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26 results on '"Lam,Ping Kuen"'

10. Adipose Tissue-Derived Mesenchymal Stem Cells (ADMSCs) and ADMSC-Derived Secretome Expedited Wound Healing in a Rodent Model – A Preliminary Study

Author

Ma, Hui, primary, Lam, Ping Kuen, additional, Siu, Wing Sum, additional, Tong, Cindy See Wai, additional, Lo, Kin Ki Yan, additional, Koon, Chi Man, additional, Wu, Xiao Xiao, additional, Li, Xiang, additional, Cheng, Wen, additional, Shum, Wai Ting, additional, and Leung, Ping Chung, additional

Published
2021
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11. Adipose Tissue-Derived Mesenchymal Stem Cells (ADMSCs) and ADMSC-Derived Secretome Expedited Wound Healing in a Rodent Model – A Preliminary Study

Author

Ma,Hui, Lam,Ping Kuen, Siu,Wing Sum, Tong,Cindy See Wai, Lo,Kin Ki Yan, Koon,Chi Man, Wu,Xiao Xiao, Li,Xiang, Cheng,Wen, Shum,Wai Ting, Leung,Ping Chung, Ma,Hui, Lam,Ping Kuen, Siu,Wing Sum, Tong,Cindy See Wai, Lo,Kin Ki Yan, Koon,Chi Man, Wu,Xiao Xiao, Li,Xiang, Cheng,Wen, Shum,Wai Ting, and Leung,Ping Chung

Abstract

Hui Ma,1,2 Ping Kuen Lam,3 Wing Sum Siu,1,2 Cindy See Wai Tong,3 Kin Ki Yan Lo,3 Chi Man Koon,1,2 Xiao Xiao Wu,1,2 Xiang Li,1,2 Wen Cheng,1,2 Wai Ting Shum,1,2 Ping Chung Leung1,2 1Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region of China; 2State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region of China; 3Chow Tai Fook-Cheng Yu Tung Surgical Stem Cell Research Center, Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region of ChinaCorrespondence: Ping Chung LeungInstitute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region of ChinaTel +85222528868Email pingcleung@cuhk.edu.hkIntroduction: The biological role of mesenchymal stem cells (MSCs) in wound healing has been demonstrated. However, there were limited studies on the healing effect of secretome which consists of many biological factors secreted by MSCs. In this study, we aimed to compare the therapeutic effects of secretome with MSCs on facilitating wound healing.Methods: Green fluorescent protein labelled adipose-derived MSCs (GFP-ADMSCs) or secretome was injected in the full-thickness skin excision model on SD rats. The wound healing process was evaluated by calculating the healing rate and the histological examinations on skin biopsy. The cell viability, proliferation and mobility of the rat dermal fibroblasts were compared after different treatments. The inflammatory response in macrophages was indicated by the level of nitric oxide (NO) and inflammatory cytokines through NO assay and ELISA.Results: On day 5 and day 14, both MSCs and secretome accelerated the wound healing, secretome further enhanced the process. GFP-MSCs were detected 10 days after transplantation. The level of IL-6 and TNF-α in blood was re

Published
2021

16. Neuroprotective effect of Da Chuanxiong Formula against cognitive and motor deficits in a rat controlled cortical impact model of traumatic brain injury

Author

Liu, Zhi-Ke, primary, Ng, Chun-Fai, additional, Shiu, Hoi-Ting, additional, Wong, Hing-Lok, additional, Chin, Wai-Ching, additional, Zhang, Jin-Fang, additional, Lam, Ping-Kuen, additional, Poon, Wai-Sang, additional, Lau, Clara Bik-San, additional, Leung, Ping-Chung, additional, and Ko, Chun-Hay, additional

Published
2018
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17. Topical Application of Mesenchymal Stromal Cells Ameliorated Liver Parenchyma Damage After Ischemia-Reperfusion Injury in an Animal Model

Author

Lam, Ping Kuen, primary, Chong, Charing Ching Ning, additional, Lo, Anthony Wing Ip, additional, Chan, Anthony Wing Hung, additional, Tong, Cindy See Wai, additional, Chin, Don Wai Ching, additional, Wong, Kenneth Hoi Kin, additional, Choy, Richard Kwong Wai, additional, Fung, Andrew Kai-Yip, additional, Wang, Yi Xiang, additional, To, Ka Fai, additional, and Lai, Paul Bo San, additional

Published
2017
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19. A traditional Chinese formula composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma (Da Chuanxiong Formula) suppresses inflammatory response in LPS -induced RAW 264.7 cells through inhibition of NF-κB pathway

Author

Liu, Zhi-Ke, primary, Ng, Chun-Fai, additional, Shiu, Hoi-Ting, additional, Wong, Hing-Lok, additional, Wong, Chun-Wai, additional, Li, Kai-Kai, additional, Zhang, Jin-Fang, additional, Lam, Ping-Kuen, additional, Poon, Wai-Sang, additional, Lau, Clara Bik-San, additional, Leung, Ping-Chung, additional, and Ko, Chun-Hay, additional

Published
2017
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20. The aqueous extract of rhizome of Gastrodia elata Blume attenuates locomotor defect and inflammation after traumatic brain injury in rats

Author

Ng, Chun-Fai, primary, Ko, Chun-Hay, additional, Koon, Chi-Man, additional, Chin, Wai-Ching, additional, Kwong, Hiu Ching Sonya Themis, additional, Lo, Anthony Wing-Ip, additional, Wong, Hing-Lok, additional, Fung, Kwok-Pui, additional, Lau, Clara Bik-San, additional, Lam, Ping-Kuen, additional, Poon, Wai Sang, additional, and Leung, Ping-Chung, additional

Published
2016
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23. Evaluation of human skin substitute for burn wound coverage based on cultured epidermal autograft.

Author

Lam, Ping-kuen., Chinese University of Hong Kong Graduate School. Division of Surgical Sciences., Lam, Ping-kuen., and Chinese University of Hong Kong Graduate School. Division of Surgical Sciences.

Abstract

Ping-kuen Lam., "May 1998.", Thesis (Ph.D.)--Chinese University of Hong Kong, 1998., Includes bibliographical references (p. 109-121)., Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web., Mode of access: World Wide Web., s in English and Chinese., http://library.cuhk.edu.hk/record=b6073136, Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Published
1998

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