Search

Your search keyword '"Landau S"' showing total 1,096 results
Start Over Author "Landau S"
1,096 results on '"Landau S"'

2. Constraining a possible time-variation of the speed of light along with the fine-structure constant using strong gravitational lensing and Type Ia supernovae observations

Author

Colaço, L. R., Landau, S. J., Gonzalez, J. E., Spinelly, J., and Santos, G. L. F.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The possible time variation of the fundamental constants of nature has been an active subject of research since the large-number hypothesis was proposed by Dirac. In this paper, we propose a new method to investigate a possible time variation of the speed of light ($c$) along with the fine-structure constant ($\alpha$) using Strong Gravitational Lensing (SGL) and Type Ia Supernovae (SNe Ia) observations. We assume a general approach to describe the mass distribution of lens-type galaxies, the one in favor of the power-law index model (PLAW). We also consider the runaway dilaton model to describe a possible time-variation of $\alpha$. In order to explore the results deeply, we split the SGL sample into five sub-samples according to the lens stellar velocity dispersion and three sub-samples according to lens redshift. The results suggest that it is reasonable to treat the systems separately, but no strong indication of varying $c$ was found., Comment: 10 Pages, 4 Figures, and 1 Table. Published in JCAP

Published
2022
Full Text
View/download PDF

3. The Polygenic Risk Score Knowledge Base offers a centralized online repository for calculating and contextualizing polygenic risk scores

Author

Weiner, MW, Aisen, P, Petersen, R, Jack, CR, Jagust, W, Trojanowki, JQ, Toga, AW, Beckett, L, Green, RC, Saykin, AJ, Morris, JC, Perrin, RJ, Shaw, LM, Khachaturian, Z, Carrillo, M, Potter, W, Barnes, L, Bernard, M, González, H, Ho, C, Hsiao, JK, Jackson, J, Masliah, E, Masterman, D, Okonkwo, O, Perrin, R, Ryan, L, Silverberg, N, Fleisher, A, Sacrey, DT, Fockler, J, Conti, C, Veitch, D, Neuhaus, J, Jin, C, Nosheny, R, Ashford, M, Flenniken, D, Kormos, A, Monine, T, Rafii, M, Raman, R, Jimenez, G, Donohue, M, Gessert, D, Salazar, J, Zimmerman, C, Cabrera, Y, Walter, S, Miller, G, Coker, G, Clanton, T, Hergesheimer, L, Smith, S, Adegoke, O, Mahboubi, P, Moore, S, Pizzola, J, Shaffer, E, Sloan, B, Harvey, D, Forghanian-Arani, A, Borowski, B, Ward, C, Schwarz, C, Jones, D, Gunter, J, Kantarci, K, Senjem, M, Vemuri, P, Reid, R, Fox, NC, Malone, I, Thompson, P, Thomopoulos, SI, Nir, TM, Jahanshad, N, DeCarli, C, Knaack, A, Fletcher, E, Tosun-Turgut, D, Chen, SR, Choe, M, Crawford, K, Yushkevich, PA, Das, S, Koeppe, RA, Reiman, EM, Chen, K, Mathis, C, Landau, S, Cairns, NJ, Householder, E, Franklin, E, Bernhardt, H, Taylor-Reinwald, L, Tojanowki, JQ, Korecka, M, and Figurski, M

Subjects
Biological Sciences, Genetics, Prevention, Human Genome, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Knowledge Bases, Multifactorial Inheritance, Polymorphism, Single Nucleotide, Risk Factors, Alzheimer’s Disease Neuroimaging Initiative, Biological sciences, Biomedical and clinical sciences
Abstract

The process of identifying suitable genome-wide association (GWA) studies and formatting the data to calculate multiple polygenic risk scores on a single genome can be laborious. Here, we present a centralized polygenic risk score calculator currently containing over 250,000 genetic variant associations from the NHGRI-EBI GWAS Catalog for users to easily calculate sample-specific polygenic risk scores with comparable results to other available tools. Polygenic risk scores are calculated either online through the Polygenic Risk Score Knowledge Base (PRSKB; https://prs.byu.edu ) or via a command-line interface. We report study-specific polygenic risk scores across the UK Biobank, 1000 Genomes, and the Alzheimer's Disease Neuroimaging Initiative (ADNI), contextualize computed scores, and identify potentially confounding genetic risk factors in ADNI. We introduce a streamlined analysis tool and web interface to calculate and contextualize polygenic risk scores across various studies, which we anticipate will facilitate a wider adaptation of polygenic risk scores in future disease research.

Published
2022

5. QUBIC II: Spectro-Polarimetry with Bolometric Interferometry

Author

Mousset, L., Lerena, M. M. Gamboa, Battistelli, E. S., de Bernardis, P., Chanial, P., D'Alessandro, G., Dashyan, G., De Petris, M., Grandsire, L., Hamilton, J. -Ch., Incardona, F., Landau, S., Marnieros, S., Masi, S., Mennella, A., O'Sullivan, C., Piat, M., Ricciardi, G., Scóccola, C. G., Stolpovskiy, M., Tartari, A., Thermeau, J. -P., Torchinsky, S. A., Voisin, F., Zannoni, M., Ade, P., Alberro, J. G., Almela, A., Amico, G., Arnaldi, L. H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Bélier, B., Baù, A., Bennett, D., Bergé, L., Bernard, J. -Ph., Bersanelli, M., Bigot-Sazy, M. -A., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chapron, C., Charlassier, R., Cerutti, A. C. Cobos, Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L. P., Fracchia, D., Franceschet, C., Ganga, K. M., García, B., Redondo, M. E. García, Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., Berisso, M. Gómez, González, M., Gradziel, M., Hampel, M. R., Harari, D., Henrot-Versillé, S., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Marty, W., Mattei, A., May, A., McCulloch, M., Mele, L., Melo, D., Montier, L., Mundo, L. M., Murphy, J. A., Murphy, J. D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G. E., Salum, J. M., Schillaci, A., Scully, S., Spinelli, S., Stankowiak, G., Supanitsky, A. D., Timbie, P., Tomasi, M., Tucker, G., Tucker, C., Viganò, D., Vittorio, N., Wicek, F., Wright, M., and Zullo, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Bolometric interferometry is a novel technique that has the ability to perform spectral imaging. A bolometric interferometer observes the sky in a wide frequency band and can reconstruct sky maps in several sub-bands within the physical band in post-processing of the data. This provides a powerful spectral method to discriminate between the cosmic microwave background (CMB) and astrophysical foregrounds. In this paper, the methodology is illustrated with examples based on the Q \& U Bolometric Interferometer for Cosmology (QUBIC) which is a ground-based instrument designed to measure the B-mode polarization of the sky at millimeter wavelengths. We consider the specific cases of point source reconstruction and Galactic dust mapping and we characterize the point spread function as a function of frequency. We study the noise properties of spectral imaging, especially the correlations between sub-bands, using end-to-end simulations together with a fast noise simulator. We conclude showing that spectral imaging performance are nearly optimal up to five sub-bands in the case of QUBIC., Comment: 27 pages, 18 figures. Accepted by JCAP on July 6, 2021. Second paper of series of 8 in a special JCAP edition on QUBIC

Published
2020
Full Text
View/download PDF

7. Galaxy clusters, type Ia supernovae and the fine structure constant

Author

Holanda, R. F. L., Busti, V. C., Colaço, L. R., Alcaniz, J. S., and Landau, S. J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

As is well known, measurements of the Sunyaev-Zeldovich effect can be combined with observations of the X-ray surface brightness of galaxy clusters to estimate the angular diameter distance to these structures. In this paper, we show that this technique depends on the fine structure constant, $\alpha$. Therefore, if $\alpha$ is a time-dependent quantity, e.g., $\alpha=\alpha_0 \phi(z)$, where $\phi$ is a function of redshift, we argue that current data do not provide the real angular diameter distance, $D_{\rm{A}}(z)$, to the cluster but instead $D_A^{data}(z) = \phi(z)^2 D_{\rm{A}}(z)$. We use this result to derive constraints on a possible variation of $\alpha$ for a class of dilaton runaway models considering a sample of 25 measurements of $D_A^{data}(z)$ in redshift range $0.023 < z < 0.784$ and estimates of $D_{\rm{A}}(z)$ from current type Ia supernovae observations. We find no significant indication of variation of $\alpha$ with the present data., Comment: 8 pages, 4 figures, To appear in JCAP

Published
2016
Full Text
View/download PDF

8. Constraints on a possible variation of the fine structure constant from galaxy cluster data

Author

Holanda, R. F. L., Landau, S. J., Alcaniz, J. S., G., I. E. Sanchez, and Busti, V. C.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, General Relativity and Quantum Cosmology
Abstract

We propose a new method to probe a possible time evolution of the fine structure constant $\alpha$ from X-ray and Sunyaev-Zeldovich measurements of the gas mass fraction ($f_{gas}$) in galaxy clusters. Taking into account a direct relation between variations of $\alpha$ and violations of the distance-duality relation, we discuss constraints on $\alpha$ for a class of dilaton runaway models. Although not yet competitive with bounds from high-$z$ quasar absorption systems, our constraints, considering a sample of 29 measurements of $f_{gas}$, in the redshift interval $0.14 < z < 0.89$, provide an independent estimate of $\alpha$ variation at low and intermediate redshifts. Furthermore, current and planned surveys will provide a larger amount of data and thus allow to improve the limits on $\alpha$ variation obtained in the present analysis., Comment: 7 pages, 2 figures, accepted for publication in JCAP

Published
2015
Full Text
View/download PDF

9. How does cognitive behavior therapy for dissociative seizures work? A mediation analysis of the CODES trial.

Author

Chalder, T., Landau, S., Stone, J., Carson, A., Reuber, M., Medford, N., Robinson, E. J., and Goldstein, L. H.

Subjects
*PSYCHOGENIC nonepileptic seizures, *RESEARCH funding, *SECONDARY analysis, *QUESTIONNAIRES, *TREATMENT effectiveness, *DESCRIPTIVE statistics, *COGNITIVE therapy, *FACTOR analysis, *DATA analysis software, *BEHAVIOR therapy
Abstract

Background: We compared dissociative seizure specific cognitive behavior therapy (DS-CBT) plus standardized medical care (SMC) to SMC alone in a randomized controlled trial. DS-CBT resulted in better outcomes on several secondary trial outcome measures at the 12-month follow-up point. The purpose of this paper is to evaluate putative treatment mechanisms. Methods: We carried out a secondary mediation analysis of the CODES trial. 368 participants were recruited from the National Health Service in secondary / tertiary care in England, Scotland, and Wales. Sixteen mediation hypotheses corresponding to combinations of important trial outcomes and putative mediators were assessed. Twelve-month trial outcomes considered were final-month seizure frequency, Work and Social Adjustment Scale (WSAS), and the SF-12v2, a quality-of-life measure providing physical (PCS) and mental component summary (MCS) scores. Mediators chosen for analysis at six months (broadly corresponding to completion of DS-CBT) included: (a) beliefs about emotions, (b) a measure of avoidance behavior, (c) anxiety and (d) depression. Results: All putative mediator variables except beliefs about emotions were found to be improved by DS-CBT. We found evidence for DS-CBT effect mediation for the outcome variables dissociative seizures (DS), WSAS and SF-12v2 MCS scores by improvements in target variables avoidance behavior, anxiety, and depression. The only variable to mediate the DS-CBT effect on the SF-12v2 PCS score was avoidance behavior. Conclusions: Our findings largely confirmed the logic model underlying the development of CBT for patients with DS. Interventions could be additionally developed to specifically address beliefs about emotions to assess whether it improves outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

10. On Inflation and Variation of the Strong Coupling Constant

Author

Chamoun, N., Landau, S. J., and Vucetich, H.

Subjects
Astrophysics, General Relativity and Quantum Cosmology, High Energy Physics - Phenomenology
Abstract

Variation of constants in the very early universe can generate inflation. We consider a scenario where the strong coupling constant was changing in time and where the gluon condensate underwent a phase transition ending the inflation., Comment: 12 pages, 1 figure, accepted for publication in International Journal of Modern Physics D

Published
2006
Full Text
View/download PDF

12. A Time Varying Strong Coupling Constant as a Model of Inflationary Universe

Author

Chamoun, N., Landau, S. J., and Vucetich, H.

Subjects
Astrophysics, General Relativity and Quantum Cosmology
Abstract

We consider a scenario where the strong coupling constant was changing in the early universe. We attribute this change to a variation in the colour charge within a Bekenstein-like model. Treating the vacuum gluon condensate $$ as a free paramete r, we could generate inflation with the required properties to solve the fluctuation and other standard cosmology problems. A possible approach to end the inflation is suggested., Comment: 11 pages

Published
2000

13. Bekenstein model and the time variation of the strong coupling constant

Author

Chamoun, N., Landau, S. J., and Vucetich, H.

Subjects
Astrophysics, High Energy Physics - Phenomenology
Abstract

We propose to generalize Bekenstein model for the time variation of the fine structure "constant" $\alpha_{em}$ to QCD strong coupling constant $\alpha_S$. We find that, except for a ``fine tuned'' choice of the free parameters, the extension can not be performed trivially without being in conflict with experimental constraints and this rules out $\alpha_S$ variability. This is due largely to the huge numerical value of the QCD vacuum gluon condensate when compared to the matter density of the universe., Comment: 8 pages.typos corrected

Published
2000
Full Text
View/download PDF

16. QUBIC II: Spectral polarimetry with bolometric interferometry

Author

Mousset, L, Gamboa Lerena, M, Battistelli, E, de Bernardis, P, Chanial, P, D'Alessandro, G, Dashyan, G, De Petris, M, Grandsire, L, Hamilton, J, Incardona, F, Landau, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M, Ricciardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Thermeau, J, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot-Sazy, M, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Charlassier, R, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, M, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, González, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Jules, E, Kaplan, J, Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Mandelli, S, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Rasztocky, E, Ringegni, P, Romero, G, Salum, J, Schillaci, A, Scully, S, Spinelli, S, Stankowiak, G, Supanitsky, A, Timbie, P, Tomasi, M, Tucker, C, Tucker, G, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Mousset, L., Gamboa Lerena, M. M., Battistelli, E. S., de Bernardis, P., Chanial, P., D'Alessandro, G., Dashyan, G., De Petris, M., Grandsire, L., Hamilton, J. -Ch., Incardona, F., Landau, S., Marnieros, S., Masi, S., Mennella, A., O'Sullivan, C., Piat, M., Ricciardi, G., Scóccola, C. G., Stolpovskiy, M., Tartari, A., Thermeau, J. -P., Torchinsky, S. A., Voisin, F., Zannoni, M., Ade, P., Alberro, J. G., Almela, A., Amico, G., Arnaldi, L. H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J. -Ph., Bersanelli, M., Bigot-Sazy, M. -A., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chapron, C., Charlassier, R., Cobos Cerutti, A. C., Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L. P., Fracchia, D., Franceschet, C., Ganga, K. M., García, B., García Redondo, M. E., Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., Gómez Berisso, M., González, M., Gradziel, M., Hampel, M. R., Harari, D., Henrot-Versillé, S., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Mandelli, S., Marty, W., Mattei, A., May, A., McCulloch, M., Mele, L., Melo, D., Montier, L., Mundo, L. M., Murphy, J. A., Murphy, J. D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G. E., Salum, J. M., Schillaci, A., Scully, S., Spinelli, S., Stankowiak, G., Supanitsky, A. D., Timbie, P., Tomasi, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Wicek, F., Wright, M., Zullo, A., Mousset, L, Gamboa Lerena, M, Battistelli, E, de Bernardis, P, Chanial, P, D'Alessandro, G, Dashyan, G, De Petris, M, Grandsire, L, Hamilton, J, Incardona, F, Landau, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M, Ricciardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Thermeau, J, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot-Sazy, M, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Charlassier, R, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, M, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, González, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Jules, E, Kaplan, J, Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Mandelli, S, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Rasztocky, E, Ringegni, P, Romero, G, Salum, J, Schillaci, A, Scully, S, Spinelli, S, Stankowiak, G, Supanitsky, A, Timbie, P, Tomasi, M, Tucker, C, Tucker, G, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Mousset, L., Gamboa Lerena, M. M., Battistelli, E. S., de Bernardis, P., Chanial, P., D'Alessandro, G., Dashyan, G., De Petris, M., Grandsire, L., Hamilton, J. -Ch., Incardona, F., Landau, S., Marnieros, S., Masi, S., Mennella, A., O'Sullivan, C., Piat, M., Ricciardi, G., Scóccola, C. G., Stolpovskiy, M., Tartari, A., Thermeau, J. -P., Torchinsky, S. A., Voisin, F., Zannoni, M., Ade, P., Alberro, J. G., Almela, A., Amico, G., Arnaldi, L. H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J. -Ph., Bersanelli, M., Bigot-Sazy, M. -A., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chapron, C., Charlassier, R., Cobos Cerutti, A. C., Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L. P., Fracchia, D., Franceschet, C., Ganga, K. M., García, B., García Redondo, M. E., Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., Gómez Berisso, M., González, M., Gradziel, M., Hampel, M. R., Harari, D., Henrot-Versillé, S., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Mandelli, S., Marty, W., Mattei, A., May, A., McCulloch, M., Mele, L., Melo, D., Montier, L., Mundo, L. M., Murphy, J. A., Murphy, J. D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G. E., Salum, J. M., Schillaci, A., Scully, S., Spinelli, S., Stankowiak, G., Supanitsky, A. D., Timbie, P., Tomasi, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Wicek, F., Wright, M., and Zullo, A.

Abstract

Bolometric interferometry is a novel technique that has the ability to perform spectral imaging. A bolometric interferometer observes the sky in a wide frequency band and can reconstruct sky maps in several sub-bands within the physical band in post-processing of the data. This provides a powerful spectral method to discriminate between the cosmic microwave background (CMB) and astrophysical foregrounds. In this paper, the methodology is illustrated with examples based on the Q & U Bolometric Interferometer for Cosmology (QUBIC) which is a ground-based instrument designed to measure the B-mode polarization of the sky at millimeter wavelengths. We consider the specific cases of point source reconstruction and Galactic dust mapping and we characterize the point spread function as a function of frequency. We study the noise properties of spectral imaging, especially the correlations between sub-bands, using end-to-end simulations together with a fast noise simulator. We conclude showing that spectral imaging performance are nearly optimal up to five sub-bands in the case of QUBIC.

Published
2022

20. QUBIC II: Spectral polarimetry with bolometric interferometry

Author

Mousset, L., Gamboa Lerena, M.M., Battistelli, E.S., de Bernardis, P., Chanial, P., D'Alessandro, G., Dashyan, G., De Petris, M., Grandsire, L., Hamilton, J.-Ch., Incardona, F., Landau, S., Marnieros, S., Masi, S., Mennella, A., O'Sullivan, C., Piat, M., Ricciardi, G., Scóccola, C.G., Stolpovskiy, M., Tartari, A., Thermeau, J.-P., Torchinsky, S.A., Voisin, F., Zannoni, M., Ade, P., Alberro, J.G., Almela, A., Amico, G., Arnaldi, L.H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Baù, A., Bélier, B., Bennett, D., Bergé, L., Bernard, J.-Ph., Bersanelli, M., Bigot-Sazy, M.-A., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chapron, C., Charlassier, R., Cobos Cerutti, A.C., Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L.P., Fracchia, D., Franceschet, C., Ganga, K.M., García, B., García Redondo, M.E., Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., Gómez Berisso, M., González, M., Gradziel, M., Hampel, M.R., Harari, D., Henrot-Versillé, S., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Mandelli, S., Marty, W., Mattei, A., May, A., McCulloch, M., Mele, L., Melo, D., Montier, L., Mundo, L.M., Murphy, J.A., Murphy, J.D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Prêle, D., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G.E., Salum, J.M., Schillaci, A., Scully, S., Spinelli, S., Stankowiak, G., Supanitsky, A.D., Timbie, P., Tomasi, M., Tucker, C., Tucker, G., Viganò, D., Vittorio, N., Wicek, F., Wright, M., Zullo, A., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris - Site de Paris (OP), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Centre de Nanosciences et de Nanotechnologies [Orsay] (C2N), Université Paris-Sud - Paris 11 (UP11)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, QUBIC, Mousset, L, Gamboa Lerena, M, Battistelli, E, de Bernardis, P, Chanial, P, D'Alessandro, G, Dashyan, G, De Petris, M, Grandsire, L, Hamilton, J, Incardona, F, Landau, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M, Ricciardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Thermeau, J, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bigot-Sazy, M, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Charlassier, R, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, M, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, González, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Jules, E, Kaplan, J, Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Mandelli, S, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Rasztocky, E, Ringegni, P, Romero, G, Salum, J, Schillaci, A, Scully, S, Spinelli, S, Stankowiak, G, Supanitsky, A, Timbie, P, Tomasi, M, Tucker, C, Tucker, G, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), and Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Manchester Cancer Research Centre, ResearchInstitutes_Networks_Beacons/mcrc, Astrophysics::Instrumentation and Methods for Astrophysics, FOS: Physical sciences, cosmological parameters from CMBR, Astronomy and Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, CMBR theory, CMBR experiments, CMBR theory, cosmological parameters from CMBR, gravitational waves and CMBR polarization, FIS/05 - ASTRONOMIA E ASTROFISICA, FIS/01 - FISICA SPERIMENTALE, CMBR experiments, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], CMBR experiment, Astrophysics - Instrumentation and Methods for Astrophysics, gravitational waves and CMBR polarization, Instrumentation and Methods for Astrophysics (astro-ph.IM), Astrophysics::Galaxy Astrophysics
Abstract

Bolometric interferometry is a novel technique that has the ability to perform spectral imaging. A bolometric interferometer observes the sky in a wide frequency band and can reconstruct sky maps in several sub-bands within the physical band in post-processing of the data. This provides a powerful spectral method to discriminate between the cosmic microwave background (CMB) and astrophysical foregrounds. In this paper, the methodology is illustrated with examples based on the Q \& U Bolometric Interferometer for Cosmology (QUBIC) which is a ground-based instrument designed to measure the B-mode polarization of the sky at millimeter wavelengths. We consider the specific cases of point source reconstruction and Galactic dust mapping and we characterize the point spread function as a function of frequency. We study the noise properties of spectral imaging, especially the correlations between sub-bands, using end-to-end simulations together with a fast noise simulator. We conclude showing that spectral imaging performance are nearly optimal up to five sub-bands in the case of QUBIC., 27 pages, 18 figures. Accepted by JCAP on July 6, 2021. Second paper of series of 8 in a special JCAP edition on QUBIC

Published
2022

24. QUBIC I: Overview and ScienceProgram

Author

Hamilton, J. -Ch., Mousset, L., Battistelli, E. S., de Bernardis, P., Bigot-Sazy, M. -A., Chanial, P., Charlassier, R., D'Alessandro, G., De Petris, M., Gamboa Lerena, M. M., Grandsire, L., Landau, S., Mandelli, S., Marnieros, S., Masi, S., Mennella, A., O'Sullivan, C., Piat, M., Ricciardi, G., Sc??ccola, C. G., Stolpovskiy, M., Tartari, A., Torchinsky, S. A., Voisin, F., Zannoni, M., Ade, P., Alberro, J. G., Almela, A., Amico, G., Arnaldi, L. H., Auguste, D., Aumont, J., Azzoni, S., Banfi, S., Ba??, A., B??lier, B., Bennett, D., Berg??, L., Bernard, J. -Ph., Bersanelli, M., Bonaparte, J., Bonis, J., Bunn, E., Burke, D., Buzi, D., Cavaliere, F., Chapron, C., Cobos Cerutti, A. C., Columbro, F., Coppolecchia, A., De Gasperis, G., De Leo, M., Dheilly, S., Duca, C., Dumoulin, L., Etchegoyen, A., Fasciszewski, A., Ferreyro, L. P., Fracchia, D., Franceschet, C., Ganga, K. M., Garc??a, B., Redondo, M. E. Garc??a., Gaspard, M., Gayer, D., Gervasi, M., Giard, M., Gilles, V., Giraud-Heraud, Y., G??mez Berisso, M., Gonz??lez, M., Gradziel, M., Hampel, M. R., Harari, D., Henrot-Versill??, S., Incardona, F., Jules, E., Kaplan, J., Kristukat, C., Lamagna, L., Loucatos, S., Louis, T., Maffei, B., Marty, W., Mattei, A., May, A., Mcculloch, M., Mele, L., Melo, D., Montier, L., Mundo, L. M., Murphy, J. A., Murphy, J. D., Nati, F., Olivieri, E., Oriol, C., Paiella, A., Pajot, F., Passerini, A., Pastoriza, H., Pelosi, A., Perbost, C., Perciballi, M., Pezzotta, F., Piacentini, F., Piccirillo, L., Pisano, G., Platino, M., Polenta, G., Pr??le, D., Puddu, R., Rambaud, D., Rasztocky, E., Ringegni, P., Romero, G. E., Salum, J. M., Schillaci, A., Scully, S., Spinelli, S., Stankowiak, G., Supanitsky, A. D., Thermeau, J. -P., Timbie, P., Tomasi, M., Tucker, C., Tucker, G., Vigan??, D., Vittorio, N., Wicek, F., Wright, M., Zullo, A., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Observatoire de Paris - Site de Paris (OP), Centre National de la Recherche Scientifique (CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Centre de Nanosciences et de Nanotechnologies [Orsay] (C2N), Université Paris-Sud - Paris 11 (UP11)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), QUBIC, Hamilton, J, Mousset, L, Battistelli, E, de Bernardis, P, Bigot-Sazy, M, Chanial, P, Charlassier, R, D'Alessandro, G, De Petris, M, Gamboa Lerena, M, Grandsire, L, Landau, S, Mandelli, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M, Ricciardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Baù, A, Bélier, B, Bennett, D, Bergé, L, Bernard, J, Bersanelli, M, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, M, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, González, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Incardona, F, Jules, E, Kaplan, J, Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Rasztocky, E, Ringegni, P, Romero, G, Salum, J, Schillaci, A, Scully, S, Spinelli, S, Stankowiak, G, Supanitsky, A, Thermeau, J, Timbie, P, Tomasi, M, Tucker, C, Tucker, G, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), and Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES)

Subjects
cosmological model, data analysis method, Cosmology and Nongalactic Astrophysics (astro-ph.CO), satellite: Planck, interferometer, FOS: Physical sciences, cosmic background radiation: polarization, Astrophysics::Cosmology and Extragalactic Astrophysics, B-mode: primordial, statistical analysis, bolometer, CMBRexperiments, CMBR theory, cosmological parameters from CMBR, gravitational waves and CMBR polarization, CMBR experiments, detector: calibration, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], atmosphere: effect, numerical calculations, Instrumentation and Methods for Astrophysics (astro-ph.IM), Astrophysics::Galaxy Astrophysics, CMBRexperiments, polarization, beam: polarization, Settore FIS/05, Astrophysics::Instrumentation and Methods for Astrophysics, cosmological parameters from CMBR, Astronomy and Astrophysics, stability, CMBR theory, detector: sensitivity, B-mode, galaxy, CMBR experiment, Astrophysics - Instrumentation and Methods for Astrophysics, gravitational waves and CMBR polarization, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The Q $\&$ U Bolometric Interferometer for Cosmology (QUBIC) is a novel kind of polarimeter optimized for the measurement of the B-mode polarization of the Cosmic Microwave Background (CMB), which is one of the major challenges of observational cosmology. The signal is expected to be of the order of a few tens of nK, prone to instrumental systematic effects and polluted by various astrophysical foregrounds which can only be controlled through multichroic observations. QUBIC is designed to address these observational issues with a novel approach that combines the advantages of interferometry in terms of control of instrumental systematic effects with those of bolometric detectors in terms of wide-band, background-limited sensitivity. The QUBIC synthesized beam has a frequency-dependent shape that results in the ability to produce maps of the CMB polarization in multiple sub-bands within the two physical bands of the instrument (150 and 220 GHz). These features make QUBIC complementary to other instruments and makes it particularly well suited to characterize and remove Galactic foreground contamination. In this article, first of a series of eight, we give an overview of the QUBIC instrument design, the main results of the calibration campaign, and present the scientific program of QUBIC including not only the measurement of primordial B-modes, but also the measurement of Galactic foregrounds. We give forecasts for typical observations and measurements: with three years of integration on the sky and assuming perfect foreground removal as well as stable atmospheric conditions from our site in Argentina, our simulations show that we can achieve a statistical sensitivity to the effective tensor-to-scalar ratio (including primordial and foreground B-modes) $\sigma(r)=0.015$., Comment: 34 pages, 16 figures, accepted for publication by JCAP. Overview paper for a series of 8 QUBIC articles special JCAP edition dedicated to QUBIC

Published
2021

25. The feasibility of delivering the ADVANCE digital intervention to reduce intimate partner abuse by men receiving substance use treatment: protocol for a non-randomised multi-centre feasibility study and embedded process evaluation

Author

Gilchrist, G, Landau, S, Dheensa, S, Henderson, J, Johnson, A, Love, B, Potts, L, Radcliffe, P, Zenasni, Z, Parrott, S, Li, J, Thomson, K, Dwyer, G-J, Turner, R, Halliwell, G, Berbary, C, Bergman, C, Feder, G, Easton, C, Brooks, CP, Gilchrist, E, Gilchrist, G, Landau, S, Dheensa, S, Henderson, J, Johnson, A, Love, B, Potts, L, Radcliffe, P, Zenasni, Z, Parrott, S, Li, J, Thomson, K, Dwyer, G-J, Turner, R, Halliwell, G, Berbary, C, Bergman, C, Feder, G, Easton, C, Brooks, CP, and Gilchrist, E

Abstract

BACKGROUND: Compared to men in the general population, men in substance use treatment are more likely to perpetrate intimate partner abuse (IPA). The ADVANCE group intervention for men in substance use treatment is tailored to address substance use and IPA in an integrated way. In a feasibility trial pre-COVID, men who received the ADVANCE intervention via face-to-face group delivery showed reductions in IPA perpetration. Due to COVID-19, ADVANCE was adapted for remote digital delivery. METHODS/DESIGN: This mixed-methods non-randomised feasibility study, with a nested process evaluation, will explore the feasibility and acceptability of delivering the ADVANCE digital intervention to men in substance use treatment who have perpetrated IPA towards a female partner in the past year. Sixty men will be recruited from seven substance use treatment services in Great Britain. The ADVANCE digital intervention comprises a preparatory one-to-one session with a facilitator to set goals, develop a personal safety plan, and increase motivation and a preparatory online group to prepare men for taking part in the intervention. The core intervention comprises six fortnightly online group sessions and 12 weekly self-directed website sessions to recap and practise skills learned in the online group sessions. Each website session is followed by a one-to-one video/phone coaching session with a facilitator. Men will also receive their usual substance use treatment. Men's female (ex) partners will be invited to provide outcome data and offered support from integrated safety services (ISS). Outcome measures for men and women will be sought post intervention (approximately 4 months post male baseline interview). Feasibility parameters to be estimated include eligibility, suitability, consent, recruitment, attendance, retention and follow-up rates. In-depth interviews or focus groups will explore the intervention's acceptability to participants, facilitators and ISS workers. A secondary focu

Published
2022

28. QUBIC I: Overview and science program

Author

Hamilton, J.-Ch., additional, Mousset, L., additional, Battistelli, E.S., additional, de Bernardis, P., additional, Bigot-Sazy, M.-A., additional, Chanial, P., additional, Charlassier, R., additional, D'Alessandro, G., additional, De Petris, M., additional, Gamboa Lerena, M.M., additional, Grandsire, L., additional, Landau, S., additional, Mandelli, S., additional, Marnieros, S., additional, Masi, S., additional, Mennella, A., additional, O'Sullivan, C., additional, Piat, M., additional, Ricciardi, G., additional, Scóccola, C.G., additional, Stolpovskiy, M., additional, Tartari, A., additional, Torchinsky, S.A., additional, Voisin, F., additional, Zannoni, M., additional, Ade, P., additional, Alberro, J.G., additional, Almela, A., additional, Amico, G., additional, Arnaldi, L.H., additional, Auguste, D., additional, Aumont, J., additional, Azzoni, S., additional, Banfi, S., additional, Baù, A., additional, Bélier, B., additional, Bennett, D., additional, Bergé, L., additional, Bernard, J.-Ph., additional, Bersanelli, M., additional, Bonaparte, J., additional, Bonis, J., additional, Bunn, E., additional, Burke, D., additional, Buzi, D., additional, Cavaliere, F., additional, Chapron, C., additional, Cobos Cerutti, A.C., additional, Columbro, F., additional, Coppolecchia, A., additional, De Gasperis, G., additional, De Leo, M., additional, Dheilly, S., additional, Duca, C., additional, Dumoulin, L., additional, Etchegoyen, A., additional, Fasciszewski, A., additional, Ferreyro, L.P., additional, Fracchia, D., additional, Franceschet, C., additional, Ganga, K.M., additional, García, B., additional, García Redondo, M.E., additional, Gaspard, M., additional, Gayer, D., additional, Gervasi, M., additional, Giard, M., additional, Gilles, V., additional, Giraud-Heraud, Y., additional, Gómez Berisso, M., additional, González, M., additional, Gradziel, M., additional, Hampel, M.R., additional, Harari, D., additional, Henrot-Versillé, S., additional, Incardona, F., additional, Jules, E., additional, Kaplan, J., additional, Kristukat, C., additional, Lamagna, L., additional, Loucatos, S., additional, Louis, T., additional, Maffei, B., additional, Marty, W., additional, Mattei, A., additional, May, A., additional, McCulloch, M., additional, Mele, L., additional, Melo, D., additional, Montier, L., additional, Mundo, L.M., additional, Murphy, J.A., additional, Murphy, J.D., additional, Nati, F., additional, Olivieri, E., additional, Oriol, C., additional, Paiella, A., additional, Pajot, F., additional, Passerini, A., additional, Pastoriza, H., additional, Pelosi, A., additional, Perbost, C., additional, Perciballi, M., additional, Pezzotta, F., additional, Piacentini, F., additional, Piccirillo, L., additional, Pisano, G., additional, Platino, M., additional, Polenta, G., additional, Prêle, D., additional, Puddu, R., additional, Rambaud, D., additional, Rasztocky, E., additional, Ringegni, P., additional, Romero, G.E., additional, Salum, J.M., additional, Schillaci, A., additional, Scully, S., additional, Spinelli, S., additional, Stankowiak, G., additional, Supanitsky, A.D., additional, Thermeau, J.-P., additional, Timbie, P., additional, Tomasi, M., additional, Tucker, C., additional, Tucker, G., additional, Viganò, D., additional, Vittorio, N., additional, Wicek, F., additional, Wright, M., additional, and Zullo, A., additional

Published
2022
Full Text
View/download PDF

36. Finding the spiritual in the secular: a meta-analysis of changes in spirituality following secular mindfulness-based programs

Author

Landau, S. D. and Jones, F. W.

Subjects
Spirituality, Secular, MPBs, Mindfulness, Secularity
Abstract

Objectives: Spirituality has historically been a neglected aspect of people’s lives within a healthcare context. Previous meta-analyses of the effect of mindfulness-based programs (MBPs) on spirituality have been limited by the small number of includable studies that were available at the time, by not comparing MBPs to active controls, and by not investigating whether effects continue to be observed at follow-up. Therefore, the current systematic review and meta-analysis aimed to more comprehensively examine whether, and to what extent, secular MBPs increase spirituality, and to identify moderators of any observed effects. Methods: Random effects meta-analyses were conducted on 13 controlled trials of MBPs measuring spirituality that were identified by a systematic search of PsycInfo and Medline. Results: At post-intervention, MBPs increased spirituality compared to both passive and active controls (passive: g = 0.52, 95% C.I.: 0.35 to 0.68; active: g = 0.34, 95% C.I.: 0.14 to 0.54), and effects continued to be observed at follow-up (passive: g = 0.32, 95% C.I.: 0.09 to 0.55; active: g = 0.44, 95% C.I.: 0.18 to 0.71). For passive controls at post-intervention, cancer samples showed a significantly larger pooled effect than the non-cancer ones (cancer: g = 0.75, 95% C.I.: 0.52 to 0.98; non-cancer: g = 0.38, 95% C.I.: 0.20 to 0.56; χ2(1) = 6.14, p = .01), but moderation analysis was not possible at follow-up or for active controls. Study quality was not significantly associated with effect size. Conclusions: Secular MBPs appear to increase spirituality, these effects endure beyond the end of the MBP and they cannot wholly be attributed to non-specific therapeutic factors. Limitations are discussed.

Published
2021

37. Impact on mental health care and on mental health service users of the COVID-19 pandemic:a mixed methods survey of UK mental health care staff

Author

Johnson, S., Dalton-Locke, C., Vera San Juan, N., Foye, U., Oram, S., Papamichail, A., Landau, S., Rowan Olive, R., Jeynes, T., Shah, P., Sheridan Rains, L., Lloyd-Evans, B., Carr, S., Killaspy, H., Gillard, S., Simpson, A., Bell, A., Bentivegna, F., Botham, J., Edbrooke-Childs, J., Goldsmith, L., Grunwald, L., Harju-Seppanen, J., Hatch, S., Henderson, C., Howrad, L., Lane, R., Ledden, S., Leveron, M., Lomani, J., Lyons, N., McCrone, P., Ntephe, C. U., Ocloo, J. E., Osborn, D., Pilling, S., Poursanidou, K., Scott, H. R., Steare, T., Stuart, R., Tomlin, A., Turner, K., and Tzouvara, V.

Subjects
Mental Health Services, Health (social science), Social Psychology, Epidemiology, BF, Qualitative property, RT, Health(social science), 03 medical and health sciences, 0302 clinical medicine, Nursing, Pandemic, medicine, Humans, Social media, 030212 general & internal medicine, Pandemics, Original Paper, Descriptive statistics, SARS-CoV-2, Social distance, COVID-19, Loneliness, Mental health care, Mental health staff, United Kingdom, 030227 psychiatry, Coronavirus, Psychiatry and Mental health, Mental Health, Mental health services, RC0321, Domestic violence, Professional association, medicine.symptom, Psychology, RA
Abstract

Purpose The COVID-19 pandemic has potential to disrupt and burden the mental health care system, and to magnify inequalities experienced by mental health service users. Methods We investigated staff reports regarding the impact of the COVID-19 pandemic in its early weeks on mental health care and mental health service users in the UK using a mixed methods online survey. Recruitment channels included professional associations and networks, charities, and social media. Quantitative findings were reported with descriptive statistics, and content analysis conducted for qualitative data. Results 2,180 staff from a range of sectors, professions, and specialties participated. Immediate infection control concerns were highly salient for inpatient staff, new ways of working for community staff. Multiple rapid adaptations and innovations in response to the crisis were described, especially remote working. This was cautiously welcomed but found successful in only some clinical situations. Staff had specific concerns about many groups of service users, including people whose conditions are exacerbated by pandemic anxieties and social disruptions; people experiencing loneliness, domestic abuse and family conflict; those unable to understand and follow social distancing requirements; and those who cannot engage with remote care. Conclusion This overview of staff concerns and experiences in the early COVID-19 pandemic suggests directions for further research and service development: we suggest that how to combine infection control and a therapeutic environment in hospital, and how to achieve effective and targeted tele-health implementation in the community, should be priorities. The limitations of our convenience sample must be noted.

Published
2021

38. Impact on mental health care and on mental health service users of the COVID-19 pandemic: a mixed methods survey of UK mental health care staff

Author

Johnson, S, Dalton-Locke, C, Vera San Juan, N, Foye, U, Oram, S, Papamichail, A, Landau, S, Rowan Olive, R, Jeynes, T, Shah, P, Sheridan Rains, L, Lloyd-Evans, B, Carr, S, Killaspy, H, Gillard, S, Simpson, A, and COVID-19 Mental Health Policy Research Unit Group

Abstract

PURPOSE: The COVID-19 pandemic has potential to disrupt and burden the mental health care system, and to magnify inequalities experienced by mental health service users. METHODS: We investigated staff reports regarding the impact of the COVID-19 pandemic in its early weeks on mental health care and mental health service users in the UK using a mixed methods online survey. Recruitment channels included professional associations and networks, charities, and social media. Quantitative findings were reported with descriptive statistics, and content analysis conducted for qualitative data. RESULTS: 2,180 staff from a range of sectors, professions, and specialties participated. Immediate infection control concerns were highly salient for inpatient staff, new ways of working for community staff. Multiple rapid adaptations and innovations in response to the crisis were described, especially remote working. This was cautiously welcomed but found successful in only some clinical situations. Staff had specific concerns about many groups of service users, including people whose conditions are exacerbated by pandemic anxieties and social disruptions; people experiencing loneliness, domestic abuse and family conflict; those unable to understand and follow social distancing requirements; and those who cannot engage with remote care. CONCLUSION: This overview of staff concerns and experiences in the early COVID-19 pandemic suggests directions for further research and service development: we suggest that how to combine infection control and a therapeutic environment in hospital, and how to achieve effective and targeted tele-health implementation in the community, should be priorities. The limitations of our convenience sample must be noted.

Published
2021

39. Effect of Vitamin D Supplementation on Outcomes in People with Early Psychosis: The DFEND Randomized Clinical Trial

Author

Gaughran, F, Stringer, D, Wojewodka, G, Landau, S, Smith, S, Gardner-Sood, P, Taylor, D, Jordan, H, Whiskey, E, Krivoy, A, Ciufolini, S, Stubbs, B, Casetta, C, Williams, J, Moore, S, Allen, L, Rathod, S, Boardman, A, Khalifa, R, Firdosi, M, McGuire, P, Berk, Michael, McGrath, J, Gaughran, F, Stringer, D, Wojewodka, G, Landau, S, Smith, S, Gardner-Sood, P, Taylor, D, Jordan, H, Whiskey, E, Krivoy, A, Ciufolini, S, Stubbs, B, Casetta, C, Williams, J, Moore, S, Allen, L, Rathod, S, Boardman, A, Khalifa, R, Firdosi, M, McGuire, P, Berk, Michael, and McGrath, J

Published
2021

40. ADVANCE integrated group intervention to address both substance use and intimate partner abuse perpetration by men in substance use treatment: a feasibility randomised controlled trial

Author

Gilchrist, G, Potts, L, Radcliffe, P, Halliwell, G, Dheensa, S, Henderson, J, Johnson, A, Love, B, Gilchrist, E, Feder, G, Parrott, S, Li, J, McMurran, M, Kirkpatrick, S, Stephens-Lewis, D, Easton, C, Berbary, C, Landau, S, Gilchrist, G, Potts, L, Radcliffe, P, Halliwell, G, Dheensa, S, Henderson, J, Johnson, A, Love, B, Gilchrist, E, Feder, G, Parrott, S, Li, J, McMurran, M, Kirkpatrick, S, Stephens-Lewis, D, Easton, C, Berbary, C, and Landau, S

Abstract

BACKGROUND: Substance use is a risk factor for intimate partner abuse (IPA) perpetration. Delivering perpetrator interventions concurrently with substance use treatment shows promise. METHODS: The feasibility of conducting an efficacy and cost-effectiveness trial of the ADVANCE 16-week intervention to reduce IPA by men in substance use treatment was explored. A multicentre, parallel group individually randomised controlled feasibility trial and formative evaluation was conducted. Over three temporal cycles, 104 men who had perpetrated IPA towards a female (ex) partner in the past year were randomly allocated to receive the ADVANCE intervention + substance use treatment as usual (TAU) (n = 54) or TAU only (n = 50) and assessed 16-weeks post-randomisation. Participants' (ex) partners were offered support and 27 provided outcome data. Thirty-one staff and 12 men who attended the intervention participated in focus groups or interviews that were analysed using the framework approach. Pre-specified criteria assessed the feasibility of progression to a definitive trial: 1) ≥ 60% of eligible male participants recruited; 2) intervention acceptable to staff and male participants; 3) ≥ 70% of participants followed-up and 4) levels of substance use and 5) IPA perpetrated by men in the intervention arm did not increase from average baseline level at 16-weeks post-randomisation. RESULTS: 70.7% (104/147) of eligible men were recruited. The formative evaluation confirmed the intervention's acceptability. Therapeutic alliance and session satisfaction were rated highly. The overall median rate of intervention session attendance (of 14 compulsory sessions) was 28.6% (range 14.3-64.3% by the third cycle). 49.0% (51/104) of men and 63.0% (17/27) of their (ex) partners were followed-up 16-weeks post-randomisation. This increased to 100% of men and women by cycle three. At follow-up, neither substance use nor IPA perpetration had worsened for men in the intervention arm. CONCLUSIONS: It w

Published
2021

41. QUBIC II: Spectro-Polarimetry with Bolometric Interferometry

Author

Mousset, L, Gamboa Lerena, M, Battistelli, E, De Bernardis, P, Chanial, P, D'Alessandro, G, Dashyan, G, De Petris, M, Grandsire, L, Hamilton, J.-Ch, Incardona, F, Landau, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M., Ricciardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Thermeau, J.-P, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Bélier, B, Baù, A, Bennett, D, Bergé, L, Bernard, J.-Ph, Bersanelli, M, Bigot-Sazy, M.-A, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Charlassier, R, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, Martin, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, Gonzalez, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Jules, E, Kaplan, J., Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Rasztocky, E, Ringegni, P, Romero, G, Spinelli, S, Stankowiak, G, Supanitsky, A, Timbie, P, Tomasi, M, Tucker, G, Tucker, C, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), and Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Published
2020

42. QUBIC I: Overview and Science Program

Author

Hamilton, J.-Ch, Mousset, L, Battistelli, E, Bigot-Sazy, M.-A, Chanial, P, Charlassier, R, D'Alessandro, G, De Bernardis, P, De Petris, M, Gamboa Lerena, M, Grandsire, L, Landau, S, Marnieros, S, Masi, S, Mennella, A, O'Sullivan, C, Piat, M., Riccardi, G, Scóccola, C, Stolpovskiy, M, Tartari, A, Torchinsky, S, Voisin, F, Zannoni, M, Ade, P, Alberro, J, Almela, A, Amico, G, Arnaldi, L, Auguste, D, Aumont, J, Azzoni, S, Banfi, S, Bélier, B, Baù, A, Bennett, D, Bergé, L, Bernard, J.-Ph, Bersanelli, M, Bonaparte, J, Bonis, J, Bunn, E, Burke, D, Buzi, D, Cavaliere, F, Chapron, C, Cobos Cerutti, A, Columbro, F, Coppolecchia, A, De Gasperis, G, De Leo, M, Dheilly, S, Duca, C, Dumoulin, L, Etchegoyen, A, Fasciszewski, A, Ferreyro, L, Fracchia, D, Franceschet, C, Ganga, K, García, B, García Redondo, M, Gaspard, M, Gayer, D, Gervasi, M, Giard, Martin, Gilles, V, Giraud-Heraud, Y, Gómez Berisso, M, Gonzalez, M, Gradziel, M, Hampel, M, Harari, D, Henrot-Versillé, S, Incardona, F, Jules, E, Kaplan, J., Kristukat, C, Lamagna, L, Loucatos, S, Louis, T, Maffei, B, Marty, W, Mattei, A, May, A, Mcculloch, M, Mele, L, Melo, D, Montier, L, Mundo, L, Murphy, J, Nati, F, Olivieri, E, Oriol, C, Paiella, A, Pajot, F, Passerini, A, Pastoriza, H, Pelosi, A, Perbost, C, Perciballi, M, Pezzotta, F, Piacentini, F, Piccirillo, L, Pisano, G, Platino, M, Polenta, G, Prêle, D, Puddu, R, Rambaud, D, Ringegni, P, Romero, G, Rasztocky, E, Salum, J, Schillaci, A, Scully, S, Spinelli, S, Stankowiak, G, Supanitsky, A, Thermeau, J.-P, Timbie, P, Tomasi, M, Tucker, C, Tucker, G, Viganò, D, Vittorio, N, Wicek, F, Wright, M, Zullo, A, Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), and Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Published
2020

46. A fecal near-infrared reflectance spectroscopy-aided methodology to determine goat dietary composition in a Mediterranean shrubland

Author

Glasser, T., Landau, S., Ungar, E.D., Perevolotsky, A., Dvash, L., Muklada, H., Kababya, D., and Walker J.W.

Subjects
Goats -- Food and nutrition, Goats -- Physiological aspects, Feces -- Properties, Reflectance spectroscopy -- Methods, Zoology and wildlife conservation
Abstract

An ecologically sound approach to the problem of brush encroachment onto Israeli rangeland might be their utilization by goats, but better knowledge of the feeding selectivity and ability of goats to thrive in encroached areas is required to devise viable production systems. Direct observation of bites could provide precise and accurate estimates of diet selection, but construction of a sufficiently large database would require too much time. The present study describes the first attempt to construct fecal near-infrared reflectance spectroscopy (NIRS) calibrations of the botanical and nutritional composition of the diet, and of the total intake of free-ranging goats, based on reference values determined with bite-count procedures. Calibration of fecal NIRS was based on 43 observations encompassing 3 goat breeds and 4 periods (spring, summer, and fall of 2004, and spring of 2005). Each observation comprised 242 min of continuous recording of the species and bite-type category selected by a single animal, on each of 2 consecutive days. The mass and chemical quality of each species and bite-type category--a total of more than 200,000 bites--were determined by using the simulated bite technique. Associated feces were scanned in the 1,100- to 2,500-nm range with a reflectance monochromator. Fecal NIRS calibrations had reasonable precision for dietary percentages of the 3 main botanical components: herbaceous vegetation (as one category; [R.sup.2] = 0.85), Phillyrea latifolia ([R.sup.2] = 0.89), and tannin-rich Pistacia lentiscus ([R.sup.2] = 0.77), with SE of cross-validation (SECV) of 7.8, 6.3, and 5.6% of DM, respectively. The [R.sup.2] values for dietary percentages of CP, NDF, IVDMD, and polyethylene glycol-binding tannins were 0.93, 0.88, 0.91, and 0.74, respectively, with SECV values of 0.9, 2.1, 4.3, and 0.9% of DM, respectively. The [R.sup.2] values for intakes of herbaceous vegetation, P. latifolia, and P. lentiscus were 0.80, 0.75, and 0.65, with SECV values of 71, 64, and 46 g of DM/d, respectively. The [R.sup.2] values for the daily nutrient intakes were below 0.60. Fecal NIRS data can be used to expand the databases of botanical and nutritional dietary composition when observed and resident animals graze simultaneously, but intakes should be calculated from fecal NIRS-predicted dietary DM composition and an independent evaluation of DMI. Key words: browse, diet composition, feces, goat, near-infrared reflectance spectroscopy

Published
2008

47. Cognitive behavioural therapy for adults with dissociative seizures (CODES): a pragmatic, multicentre, randomised controlled trial

Author

Goldstein, LH, Robinson, EJ, Mellers, JDC, Stone, J, Carson, A, Reuber, M, Medford, N, McCrone, P, Murray, J, Richardson, MP, Pilecka, I, Eastwood, C, Moore, M, Mosweu, I, Perdue, I, Landau, S, Chalder, T, and CODES study group

Abstract

BACKGROUND: Dissociative seizures are paroxysmal events resembling epilepsy or syncope with characteristic features that allow them to be distinguished from other medical conditions. We aimed to compare the effectiveness of cognitive behavioural therapy (CBT) plus standardised medical care with standardised medical care alone for the reduction of dissociative seizure frequency. METHODS: In this pragmatic, parallel-arm, multicentre randomised controlled trial, we initially recruited participants at 27 neurology or epilepsy services in England, Scotland, and Wales. Adults (≥18 years) who had dissociative seizures in the previous 8 weeks and no epileptic seizures in the previous 12 months were subsequently randomly assigned (1:1) from 17 liaison or neuropsychiatry services following psychiatric assessment, to receive standardised medical care or CBT plus standardised medical care, using a web-based system. Randomisation was stratified by neuropsychiatry or liaison psychiatry recruitment site. The trial manager, chief investigator, all treating clinicians, and patients were aware of treatment allocation, but outcome data collectors and trial statisticians were unaware of treatment allocation. Patients were followed up 6 months and 12 months after randomisation. The primary outcome was monthly dissociative seizure frequency (ie, frequency in the previous 4 weeks) assessed at 12 months. Secondary outcomes assessed at 12 months were: seizure severity (intensity) and bothersomeness; longest period of seizure freedom in the previous 6 months; complete seizure freedom in the previous 3 months; a greater than 50% reduction in seizure frequency relative to baseline; changes in dissociative seizures (rated by others); health-related quality of life; psychosocial functioning; psychiatric symptoms, psychological distress, and somatic symptom burden; and clinical impression of improvement and satisfaction. p values and statistical significance for outcomes were reported without correction for multiple comparisons as per our protocol. Primary and secondary outcomes were assessed in the intention-to-treat population with multiple imputation for missing observations. This trial is registered with the International Standard Randomised Controlled Trial registry, ISRCTN05681227, and ClinicalTrials.gov, NCT02325544. FINDINGS: Between Jan 16, 2015, and May 31, 2017, we randomly assigned 368 patients to receive CBT plus standardised medical care (n=186) or standardised medical care alone (n=182); of whom 313 had primary outcome data at 12 months (156 [84%] of 186 patients in the CBT plus standardised medical care group and 157 [86%] of 182 patients in the standardised medical care group). At 12 months, no significant difference in monthly dissociative seizure frequency was identified between the groups (median 4 seizures [IQR 0-20] in the CBT plus standardised medical care group vs 7 seizures [1-35] in the standardised medical care group; estimated incidence rate ratio [IRR] 0·78 [95% CI 0·56-1·09]; p=0·144). Dissociative seizures were rated as less bothersome in the CBT plus standardised medical care group than the standardised medical care group (estimated mean difference -0·53 [95% CI -0·97 to -0·08]; p=0·020). The CBT plus standardised medical care group had a longer period of dissociative seizure freedom in the previous 6 months (estimated IRR 1·64 [95% CI 1·22 to 2·20]; p=0·001), reported better health-related quality of life on the EuroQoL-5 Dimensions-5 Level Health Today visual analogue scale (estimated mean difference 6·16 [95% CI 1·48 to 10·84]; p=0·010), less impairment in psychosocial functioning on the Work and Social Adjustment Scale (estimated mean difference -4·12 [95% CI -6·35 to -1·89]; p

Published
2020

49. Hospital admissions for non-communicable disease in the UK military and associations with alcohol use and mental health:a data linkage study

Author

Goodwin, L., Leightley, D., Chui, Z. E., Landau, S., McCrone, P., Hayes, R. D., Jones, M., Wessely, S., Fear, N. T., Goodwin, L., Leightley, D., Chui, Z. E., Landau, S., McCrone, P., Hayes, R. D., Jones, M., Wessely, S., and Fear, N. T.

Abstract

Background Since the recent conflicts in Iraq and Afghanistan, the short-term focus of military healthcare research has been on the consequences of deployment for mental health and on those wounded or injured in combat. Now that these conflicts have ended for the UK Armed Forces, it is important to consider the longer term physical and mental health consequences, and just as importantly, the links between these. The aims of this study were to determine the most common physical conditions requiring a hospital admission in UK military personnel and whether they were more common in personnel with a mental health condition, smokers, and/or those misusing alcohol compared to those without. Methods Data linkage of a prospective UK military cohort study to electronic admitted patient care records for England, Wales and Scotland. Nine thousand nine hundred ninety military personnel completed phase 2 of a military cohort study (56% response rate, data collected from 2007 to 2009), with analyses restricted to 86% of whom provided consent for linkage to healthcare records (n = 8602). Ninety percent were male and the mean age at phase 2 was 36 years. The outcome was physical non communicable diseases (NCDs) requiring a hospital admission which occurred after phase 2 of the cohort when the mental health, smoking and alcohol use exposure variables had been assessed until the end of March 2014. Results The most common NCDs requiring a hospital admission were gastrointestinal disorders 5.62% (95% Confidence Intervals (CI) 5.04, 6.19) and joint disorders 5.60% (95% CI 5.02, 6.18). Number of NCDs requiring a hospital admission was significantly higher in those with a common mental disorder (Hazard ratio (HR) 1.40 (95% CI 1.16–1.68), post-traumatic stress disorder (HR 1.78 (95% CI 1.32–2.40)) and in current smokers (HR 1.35 (95% CI 1.12–1.64) compared to those without the disorder, and non-smokers, respectively. Conclusions Military personnel with a mental health problem are more like

Published
2020

50. A study protocol to assess the feasibility of conducting an evaluation trial of the ADVANCE integrated intervention to address both substance use and intimate partner abuse perpetration to men in substance use treatment

Author

Gilchrist, G, Landau, S, Radcliffe, P, McMurran, M, Feder, G, Easton, C, Parrott, S, Kirkpatrick, S, Henderson, J, Potts, L, Stephens-Lewis, D, Johnson, A, Love, B, Halliwell, G, Dheensa, S, Berbary, C, Li, J, Strang, J, Gilchrist, E, Gilchrist, G, Landau, S, Radcliffe, P, McMurran, M, Feder, G, Easton, C, Parrott, S, Kirkpatrick, S, Henderson, J, Potts, L, Stephens-Lewis, D, Johnson, A, Love, B, Halliwell, G, Dheensa, S, Berbary, C, Li, J, Strang, J, and Gilchrist, E

Abstract

BACKGROUND: Strong evidence exists that substance use is a contributory risk factor for intimate partner abuse (IPA) perpetration. Men in substance use treatment are more likely to perpetrate IPA than men from the general population. Despite this, referral pathways are lacking for this group. This trial will assess the feasibility of conducting an evaluation trial of a tailored integrated intervention to address substance use and IPA perpetration to men in substance use treatment. METHODS/DESIGN: ADVANCE is a multicentre, parallel-group individually randomised controlled feasibility trial, with a nested formative evaluation, comparing an integrated intervention to reduce IPA + substance use treatment as usual (TAU) to TAU only. One hundred and eight men who have perpetrated IPA in the past 12 months from community substance use treatment in London, the West Midlands, and the South West will be recruited. ADVANCE is a manualised intervention comprising 2-4 individual sessions (2 compulsory) with a keyworker to set goals, develop a personal safety plan and increase motivation and readiness, followed by a 12-session weekly group intervention delivered in substance use services. Men will be randomly allocated (ratio 1:1) to receive the ADVANCE intervention + TAU or TAU only. Men's female (ex) partners will be invited to provide outcome data and offered support from integrated safety services (ISS). Regular case management meetings between substance use and ISS will manage risk. Outcome measures will be obtained at the end of the intervention (approximately 4 months post-randomisation) for all male and female participants. The main objective of this feasibility trial is to estimate parameters required for planning a definitive trial including rates of consent, recruitment, and follow-up by site and group allocation. Nested formative evaluation including focus groups and in-depth interviews will explore the intervention's acceptability to participants, group facilitators

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results