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Background: Problematic use of internet (PUI) may have negative impacts on psychological distress and quality of life (QoL). This situation might be more profound in people with attention-deficit/hyperactivity disorder (ADHD) due to poorer behavioral control and regulatory capacity. However, there is little evidence regarding mediated effects in the associations between PUI, psychological distress, and QoL in people with ADHD. Aims: To investigate mediating effects of psychological distress in the associations of problematic smartphone use (PSPU), problematic use of social media (PUSM), and problematic gaming (PG) with QoL in individuals with ADHD. Methods and Procedures: PUI behaviors of participants with ADHD (n = 99) were assessed using the Smartphone Application-Based Addiction Scale, Bergen Social Media Addiction Scale, and Internet Gaming Disorder-Short Form. Psychological distress was assessed using the Depression, Anxiety, Stress Scale and QoL using the Kid-KINDL. Outcomes and Results: Psychological distress mediated the associations between PUI and different domains of QoL, except for self-esteem QoL. There were also positively direct effects between PG and physical QoL, PUSM and friends' QoL, and PSPU and physical QoL. Conclusions and Implications: PUI may associate with poor QoL in people with ADHD via psychological distress. Programs on reducing PUI for people with ADHD are needed. [ABSTRACT FROM AUTHOR]

Objective To compare and analyze the current situation of Medical Technology development in domestic and foreign famous medical schools. Methods By searching U.S. News & World Report Best Global Universities Rankings, Academic Rankings of World Universities (ARWU), and the websites of domestic and foreign medical schools and Ministry of Education of China, and interviewing the experts, this study summarized the differences of Medical Technology discipline in China and aboard in three aspects, i.e. major setting, enrollment conditions and academic degree granting, and disciplinary strength. Results·In the U.S. News discipline rankings for undergraduate education,"Radiology, Nuclear Medicine & Medical Imaging" was the only subject in the field of Medical Technology. As for the discipline rankings for graduate education, the subject category of"Medicine" included"Radiology", and the subject category of"Health"contained several subjects related with Medical Technology, including"Audiology" "Rehabilitation Counseling" "Speech-Language Pathology" "Occupational Therapy"and"Physical Therapy" . In the ARWU,"Medical Technology" discipline contained"Medical Laboratory Technology""Neuroimaging"and"Radiology, Nuclear Medicine & Medical Imaging" . At the stage of undergraduate education in China, Medical Technology-related majors included 13 majors in the category of"Medical Technology"and 3 majors in the category of"Clinical Medicine" . At the stage of graduate education in China, Medical Technology-related majors included 11 majors in the category of "Medicine"and 2 majors in the category of"Natural Science" . Taking Rehabilitation-related majors as examples of enrollment condition and academic degree granting, there were many master's and doctoral programs abroad, and the enrollment conditions were flexible. However, the Rehabilitation-related majors in China concentrated on the undergraduate education; the graduate education enrollment required relevant professional background. In the ARWU, the top five universities in"Medical Technology"in Chinese mainland ranked 76-200 globally. The indicators of publications in the journals of Q1 range and in the top journals as well as the honours of prominent prizes were relatively low. Conclusion·There is still a gap in the international rankings of Medical Technology discipline between domestic universities and the top universities abroad. The construction of world's first-class discipline of Medical Technology in China will be boosted by optimizing the major setting, adjusting the professional education system and academic degree granting, and strengthening the scientific research. [ABSTRACT FROM AUTHOR]

Highlights: [•] Pure α-Bi2O3 nanowires were grown by catalyst-driven vapor transport method. [•] The Au nanoparticles facilitate the nucleation and growth rate. [•] A two-step growth model was proposed. [•] Intense visible luminescence was observed at room temperature. [ABSTRACT FROM AUTHOR]

Abstract: Selective serotonin reuptake inhibitors (SSRIs) have been reported to reduce platelet aggregation induced by ADP. ADP induces platelet aggregation through two purinergic receptors P2Y1 and P2Y12. We characterized the inhibitory properties of SSRIs on ADP-induced platelet aggregation and investigated the effects of SSRIs on the signaling pathways downstream of P2Y1 and P2Y12 receptors. Specific antagonists were used to evaluate which purinergic receptor-mediated aggregation was influenced by SSRIs. The primary phase of ADP-induced aggregation was not inhibited by citalopram. Citalopram failed to influence ADP-induced platelet shape change, intracellular calcium mobilization and the early phosphorylation of PKCα. Differently, citalopram inhibited the secondary phase of ADP-induced platelet aggregation in a concentration-dependent manner. Other SSRIs, including fluoxetine and sertraline, exhibited the same anti-platelet effects. Under P2Y1 blockade, citalopram inhibited platelet aggregation and integrin αIIbβ3 activation in response to ADP, indicating that citalopram inhibited P2Y12-mediated aggregation. Citalopram concentration-dependently inhibited the phosphorylation of Akt, GSK3β, p38 MAPK and Syk induced by ADP, but showed no effect on the decrease of cAMP and VASP phosphorylation. With integrin αIIbβ3 blockade, however, the phosphorylation of Akt triggered by ADP was unaltered by the addition of citalopram. Taken together, under the stimulation of ADP, SSRIs inhibit the amplification of platelet aggregation secondary to the activation of P2Y12 receptor, and subsequently reduce the activation of the downstream molecules of the outside-in signaling pathways. [Copyright &y& Elsevier]

Background & Problems: A total of 20 cases of children with epilepsy implemented electroencephalography (EEG) recording examinations in our ward between January 1st and March 10th, 2016. Fifteen (75%) of the recordings were incompletely stored, indicating that the EEG recordings storage integrity in our unit was 25%. Incomplete storage of these recordings results in prolonged hospital stays and negatively affects the ability of doctors to provide accurate diagnoses., Purpose: This project was developed to increase the EEG recording storage integrity for epileptic children to 100%., Resolutions: Improvement plans included reinforcing related promotions, formulating a standard flowchart for EEG recording education, making "warm bear signs", designing simple cartoon health-education flashcards, and providing in-service education., Results: The EEG recording storage integrity for epileptic children in our ward rose to 100% after implementation of the resolution measures, which achieved our purpose., Conclusions: We want to share this experience to improve the storage integrity of EEG recordings at other hospitals and clinics. The greatest benefit of this project was that the family members of children with epilepsy perceived more strongly the effort and care of the nursing staffs during examinations, which reduces the costs of healthcare.