Oberling, J, O'Brien, Bd, O'Dea, Gd, Ogin, Gh, Oh, Jj, Oh, Sh, Ohme, F, Ohta, H, Okada, Ma, Oliver, M, Oppermann, P, Oram, Rj, O'Reilly, B, Ormiston, Rg, Ortega, Lf, O'Shaughnessy, R, Ossokine, S, Ottaway, Dj, Overmier, H, Owen, Bj, Pace, Ae, Pagano, G, Page, Ma, Pai, A, Pai, Sa, Palamos, Jr, Palashov, O, Palomba, C, Pal-Singh, A, Pan, Hw, Pang, B, Pang, Pth, Pankow, C, Pannarale, F, Pant, Bc, Paoletti, F, Paoli, A, Parida, A, Parker, W, Pascucci, D, Pasqualetti, A, Passaquieti, R, Passuello, D, Patil, M, Patricelli, B, Pearlstone, Bl, Pedersen, C, Pedraza, M, Pedurand, R, Pele, A, Penn, S, Perez, Cj, Perreca, A, Pfeiffer, Hp, Phelps, M, Phukon, K, Piccinni, Oj, Pichot, M, Piergiovanni, F, Pillant, G, Pinard, L, Pirello, M, Pitkin, M, Poggiani, R, Pong, Dyt, Ponrathnam, S, Popolizio, P, Porter, Ek, Powell, J, Prajapati, Ak, Prasad, J, Prasai, K, Prasanna, R, Pratten, G, Prestegard, T, Privitera, S, Prodi, Ga, Prokhorov, Lg, Puncken, O, Punturo, M, Puppo, P, Purrer, M, Qi, H, Quetschke, V, Quinonez, Pj, Quintero, Ea, Quitzow-James, R, Raab, Fj, Radkins, H, Radulescu, N, Raffai, P, Raja, S, Rajan, C, Rajbhandari, B, Rakhmanov, M, Ramirez, Ke, Ramos-Buades, A, Rana, J, Rao, K, Rapagnani, P, Raymond, V, Razzano, M, Read, J, Regimbau, T, Rei, L, Reid, S, Reitze, Dh, Ren, W, Ricci, F, Richardson, Cj, Richardson, Jw, Ricker, Pm, Riles, K, Rizzo, M, Robertson, Na, Robie, R, Robinet, F, Rocchi, A, Rolland, L, Rollins, Jg, Roma, Vj, Romanelli, M, Romano, R, Romel, Cl, Romie, Jh, Rose, K, Rosinska, D, Rosofsky, Sg, Ross, Mp, Rowan, S, Rudiger, A, Ruggi, P, Rutins, G, Ryan, K, Sachdev, S, Sadecki, T, Sakellariadou, M, Salconi, L, Saleem, M, Samajdar, A, Sammut, L, Sanchez, Ej, Sanchez, Le, Sanchis-Gual, N, Sandberg, V, Sanders, Jr, Santiago, Ka, Sarin, N, Sassolas, B, Saulson, Pr, Sauter, O, Savage, Rl, Schale, P, Scheel, M, Scheuer, J, Schmidt, P, Schnabel, R, Schofield, Rm, Schonbeck, A, Schreiber, E, Schulte, Bw, Schutz, Bf, Schwalbe, Sg, Scott, J, Scott, Sm, Seidel, E, Sellers, D, Sengupta, A, Sennett, N, Sentenac, D, Sequino, V, Sergeev, A, Setyawati, Y, Shaddock, Da, Shaffer, T, Shahriar, M, Shaner, Mb, Shao, L, Sharma, P, Shawhan, P, Shen, H, Shink, R, Shoemaker, Dh, Shoemaker, Dm, Shyamsundar, S, Siellez, K, Sieniawska, M, Sigg, D, Silva, Ad, Singer, Lp, Singh, N, Singhal, A, Sintes, Am, Sitmukhambetov, S, Skliris, V, Slagmolen, Bjj, Slaven-Blair, Tj, Smith, Jr, Smith, Rje, Somala, S, Son, Ej, Sorazu, B, Sorrentino, F, Souradeep, T, Sowell, E, Spencer, Ap, Srivastava, Ak, Srivastava, V, Staats, K, Stachie, C, Standke, M, Steer, Da, Steinke, M, Steinlechner, J, Steinlechner, S, Steinmeyer, D, Stevenson, Sp, Stocks, D, Stone, R, Stops, Dj, Strain, Ka, Stratta, G, Strigin, Se, Strunk, A, Sturani, R, Stuver, Al, Sudhir, V, Summerscales, Tz, Sun, L, Sunil, S, Suresh, J, Sutton, Pj, Swinkels, Bl, Szczepanczyk, Mj, Tacca, M, Tait, Sc, Talbot, C, Talukder, D, Tanner, Db, Tapai, M, Taracchini, A, Tasson, Jd, Taylor, R, Thies, F, Thomas, M, Thomas, P, Thondapu, Sr, Thorne, Ka, Thrane, E, Tiwari, S, Tiwari, V, Toland, K, Tonelli, M, Tornasi, Z, Torres-Forne, A, Torrie, Ci, Toyra, D, Travasso, F, Traylor, G, Tringali, Mc, Trovato, A, Trozzo, L, Trudeau, R, Tsang, Kw, Tse, M, Tso, R, Tsukada, L, Tsuna, D, Tuyenbayev, D, Ueno, K, Ugolini, D, Unnikrishnan, C, Urban, Al, Usman, Sa, Vahlbruch, H, Vajente, G, Valdes, G, van Bakel, N, van Beuzekom, M, van den Brand, Jfj, Van den Broeck, C, Vander-Hyde, Dc, van Heijningen, Jv, van der Schaaf, L, van Veggel, Aa, Vardaro, M, Varma, V, Vass, S, Vasuth, M, Vecchio, A, Vedovato, G, Veitch, J, Veitch, Pj, Venkateswara, K, Venugopalan, G, Verkindt, D, Vetrano, F, Vicere, A, Viets, Ad, Vine, Dj, Vinet, Jy, Vitale, S, Vo, T, Vocca, H, Vorvick, C, Vyatchanin, Sp, Wade, Ar, Wade, Le, Wade, M, Walet, R, Walker, M, Wallace, L, Walsh, S, Wang, G, Wang, H, Wang, Jz, Wang, Wh, Wang, Yf, Ward, Rl, Warden, Za, Warner, J, Was, M, Watchi, J, Weaver, B, Wei, Lw, Weinert, M, Weinstein, Aj, Weiss, R, Wellmann, F, Wen, L, Wessel, Ek, Wessels, P, Westhouse, Jw, Wette, K, Whelan, Jt, Whiting, Bf, Whittle, C, Wilken, Dm, Williams, D, Williamson, Ar, Willis, Jl, Willke, B, Wimmer, Mh, Winkler, W, Wipf, Cc, Wittel, H, Woan, G, Woehler, J, Wofford, Jk, Worden, J, Wright, Jl, Wu, D, Wysocki, Dm, Xiao, L, Yamamoto, H, Yancey, Cc, Yang, L, Yap, Mj, Yazback, M, Yeeles, Dw, Yu, H, Yu, Hc, Yuen, Shr, Yvert, M, Zadrozny, Ak, Zanolin, M, Zelenova, T, Zendri, Jp, Zevin, M, Zhang, J, Zhang, L, Zhang, T, Zhao, C, Zhou, M, Zhou, Z, Zimmerman, Ab, Zhu, Xj, Zucker, Me, Zweizig, J, Abbott, B, Abbott, T, Adhikari, R, Adya, V, Aguiar, O, Aloy, M, Altin, P, Anderson, S, Anderson, W, Angelova, S, Araya, M, Aston, S, Bader, M, Baker, P, Ballmer, S, Barayoga, J, Barclay, S, Barish, B, Bayley, J, Berger, B, Bero, J, Berry, C, Bilenko, I, Bilgili, S, Bizouard, M, Blackburn, J, Blair, C, Blair, D, Blair, R, Boom, B, Booth, C, Brady, P, Brau, J, Briggs, J, Brooks, A, Brown, D, Bulten, H, Byer, R, Bustillo, J, Callister, T, Camp, J, Campbell, W, Cannon, K, Carney, M, Diaz, J, Chamberlin, S, Chase, E, Cheeseboro, B, Chen, H, Cheng, H, Cheong, C, Chia, H, Chung, K, Ciobanu, A, Clark, J, Cohadon, P, Collette, C, Cominsky, L, Cooper, S, Corbitt, T, Corley, K, Costa, C, Coughlin, M, Coughlin, S, Coulon, J, Countryman, S, Covas, P, Cowan, E, Coward, D, Cowart, M, Coyne, D, Creighton, J, Creighton, T, Crowder, S, Cullen, T, Canton, T, Danilishin, S, Datrier, L, Daw, E, Pozzo, W, Demarchi, L, De Varona, O, Diaz, M, Fiore, L, Giovanni, M, Girolamo, T, Lieto, A, Pace, S, Palma, I, Renzo, F, Dooley, K, Downes, T, Driggers, J, Ducoin, J, Dwyer, S, Easter, P, Edo, T, Edwards, M, Eisenstein, R, Essick, R, Etienne, Z, Evans, T, Farr, W, Fauchon-Jones, E, Fejer, M, Ferreira, E, Ferreira, T, Fisher, R, Fishner, J, Font, J, Forsyth, P, Fournier, J, Frolov, V, Gabbard, H, Gadre, B, Gaebel, S, Gair, J, Ganija, M, Gaonkar, S, Giaime, J, Giardina, K, Castro, J, Gorodetsky, M, Gossan, S, Green, A, Gretarsson, E, Guidi, G, Gulati, H, Gupta, M, Gustafson, E, Hall, B, Hall, E, Hamilton, E, Hanke, M, Hannuksela, O, Harry, G, Harry, I, Haster, C, Hayes, F, Heintze, M, Heptonstall, A, Vivanco, F, Holgado, A, Holland, N, Holz, D, Howell, E, Hoy, C, Huerta, E, Huttner, S, Isa, H, Isac, J, Iyer, B, Jadhav, S, Janthalur, N, Jenkins, A, Jones, A, Jones, D, Jonker, R, Kalaghatgi, C, Kanner, J, Kapadia, S, Keerthana, N, Khalili, F, Khazanov, E, Kim, J, Kim, Y, King, E, King, P, Klika, J, Knowles, T, Koehlenbeck, S, Korth, W, Kozak, D, Lackey, B, Lai, K, Lam, T, Lane, B, Lang, R, Lanza, R, Lasky, P, Lecoeuche, Y, Lee, C, Lee, H, Li, K, Li, T, Linker, S, Littenberg, T, Lo, R, Lockerbie, N, London, L, Lough, J, Lousto, C, Lower, M, Lundgren, A, Macleod, D, Zertuche, L, Magee, R, Mansell, G, Martin, I, Martin, R, Martynov, D, Massinger, T, Mccann, J, Mcclelland, D, Mcguire, S, Mcmanus, D, Mcwilliams, S, Meadors, G, Mehta, A, Mercer, R, Merilh, E, Meyers, P, Mikhailov, E, Mills, J, Milovich-Goff, M, Mitrofanov, V, Mohapatra, S, Moore, C, Mow-Lowry, C, Muniz, E, Murray, P, Nayak, R, Nelson, T, Ng, K, Nuttall, L, O'Brien, B, O'Dea, G, Ogin, G, Oh, J, Oh, S, Okada, M, Oram, R, Ormiston, R, Ortega, L, Ottaway, D, Owen, B, Pace, A, Page, M, Pai, S, Palamos, J, Pan, H, Pang, P, Pant, B, Pearlstone, B, Perez, C, Pfeiffer, H, Piccinni, O, Pong, D, Porter, E, Prajapati, A, Prodi, G, Prokhorov, L, Quinonez, P, Quintero, E, Raab, F, Ramirez, K, Reitze, D, Richardson, C, Richardson, J, Ricker, P, Robertson, N, Rollins, J, Roma, V, Romel, C, Romie, J, Rosofsky, S, Ross, M, Sanchez, E, Sanchez, L, Sanders, J, Santiago, K, Saulson, P, Savage, R, Schofield, R, Schulte, B, Schutz, B, Schwalbe, S, Scott, S, Shaddock, D, Shaner, M, Shoemaker, D, Silva, A, Singer, L, Sintes, A, Slagmolen, B, Slaven-Blair, T, Smith, J, Smith, R, Son, E, Spencer, A, Srivastava, A, Steer, D, Stevenson, S, Stops, D, Strain, K, Strigin, S, Stuver, A, Summerscales, T, Sutton, P, Swinkels, B, Szczepanczyk, M, Tait, S, Tanner, D, Tasson, J, Thondapu, S, Thorne, K, Torrie, C, Tringali, M, Tsang, K, Urban, A, Usman, S, Van Bakel, N, Van Beuzekom, M, Van Den Brand, J, Broeck, C, Vander-Hyde, D, Van Heijningen, J, Van Der Schaaf, L, Van Veggel, A, Veitch, P, Viets, A, Vine, D, Vinet, J, Vyatchanin, S, Wade, A, Wade, L, Wang, J, Wang, W, Wang, Y, Ward, R, Warden, Z, Wei, L, Weinstein, A, Wessel, E, Westhouse, J, Whelan, J, Whiting, B, Wilken, D, Williamson, A, Willis, J, Wimmer, M, Wipf, C, Wofford, J, Wright, J, Wysocki, D, Yancey, C, Yap, M, Yeeles, D, Yuen, S, Zadrozny, A, Zendri, J, Zimmerman, A, Zhu, X, Zucker, M, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National de la Recherche Scientifique (CNRS)-Observatoire de la Côte d'Azur, Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)-École Nationale Supérieure des Sciences Appliquées et de Technologie (ENSSAT)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Fédération de recherche du Département de physique de l'Ecole Normale Supérieure - ENS Paris (FRDPENS), Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Collège de France (CdF (institution)), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), (Astro)-Particles Physics, The LIGO Scientific Collaboration, The Virgo Collaboration, IoP (FNWI), and Astroparticle Physics (IHEF, IoP, FNWI)

Subjects
010504 meteorology & atmospheric sciences, data acquisition, Astronomy, 01 natural sciences, black hole, optical, LIGO, gravitational waves, methods: data analysis, gravitational wave, 010303 astronomy & astrophysics, QC, QB, High Energy Astrophysical Phenomena (astro-ph.HE), Settore FIS/01, astro-ph.HE, Physics, NUCLEOSYNTHESIS, radio wave, COMPACT BINARIES, EJECTION, gravitational waves, neutron stars, Physical Sciences, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, on-line, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, NEUTRON-STAR MERGERS, gamma ray: burst, Astronomy & Astrophysics, X-ray, General Relativity and Quantum Cosmology, SDG 17 - Partnerships for the Goals, RAY BURSTS, 0103 physical sciences, data analysis [methods], STFC, 0105 earth and related environmental sciences, Science & Technology, Gravitational wave, gravitational radiation, Online identification, RCUK, Astronomy and Astrophysics, messenger, Neutron star, VIRGO, electromagnetic, Physics and Astronomy, Space and Planetary Science, RADIATION, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Gamma-ray burst, neutron star: coalescence
Abstract

Advanced LIGO's second observing run (O2), conducted from November 30, 2016 to August 25, 2017, combined with Advanced Virgo's first observations in August 2017 witnessed the birth of gravitational-wave multi-messenger astronomy. The first ever gravitational-wave detection from the coalescence of two neutron stars, GW170817, and its gamma-ray counterpart, GRB 170817A, led to an electromagnetic follow-up of the event at an unprecedented scale. Several teams from across the world searched for EM/neutrino counterparts to GW170817, paving the way for the discovery of optical, X-ray, and radio counterparts. In this article, we describe the online identification of gravitational-wave transients and the distribution of gravitational-wave alerts by the LIGO and Virgo collaborations during O2. We also describe the gravitational-wave observables which were sent in the alerts to enable searches for their counterparts. Finally, we give an overview of the online candidate alerts shared with observing partners during O2. Alerts were issued for 14 candidates, six of which have been confirmed as gravitational-wave events associated with the merger of black holes or neutron stars. Eight of the 14 alerts were issued less than an hour after data acquisition., Comment: 27 pages, 5 figures, 3 tables, accepted for publication in the Astrophysical Journal

Published
2019

26. A multi-laboratory evaluation of a common in vitro pepsin digestion assay protocol used in assessing the safety of novel proteins

Author

Thomas, K., Aalbers, M., Bannon, G. A., Bartels, M., Dearman, R. J., Esdaile, D. J., Fu, T. J., Glatt, C. M., Hadfield, N., Hatzos, C., Hefle, S. L., Heylings, J. R., Goodman, R. E., Henry, B., Herouet, C., Holsapple, M., Ladics, G. S., Landry, T. D., MacIntosh, S. C., Rice, E. A., Privalle, L. S., Steiner, H. Y., Teshima, R., van Ree, R., Woolhiser, M., and Zawodny, J.

Published
2004
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27. Iatrogenic spinal cord herniation

Author

Louis Derou, Konan Landry, Michum Kounde, Serge Konan, Landry Teti, André Tokpa, and Aderehime Haidara

Subjects
spinal compression, spinal cord surgery, iatrogenis spinal cord herniation, Neurology. Diseases of the nervous system, RC346-429
Abstract

Introduction: Spinal cord herniation occurs idiopathically or is due to defective or weakened dura mater resulting from iatrogenic or traumatic lesions. Although there have been many reports of idiopathic cases, there are few reports of postoperative iatrogenic spinal cord herniation. The authors describe a rare case of postoperative spinal cord herniation in the cervical spine, with an extensive analysis of reported cases Materials and methods: This article reports a documented case of postoperative spinal cord herniation. The case description is followed by an analysis of the literature. Results: A 67-year-old woman who had cervical laminectomy 3 weeks before for cervical laminectomy, presented with neck pain and torticollis after coughing. The MRI findings showed a cervical medulla herniation with cerebrospinal fluid (CSF) leakage. The patient underwent surgery to reduce the herniation and duroplasty with subsequent complete resolution of symptoms. Over the previous 50 years (1973–2023), 16 post-operative spinal cord herniation cases were reported. The mean patient age was 43.3 years (range 15–67 years). There was a male predominance (80%). The mean onset period after surgery was 292 weeks (range, 1 week to 728 weeks). Clinical symptomatology was polymorphic with non-specific signs. Conclusion: Iatrogenic spinal cord herniation is an extremely rare occurrence after spine surgery. The diagnosis must be evoked in case of any neurological degradation after surgery of the cervical spine, thoracic spine or thoracolumbar junction. The surgical management gives satisfactory clinical results.

Published
2023

28. Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes

Author

Emma Bergsten, Denis Mestivier, Francoise Donnadieu, Thierry Pedron, Caroline Barau, Landry Tsoumtsa Meda, Amel Mettouchi, Emmanuel Lemichez, Olivier Gorgette, Mathias Chamaillard, Amaury Vaysse, Stevenn Volant, Abiba Doukani, Philippe J. Sansonetti, Iradj Sobhani, and Giulia Nigro

Subjects
Colorectal cancer, colonic epithelial primary cells, pathobionts, Parvimonas micra, DNA methylation, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

ABSTRACTRecently, an intestinal dysbiotic microbiota with enrichment in oral cavity bacteria has been described in colorectal cancer (CRC) patients. Here, we characterize and investigate one of these oral pathobionts, the Gram-positive anaerobic coccus Parvimonas micra. We identified two phylotypes (A and B) exhibiting different phenotypes and adhesion capabilities. We observed a strong association of phylotype A with CRC, with its higher abundance in feces and in tumoral tissue compared with the normal homologous colonic mucosa, which was associated with a distinct methylation status of patients. By developing an in vitro hypoxic co-culture system of human primary colonic cells with anaerobic bacteria, we show that P. micra phylotype A alters the DNA methylation profile promoters of key tumor-suppressor genes, oncogenes, and genes involved in epithelial–mesenchymal transition. In colonic mucosa of CRC patients carrying P. micra phylotype A, we found similar DNA methylation alterations, together with significant enrichment of differentially expressed genes in pathways involved in inflammation, cell adhesion, and regulation of actin cytoskeleton, providing evidence of P. micra’s possible role in the carcinogenic process.

Published
2023
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29. Malaria parasite clearance from patients following artemisinin-based combination therapy in Cote d'Ivoire

Author

Toure, O. A., Landry, T. N., Assi, S. B., Kone, A. A., Gbessi, E. A., Ako, B. A., Coulibaly, B., Kone, B., Ouattara, O., Beourou, S., Koffi, A., Remoué, Franck, and Rogier, C.

Subjects
Cote d'Ivoire, parasite clearance, Plasmodium falciparum, ACTs
Abstract

Introduction: Parasite clearance is useful to detect artemisinin resistance. The aim o f this study was to investigate parasite clearance in patients treated with artesunate + amodiaquine (AS + AQ) and artemether + lumefantrine (AL): the two artemisinin-based combination therapies (ACTs) recommended in the first-line treatment of uncomplicated malaria in Cote d'Ivoire. Methods: This study was conducted in Bouake, Cote d'Ivoire, from April to June 2016. Patients aged at least 6 months with uncomplicated malaria and treated with AS + AQ or AL were hospitalized for 3 days, and follow-up assessments were performed on days 3, 7, 14, 21, 28, 35, and 42. Blood smears were collected at the time of screening, pre-dose, and 6-hour intervals following the first dose of administration until two consecutive negative smears were recorded, thereafter at day 3 and follow-up visits. Parasite clearance was determined using the Worldwide Antimalarial Resistance Network's parasite clearance estimator. The primary end points were parasite clearance rate and time. Results: A total of 120 patients (57 in the AS + AQ group and 63 in the AL group) were randomized among 298 patients screened. The median parasite clearance time was 30 hours (IQR, 24-36 hours), for each ACT The median parasite clearance rate had a slope half-life of 2.36 hours (IQR, 1.85-2.88 hours) and 2.23 hours (IQR, 1.74-2.63 hours) for AS + AQ and A L, respectively. The polymerase chain reaction-corrected adequate clinical and parasitological response was 100% and 98.07% at day 42 for AS + AQ and AL, respectively. Conclusion: Patients treated with AS + AQ and AL had cleared parasites rapidly. ACTs are still efficacious in Bouake, Cote d'Ivoire, but continued efficacy monitoring of ACTs is needed.

Published
2018

31. African leadership is critical in responding to public health threats

Author

Nicaise Ndembi, Aggrey Aluso, Mahlet K. Habtemariam, Landry Tsague, Gwen Mwaba, Abdu Muktar, Nafisa Jiwani, Krishna Udayakumar, Trevor A. Crowell, Alain Ngashi Ngongo, and Jean Kaseya

Subjects
Science
Abstract

The African continent demonstrated decisive leadership throughout its response to the COVID-19 pandemic, leveraging lessons learned from previous outbreaks and acting quickly to limit the impact of the SARS-CoV-2 virus. We propose a framework to build on these successes that calls for greater collaboration between African leaders, and greater inclusion of African voices in the global health ecosystem.

Published
2024
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40. Second Interim Report of the Working Group on Aquaculture (WGAQUA)

Author

Bannister, R. (Raymond), Bengtson, D. (David), Boyd, A. (Adele), Boxaspen, K. (Karin), Busby, C. (Corina), Callier, M. (Myriam), Cranford, P. (Peter), Cross, S. (Stephen), Djupevåg, E.M. (Else Marie), Flimlin, G. (Gef), Focken, U. (Ulfert), Gestal, C. (Camino), García-Tasende, M. (Manuel), González-Castro, C. (Carmen), Hareide, H. (Henrik), Iglesias-Estévez, J. (José), Jackson, D. (Dave), Kamermans, P. (Pauline), Knaus, U. (Ulrich), Landry, T. (Thomas), McKindsey, C. (Chris), Moberg, O. (Olav), Moore, H. (Heather), O’Beirn, F. (Francis), Simonsen, K. (Knud), Svåsand, T. (Terje), Strand, O. (Oivind), and ICES

Published
2014

45. An integrated ecosystem approach for assessing the potential role of cultivated bivalve shells as part of the carbon trading system

Author

Filgueira, Ramón, Byron, C.J., Comeau, L.A., Costa-Pierce, B., Cranford, Peter J., Ferreira, J.G., Grant, J., Guyondet, T., Jansen, H.M., Landry, T., McKindsey, C.W., Petersen, Jens Kjerulf, Reid, G.K., Robinson, S.M.C., Small, A., Sonier, R., Strand, Ø., Strohmeier, T., Filgueira, Ramón, Byron, C.J., Comeau, L.A., Costa-Pierce, B., Cranford, Peter J., Ferreira, J.G., Grant, J., Guyondet, T., Jansen, H.M., Landry, T., McKindsey, C.W., Petersen, Jens Kjerulf, Reid, G.K., Robinson, S.M.C., Small, A., Sonier, R., Strand, Ø., and Strohmeier, T.

Abstract

The role of bivalve mariculture in the CO2 cycle has been commonly evaluated as the balance between respiration, shell calcium carbonate sequestration and CO2 release during biogenic calcification. However, this approach neglects the ecosystem implications of cultivating bivalves at high densities, e.g. the impact on phytoplankton dynamics and benthic-pelagic coupling, which can significantly contribute to the CO2 cycle. Therefore, an ecosystem approach that accounts for the trophic interactions of bivalve aquaculture, including dissolved and particulate organic and inorganic carbon cycling, is needed to provide a rigorous assessment of the role of bivalve mariculture in the CO2 cycle. On the other hand, the discussion about the inclusion of shells of cultured bivalves into the carbon trading system should be framed in the context of ecosystem goods and services. Humans culture bivalves with the aim of producing food, not sequestering CO2 in their shells, therefore the main ecosystem good provided by bivalve aquaculture is meat production, and shells should be considered as by-products of this human activity. This reasoning is key to split the CO2 released due to respiration between meat and shell when constructing a specific CO2 budget for shells for evaluating the potential of including bivalve shells, and not the whole organism, in the carbon trading system. Concluding, an integrated ecosystem approach as well as an understanding of the ecosystems goods and services of bivalve aquaculture are two essential requisites for providing a reliable assessment of the role of bivalve shells in the CO2 cycle

Published
2015

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