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8. Determinants of V̇+O2 peak Changes After Aerobic Training in Coronary Heart Disease Patients.

Author

Girault, Axel, Leprêtre, Pierre-Marie, Trachsel, Lukas-Daniel, Besnier, Florent, Boidin, Maxime, Lalongé, Julie, Juneau, Martin, Bherer, Louis, Nigam, Anil, and Gayda, Mathieu

Subjects
EXERCISE physiology, CORONARY disease, RESEARCH funding, PULMONARY gas exchange, DESCRIPTIVE statistics, CARDIOPULMONARY system, CARDIAC output, HEART beat, AEROBIC exercises, OXYGEN consumption, EXERCISE tests, CARDIAC rehabilitation
Abstract

This study aimed to highlight the ventilatory and circulatory determinants of changes in ˙VO2 peak after exercise-based cardiac rehabilitation (ECR) in patients with coronary heart disease (CHD). Eighty-two CHD patients performed, before and after a 3-month ECR, a cardiopulmonary exercise testing (CPET) on a bike with gas exchanges measurements (˙VO2 peak, minute ventilation, i. e., ˙VE), and cardiac output (Q˙c). The arteriovenous difference in O2 (C(a-v¯)O2) and the alveolar capillary gradient in O2 (PAi-aO2) were calculated using Fick's laws. Oxygen uptake efficiency slope (OUES) was calculated. A 5.0% cut off was applied for differentiating non- (NR: ˙VO2 <0.0%), low (LR: 0.0≤ ∆˙VO2 <5.0%), moderate (MR: 5.0≤∆˙VO2 < 10.0%), and high responders (HR: ∆˙VO2 ≥10.0%) to ECR. A total of 44% of patients were HR (n=36), 20% MR (n=16), 23% LR (n=19), and 13% NR (n=11). For HR, the ˙VO2 peak increase (p<0.01) was associated with increases in ˙VE (+12.8±13.0 L/min, p<0.01), (+1.0±0.9 L/min, p<0.01), and C(a-v¯)O2 (+2.3±2.5 mLO2 /100 mL, p<0.01). MR patients were characterized by+6.7±19.7 L/min increase in ˙VE (p=0.04) and+0.7±1.0 L/min of Q˙c (p<0.01). ECR induced decreases in ˙VE (p=0.04) and C(a-v¯)O2 (p<0.01) and a Q˙c increase in LR and NR patients (p<0.01). Peripheral and ventilatory responses more than central adaptations could be responsible for the ˙VO2 peak change with ECR in CHD patients. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Impact of aerobic training periodisation on global and regional right ventricular strain in coronary heart disease.

Author

Trachsel, Lukas D., David, Louis-Philippe, Gayda, Mathieu, Boidin, Maxime, Lalongé, Julie, Juneau, Martin, Nigam, Anil, and Henri, Christine

Subjects
ENERGY metabolism, AEROBIC exercises, RIGHT heart ventricle, EXERCISE physiology, WORLD health, CORONARY disease, RANDOMIZED controlled trials, CYCLES, DESCRIPTIVE statistics, HEART physiology, STATISTICAL sampling, LONGITUDINAL method
Abstract

Copyright of Applied Physiology, Nutrition & Metabolism is the property of Canadian Science Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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17. The impact of high‐intensity interval training on ventricular remodeling in patients with a recent acute myocardial infarction—A randomized training intervention pilot study

Author

Trachsel, Lukas‐Daniel, primary, David, Louis‐Philippe, additional, Gayda, Mathieu, additional, Henri, Christine, additional, Hayami, Douglas, additional, Thorin‐Trescases, Nathalie, additional, Thorin, Éric, additional, Blain, Mélissa‐Anne, additional, Cossette, Mariève, additional, Lalongé, Julie, additional, Juneau, Martin, additional, and Nigam, Anil, additional

Published
2019
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20. Exercise Lowers Plasma Angiopoietin-Like 2 in Men with Post-Acute Coronary Syndrome

Author

Thorin-Trescases, Nathalie, primary, Hayami, Doug, additional, Yu, Carol, additional, Luo, Xiaoyan, additional, Nguyen, Albert, additional, Larouche, Jean-François, additional, Lalongé, Julie, additional, Henri, Christine, additional, Arsenault, André, additional, Gayda, Mathieu, additional, Juneau, Martin, additional, Lambert, Jean, additional, Thorin, Eric, additional, and Nigam, Anil, additional

Published
2016
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21. Lower Methylation of the ANGPTL2 Gene in Leukocytes from Post-Acute Coronary Syndrome Patients

Author

Nguyen, Albert, primary, Mamarbachi, Maya, additional, Turcot, Valérie, additional, Lessard, Samuel, additional, Yu, Carol, additional, Luo, Xiaoyan, additional, Lalongé, Julie, additional, Hayami, Doug, additional, Gayda, Mathieu, additional, Juneau, Martin, additional, Thorin-Trescases, Nathalie, additional, Lettre, Guillaume, additional, Nigam, Anil, additional, and Thorin, Eric, additional

Published
2016
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