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1. Electroacupuncture Ameliorates Depression-Like Behaviors in Post-Stroke Rats via Activating AMPK-Mediated Mitochondrial Function

Author: Ding Z, Gao J, Feng Y, Wang M, Zhao H, Wu R, Zheng X, Feng X, and Lai M
Subjects: electroacupuncture, post-stroke depression, mitochondria, ampk, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract: Zhimin Ding,1,&ast; Jing Gao,2,&ast; Yixuan Feng,1,&ast; Mengyu Wang,1 Huandong Zhao,1 Ruonan Wu,1 Xinyue Zheng,1 Xiaodong Feng,1,2 Mingyin Lai3 1School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou, People’s Republic of China; 2Department of Rehabilitation Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, People’s Republic of China; 3School of Traditional Chinese Medicine, Hainan Medical University, Haikou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiaodong Feng; Mingyin Lai, Email fxd0502@163.com; dearl_0524@163.comBackground: Post-stroke depression (PSD) is one of the most common complications of stroke. Electroacupuncture (EA) is an effective traditional Chinese medicine treatment for PSD, which is widely used in clinical settings. EA has a significant therapeutic effect against PSD, but the mechanism is still unclear. This study aimed to determine whether EA ameliorates depression-like behaviors in PSD rats by regulating the adenosine 5’-monophosphate (AMP)-activated protein kinase (AMPK)-mediated mitochondrial function.Methods: Middle cerebral artery occlusion (MCAO) and chronic unpredictable mild stress (CUMS) were used to develop a PSD rat model. To elucidate the role of AMPK in EA treatment, compound C, a selective inhibitor of AMPK, was injected into the lateral ventricle of rats before EA treatment. EA treatment was performed for 14 consecutive days for 30 min per day after PSD modeling. A modified Zea-Longa five-point scale scoring system was used to determine neurologic function in MCAO rats. Behavioral tests were conducted to evaluate depression-like phenotypes in rats. Depression-like behaviors were tested by sucrose preference test (SPT), novelty suppressed feeding test (NSFT), and open-field test (OFT). The structure and morphology of the prefrontal cortex were observed by histopathological hematoxylin-eosin (HE) and Nissl staining. The mitochondrial morphology and function were analyzed by colorimetry, chemiluminescence, Western blotting, and quantitative real-time polymerase chain reaction (qRT-PCR).Results: EA treatment successfully ameliorated depression-like behaviors, upregulated AMPK expression, and improved mitochondrial function. However, AMPK inhibition by Compound C exacerbated depression-like behaviors and aggravated neuronal and mitochondrial injury in PSD rats.Conclusion: EA treatment improved depression-like behaviors in PSD rats and promoted mitochondrial function by activating AMPK.Keywords: electroacupuncture, post-stroke depression, mitochondria, AMPK
Published: 2023

2. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kish, A., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xiao, X., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: DarkSide-20k (DS-20k) is a dark matter detection experiment under construction at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy. It utilises ~100 t of low radioactivity argon from an underground source (UAr) in its inner detector, with half serving as target in a dual-phase time projection chamber (TPC). The UAr cryogenics system must maintain stable thermodynamic conditions throughout the experiment's lifetime of >10 years. Continuous removal of impurities and radon from the UAr is essential for maximising signal yield and mitigating background. We are developing an efficient and powerful cryogenics system with a gas purification loop with a target circulation rate of 1000 slpm. Central to its design is a condenser operated with liquid nitrogen which is paired with a gas heat exchanger cascade, delivering a combined cooling power of >8 kW. Here we present the design choices in view of the DS-20k requirements, in particular the condenser's working principle and the cooling control, and we show test results obtained with a dedicated benchmarking platform at CERN and LNGS. We find that the thermal efficiency of the recirculation loop, defined in terms of nitrogen consumption per argon flow rate, is 95 % and the pressure in the test cryostat can be maintained within $\pm$(0.1-0.2) mbar. We further detail a 5-day cool-down procedure of the test cryostat, maintaining a cooling rate typically within -2 K/h, as required for the DS-20k inner detector. Additionally, we assess the circuit's flow resistance, and the heat transfer capabilities of two heat exchanger geometries for argon phase change, used to provide gas for recirculation. We conclude by discussing how our findings influence the finalisation of the system design, including necessary modifications to meet requirements and ongoing testing activities., Comment: 45 pages, 24 figures
Published: 2024

3. DarkSide-20k sensitivity to light dark matter particles

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Walczak, M. B., Wang, Y., Wang, H., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The dual-phase liquid argon time projection chamber is presently one of the leading technologies to search for dark matter particles with masses below 10 GeV/c$^2$. This was demonstrated by the DarkSide-50 experiment with approximately 50 kg of low-radioactivity liquid argon as target material. The next generation experiment DarkSide-20k, currently under construction, will use 1,000 times more argon and is expected to start operation in 2027. Based on the DarkSide-50 experience, here we assess the DarkSide-20k sensitivity to models predicting light dark matter particles, including Weakly Interacting Massive Particles (WIMPs) and sub-GeV/c$^2$ particles interacting with electrons in argon atoms. With one year of data, a sensitivity improvement to dark matter interaction cross-sections by at least one order of magnitude with respect to DarkSide-50 is expected for all these models. A sensitivity to WIMP--nucleon interaction cross-sections below $1\times10^{-42}$ cm$^2$ is achievable for WIMP masses above 800 MeV/c$^2$. With 10 years exposure, the neutrino fog can be reached for WIMP masses around 5 GeV/c$^2$., Comment: submitted to Nature Communications
Published: 2024

4. The SNEWS 2.0 Alert Software for the Coincident Detection of Neutrinos from Core-Collapse Supernovae

Author: Kara, M., Torres-Lara, S., Baxter-Depoian, A., BenZvi, S., Molla, M. Colomer, Habig, A., Kneller, J. P., Lai, M., Lang, R. F., Linvill, M., Milisavljevic, D., Migenda, J., Orr, C., Scholberg, K., Smolsky, J., Tseng, J., Tunnell, C. D., Vasel, J., and Sheshukov, A.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract: The neutrino signal from the next galactic core-collapse supernova will provide an invaluable early warning of the explosion. By combining the burst trigger from several neutrino detectors, the location of the explosion can be triangulated minutes to hours before the optical emission becomes visible, while also reducing the rate of false-positive triggers. To enable multi-messenger follow-up of nearby supernovae, the SuperNova Early Warning System 2.0 (SNEWS 2.0) will produce a combined alert using a global network of neutrino detectors. This paper describes the trigger publishing and alert formation framework of the SNEWS 2.0 network. The framework is built on the HOPSKOTCH publish-subscribe system to easily incorporate new detectors into the network, and it implements a coincidence system to form alerts and estimate a false-positive rate for the combined triggers. The paper outlines the structure of the SNEWS 2.0 software and the initial testing of coincident signals.
Published: 2024

5. Relative Measurement and Extrapolation of the Scintillation Quenching Factor of $\alpha$-Particles in Liquid Argon using DEAP-3600 Data

Author: The DEAP Collaboration, Adhikari, P., Alpízar-Venegas, M., Amaudruz, P. -A., Anstey, J., Auty, D. J., Batygov, M., Beltran, B., Bina, C. E., Bonivento, W., Boulay, M. G., Bueno, J. F., Cai, B., Cárdenas-Montes, M., Choudhary, S., Cleveland, B. T., Crampton, R., Daugherty, S., DelGobbo, P., Di Stefano, P., Dolganov, G., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Ford, R. J., Gahan, D., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Giménez-Alcázar, A., Goeldi, D., Gorel, P., Graham, K., Hallin, A. L., Hamstra, M., Haskins, S., Hu, J., Hucker, J., Hugues, T., Ilyasov, A., Jigmeddorj, B., Jillings, C. J., Kaur, G., Yazdi, M. Khoshraftar, Kemp, A., Kuźniak, M., La Zia, F., Lai, M., Langrock, S., Lehnert, B., Levashko, N., Lissia, M., Luzzi, L., Machulin, I., Maru, A., Mason, J., McDonald, A. B., McElroy, T., McLaughlin, J. B., Mielnichuk, C., Mirasola, L., Moharana, A., Monroe, J., Murray, A., Ng, C., Oliviéro, G., Olszewski, M., Pal, S., Papi, D., Park, B., Perry, M., Pesudo, V., Pollmann, T. R., Rad, F., Rethmeier, C., Retière, F., Roszkowski, L., Santorelli, R., Schuckman II, F. G., Seth, S., Shalamova, V., Skensved, P., Smirnova, T., Sobotkiewich, K., Sonley, T., Sosiak, J., Soukup, J., Stainforth, R., Stringer, M., Tang, J., Vázquez-Jáuregui, E., Viel, S., Vyas, B., Walczak, M., Walding, J., Ward, M., Westerdale, S., and Wormington, R.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: The knowledge of scintillation quenching of $\alpha$-particles plays a paramount role in understanding $\alpha$-induced backgrounds and improving the sensitivity of liquid argon-based direct detection of dark matter experiments. We performed a relative measurement of scintillation quenching in the MeV energy region using radioactive isotopes ($^{222}$Rn, $^{218}$Po and $^{214}$Po isotopes) present in trace amounts in the DEAP-3600 detector and quantified the uncertainty of extrapolating the quenching factor to the low-energy region., Comment: 9 pages, 6 figures (added 1 figure, revised 3 figures), 2 tables, revised sections 3, 4, 5. Accepted in Eur. Phys. J. C
Published: 2024

6. Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells

Author: Bayat N, McOrist N, Ariotti N, Lai M, Sia KCS, Li Y, Grace JL, Quinn JF, Whittaker MR, Kavallaris M, Davis TP, and Lock RB
Subjects: nanoparticles, targeting, endocytosis, leukemia, flow cytometry, microscopy, Medicine (General), R5-920
Abstract: Narges Bayat,1,2 Nathan McOrist,1 Nicholas Ariotti,3,4 May Lai,5 Keith CS Sia,1,2 Yuhuan Li,5 James L Grace,5 John F Quinn,5 Michael R Whittaker,5 Maria Kavallaris,2,6,7 Thomas P Davis,5,8,9,* Richard B Lock1,2,* 1Leukemia Biology Program, Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; 2School of Women’s and Children’s Health, Faculty of Medicine, University of New South Wales, Sydney, Australia; 3Electron Microscope Unit, Mark Wainwright Analytical Centre, Chemical Sciences Building, University of New South Wales, Sydney, NSW, Australia; 4School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia; 5ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia; 6Tumor Biology and Targeting Program, Children’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia; 7Australian Centre for Nanomedicine, ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of New South Wales, Sydney, NSW, Australia; 8Department of Chemistry, University of Warwick, Coventry, UK; 9Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia*These authors contributed equally to this workCorrespondence: Richard B LockChildren’s Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, PO Box 81, Randwick 2031, NSW, AustraliaTel +61 2 9385 2513Fax +61 2 9662 6583Email rlock@ccia.org.auPurpose: Directing nanoparticles to cancer cells without using antibodies is of great interest. Subtle changes to the surface chemistry of nanoparticles can significantly affect their biological fate, including their propensity to associate with different cell populations. For instance, nanoparticles functionalized with thiol-reactive groups can potentially enhance association with cells that over-express cell-surface thiol groups. The potential of such an approach for enhancing drug delivery for childhood acute lymphoblastic leukemia (ALL) cells has not been investigated. Herein, we investigate the impact of thiol-reactive star polymers on the cellular association and the mechanisms of uptake of the nanoparticles.Methods: We prepared fluorescently labeled star polymers functionalized with an mPEG brush corona and pyridyl disulfide to examine how reactivity to exofacial thiols impacts cellular association with ALL cells. We also studied how variations to the mPEG brush composition could potentially be used as a secondary method for controlling the extent of cell association. Specifically, we examined how the inclusion of shorter diethylene glycol brush moieties into the nanoparticle corona could be used to further influence cell association.Results: Star polymers incorporating both thiol-reactive and diethylene glycol brush moieties exhibited the highest cellular association, followed by those functionalized solely with thiol reactive groups compared to control nanoparticles in T and B pediatric ALL patient-derived xenografts harvested from the spleens and bone marrow of immunodeficient mice. Transfection of cells with an early endosomal marker and imaging with correlative light and electron microscopy confirmed cellular uptake. Endocytosis inhibitors revealed dynamin-dependent clathrin-mediated endocytosis as the main uptake pathway for all the star polymers.Conclusion: Thiol-reactive star polymers having an mPEG brush corona that includes a proportion of diethylene glycol brush moieties represent a potential strategy for improved leukemia cell delivery.Keywords: nanoparticles, targeting, endocytosis, leukemia, flow cytometry, microscopy
Published: 2019

7. Investigation Of Vitamin B12-Modified Amphiphilic Sodium Alginate Derivatives For Enhancing The Oral Delivery Efficacy Of Peptide Drugs

Author: Long L, Lai M, Mao X, Luo J, Yuan X, Zhang LM, Ke Z, Yang L, and Deng DYB
Subjects: Nanoparticle, Insulin, Human colon adenocarcinoma cell, small intestinal absorption efficacy, Medicine (General), R5-920
Abstract: Lingli Long,1,2,* Minghua Lai,3,* Xuhong Mao,4 Jiahao Luo,3 Xin Yuan,2 Li-Ming Zhang,4 Zunfu Ke,5 Liqun Yang,3 David YB Deng1,2 1Department of Research Center of Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, People’s Republic of China; 2Department of Scientific Research Center and Orthopedic, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, People’s Republic of China; 3Department of Polymer and Material Science, School of Chemistry, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Provincial Key Laboratory for High Performance Polymer-based Composites, Sun Yat-sen University, Guangzhou 510275, People’s Republic of China; 4Faculty of Materials Science and Engineering, Sun Yat-sen University, Guangzhou 510275, People’s Republic of China; 5Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, People’s Republic of China*These authors contributed equally to this workCorrespondence: David YB DengDepartment of Research Center of Translational Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, People’s Republic of ChinaEmail dengyub@mail.sysu.edu.cnLiqun YangDepartment of Polymer and Material Science, School of Chemistry, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Provincial Key Laboratory for High Performance Polymer-based Composites, Sun Yat-sen University, Guangzhou 510275, People’s Republic of ChinaEmail yanglq@mail.sysu.edu.cnPurpose: Peptide drugs have been used in therapy various diseases. However, the poor bioavailability of peptide drugs for oral administration has limited their clinical applications, on account of the acidic environment and digestive enzymes inside the human gastrointestinal tract. To enhance stability in the human gastrointestinal tract, bioavailability, and targeted drug delivery of peptide drugs through oral administration, a vitamin B12-modified amphiphilic sodium alginate derivative (CSAD-VB12) was synthesized.Materials and methods: A vitamin B12-modified amphiphilic sodium alginate derivative (CSAD-VB12) was synthesized via the N,N’-dicyclohexylcarbodiimide active method at room temperature, and then characterized using FTIR and 1H NMR spectroscopy. Insulin was used as a model peptide drug and the insulin-loaded CSAD-VB12 (CSAD-VB12/insulin) nanoparticles with negative zeta potentials were prepared in PBS (pH=7.4). Scanning electron microscopy was used to observe CSAD-VB12/insulin as spherical nanoparticles. The CSAD-VB12 derivatives and CSAD-VB12/insulin nanoparticles displayed nontoxicity towards the human colon adenocarcinoma (Caco-2) cells by CCK-8 test. Caco-2 cell model was used to measure the apparent permeability (Papp) of insulin, CSAD/insulin and CSAD-VB12/insulin. Furthermore, confocal was used to confirm the endocytosis of intestinal enterocytes. Type 1 diabetes mice were used to evaluate the intestinal absorption and retention effect of test nanoparticles.Results: They were observed as spherical nanoparticles in the size of 30–50 nm. The CSAD-VB12 derivatives and CSAD-VB12/insulin nanoparticles displayed nontoxicity towards the human colon adenocarcinoma (Caco-2) cells. Comparing with insulin and the CSAD/insulin nanoparticles, the CSAD-VB12/insulin nanoparticles exhibited higher permeation ability through intestinal enterocytes in the Caco-2 cell model. Oral administration of the CSAD-VB12/insulin nanoparticles to Type 1 diabetic mice yields higher intestinal retention effect, targeted absorption, and outstanding efficacy.Conclusion: CSAD-VB12 derivatives enhance the small intestinal absorption efficacy and retention of peptide by oral administration, which indicated that it could be a promising candidate for oral peptide delivery in the prospective clinical application.Keywords: nanoparticle, insulin, human colon adenocarcinoma cell, small intestinal absorption efficacy
Published: 2019

8. A new hybrid gadolinium nanoparticles-loaded polymeric material for neutron detection in rare event searches

Author: Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cavallo, D., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galinski, G., Gallina, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peddis, D., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Sadashivajois, S., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Slimani, S., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Tonazzo, A., Torres-Lara, S., Tosi, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Vicini, S., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczynski, R., Wojcik, M. M., Wojcik, M., Wright, T., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Experiments aimed at direct searches for WIMP dark matter require highly effective reduction of backgrounds and control of any residual radioactive contamination. In particular, neutrons interacting with atomic nuclei represent an important class of backgrounds due to the expected similarity of a WIMP-nucleon interaction, so that such experiments often feature a dedicated neutron detector surrounding the active target volume. In the context of the development of DarkSide-20k detector at INFN Gran Sasso National Laboratory (LNGS), several R&D projects were conceived and developed for the creation of a new hybrid material rich in both hydrogen and gadolinium nuclei to be employed as an essential element of the neutron detector. Thanks to its very high cross-section for neutron capture, gadolinium is one of the most widely used elements in neutron detectors, while the hydrogen-rich material is instrumental in efficiently moderating the neutrons. In this paper results from one of the R&Ds are presented. In this effort the new hybrid material was obtained as a poly(methyl methacrylate) (PMMA) matrix, loaded with gadolinium oxide in the form of nanoparticles. We describe its realization, including all phases of design, purification, construction, characterization, and determination of mechanical properties of the new material.
Published: 2024
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9. Manejo de derrame pericárdico: revisión sistemática de la literatura

Author: Guillermo O. Trout, Renata De La Hoz, Lai M. Alfaro, Angie P. Córdoba, and Gilberto A. Consuegra
Subjects: Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract: Resumen: Objetivo: Revisar sistemáticamente la efectividad del tratamiento no quirúrgico para el manejo del derrame pericárdico moderado o severo. Metodología: Se realizó una búsqueda sistemática desde febrero hasta junio de 2016 en las bases de datos Pub Med, SciELO y Lilacs, en inglés y español. Los términos de búsqueda utilizados fueron: Pericardial Effusion and Acute Pericarditis, Treatment, Therapy, Therapeutics, Management. Se eligieron artículos publicados entre 2011 y 2016 que abordaran el tratamiento del derrame pericárdico no quirúrgico y la pericarditis aguda. Se excluyeron artículos que evaluaran el manejo de taponamiento cardíaco, pericarditis constrictiva y derrame pericárdico por lesión miocárdica. La selección de artículos estuvo a cargo de dos evaluadores y, en caso de discrepancias, se consultó un tercer evaluador. Resultados: Se identificaron un total de 2.998 referencias; posteriormente, se seleccionaron 138 artículos, de los cuales se evaluaron sus resúmenes. Se eligieron dos artículos para la lectura a texto completo, y se aplicaron a estos las guías Strobe, para estudios observacionales, y Consort, para ensayos clínicos aleatorizados. Se evidenció que la pericarditis recurrente ocurrió en 26 de los 120 pacientes en el grupo de colchicina y en 51 de 120 en el grupo placebo, RRR: 0, 49 (IC = 0, 24–0, 65; p = 0, 0009). Conclusiones: la colchicina asociada a antiinflamatorios no esteroides evidenció ser efectiva en la pericarditis aguda idiopática y asimismo en sus recurrencias. Sin embargo, aún es necesario consultar más ensayos clínicos con mayor tamaño de muestra para determinar con exactitud la efectividad del tratamiento. Abstract: Objective: To present a systematic review of the effectiveness of non-surgical treatment for the management of moderate or severe pericardial effusion. Methodology: A systematic search was made from February to June 2016 in the databases of Pub Med, SciELO, and Lilacs, in English and Spanish. The search terms used were: Pericardial Effusion and Acute Pericarditis, Treatment, Therapy, Therapeutics, Management. Articles published between 2011 and 2016 that approached the non-surgical treatment of pericardial effusion and acute pericarditis were chosen. Articles that were excluded were those that evaluated cardiac tamponade, constrictive pericarditis, and pericardial effusion due to a myocardial lesion. The selection of the articles was the responsibility of two evaluators and, in case of discrepancies, a third evaluator was consulted. Result: A total of 2,998 references where identified, from which 138 articles were later selected, and their Abstracts were evaluated. Two articles were chosen in order to read the full text, and the Strobe guidelines for observational studies and the Consort guidelines for randomised clinical trials were used. It was shown that recurrent pericarditis occurred in 26 of the 120 patients in the colchicine group, and in 51 of 120 in the placebo group, with a relative risk ratio (RRR): 0.49 (95% CI; 0.24– 0.65; P=.0009). Conclusions: Colchicine combined with non-steroidal anti-inflammatory drugs showed to be effective in acute idiopathic pericarditis, as well as in their recurrences. However, more clinical trials with a larger sample size need to be consulted in order to determine the effectiveness of the treatment with more accuracy. Palabras clave: Pericarditis ;Tratamiento, Pericardio, Keywords: Pericarditis, Treatment, Pericardial
Published: 2018
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10. Nonlinear Control for Constraint-tuning Modified-mode Ultrasonic Actuating Linear Stage

Author: Wen, F.-L., Lai, M.-H., and Wen, C.-P.
Published: 2024
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11. Martensitic structure evolution during deformation and its correlation with solution temperature in metastable β titanium alloys

Author: Zhang, J. M., Wu, X. W., Wang, Y. J., Zhang, X. W., Lai, M. J., and Li, J. S.
Published: 2024
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12. Long-term temporal stability of the DarkSide-50 dark matter detector

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics, Physics - Instrumentation and Detectors
Abstract: The stability of a dark matter detector on the timescale of a few years is a key requirement due to the large exposure needed to achieve a competitive sensitivity. It is especially crucial to enable the detector to potentially detect any annual event rate modulation, an expected dark matter signature. In this work, we present the performance history of the DarkSide-50 dual-phase argon time projection chamber over its almost three-year low-radioactivity argon run. In particular, we focus on the electroluminescence signal that enables sensitivity to sub-keV energy depositions. The stability of the electroluminescence yield is found to be better than 0.5%. Finally, we show the temporal evolution of the observed event rate around the sub-keV region being consistent to the background prediction., Comment: 13 pages, 5 figures
Published: 2023
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13. Directionality of nuclear recoils in a liquid argon time projection chamber

Author: Collaboration, The DarkSide-20k, Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Corona, M. Atzori, Ave, M., Avetisov, I. Ch., Azzolini, O., Back, H. O., Balmforth, Z., Barrado-Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Cappello, G., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Vilda, E. Conde, Consiglio, L., Copello, S., Covone, G., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Davini, S., de Candia, A., De Cecco, S., De Gruttola, D., De Filippis, G., Dell'Aquila, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Dionisi, C., Di Stefano, P., Dolganov, G., Dordei, F., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemmerich, N., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Li, X., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Marik, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pesudo, V., Piacentini, S., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sosa, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., John, T. Vallivilayil, Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors
Abstract: The direct search for dark matter in the form of weakly interacting massive particles (WIMP) is performed by detecting nuclear recoils (NR) produced in a target material from the WIMP elastic scattering. A promising experimental strategy for direct dark matter search employs argon dual-phase time projection chambers (TPC). One of the advantages of the TPC is the capability to detect both the scintillation and charge signals produced by NRs. Furthermore, the existence of a drift electric field in the TPC breaks the rotational symmetry: the angle between the drift field and the momentum of the recoiling nucleus can potentially affect the charge recombination probability in liquid argon and then the relative balance between the two signal channels. This fact could make the detector sensitive to the directionality of the WIMP-induced signal, enabling unmistakable annual and daily modulation signatures for future searches aiming for discovery. The Recoil Directionality (ReD) experiment was designed to probe for such directional sensitivity. The TPC of ReD was irradiated with neutrons at the INFN Laboratori Nazionali del Sud, and data were taken with 72 keV NRs of known recoil directions. The direction-dependent liquid argon charge recombination model by Cataudella et al. was adopted and a likelihood statistical analysis was performed, which gave no indications of significant dependence of the detector response to the recoil direction. The aspect ratio R of the initial ionization cloud is estimated to be 1.037 +/- 0.027 and the upper limit is R < 1.072 with 90% confidence level, Comment: 20 pages, 10 figures, submitted to Eur. Phys. J. C
Published: 2023

14. Search for dark matter annual modulation with DarkSide-50

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: Dark matter induced event rate in an Earth-based detector is predicted to show an annual modulation as a result of the Earth's orbital motion around the Sun. We searched for this modulation signature using the ionization signal of the DarkSide-50 liquid argon time projection chamber. No significant signature compatible with dark matter is observed in the electron recoil equivalent energy range above $40~{\rm eV_{ee}}$, the lowest threshold ever achieved in such a search., Comment: 8 pages, 4 figures
Published: 2023

15. Precision Measurement of the Specific Activity of $^{39}$Ar in Atmospheric Argon with the DEAP-3600 Detector

Author: Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P. -A., Anstey, J., Araujo, G. R., Auty, D. J., Baldwin, M., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, M., Chen, Y., Choudhary, S., Cleveland, B. T., Corning, J. M., Crampton, R., Cranshaw, D., Daughtery, S., DelGobbo, P., Dering, K., Di Stefano, P., DiGioseffo, J., Dolganov, G., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Florian, S., Flower, A., Ford, R. J., Gagnon, R., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Giménez-Alcázar, A., Goeldi, D., Golovko, V. V., Gorel, P., Graham, K., Grant, D. R., Grobov, A., Hallin, A. L., Hamstra, M., Harvey, P. J., Haskins, S., Hearns, C., Hu, J., Hucker, J., Hugues, T., Ilyasov, A., Jigmeddorj, B., Jillings, C. J., Joy, A., Kamaev, O., Kaur, G., Kemp, A., Kuźniak, M., La Zia, F., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., LePage-Bourbonnais, J., Levashko, N., Lidgard, J., Lindner, T., Lissia, M., Lock, J., Machulin, I., Majewski, P., Maru, A., Mason, J., McDonald, A. B., McElroy, T., McGinn, T., McLaughlin, J. B., Mehdiyev, R., Mielnichuk, C., Mirasola, L., Monroe, J., Nadeau, P., Nantais, C., Ng, C., Noble, A. J., O'Dwyer, E., Oliviéro, G., Ouellet, C., Pal, S., Papi, D., Pasuthip, P., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Rad, F., Rand, E. T., Rethmeier, C., Retière, F., García, I. Rodríguez, Roszkowski, L., Ruhland, J. B., Santorelli, R., Schuckman II, F. G., Seeburn, N., Seth, S., Shalamova, V., Singhrao, K., Skensved, P., Smith, N. J. T., Smith, B., Sobotkiewich, K., Sonley, T., Sosiak, J., Soukup, J., Stainforth, R., Stone, C., Strickland, V., Stringer, M., Sur, B., Tang, J., Vázquez-Jáuregui, E., Veloce, L., Viel, S., Vyas, B., Walczak, M., Walding, J., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: The specific activity of the beta decay of $^{39}$Ar in atmospheric argon is measured using the DEAP-3600 detector. DEAP-3600, located 2 km underground at SNOLAB, uses a total of (3269 $\pm$ 24) kg of liquid argon distilled from the atmosphere to search for dark matter. This detector with very low background uses pulseshape discrimination to differentiate between nuclear recoils and electron recoils and is well-suited to measure the decay of $^{39}$Ar. With 167 live-days of data, the measured specific activity at the time of atmospheric extraction is [0.964 $\pm$ 0.001 (stat) $\pm$ 0.024 (sys)] Bq/kg$_{\rm atmAr}$ which is consistent with results from other experiments. A cross-check analysis using different event selection criteria provides a consistent result.
Published: 2023
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16. Search for low mass dark matter in DarkSide-50: the bayesian network approach

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cargioli, N., Cariello, M., Carlini, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sandford, E., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present a novel approach for the search of dark matter in the DarkSide-50 experiment, relying on Bayesian Networks. This method incorporates the detector response model into the likelihood function, explicitly maintaining the connection with the quantity of interest. No assumptions about the linearity of the problem or the shape of the probability distribution functions are required, and there is no need to morph signal and background spectra as a function of nuisance parameters. By expressing the problem in terms of Bayesian Networks, we have developed an inference algorithm based on a Markov Chain Monte Carlo to calculate the posterior probability. A clever description of the detector response model in terms of parametric matrices allows us to study the impact of systematic variations of any parameter on the final results. Our approach not only provides the desired information on the parameter of interest, but also potential constraints on the response model. Our results are consistent with recent published analyses and further refine the parameters of the detector response model., Comment: 24 pages, 12 figures, 1 table
Published: 2023
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17. Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells

Author: Hou Y, Cai K, Li J, Chen X, Lai M, Hu Y, Luo Z, Ding X, and Xu D
Subjects: Medicine (General), R5-920
Abstract: Yanhua Hou, Kaiyong Cai, Jinghua Li, Xiuyong Chen, Min Lai, Yan Hu, Zhong Luo, Xingwei Ding, Dawei Xu Key Laboratory of Biorheological Science and Technology and Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, People’s Republic of China Background: The purpose of this study was to investigate the influences of nanoscale wear particles derived from titanium/titanium alloy-based implants on integration of bone. Here we report the potential impact of titanium oxide (TiO2) nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells (MSC) from the cellular level to the molecular level in the Wistar rat. Methods: A series of TiO2 nanoparticles (14 nm, 108 nm, and 196 nm) were synthesized and characterized by scanning electron microscopy and transmission electron microscopy, respectively. Results: The TiO2 nanoparticles had negative effects on cell viability, proliferation, and the cell cycle of MSC in a dose-dependent and size-dependent manner. Confocal laser scanning microscopy was used to investigate the effects of particle internalization on adhesion, spreading, and morphology of MSC. The integrity of the cell membrane, cytoskeleton, and vinculin of MSC were negatively influenced by large TiO2 nanoparticles. Conclusion: The Transwell migration assay and a wound healing model suggested that TiO2 nanoparticles had a strong adverse impact on cell migration as particle size increased (P < 0.01). Furthermore, alkaline phosphatase, gene expression of osteocalcin (OC) and osteopontin (OPN), and mineralization measurements indicate that the size of the TiO2 nanoparticles negatively affected osteogenic differentiation of MSC. Keywords: mesenchymal stem cells, titanium dioxide, nanoparticles, cytotoxicity, adhesion, migration
Published: 2013

18. Numerical Analysis of a Novel Assembled Joint Connecting FCSRC Columns and RC Beams

Author: Tian, S. Y., Ren, F. M., Mo, J. X., Lai, C. L., Lai, M. H., Bao, W., Ceccarelli, Marco, Series Editor, Agrawal, Sunil K., Advisory Editor, Corves, Burkhard, Advisory Editor, Glazunov, Victor, Advisory Editor, Hernández, Alfonso, Advisory Editor, Huang, Tian, Advisory Editor, Jauregui Correa, Juan Carlos, Advisory Editor, Takeda, Yukio, Advisory Editor, and Li, Shaofan, editor
Published: 2024
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19. Edge-Corrugated Shells: Structural Insights About Nervi’s Conception of the Flamino Dome

Author: Lai, M., Rizzi, N. L., Eremeyev, V., Reccia, E., Cazzani, A. M., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Gabriele, Stefano, editor, Manuello Bertetto, Amedeo, editor, Marmo, Francesco, editor, and Micheletti, Andrea, editor
Published: 2024
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20. Corrugated Shells: A Reinforced Concrete Roof Designed by Aldo Favini in Sesto S. Giovanni

Author: Lai, M., Argiolas, R., Musanti, F., Meloni, D., Reccia, E., Cazzani, A. M., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Cui, Zhen-Dong, Series Editor, Gabriele, Stefano, editor, Manuello Bertetto, Amedeo, editor, Marmo, Francesco, editor, and Micheletti, Andrea, editor
Published: 2024
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21. Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

Author: Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Berzin, E., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Chashin, S., Chepurnov, A., Chyhyrynets, E, Cicalò, C., Cifarelli, L., Cintas, D., Cocco, V., Vilda, E. Conde, Consiglio, L., Copello, S., Covone, G., Cross, S., Czudak, P., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Doria, L., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franceschi, A., Franchini, P., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Gorman, D., Diaz, R. Graciani, Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hall, J. B., Hallin, A. L., Hamer, A., Helton, H., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Li, X., Lidey, L., Lipp, J., Lissia, M., Longo, G., Luzzi, L., Macfadyen, O., Machulin, I. N., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Masoni, A., Mavrokoridis, K., Mazzi, A., McDonald, A. B., Messina, A., Milincic, R., Moggi, A., Moharana, A., Monroe, J., Morrocchi, M., Mozhevitina, E. N., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Napolitano, T., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikulin, I., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrino, C., Perotti, F., Pesudo, V., Piacentini, S., Pietropaolo, F., Pino, N., Pira, C., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramachers, Y., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sadashivajois, S., Saffold, T. R., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Scioli, G., Semenov, D. A., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sokolov, A., Spangenberg, M., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Türkoğ, C., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., John, T. Vallivilayil, Van Uffelen, M., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma. M., Wojcik, Ma., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Dark matter lighter than 10 GeV/c$^2$ encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino floor for GeV-scale masses and significant sensitivity down to 10 MeV/c$^2$ considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector's sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies.
Published: 2022
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22. Transport dynamics study of laser-accelerated proton beams and design of double achromatic beam translation system

Author: Zhu, J. G., Lu, H. Y., Zhao, Y., Lai, M. F., Gu, Y. L., Xu, S. X., and Zhou, C. T.
Subjects: Physics - Accelerator Physics
Abstract: Proton beams generated from laser acceleration show merit for their unique spatial (micron-size) and temporal (picosecond) properties, which make them desirable for many potential applications. However, the large energy spread and divergence angle make it difficult to maintain these beam properties after delivery. This hinders the wide application of laser acceleration. In this paper, we design a double achromatic beam translation system (DABTS), based on weak-focusing magnets, to realize achromatic transmission in both the horizontal and vertical directions, and compress the bunch length of the delivered proton beam at the same time. We make use of fringe angles and special steering magnets to effectively reduce the influence of chromatic aberrations and high-order nonlinear terms and realize close to ideal point-to-point optics. We believe this work contributes to the ongoing effort to apply laser accelerators to a variety of fields.
Published: 2022

23. Search for dark matter-nucleon interactions via Migdal effect with DarkSide-50

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fairbairn, M., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Picciau, E., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sanford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: Dark matter elastic scattering off nuclei can result in the excitation and ionization of the recoiling atom through the so-called Migdal effect. The energy deposition from the ionization electron adds to the energy deposited by the recoiling nuclear system and allows for the detection of interactions of sub-GeV/c$^2$ mass dark matter. We present new constraints for sub-GeV/c$^2$ dark matter using the dual-phase liquid argon time projection chamber of the DarkSide-50 experiment with an exposure of (12306 $\pm$ 184) kg d. The analysis is based on the ionization signal alone and significantly enhances the sensitivity of DarkSide-50, enabling sensitivity to dark matter with masses down to 40 MeV/c$^2$. Furthermore, it sets the most stringent upper limit on the spin independent dark matter nucleon cross section for masses below $3.6$ GeV/c$^2$., Comment: 7 pages, 3 figures
Published: 2022
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24. Search for dark matter particle interactions with electron final states with DarkSide-50

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Campos, M. D., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Picciau, E., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sanford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present a search for dark matter particles with sub-GeV/$c^2$ masses whose interactions have final state electrons using the DarkSide-50 experiment's (12306 $\pm$ 184) kg d low-radioactivity liquid argon exposure. By analyzing the ionization signals, we exclude new parameter space for the dark matter-electron cross section $\bar{\sigma}_e$, the axioelectric coupling constant $g_{Ae}$, and the dark photon kinetic mixing parameter $\kappa$. We also set the first dark matter direct-detection constraints on the mixing angle $\left|U_{e4}\right|^2$ for keV sterile neutrinos., Comment: 6 pages, 2 figures
Published: 2022
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25. Search for low-mass dark matter WIMPs with 12 ton-day exposure of DarkSide-50

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Cataudella, V., Cavalcante, P., Cavuoti, S., Chashin, S., Chepurnov, A., Cicalò, C., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Goretti, A. M., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guan, M., Gulino, M., Hackett, B. R., Herner, K., Hessel, T., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kimura, M., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Lychagina, O., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Messina, A., Milincic, R., Monroe, J., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Piacentini, S., Picciau, E., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D. D., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Sanford, E., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We report on the search for dark matter WIMPs in the mass range below 10 GeV/c$^2$, from the analysis of the entire dataset acquired with a low-radioactivity argon target by the DarkSide-50 experiment at LNGS. The new analysis benefits from more accurate calibration of the detector response, improved background model, and better determination of systematic uncertainties, allowing us to accurately model the background rate and spectra down to 0.06 keV$_{er}$. A 90% C.L. exclusion limit for the spin-independent cross section of 3 GeV/c$^2$ mass WIMP on nucleons is set at 6$\times$10$^{-43}$ cm$^2$, about a factor 10 better than the previous DarkSide-50 limit. This analysis extends the exclusion region for spin-independent dark matter interactions below the current experimental constraints in the $[1.2, 3.6]$ GeV/c$^2$ WIMP mass range., Comment: 11 pages, 12 figures
Published: 2022
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26. Numerical Analysis of a Novel Assembled Joint Connecting FCSRC Columns and RC Beams

Author: Tian, S. Y., primary, Ren, F. M., additional, Mo, J. X., additional, Lai, C. L., additional, Lai, M. H., additional, and Bao, W., additional
Published: 2024
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27. Corrugated Shells: A Reinforced Concrete Roof Designed by Aldo Favini in Sesto S. Giovanni

Author: Lai, M., primary, Argiolas, R., additional, Musanti, F., additional, Meloni, D., additional, Reccia, E., additional, and Cazzani, A. M., additional
Published: 2023
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28. Edge-Corrugated Shells: Structural Insights About Nervi’s Conception of the Flamino Dome

Author: Lai, M., primary, Rizzi, N. L., additional, Eremeyev, V., additional, Reccia, E., additional, and Cazzani, A. M., additional
Published: 2023
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29. First direct detection constraints on Planck-scale mass dark matter with multiple-scatter signatures using the DEAP-3600 detector

Author: Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Auty, D. J., Benmansour, H., Bina, C. E., Bonivento, W., Boulay, M. G., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, Y., Cleveland, B. T., Corning, J. M., Daugherty, S., DelGobbo, P., Di Stefano, P., Doria, L., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Goeldi, D., Gorel, P., Graham, K., Grobov, A., Hallin, A. L., Hamstra, M., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Ku{ź}niak, M., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., Levashko, N., Li, X., Lissia, M., Litvinov, O., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McLaughlin, J. B., Mielnichuk, C., Mirasola, L., Monroe, J., Oliviéro, G., Pal, S., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Raj, N., Rand, E. T., Rethmeier, C., Retière, F., Rodríguez-García, I., Roszkowski, L., Ruhland, J. B., García, E. Sanchez, Sánchez-Pastor, T., Santorelli, R., Seth, S., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Stainforth, R., Stringer, M., Sur, B., Vázquez-Jáuregui, E., Viel, S., Walding, J., Waqar, M., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: Dark matter particles with Planck-scale mass ($\simeq10^{19}\text{GeV}/c^2$) arise in well-motivated theories and could be produced by several cosmological mechanisms. Using a blind analysis of data collected over a 813 d live time with DEAP-3600, a 3.3 t single-phase liquid argon-based dark matter experiment at SNOLAB, a search for supermassive dark matter was performed, looking for multiple-scatter signals. No candidate signal events were observed, leading to the first direct detection constraints on Planck-scale mass dark matter. Leading limits constrain dark matter masses between $8.3\times10^{6}$ and $1.2\times10^{19} \text{GeV}/c^2$, and cross sections for scattering on $^{40}$Ar between $1.0\times10^{-23}$ and $2.4\times10^{-18} \text{cm}^2$. These are used to constrain two composite dark matter models.
Published: 2021
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30. Calibration of the liquid argon ionization response to low energy electronic and nuclear recoils with DarkSide-50

Author: The DarkSide collaboration, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cicalò, C., Cocco, A. G., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Morrocchi, M., Mougeot, X., Muratova, V. N., Musico, P., Agasson, A. Navrer, Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Pralavorio, P., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, M. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract: DarkSide-50 has demonstrated the high potential of dual-phase liquid argon time projection chambers in exploring interactions of WIMPs in the GeV/c$^2$ mass range. The technique, based on the detection of the ionization signal amplified via electroluminescence in the gas phase, allows to explore recoil energies down to the sub-keV range. We report here on the DarkSide-50 measurement of the ionization yield of electronic recoils down to $\sim$180~eV$_{er}$, exploiting $^{37}$Ar and $^{39}$Ar decays, and extrapolated to a few ionization electrons with the Thomas-Imel box model. Moreover, we present a model-dependent determination of the ionization response to nuclear recoils down to $\sim$500~eV$_{nr}$, the lowest ever achieved in liquid argon, using \textit{in situ} neutron calibration sources and external datasets from neutron beam experiments., Comment: 11 pages, 12 figures, 1 table
Published: 2021
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31. A study of events with photoelectric emission in the DarkSide-50 liquid argon Time Projection Chamber

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cicalo, C., Cocco, A. G., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., D'Incecco, M., Dionisi, C., Dordei, F., Downing, M., D'Urso, D., Fiorillo, G., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hubaut, F., Hungerford, E. V., Ianni, An., Ippolito, V., Keeter, K., Kendziora, C. L., Kochanek, I., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machulin, I. N., Mapelli, L. P., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Morrocchi, M., Muratova, V. N., Musico, P., Agasson, A. Navrer, Nozdrina, A. O., Oleinik, A., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Pralavorio, P., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Rode, J., Romani, A., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Semenov, D. A., Shchagin, A., Sheshukov, A., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Unzhakov, E. V., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wojcik, Ma. M., Xiao, X., Yang, C., and Zuzel, G.
Subjects: Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract: Finding unequivocal evidence of dark matter interactions in a particle detector is a major objective of physics research. Liquid argon time projection chambers offer a path to probe Weakly Interacting Massive Particles scattering cross sections on nucleus down to the so-called neutrino floor, in a mass range from few GeV's to hundredths of TeV's. Based on the successful operation of the DarkSide-50 detector at LNGS, a new and more sensitive experiment, DarkSide-20k, has been designed and is now under construction. A thorough understanding of the DarkSide-50 detector response and, therefore, of all kind of observed events, is essential for an optimal design of the new experiment. In this paper, we report on a particular set of events, which were not used for dark matter searches. Namely, standard two-pulse scintillation-ionization signals accompanied by a small amplitude third pulse, originating from single or few electrons, in a time window of less than a maximum drift time. We compare our findings to those of a recent paper of the LUX Collaboration (D.S.Akerib et al. Phys.Rev.D 102, 092004). Indeed, both experiments observe events related to photoionization of the cathode. From the measured rate of these events, we estimate for the first time the quantum efficiency of the tetraphenyl butadiene deposited on the DarkSide-50 cathode at wavelengths around 128 nm, in liquid argon. Also, both experiments observe events likely related to photoionization of impurities in the liquid. The probability of photoelectron emission per unit length turns out to be one order of magnitude smaller in DarkSide-50 than in LUX. This result, together with the much larger measured electron lifetime, coherently hints toward a lower concentration of contaminants in DarkSide-50 than in LUX., Comment: 10 pages, 8 figures, 1 table
Published: 2021

32. Protective hydrothermal treatment to improve ion pathway in Ti3C2Tx MXene for high-performance flexible supercapacitors

Author: Lai, M., Chen, K., Wang, D., Cai, P., Sun, L., Zhang, K., Li, B., Yuan, C., Zou, Y., Wang, Z., and Peng, H.
Published: 2024
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33. Pulseshape discrimination against low-energy Ar-39 beta decays in liquid argon with 4.5 tonne-years of DEAP-3600 data

Author: The DEAP Collaboration, Adhikari, P., Ajaj, R., Alpízar-Venegas, M., Amaudruz, P. -A., Auty, D. J., Batygov, M., Beltran, B., Benmansour, H., Bina, C. E., Bonatt, J., Bonivento, W., Boulay, M. G., Broerman, B., Bueno, J. F., Burghardt, P. M., Butcher, A., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, M., Chen, Y., Cleveland, B. T., Corning, J. M., Cranshaw, D., Daugherty, S., DelGobbo, P., Dering, K., DiGioseffo, J., Di Stefano, P., Doria, L., Duncan, F. A., Dunford, M., Ellingwood, E., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Florian, S., Flower, T., Ford, R. J., Gagnon, R., Gallacher, D., Abia, P. García, Garg, S., Giampa, P., Goeldi, D., Golovko, V., Gorel, P., Graham, K., Grant, D. R., Grobov, A., Hallin, A. L., Hamstra, M., Harvey, P. J., Hearns, C., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Kuźniak, M., Lai, M., Langrock, S., Lehnert, B., Leonhardt, A., Levashko, N., Li, X., Lidgard, J., Lindner, T., Lissia, M., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McGinn, T., McLaughlin, J. B., Mehdiyev, R., Mielnichuk, C., Monroe, J., Nadeau, P., Nantais, C., Ng, C., Noble, A. J., O'Dwyer, E., Oliviéro, G., Ouellet, C., Pal, S., Pasuthip, P., Peeters, S. J. M., Perry, M., Pesudo, V., Picciau, E., Piro, M. -C., Pollmann, T. R., Rand, E. T., Rethmeier, C., Retière, F., Rodríguez-García, I., Roszkowski, L., Ruhland, J. B., Sánchez-García, E., Santorelli, R., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Soukup, J., Stainforth, R., Stone, C., Strickland, V., Stringer, M., Sur, B., Tang, J., Vázquez-Jáuregui, E., Viel, S., Walding, J., Waqar, M., Ward, M., Westerdale, S., Willis, J., and Zuñiga-Reyes, A.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The DEAP-3600 detector searches for the scintillation signal from dark matter particles scattering on a 3.3 tonne liquid argon target. The largest background comes from $^{39}$Ar beta decays and is suppressed using pulseshape discrimination (PSD). We use two types of PSD algorithm: the prompt-fraction, which considers the fraction of the scintillation signal in a narrow and a wide time window around the event peak, and the log-likelihood-ratio, which compares the observed photon arrival times to a signal and a background model. We furthermore use two algorithms to determine the number of photons detected at a given time: (1) simply dividing the charge of each PMT pulse by the charge of a single photoelectron, and (2) a likelihood analysis that considers the probability to detect a certain number of photons at a given time, based on a model for the scintillation pulseshape and for afterpulsing in the light detectors. The prompt-fraction performs approximately as well as the log-likelihood-ratio PSD algorithm if the photon detection times are not biased by detector effects. We explain this result using a model for the information carried by scintillation photons as a function of the time when they are detected., Comment: 14 pages, 9 figures
Published: 2021
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34. Separating $^{39}$Ar from $^{40}$Ar by cryogenic distillation with Aria for dark matter searches

Author: DarkSide Collaboration, Agnes, P., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Arba, M., Arpaia, P., Arcelli, S., Ave, M., Avetissov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canesi, E. V., Canci, N., Cappello, G., Caravati, M., C, M., Cargioli, N., Carlini, M., Carnesecchi, F., Castello, P., Castellani, A., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Celano, B., Chashin, S., Chepurnov, A., Cical, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Vilda, E. Conde, Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A. V., Devoto, A., Di Noto, L., Di Eusanio, F., Dionisi, C., Di Stefano, P., Dolganov, G., Dongiovanni, D., Dordei, F., Downing, M., Erjavec, T., Falciano, S., Farenzena, S., Diaz, M. Fernandez, Filip, C., Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Gligan, M. L., Casanueva, V. Goicoechea, Gola, A., Goretti, A. M., Diaz, R. Graciani, Grigoriev, G. Y., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Guetti, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., James, C. C., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kim, S., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., La Delfa, L., La Grasta, D., Lai, M., Lami, N., Langrock, S., Leyton, M., Li, X., Lidey, L., Lippi, F., Lissia, M., Longo, G., Maccioni, N., Machulin, I. N., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S. M., Maricic, J., Marinelli, M., Mart, M., Rojas, A. D. Martinez, Martini, A., Martoff, C. J., Mascia, M., Masetto, M., Masoni, A., Mazzi, A., McDonald, A. B., Mclaughlin, J., Messina, A., Meyers, P. D., Miletic, T., Milincic, R., Miola, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E. N., Mr, T., Muratova, V. N., Murenu, A., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Agasson, A. Navrer, Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pellegrini, L. A., Pellegrino, C., Pelczar, K., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pinna, T., Pocar, A., Podda, P., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Rucaj, M., Sabiu, G. M., Salatino, P., Samoylov, O., S, E., Sandford, E., Sanfilippo, S., Sangiorgio, V. A., Santacroce, V., Santone, D., Santorelli, R., Santucci, A., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D. A., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smith, B., Sokolov, A., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A. M., Zsücs-Balázs, J. Z., Tartaglia, R., Testera, G., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tosti, S., Tricomi, A., Tuveri, M., Unzhakov, E. V., Usai, G., John, T. Vallivilayil, Vescovi, S., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wojcik, Ma. M., Wojcik, Ma., Xiao, X., Yang, C., Zani, A., Zenobio, F., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract: The Aria project consists of a plant, hosting a 350 m cryogenic isotopic distillation column, the tallest ever built, which is currently in the installation phase in a mine shaft at Carbosulcis S.p.A., Nuraxi-Figus (SU), Italy. Aria is one of the pillars of the argon dark-matter search experimental program, lead by the Global Argon Dark Matter Collaboration. Aria was designed to reduce the isotopic abundance of $^{39}$Ar, a $\beta$-emitter of cosmogenic origin, whose activity poses background and pile-up concerns in the detectors, in the argon used for the dark-matter searches, the so-called Underground Argon (UAr). In this paper, we discuss the requirements, design, construction, tests, and projected performance of the plant for the isotopic cryogenic distillation of argon. We also present the successful results of isotopic cryogenic distillation of nitrogen with a prototype plant, operating the column at total reflux.
Published: 2021
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35. Experimental Study on the Behaviour of CFST Columns with Steel Slag Concrete Under Axial Compression

Author: Lin, Y. H., Jin, Y. Y., Ho, J. C. M., Lai, M. H., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Geng, Guoqing, editor, Qian, Xudong, editor, Poh, Leong Hien, editor, and Pang, Sze Dai, editor
Published: 2023
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36. Experimental Study on the Uni-axial Behaviour of MSCFST Columns Considering Concrete’s Wet Packing Density

Author: Mo, J. H., Zeng, M. R., Yang, S. J., Ho, J. C. M., Lai, M. H., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Geng, Guoqing, editor, Qian, Xudong, editor, Poh, Leong Hien, editor, and Pang, Sze Dai, editor
Published: 2023
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37. Load-Carrying Capacity of CFST Columns: Current Design Rules Assessment

Author: Ou, X. L., Ho, J. C. M., Lai, M. H., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Geng, Guoqing, editor, Qian, Xudong, editor, Poh, Leong Hien, editor, and Pang, Sze Dai, editor
Published: 2023
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38. Sensitivity of future liquid argon dark matter search experiments to core-collapse supernova neutrinos

Author: Agnes, P., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Arcelli, S., Ave, M., Avetissov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Olmedo, A. Barrado, Barrillon, P., Basco, A., Batignani, G., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Cappello, G., Caravati, M., Cárdenas-Montes, M., Carlini, M., Carnesecchi, F., Castello, P., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Celano, B., Chashin, S., Chepurnov, A., Chyhyrynets, E, Cicalò, C., Cifarelli, L., Cintas, D., Coccetti, F., Cocco, V., Colocci, M., Vilda, E. Conde, Consiglio, L., Copello, S., Corning, J., Covone, G., Czudak, P., D'Auria, S., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Della Valle, M., Dellacasa, G., De Pasquale, S., Derbin, A. V., Devoto, A., Di Noto, L., Dionisi, C., Di Stefano, P., Dolganov, G., Dordei, F., Doria, L., Downing, M., Erjavec, T., Diaz, M. Fernandez, Fiorillo, G., Franceschi, A., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Galbiati, C., Garbini, M., Abia, P. Garcia, Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Diaz, R. Graciani, Grigoriev, G. Y., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Haranczyk, M., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., James, C. C., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kim, S., Kish, A., Kochanek, I., Kondo, K., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Langrock, S., Leyton, M., Li, X., Lidey, L., Lissia, M., Longo, G., Machulin, I. N., Mapelli, L., Marasciulli, A., Margotti, A., Mari, S. M., Maricic, J., Martínez, M., Rojas, A. D. Martinez, Martoff, C. J., Masoni, A., Mazzi, A., McDonald, A. B., Mclaughlin, J., Messina, A., Meyers, P. D., Miletic, T., Milincic, R., Moggi, A., Moharana, A., Moioli, S., Monroe, J., Morisi, S., Morrocchi, M., Mozhevitina, E. N., Mróz, T., Muratova, V. N., Muscas, C., Musenich, L., Musico, P., Nania, R., Napolitano, T., Agasson, A. Navrer, Nessi, M., Nikulin, I., Nowak, J., Oleinik, A., Oleynikov, V., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pira, C., Pocar, A., Poehlmann, D. M., Pordes, S., Poudel, S. S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescia, S., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Rode, J., Romero, L., Rossi, M., Rubbia, A., Salatino, P., Samoylov, O., García, E. Sánchez, Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Semenov, D. A., Shaw, B., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smith, B., Sokolov, A., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Suvorov, Y., Szelc, A. M., Tartaglia, R., Testera, G., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Usai, G., John, T. Vallivilayil, Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Wada, M., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wojcik, Ma. M., Wojcik, Ma., Xiao, X., Yang, C., Ye, Z., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: Future liquid-argon DarkSide-20k and ARGO detectors, designed for direct dark matter search, will be sensitive also to core-collapse supernova neutrinos, via coherent elastic neutrino-nucleus scattering. This interaction channel is flavor-insensitive with a high-cross section, enabling for a high-statistics neutrino detection with target masses of $\sim$50~t and $\sim$360~t for DarkSide-20k and ARGO, respectively. Thanks to the low-energy threshold of $\sim$0.5~keV$_{nr}$ achievable by exploiting the ionization channel, DarkSide-20k and ARGO have the potential to discover supernova bursts throughout our galaxy and up to the Small Magellanic Cloud, respectively, assuming a 11-M$_{\odot}$ progenitor star. We report also on the sensitivity to the neutronization burst, whose electron neutrino flux is suppressed by oscillations when detected via charged current and elastic scattering. Finally, the accuracies in the reconstruction of the average and total neutrino energy in the different phases of the supernova burst, as well as its time profile, are also discussed, taking into account the expected background and the detector response., Comment: 21 pages, 8 figures
Published: 2020
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39. Strong pinning at high growth rates in Rare Earth Barium Cuprate

Author: Feighan, J., Lai, M. H., Kursumovic, A., Zhang, D., Wang, H., Lee, J. H., Moon, S, and MacManus-Driscoll, J. L.
Subjects: Condensed Matter - Superconductivity
Abstract: We present a simple liquid assisted processing (LAP) method, to be used in-situ during pulsed laser deposition growth to give both rapid growth rates (50 Hz deposition leading to >250 nm/min with a single plume) and strong pinning (improved x 5-10 over plain standard YBCO films grown at similar rates). Achieving these two important features simultaneously has been a serious bottleneck to date. LAP enhances the kinetics of the film growth so that good crystalline perfection can be achieved at up to 60 x faster growth rates than normal, while also enabling artificial pinning centres to be self assembled into fine nanocolumns. In addition, LAP allows for RE mixing (80% of Y with 20% of Yb, Sm, or Yb+Sm), creating effective point-like disorder within the REBCO lattice and which leads to strongly improved pinning at 30 K and below. Overall, LAP is a simple method which could be adopted by other in-situ physical or vapour deposition methods (i.e PLD, MOCVD, evaporation, etc) to significantly enhance both growth rate and performance., Comment: This version has been removed by arXiv administrators as the submitter did not have the legal right to agree to the license at the time of submission
Published: 2020

40. SNEWS 2.0: A Next-Generation SuperNova Early Warning System for Multi-messenger Astronomy

Author: Kharusi, S. Al, BenZvi, S. Y., Bobowski, J. S., Bonivento, W., Brdar, V., Brunner, T., Caden, E., Clark, M., Coleiro, A., Colomer-Molla, M., Crespo-Anadón, J. I., Depoian, A., Dornic, D., Fischer, V., Franco, D., Fulgione, W., Rosso, A. Gallo, Geske, M., Griswold, S., Gromov, M., Haggard, D., Habig, A., Halim, O., Higuera, A., Hill, R., Horiuchi, S., Ishidoshiro, K., Kato, C., Katsavounidis, E., Khaitan, D., Kneller, J. P., Kopec, A., Kulikovskiy, V., Lai, M., Lamoureux, M., Lang, R. F., Li, H. L., Lincetto, M., Lunardini, C., Migenda, J., Milisavljevic, D., McCarthy, M. E., O'Connor, E., O'Sullivan, E., Pagliaroli, G., Patel, D., Peres, R., Pointon, B. W., Qin, J., Raj, N., Renshaw, A., Roeth, A., Rumleskie, J., Scholberg, K., Sheshukov, A., Sonley, T., Strait, M., Takhistov, V., Tamborra, I., Tseng, J., Tunnell, C. D., Vasel, J., Vigorito, C. F., Viren, B., Virtue, C. J., Wang, J. S., Wen, L. J., Winslow, L., Wolfs, F. L. H., Xu, X. J., and Xu, Y.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment
Abstract: The next core-collapse supernova in the Milky Way or its satellites will represent a once-in-a-generation opportunity to obtain detailed information about the explosion of a star and provide significant scientific insight for a variety of fields because of the extreme conditions found within. Supernovae in our galaxy are not only rare on a human timescale but also happen at unscheduled times, so it is crucial to be ready and use all available instruments to capture all possible information from the event. The first indication of a potential stellar explosion will be the arrival of a bright burst of neutrinos. Its observation by multiple detectors worldwide can provide an early warning for the subsequent electromagnetic fireworks, as well as signal to other detectors with significant backgrounds so they can store their recent data. The Supernova Early Warning System (SNEWS) has been operating as a simple coincidence between neutrino experiments in automated mode since 2005. In the current era of multi-messenger astronomy there are new opportunities for SNEWS to optimize sensitivity to science from the next Galactic supernova beyond the simple early alert. This document is the product of a workshop in June 2019 towards design of SNEWS 2.0, an upgraded SNEWS with enhanced capabilities exploiting the unique advantages of prompt neutrino detection to maximize the science gained from such a valuable event., Comment: 66 pages, 11 figures
Published: 2020
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41. Constraints on dark matter-nucleon effective couplings in the presence of kinematically distinct halo substructures using the DEAP-3600 detector

Author: Adhikari, P., Ajaj, R., Bina, C. E., Bonivento, W., Boulay, M. G., Cadeddu, M., Cai, B., Cárdenas-Montes, M., Cavuoti, S., Chen, Y., Cleveland, B. T., Corning, J. M., Daugherty, S., DelGobbo, P., Di Stefano, P., Doria, L., Dunford, M., Erlandson, A., Farahani, S. S., Fatemighomi, N., Fiorillo, G., Gallacher, D., Garcés, E. A., Abia, P. García, Garg, S., Giampa, P., Goeldi, D., Gorel, P., Graham, K., Grobov, A., Hallin, A. L., Hamstra, M., Hugues, T., Ilyasov, A., Joy, A., Jigmeddorj, B., Jillings, C. J., Kamaev, O., Kaur, G., Kemp, A., Kochanek, I., Kuźniak, M., Lai, M., Langrock, S., Lehnert, B., Levashko, N., Li, X., Litvinov, O., Lock, J., Longo, G., Machulin, I., McDonald, A. B., McElroy, T., McLaughlin, J. B., Mielnichuk, C., Monroe, J., Oliviéro, G., Pal, S., Peeters, S. J. M., Pesudo, V., Piro, M. -C., Pollmann, T. R., Rand, E. T., Rethmeier, C., Retière, F., Roszkowski, L., García, E. Sanchez, Sánchez-Pastor, T., Santorelli, R., Sinclair, D., Skensved, P., Smith, B., Smith, N. J. T., Sonley, T., Stainforth, R., Stringer, M., Sur, B., Vázquez-Jáuregui, E., Viel, S., Vincent, A. C., Walding, J., Waqar, M., Westerdale, S., and Zuñiga-Reyes, A.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Astrophysics of Galaxies, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: DEAP-3600 is a single-phase liquid argon detector aiming to directly detect Weakly Interacting Massive Particles (WIMPs), located at SNOLAB (Sudbury, Canada). After analyzing data taken during the first year of operation, a null result was used to place an upper bound on the WIMP-nucleon spin-independent, isoscalar cross section. This study reinterprets this result within a Non-Relativistic Effective Field Theory framework, and further examines how various possible substructures in the local dark matter halo may affect these constraints. Such substructures are hinted at by kinematic structures in the local stellar distribution observed by the Gaia satellite and other recent astronomical surveys. These include the Gaia Sausage (or Enceladus), as well as a number of distinct streams identified in recent studies. Limits are presented for the coupling strength of the effective contact interaction operators $\mathcal{O}_1$, $\mathcal{O}_3$, $\mathcal{O}_5$, $\mathcal{O}_8$, and $\mathcal{O}_{11}$, considering isoscalar, isovector, and xenonphobic scenarios, as well as the specific operators corresponding to millicharge, magnetic dipole, electric dipole, and anapole interactions. The effects of halo substructures on each of these operators are explored as well, showing that the $\mathcal{O}_5$ and $\mathcal{O}_8$ operators are particularly sensitive to the velocity distribution, even at dark matter masses above 100 GeV/$c^2$.
Published: 2020
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42. Effects of Surfactant Solubility on the Hydrodynamics of a Viscous Drop in a DC Electric Field

Author: Nganguia, H., Hu, W. -F., Lai, M. -C., and Young, Y. -N.
Subjects: Physics - Fluid Dynamics
Abstract: The physico-chemistry of surfactants (amphiphilic surface active agents) is often used to control the dynamics of viscous drops and bubbles. Surfactant sorption kinetics has been shown to play a critical role in the deformation of drops in extensional and shear flows, yet to the best of our knowledge these kinetics effects on a viscous drop in an electric fieldhave not been accounted for. In this paper we numerically investigate the effects of sorption kinetics on a surfactant-covered viscous drop in an electric field. Over a range of electric conductivity and permittivity ratios between the interior and exterior fluids, we focus on the dependence of deformation and flow on the transfer parameter $J$, and Biot number $\text{Bi}$ that characterize the extent of surfactant exchange between the drop surface and the bulk. Our findings suggest solubility affects the electrohydrodynamics of a viscous drop in distinct ways as we identify parameter regions where (1) surfactant solubility may alter both the drop deformation and circulation of fluid around a drop, and (2) surfactant solubility affects mainly the flow and not the deformation.
Published: 2020
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43. SiPM-matrix readout of two-phase argon detectors using electroluminescence in the visible and near infrared range

Author: The DarkSide collaboration, Aalseth, C. E., Abdelhakim, S., Agnes, P., Ajaj, R., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Ameli, F., Anstey, J., Antonioli, P., Arba, M., Arcelli, S., Ardito, R., Arnquist, I. J., Arpaia, P., Asner, D. M., Asunskis, A., Ave, M., Back, H. O., Barbaryan, V., Olmedo, A. Barrado, Batignani, G., Bisogni, M. G., Bocci, V., Bondar, A., Bonfini, G., Bonivento, W., Borisova, E., Bottino, B., Boulay, M. G., Bunker, R., Bussino, S., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Candela, A., Cantini, C., Caravati, M., Cariello, M., Carnesecchi, F., Castellani, A., Castello, P., Cavalcante, P., Cavazza, D., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Celano, B., Cereseto, R., Chashin, S., Cheng, W., Chepurnov, A., Cicalò, C., Cifarelli, L., Citterio, M., Coccetti, F., Cocco, V., Colocci, M., Vilda, E. Conde, Consiglio, L., Cossio, F., Covone, G., Crivelli, P., D'Antone, I., D'Incecco, M., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Cecco, S., De Deo, M., De Falco, A., De Gruttola, D., De Guido, G., De Rosa, G., Dellacasa, G., Demontis, P., De Pasquale, S., Derbin, A. V., Devoto, A., Di Eusanio, F., Di Noto, L., Di Pietro, G., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Downing, M., Edalatfar, F., Empl, A., Diaz, M. Fernandez, Filip, C., Fiorillo, G., Fomenko, K., Franceschi, A., Franco, D., Frolov, E., Froudakis, G. E., Funicello, N., Gabriele, F., Gabrieli, A., Galbiati, C., Garbini, M., Abia, P. Garcia, Fora, D. Gascón, Gendotti, A., Ghiano, C., Ghisi, A., Giampa, P., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Gligan, M. L., Gorchakov, O., Grab, M., Diaz, R. Graciani, Grassi, M., Grate, J. W., Grobov, A., Gromov, M., Guan, M., Guerra, M. B. B., Guerzoni, M., Gulino, M., Haaland, R. K., Hackett, B. R., Hallin, A., Haranczyk, M., Harrop, B., Hoppe, E. W., Horikawa, S., Hosseini, B., Hubaut, F., Humble, P., Hungerford, E. V., Ianni, An., Ilyasov, A., Ippolito, V., Jillings, C., Keeter, K., Kendziora, C. L., Kochanek, I., Kondo, K., Kopp, G., Korablev, D., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., La Commara, M., La Delfa, L., Lai, M., Lebois, M., Lehnert, B., Levashko, N., Li, X., Liqiang, Q., Lissia, M., Lodi, G. U., Longo, G., Lussana, R., Luzzi, L., Machado, A. A., Machulin, I. N., Mandarano, A., Manecki, S., Mapelli, L., Margotti, A., Mari, S. M., Mariani, M., Maricic, J., Marinelli, M., Marras, D., Martínez, M., Rojas, A. D. Martinez, Mascia, M., Mason, J., Masoni, A., McDonald, A. B., Messina, A., Miletic, T., Milincic, R., Moggi, A., Moioli, S., Monroe, J., Morrocchi, M., Mroz, T., Mu, W., Muratova, V. N., Murphy, S., Muscas, C., Musico, P., Nania, R., Napolitano, T., Agasson, A. Navrer, Nessi, M., Nikulin, I., Nosov, V., Nowak, J. A., Oleinik, A., Oleynikov, V., Orsini, M., Ortica, F., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Pazzona, F., Peeters, S., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pelliccia, N., Perotti, F., Pesudo, V., Picciau, E., Pietropaolo, F., Pocar, A., Pollmann, T. R., Portaluppi, D., Poudel, S. S., Pralavorio, P., Price, D., Radics, B., Raffaelli, F., Ragusa, F., Razeti, M., Regenfus, C., Renshaw, A. L., Rescia, S., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Rode, J., Romani, A., Romero, L., Rossi, N., Rubbia, A., Sala, P., Salatino, P., Samoylov, O., García, E. Sánchez, Sandford, E., Sanfilippo, S., Sant, M., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Segreto, E., Seifert, A., Semenov, D. A., Shchagin, A., Sheshukov, A., Siddhanta, S., Simeone, M., Singh, P. N., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Sobrero, G., Sokolov, A., Sotnikov, A., Stainforth, R., Steri, A., Stracka, S., Strickland, V., Suffritti, G. B., Sulis, S., Suvorov, Y., Szelc, A. M., Tartaglia, R., Testera, G., Thorpe, T., Tonazzo, A., Tosi, A., Tuveri, M., Unzhakov, E. V., Usai, G., Vacca, A., Vázquez-Jáuregui, E., Viant, T., Viel, S., Villa, F., Vishneva, A., Vogelaar, R. B., Wahl, J., Walding, J. J., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, R., Wilson, J., Wojcik, Ma. M., Wojcik, Ma., Wu, S., Xiao, X., Yang, C., Ye, Z., Zuffa, M., and Zuzel, G.
Subjects: Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract: Proportional electroluminescence (EL) in noble gases is used in two-phase detectors for dark matter searches to record (in the gas phase) the ionization signal induced by particle scattering in the liquid phase. The "standard" EL mechanism is considered to be due to noble gas excimer emission in the vacuum ultraviolet (VUV). In addition, there are two alternative mechanisms, producing light in the visible and near infrared (NIR) ranges. The first is due to bremsstrahlung of electrons scattered on neutral atoms ("neutral bremsstrahlung", NBrS). The second, responsible for electron avalanche scintillation in the NIR at higher electric fields, is due to transitions between excited atomic states. In this work, we have for the first time demonstrated two alternative techniques of the optical readout of two-phase argon detectors, in the visible and NIR range, using a silicon photomultiplier matrix and electroluminescence due to either neutral bremsstrahlung or avalanche scintillation. The amplitude yield and position resolution were measured for these readout techniques, which allowed to assess the detection threshold for electron and nuclear recoils in two-phase argon detectors for dark matter searches. To the best of our knowledge, this is the first practical application of the NBrS effect in detection science., Comment: 26 pages, 22 figures, 3 tables
Published: 2020
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44. Effective field theory interactions for liquid argon target in DarkSide-50 experiment

Author: Collaboration, The DarkSide-50, Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonfini, G., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Candela, A., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cicalò, C., Cocco, A. G., Covone, G., D'Angelo, D., Davini, S., DeCandia, A., DeCecco, S., DeDeo, M., DeFilippis, G., DeRosa, G., Derbin, A. V., Devoto, A., DiEusanio, F., D'Incecco, M., DiPietro, G., Dionisi, C., Downing, M., D'Urso, D., Edkins, E., Empl, A., Fiorillo, G., Fomenko, K., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giagu, S., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Granato, F., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hughes, D., Humble, P., Hungerford, E. V., Ianni, Al., Ianni, An., Ippolito, V., Johnson, T. N., Keeter, K., Kendziora, C. L., Kochanek, I., Koh, G., Korablev, D., Korga, G., Kubankin, A., Kuss, M., LaCommara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machado, A. A., Machulin, I. N., Mandarano, A., Mapelli, L., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Monte, A., Morrocchi, M., Muratova, V. N., Musico, P., NavrerAgasson, A., Nozdrina, A. O., Oleinik, A., Orsini, M., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Qian, H., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Riffard, Q., Romani, A., Rossi, B., Rossi, N., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Segreto, E., Semenov, D. A., Shchagin, A., Sheshukov, A., Singh, P. N., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stanford, C., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Trinchese, P., Unzhakov, E. V., Verducci, M., Vishneva, A., Vogelaar, R. B., Wada, M., Waldrop, T. J., Wang, H., Wang, Y., Watson, A. W., Westerdale, S., Wojcik, M. M., Xiang, X., Xiao, X., Yang, C., Ye, Z., Zhu, C., and Zuzel, G.
Subjects: High Energy Physics - Experiment, High Energy Physics - Phenomenology, Physics - Instrumentation and Detectors
Abstract: We reanalize data collected with the DarkSide-50 experiment and recently used to set limits on the spin-independent interaction rate of weakly interacting massive particles (WIMPs) on argon nuclei with an effective field theory framework. The dataset corresponds to a total (16660 $\pm$ 270) kg d exposure using a target of low-radioactivity argon extracted from underground sources. We obtain upper limits on the effective couplings of the 12 leading operators in the nonrelativistic systematic expansion. For each effective coupling we set constraints on WIMP-nucleon cross sections, setting upper limits between $2.4 \times 10^{-45} \, \mathrm{cm}^2$ and $2.3 \times 10^{-42} \, \mathrm{cm}^2$ (8.9 $\times 10^{-45} \, \mathrm{cm}^2$ and 6.0 $\times 10^{-42} \, \mathrm{cm}^2$) for WIMPs of mass of 100 $\mathrm{GeV/c^2}$ (1000 $\mathrm{GeV/c^2}$) at 90\% confidence level., Comment: Accepted by PRD
Published: 2020

45. Design and construction of a new detector to measure ultra-low radioactive-isotope contamination of argon

Author: The DarkSide Collaboration, Aalseth, C. E., Abdelhakim, S., Acerbi, F., Agnes, P., Ajaj, R., Albuquerque, I. F. M., Alexander, T., Alici, A., Alton, A. K., Amaudruz, P., Ameli, F., Anstey, J., Antonioli, P., Arba, M., Arcelli, S., Ardito, R., Arnquist, I. J., Arpaia, P., Asner, D. M., Asunskis, A., Ave, M., Back, H. O., Olmedo, A. Barrado, Batignani, G., Bisogni, M. G., Bocci, V., Bondar, A., Bonfini, G., Bonivento, W., Borisova, E., Bottino, B., Boulay, M. G., Bunker, R., Bussino, S., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Candela, A., Cantini, C., Caravati, M., Cariello, M., Carnesecchi, F., Carpinelli, M., Castellani, A., Castello, P., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavazza, D., Cavuoti, S., Cebrian, S., Ruiz, J. M. Cela, Celano, B., Cereseto, R., Cheng, W., Chepurnov, A., Cicalò, C., Cifarelli, L., Citterio, M., Cocco, A. G., Cocco, V., Colocci, M., Consiglio, L., Cossio, F., Covone, G., Crivelli, P., D'Antone, I., D'Incecco, M., D'Urso, D., Rolo, M. D. Da Rocha, Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Deo, M., De Falco, A., De Filippis, G., De Gruttola, D., De Guido, G., De Rosa, G., Dellacasa, G., Demontis, P., DePaquale, S., Derbin, A. V., Devoto, A., Di Eusanio, F., Di Noto, L., Di Pietro, G., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Downing, M., Edalatfar, F., Empl, A., Diaz, M. Fernandez, Ferri, A., Filip, C., Fiorillo, G., Fomenko, K., Franceschi, A., Franco, D., Froudakis, G. E., Gabriele, F., Gabrieli, A., Galbiati, C., Abia, P. Garcia, Fora, D. Gascón, Gendotti, A., Ghiano, C., Ghisi, A., Giagu, S., Giampa, P., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Gligan, M. L., Gola, A., Gorchakov, O., Grab, M., Diaz, R. Graciani, Granato, F., Grassi, M., Grate, J. W., Grigoriev, G. Y., Grobov, A., Gromov, M., Guan, M., Guerra, M. B. B., Guerzoni, M., Gulino, M., Haaland, R. K., Hackett, B. R., Hallin, A., Harrop, B., Hoppe, E. W., Horikawa, S., Hosseini, B., Hubaut, F., Humble, P., Hungerford, E. V., Ianni, An., Ilyasov, A., Ippolito, V., Jillings, C., Keeter, K., Kendziora, C. L., Kim, S., Kochanek, I., Kondo, K., Kopp, G., Korablev, D., Korga, G., Kubankin, A., Kugathasan, R., Kuss, M., Kuźniak, M., La Commara, M., La Delfa, L., Lai, M., Langrock, S., Lebois, M., Lehnert, B., Levashko, N., Li, X., Liqiang, Q., Lissia, M., Lodi, G. U., Longo, G., Manzano, R. López, Lussana, R., Luzzi, L., Machado, A. A., Machulin, I. N., Mandarano, A., Mapelli, L., Marcante, M., Margotti, A., Mari, S. M., Mariani, M., Maricic, J., Marinelli, M., Marras, D., Martínez, M., Morales, J. J. Martínez, Rojas, A. D. Martinez, Martoff, C. J., Mascia, M., Mason, J., Masoni, A., Mazzi, A., McDonald, A. B., Messina, A., Meyers, P. D., Miletic, T., Milincic, R., Moggi, A., Moioli, S., Monroe, J., Morrocchi, M., Mroz, T., Mu, W., Muratova, V. N., Murphy, S., Muscas, C., Musico, P., Nania, R., Napolitano, T., Agasson, A. Navrer, Nessi, M., Nikulin, I., Oleinik, A., Oleynikov, V., Orsini, M., Ortica, F., Pagani, L., Pallavicini, M., Palmas, S., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pavletcov, V., Pazzona, F., Peeters, S., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pelliccia, N., Perotti, F., Pesudo, V., Picciau, E., Piemonte, C., Pietropaolo, F., Pocar, A., Pollman, T., Portaluppi, D., Poudel, S. S., Pralavorio, P., Price, D., Radics, B., Raffaelli, F., Ragusa, F., Razeti, M., Razeto, A., Regazzoni, V., Regenfus, C., Renshaw, A. L., Rescia, S., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Romani, A., Romero, L., Rossi, N., Rubbia, A., Sablone, D., Sala, P., Salatino, P., Samoylov, O., García, E. Sánchez, Sanfilippo, S., Sant, M., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schlitzer, B., Scioli, G., Segreto, E., Seifert, A., Semenov, D. A., Shchagin, A., Sheshukov, A., Siddhanta, S., Simeone, M., Singh, P. N., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Sobrero, G., Sokolov, A., Sotnikov, A., Stainforth, R., Steri, A., Stracka, S., Strickland, V., Suffritti, G. B., Sulis, S., Suvorov, Y., Szelc, A. M., Tartaglia, R., Testera, G., Thorpe, T., Tonazzo, A., Tosi, A., Tuveri, M., Unzhakov, E. V., Usai, G., Vacca, A., Vázquez-Jáuregui, E., Verducci, M., Viant, T., Viel, S., Villa, F., Vishneva, A., Vogelaar, R. B., Wada, M., Wahl, J., Walding, J. J., Wang, H., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, R., Wilson, J., Wojcik, Marcin, Wojcik, Mariusz, Wu, S., Xiao, X., Yang, C., Ye, Z., Zuffa, M., and Zuzel, G.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: Large liquid argon detectors offer one of the best avenues for the detection of galactic weakly interacting massive particles (WIMPs) via their scattering on atomic nuclei. The liquid argon target allows exquisite discrimination between nuclear and electron recoil signals via pulse-shape discrimination of the scintillation signals. Atmospheric argon (AAr), however, has a naturally occurring radioactive isotope, $^{39}$Ar, a $\beta$ emitter of cosmogenic origin. For large detectors, the atmospheric $^{39}$Ar activity poses pile-up concerns. The use of argon extracted from underground wells, deprived of $^{39}$Ar, is key to the physics potential of these experiments. The DarkSide-20k dark matter search experiment will operate a dual-phase time projection chamber with 50 tonnes of radio-pure underground argon (UAr), that was shown to be depleted of $^{39}$Ar with respect to AAr by a factor larger than 1400. Assessing the $^{39}$Ar content of the UAr during extraction is crucial for the success of DarkSide-20k, as well as for future experiments of the Global Argon Dark Matter Collaboration (GADMC). This will be carried out by the DArT in ArDM experiment, a small chamber made with extremely radio-pure materials that will be placed at the centre of the ArDM detector, in the Canfranc Underground Laboratory (LSC) in Spain. The ArDM LAr volume acts as an active veto for background radioactivity, mostly $\gamma$-rays from the ArDM detector materials and the surrounding rock. This article describes the DArT in ArDM project, including the chamber design and construction, and reviews the background required to achieve the expected performance of the detector., Comment: 13 pages, 8 figures. Corresponding author: E. S\'anchez Garc\'ia
Published: 2020
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46. Phase transition dynamics in one-dimensional halide perovskite crystals

Author: Lai, M, Lei, T, Zhang, Y, Jin, J, Steele, JA, and Yang, P
Subjects: Applied Physics, Macromolecular and Materials Chemistry, Materials Engineering, Mechanical Engineering
Abstract: Abstract: Triiodide perovskites CsPbI 3, CsSnI 3, and FAPbI 3 (where FA is formamidinium) are highly promising materials for a range of optoelectronic applications in energy conversion. However, they are thermodynamically unstable at room temperature, preferring to form low-temperature (low-T) non-perovskite phases with one-dimensional anisotropic crystal structures. While such thermodynamic behavior represents a major obstacle toward realizing high-performance devices based on their high-temperature (high-T) perovskite phases, the underlying phase transition dynamics are still not well understood. Here we use in situ optical micro-spectroscopy to quantitatively study the transition from the low-T to high-T phases in individual CsSnI 3 and FAPbI 3 nanowires. We reveal a large blueshift in the photoluminescence (PL) peak (~38 meV) at the low-T/high-T two-phase interface of partially transitioned FAPbI 3 wire, which may result from the lattice distortion at the phase boundary. Compared to the experimentally derived activation energy of CsSnI3 (~1.93 eV), the activation energy of FAPbI 3 is relatively small (~0.84 eV), indicating a lower kinetic energy barrier when transitioning from a face-sharing octahedral configuration to a corner-sharing one. Further, the phase propagation rate in CsSnI3 is observed to be relatively high, which may be attributed to a high concentration of Sn vacancies. Our results could not only facilitate a deeper understanding of phase transition dynamics in halide perovskites with anisotropic crystal structures, but also enable controllable manipulation of optoelectronic properties via local phase engineering. Impact Statement: Metal halide perovskites are a new class of semiconductors with great promise for a variety of optoelectronic applications. Owing to their soft ionic lattice, halide perovskites often exhibit rich phase transitions between different crystal structures, frequently from the “active” perovskite phases to undesirable “inactive” non-perovskite phases. Understanding and controlling this transition is vital for developing stable, high-performance devices. However, there is limited understanding on how different symmetry, crystal structure, and defect would impact such a phase transition process. In this report, in situ optical micro-spectroscopy is used to systematically investigate the phase transitions from non-perovskite to perovskite phases in individual CsSnI3 and FAPbI3 wires. Compared to the transition from an edge-sharing octahedral non-perovskite structure to a corner-sharing perovskite structure in CsSnI3, the activation energy for the FAPbI3 phase transition is relatively small, indicating a lower energy barrier when starting from a face-sharing octahedral structure in FAPbI3. The high concentration of Sn vacancies is probably responsible for the much higher phase propagation rate in CsSnI3 when compared to a CsPbBrxI3-x system with the same crystal structure but different halide vacancies. Our experimental results expand theknowledge of phase transition in halide perovskites and offer important guidance toward rationally designing more stable and efficient perovskite devices.
Published: 2021

47. Analysis of hygrothermally induced fiber fracture in single fiber composite using fiber Bragg grating

Author: Cugnoni J., Lai M., and Botsis J.
Subjects: Physics, QC1-999
Abstract: Hygro-thermal ageing of composite materials introduces a modification in the material properties of its constituents and the development of stresses that can lead to severe local damage like fracture of the reinforcing fibers and de-bonding of the latter from the matrix. The study of the complex stress field generated by this induced damage is helpful in designing more resistant materials. Modelling strain-stress filed in the vicinity of these discontinuities has led to the development of different analytical models like for instance shear lag models based on simplification assumptions. Recently the development of embedded optical sensors allowed to shed light on the assumptions made, since they can be used, at the same time, as reinforcement and sensors and thus being capable to give information on the strain distributions during the evolution of the damage. In this work a single fiber composite, whose reinforcement is an optical sensor, is used in order to investigate the complex strain field generated by the fiber fracture caused by the matrix swelling during water uptake.
Published: 2010
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48. Thin corrugated-edge shells inspired by Nervi’s dome: Numerical insight about their mechanical behaviour

Author: Lai, M., Zucca, M., Meloni, D., Reccia, E., and Cazzani, A.
Published: 2023
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49. Study of cosmogenic activation above ground for the DarkSide-20k experiment

Author: Elersich, A., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I.F.M., Alexander, T., Alton, A.K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I.Ch., Azzolini, O., Back, H.O., Balmforth, Z., Barrado-Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W.M., Bottino, B., Boulay, M.G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J.M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Colaiuda, D., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M.D., Davini, S., De Cecco, S., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A.V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G.K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B.R., Hallin, A.L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A.A., Kendziora, C.L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I.N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S.M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C.J., Matteucci, G., Mavrokoridis, K., McDonald, A.B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V.N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solórzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P.A., Pelczar, K., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D.M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A.L., Rescigno, M., Retiere, F., Rignanese, L.P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M.A., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F.G., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M.D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A.M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T.N., Tonazzo, A., Tricomi, A., Unzhakov, E.V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R.B., Vossebeld, J., Wada, M., Walczak, M.B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma.M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M.P.
Published: 2023
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50. Measurement of the ion fraction and mobility of $^{218}$Po produced in $^{222}$Rn decays in liquid argon

Author: Agnes, P., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Ave, M., Back, H. O., Batignani, G., Biery, K., Bocci, V., Bonfini, G., Bonivento, W. M., Bottino, B., Bussino, S., Cadeddu, M., Cadoni, M., Calaprice, F., Caminata, A., Canci, N., Candela, A., Caravati, M., Cariello, M., Carlini, M., Carpinelli, M., Catalanotti, S., Cataudella, V., Cavalcante, P., Cavuoti, S., Chepurnov, A., Cicalo, C., Cocco, A. G., Covone, G., D'Angelo, D., Davini, S., De Candia, A., De Cecco, S., De Deo, M., De Filippis, G., De Rosa, G., Derbin, A. V., Devoto, A., Di Eusanio, F., D'Incecco, M., Di Pietro, G., Dionisi, C., Downing, M., D'Urso, D., Edkins, E., Empl, A., Fiorillo, G., Fomenko, K., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giagu, S., Giganti, C., Giovanetti, G. K., Gorchakov, O., Goretti, A. M., Granato, F., Grobov, A., Gromov, M., Guan, M., Guardincerri, Y., Gulino, M., Hackett, B. R., Herner, K., Hosseini, B., Hughes, D., Humble, P., Hungerford, E. V., Ianni, Al., Ianni, An., Ippolito, V., Johnson, T. N., Keeter, K., Kendziora, C. L., Kochanek, I., Koh, G., Korablev, D., Korga, G., Kubankin, A., Kuss, M., La Commara, M., Lai, M., Li, X., Lissia, M., Longo, G., Machado, A. A., Machulin, I. N., Mandarano, A., Mapelli, L., Mari, S. M., Maricic, J., Martoff, C. J., Messina, A., Meyers, P. D., Milincic, R., Monte, A., Morrocchi, M., Muratova, V. N., Musico, P., Agasson, A. Navrer, Nozdrina, A. O., Oleinik, A., Orsini, M., Ortica, F., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Pelczar, K., Pelliccia, N., Picciau, E., Pocar, A., Pordes, S., Poudel, S. S., Qian, H., Ragusa, F., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Riffard, Q., Romani, A., Rossi, B., Rossi, N., Sablone, D., Samoylov, O., Sands, W., Sanfilippo, S., Savarese, C., Schlitzer, B., Segreto, E., Semenov, D. A., Shchagin, A., Sheshukov, A., Singh, P. N., Skorokhvatov, M. D., Smirnov, O., Sotnikov, A., Stanford, C., Stracka, S., Suvorov, Y., Tartaglia, R., Testera, G., Tonazzo, A., Trinchese, P., Unzhakov, E. V., Verducci, M., Vishneva, A., Vogelaar, R. B., Wada, M., Waldrop, T. J., Wang, H., Wang, Y., Watson, A. W., Westerdale, S., Wojcik, M. M., Xiang, X., Xiao, X., Yang, C., Ye, Z., Zhu, C., and Zuzel, G.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Physics - Instrumentation and Detectors
Abstract: We report measurements of the charged daughter fraction of $^{218}$Po as a result of the $^{222}$Rn alpha decay, and the mobility of $^{218}$Po$^+$ ions, using radon-polonium coincidences from the $^{238}$U chain identified in 532 live-days of DarkSide-50 WIMP-search data. The fraction of $^{218}$Po that is charged is found to be 0.37$\pm$0.03 and the mobility of $^{218}$Po$^+$ is (8.6$\pm$0.1)$\times$10$^{-4}$$\frac{\text{cm}^2}{\text{Vs}}$.
Published: 2019
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