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Background: Appropriate feeding practices in early life are widely identified as important determinants for growth and development in children. Identifying and promoting the best feeding practice for HIV exposed infants has been a real challenge in the developing world. Aims and Objectives: To study the impact of type of feeding practices on growth, development and occurrence of infections in HIV exposed infants versus HIV non-exposed infants. Methods: A total of 105 infants were enrolled in the study and divided in two primary groups, HIV-exposed infants (50) and HIV non-exposed control infants (55). Thereafter each group was divided according to the feeding pattern as exclusive breast fed, top fed and mixed fed. All infants were followed from birth monthly till 6 months of age and at each visit they were examined for rate of infections, anthropometry developmental milestones, feeding methods were recorded. Results: There was a significant increase in infections among top fed and mixed fed babies in both control and exposed group compared to exclusive breast fed group (p 0.05). Growth was affected in top fed and mixed fed exposed infants compared to exclusive breast fed infants. Development was affected most in the mixed fed infants but difference was statistically insignificant. Conclusion: Exclusive breast feeding is a choice of infant feeding, as it causes lesser infections and better growth and development of the child.