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Your search keyword '"Lai, Yau-Ming"' showing total 20 results
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20 results on '"Lai, Yau-Ming"'

8. Sonographic investigation into the morphological change of median nerve in the dominant hand of normal subject under pitching with various loading and duration

Author

Lai, Yau Ming

Subjects
Comparative studies, Occupational / Environmental hazards, Ultrasound, Musculoskeletal soft tissue
Abstract

Aim Methods and materials Results Conclusion Personal information References, Aim: Increase in loading and duration during pinching are significant risk factors of carpal tunnel syndrome (CTS)[1]. The morphological change of the median nerve (MN) under pinching has been studied but studies on the morphological change of the MN...

Published
2014
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9. Evaluation of grid and non-grid techniques on digital mammographic image: An image quality and radiation dose study

Author

Lai, Yau Ming

Subjects
Dosimetry, Biological effects, Breast, Mammography
Abstract

Aim Methods and materials Results Conclusion Personal information References, Aim: Current mammographic practice often applies grid. Grid technique is believed to produce better images but higher radiation dose on patients. Non-grid technique, however, allows the use of a lower radiationdose, in particular to subject with small...

Published
2014
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10. Investigation of breast tissue pattern variation in digital mammogram using fractal analysis

Author

Lai, Yau Ming

Subjects
Fractal analysis, Breast, Image manipulation / Reconstruction, Mammography, Cancer
Abstract

Aim Methods and materials Results Conclusion Personal information References, Aim: Breast cancer accounts for one-third of all cancer diagnoses among women. It is the second highest mortality rate of all cancer deaths [1]. Breast cancer risk is associated with mammographic image density.Changes in mammographic image density may be...

Published
2014
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11. Ultrasonometry of patella-condyle distance: Effects of gender, knee flexion and leg dominance

Author

Lai, Yau Ming

Subjects
Comparative studies, Bones, Ultrasound, Extremities, Athletic injuries
Abstract

Aim Methods and materials Results Conclusion Personal information References, Aim: Patellofemoral pain syndrome (PFPS) is a very common knee problem. Patella mal-alignment [1]and mal-tracking [2]are considered as themajor etiology. Current imaging method, CT and MRI, cannot provide dynamic assessment of the joint in full range of...

Published
2014
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12. Investigation of exercise effect and menstruation on bone status using calcaneal quantitative ultrasound

Author

Lai, Yau Ming

Subjects
Bones, Ultrasound, Osteoporosis, Experimental investigations
Abstract

Aim Methods and materials Results Conclusion Personal information References, Aim: According to the Utah paradigm [1], mechanical loading via exercise is the driving force to maintain bone health, with the aids of other non-mechanical agents, including calcium, vitamin D, cytokines and hormones. Estrogen plays an important role in...

Published
2014
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13. Erratum: A Novel, Stable, Estradiol-Stimulating, Osteogenic Yam Protein with Potential for the Treatment of Menopausal Syndrome

Author

Wong, Kam Lok, primary, Lai, Yau Ming, additional, Li, Ka Wan, additional, Lee, Kai Fai, additional, Ng, Tzi Bun, additional, Cheung, Ho Pan, additional, Zhang, Yan Bo, additional, Lao, Lixing, additional, Wong, Ricky Ngok-Shun, additional, Shaw, Pang Chui, additional, Wong, Jack Ho, additional, Zhang, Zhang-Jin, additional, Lam, Jenny Ka Wing, additional, Ye, Wen-cai, additional, and Sze, Stephen Cho Wing, additional

Published
2015
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16. Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential

Author

Wong, Kam Lok, primary, Wong, Ricky Ngok Shun, additional, Zhang, Liang, additional, Liu, Wing Keung, additional, NG, Tzi Bun, additional, Shaw, Pang Chui, additional, Kwok, Philip Chi Lip, additional, Lai, Yau Ming, additional, Zhang, Zhang Jin, additional, Zhang, Yanbo, additional, Tong, Yao, additional, Cheung, Ho-Pan, additional, Lu, Jia, additional, and Sze, Stephen Cho Wing, additional

Published
2014
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17. Bone adaptation under mechanical influence: regional differences in bone mineral density, degree of mineralisation, mirco-arhitecture evaluated by pQCT, BSE imaging and microCT.

Author

Lai, Yau Ming., Chinese University of Hong Kong Graduate School. Division of Orthopaedics & Traumatology., Lai, Yau Ming., and Chinese University of Hong Kong Graduate School. Division of Orthopaedics & Traumatology.

Abstract

Lai Yau Ming., "August 2006.", Thesis (Ph.D.)--Chinese University of Hong Kong, 2006., Includes bibliographical references (p. 260-290)., Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web., s in English and Chinese., http://library.cuhk.edu.hk/record=b6074239, Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Published
2006

20. A Novel, Stable, Estradiol-Stimulating, Osteogenic Yam Protein with Potential for the Treatment of Menopausal Syndrome.

Author

Wong KL, Lai YM, Li KW, Lee KF, Ng TB, Cheung HP, Zhang YB, Lao L, Wong RN, Shaw PC, Wong JH, Zhang ZJ, Lam JK, Ye WC, and Sze SC

Subjects
Amino Acid Sequence, Animals, Aromatase genetics, Aromatase metabolism, Bone Density, Bone and Bones diagnostic imaging, Brain-Derived Neurotrophic Factor metabolism, Cell Line, Cell Survival drug effects, Female, Menopause, Molecular Sequence Data, Osteoporosis prevention & control, Ovary cytology, Peptides chemistry, Peptides therapeutic use, Plant Proteins chemistry, Prefrontal Cortex metabolism, RNA, Messenger metabolism, Rats, Rats, Sprague-Dawley, Receptor, trkB metabolism, Receptors, FSH genetics, Receptors, FSH metabolism, Rhizome metabolism, X-Ray Microtomography, Dioscorea metabolism, Estradiol biosynthesis, Plant Proteins metabolism
Abstract

A novel protein, designated as DOI, isolated from the Chinese yam (Dioscorea opposita Thunb.) could be the first protein drug for the treatment of menopausal syndrome and an alternative to hormone replacement therapy (HRT), which is known to have undesirable side effects. DOI is an acid- and thermo-stable protein with a distinctive N-terminal sequence Gly-Ile-Gly-Lys-Ile-Thr-Thr-Tyr-Trp-Gly-Gln-Tyr-Ser-Asp-Glu-Pro-Ser-Leu-Thr-Glu. DOI was found to stimulate estradiol biosynthesis in rat ovarian granulosa cells; induce estradiol and progesterone secretion in 16- to 18-month-old female Sprague Dawley rats by upregulating expressions of follicle-stimulating hormone receptor and ovarian aromatase; counteract the progression of osteoporosis and augment bone mineral density; and improve cognitive functioning by upregulating protein expressions of brain-derived neurotrophic factor and TrkB receptors in the prefrontal cortex. Furthermore, DOI did not stimulate the proliferation of breast cancer and ovarian cancer cells, which suggest it could be a more efficacious and safer alternative to HRT., Competing Interests: Findings from this study have been used to apply for patents (Patent Cooperation Treaty Patent Pub. No.: WO/2013/023617; U.S. Patent Pub. No.: US20130217626 A1; European Patent Pub. No.: EP 2750684 A1; China Patent pub. No.: CN103945854 A)

Published
2015
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